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You searched for subject:(Cirugia Abdominal). Showing records 1 – 2 of 2 total matches.

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1. Juvany Gómez, Montserrat. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.

Degree: Departament de Medicina, 2015, Universitat Internacional de Catalunya

Previous studies demonstrated that increased levels of C-reactive protein (CRP) after colo-rectal surgery are correlated to postoperative organ-space surgical site infection (OS-SSI) even at 48 hours time point. Such early inflammatory response might suggest that intraoperative haemodynamic factors might influence intestinal anastomosis healing. Objective: To evaluate the correlation between early postoperative venous lactate, CRP at 48 hours and intraoperative haemodynamics and the incidence of OS-SSI in patients operated on elective colorectal surgery with anastomosis. Materials and methods. From March 2013 to August 2014, all patients undergoing colorectal surgery with anastomosis were prospectively included. Levels of venous lactate were measured at the end of surgery (L-PO) and at 6 (L-6) and 24 hours afterwards (L-24). CRP levels at postoperative 48 hours (CRP-48) were also measured. We compared lactate levels and CRP values in patients with and without OS-SSI infection. Proportion of time that patients developed intraoperative systolic hypotension (SBP<100 mmHg) or tachycardia (>90 bpm) were also assessed. Data are summarized as mean ± SD. To analyze data, Student t-test and a logistic regression model with L-0 and CRP-48 with a ROC curve of this model were performed. Results. One hundred patients were included, with an age of 69±11 years-old. Forty-four percent of patients were operated by laparoscopic approach. Eleven out of 100 patients (11%) complained OS-SSI. OS-SSI patients had significantly higher venous lactate levels at L-PO and at L-24 (3,2 vs 1,5, p<0,001 and 1,8 vs 1,2, p=0,0002, mmol/L, respectively). Overall, patients with L-PO >2,5 mmol/L had higher CRP-48 levels (140±85 vs. 78±57 mg/L, respectively, p=0,001). With the logistic regression model with L-PO and CRP-48 and ROC curve of this model: in patients with more than 0,26 of probability, OS-SSI should be discarded (AUC 0,899). Analysing haemodynamics behaviour, patients who developed OS-SSI remained hypotensive (50 % vs 30%, p=0,03) and tachycardic (18% vs 5%, p=0,02) for a longer period of time. Conclusions. Early postoperative venous lactate and CRP at 48 hours correlated to OS-SSI appearance. Determination of biological markers and haemodynamics goal-oriented intraoperative management might improve the postoperative outcome. Advisors/Committee Members: false (authoremailshow), Guirao Garriga, Xavier (director), Badia Pérez, Josep Maria (director), false (authorsendemail).

Subjects/Keywords: Lactat venós; Infecció òrgan-espai; Cirurgia colo-rectal; Cirugia Abdominal; 61

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Juvany Gómez, M. (2015). Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. (Thesis). Universitat Internacional de Catalunya. Retrieved from http://hdl.handle.net/10803/362920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Juvany Gómez, Montserrat. “Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.” 2015. Thesis, Universitat Internacional de Catalunya. Accessed September 22, 2020. http://hdl.handle.net/10803/362920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Juvany Gómez, Montserrat. “Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós.” 2015. Web. 22 Sep 2020.

Vancouver:

Juvany Gómez M. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. [Internet] [Thesis]. Universitat Internacional de Catalunya; 2015. [cited 2020 Sep 22]. Available from: http://hdl.handle.net/10803/362920.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Juvany Gómez M. Identificació Precoç de la Infecció Greu del Lloc Quirúrgic en Cirurgia Colo-Rectal Electiva Mitjançant els Marcadors Biològics Proteïna C-Reactiva i Lactat Venós. [Thesis]. Universitat Internacional de Catalunya; 2015. Available from: http://hdl.handle.net/10803/362920

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Universitat Autònoma de Barcelona

2. García-Oria, Miguel Juan. Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal.

Degree: Departament de Cirurgia, 2009, Universitat Autònoma de Barcelona

Introduction: Obesity has reached epidemic proportions in developed countries. Colorectal cancers is also in those countries, the second most frequent diagnosed cancer. There are no definitive data in medical literature, regarding the impact that overweight have in the outcomes, of colorectal cancer treatment. Goals: To asses the influence of obesity and preobesity in postoperative and intraoperative morbidity and mortality, long term survival, tumour characteristics and clinical parameters, as well as identify prognostic factors for patients submitted to elective colorectal cancer surgery. Patients and methods: Inclusion criteria were patients submitted to surgery for colorectal cancer at the “Hospital Universitari de Girona“ during the period 1999-2001. All surgeries were elective with intention to cure, Dukes D patients were excluded. Patients were grouped by Body Mass Index (BMI) into underweight (<18.5), normalweight (18.5-24.9), preobese (25.0-29.9) and obese (>30.0). 38 different parameters (epidemiological, nutritional, laboratory, histological, surgical, morbidity, comorbidity, short and long term mortality) were studied. We performed an univariate analysis for all patients. One bivariate analysis for BMI and other for long term survival were also performed, and finally a multivariate analysis to asses independent prognostic factors of long term survival. Results: 369 patients, 213 (57.8 %) with colon cancer (CC) and 156 (42.3%) with rectal cancer (RC) were included into the study. 224 (60.7%) male and 145 (39.3%) female, average age were 66.3 years. 7 (1.9%) were underweight, 182 (49.5%) normalweight, 118 (32.1%) preobese and 61 (16.6%) obese. 121 (32.8%) patients had postoperative morbidity, 6 (1.6%) was the first month mortality. There were no statistically significant differences between BMI groups regarding morbidity and mortality, in the first postoperative month, neither in long term survival with a follow up of 13.2 years. Preobese and obese patients have had more preoperative comorbidities (p=0.002), and also higher levels of preoperative serum proteins (p=0.002), albumine (p=0.032) and complement system C3 (p=0.034), meanwhile alpha 1 antitripsine were lower than in normalweight patients (p=0.046). With regard to lymph nodes, patients with higher BMI, had more lymph nodes affected (p=0.041), and more undifferentiated tumours (p=0.011), when the cancer was in the colon, and more lymph nodes affected and higher tumour stage (p=0.023), if the neoplasm was rectal cancer. In multivariate analysis, independent prognostic factors for long term survival were, ASA score, tumour stage, age and surgical technique. Conclusions: Preobesity and obesity, does not have influence in postoperative morbidity or mortality, neither long term survival, of the patients submitted to elective colorectal cancer surgery, although there has been identified influence in other parameters like comorbidities, nutritional status or tumour characteristics. Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Armengol Carrasco, Manuel (director), Codina Cazador, Antoni (director), true (authorsendemail).

Subjects/Keywords: Ciencies mèdiques; Ciencias médicas; Health sciencs; Cirugia abdominal; Cirugía abdominal; Abdominal surgery; Cirugia-Oncologia; Cirugia-Oncología; Surgery-Oncology; Ciències de la Salut; 617

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

García-Oria, M. J. (2009). Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/288304

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

García-Oria, Miguel Juan. “Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal.” 2009. Thesis, Universitat Autònoma de Barcelona. Accessed September 22, 2020. http://hdl.handle.net/10803/288304.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

García-Oria, Miguel Juan. “Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal.” 2009. Web. 22 Sep 2020.

Vancouver:

García-Oria MJ. Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2009. [cited 2020 Sep 22]. Available from: http://hdl.handle.net/10803/288304.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

García-Oria MJ. Influencia del sobrepeso y la obesidad, en la morbimortalidad perioperatoria y supervivencia a largo plazo, de pacientes intervenidos electivamente por cáncer colorrectal. [Thesis]. Universitat Autònoma de Barcelona; 2009. Available from: http://hdl.handle.net/10803/288304

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.