subject:(Chromosomes)

University of Tasmania

1. Geard, Charles Ray. Studies in chromosome structure and replication.

Degree: 1969, University of Tasmania

URL: https://eprints.utas.edu.au/19943/1/whole_GeardCharlesRay1969_thesis.pdf

► A quantitative analysis of sister chromatid exchanges and labelling patterns in H 3 thymidine labelled second division (post isotope incorporation) chromosomes of Vicia faba has… (more)

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Geard, C. R. (1969). Studies in chromosome structure and replication. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/19943/1/whole_GeardCharlesRay1969_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Geard, Charles Ray. “Studies in chromosome structure and replication.” 1969. Thesis, University of Tasmania. Accessed March 07, 2021. https://eprints.utas.edu.au/19943/1/whole_GeardCharlesRay1969_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Geard, Charles Ray. “Studies in chromosome structure and replication.” 1969. Web. 07 Mar 2021.

Vancouver:

Geard CR. Studies in chromosome structure and replication. [Internet] [Thesis]. University of Tasmania; 1969. [cited 2021 Mar 07]. Available from: https://eprints.utas.edu.au/19943/1/whole_GeardCharlesRay1969_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Geard CR. Studies in chromosome structure and replication. [Thesis]. University of Tasmania; 1969. Available from: https://eprints.utas.edu.au/19943/1/whole_GeardCharlesRay1969_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University

2. Thompson, Steven Risley. Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen).

Degree: MS, Zoology, 1963, Oregon State University

URL: http://hdl.handle.net/1957/48948

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Thompson, S. R. (1963). Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen). (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/48948

Chicago Manual of Style (16^th Edition):

Thompson, Steven Risley. “Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen).” 1963. Masters Thesis, Oregon State University. Accessed March 07, 2021. http://hdl.handle.net/1957/48948.

MLA Handbook (7^th Edition):

Thompson, Steven Risley. “Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen).” 1963. Web. 07 Mar 2021.

Vancouver:

Thompson SR. Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen). [Internet] [Masters thesis]. Oregon State University; 1963. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1957/48948.

Council of Science Editors:

Thompson SR. Induction of gross deletions in ring-X and rod-X chromosomes of Drosophila melanogaster (Meigen). [Masters Thesis]. Oregon State University; 1963. Available from: http://hdl.handle.net/1957/48948

Oregon State University

3. Neeley, John Charles. Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen).

Degree: MS, Zoology, 1963, Oregon State University

URL: http://hdl.handle.net/1957/48909

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Neeley, J. C. (1963). Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen). (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/48909

Chicago Manual of Style (16^th Edition):

Neeley, John Charles. “Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen).” 1963. Masters Thesis, Oregon State University. Accessed March 07, 2021. http://hdl.handle.net/1957/48909.

MLA Handbook (7^th Edition):

Neeley, John Charles. “Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen).” 1963. Web. 07 Mar 2021.

Vancouver:

Neeley JC. Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen). [Internet] [Masters thesis]. Oregon State University; 1963. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1957/48909.

Council of Science Editors:

Neeley JC. Crossing-over in a reversed acrocentric x-chromosome in triploid Drosophila melanogaster (Meigen). [Masters Thesis]. Oregon State University; 1963. Available from: http://hdl.handle.net/1957/48909

Oregon State University

4. Swedberg, Gertrude Laliah Salmon. A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen).

Degree: MS, Zoology, 1959, Oregon State University

URL: http://hdl.handle.net/1957/50164

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Swedberg, G. L. S. (1959). A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen). (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/50164

Chicago Manual of Style (16^th Edition):

Swedberg, Gertrude Laliah Salmon. “A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen).” 1959. Masters Thesis, Oregon State University. Accessed March 07, 2021. http://hdl.handle.net/1957/50164.

MLA Handbook (7^th Edition):

Swedberg, Gertrude Laliah Salmon. “A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen).” 1959. Web. 07 Mar 2021.

Vancouver:

Swedberg GLS. A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen). [Internet] [Masters thesis]. Oregon State University; 1959. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1957/50164.

Council of Science Editors:

Swedberg GLS. A spectrophotometric study of protein and deoxyribonucleic acid in nuclei of varying Y chromosome dosage in Drosophila melanogaster (Meigen). [Masters Thesis]. Oregon State University; 1959. Available from: http://hdl.handle.net/1957/50164

Oregon State University

5. Haertel, John David. A comparative study of the chromosomes from five species of the genus Rana.

Degree: PhD, Zoology, 1969, Oregon State University

URL: http://hdl.handle.net/1957/46012

► The karyotypes of five species of ranid frogs were determined from metaphase plates of bone marrow cells. The colchicine, hypotonic- citrate, blaze-dry technique was used… (more)

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Haertel, J. D. (1969). A comparative study of the chromosomes from five species of the genus Rana. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/46012

Chicago Manual of Style (16^th Edition):

Haertel, John David. “A comparative study of the chromosomes from five species of the genus Rana.” 1969. Doctoral Dissertation, Oregon State University. Accessed March 07, 2021. http://hdl.handle.net/1957/46012.

MLA Handbook (7^th Edition):

Haertel, John David. “A comparative study of the chromosomes from five species of the genus Rana.” 1969. Web. 07 Mar 2021.

Vancouver:

Haertel JD. A comparative study of the chromosomes from five species of the genus Rana. [Internet] [Doctoral dissertation]. Oregon State University; 1969. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1957/46012.

Council of Science Editors:

Haertel JD. A comparative study of the chromosomes from five species of the genus Rana. [Doctoral Dissertation]. Oregon State University; 1969. Available from: http://hdl.handle.net/1957/46012

Michigan State University

6. Adangapuram, Thamby Ninan. Induction of chromosome damage by ethylenimines and related compounds.

Degree: PhD, Department of Botany and Plant Pathology, 1967, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:34338

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Adangapuram, T. N. (1967). Induction of chromosome damage by ethylenimines and related compounds. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:34338

Chicago Manual of Style (16^th Edition):

Adangapuram, Thamby Ninan. “Induction of chromosome damage by ethylenimines and related compounds.” 1967. Doctoral Dissertation, Michigan State University. Accessed March 07, 2021. http://etd.lib.msu.edu/islandora/object/etd:34338.

MLA Handbook (7^th Edition):

Adangapuram, Thamby Ninan. “Induction of chromosome damage by ethylenimines and related compounds.” 1967. Web. 07 Mar 2021.

Vancouver:

Adangapuram TN. Induction of chromosome damage by ethylenimines and related compounds. [Internet] [Doctoral dissertation]. Michigan State University; 1967. [cited 2021 Mar 07]. Available from: http://etd.lib.msu.edu/islandora/object/etd:34338.

Council of Science Editors:

Adangapuram TN. Induction of chromosome damage by ethylenimines and related compounds. [Doctoral Dissertation]. Michigan State University; 1967. Available from: http://etd.lib.msu.edu/islandora/object/etd:34338

7. Heberlig, Raymond Dale. Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray.

Degree: Botany, 1964, Texas Tech University

URL: http://hdl.handle.net/2346/17266

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Heberlig, R. D. (1964). Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray. (Thesis). Texas Tech University. Retrieved from http://hdl.handle.net/2346/17266

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Heberlig, Raymond Dale. “Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray.” 1964. Thesis, Texas Tech University. Accessed March 07, 2021. http://hdl.handle.net/2346/17266.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Heberlig, Raymond Dale. “Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray.” 1964. Web. 07 Mar 2021.

Vancouver:

Heberlig RD. Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray. [Internet] [Thesis]. Texas Tech University; 1964. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2346/17266.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Heberlig RD. Effects of environment on meiosis in Chamaesaracha sordida (Dunal) gray. [Thesis]. Texas Tech University; 1964. Available from: http://hdl.handle.net/2346/17266

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McGill University

8. Sparrow, Arnold Hicks, 1914-. Studies on the chromosome spiralization cycle in trillium.

Degree: PhD, Department of Genetics, 1941, McGill University

URL: https://escholarship.mcgill.ca/downloads/hx11xh86z.pdf ; https://escholarship.mcgill.ca/concern/theses/02871009k

► "Broadly speaking, the sum-total of the concepts involved in any material phenomenon is a constant (P); and if we simplify or diminish the complexity of… (more)

Subjects/Keywords: Chromosomes.

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APA (6^th Edition):

Sparrow, Arnold Hicks, 1. (1941). Studies on the chromosome spiralization cycle in trillium. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/hx11xh86z.pdf ; https://escholarship.mcgill.ca/concern/theses/02871009k

Chicago Manual of Style (16^th Edition):

Sparrow, Arnold Hicks, 1914-. “Studies on the chromosome spiralization cycle in trillium.” 1941. Doctoral Dissertation, McGill University. Accessed March 07, 2021. https://escholarship.mcgill.ca/downloads/hx11xh86z.pdf ; https://escholarship.mcgill.ca/concern/theses/02871009k.

MLA Handbook (7^th Edition):

Sparrow, Arnold Hicks, 1914-. “Studies on the chromosome spiralization cycle in trillium.” 1941. Web. 07 Mar 2021.

Vancouver:

Sparrow, Arnold Hicks 1. Studies on the chromosome spiralization cycle in trillium. [Internet] [Doctoral dissertation]. McGill University; 1941. [cited 2021 Mar 07]. Available from: https://escholarship.mcgill.ca/downloads/hx11xh86z.pdf ; https://escholarship.mcgill.ca/concern/theses/02871009k.

Council of Science Editors:

Sparrow, Arnold Hicks 1. Studies on the chromosome spiralization cycle in trillium. [Doctoral Dissertation]. McGill University; 1941. Available from: https://escholarship.mcgill.ca/downloads/hx11xh86z.pdf ; https://escholarship.mcgill.ca/concern/theses/02871009k

McGill University

9. Wilson, G. B. (George Bernard), 1914-. The structure and behaviour of chromosomes during meiosis in Trillium erectum L.

Degree: PhD, Department of Genetics, 1939, McGill University

URL: https://escholarship.mcgill.ca/downloads/2j62s789w.pdf ; https://escholarship.mcgill.ca/concern/theses/0c483n15b

► Genetics and Cytology have, in the past twenty years, combined to place the chromosome in the important role of chief physical link between parent and… (more)

Subjects/Keywords: Chromosomes.

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APA (6^th Edition):

Wilson, G. B. (George Bernard), 1. (1939). The structure and behaviour of chromosomes during meiosis in Trillium erectum L. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/2j62s789w.pdf ; https://escholarship.mcgill.ca/concern/theses/0c483n15b

Chicago Manual of Style (16^th Edition):

Wilson, G. B. (George Bernard), 1914-. “The structure and behaviour of chromosomes during meiosis in Trillium erectum L.” 1939. Doctoral Dissertation, McGill University. Accessed March 07, 2021. https://escholarship.mcgill.ca/downloads/2j62s789w.pdf ; https://escholarship.mcgill.ca/concern/theses/0c483n15b.

MLA Handbook (7^th Edition):

Wilson, G. B. (George Bernard), 1914-. “The structure and behaviour of chromosomes during meiosis in Trillium erectum L.” 1939. Web. 07 Mar 2021.

Vancouver:

Wilson, G. B. (George Bernard) 1. The structure and behaviour of chromosomes during meiosis in Trillium erectum L. [Internet] [Doctoral dissertation]. McGill University; 1939. [cited 2021 Mar 07]. Available from: https://escholarship.mcgill.ca/downloads/2j62s789w.pdf ; https://escholarship.mcgill.ca/concern/theses/0c483n15b.

Council of Science Editors:

Wilson, G. B. (George Bernard) 1. The structure and behaviour of chromosomes during meiosis in Trillium erectum L. [Doctoral Dissertation]. McGill University; 1939. Available from: https://escholarship.mcgill.ca/downloads/2j62s789w.pdf ; https://escholarship.mcgill.ca/concern/theses/0c483n15b

University of British Columbia

10. Murphy, Mary. Chromosome abberations in Galtonia Candicans.

Degree: MA- MA, Botany, 1943, University of British Columbia

URL: http://hdl.handle.net/2429/39044

[]

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Murphy, M. (1943). Chromosome abberations in Galtonia Candicans. (Masters Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/39044

Chicago Manual of Style (16^th Edition):

Murphy, Mary. “Chromosome abberations in Galtonia Candicans.” 1943. Masters Thesis, University of British Columbia. Accessed March 07, 2021. http://hdl.handle.net/2429/39044.

MLA Handbook (7^th Edition):

Murphy, Mary. “Chromosome abberations in Galtonia Candicans.” 1943. Web. 07 Mar 2021.

Vancouver:

Murphy M. Chromosome abberations in Galtonia Candicans. [Internet] [Masters thesis]. University of British Columbia; 1943. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2429/39044.

Council of Science Editors:

Murphy M. Chromosome abberations in Galtonia Candicans. [Masters Thesis]. University of British Columbia; 1943. Available from: http://hdl.handle.net/2429/39044

Michigan State University

11. Lapenson, David Phillip, 1954-. Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II).

Degree: PhD, Department of Biochemistry, 1983, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:18883

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Lapenson, David Phillip, 1. (1983). Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II). (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:18883

Chicago Manual of Style (16^th Edition):

Lapenson, David Phillip, 1954-. “Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II).” 1983. Doctoral Dissertation, Michigan State University. Accessed March 07, 2021. http://etd.lib.msu.edu/islandora/object/etd:18883.

MLA Handbook (7^th Edition):

Lapenson, David Phillip, 1954-. “Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II).” 1983. Web. 07 Mar 2021.

Vancouver:

Lapenson, David Phillip 1. Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II). [Internet] [Doctoral dissertation]. Michigan State University; 1983. [cited 2021 Mar 07]. Available from: http://etd.lib.msu.edu/islandora/object/etd:18883.

Council of Science Editors:

Lapenson, David Phillip 1. Studies on mammalian metaphase chromosomes and characterization of phosphofructokinase membrane binding and activity inhibition by hexacyanoferrate (II). [Doctoral Dissertation]. Michigan State University; 1983. Available from: http://etd.lib.msu.edu/islandora/object/etd:18883

Michigan State University

12. Yoon, Sei Byung. Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster.

Degree: PhD, 1961, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:37100

Subjects/Keywords: Chromosomes

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APA (6^th Edition):

Yoon, S. B. (1961). Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:37100

Chicago Manual of Style (16^th Edition):

Yoon, Sei Byung. “Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster.” 1961. Doctoral Dissertation, Michigan State University. Accessed March 07, 2021. http://etd.lib.msu.edu/islandora/object/etd:37100.

MLA Handbook (7^th Edition):

Yoon, Sei Byung. “Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster.” 1961. Web. 07 Mar 2021.

Vancouver:

Yoon SB. Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster. [Internet] [Doctoral dissertation]. Michigan State University; 1961. [cited 2021 Mar 07]. Available from: http://etd.lib.msu.edu/islandora/object/etd:37100.

Council of Science Editors:

Yoon SB. Studies on the effect of X and Y chromosomes on protein synthesis and spermatozoal development in Drosophila melanogaster. [Doctoral Dissertation]. Michigan State University; 1961. Available from: http://etd.lib.msu.edu/islandora/object/etd:37100

13. Roche, Andrew Ian de la. Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato.

Degree: Plant & Soil Sciences, 1966, University of Massachusetts

URL: https://scholarworks.umass.edu/theses/3237

Subjects/Keywords: Chromosomes.

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APA (6^th Edition):

Roche, A. I. d. l. (1966). Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato. (Masters Thesis). University of Massachusetts. Retrieved from https://scholarworks.umass.edu/theses/3237

Chicago Manual of Style (16^th Edition):

Roche, Andrew Ian de la. “Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato.” 1966. Masters Thesis, University of Massachusetts. Accessed March 07, 2021. https://scholarworks.umass.edu/theses/3237.

MLA Handbook (7^th Edition):

Roche, Andrew Ian de la. “Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato.” 1966. Web. 07 Mar 2021.

Vancouver:

Roche AIdl. Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato. [Internet] [Masters thesis]. University of Massachusetts; 1966. [cited 2021 Mar 07]. Available from: https://scholarworks.umass.edu/theses/3237.

Council of Science Editors:

Roche AIdl. Genetic interrelations of six yellow-green mutants and mapping of Neglecta1 and YG6 genes on chromosome XI of tomato. [Masters Thesis]. University of Massachusetts; 1966. Available from: https://scholarworks.umass.edu/theses/3237

Rutgers University

14. Jones, Daniel William, 1987-. Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines.

Degree: MS, Cell and Developmental Biology, 2015, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/48520/

► Creation of a Novel ETV6-Cre Reporter Mouse Model for ETV6-Related Fusion Protein Analysis: The ETV6 gene is one of the most commonly targeted genes for… (more)

▼ Creation of a Novel ETV6-Cre Reporter Mouse Model for ETV6-Related Fusion Protein Analysis: The ETV6 gene is one of the most commonly targeted genes for chromosomal translocation in leukemia. ETV6 has been found to play a key role in hematopoiesis and maintenance of embryonic vascular development, yet its role in B-cell precursor acute lymphoblastic leukemia has yet to be fully determined in respect to both gene expression localization and interactions with other proteins. In this study, we focus on the creation of a novel transgenic line of ETV6-mCherry-CreERT2 mice that can be used both as a reporter for ETV6 expression and to drive ETV6-specific expression of Cre-ERT2 in mice with ETV6-related fusions using recombineering strategies. Characterization of Ink4ab/ Vav-Cre Transgenic Mice Lines: The Ink4ab genetic locus encodes for three essential proteins involved in tumor suppression, designated p15, p16, and p19 in mice. Full knockout models of this locus have been shown to exhibit accelerated tumorigenesis in multiple forms of cancer (Krimpenfort et al., 2007). By combining the Vav promoter, a promoter that first targets fetal liver hematopoietic stem cells, with a Cre-Lox system to allow full knock out of Ink4ab in only hematopoietic stem cells, we theorize the possibility of creating a hematopoietic system-based malignancy. Dissections have shown that Ink4ab+/-; Vav-Cre+ and Ink4ab-/-; Vav-Cre+ mice have splenic hyperplasia, tumor growth in both liver and spleen, and ascites in the peritoneal cavity. Peripheral blood analysis of Ink4ab-/-; Vav-Cre+ mice showed the presence of lymphoblasts, abnormal erythrocytes, and apoptotic neutrophils. Immunohistochemical staining has shown that Ink4ab-/-; Vav-Cre+ mice have increased apoptosis in T-cells, decreased mature B-cell and T-cell presence, increased cellular proliferation, deregulated cell cycle, and leukemia and lymphoma formation. These studies reveal a novel model for studying hematopoietic cell development, leukemia formation, and lymphoma formation. Advisors/Committee Members: Xie, Ping (chair), Padgett, Richard W. (internal member), Sabaawy, Hatem E. (internal member).

Subjects/Keywords: Chromosomes; Leukemia

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APA (6^th Edition):

Jones, Daniel William, 1. (2015). Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/48520/

Chicago Manual of Style (16^th Edition):

Jones, Daniel William, 1987-. “Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines.” 2015. Masters Thesis, Rutgers University. Accessed March 07, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/48520/.

MLA Handbook (7^th Edition):

Jones, Daniel William, 1987-. “Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines.” 2015. Web. 07 Mar 2021.

Vancouver:

Jones, Daniel William 1. Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines. [Internet] [Masters thesis]. Rutgers University; 2015. [cited 2021 Mar 07]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48520/.

Council of Science Editors:

Jones, Daniel William 1. Creation of a novel ETV6-Cre reporter mouse model for ETV6-related fusion protein analysis and characterization of Ink4ab/ Vav-Cre transgenic mice Lines. [Masters Thesis]. Rutgers University; 2015. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48520/

15. Muir, Kyle. Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex.

Degree: Docteur es, Biologie Structurale et Nanobiologie, 2016, Université Grenoble Alpes (ComUE)

URL: http://www.theses.fr/2016GREAV005

►

L'appariement des chromatides sœurs est un prérequis fondamental pour la ségrégation fidèle du génome. Cet assemblage est précisément régulé par plusieurs facteurs modulant la solidarité… (more)

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L'appariement des chromatides sœurs est un prérequis fondamental pour la ségrégation fidèle du génome. Cet assemblage est précisément régulé par plusieurs facteurs modulant la solidarité entre le complexe formant la cohésine et les chromosomes. Un de ces facteurs, Pds5, engage la cohésine par le biais de SCC1 et participe à la fois au renforcement de la cohésion, et inversement à la libération de la cohésine de la chromatine. Dans cette thèse, la structure cristalline du complexe entre les protéines de levure Pds5 et SCC1 est présentée. Celle-ci permet la compréhension de la fonction moléculaire de Pds5. Pds5 forme un « heat-repeat » allongé qui se lie à SCC1 via une interface dont sa séquence reste conservée. Suite à la caractérisation biologique et biochimique de cette structure, cette thèse démontre que l'intégrité de l'interface entre Pds5 et SCC1 est indispensable pour le recrutement de Pds5 à la cohésine et que son abrogation conduit à la perte de la cohésion entre les chromatides sœurs ainsi que la perte de la viabilité cellulaire. Les résultats présentés dans cette thèse suggèrent donc que Pds5 est constitutivement lie au cœur de la sous-unité de la cohésine.

Sister chromatid cohesion is a fundamental prerequisite to faithful genome segregation. Cohesion is precisely regulated by accessory factors that modulate the stability with which the cohesin complex embraces chromosomes. One of these factors, Pds5, engages cohesin through Scc1 and participates both in the enhancement of cohesion, and conversely in mediating the release of cohesin from chromatin. In this thesis the crystal structure of a complex between budding yeast Pds5 and Scc1 is presented, thus elucidating the molecular basis of Pds5 function. Pds5 forms an elongated HEAT repeat that binds to Scc1 via a conserved surface patch. Through complementary cell biological and biochemical characterisation of this structure, the thesis demonstrates that the integrity of the Pds5–Scc1 interface is indispensable for the recruitment of Pds5 to cohesin, and that its abrogation results in loss of sister chromatid cohesion and cell viability. The results presented in this thesis therefore suggest that Pds5 is a constitutively bound, core subunit of cohesin.

Advisors/Committee Members: Panne, Daniel (thesis director).

Subjects/Keywords: Chromosomes; Cohésion; Épigénétique; Chromosomes; Cohesion; Epigenetics; 570

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APA (6^th Edition):

Muir, K. (2016). Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex. (Doctoral Dissertation). Université Grenoble Alpes (ComUE). Retrieved from http://www.theses.fr/2016GREAV005

Chicago Manual of Style (16^th Edition):

Muir, Kyle. “Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex.” 2016. Doctoral Dissertation, Université Grenoble Alpes (ComUE). Accessed March 07, 2021. http://www.theses.fr/2016GREAV005.

MLA Handbook (7^th Edition):

Muir, Kyle. “Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex.” 2016. Web. 07 Mar 2021.

Vancouver:

Muir K. Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex. [Internet] [Doctoral dissertation]. Université Grenoble Alpes (ComUE); 2016. [cited 2021 Mar 07]. Available from: http://www.theses.fr/2016GREAV005.

Council of Science Editors:

Muir K. Caractérisation biochimique et biophysique du complexe cohésine : Biochemical and biophysical characterisation of the Cohesin complex. [Doctoral Dissertation]. Université Grenoble Alpes (ComUE); 2016. Available from: http://www.theses.fr/2016GREAV005

University of Victoria

16. Wilson, Michael Davies. Comparative and functional genomic analysis of a gene dense region at chromosome 7q22.

Degree: Dept. of Biology, 2008, University of Victoria

URL: http://hdl.handle.net/1828/643

► Genomic sequencing, comparative genomic analysis and mouse transgenics were used to investigate two regions of human chromosome 7 that are associated with chromosomal loss, duplication… (more)

▼ Genomic sequencing, comparative genomic analysis and mouse transgenics were used to investigate two regions of human chromosome 7 that are associated with chromosomal loss, duplication and disease. Williams-Beuren syndrome (WBS) is a complex neuro-developmental disorder arising from a microdeletion at chromosome band 7q11.23 that results in a hemizygous condition for a number of genes. Within this region we completely characterized 200 kilobases (kb) of genomic DNA sequence containing the genes LIMKI, WBSCRl and RFC2. The orthologous region on mouse chromosome 5 was sequenced and compared to 7q11.23. A previously unidentified gene, ( WBSCRS), was found in the region commonly deleted in WBS patients. Expression patterns and alternative splice variants of WBSCRS and WBSCRl were determined. Chromosome 7q22 has been the focus of many cytogenetic and molecular studies aimed at delineating regions commonly deleted in myeloid leukemias and myelodysplastic syndromes. We have compared a gene dense, G-C rich sub-region of 7q22 to the orthologous region on mouse chromosome 5. A physical map of 640 kb of genomic DNA from mouse chromosome 5 was derived from a series of overlapping bacterial artificial chromosomes (BAC). A 296 kb segment from the physical map, spanning from acetylcholine esterase (Ache) to transferrin receptor 2 (Tfr2), was compared to 267 kb of human sequence. A conserved linkage of twelve genes including arsenite resistance 2 (Ars2) and zonadhesin (Zan) was identified. The paired immunoglobulin-like receptor locus (PILR) at 7q22 shares homology with 7q11.23 and contains the inhibiting PILRA and activating PILRB receptors. These receptors are expressed in myeloid cells and have been established as novel regulators of innate immunity. Expression analysis of the human PILRB gene revealed it has been dramatically affected by the insertion of a segmental duplication that is paralogous to the sequence flanking the WBS critical region. Sequencing and analysis of the orthologous region in the mouse genome revealed a previously unreported paired immunoglobulin like receptor gene (Pilrb2). An evolutionary analysis of the PILR locus in six mammalian genomes revealed that this locus is dynamically evolving by means of gene duplication, insertion, mutation and conversion. Ars2 is a novel gene that is present in a diverse number of eukaryotic organisms and is essential for development in Danio rerio and Arabidopsis thaliana. To address the role of Ars2 in mammals, we characterized its expression in mouse and human tissues and implemented a gene targeting strategy to create a null allele in the mouse genome. Ars2 was found to be transcribed throughout development and was expressed ubiquitously in mouse and human tissues. The Ars2 protein localized to the nucleus. Ars2 null mice have an early embryonic lethal phenotype establishing that Ars2 is necessary for the development of diverse multi-cellular organisms. Zonadhesin (ZAN) is the only mammalian sperm protein that has been demonstrated to bind to intact zona pellucida of the… Advisors/Committee Members: Koop, Benjamin F. (supervisor).

Subjects/Keywords: Human chromosomes; Chromosomes

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APA (6^th Edition):

Wilson, M. D. (2008). Comparative and functional genomic analysis of a gene dense region at chromosome 7q22. (Thesis). University of Victoria. Retrieved from http://hdl.handle.net/1828/643

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wilson, Michael Davies. “Comparative and functional genomic analysis of a gene dense region at chromosome 7q22.” 2008. Thesis, University of Victoria. Accessed March 07, 2021. http://hdl.handle.net/1828/643.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wilson, Michael Davies. “Comparative and functional genomic analysis of a gene dense region at chromosome 7q22.” 2008. Web. 07 Mar 2021.

Vancouver:

Wilson MD. Comparative and functional genomic analysis of a gene dense region at chromosome 7q22. [Internet] [Thesis]. University of Victoria; 2008. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1828/643.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wilson MD. Comparative and functional genomic analysis of a gene dense region at chromosome 7q22. [Thesis]. University of Victoria; 2008. Available from: http://hdl.handle.net/1828/643

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

17. BIRHANU, KUMBI. CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA .

Degree: 2012, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/402

► Chromosomes of six Vernonia species of the family Asteraceae collected from central part of Ethiopia were studied. The chromosomes were prepared from actively growing root… (more)

Subjects/Keywords: Chromosomes; Karyotype; Vernonia

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APA (6^th Edition):

BIRHANU, K. (2012). CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/402

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

BIRHANU, KUMBI. “CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA .” 2012. Thesis, Addis Ababa University. Accessed March 07, 2021. http://etd.aau.edu.et/dspace/handle/123456789/402.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

BIRHANU, KUMBI. “CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA .” 2012. Web. 07 Mar 2021.

Vancouver:

BIRHANU K. CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA . [Internet] [Thesis]. Addis Ababa University; 2012. [cited 2021 Mar 07]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/402.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

BIRHANU K. CHROMOSOME STUDY OF SIX VERNONIA SPECIES (ASTERACEAE) FROM CENTRAL ETHIOPIA . [Thesis]. Addis Ababa University; 2012. Available from: http://etd.aau.edu.et/dspace/handle/123456789/402

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Tasmania

18. McIntosh, Alastair John. Studies on the sex chromosomes of animals.

Degree: 1952, University of Tasmania

URL: https://eprints.utas.edu.au/20233/1/whole_McIntoshAlastairJohn1952_thesis.pdf

► Meiosis in male spiders is distinguished by the multiple. sex chromosome mechanism whereby usually two or three X chromosomes move jointly to one pole at… (more)

Subjects/Keywords: Sex chromosomes

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APA (6^th Edition):

McIntosh, A. J. (1952). Studies on the sex chromosomes of animals. (Thesis). University of Tasmania. Retrieved from https://eprints.utas.edu.au/20233/1/whole_McIntoshAlastairJohn1952_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McIntosh, Alastair John. “Studies on the sex chromosomes of animals.” 1952. Thesis, University of Tasmania. Accessed March 07, 2021. https://eprints.utas.edu.au/20233/1/whole_McIntoshAlastairJohn1952_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

McIntosh, Alastair John. “Studies on the sex chromosomes of animals.” 1952. Web. 07 Mar 2021.

Vancouver:

McIntosh AJ. Studies on the sex chromosomes of animals. [Internet] [Thesis]. University of Tasmania; 1952. [cited 2021 Mar 07]. Available from: https://eprints.utas.edu.au/20233/1/whole_McIntoshAlastairJohn1952_thesis.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McIntosh AJ. Studies on the sex chromosomes of animals. [Thesis]. University of Tasmania; 1952. Available from: https://eprints.utas.edu.au/20233/1/whole_McIntoshAlastairJohn1952_thesis.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université Laval

19. Trempe, Frédéric. Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique.

Degree: 2013, Université Laval

URL: http://hdl.handle.net/20.500.11794/23947

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L’herpèsvirus humain de type 6 (HHV-6) infecte les enfants en bas âge et sa prévalence est estimée à près de 95% dans la population mondiale.… (more)

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L’herpèsvirus humain de type 6 (HHV-6) infecte les enfants en bas âge et sa prévalence est estimée à près de 95% dans la population mondiale. Ce virus se distingue des autres membres de la famille des herperviridae par sa capacité à s’intégrer aux chromosomes cellulaires. On estime qu’environ 1% de la population mondiale serait porteuse d’une copie du génome du HHV-6 par cellule (52, 73, 100, 119, 131). Le mécanisme de cette intégration est toujours inconnu. Nous pensons que la protéine U94 du HHV-6 joue un rôle important dans l'intégration chromosomique du génome viral. Elle serait nécessaire à l'éxécution d'une recombinaison homologue entre les séquences télomériques cellulaires et virales (motif TTAGGG). U94 a une homologie de séquence de 24% avec la protéine Rep68 responsable de l'intégration du génome de l’adeno-associated virus 2 (AAV-2) au chromosome 19 (123). Pour ce faire, quatre activités intrinsèques à la protéine Rep68 lui sont nécessaires : la liaison à l'ADN simple et double brin, l'ATPase, l'hélicase et l'endonucléase (54, 97). Le but de ce projet de recherche était de caractériser les activitités biochimiques de la protéine U94. Tout d’abord, nous avons démontré que la protéine U94A est localisée au noyau en accord avec les résultats obtenus par le laboratoire du Dr. Mori (87). Pour réaliser nos études, nous avons exprimé et purifié U94 chez E. coli en fusion avec la protéine maltose-binding protein (MPB). Nos résultats démontrent que les protéines MBP-U94A et MBP-U94B sont capables de lier préférentiellement l'ADN simple brin avec un motif CCCTAA (complément du motif télomérique TTAGGG). L’essai de liaison sur le Proteon™ XPR36 démontre également que la protéine MBP-U94B lie un ADN double brin ayant le motif télomérique cellulaire. Nos résultats nous ont amenés à vérifier si l'ARN de la télomérase, qui contient un motif CCCTAA, pouvait aussi être lié par les protéines MBP-U94A et MBP-U94B. Les résultats obtenus indiquent que MBP-U94 ne lie pas l'ARN, ni la séquence équivalente en ADN ce qui suggère que la liaison de U94 requiert plus d’une répétition du motif CCCTAA. En se basant sur des études de mutagenèse réalisées sur la protéine Rep68 (128, 129), nous avons générés des mutants U94A et U94B. Les résultats démontrent que la mutation K395A affecte négativement la capacité de liaison à l’ADN de U94. Les essais d'ATPase indiquent que MBP-U94A et MBP-U94B hydrolysent l'ATP en ADP et AMP en présence d'un ADN simple brin ou d’un ADN double brin. Divers mutants des activités d’ATPase/Hélicase et d’endonucléase présumées furent générés et devront être caractérisés. Ces résultats suggèrent que U94 possède les activités biochimiques nécessaires à l'intégration du génome viral aux chromosomes cellulaires.

Human herpesvirus 6 infects young children with an estimated prevalence of 95% in the world population. It differs from the other members of the herperviridae family by its capacity to integrate cell's chromosomes. It is estimated that approximately 1% of the world population carries a copy of the HHV-6…

Advisors/Committee Members: Flamand, Louis, Morissette, Guillaume.

Subjects/Keywords: Herpèsvirus humain 6; Protéines; Chromosomes

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APA (6^th Edition):

Trempe, F. (2013). Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique. (Thesis). Université Laval. Retrieved from http://hdl.handle.net/20.500.11794/23947

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Trempe, Frédéric. “Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique.” 2013. Thesis, Université Laval. Accessed March 07, 2021. http://hdl.handle.net/20.500.11794/23947.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Trempe, Frédéric. “Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique.” 2013. Web. 07 Mar 2021.

Vancouver:

Trempe F. Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique. [Internet] [Thesis]. Université Laval; 2013. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/20.500.11794/23947.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Trempe F. Étude du rôle de la protéine U94 de l'herpèsvirus humain de type 6 dans le processus de l'intégration chromosomique. [Thesis]. Université Laval; 2013. Available from: http://hdl.handle.net/20.500.11794/23947

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Axton, John Myles. Genetic and molecular analysis of mitotic chromosome condensation in Drosophila.

Degree: PhD, 1990, Imperial College London

URL: http://hdl.handle.net/10044/1/47760

Subjects/Keywords: 572.8; Chromosomes

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APA (6^th Edition):

Axton, J. M. (1990). Genetic and molecular analysis of mitotic chromosome condensation in Drosophila. (Doctoral Dissertation). Imperial College London. Retrieved from http://hdl.handle.net/10044/1/47760

Chicago Manual of Style (16^th Edition):

Axton, John Myles. “Genetic and molecular analysis of mitotic chromosome condensation in Drosophila.” 1990. Doctoral Dissertation, Imperial College London. Accessed March 07, 2021. http://hdl.handle.net/10044/1/47760.

MLA Handbook (7^th Edition):

Axton, John Myles. “Genetic and molecular analysis of mitotic chromosome condensation in Drosophila.” 1990. Web. 07 Mar 2021.

Vancouver:

Axton JM. Genetic and molecular analysis of mitotic chromosome condensation in Drosophila. [Internet] [Doctoral dissertation]. Imperial College London; 1990. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10044/1/47760.

Council of Science Editors:

Axton JM. Genetic and molecular analysis of mitotic chromosome condensation in Drosophila. [Doctoral Dissertation]. Imperial College London; 1990. Available from: http://hdl.handle.net/10044/1/47760

University of Bradford

21. Al-Shammari, Mohamad Hilal. Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers.

Degree: PhD, 2013, University of Bradford

URL: http://hdl.handle.net/10454/6318

► Biological and environmental factors contribute collectively to the development of human cancers. The primary focus of this research project was to investigate the impact of… (more)

▼ Biological and environmental factors contribute collectively to the development of human cancers. The primary focus of this research project was to investigate the impact of germline gene mutations, as a significant biological factor, on 29 major primary human cancers. For this I obtained data from multiple databases, including the Genetic Association Database (GAD), Sanger database (COSMIC), HGMD database, OMIM data and PubMed literature. Using the Extraction Transform and Load (ETL) process, 424 genes were obtained with 8,879 cancer mutation records. By integrating these gene mutation records a Human Cancer Map (HCM) was constructed, from which several sub-maps were derived based on particular mutation classes. Furthermore, a Protein-Protein Interaction Map (PPIM) was constructed based on the encoded proteins of the 424 gene set. Several key questions were addressed using the HCM and its sub-maps including the following: (i) Are individual groups of primary cancers associated with specific subset of genes (within the 424 full set)? (ii) Are groups of primary cancers associated with particular mutation classes? (iii) If both questions prove to be true, are groups of cancers associated with particular mutation class of target genes? This project also explored whether a corresponding Protein-Protein Interaction Map, derived from the Missense/Non-sense Mutation portion of the HCM gene set, would provide further information on gene associations between primary cancers in terms of the consequent identical amino acid changes involved. Results showed that: (1) closely-connected human cancers in the HCM exhibited a strong association with a particular mutation class; (2) Missense /Nonsense and Regulatory mutations played a central role in connecting cancers (i.e. via primary nodes) and so significantly influenced the construction of the HCM; (3) Genes with Missense/Nonsense and Regulatory mutations tended to be involved in cancer-associated pathways; (4) Using the kappa test to measure the extent of agreement between two connected primary cancers in the sub-HCMs, BRCA1, BRCA2, PALB2, MSH2, MSH6, MLH1, CDKN2A, and TP53 showed highest agreement for 5 of 10 mutation classes; (5) From the PIPM, it was evident that BRCA1, MSH6, BARD1, TP53, MSH2 and CHEK2 proteins best connected Breast, Ovarian, Prostate and Bowel primary cancers, and so the latter could represent 'driver proteins' for these cancers. In summary, this project has approached the analysis of gene involvement in human primary cancers from the starting position of the mutation class that harbours the specific gene mutation. Together with their downstream resultant alterations in the associated proteins, this analysis can provide insights into the relatedness of primary human cancers and their potential gene hierarchies. These data may therefore help us to understand more fully the etiology, diagnosis and potentially personalized treatments for cancer.

Subjects/Keywords: 616.99; Cancer; Mutation; Chromosomes; Pathways

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APA (6^th Edition):

Al-Shammari, M. H. (2013). Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers. (Doctoral Dissertation). University of Bradford. Retrieved from http://hdl.handle.net/10454/6318

Chicago Manual of Style (16^th Edition):

Al-Shammari, Mohamad Hilal. “Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers.” 2013. Doctoral Dissertation, University of Bradford. Accessed March 07, 2021. http://hdl.handle.net/10454/6318.

MLA Handbook (7^th Edition):

Al-Shammari, Mohamad Hilal. “Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers.” 2013. Web. 07 Mar 2021.

Vancouver:

Al-Shammari MH. Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers. [Internet] [Doctoral dissertation]. University of Bradford; 2013. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10454/6318.

Council of Science Editors:

Al-Shammari MH. Integrated data analytics of germline mutation classes in human cancers : an integrated bioinformatics analysis to investigate associations between germline mutation classes and human cancers. [Doctoral Dissertation]. University of Bradford; 2013. Available from: http://hdl.handle.net/10454/6318

University of Dundee

22. Klotz-Noack, Kathleen. Consequences of partial chromosome re-replication in mammalian cells.

Degree: PhD, 2013, University of Dundee

URL: https://discovery.dundee.ac.uk/en/studentTheses/11c776ae-8192-4993-b317-7eb27d8dbf49 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578910

► To prevent re-replication of DNA in a single cell cycle, the licensing of replication origins by Mcm2-7 is prevented during S and G2 phases. Metazoans… (more)

Subjects/Keywords: 570; Chromosomes; Mammals; Cells

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APA (6^th Edition):

Klotz-Noack, K. (2013). Consequences of partial chromosome re-replication in mammalian cells. (Doctoral Dissertation). University of Dundee. Retrieved from https://discovery.dundee.ac.uk/en/studentTheses/11c776ae-8192-4993-b317-7eb27d8dbf49 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578910

Chicago Manual of Style (16^th Edition):

Klotz-Noack, Kathleen. “Consequences of partial chromosome re-replication in mammalian cells.” 2013. Doctoral Dissertation, University of Dundee. Accessed March 07, 2021. https://discovery.dundee.ac.uk/en/studentTheses/11c776ae-8192-4993-b317-7eb27d8dbf49 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578910.

MLA Handbook (7^th Edition):

Klotz-Noack, Kathleen. “Consequences of partial chromosome re-replication in mammalian cells.” 2013. Web. 07 Mar 2021.

Vancouver:

Klotz-Noack K. Consequences of partial chromosome re-replication in mammalian cells. [Internet] [Doctoral dissertation]. University of Dundee; 2013. [cited 2021 Mar 07]. Available from: https://discovery.dundee.ac.uk/en/studentTheses/11c776ae-8192-4993-b317-7eb27d8dbf49 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578910.

Council of Science Editors:

Klotz-Noack K. Consequences of partial chromosome re-replication in mammalian cells. [Doctoral Dissertation]. University of Dundee; 2013. Available from: https://discovery.dundee.ac.uk/en/studentTheses/11c776ae-8192-4993-b317-7eb27d8dbf49 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578910

Hong Kong University of Science and Technology

23. Leung, Win Kin. Dinoflagellate viral nucleoproteins.

Degree: 2014, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-86330 ; https://doi.org/10.14711/thesis-b1334228 ; http://repository.ust.hk/ir/bitstream/1783.1-86330/1/th_redirect.html

► Dinoflagellates are an exceptional group of unicellular microorganisms that exhibit a novel perspective in chromatin biology as they bear a number of unique characteristics. Their… (more)

Subjects/Keywords: Dinoflagellates ; Genetics ; Chromosomes ; Analysis ; Nucleoproteins

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APA (6^th Edition):

Leung, W. K. (2014). Dinoflagellate viral nucleoproteins. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-86330 ; https://doi.org/10.14711/thesis-b1334228 ; http://repository.ust.hk/ir/bitstream/1783.1-86330/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Leung, Win Kin. “Dinoflagellate viral nucleoproteins.” 2014. Thesis, Hong Kong University of Science and Technology. Accessed March 07, 2021. http://repository.ust.hk/ir/Record/1783.1-86330 ; https://doi.org/10.14711/thesis-b1334228 ; http://repository.ust.hk/ir/bitstream/1783.1-86330/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Leung, Win Kin. “Dinoflagellate viral nucleoproteins.” 2014. Web. 07 Mar 2021.

Vancouver:

Leung WK. Dinoflagellate viral nucleoproteins. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2014. [cited 2021 Mar 07]. Available from: http://repository.ust.hk/ir/Record/1783.1-86330 ; https://doi.org/10.14711/thesis-b1334228 ; http://repository.ust.hk/ir/bitstream/1783.1-86330/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Leung WK. Dinoflagellate viral nucleoproteins. [Thesis]. Hong Kong University of Science and Technology; 2014. Available from: http://repository.ust.hk/ir/Record/1783.1-86330 ; https://doi.org/10.14711/thesis-b1334228 ; http://repository.ust.hk/ir/bitstream/1783.1-86330/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

24. Godfrey, Otis Webster. Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes.

Degree: PhD, Department of Microbiology and Public Health, 1969, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:23519

Subjects/Keywords: Chromosomes; Salmonella

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APA (6^th Edition):

Godfrey, O. W. (1969). Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:23519

Chicago Manual of Style (16^th Edition):

Godfrey, Otis Webster. “Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes.” 1969. Doctoral Dissertation, Michigan State University. Accessed March 07, 2021. http://etd.lib.msu.edu/islandora/object/etd:23519.

MLA Handbook (7^th Edition):

Godfrey, Otis Webster. “Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes.” 1969. Web. 07 Mar 2021.

Vancouver:

Godfrey OW. Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes. [Internet] [Doctoral dissertation]. Michigan State University; 1969. [cited 2021 Mar 07]. Available from: http://etd.lib.msu.edu/islandora/object/etd:23519.

Council of Science Editors:

Godfrey OW. Chromosome transfer in salmonella pullorum mediated by f-prime factors carrying salmonella genes. [Doctoral Dissertation]. Michigan State University; 1969. Available from: http://etd.lib.msu.edu/islandora/object/etd:23519

Montana State University

25. Joppa, Leonard Robert. Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines.

Degree: PhD, College of Agriculture, 1967, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/4402

Subjects/Keywords: Wheat.; Chromosomes.

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APA (6^th Edition):

Joppa, L. R. (1967). Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines. (Doctoral Dissertation). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/4402

Chicago Manual of Style (16^th Edition):

Joppa, Leonard Robert. “Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines.” 1967. Doctoral Dissertation, Montana State University. Accessed March 07, 2021. https://scholarworks.montana.edu/xmlui/handle/1/4402.

MLA Handbook (7^th Edition):

Joppa, Leonard Robert. “Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines.” 1967. Web. 07 Mar 2021.

Vancouver:

Joppa LR. Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines. [Internet] [Doctoral dissertation]. Montana State University; 1967. [cited 2021 Mar 07]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4402.

Council of Science Editors:

Joppa LR. Chromosome segregation in a Triticum aestivum L. em. Thell. by T. durum Desf. cross and the production of D genome addition lines. [Doctoral Dissertation]. Montana State University; 1967. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4402

Montana State University

26. Collins, Don Desmond. Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana.

Degree: PhD, College of Agriculture, 1965, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/4309

Subjects/Keywords: Chromosomes.; Grasses.

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APA (6^th Edition):

Collins, D. D. (1965). Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana. (Doctoral Dissertation). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/4309

Chicago Manual of Style (16^th Edition):

Collins, Don Desmond. “Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana.” 1965. Doctoral Dissertation, Montana State University. Accessed March 07, 2021. https://scholarworks.montana.edu/xmlui/handle/1/4309.

MLA Handbook (7^th Edition):

Collins, Don Desmond. “Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana.” 1965. Web. 07 Mar 2021.

Vancouver:

Collins DD. Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana. [Internet] [Doctoral dissertation]. Montana State University; 1965. [cited 2021 Mar 07]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4309.

Council of Science Editors:

Collins DD. Ecological, biosystematic and biochemical studies of species in the genus Agropyron Gaertn. native to Montana. [Doctoral Dissertation]. Montana State University; 1965. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4309

University of Illinois – Urbana-Champaign

27. Wadlington, William H. Characterization of the sex chromosomes in spinach.

Degree: PhD, Plant Biology, 2017, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/98172

► Plant sex chromosomes have evolved from the autosomes of hermaphroditic species to maintain dioecy. The major barriers to sex chromosome characterization have been the inherent… (more)

▼ Plant sex chromosomes have evolved from the autosomes of hermaphroditic species to maintain dioecy. The major barriers to sex chromosome characterization have been the inherent difficulties of working with a non-recombining sex determining region that make sequencing and mapping the Male-Specific region of the Y chromosome (MSY) painstaking. Here we use YY spinach (Spinacia oleracea L.) to characterize the MSY and the X-specific region of the X chromosome. A screen of 395 accessions in the USDA germplasm collection found a single accession that segregates YY progeny. The YY genotype was verified by a genetic cross and a novel X-specific marker. Potential novel X-specific sequences were found by depth of coverage analysis comparing alignments of male and female sequences to an XX reference. Of the 19 candidates found by depth of coverage, only one was verified as X-specific. The marker SpoX amplifies products from XX and XY but not YY templates. Pooled genomic DNA of 16 YY individuals selected by SpoX was sequenced at 63X using PacBio. Sequence data was assembled into an 823 Mbp assembly using CANU so the YY assembly could be compared to a 911 Mbp XX assembly. Seven genes that were non-repetitive sequences were found on a 1.14 X-specific contig from the XX assembly, and were queried by BLAST to the YY assembly to find their MSY homologs, which totaled 427 kb of novel Y chromosome sequence. On the Y contigs, the percentage uncovered by female k-mers decreased from 9.5% to 0.6% between positions 65.8 Mbp and 66.7 Mbp on the X chromosome, indicating that it is the location of one of the boundaries of the non-recombining region. The discovery of an accession which reliably segregates YY plants makes for unprecedented opportunity to study X and Y chromosomes in spinach. By comparing YY and XX genomes, the genomic basis of X and Y chromosome differentiation and evolution that gave rise to dioecy can be elucidated. Advisors/Committee Members: Ming, Ray (advisor), Ming, Ray (Committee Chair), Heath, Katy (committee member), Downie, Stephen (committee member), Tranel, Pat (committee member), Hanzawa, Yoshie (committee member).

Subjects/Keywords: Spinach; Sex chromosomes; Dioecy

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APA (6^th Edition):

Wadlington, W. H. (2017). Characterization of the sex chromosomes in spinach. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/98172

Chicago Manual of Style (16^th Edition):

Wadlington, William H. “Characterization of the sex chromosomes in spinach.” 2017. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed March 07, 2021. http://hdl.handle.net/2142/98172.

MLA Handbook (7^th Edition):

Wadlington, William H. “Characterization of the sex chromosomes in spinach.” 2017. Web. 07 Mar 2021.

Vancouver:

Wadlington WH. Characterization of the sex chromosomes in spinach. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2142/98172.

Council of Science Editors:

Wadlington WH. Characterization of the sex chromosomes in spinach. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2017. Available from: http://hdl.handle.net/2142/98172

University of Arizona

28. Zukowski, Mark M. Sister chromatid exchange rates in human twins .

Degree: 1978, University of Arizona

URL: http://hdl.handle.net/10150/566676

Subjects/Keywords: Human chromosomes.

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APA (6^th Edition):

Zukowski, M. M. (1978). Sister chromatid exchange rates in human twins . (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/566676

Chicago Manual of Style (16^th Edition):

Zukowski, Mark M. “Sister chromatid exchange rates in human twins .” 1978. Masters Thesis, University of Arizona. Accessed March 07, 2021. http://hdl.handle.net/10150/566676.

MLA Handbook (7^th Edition):

Zukowski, Mark M. “Sister chromatid exchange rates in human twins .” 1978. Web. 07 Mar 2021.

Vancouver:

Zukowski MM. Sister chromatid exchange rates in human twins . [Internet] [Masters thesis]. University of Arizona; 1978. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10150/566676.

Council of Science Editors:

Zukowski MM. Sister chromatid exchange rates in human twins . [Masters Thesis]. University of Arizona; 1978. Available from: http://hdl.handle.net/10150/566676

University of Arizona

29. Ward, Bernard Lloyd, 1942-. Salivary gland chromosome analyses of Drosophila pachea and related species .

Degree: 1969, University of Arizona

URL: http://hdl.handle.net/10150/347699

Subjects/Keywords: Chromosomes.; Drosophila.

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APA (6^th Edition):

Ward, Bernard Lloyd, 1. (1969). Salivary gland chromosome analyses of Drosophila pachea and related species . (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/347699

Chicago Manual of Style (16^th Edition):

Ward, Bernard Lloyd, 1942-. “Salivary gland chromosome analyses of Drosophila pachea and related species .” 1969. Masters Thesis, University of Arizona. Accessed March 07, 2021. http://hdl.handle.net/10150/347699.

MLA Handbook (7^th Edition):

Ward, Bernard Lloyd, 1942-. “Salivary gland chromosome analyses of Drosophila pachea and related species .” 1969. Web. 07 Mar 2021.

Vancouver:

Ward, Bernard Lloyd 1. Salivary gland chromosome analyses of Drosophila pachea and related species . [Internet] [Masters thesis]. University of Arizona; 1969. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10150/347699.

Council of Science Editors:

Ward, Bernard Lloyd 1. Salivary gland chromosome analyses of Drosophila pachea and related species . [Masters Thesis]. University of Arizona; 1969. Available from: http://hdl.handle.net/10150/347699

Georgia Tech

30. Allgood, Jackson Lee. A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw).

Degree: MS, Applied biology, 1971, Georgia Tech

URL: http://hdl.handle.net/1853/25379

Subjects/Keywords: Hamsters; Chromosomes

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APA (6^th Edition):

Allgood, J. L. (1971). A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw). (Masters Thesis). Georgia Tech. Retrieved from http://hdl.handle.net/1853/25379

Chicago Manual of Style (16^th Edition):

Allgood, Jackson Lee. “A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw).” 1971. Masters Thesis, Georgia Tech. Accessed March 07, 2021. http://hdl.handle.net/1853/25379.

MLA Handbook (7^th Edition):

Allgood, Jackson Lee. “A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw).” 1971. Web. 07 Mar 2021.

Vancouver:

Allgood JL. A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw). [Internet] [Masters thesis]. Georgia Tech; 1971. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1853/25379.

Council of Science Editors:

Allgood JL. A determination of the frequency of aneuploidy in Chinese hamsters (Cricetulus griseus Milne-Edw). [Masters Thesis]. Georgia Tech; 1971. Available from: http://hdl.handle.net/1853/25379

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