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You searched for subject:(Chemosterilant). Showing records 1 – 2 of 2 total matches.

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1. Thomas, Lali. Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -.

Degree: Zoology, 1991, INFLIBNET

None

Bibliography p.149-176

Advisors/Committee Members: Sahai, Y N.

Subjects/Keywords: Chemosterilant; Pictus; Poekilocerus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Thomas, L. (1991). Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -. (Thesis). INFLIBNET. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/41082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Thomas, Lali. “Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -.” 1991. Thesis, INFLIBNET. Accessed September 18, 2020. http://shodhganga.inflibnet.ac.in/handle/10603/41082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Thomas, Lali. “Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -.” 1991. Web. 18 Sep 2020.

Vancouver:

Thomas L. Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -. [Internet] [Thesis]. INFLIBNET; 1991. [cited 2020 Sep 18]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/41082.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Thomas L. Chemosterilant induced changes in the reproductive organs of poekilocerus pictus fabr; -. [Thesis]. INFLIBNET; 1991. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/41082

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Lincoln University

2. Burd, Anna Mae. In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent.

Degree: 2014, Lincoln University

In New Zealand (NZ), the brushtail possum (Trichosurus vulpecula) poses a major threat to native flora and fauna and it is the main wildlife vector for bovine tuberculosis. Primary control utilizes lethal means but these methods have limited efficacy long-term and are associated with environmental impact concerns. Fertility control has become more popular as it is potentially more effective, sustainable and humane. The industrial chemical, 4-vinylcyclohexene diepoxide (VCD) may serve as an ideal chemosterilant candidate for investigation. Oral gavage studies have shown that VCD reduces the pool of non-regenerating immature ovarian follicles in rodents, resulting in premature ovarian failure and sterility. The first objective of these studies was to examine the effects of orally administered VCD on female possum ovarian follicle populations. Orally delivered VCD had no effect on the primordial follicles of adult female possums and two formulations aimed at improving VCD uptake and efficacy did not change this outcome. The second objective examined the uptake and metabolism of orally administered VCD in female possums and rats in vivo. VCD concentration in the blood of rats was significantly greater than in possums while concentrations of VCD in the stomach were comparable between species. VCD dosing did not alter pH of stomach contents of possums while that of rats was increased and sustained for 6 hours. VCD-induced reductions in ovarian and liver glutathione levels were observed in the rat with no effects in the possum. It was determined that the highly acidic environment of the stomach of possums poses an initial barrier for orally delivered VCD. Without sufficient quantities of VCD reaching the liver and ovaries of possums, it was not possible to compare species differences in metabolism in vivo. The third objective examined the fate of VCD when exposed to acidic environments and stomach contents and the effects of VCD on liver metabolism in vitro in possums and rats. VCD hydrolysis in stomach contents was slower in possums compared with rats suggesting that possum stomach contents are able to retain VCD longer, thus potentially modulating VCD toxicity. GSH levels in possum liver tissue were less affected when incubated with VCD compared with rats, suggesting an increased detoxifying capacity of possums. Preliminary data on the ability of possum liver microsomes to convert VCD’s parent compound, 4-vinycyclohexene, to VCD corroborated the GSH findings. Collectively, these findings suggest that VCD may not be suitable for possum fertility control when delivered orally in a raw unprotected chemical state. Encapsulation of VCD with an additional active compound, triptolide, is being examined as a novel chemosterilant (ContraPest®, SenesTech®, Flagstaff, Arizona). The fourth objective examined ContraPest® efficacy in wild-caught female Norway rats. The ovarian primordial follicle pools of ContraPest®-consuming rats were reduced compared with controls. The proposed protection of the active components within ContraPest®…

Subjects/Keywords: Brushtail possum; Norway rat; fertility control; pest control; chemosterilant; bait; 4-vinylcyclohexene diepoxide; ovary; ovarian follicle; stomach pH; glutathione; metabolism; 06 Biological Sciences; 070201 Animal Breeding

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Burd, A. M. (2014). In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent. (Thesis). Lincoln University. Retrieved from http://hdl.handle.net/10182/5951

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Burd, Anna Mae. “In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent.” 2014. Thesis, Lincoln University. Accessed September 18, 2020. http://hdl.handle.net/10182/5951.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Burd, Anna Mae. “In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent.” 2014. Web. 18 Sep 2020.

Vancouver:

Burd AM. In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent. [Internet] [Thesis]. Lincoln University; 2014. [cited 2020 Sep 18]. Available from: http://hdl.handle.net/10182/5951.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Burd AM. In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent. [Thesis]. Lincoln University; 2014. Available from: http://hdl.handle.net/10182/5951

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.