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You searched for subject:(Chemical complementation). Showing records 1 – 4 of 4 total matches.

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1. Shaffer, Hally A. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.

Degree: PhD, Chemistry and Biochemistry, 2011, Georgia Tech

 Nuclear receptors are ligand-activated transcription factors that play significant roles in various biological processes within the body, such as cell development, hormone metabolism, reproduction, and… (more)

Subjects/Keywords: Nuclear receptors; Chemical complementation; Negative chemical complementation; Yeast-two hybrid selection; Pregnane X receptor; Estrogen receptor; Pregnane; Protein engineering; Nuclear receptors (Biochemistry); Transcription factors; Yeast Genetics

Complementation 12 1.4 Applications of Chemical Complemenation 15 1.4.1 Drug Discovery 15 1.4.2… …Promiscuous Activity of PXR 27 2.3 PXR in Chemical Complementation 32 2.4 PXR Library for… …Chemical Complementation 41 2.5 PXR in HEK293T Mammalian Cells 50 2.6 Summary and Future Work… …Complementation 99 ix 4.3.2 hERα Variants in Chemical Complementation 103 4.3.3 Random Mutagenesis… …COMPLEMENTATION WITH ANTAGONISTS 159 6.1 Genetic Selection and Negative Chemical Complementation 159… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Shaffer, H. A. (2011). Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/39620

Chicago Manual of Style (16th Edition):

Shaffer, Hally A. “Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.” 2011. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/39620.

MLA Handbook (7th Edition):

Shaffer, Hally A. “Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation.” 2011. Web. 27 Nov 2020.

Vancouver:

Shaffer HA. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. [Internet] [Doctoral dissertation]. Georgia Tech; 2011. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/39620.

Council of Science Editors:

Shaffer HA. Engineering the pregnane X receptor and estrogen receptor alpha to bind novel small molecules using negative chemical complementation. [Doctoral Dissertation]. Georgia Tech; 2011. Available from: http://hdl.handle.net/1853/39620


INP Toulouse

2. Bacha, Nafees. Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach).

Degree: Docteur es, Microbiologie et biocatalyse industrielles, 2009, INP Toulouse

Aspergillus westerdijkiaem qui est récemment démembré d'A. ochraceus est un producteur principal de plusieurs composés de type polycétone d'importance économique. Ces composés incluent l’ochratoxin A,… (more)

Subjects/Keywords: Aspergillus westerdijkiae; Polycétone synthase gènes; Caractérisation génétique; Genome walking; Transformation; Complémentation chimique; Ochratoxine A; Acide penicillique; Aspyrone; Acide 6-methylsalicylique; Isoasperlactone; Asperlactone; Aspergillus westerdijkiae; Polyketide synthase genes; Genetic characterization; Genome calking; Transformation; Chemical complementation; Ochratoxin A; Penicillic acid; Aspyrone; 6-methylsalicylic acid; Isoasperlactone; Asperlactone

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Bacha, N. (2009). Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach). (Doctoral Dissertation). INP Toulouse. Retrieved from http://www.theses.fr/2009INPT004A

Chicago Manual of Style (16th Edition):

Bacha, Nafees. “Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach).” 2009. Doctoral Dissertation, INP Toulouse. Accessed November 27, 2020. http://www.theses.fr/2009INPT004A.

MLA Handbook (7th Edition):

Bacha, Nafees. “Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach).” 2009. Web. 27 Nov 2020.

Vancouver:

Bacha N. Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach). [Internet] [Doctoral dissertation]. INP Toulouse; 2009. [cited 2020 Nov 27]. Available from: http://www.theses.fr/2009INPT004A.

Council of Science Editors:

Bacha N. Caractérisation des polycétones synthases intervenant dans la biosynthèse d’ochratoxine A, d’acide pénicillique, d’asperlactone et d’isoasperlactone chez aspergillus westerdijkiae : Caracterization of the polyketide synthases involved in biosynthesis of ochratoxin A, penicillic acid, asperlactone and isoasperlactone in aspergillus westerdijkiae (a molecular approach). [Doctoral Dissertation]. INP Toulouse; 2009. Available from: http://www.theses.fr/2009INPT004A

3. Johnson, Kenyetta Alicia. Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery.

Degree: PhD, Chemistry and Biochemistry, 2009, Georgia Tech

 Nuclear receptors (NRs) are modular ligand-activated transcription factors that control a broad range of physiological processes by regulating the expression of essential genes involved in… (more)

Subjects/Keywords: Protein engineering; Nuclear receptor; Chemical complementation; Drug discovery; Nuclear receptors (Biochemistry); Developmental pharmacology; Protein engineering; Yeast Genetics

Chemical Complementation Bacterial Two-Hybrid Systems Literature Cited CHAPTER 3 23 23 25 30 35… …41 BACTERIAL CHEMICAL COMPLEMENTATION: ELIMINATING BACKGROUND 47 3.3 Bacterial Chemical… …Complementation: Bacteria vs. Yeast 3.2 Developing Bacterial Chemical Complementation 3.3 Results of… …Eliminating Bacterial Chemical Complementation Background 3.3.1 Effects of Expression Vectors on… …63 67 CHAPTER 4 BACTERIAL CHEMICAL COMPLEMENTATION: LIGAND DEPENDENT ACTIVATION 70 4.1… 

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Johnson, K. A. (2009). Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/29652

Chicago Manual of Style (16th Edition):

Johnson, Kenyetta Alicia. “Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery.” 2009. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/29652.

MLA Handbook (7th Edition):

Johnson, Kenyetta Alicia. “Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery.” 2009. Web. 27 Nov 2020.

Vancouver:

Johnson KA. Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery. [Internet] [Doctoral dissertation]. Georgia Tech; 2009. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/29652.

Council of Science Editors:

Johnson KA. Extending chemical complemenation to bacteria and furthering nuclear receptor based protein engineering and drug discovery. [Doctoral Dissertation]. Georgia Tech; 2009. Available from: http://hdl.handle.net/1853/29652


Georgia Tech

4. Schwimmer, Lauren J. Engineering ligand-receptor pairs for small molecule control of transcription.

Degree: PhD, Chemistry and Biochemistry, 2005, Georgia Tech

 Creating receptors for control of transcription with arbitrary small molecules has widespread applications including gene therapy, biosensors, and enzyme engineering. Using the combination of high… (more)

Subjects/Keywords: Chemical complementation; Ligand-receptor pair; Protein engineering; Retinoid X receptor; Nuclear receptor; Codon randomized libraries; Transcription factors; Protein engineering; Nuclear receptors (Biochemistry); Genetic engineering

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Schwimmer, L. J. (2005). Engineering ligand-receptor pairs for small molecule control of transcription. (Doctoral Dissertation). Georgia Tech. Retrieved from http://hdl.handle.net/1853/11651

Chicago Manual of Style (16th Edition):

Schwimmer, Lauren J. “Engineering ligand-receptor pairs for small molecule control of transcription.” 2005. Doctoral Dissertation, Georgia Tech. Accessed November 27, 2020. http://hdl.handle.net/1853/11651.

MLA Handbook (7th Edition):

Schwimmer, Lauren J. “Engineering ligand-receptor pairs for small molecule control of transcription.” 2005. Web. 27 Nov 2020.

Vancouver:

Schwimmer LJ. Engineering ligand-receptor pairs for small molecule control of transcription. [Internet] [Doctoral dissertation]. Georgia Tech; 2005. [cited 2020 Nov 27]. Available from: http://hdl.handle.net/1853/11651.

Council of Science Editors:

Schwimmer LJ. Engineering ligand-receptor pairs for small molecule control of transcription. [Doctoral Dissertation]. Georgia Tech; 2005. Available from: http://hdl.handle.net/1853/11651

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