subject:(Cells Mechanical properties Research)

1. Evans, Sarah Frances. Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies.

Degree: MSs (Engineering), Biomedical Engineering, 2012, Case Western Reserve University School of Graduate Studies

URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1331646902

► The periosteum serves as a stabilizing boundary membrane to the bone it envelopes and contains mechanosensitive progenitor cells capable of promoting new bone formation. Knowledge… (more)

Subjects/Keywords: Biomechanics; Biomedical Engineering; Biomedical Research; periosteum; mechanobiology; tissue level mechanical properties; perioisteum derived cells; permeability

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APA (6^th Edition):

Evans, S. F. (2012). Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies. (Masters Thesis). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1331646902

Chicago Manual of Style (16^th Edition):

Evans, Sarah Frances. “Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies.” 2012. Masters Thesis, Case Western Reserve University School of Graduate Studies. Accessed April 14, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1331646902.

MLA Handbook (7^th Edition):

Evans, Sarah Frances. “Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies.” 2012. Web. 14 Apr 2021.

Vancouver:

Evans SF. Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies. [Internet] [Masters thesis]. Case Western Reserve University School of Graduate Studies; 2012. [cited 2021 Apr 14]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1331646902.

Council of Science Editors:

Evans SF. Top Down and Bottom Up Approaches to Elucidating Multiscale Periosteal Mechanobiology: Tissue Level and Cell Scale Studies. [Masters Thesis]. Case Western Reserve University School of Graduate Studies; 2012. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1331646902

Columbia University

2. Mandriota, Nicola. The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy.

Degree: 2016, Columbia University

URL: https://doi.org/10.7916/D8MC9052

► The characterization of the mechanical behavior of cells has always captured the interest of scientists and, in the last decades, has been facilitated by the… (more)

Subjects/Keywords: Cells – Mechanical properties; Cells; Biomechanics; Nanotechnology; Biophysics

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APA (6^th Edition):

Mandriota, N. (2016). The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8MC9052

Chicago Manual of Style (16^th Edition):

Mandriota, Nicola. “The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy.” 2016. Doctoral Dissertation, Columbia University. Accessed April 14, 2021. https://doi.org/10.7916/D8MC9052.

MLA Handbook (7^th Edition):

Mandriota, Nicola. “The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy.” 2016. Web. 14 Apr 2021.

Vancouver:

Mandriota N. The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy. [Internet] [Doctoral dissertation]. Columbia University; 2016. [cited 2021 Apr 14]. Available from: https://doi.org/10.7916/D8MC9052.

Council of Science Editors:

Mandriota N. The relationship between intracellular forces and cellular stiffness investigated by atomic force microscopy. [Doctoral Dissertation]. Columbia University; 2016. Available from: https://doi.org/10.7916/D8MC9052

Michigan State University

3. Yang, Ruiguo. In situ sensing and modeling of molecular events at the cellular level.

Degree: 2014, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:2341

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Thesis Ph. D. Michigan State University. Electrical Engineering 2014.

We developed the Atomic Force Microscopy (AFM) based nanorobot in combination with other nanomechanical sensors for… (more)

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Thesis Ph. D. Michigan State University. Electrical Engineering 2014.

We developed the Atomic Force Microscopy (AFM) based nanorobot in combination with other nanomechanical sensors for the investigation of cell signaling pathways. The AFM nanorobotics hinge on the superior spatial resolution of AFM in imaging and extends it into the measurement of biological processes and manipulation of biological matters. A multiple input single output control system was designed and implemented to solve the issues of nanomanipulation of biological materials, feedback, response frequency and nonlinearity. The AFM nanorobotic system therefore provide the human-directed position, velocity and force control with high frequency feedback, and more importantly it can feed the operator with the real-time imaging of manipulation result from the fast-imaging based local scanning. The use of the system has taken the study of cellular process at the molecular scale into a new level.The cellular response to the physiological conditions can be significantly manifested in cellular mechanics. Dynamic mechanical property has been regarded as biomarkers, sometimes even regulators of the signaling and physiological processes, thus the name mechanobiology. We sought to characterize the relationship between the structural dynamics and the molecular dynamics and the role of them in the regulation of cell behavior. We used the AFM nanorobotics to investigate the mechanical properties in real-time of cells that are stimulated by different chemical species. These reagents could result in similar ion channel responses but distinctive mechanical behaviors. We applied these measurement results to establish a model that describes the cellular stimulation and the mechanical property change, a ``two-hit" model that comprises the loss of cell adhesion and the initiation of cell apoptosis. The first hit was verified by functional experiments: depletion of Calcium and nanosurgery to disrupt the cellular adhesion. The second hit was tested by a labeling of apoptotic markers that were revealed by flow cytometry. The model would then be able to decipher qualitatively the molecular dynamics infolded in the regulation of cell behavior.To decipher the signaling pathway quantitatively, we employed a nanomechanical sensor at the bottom of the cell, quartz crystal microbalance with energy dissipation monitoring (QCM-D) to monitor the change at the basal area of the cell. This would provide the real time focal adhesion information and would be used in accordance with the AFM measurement data on the top of the cell to build a more complete mechanical profile during the antibody induced signaling process. We developed a model from a systematic control perspective that considers the signaling cascade at certain stimulation as the controller and the mechanical and structural interaction of the cell as the plant. We firstly derived the plant model based on QCM-D and AFM measurement processes. A signaling pathway model was built on a grey box approach where part of the…

Advisors/Committee Members: Xi, Ning, Dong, Lixin, McGough, Robert J., Wang, Donna H., Sinha, Animesh A..

Subjects/Keywords: Cellular signal transduction – Research; Cells – Mechanical properties – Research; Atomic force microscopy; Nanotechnology; Biomedical engineering – Research; Electrical engineering; Biomedical engineering; Biomechanics

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APA (6^th Edition):

Yang, R. (2014). In situ sensing and modeling of molecular events at the cellular level. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:2341

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yang, Ruiguo. “In situ sensing and modeling of molecular events at the cellular level.” 2014. Thesis, Michigan State University. Accessed April 14, 2021. http://etd.lib.msu.edu/islandora/object/etd:2341.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yang, Ruiguo. “In situ sensing and modeling of molecular events at the cellular level.” 2014. Web. 14 Apr 2021.

Vancouver:

Yang R. In situ sensing and modeling of molecular events at the cellular level. [Internet] [Thesis]. Michigan State University; 2014. [cited 2021 Apr 14]. Available from: http://etd.lib.msu.edu/islandora/object/etd:2341.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yang R. In situ sensing and modeling of molecular events at the cellular level. [Thesis]. Michigan State University; 2014. Available from: http://etd.lib.msu.edu/islandora/object/etd:2341

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Hong Kong University of Science and Technology

4. Yao, Zhanshi ECE. Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels.

Degree: 2019, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-103989 ; https://doi.org/10.14711/thesis-991012785567803412 ; http://repository.ust.hk/ir/bitstream/1783.1-103989/1/th_redirect.html

► Mechanical properties of biological cells can be utilized as an inherent, label-free biomarker to indicate the physiological and pathological changes of cells. Characterization of cell… (more)

▼ Mechanical properties of biological cells can be utilized as an inherent, label-free biomarker to indicate the physiological and pathological changes of cells. Characterization of cell deformability has been found to be useful to distinguish healthy and unhealthy cells for disease diagnosis. In this thesis, we focus on developing optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels for non-contact cell mechanical characterization. We develop an optofluidic cell stretcher based on a “tweeze-and-drag” mechanism using a periodically blocked optical tweezer in a microfluidic channel. Our stretcher enables a cell-stretching throughput of ~1.5 cells/s, which is much higher than conventional optical stretchers (~1 cell/min) and static testing techniques. We estimated the spring constant of red blood cells to be ~14.9 μN/m. We also distinguish healthy and unhealthy (glutaraldehyde-treated) cells based on their different mechanical responses. We further study optofluidic cell stretchers using two optical tweezers in a microfluidic channel, which potentially enables a higher characterization throughput and a more flexible way to induce cell deformation for mechanical characterization. We develop a beam-shaping technique for optical lattice generation by inventing the vertically embedded multimode-interference (MMI) polymer waveguides on a silicon chip. We demonstrate the generation of various two-dimensional optical lattices spanning from 4×4 to 10×10 arrays. We demonstrate that longitudinally offsetting the waveguide bottom end-face from the focused beam waist allows a simple way of tuning the effective waveguide length to satisfy the self-imaging condition for optical lattice generation. Based on the optical lattices generated by the vertically embedded MMI polymer waveguides, we demonstrate optofluidic cell stretchers in an optofluidic chip. Leveraging the parallel stretching in multiple rows of a 5×5 optical lattice, our stretcher enables a characterization throughput of ~ 6 cells/s. We also distinguish healthy and unhealthy cells (glutaraldehyde-treated) based on their different mechanical responses.

Subjects/Keywords: Cells ; Mechanical properties ; Optofluidics ; Microfluidics ; Optical tweezers

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APA (6^th Edition):

Yao, Z. E. (2019). Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-103989 ; https://doi.org/10.14711/thesis-991012785567803412 ; http://repository.ust.hk/ir/bitstream/1783.1-103989/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yao, Zhanshi ECE. “Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels.” 2019. Thesis, Hong Kong University of Science and Technology. Accessed April 14, 2021. http://repository.ust.hk/ir/Record/1783.1-103989 ; https://doi.org/10.14711/thesis-991012785567803412 ; http://repository.ust.hk/ir/bitstream/1783.1-103989/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yao, Zhanshi ECE. “Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels.” 2019. Web. 14 Apr 2021.

Vancouver:

Yao ZE. Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2019. [cited 2021 Apr 14]. Available from: http://repository.ust.hk/ir/Record/1783.1-103989 ; https://doi.org/10.14711/thesis-991012785567803412 ; http://repository.ust.hk/ir/bitstream/1783.1-103989/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yao ZE. Optofluidic cell stretchers using optical tweezers and interference patterns in microfluidic channels. [Thesis]. Hong Kong University of Science and Technology; 2019. Available from: http://repository.ust.hk/ir/Record/1783.1-103989 ; https://doi.org/10.14711/thesis-991012785567803412 ; http://repository.ust.hk/ir/bitstream/1783.1-103989/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Hong Kong University of Science and Technology

5. Huang, Xiaomin ECE. Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions.

Degree: 2018, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-95900 ; https://doi.org/10.14711/thesis-991012637367603412 ; http://repository.ust.hk/ir/bitstream/1783.1-95900/1/th_redirect.html

► Cell lysis for intracellular contents extraction is critical for biomedical sciences and clinical diagnostics. Plenty of chemical and physical cell lysis methods have been developed… (more)

Subjects/Keywords: Cells ; Mechanical properties ; Microfluidic devices ; Microtechnology

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APA (6^th Edition):

Huang, X. E. (2018). Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-95900 ; https://doi.org/10.14711/thesis-991012637367603412 ; http://repository.ust.hk/ir/bitstream/1783.1-95900/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Huang, Xiaomin ECE. “Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions.” 2018. Thesis, Hong Kong University of Science and Technology. Accessed April 14, 2021. http://repository.ust.hk/ir/Record/1783.1-95900 ; https://doi.org/10.14711/thesis-991012637367603412 ; http://repository.ust.hk/ir/bitstream/1783.1-95900/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Huang, Xiaomin ECE. “Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions.” 2018. Web. 14 Apr 2021.

Vancouver:

Huang XE. Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2018. [cited 2021 Apr 14]. Available from: http://repository.ust.hk/ir/Record/1783.1-95900 ; https://doi.org/10.14711/thesis-991012637367603412 ; http://repository.ust.hk/ir/bitstream/1783.1-95900/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Huang XE. Reagentless mechanical lysis for cell contents extraction through microfluidic constrictions. [Thesis]. Hong Kong University of Science and Technology; 2018. Available from: http://repository.ust.hk/ir/Record/1783.1-95900 ; https://doi.org/10.14711/thesis-991012637367603412 ; http://repository.ust.hk/ir/bitstream/1783.1-95900/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Hong Kong University of Science and Technology

6. Li, Jing PHYS. Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics.

Degree: 2017, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-100438 ; https://doi.org/10.14711/thesis-991012563569403412 ; http://repository.ust.hk/ir/bitstream/1783.1-100438/1/th_redirect.html

► Myosin X is the first reported myosin to form the anti-parallel dimer in myosin family. It was reported to be localized to the tips of… (more)

Subjects/Keywords: Myosin ; Magnetic tweezers ; Cells ; Mechanical properties

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APA (6^th Edition):

Li, J. P. (2017). Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-100438 ; https://doi.org/10.14711/thesis-991012563569403412 ; http://repository.ust.hk/ir/bitstream/1783.1-100438/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, Jing PHYS. “Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics.” 2017. Thesis, Hong Kong University of Science and Technology. Accessed April 14, 2021. http://repository.ust.hk/ir/Record/1783.1-100438 ; https://doi.org/10.14711/thesis-991012563569403412 ; http://repository.ust.hk/ir/bitstream/1783.1-100438/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, Jing PHYS. “Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics.” 2017. Web. 14 Apr 2021.

Vancouver:

Li JP. Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2017. [cited 2021 Apr 14]. Available from: http://repository.ust.hk/ir/Record/1783.1-100438 ; https://doi.org/10.14711/thesis-991012563569403412 ; http://repository.ust.hk/ir/bitstream/1783.1-100438/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li JP. Investigating the stepping mechanism of myosin X using single molecule tracking and building magnetic tweezers for the measurement of single cell mechanics. [Thesis]. Hong Kong University of Science and Technology; 2017. Available from: http://repository.ust.hk/ir/Record/1783.1-100438 ; https://doi.org/10.14711/thesis-991012563569403412 ; http://repository.ust.hk/ir/bitstream/1783.1-100438/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ryerson University

7. Bekah, Devesh. Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology.

Degree: 2010, Ryerson University

URL: https://digital.library.ryerson.ca/islandora/object/RULA%3A1402

► Experiments have shown that there is an increase in ultrasound backscatter from cells during cell death. Since cell scattering depends on the mechanical property variations,… (more)

Subjects/Keywords: Cells – Mechanical properties – Mathematical models; Cells – Mechanical properties – Computer simulation; Cancer cells – Proliferation; Cell physiology; Cell proliferation

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APA (6^th Edition):

Bekah, D. (2010). Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology. (Thesis). Ryerson University. Retrieved from https://digital.library.ryerson.ca/islandora/object/RULA%3A1402

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bekah, Devesh. “Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology.” 2010. Thesis, Ryerson University. Accessed April 14, 2021. https://digital.library.ryerson.ca/islandora/object/RULA%3A1402.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bekah, Devesh. “Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology.” 2010. Web. 14 Apr 2021.

Vancouver:

Bekah D. Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology. [Internet] [Thesis]. Ryerson University; 2010. [cited 2021 Apr 14]. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1402.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bekah D. Measurement of viscoelastic properties of treated and untreated cancer cells using passive microrheology. [Thesis]. Ryerson University; 2010. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1402

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

8. Hamweendo, Agripa. Design and evaluate a cellular manufacturing facility for selected copper products in Zambia .

Degree: 2011, University of Zambia

URL: http://hdl.handle.net/123456789/547

► The economic advancement of any country depends on its ability to add value (through manufacturing) to its available local raw material resources. Zambia for a… (more)

▼ The economic advancement of any country depends on its ability to add value (through manufacturing) to its available local raw material resources. Zambia for a long time has been exporting copper as a raw material and importing finished copper products. This economic situation deprives Zambia of more foreign exchange earning which is necessary for national development. It is therefore important that researches on viability of adding value to locally available raw material resources (such as copper) are encouraged to promote value addition before export. This research aims to address the problem of exporting copper as raw material without adding value to it. The research focuses on designing and evaluating a cellular manufacturing facility for adding value to selected copper products. Cellular manufacturing was chosen in this research because it has become a popular manufacturing system for medium demand and medium variety products. In addition, cellular manufacturing facilitates job design, job flow, capacity planning, utilization, machinery arrangement and modernization. The products selected in this research included: cable lugs, contact terminals, earth rods, neutral blocks, copper washers, copper connectors, top plugs and sockets.A market survey was conducted to identify and select the copper products. The parts from the selected copper products were grouped into part families using poly-code classification system. Production Flow Analysis was applied to identify the process engineering and the required machinery. To design the cells (to form the Part-Machine Clusters), simultaneous part family formation and machine grouping solution strategy i.e. the Ranking Order Clustering Algorithm was used. Cellular layout and evaluation processes followed the cell design stage. Cell evaluation involved cell balancing, cost, and benefit analysis. To balance the cells, the Killbridge and Wester method was used.Two (2) linked cells were formed and designed. The cell balance efficiencies were 94.2% and 88.3% indicating good capacity utilization. The cost benefit analysis was done to appraise the facility. The calculated amount of copper cathodes required per week was 3.9591 tonnes which cost US 7,773.74. If copper was to be supplied in ready-madeform,the cost per week would be US 85,083. This implies that a tonne of copper when processed to primary product would cost US 21,490.09 (330% of value of copper cathode). When a tonne of copper undergoes secondary processing, the value increases to US 27,390.20 (420% of the copper cathode value). The total revenue per week from the sales of the selected copper products was US 113,488.37.The total cost of production was estimated at US98,408.17 giving a gross Profit US15,080.20 (13.3% profit margin). In conclusion, this research has brought out important synoptic issues indicating the urgency of considering adding value to copper to earn more foreign exchange necessary for national development. It is therefore encouraged that investors and the government invest into…

Subjects/Keywords: Manufacturing cells – Zambia; Cells – Mechanical properties – Zambia; Copper work

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hamweendo, A. (2011). Design and evaluate a cellular manufacturing facility for selected copper products in Zambia . (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/547

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hamweendo, Agripa. “Design and evaluate a cellular manufacturing facility for selected copper products in Zambia .” 2011. Thesis, University of Zambia. Accessed April 14, 2021. http://hdl.handle.net/123456789/547.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hamweendo, Agripa. “Design and evaluate a cellular manufacturing facility for selected copper products in Zambia .” 2011. Web. 14 Apr 2021.

Vancouver:

Hamweendo A. Design and evaluate a cellular manufacturing facility for selected copper products in Zambia . [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/123456789/547.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hamweendo A. Design and evaluate a cellular manufacturing facility for selected copper products in Zambia . [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/547

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

9. Azote, Somiealo. Mechanical properties of cells and modelling of structural instabilities in tissues.

Degree: PhD, Physics, 2018, Stellenbosch University

URL: http://hdl.handle.net/10019.1/104963

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ENGLISH ABSTRACT : Cells have inherent mechanical properties that can be modelled physically. Statistical physics approaches permit the understanding of deformation dependence by modelling the… (more)

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ENGLISH ABSTRACT : Cells have inherent mechanical properties that can be modelled physically. Statistical physics approaches permit the understanding of deformation dependence by modelling the various elements of the cytoskeleton and combining these with the constraints and physical properties of the cell membrane. When cells combine to form more complex structures, including, for example, epithelial structures, the resulting structure also needs to be understood. We wish to understand the mechanical contribution to the elastic properties and stability of the cell within the tissue when branching actin cytoskeletal network emerge or grow and their structure, spatial organisation and orientational ordering geometrically constrained by the cell membrane. Based on a grand canonical ensemble formalism by Frisch et al. [1] and Müller-Nedebock et al. [2], we model the structure of branching actin networks of living cell cytoskeletal filaments when these are rigidly contained with geometrical confining regions. The formalism allows a thermodynamic equilibrium calculation of density and orientational order density for fillaments and branch points. We find distinct local orientation, order parameter and density profiles for network filament segments, as the degree of branching and the ratio of persistence lengths of the filaments to the confining region size are varied. These results suggest the role of the confinement in the structural properties and organization of branching actin networks inside the confining region. We next investigated the contribution of the elastic properties of the networks to the elastic properties and stability of the cells within tissues by computing the free energies and forces of networks system. We find that tissue cells are stable against compression while cell under shear become unstable beyond a critical angle.

AFRIKAANSE OPSOMMING : Selle het inherente eienskappe wat met die sika gemodelleer kan word. Statistiese ska benaderingspunte laat toe om die vervormingsafhankliheid te verstaan deur die modellering van verskillende elemente van die sitoskelet en om dit met die randkondisies en siese eienskape van die selmembraan te kombineer. Wanneer selle gekombineer word om meer komplekse strukture te vorm, insluitende, byvoorbeeld, epitele strukture, dan moet die resulterende struktuur ook ondersoek word. Ons wil die meganiese bydrae tot die elastiese eienskappe en die stabiliteit van die sel as deel van die weefsel verstaan, wanneer vertakkende aktien netwerke ontstaan en groei, en hulle struktuur, organisasie in die ruimte deur die geometrie van die sel ingeperk word. Gebaseer op n grootkanoniese formalisme van Frisch, et al., en van Müller-Nedebock et al. modelleer ons die struktuur van vertakkende aktien netwerke van dinamiese selle se sitoskelet- lamente wanneer hierdie tot starre geometriese gebiede beperk word. Die formalisme laat n berekening in die termodinamiese ewewig toe van die digtheid and orde in uitrigtings vir die lamente and vertakkingspunte. Ons…

Advisors/Committee Members: Müller-Nedebock, Kristian, Stellenbosch University. Faculty of Science. Dept. of Physics.

Subjects/Keywords: Cytoskeleton; Tissues; Cells – Mathematical models.; Cytoplasmic filaments; Cells – Mechanical properties; UCTD

10 more images…

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APA (6^th Edition):

Azote, S. (2018). Mechanical properties of cells and modelling of structural instabilities in tissues. (Doctoral Dissertation). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/104963

Chicago Manual of Style (16^th Edition):

Azote, Somiealo. “Mechanical properties of cells and modelling of structural instabilities in tissues.” 2018. Doctoral Dissertation, Stellenbosch University. Accessed April 14, 2021. http://hdl.handle.net/10019.1/104963.

MLA Handbook (7^th Edition):

Azote, Somiealo. “Mechanical properties of cells and modelling of structural instabilities in tissues.” 2018. Web. 14 Apr 2021.

Vancouver:

Azote S. Mechanical properties of cells and modelling of structural instabilities in tissues. [Internet] [Doctoral dissertation]. Stellenbosch University; 2018. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/10019.1/104963.

Council of Science Editors:

Azote S. Mechanical properties of cells and modelling of structural instabilities in tissues. [Doctoral Dissertation]. Stellenbosch University; 2018. Available from: http://hdl.handle.net/10019.1/104963

Columbia University

10. Patel, Tulsi. Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity.

Degree: 2016, Columbia University

URL: https://doi.org/10.7916/D8H1321F

► The plasticity of cells in a multicellular organism is progressively lost during differentiation. This loss is reflected in studies involving the ectopic misexpression of fate-specifying… (more)

▼ The plasticity of cells in a multicellular organism is progressively lost during differentiation. This loss is reflected in studies involving the ectopic misexpression of fate-specifying or terminal selector transcription factors (TFs). These TFs can efficiently activate target genes in undifferentiated cells, but lose this ability as cells differentiate. While this phenomenon of cell fate restriction is widely observed, the mechanisms orchestrating it are poorly understood. In this thesis, I have used the ubiquitous overexpression of Zn-finger-TF CHE-1 as a tool to understand the mechanisms that restrict cell fate in Caenorhabditis elegans. When CHE-1 is ubiquitously expressed at embryonic stages, it activates target gene expression in many cell types, while in adults it can only act in a few neurons. To uncover factors that inhibit plasticity of all other adult cells, I first performed an RNAi screen against chromatin-associated factors. Using this approach I found that the removal of either the PRC2 complex, which deposits the H3K27me3 mark, or loss of proteins that indirectly regulate domains of H3K27me3, allows CHE-1 and two other terminal selector TFs to activate target genes in the germline. These data show that the correct distribution of H3K27me3 is crucial for the restriction of germ cell fate. I next took a candidate approach to identify genes that regulate fate restriction in other cell types. We hypothesized that terminal selector TFs themselves, in addition to specifying cellular identity by controlling large gene sets, may also act to inhibit plasticity. To test this, I first assayed the activity of CHE-1 in mutants of COE-TF unc-3, the terminal selector for a subset of cholinergic motor neurons (MNs). I found that in contrast to wildtype MNs, unc-3 mutant MNs remain plastic as CHE-1 can induce expression of target genes in these cells even at the adult stage. This phenotype is also observed in four of six additional terminal selector mutants tested. I further found that the removal of met-2, a protein required for H3K9 methylation, or mes-2, a PRC2 component, also makes differentiated cholinergic MNs amenable to the activity of CHE-1. Preliminary evidence suggests that met-2 may act in the same pathway as unc-3. These results raise the exciting possibility that selector TFs play a role in restricting cell fate by organizing the heterochromatin domains in differentiated cells. Overall, in this work I provide functional evidence to show that specific chromatin-modifying enzymes restrict the fate of germ cells and that both fate-specifying TFs and chromatin-modifying enzymes are required for the fate restriction in neurons.

Subjects/Keywords: Cells; Caenorhabditis elegans; Cells – Mechanical properties; Chromatin; Plasticity; Genetics

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APA (6^th Edition):

Patel, T. (2016). Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8H1321F

Chicago Manual of Style (16^th Edition):

Patel, Tulsi. “Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity.” 2016. Doctoral Dissertation, Columbia University. Accessed April 14, 2021. https://doi.org/10.7916/D8H1321F.

MLA Handbook (7^th Edition):

Patel, Tulsi. “Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity.” 2016. Web. 14 Apr 2021.

Vancouver:

Patel T. Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity. [Internet] [Doctoral dissertation]. Columbia University; 2016. [cited 2021 Apr 14]. Available from: https://doi.org/10.7916/D8H1321F.

Council of Science Editors:

Patel T. Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity. [Doctoral Dissertation]. Columbia University; 2016. Available from: https://doi.org/10.7916/D8H1321F

East Carolina University

11. Moran, Marina. Correlating the Morphological and Light Scattering Properties of Biological Cells.

Degree: PhD, Physics, 2013, East Carolina University

URL: http://hdl.handle.net/10342/4235

► The scattered light pattern from a biological cell is greatly influenced by the internal structure and optical properties of the cell. This research project examines… (more)

▼ The scattered light pattern from a biological cell is greatly influenced by the internal structure and optical properties of the cell. This research project examines the relationships between the morphological and scattering properties of biological cells through numerical simulations. The mains goals are: (1) to develop a procedure to analytically model biological cells, (2) to quantitatively study the effects of a range of cell characteristics on the features of the light scattering patterns, and (3) to classify cells based on the features of their light scattering patterns. A procedure to create an analytical cell model was developed which extracted structural information from the confocal microscopic images of cells and allowed for the alteration of the cell structure in a controlled and systematic way. The influence of cell surface roughness, nuclear size, and mitochondrial volume density, spatial distribution, size and shape on the light scattering patterns was studied through numerical simulations of light scattering using the Discrete Dipole Approximation. It was found that the light scattering intensity in the scattering angle range of 25Â° to 45Â° responded to changes in the surface fluctuation of the cell and the range of 90Â° to 110Â° was well suited for characterization of mitochondrial density and nuclear size. A comparison of light scattering pattern analysis methods revealed that the angular distribution of the scattered light and Gabor filters were most helpful in differentiating between the cell characteristics. In addition, a measured increase in the Gabor energy of the light scattering patterns in response to an increase in the complexity of the cell models suggested that a complex nuclear structure and mitochondria should be included when modeling biological cells for light scattering simulations. Analysis of the scattering pattern features with Gabor filters resulted in discrimination of the cell models according to cell surface roughness, nuclear size, and mitochondrial volume density and size with over 90% classification accuracy. This study suggested the location of the scattering planes that are most relevant to researchers depending on the desired information about the cell and may provide a quantitative approach to cell discrimination with practical applications in flow cytometry for the diagnosis of diseases.Â Â Advisors/Committee Members: Lu, Jun Q. (advisor).

Subjects/Keywords: Physics; Cells – Mechanical properties; Cells – Morphology; Light – Scattering

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APA (6^th Edition):

Moran, M. (2013). Correlating the Morphological and Light Scattering Properties of Biological Cells. (Doctoral Dissertation). East Carolina University. Retrieved from http://hdl.handle.net/10342/4235

Chicago Manual of Style (16^th Edition):

Moran, Marina. “Correlating the Morphological and Light Scattering Properties of Biological Cells.” 2013. Doctoral Dissertation, East Carolina University. Accessed April 14, 2021. http://hdl.handle.net/10342/4235.

MLA Handbook (7^th Edition):

Moran, Marina. “Correlating the Morphological and Light Scattering Properties of Biological Cells.” 2013. Web. 14 Apr 2021.

Vancouver:

Moran M. Correlating the Morphological and Light Scattering Properties of Biological Cells. [Internet] [Doctoral dissertation]. East Carolina University; 2013. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/10342/4235.

Council of Science Editors:

Moran M. Correlating the Morphological and Light Scattering Properties of Biological Cells. [Doctoral Dissertation]. East Carolina University; 2013. Available from: http://hdl.handle.net/10342/4235

Rochester Institute of Technology

12. Dai, Yushuai. Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device.

Degree: MS, Center for Materials Science and Engineering, 2013, Rochester Institute of Technology

URL: https://scholarworks.rit.edu/theses/840

► Self-assembled quantum dots (QDs) and nanowires (NWs) are currently the subjects of extensive study due to their promising applications in optoelectronic devices. In order… (more)

▼ Self-assembled quantum dots (QDs) and nanowires (NWs) are currently the subjects of extensive study due to their promising applications in optoelectronic devices. In order to enhance understanding of the short circuit current improvement in InAs/GaAs quantum dots solar cell (QDSC), the mechanisms of carrier escape by thermal activation and tunneling from InAs quantum dots (QDs) confinements in InAs/GaAs QDSCs are investigated. The fitted activation energy of electrons from temperature dependent photoluminescence (TDPL) is 114 meV. Using this fitted activation energy, calculated thermal escape time and tunneling time of electrons from the ground state of the QDs are 10-12 seconds and 10-6 seconds at 300K, respectively. These results indicate that at room temperature thermal escape is dominant for electrons escape from ground state. At low temperature (8K), tunneling mainly affects the electrons escape from ground state, since thermal energy cannot support electrons to overcome the fitted activation energy (barrier, 114 meV). In addition, in order to describe the new physics and achieve the final success in nanowire device for photovoltaic applications, the first step is to develop high-quality semiconductor nanowires on the selected substrate. Morphological and crystal structure characterizations were performed via SEM and TEM for InAs nanowire samples grown with and without Au seed on GaAs substrate using metal organic vapor phase expitaxy (MOVPE). Several major factors affect the NW growth in terms of shape, density, etc. For nanowire growth with Au seed, its growth direction mainly depends on the substrate, while its uniformity is initially related to the Au seed coverage. III/V ratio affects the NW aspect ratio (length/bottom width), ranged from 12.00 to 38.93. Increasing temperature accelerates the growth rate in both axial and radial directions. NWs grown without Au seed using a pattern mask show no tapering along the growth direction with an average diameter of 26 nm. All defects stop in the buffer layer when InAs nanowires grown with an Au seed, but a mix of ZB and WZ crystal phases were observed along the growth direction of nanowire. InAs NWs grown without Au seeds also show a mixture of different crystal phases along the growth direction. The diameter of InAs nanowire should be further reduced to 3-6 nm as to achieve PL response between 1000~1300 nm. Advisors/Committee Members: Seth M. Hubbard.

Subjects/Keywords: Quantum dots – Optical properties; Quantum dots – Mechanical properties; Nanowires – Optical properties; Nanowires – Mechanical properties; Solar cells – Materials; Photovoltaic cells – Design and construction; Semiconductor and Optical Materials

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APA (6^th Edition):

Dai, Y. (2013). Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device. (Masters Thesis). Rochester Institute of Technology. Retrieved from https://scholarworks.rit.edu/theses/840

Chicago Manual of Style (16^th Edition):

Dai, Yushuai. “Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device.” 2013. Masters Thesis, Rochester Institute of Technology. Accessed April 14, 2021. https://scholarworks.rit.edu/theses/840.

MLA Handbook (7^th Edition):

Dai, Yushuai. “Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device.” 2013. Web. 14 Apr 2021.

Vancouver:

Dai Y. Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device. [Internet] [Masters thesis]. Rochester Institute of Technology; 2013. [cited 2021 Apr 14]. Available from: https://scholarworks.rit.edu/theses/840.

Council of Science Editors:

Dai Y. Optical and Mechanical Investigation of InAs /GaAs Quantum Dots Solar Cells and InAs Nanowires for the Application of Photovoltaic Device. [Masters Thesis]. Rochester Institute of Technology; 2013. Available from: https://scholarworks.rit.edu/theses/840

Michigan State University

13. Fan, Yin. Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria.

Degree: 2013, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:802

►

Thesis Ph. D. Michigan State University. Materials Science and Engineering 2013.

For a variety of applications of brittle ceramic materials, porosity plays a critical role… (more)

▼

Thesis Ph. D. Michigan State University. Materials Science and Engineering 2013.

For a variety of applications of brittle ceramic materials, porosity plays a critical role structurally and/or functionally, such as in engineered bone scaffolds, thermoelectric materials and in solid oxide fuel cells. The presence of porosity will affect the mechanical properties, which are essential to the design and application of porous brittle materials.In this study, the mechanical property versus microstructure relations for bioceramics, thermoelectric (TE) materials and solid oxide fuel cells were investigated. For the bioceramic material hydroxyapatite (HA), the Young's modulus was measured using resonant ultrasound spectroscopy (RUS) as a function of (i) porosity and (ii) microcracking damage state. The fracture strength was measured as a function of porosity using biaxial flexure testing, and the distribution of the fracture strength was studied by Weibull analysis. For the natural mineral tetrahedrite based solid solution thermoelectric material (Cu10Zn2As4S13 - Cu12Sb4S13), the elastic moduli, hardness and fracture toughness were studied as a function of (i) composition and (ii) ball milling time. For ZiNiSn, a thermoelectric half-Heusler compound, the elastic modulus - porosity and hardness - porosity relations were examined.For the solid oxide fuel cell material, gadolina doped ceria (GDC), the elastic moduli including Young's modulus, shear modulus, bulk modulus and Poisson's ratio were measured by RUS as a function of porosity. The hardness was evaluated by Vickers indentation technique as a function of porosity. The results of the mechanical property versus microstructure relations obtained in this study are of great importance for the design and fabrication of reliable components with service life and a safety factor. The Weibull modulus, which is a measure of the scatter in fracture strength, is the gauge of the mechanical reliability. The elastic moduli and Poisson's ratio are needed in analytical or numerical models of the thermal and mechanical stresses arising from in-service thermal gradients, thermal transients and/or mechanical loading. Hardness is related to a material's wear resistance and machinability, which are two essential considerations in fabrication and application.

Description based on online resource; title from PDF t.p. (viewed on Aug. 25, 2014)

Advisors/Committee Members: Case, Eldon D, Baumann, Melissa J, McCabe, Laura R, Hogan, Tim, Sakamoto, Jeffery.

Subjects/Keywords: Porosity; Hydroxyapatite – Mechanical properties; Hydroxyapatite – Microstructure; Thermoelectric materials – Mechanical properties; Thermoelectric materials – Microstructure; Solid oxide fuel cells – Mechanical properties; Solid oxide fuel cells – Microstructure; Materials Science

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APA (6^th Edition):

Fan, Y. (2013). Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:802

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fan, Yin. “Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria.” 2013. Thesis, Michigan State University. Accessed April 14, 2021. http://etd.lib.msu.edu/islandora/object/etd:802.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fan, Yin. “Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria.” 2013. Web. 14 Apr 2021.

Vancouver:

Fan Y. Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria. [Internet] [Thesis]. Michigan State University; 2013. [cited 2021 Apr 14]. Available from: http://etd.lib.msu.edu/islandora/object/etd:802.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fan Y. Mechanical characterization of hydroxyapatite, thermoelectric materials and doped ceria. [Thesis]. Michigan State University; 2013. Available from: http://etd.lib.msu.edu/islandora/object/etd:802

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

IUPUI

14. Hum, Julia M. Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress.

Degree: 2014, IUPUI

URL: http://hdl.handle.net/1805/4652

►

Indiana University-Purdue University Indianapolis (IUPUI)

Bone is a dynamic organ that responds to its external environment. Cell signaling cascades are initiated within bone cells when… (more)

▼

Indiana University-Purdue University Indianapolis (IUPUI)

Bone is a dynamic organ that responds to its external environment. Cell signaling cascades are initiated within bone cells when changes in mechanical loading occur. To describe these molecular signaling networks that sense a mechanical signal and convert it into a transcriptional response, we proposed the mechanosome model. “GO” and “STOP” mechansomes contain an adhesion-associated protein and a nucleocytoplasmic shuttling transcription factor. “GO” mechanosomes functions to promote the anabolic response of bone to mechanical loading, while “STOP” mechanosomes function to suppress the anabolic response of bone to mechanical loading. While much work has been done to describe the molecular mechanisms that enhance the anabolic response of bone to loading, less is known about the signaling mechanisms that suppress bone’s response to loading. We studied two adhesion-associated proteins, Src and Pyk2, which may function as “STOP” mechanosomes. Src kinase is involved in a number of signaling pathways that respond to changes in external loads on bone. An inhibition of Src causes an increase in the expression of the anabolic bone gene osteocalcin. Additionally, mechanical stimulation of osteoblasts and osteocytes by fluid shear stress further enhanced expression of osteocalcin when Src activity was inhibited. Importantly, fluid shear stress stimulated an increase in nuclear Src activation and activity. The mechanism by which Src participates in attenuating anabolic gene transcription remains unknown. The studies described here suggest Src and Pyk2 increase their association in response to fluid shear stress. Pyk2, a protein-tyrosine kinase, exhibits nucleocytoplasmic shuttling, increased association with methyl-CpG-binding protein 2 (MBD2), and suppression of osteopontin expression in response to fluid shear stress. MBD2, known to be involved in DNA methylation and interpretation of DNA methylation patterns, may aid in fluid shear stress-induced suppression of anabolic bone genes. We conclude that both Src and Pyk2 play a role in regulating bone mass, possibly through a complex with MBD2, and function to limit the anabolic response of bone cells to fluid shear stress through the suppression of anabolic bone gene expression. Taken together, these data support the hypothesis that “STOP” mechanosomes exist and their activity is simulated in response to fluid shear stress.

Advisors/Committee Members: Pavalko, Fredrick M., Bidwell, Joseph P., Day, Richard N., Elmendorf, Jeffrey S., Robling, Alexander G..

Subjects/Keywords: Mechanotransduction; Osteoblast; Osteocyte; Osteoblasts; Osteoblasts – Metabolism; Bones – Molecular aspects; Cells – Mechanical properties; Osteoclast inhibition; Musculoskeletal system – Mechanical properties; Human mechanics; Cell metabolism; Cellular signal transduction; DNA – Methylation; Protein-tyrosine kinase – Research; Gene expression; Cellular control mechanisms

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hum, J. M. (2014). Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress. (Thesis). IUPUI. Retrieved from http://hdl.handle.net/1805/4652

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hum, Julia M. “Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress.” 2014. Thesis, IUPUI. Accessed April 14, 2021. http://hdl.handle.net/1805/4652.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hum, Julia M. “Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress.” 2014. Web. 14 Apr 2021.

Vancouver:

Hum JM. Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress. [Internet] [Thesis]. IUPUI; 2014. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1805/4652.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hum JM. Signaling mechanisms that suppress the anabolic response of osteoblasts and osteocytes to fluid shear stress. [Thesis]. IUPUI; 2014. Available from: http://hdl.handle.net/1805/4652

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

IUPUI

15. Zhou, Hongkang. The essential role of Stat3 in bone homeostasis and mechanotransduction.

Degree: 2014, IUPUI

URL: http://hdl.handle.net/1805/6190

►

Indiana University-Purdue University Indianapolis (IUPUI)

Signal Transducer and Activator of Transcription 3 (Stat3) is a transcription factor expressed in bone and joint cells that include… (more)

▼

Indiana University-Purdue University Indianapolis (IUPUI)

Signal Transducer and Activator of Transcription 3 (Stat3) is a transcription factor expressed in bone and joint cells that include osteoblasts, osteocytes, osteoclasts, and chondrocytes. Stat3 is activated by a variety of cytokines and growth factors, including IL-6/gp130 family cytokines. These cytokines not only regulate the differentiation of osteoblasts and osteoclasts, but also regulate proliferation of chondrocytes through Stat3 activation. In 2007, mutations of Stat3 have been confirmed to cause a rare human immunodeficiency disease – Job syndrome which presents skeletal abnormalities like: reduced bone density (osteopenia), scoliosis, hyperextensibility of joints, and recurrent pathological bone fractures. Changes in the Stat3 gene alter the structure and function of the Stat3 proteins, impairing its ability to control the activity of other genes. However, little is known about the effects of Stat3 mutations on bone cells and tissues. To investigate the in vivo physiological role of Stat3 in bone homeostasis, osteoblast/osteocyte-specific Stat3 knockout (KO) mice were generated via the Cre-LoxP recombination system. The osteoblast/osteocyte-specific Stat3 KO mice showed bone abnormalities and an osteoporotic phenotype because of a reduced bone formation rate. Furthermore, inactivation of Stat3 decreased load-driven bone formation, and the disruption of Stat3 in osteoblasts suppressed load-driven mitochondrial activity, which led to an elevated level of reactive oxygen species (ROS) in cultured primary osteoblasts. Stat3 has been found to be responsive to mechanical stimulation, and might play an important role in mechanical signal transduction in osteocytes. To investigate the role Stat3 plays in mechanical signaling transduction, osteocyte-specific Stat3 knockout (KO) mice were created. Inactivation of Stat3 in osteocytes presented a significantly reduced load-driven bone formation. Decreased osteoblast activity indicated by reduced osteoid surface was also found in osteocyte-specific Stat3 KO mice. Moreover, sclerostin (SOST) protein which is a critical osteocyte-specific inhibitor of bone formation, its encoded gene SOST expression has been found to be enhanced in osteocyte-specific Stat3 KO mice. Thus, these results clearly demonstrated that Stat3 plays an important role in bone homeostasis and mechanotransduction, and Stat3 is not only involved in bone-formation-important genes regulation in the nucleus but also in mediation of ROS and oxidative stress in mitochondria.

Advisors/Committee Members: Li, Jiliang, Marrs, James, Stocum, David L., Atkinson, Simon, Aguilar, R. Claudio, Yokota, Hiroki, 1955-.

Subjects/Keywords: Signal Transducer and Activator of Transcription 3; Bone formation; Osteoblast; Osteocyte; Mechanotransduction; Bones – Growth – Research – Analysis – Evaluation; Bones – Growth – Molecular aspects; Musculoskeletal system – Mechanical properties; Human mechanics; Bones – Physiology; Biomechanics – Research; Bones – Metabolism – Research – Analysis – Evaluation; Bones – Metabolism – Disorders; Osteocytes – Research; Osteoblasts – Research; Osteoclasts – Research; Bone cells – Research; Cellular signal transduction – Research; Transcription factors – Research; Bone remodeling

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zhou, H. (2014). The essential role of Stat3 in bone homeostasis and mechanotransduction. (Thesis). IUPUI. Retrieved from http://hdl.handle.net/1805/6190

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zhou, Hongkang. “The essential role of Stat3 in bone homeostasis and mechanotransduction.” 2014. Thesis, IUPUI. Accessed April 14, 2021. http://hdl.handle.net/1805/6190.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zhou, Hongkang. “The essential role of Stat3 in bone homeostasis and mechanotransduction.” 2014. Web. 14 Apr 2021.

Vancouver:

Zhou H. The essential role of Stat3 in bone homeostasis and mechanotransduction. [Internet] [Thesis]. IUPUI; 2014. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1805/6190.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhou H. The essential role of Stat3 in bone homeostasis and mechanotransduction. [Thesis]. IUPUI; 2014. Available from: http://hdl.handle.net/1805/6190

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ryerson University

16. Zafar, Maliha. Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells.

Degree: 2015, Ryerson University

URL: https://digital.library.ryerson.ca/islandora/object/RULA%3A4189

► Nucleosides and nucleoside analog drugs enter cells through nucleoside transporters, such as the human equilibrative nucleoside transporter 1 (hENT1). The regulation of nucleoside transporters is… (more)

Subjects/Keywords: Cells – Mechanical properties; Nucleosides; Biological transport; Carrier proteins; Drug carriers (Pharmacy)

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APA (6^th Edition):

Zafar, M. (2015). Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells. (Thesis). Ryerson University. Retrieved from https://digital.library.ryerson.ca/islandora/object/RULA%3A4189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zafar, Maliha. “Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells.” 2015. Thesis, Ryerson University. Accessed April 14, 2021. https://digital.library.ryerson.ca/islandora/object/RULA%3A4189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zafar, Maliha. “Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells.” 2015. Web. 14 Apr 2021.

Vancouver:

Zafar M. Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells. [Internet] [Thesis]. Ryerson University; 2015. [cited 2021 Apr 14]. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A4189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zafar M. Substrate Dependent Regulation of the Human Equilibrative Nucleoside Transporter 1 (hENT1) in HEK293 Cells. [Thesis]. Ryerson University; 2015. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A4189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Toronto

17. Raz, Neta. Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation.

Degree: 2010, University of Toronto

URL: http://hdl.handle.net/1807/25903

►

In this study the role of passive mechanism for deformation of neutrophils, namely the effect of mechanical properties, was studied using microgels as model system.… (more)

Subjects/Keywords: microgels; artificial cells; pulmonary microcirculation; mechanical properties; 0495

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APA (6^th Edition):

Raz, N. (2010). Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation. (Masters Thesis). University of Toronto. Retrieved from http://hdl.handle.net/1807/25903

Chicago Manual of Style (16^th Edition):

Raz, Neta. “Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation.” 2010. Masters Thesis, University of Toronto. Accessed April 14, 2021. http://hdl.handle.net/1807/25903.

MLA Handbook (7^th Edition):

Raz, Neta. “Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation.” 2010. Web. 14 Apr 2021.

Vancouver:

Raz N. Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation. [Internet] [Masters thesis]. University of Toronto; 2010. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/1807/25903.

Council of Science Editors:

Raz N. Microgels as Artificial Cells in Modeling the Flow of Neutrophils in the Pulmonary Microcirculation. [Masters Thesis]. University of Toronto; 2010. Available from: http://hdl.handle.net/1807/25903

Columbia University

18. Lee, Kristen Lauren. A Mechanism of Mechanotransduction Mediated by the Primary Cilium.

Degree: 2014, Columbia University

URL: https://doi.org/10.7916/D8KP80BQ

► Mechanotransduction is a process by which cells sense and convert mechanical loads into biochemical signals and transcriptional changes. This process is particularly critical in bone,… (more)

Subjects/Keywords: Cells – Mechanical properties; Bones – Growth; Biomedical engineering; Molecular biology

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APA (6^th Edition):

Lee, K. L. (2014). A Mechanism of Mechanotransduction Mediated by the Primary Cilium. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8KP80BQ

Chicago Manual of Style (16^th Edition):

Lee, Kristen Lauren. “A Mechanism of Mechanotransduction Mediated by the Primary Cilium.” 2014. Doctoral Dissertation, Columbia University. Accessed April 14, 2021. https://doi.org/10.7916/D8KP80BQ.

MLA Handbook (7^th Edition):

Lee, Kristen Lauren. “A Mechanism of Mechanotransduction Mediated by the Primary Cilium.” 2014. Web. 14 Apr 2021.

Vancouver:

Lee KL. A Mechanism of Mechanotransduction Mediated by the Primary Cilium. [Internet] [Doctoral dissertation]. Columbia University; 2014. [cited 2021 Apr 14]. Available from: https://doi.org/10.7916/D8KP80BQ.

Council of Science Editors:

Lee KL. A Mechanism of Mechanotransduction Mediated by the Primary Cilium. [Doctoral Dissertation]. Columbia University; 2014. Available from: https://doi.org/10.7916/D8KP80BQ

Columbia University

19. Wang, Shuyuan. Mathematically Modeling the Mechanics of Cell Division.

Degree: 2018, Columbia University

URL: https://doi.org/10.7916/D8G74S6H

► The final stage of the cell cycle is cell division by cytokinesis, when the cell physically separates into two daughter cells. Improper timing or location… (more)

▼ The final stage of the cell cycle is cell division by cytokinesis, when the cell physically separates into two daughter cells. Improper timing or location of the division site results in incorrect segregation of chromosomes and thus genetically unstable aneuploid cells, which is associated with tumorigenesis. Cytokinesis in animal, fungal and amoeboid cells occurs through the assembly and constriction of an actomyosin contractile ring, a mechanism that dates back about one billion years in the common ancestor of these organisms. However, it is not well understood how the ring generates tension or how the rate of ring constriction is set. Long ago a sliding filament mechanism similar to skeletal muscle was proposed, but definitive evidence for muscle-like sarcomeric order in the ring is lacking. Here we build mathematical models of cytokinesis in the fission yeast Schizosaccharomyces pombe, where the most complete inventory of more than 150 cytokinesis genes have been documented. The models explicitly represent proteins in the contractile ring such as formin, myosin, actin, α-actinin, etc. and implements their quantities, biomechanical properties and organizations from the best available experimental information. At the same time, the models adopt coarse-grain approaches that are able to describe the collective behaviors of thousands of ring components, which include tension production, constriction, and disassembly of the ring. In the first part of this thesis, we modeled the extraordinarily rapid constriction of the partially unanchored ring in fission yeast cell ghosts. Experiments on isolated fission yeast rings showed sections of ring unanchoring from the membrane and shortening ~30-fold faster than normal (1). We demonstrated that anchoring of actin to the plasma membrane generates tension in the fission yeast cytokinetic ring by showing (1) unanchored segments in these experiments were tensionless, and (2) only a barbed-end anchoring of actin can generate tension in the normally anchored ring, and can explain the extraordinary behavior of unanchored segments. Molecularly explicit simulations accurately reproduced experimental constriction rates, and showed a novel non-contractile reeling-in mechanism by which the unanchored segment shortens, despite being tensionless. In the second part of this thesis, we built a highly coarse-grained model to study how ring tension is generated and how structural stability is maintained. Recently, a super-resolution microscopy study of the fission yeast ring revealed that myosins and formins that nucleate actin filaments colocalize in plasma membrane-anchored complexes called nodes in the constricting ring (2). The nodes move bidirectionally around the ring. Here we construct and analyze a coarse-grained mathematical model of the fission yeast ring to explore essential consequences of the recently discovered ring ultrastructure. The model reproduces experimentally measured values of ring tension, explains why nodes move bidirectionally and shows that tension…

Subjects/Keywords: Physics; Biophysics; Cell division; Cytokinesis – Mathematical models; Cells – Mechanical properties

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APA (6^th Edition):

Wang, S. (2018). Mathematically Modeling the Mechanics of Cell Division. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8G74S6H

Chicago Manual of Style (16^th Edition):

Wang, Shuyuan. “Mathematically Modeling the Mechanics of Cell Division.” 2018. Doctoral Dissertation, Columbia University. Accessed April 14, 2021. https://doi.org/10.7916/D8G74S6H.

MLA Handbook (7^th Edition):

Wang, Shuyuan. “Mathematically Modeling the Mechanics of Cell Division.” 2018. Web. 14 Apr 2021.

Vancouver:

Wang S. Mathematically Modeling the Mechanics of Cell Division. [Internet] [Doctoral dissertation]. Columbia University; 2018. [cited 2021 Apr 14]. Available from: https://doi.org/10.7916/D8G74S6H.

Council of Science Editors:

Wang S. Mathematically Modeling the Mechanics of Cell Division. [Doctoral Dissertation]. Columbia University; 2018. Available from: https://doi.org/10.7916/D8G74S6H

Hong Kong University of Science and Technology

20. Zhao, Yihua. Fabrication of microfluidic devices and their applications in chemical and biological analysis.

Degree: 2013, Hong Kong University of Science and Technology

URL: http://repository.ust.hk/ir/Record/1783.1-62268 ; https://doi.org/10.14711/thesis-b1251138 ; http://repository.ust.hk/ir/bitstream/1783.1-62268/1/th_redirect.html

► Microfluidic technologies are emerging as powerful tools for biological study including tissue, single cell or even single molecule level analysis in parallel. A small volume… (more)

Subjects/Keywords: Microfluidic devices ; Design and construction ; Cells ; Mechanical properties ; Analysis ; Polytef

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APA (6^th Edition):

Zhao, Y. (2013). Fabrication of microfluidic devices and their applications in chemical and biological analysis. (Thesis). Hong Kong University of Science and Technology. Retrieved from http://repository.ust.hk/ir/Record/1783.1-62268 ; https://doi.org/10.14711/thesis-b1251138 ; http://repository.ust.hk/ir/bitstream/1783.1-62268/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zhao, Yihua. “Fabrication of microfluidic devices and their applications in chemical and biological analysis.” 2013. Thesis, Hong Kong University of Science and Technology. Accessed April 14, 2021. http://repository.ust.hk/ir/Record/1783.1-62268 ; https://doi.org/10.14711/thesis-b1251138 ; http://repository.ust.hk/ir/bitstream/1783.1-62268/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zhao, Yihua. “Fabrication of microfluidic devices and their applications in chemical and biological analysis.” 2013. Web. 14 Apr 2021.

Vancouver:

Zhao Y. Fabrication of microfluidic devices and their applications in chemical and biological analysis. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2013. [cited 2021 Apr 14]. Available from: http://repository.ust.hk/ir/Record/1783.1-62268 ; https://doi.org/10.14711/thesis-b1251138 ; http://repository.ust.hk/ir/bitstream/1783.1-62268/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhao Y. Fabrication of microfluidic devices and their applications in chemical and biological analysis. [Thesis]. Hong Kong University of Science and Technology; 2013. Available from: http://repository.ust.hk/ir/Record/1783.1-62268 ; https://doi.org/10.14711/thesis-b1251138 ; http://repository.ust.hk/ir/bitstream/1783.1-62268/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Colorado School of Mines

21. Roth, Kevin B. Combination of hydrodynamic and optical forces for cell mechanical flow cytometry.

Degree: PhD, Chemical and Biological Engineering, 2015, Colorado School of Mines

URL: http://hdl.handle.net/11124/17108

► Cell mechanical properties are a label-free biomarker capable of differentiating between healthy and diseased cells. Currently, cell deformability is measured by testing the mechanics of… (more)

▼ Cell mechanical properties are a label-free biomarker capable of differentiating between healthy and diseased cells. Currently, cell deformability is measured by testing the mechanics of a suspension of cells to yield population averaged properties. This approach can mask the presence of sub-populations of diseased cells. Alternatively, individual cell measurements provide detailed information of individual cells, but are inherently low throughput, making data acquisition tedious and scale-up impractical. To address these issues, we propose using optical-based cell deformation techniques in microfluidic platforms to measure cell mechanical properties non-invasively, non-destructively and in a high-throughput manner (> 1 cell/s). In this thesis two different techniques are proposed: optical alignment compression (OAC) cytometry and optical stretching in flow. Both techniques combine optical and hydrodynamic forces in low Reynolds number flows. In OAC cytometry, an aligning optical trap is combined with extensional flow in a microfluidic device to allow hydrodynamic forces to cause measurable deformation through cell-cell collisions at the flow stagnation point. Results demonstrate the utility of optical-based testing by testing two red blood cell systems. To further examine optically based techniques, we employ optical forces to induce deformation. In optical stretching with improved laser imaging, a linear diode bar laser is aligned parallel to flow in a microfluidic device to deform cells that pass through the trap. The combination of optical and hydrodynamic forces at high flow rates allows for high-throughput measurements (~50 cells/s). Technique viability is tested with both red blood cells and neutrophils. By considering these two approaches we will characterize the interplay of optical and hydrodynamic forces and their contributions to cell deformation in optical-based cell mechanical property testing. Advisors/Committee Members: Marr, David W. M. (advisor), Neeves, Keith B. (advisor), Squier, Jeff A. (committee member), Silverman, Anne K. (committee member), Wu, Ning (committee member).

Subjects/Keywords: Flow cytometry; Cells – Mechanical properties; Optics; Hydrodynamics; Microfluidics

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APA (6^th Edition):

Roth, K. B. (2015). Combination of hydrodynamic and optical forces for cell mechanical flow cytometry. (Doctoral Dissertation). Colorado School of Mines. Retrieved from http://hdl.handle.net/11124/17108

Chicago Manual of Style (16^th Edition):

Roth, Kevin B. “Combination of hydrodynamic and optical forces for cell mechanical flow cytometry.” 2015. Doctoral Dissertation, Colorado School of Mines. Accessed April 14, 2021. http://hdl.handle.net/11124/17108.

MLA Handbook (7^th Edition):

Roth, Kevin B. “Combination of hydrodynamic and optical forces for cell mechanical flow cytometry.” 2015. Web. 14 Apr 2021.

Vancouver:

Roth KB. Combination of hydrodynamic and optical forces for cell mechanical flow cytometry. [Internet] [Doctoral dissertation]. Colorado School of Mines; 2015. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/11124/17108.

Council of Science Editors:

Roth KB. Combination of hydrodynamic and optical forces for cell mechanical flow cytometry. [Doctoral Dissertation]. Colorado School of Mines; 2015. Available from: http://hdl.handle.net/11124/17108

Colorado School of Mines

22. Kasukurti, Aditya. Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery.

Degree: PhD, Chemical and Biological Engineering, 2014, Colorado School of Mines

URL: http://hdl.handle.net/11124/16984

► With the existence and emerging importance of cellular heterogeneity there has been a push in the microbiology community for new tools to study at the… (more)

▼ With the existence and emerging importance of cellular heterogeneity there has been a push in the microbiology community for new tools to study at the individual cells. To meet the need to identify, characterize and isolate single cells of interest from bulk samples, precise and directed forces on the order of picoNewtons are necessary. To generate these forces, we combine optical and hydrodynamic methods enabled by microfluidic platforms that operate in regimes where viscous forces dominate and hydrodynamics is readily predicted and controlled. We have developed techniques for the characterization, isolation and delivery of individual cells using combinations of optical and hydrodynamic forces. First, we use optical forces to demonstrate real-time measurement of single-cell dynamic viscoelasticity while using hydrodynamic forces to move cells in and out of the optical trap to enable high-throughput (3000 cells/hr). Second, we use optical forces for the isolation of cells and hydrodynamic properties of laminar flow to amplify this isolation. Finally, we use this single-cell isolation scheme in a microfluidic platform with a novel chip-to-world sample delivery scheme that can be integrated with a variety of available cell isolation technologies. In this, an optical trap was employed to generate the necessary forces to precisely capture and isolate single cells from the bulk population, while hydrodynamic forces were used to amplify this isolation and deliver single cells as falling droplets that can be collected onto 96-well plates. These hydrodynamic forces were generated and precisely directed with microfluidic features including hydraulic resistances, hydrofocusing vaults, compliance reservoirs, and selective surface coatings to scale from the micrometer scale of single cells to the millimeter scale of well plates. Advisors/Committee Members: Marr, David W. M. (advisor), Posewitz, Matthew C. (committee member), Wu, Ning (committee member), Neeves, Keith B. (committee member), Squier, Jeff A. (committee member).

Subjects/Keywords: single cell; cell mechanical properties; optical trapping; microfluidics; cytometer; Cell separation; Cells – Mechanical properties; Microfluidics; Hydrodynamics; Separation (Technology); Viscoelasticity

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APA (6^th Edition):

Kasukurti, A. (2014). Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery. (Doctoral Dissertation). Colorado School of Mines. Retrieved from http://hdl.handle.net/11124/16984

Chicago Manual of Style (16^th Edition):

Kasukurti, Aditya. “Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery.” 2014. Doctoral Dissertation, Colorado School of Mines. Accessed April 14, 2021. http://hdl.handle.net/11124/16984.

MLA Handbook (7^th Edition):

Kasukurti, Aditya. “Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery.” 2014. Web. 14 Apr 2021.

Vancouver:

Kasukurti A. Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery. [Internet] [Doctoral dissertation]. Colorado School of Mines; 2014. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/11124/16984.

Council of Science Editors:

Kasukurti A. Combining optical and hydrodynamic forces for single cell characterization, isolation and delivery. [Doctoral Dissertation]. Colorado School of Mines; 2014. Available from: http://hdl.handle.net/11124/16984

RMIT University

23. Mustapa, I. Biocomposites including nano-scale dispersed phase and polymers from renewable resources.

Degree: 2014, RMIT University

URL: http://researchbank.rmit.edu.au/view/rmit:160820

► Poly(lactic acid) (PLA) was physically modified by filling with an inorganic additive, natural fibres as well as with a tributyl citrate (TBC). PLA composites were… (more)

▼ Poly(lactic acid) (PLA) was physically modified by filling with an inorganic additive, natural fibres as well as with a tributyl citrate (TBC). PLA composites were prepared with a film stacking method and analysed by scanning electron microscopy (SEM), thermogravimetry (TGA), thermomechanometry and differential scanning calorimetry (DSC) to investigate the physical and mechanical properties of the hybrid composites. PLA composites reinforced with hemp fibres in combination with nanosilica are thermally stable as the maximum rate of weight loss of the composites shifted to the highest temperature observed in TGA results. Dynamic mechanical properties of PLA composites showed that the reinforcement of hemp fibre and nanosilica strongly affected the mechanical properties of the composites. The highest storage modulus improvements were reached by addition of hemp fibre and nanosilica without plasticiser. An increase in storage modulus monitored in the temperature region from 70 to 100 Â°C reflected an increase in structural stiffness due to recrystallisation activity in the composites. The addition of TBC reduced the modulus though initiated the crystallisation on cooling, enhanced the nucleating ability of the fillers and chain mobility in PLA composites. The melting and crystallisation behaviour of PLA composites was explored with non isothermal DSC at various scanning rates. The characteristics of the crystallisation and melting behaviour of PLA composites were explained by the slow rate of crystallisation and recrystallisation, which is in agreement with DMA results. Non-isothermal crystallization kinetics shows that the crystallization rate of PLA composites was higher than of neat PLA and further increased with presence of TBC, indicating that the addition of plasticiser and nucleating agents enhanced the transportation ability of polymer chains. SEM revealed a good distribution of nanosilica for composites with and without TBC. A great transfer of stress between hemp fibres and PLA nanosilica matrix resulted in improved of physical and mechanical properties as evidenced by DMA and DSC results.

Subjects/Keywords: Fields of Research; Biodegradable Polymer; Mechanical properties; Thermal properties; Crystallization; Morphology; Nucleation

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APA (6^th Edition):

Mustapa, I. (2014). Biocomposites including nano-scale dispersed phase and polymers from renewable resources. (Thesis). RMIT University. Retrieved from http://researchbank.rmit.edu.au/view/rmit:160820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mustapa, I. “Biocomposites including nano-scale dispersed phase and polymers from renewable resources.” 2014. Thesis, RMIT University. Accessed April 14, 2021. http://researchbank.rmit.edu.au/view/rmit:160820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mustapa, I. “Biocomposites including nano-scale dispersed phase and polymers from renewable resources.” 2014. Web. 14 Apr 2021.

Vancouver:

Mustapa I. Biocomposites including nano-scale dispersed phase and polymers from renewable resources. [Internet] [Thesis]. RMIT University; 2014. [cited 2021 Apr 14]. Available from: http://researchbank.rmit.edu.au/view/rmit:160820.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mustapa I. Biocomposites including nano-scale dispersed phase and polymers from renewable resources. [Thesis]. RMIT University; 2014. Available from: http://researchbank.rmit.edu.au/view/rmit:160820

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Northeastern University

24. Oftadeh, Ramin. Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure.

Degree: PhD, Department of Mechanical and Industrial Engineering, 2016, Northeastern University

URL: http://hdl.handle.net/2047/D20212379

► Materials with structural hierarchy over nanometer to millimeter length scales are found throughout Kingdoms Plantae and Animalia. The idea of using structural hierarchy in engineering… (more)

▼ Materials with structural hierarchy over nanometer to millimeter length scales are found throughout Kingdoms Plantae and Animalia. The idea of using structural hierarchy in engineering structures and materials goes back at least to Eiffel's Garabit Viaduct and then Tower. Incorporating hierarchy into honeycomb lattice structures has been the focus of a number of studies and has significance with regard to the application of honeycombs in impact energy absorption and structural protection, thermal isolation and as the structural core of sandwich panels. Here we explore the mechanical properties of two kind of cellular structures: hierarchical honeycombs and trabecular bone.; Hexagonal honeycomb structures are known for their high strength and low weight. We construct a new class of fractal-appearing cellular metamaterials by replacing each three-edge vertex of a base hexagonal network with a smaller hexagon and iterating this process. The mechanical properties of the structure after different orders of the iteration are optimized. We find that the optimal structure (with highest in-plane stiffness for a given weight ratio) is self-similar but requires higher order hierarchy as the density vanishes. These results offer insights into how incorporating hierarchy in the material structure can create low-density metamaterials with desired properties and function.; The second aim of this study was to explore the hierarchical arrangement of structural properties in cortical and trabecular bone and to determine a mathematical model that accurately predicts the tissue's mechanical properties as a function of these indices. By using a variety of analytical techniques, we were able to characterize the structural and compositional properties of cortical and trabecular bones, as well as to determine the suitable mathematical model to predict the tissue's mechanical properties using a continuum micromechanics approach. Our hierarchical analysis demonstrated that the differences between cortical and trabecular bone reside mainly at the micro- and ultrastructural levels. By gaining a better appreciation of the similarities and differences between the two bone types, we would be able to provide a better assessment and understanding of their individual roles, as well as their contribution to bone health overall.

Subjects/Keywords: bone composition; bone structure; cellular structures; cortical bone; structural hierarchy; trabecular bone; Structural design; Bone; Mechanical properties; Connective tissues; Mechanical properties; Honeycomb structures; Mechanical properties; Composite materials; Cells

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APA (6^th Edition):

Oftadeh, R. (2016). Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure. (Doctoral Dissertation). Northeastern University. Retrieved from http://hdl.handle.net/2047/D20212379

Chicago Manual of Style (16^th Edition):

Oftadeh, Ramin. “Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure.” 2016. Doctoral Dissertation, Northeastern University. Accessed April 14, 2021. http://hdl.handle.net/2047/D20212379.

MLA Handbook (7^th Edition):

Oftadeh, Ramin. “Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure.” 2016. Web. 14 Apr 2021.

Vancouver:

Oftadeh R. Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure. [Internet] [Doctoral dissertation]. Northeastern University; 2016. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/2047/D20212379.

Council of Science Editors:

Oftadeh R. Hierarchical analysis and multiscale modelling of cellular structures: from meta materials to bone structure. [Doctoral Dissertation]. Northeastern University; 2016. Available from: http://hdl.handle.net/2047/D20212379

RMIT University

25. Anjang Ab Rahman, A. Fire structural properties of sandwich composites.

Degree: 2015, RMIT University

URL: http://researchbank.rmit.edu.au/view/rmit:161379

► The main aim of this PhD project is to investigate the fire structural properties of a sandwich composite representative of the material used in naval… (more)

▼ The main aim of this PhD project is to investigate the fire structural properties of a sandwich composite representative of the material used in naval ship structures. Using experimental techniques and analytical models, this PhD investigates the structural response of sandwich composites during and following fire exposure. The thermal, physical and mechanical processes controlling the softening and failure of the sandwich composite under structural loading and one-sided heating by fire are determined. Two important structural loading cases of axial tension and axial compression are studied together with different radiant heat flux conditions representative of fires with different flame temperatures. To thoroughly understand the fire response of sandwich composites, this PhD determines the temperature response, softening behaviour, deformation, damage and failure mechanisms for different loading conditions, stress levels and heat flux conditions. In post-fire structural properties, reductions to the tensile and compressive properties of sandwich composites following fire exposure are investigated experimentally and analytically. The processes and mechanisms controlling the post-fire stiffness and strength properties of sandwich composites are determined. This PhD project also assesses the effect of water absorption on the fire structural response of sandwich composites. The sandwich composite was exposed to a hot-wet environment for increasing periods of time to controllably alter the amount of absorbed water. The effect of absorbed water on the thermal and mechanical responses of the sandwich composite in fire is experimentally determined. The research determines changes to the thermal response, damage, softening rate and failure mode of the sandwich material with increasing concentration of absorbed water up to and above saturation. This PhD research work establishes a better understanding of mechanical performance and failure mechanisms of sandwich composite structures at high temperature and in fire. In addition, the research identifies the thermal, physical and mechanical processes that control the structural survivability of sandwich composites during and following fire exposure. The research provides the foundation for the development of design models and guidelines for sandwich composite structures for high fire risk applications, thus improving fire safety for ships, offshore platforms, civil infrastructures and other uses for these materials.

Subjects/Keywords: Fields of Research; Fire Performance; Sandwich Composites; Mechanical Properties

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APA (6^th Edition):

Anjang Ab Rahman, A. (2015). Fire structural properties of sandwich composites. (Thesis). RMIT University. Retrieved from http://researchbank.rmit.edu.au/view/rmit:161379

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Anjang Ab Rahman, A. “Fire structural properties of sandwich composites.” 2015. Thesis, RMIT University. Accessed April 14, 2021. http://researchbank.rmit.edu.au/view/rmit:161379.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Anjang Ab Rahman, A. “Fire structural properties of sandwich composites.” 2015. Web. 14 Apr 2021.

Vancouver:

Anjang Ab Rahman A. Fire structural properties of sandwich composites. [Internet] [Thesis]. RMIT University; 2015. [cited 2021 Apr 14]. Available from: http://researchbank.rmit.edu.au/view/rmit:161379.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Anjang Ab Rahman A. Fire structural properties of sandwich composites. [Thesis]. RMIT University; 2015. Available from: http://researchbank.rmit.edu.au/view/rmit:161379

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

RMIT University

26. Li, L. Service life prediction of bridges subjected to corrosion using time-dependent reliability method.

Degree: 2018, RMIT University

URL: http://researchbank.rmit.edu.au/view/rmit:162530

► Bridges are key infrastructures that play an important role in transport systems, but the deterioration of this infrastructure has become a worldwide issue. This deterioration… (more)

▼ Bridges are key infrastructures that play an important role in transport systems, but the deterioration of this infrastructure has become a worldwide issue. This deterioration affects the capacity of a bridge structure and reduces its remaining life. It is, therefore, vital to study the corrosion effect on bridges and carry out service life prediction of bridges subjected to corrosion to avoid corrosion-induced failures and develop cost-efficient methods for the maintenance and rehabilitation of bridges. The research aimed to develop a new method to predict the service life of a bridge subjected to corrosion. The first-passage probability theory was used to determine the time-dependent probability of bridge failure under different failure criterion and, subsequently, the service life of the bridge. To obtain accurate input information, simulated corrosion tests were conducted to determine the corrosion behaviour of steel with and without stress. Mechanical tests were undertaken to determine the degradation effect of corrosion on mechanical properties (yield strength, ultimate strength, failure strain and fatigue strength limitation) with and without stress. Hydrogen concentration measurement and microstructural analysis were conducted to determine the mechanism of corrosion-induced degradation of mechanical properties of steel with and without stress. Results of lab tests were correlated to natural corrosion through site inspection. Based on the results collected from corrosion tests and site inspection, bridge geometry and mechanical properties of bridge steel were modelled as time-dependent variables when carrying out time-dependent reliability analysis. It was concluded that corrosion can lead to the reduction of ultimate strength and failure strain of steel. Corrosion can also cause delamination due to intrinsic differences in the microstructure across the thickness of steel plates. Additionally, the levels of reduction of mechanical properties and propagation of delamination are higher for stressed steel than for non-stressed steel at the same degree of corrosion. Also, due to the effect of corrosion, the stress range (S) magnitude for corroded steel is smaller than that for un-corroded steel at the same number of load cycles (N) to failure in the S-N curve. The research also indicated the degradation of mechanical properties is caused by corrosion- and hydrogen-induced changes in microstructural features. It was found, through reliability analysis, that fatigue failure is the most critical failure criterion and that not considering the effect of corrosion on mechanical properties leads to overestimation of the service life of bridges.

Subjects/Keywords: Fields of Research; corrosion; steel bridge; fatigue; mechanical properties; service life

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APA (6^th Edition):

Li, L. (2018). Service life prediction of bridges subjected to corrosion using time-dependent reliability method. (Thesis). RMIT University. Retrieved from http://researchbank.rmit.edu.au/view/rmit:162530

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, L. “Service life prediction of bridges subjected to corrosion using time-dependent reliability method.” 2018. Thesis, RMIT University. Accessed April 14, 2021. http://researchbank.rmit.edu.au/view/rmit:162530.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, L. “Service life prediction of bridges subjected to corrosion using time-dependent reliability method.” 2018. Web. 14 Apr 2021.

Vancouver:

Li L. Service life prediction of bridges subjected to corrosion using time-dependent reliability method. [Internet] [Thesis]. RMIT University; 2018. [cited 2021 Apr 14]. Available from: http://researchbank.rmit.edu.au/view/rmit:162530.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li L. Service life prediction of bridges subjected to corrosion using time-dependent reliability method. [Thesis]. RMIT University; 2018. Available from: http://researchbank.rmit.edu.au/view/rmit:162530

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide

27. Rumman, Md. Raihanuzzaman. Effect of particle size and sintering processes on mechanical properties of cemented carbides.

Degree: 2016, University of Adelaide

URL: http://hdl.handle.net/2440/115418

► Cemented carbide has been widely used as hard materials in industrial machining as cutting tools and as moulds in metal shaping. Prior research suggests that… (more)

▼ Cemented carbide has been widely used as hard materials in industrial machining as cutting tools and as moulds in metal shaping. Prior research suggests that many processing techniques have been applied to improve its manufacturing conditions, microstructural characteristics and mechanical properties, namely hardness, fracture toughness and wear resistance. Although it is considered to be one of the most stable composites in terms of industrial requirements, challenges have been faced in the areas and routes of manufacturing, and consolidation with a desired set of mechanical properties via different processing techniques. In the field of cemented carbides, the understanding of the processes such as powder refinement and consolidation or sintering, contributing to the mechanical properties is critical. The aim of this project was to examine three different groups of powder size of Tungsten Carbide-Cobalt (WC-Co), which is the dominant compositional elements among all cemented carbides, and four consolidation techniques including plasma, microwave and conventional sintering, in order to understand the relationship between these processes and mechanical properties. This study started with analysing three different particle size for both Tungsten Carbide (WC) and Cobalt (Co), which then resulted into three different types of mixed powder samples based on their size. Once the compositions were made through either high or low energy ball milling, experiments proceeded to compaction and sintering stage. The chosen composition for the study was WC – 7.5 wt. % Co, which was kept constant, while particle size, sintering process, sintering temperature, pressure and other parameters were varied. The final and overall objective was to establish a three way relationship among particle size, processing routes and mechanical properties of WC – 7.5 wt. % Co. It was found that Pulse Plasma Sintering (PPS) method is the most successful in achieving excellent physical and mechanical properties including density (fully dense), hardness (2000 HV) and fracture toughness (15.3 MPa√m), and displays significantly improved microstructural behaviour in cemented carbides sintered at lower than conventional temperature, ensuring time and energy efficiency. Spark Plasma and Microwave Sintering were found to be the most efficient and effective after PPS in terms of mechanical properties, considering the entire particle size range and the other variable parameters. This thesis first outlines the basic understanding of cemented carbides, their fields of application, types, and processes that are involved during their manufacture. It then presents an overview article which is a chapter as well that presents an understanding of what has been done specifically in the areas of processing techniques, through powder refinement and consolidation highlighting the areas where challenges are faced. The mechanical properties along with certain microstructural aspects like grain growth and phases are also elaborated as part of this paper. The second paper… Advisors/Committee Members: Ghomashchi, Reza (advisor), Xie, Zonghan (advisor), School of Mechanical Engineering (school).

Subjects/Keywords: cemented carbide; sintering; microstructure; mechanical properties; Research by Publication

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rumman, M. R. (2016). Effect of particle size and sintering processes on mechanical properties of cemented carbides. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/115418

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rumman, Md Raihanuzzaman. “Effect of particle size and sintering processes on mechanical properties of cemented carbides.” 2016. Thesis, University of Adelaide. Accessed April 14, 2021. http://hdl.handle.net/2440/115418.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rumman, Md Raihanuzzaman. “Effect of particle size and sintering processes on mechanical properties of cemented carbides.” 2016. Web. 14 Apr 2021.

Vancouver:

Rumman MR. Effect of particle size and sintering processes on mechanical properties of cemented carbides. [Internet] [Thesis]. University of Adelaide; 2016. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/2440/115418.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rumman MR. Effect of particle size and sintering processes on mechanical properties of cemented carbides. [Thesis]. University of Adelaide; 2016. Available from: http://hdl.handle.net/2440/115418

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Nelson Mandela Metropolitan University

28. Davoren, Brandon Hilton. Tribocorrosion properties of friction stir welded and laser welded titanium alloy.

Degree: Faculty of Science, 2017, Nelson Mandela Metropolitan University

URL: http://hdl.handle.net/10948/33250

► Titanium alloy Ti6Al4V has extensive uses in aerospace, dentistry and the biomedical industry. When used in these applications there is often a need to weld… (more)

▼ Titanium alloy Ti6Al4V has extensive uses in aerospace, dentistry and the biomedical industry. When used in these applications there is often a need to weld two or more pieces of titanium alloy together. This can be done by either friction stir weld or laser weld methods. These welded regions are often exposed to corrosive environments in addition to factors such as induced additional mechanical wear. Thus to accurately report on the viability of the material in a specific application, the corrosion, wear and their synergistic effects need to be studied. Friction stir welding, which is a well-suited method for joining plates of Ti6Al4V, creates regions in the material that are affected differently. These regions can be described as the parent material, advancing side, retreating side and the weld zone. The tribological properties of the different friction stir weld regions were analysed in air using different loads, frequencies, experimental duration and surrounding environments. When the applied load was increased some of the weld regions showed an increase in the specific wear rate. For example, the weld zone region showed a decrease when compared to the parent material. In this tribology study the effect of the counter material was evaluated. E52100, Si3N4, SS 316 and alumina counter materials were used in the test procedure which was conducted in air on the weld regions. The parent material was found to have the highest average specific wear rates with the four counter materials when compared to the weld zone samples. The regions affected by the friction stir weld process all showed, on average, lower specific wear rates than the parent material. For the various tested samples, the coefficient of friction and material compatibility that was found to be the most stable, was the alumina ball. Owing to this as well as its chemical stability, alumina was determined to be the best material for further tribocorrosion studies. The friction stir welded samples, that were cut from a cross section of a friction stir weld plate, were analyzed in 3.5% NaCl and dilute Harrison’s solution respectively. The effect of wear on the electrochemical properties was studied under open circuit voltage (OCV) and fixed 0.2 V and 0.4 V applied potential conditions respectively. The effect of wear on the corrosion properties was studied using potentiodynamic polarization. From analyzing the friction stir weld regions in both a wear and wear-free environment, the synergistic properties, namely the effect of wear on corrosion and the effect of corrosion on wear, were able to be calculated. The first electrochemical study was performed under OCV conditions. In the presence of applied wear, the open circuit potential of the friction stir weld samples, in both 3.5% NaCl and dilute Harrison’s solution, was found to decrease from the initial stabilized value. Of interest was the rate at which the OCV recovered. It was found to follow a second order repassivation growth model which was explained in terms of an initial film growth stage, followed…

Subjects/Keywords: Chemistry, Technical – Research; Materials – Mechanical properties; Aluminum alloys

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Davoren, B. H. (2017). Tribocorrosion properties of friction stir welded and laser welded titanium alloy. (Thesis). Nelson Mandela Metropolitan University. Retrieved from http://hdl.handle.net/10948/33250

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Davoren, Brandon Hilton. “Tribocorrosion properties of friction stir welded and laser welded titanium alloy.” 2017. Thesis, Nelson Mandela Metropolitan University. Accessed April 14, 2021. http://hdl.handle.net/10948/33250.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Davoren, Brandon Hilton. “Tribocorrosion properties of friction stir welded and laser welded titanium alloy.” 2017. Web. 14 Apr 2021.

Vancouver:

Davoren BH. Tribocorrosion properties of friction stir welded and laser welded titanium alloy. [Internet] [Thesis]. Nelson Mandela Metropolitan University; 2017. [cited 2021 Apr 14]. Available from: http://hdl.handle.net/10948/33250.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Davoren BH. Tribocorrosion properties of friction stir welded and laser welded titanium alloy. [Thesis]. Nelson Mandela Metropolitan University; 2017. Available from: http://hdl.handle.net/10948/33250

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – San Diego

29. Savagatrup, Suchol. Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics.

Degree: Chemical Engineering, 2016, University of California – San Diego

URL: http://www.escholarship.org/uc/item/8p7441px

► The original vision of organic electronics comprises the use of organic conductors and semiconductors specifically designed to accommodate large strains to enable highly deformable and… (more)

▼ The original vision of organic electronics comprises the use of organic conductors and semiconductors specifically designed to accommodate large strains to enable highly deformable and mechanically robust devices for organic photovoltaics, biosensors, and electronic skins. However, mechanical properties of organic materials are often overlooked; as a result, many of these materials are unable to accommodate the mechanical stresses required for their intended applications. Thus, it is important to understand the parameters that govern mechanical properties of these materials. Chapter 1 provides an introduction to the characteristics, applications, and fabrications of stretchable electronics. The idea of intrinsically stretchable electronics comprising molecularly designs of semiconducting polymers is outlined. Chapter 2 focuses on the mechanical degradation and stability of organic solar cells. The key highlights are the importance of mechanical properties and mechanical effects on the viability of organic solar cells during manufacture and in operational environment. Chapter 3 and Appendix A investigate the effects of the length of the alkyl side chains in poly(3-alkylthiophenes) on the deformability of the pure polymer films and their blends with fullerenes. Chapter 4, 5, and Appendix B provide studies on the inherent competition between good photovoltaic performance and mechanical compliance; a critical length of the alkyl side chains on the poly(3-alkylthiophene) allows for co-optimization of both photovoltaic and mechanical properties. In Chapter 6 and Appendix C, the effect of incompletely separated grades of electron acceptors on the mechanical deformability of organic solar cells is investigated in an effort to simultaneously improve the mechanical robustness of the organic solar cells and reduce the energy of production. Chapter 7 describes the plasticization of the common transparent electrode using common processing additives. Chapter 8, 9, and 10 investigate the mechanical properties of low-bandgap polymers as the function of the molecular structure and solid-state packing. Chapter 11 introduces a novel experimental method, photovoltaic mapping (PVMAP), which combines the use of non-damaging electrode and gradients in processing parameter to spatially map the photovoltaic properties of organic solar cells.

Subjects/Keywords: Chemical engineering; Nanotechnology; Conjugated Polymers; Mechanical Properties; Organic Electronics; Organic Solar Cells; Polymers; Stretchable Electronics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Savagatrup, S. (2016). Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics. (Thesis). University of California – San Diego. Retrieved from http://www.escholarship.org/uc/item/8p7441px

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Savagatrup, Suchol. “Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics.” 2016. Thesis, University of California – San Diego. Accessed April 14, 2021. http://www.escholarship.org/uc/item/8p7441px.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Savagatrup, Suchol. “Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics.” 2016. Web. 14 Apr 2021.

Vancouver:

Savagatrup S. Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics. [Internet] [Thesis]. University of California – San Diego; 2016. [cited 2021 Apr 14]. Available from: http://www.escholarship.org/uc/item/8p7441px.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Savagatrup S. Semiconducting polymers for stretchable, ultra-flexible, and mechanically robust organic photovoltaics. [Thesis]. University of California – San Diego; 2016. Available from: http://www.escholarship.org/uc/item/8p7441px

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ryerson University

30. Macwan, Alpeshkumar. Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell.

Degree: 2012, Ryerson University

URL: https://digital.library.ryerson.ca/islandora/object/RULA%3A1843

► This study is aimed at identifying the change of residual stresses in suspension plasma sprayed (SPS) 8 mol% YSZ electrolytes on top of porous stainless… (more)

Subjects/Keywords: Solid oxide fuel cells – Materials; Residual stresses – Measurement; Ceramic materials – Mechanical properties; Microstructure

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Macwan, A. (2012). Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell. (Thesis). Ryerson University. Retrieved from https://digital.library.ryerson.ca/islandora/object/RULA%3A1843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Macwan, Alpeshkumar. “Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell.” 2012. Thesis, Ryerson University. Accessed April 14, 2021. https://digital.library.ryerson.ca/islandora/object/RULA%3A1843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Macwan, Alpeshkumar. “Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell.” 2012. Web. 14 Apr 2021.

Vancouver:

Macwan A. Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell. [Internet] [Thesis]. Ryerson University; 2012. [cited 2021 Apr 14]. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Macwan A. Residual Stresses in Suspension Plasma Sprayed Electrolytes in Metal-Supported solid Oxide Fuel Cell. [Thesis]. Ryerson University; 2012. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations