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University of Alberta
1.
Appah, Yvonne A.
Securement of the Indwelling Urinary Catheter: A Prevalence
Study.
Degree: Master of Nursing, Faculty of Nursing, 2013, University of Alberta
URL: https://era.library.ualberta.ca/files/g445cf038
► Experts in urology recommend stabilizing of indwelling urinary catheters (IUCs) following urethral catheterization to prevent urethral injury and patient discomfort. However, catheter securement practices have…
(more)
▼ Experts in urology recommend stabilizing of indwelling
urinary catheters (IUCs) following urethral catheterization to
prevent urethral injury and patient discomfort. However, catheter
securement practices have not been well studied and there is some
evidence that practices are not consistent. In this one-day
prevalence study, conducted at one tertiary care hospital in
Edmonton, Alberta, data was collected on 21 medical and surgical
units. Convenience sampling was used to obtain adult participants
with urinary catheters who could provide written informed consent
or had a family caregiver available for proxy consent. From a total
of 72 patients with IUCs 44 participated; 39% (17) were from
medicine and 61% (27) from surgery units. The overall prevalence of
catheter securement was 18% (n=8/44). The results from this study
demonstrate that stabilizing urethral catheters is not a common
occurrence for individuals at the centre surveyed. Further research
is needed to explore factors that impact securement
practices.
Subjects/Keywords: catheter securement; urethral catheter; catheter fixation; indwelling urinary catheter; catheter care
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APA (6th Edition):
Appah, Y. A. (2013). Securement of the Indwelling Urinary Catheter: A Prevalence
Study. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/g445cf038
Chicago Manual of Style (16th Edition):
Appah, Yvonne A. “Securement of the Indwelling Urinary Catheter: A Prevalence
Study.” 2013. Masters Thesis, University of Alberta. Accessed April 19, 2021.
https://era.library.ualberta.ca/files/g445cf038.
MLA Handbook (7th Edition):
Appah, Yvonne A. “Securement of the Indwelling Urinary Catheter: A Prevalence
Study.” 2013. Web. 19 Apr 2021.
Vancouver:
Appah YA. Securement of the Indwelling Urinary Catheter: A Prevalence
Study. [Internet] [Masters thesis]. University of Alberta; 2013. [cited 2021 Apr 19].
Available from: https://era.library.ualberta.ca/files/g445cf038.
Council of Science Editors:
Appah YA. Securement of the Indwelling Urinary Catheter: A Prevalence
Study. [Masters Thesis]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/g445cf038

Delft University of Technology
2.
Van Lith, J.Y. (author).
Multi-Selective Catheter with Two Deflectable Segments.
Degree: 2012, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:ded39193-9ae4-42c3-99ec-41509865398f
► Endovascular interventions are a type of minimally invasive surgery used to diagnose and treat vascular conditions. Long, thin and flexible medical devices like catheters are…
(more)
▼ Endovascular interventions are a type of minimally invasive surgery used to diagnose and treat vascular conditions. Long, thin and flexible medical devices like catheters are percutaneously inserted into the blood vessels. Time-action analysis has shown that the navigation of the medical devices from the access to the destination site is inefficient, thereby increasing the inherent risks and costs of endovascular interventions. A new steerable catheter with two deflectable segments may benefit the procedure by reducing the number of device exchanges while speeding up the process. The new catheter is designed for navigation to the arteries in the legs. Currently, multiple selective catheters are used consuctively to first cross the aortic bifurcation and then navigate down the leg. The new steerable catheter is designed to three commonly used selective catheters. A handle is also designed to actuate the two deflectable segments. A prototype is built and experimentally evaluated. The catheter has the required axial and rotational stiffness, but lacks the required bending elasticity. The deflectable segments can successfully be actuated into the desired geometries. However, the bending elasticity must be improved before conclusive evidence can be found that the catheter can replace the selected conventional catheters. Experiments within a vascular model show promising initial results.
BMD
BioMechanical Engineering
Mechanical, Maritime and Materials Engineering
Advisors/Committee Members: Dankelman, J. (mentor), Dobbelsteen, J.J. (mentor), Clogenson, H.C.M. (mentor).
Subjects/Keywords: steerable catheter
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APA (6th Edition):
Van Lith, J. Y. (. (2012). Multi-Selective Catheter with Two Deflectable Segments. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:ded39193-9ae4-42c3-99ec-41509865398f
Chicago Manual of Style (16th Edition):
Van Lith, J Y (author). “Multi-Selective Catheter with Two Deflectable Segments.” 2012. Masters Thesis, Delft University of Technology. Accessed April 19, 2021.
http://resolver.tudelft.nl/uuid:ded39193-9ae4-42c3-99ec-41509865398f.
MLA Handbook (7th Edition):
Van Lith, J Y (author). “Multi-Selective Catheter with Two Deflectable Segments.” 2012. Web. 19 Apr 2021.
Vancouver:
Van Lith JY(. Multi-Selective Catheter with Two Deflectable Segments. [Internet] [Masters thesis]. Delft University of Technology; 2012. [cited 2021 Apr 19].
Available from: http://resolver.tudelft.nl/uuid:ded39193-9ae4-42c3-99ec-41509865398f.
Council of Science Editors:
Van Lith JY(. Multi-Selective Catheter with Two Deflectable Segments. [Masters Thesis]. Delft University of Technology; 2012. Available from: http://resolver.tudelft.nl/uuid:ded39193-9ae4-42c3-99ec-41509865398f

Delft University of Technology
3.
Schouten, Luuk (author).
Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation.
Degree: 2017, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:e2faaaf0-4bb5-40d5-b5ff-80aa8a7d2f1e
► Aortic stenosis is one of the most serious heart valve diseases and is the result of calcification of the aortic valve leaflets. This calcification is…
(more)
▼ Aortic stenosis is one of the most serious heart valve diseases and is the result of calcification of the aortic valve leaflets. This calcification is irreversible and affect the functionality of the heart valves. The only treatment is an aortic valve replacement. The trend in heart valve replacement is moving from open heart surgery towards minimally invasive techniques where a heart valve prosthesis is placed over the native aortic valve, called the TAVI procedure. A crimped stent that contains a heart valve prosthesis is pushed upwards through the femoral access route with a delivery
catheter. This prosthesis is placed in the aortic annulus and wedged over the native valve. The positioning of the heart valve prosthesis is important for the success of the procedure and durability of the prosthesis. A coaxial placement to the aortic annulus in the center of the aorta lumen is the target during this positioning of the prosthesis. The Medtronics and Edwards delivery systems, that are currently used, only have the possibility to be steered with a maximum of 1 rotation, providing an alignment with the aortic annulus in the frontal plane of the body. The rotation to provide the alignment in the sagittal plane is lacking. This report will focus on the question if extra steerability of the delivery system will provide a better positioning of the tip of the delivery system, which in the end, will position the heart valve prosthesis. The Edwards delivery system will be reverse engineered to look at the current mechanisms that are used to provide the rotation in the frontal plane. Subsequently, two experiments are performed to select the best configuration for the modification on the tip of the delivery system. Ultimately, the designed prototype will be validated with two tests to answer the research question if the extra steerability will provide a better positioning. The prototype is validated by comparing the positioning of the Medtronics and Edwards delivery system with the prototype during an experiment where the three systems have to be maneuvered to a predefined position in an aorta model of glass. This predefined position represents the center of the aorta lumen in a coaxial orientation. Two rotations and the xyz-coordinations of the tip will be measured by an Aurora NDI system and the results will be compared. It showed that the prototype provided a bigger reach within the aorta lumen and a had a bigger domain of angles in which the tip could be orientated than the prototype. Moreover, the prototype provided a better alignment in the sagittal and frontal plane with regards to the reference point. The research only focused on the positioning of the tip and didn’t take the deployment of the heart valve prosthesis into account. Further development of the prototype is needed to make it useful for the TAVI procedure. In addition, more research is needed to validate the prototype in a dynamic environment that represents the reality with blood flow and more…
Advisors/Committee Members: van den Dobbelsteen, John (mentor), Dankelman, Jenny (graduation committee), Mugge, Ruth (graduation committee), Delft University of Technology (degree granting institution).
Subjects/Keywords: TAVI; Steerable; Catheter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schouten, L. (. (2017). Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:e2faaaf0-4bb5-40d5-b5ff-80aa8a7d2f1e
Chicago Manual of Style (16th Edition):
Schouten, Luuk (author). “Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation.” 2017. Masters Thesis, Delft University of Technology. Accessed April 19, 2021.
http://resolver.tudelft.nl/uuid:e2faaaf0-4bb5-40d5-b5ff-80aa8a7d2f1e.
MLA Handbook (7th Edition):
Schouten, Luuk (author). “Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation.” 2017. Web. 19 Apr 2021.
Vancouver:
Schouten L(. Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation. [Internet] [Masters thesis]. Delft University of Technology; 2017. [cited 2021 Apr 19].
Available from: http://resolver.tudelft.nl/uuid:e2faaaf0-4bb5-40d5-b5ff-80aa8a7d2f1e.
Council of Science Editors:
Schouten L(. Catheter with Improved steerability for the TAVI Procedure: Design, Development and Validation. [Masters Thesis]. Delft University of Technology; 2017. Available from: http://resolver.tudelft.nl/uuid:e2faaaf0-4bb5-40d5-b5ff-80aa8a7d2f1e

University of Ottawa
4.
Ikesaka, Rick.
The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters.
Degree: MSc, Médecine / Medicine, 2021, University of Ottawa
URL: http://dx.doi.org/10.20381/ruor-26176
► Venous thromboembolism (VTE) is a common disorder which causes significant morbidity and mortality. Upper extremity deep vein thrombosis(UEDVT) is a relatively understudied subtype of VTE…
(more)
▼ Venous thromboembolism (VTE) is a common disorder which causes significant morbidity and mortality. Upper extremity deep vein thrombosis(UEDVT) is a relatively understudied subtype of VTE which is commonly associated with central venous catheters, cancer, and thrombophilia.
The goal of this project was to better characterize the risk of UEDVT and to design and execute a pilot study that will demonstrate the efficacy of a strategy preventing the occurrence of VTE in a high-risk population for UEDVT.
This M.Sc project, was conducted in three parts.
Chapter 1 of the thesis outlines a systematic review of the literature which assessed the risk of VTE in UEDVT patients by search for and including data from studies with patients with prospectively enrolled symptomatic UEDVT.
Chapter 2 describes the development and final protocol of the TRIM-Line pilot study, a randomized open-label study comparing 90 days of rivaroxaban 10mg po daily against the current standard of care (observation) in patients with active cancer and central venous catheters, two known risk factors for VTE.
Finally in Chapter 3 the TRIM-Line study was executed as a pilot trial involving The Ottawa Hospital and the Juravinski Cancer Centre located in Hamilton. The study was conducted from March 2019 until February 2020. 105 patients underwent randomization at the two Canadian centres. The study met its prespecified feasibility endpoint average enrolment rate of 7.5 per month (95% CI:4.56, 10.44) at the coordinating Ottawa Hospital site and 2.0 per month (95% CI:0.87, 3.13) for the Juravinski Cancer Centre site. The randomized controlled trial met its enrollment targets and demonstrated that a full scale randomized controlled trial on the topic of prevention of cancer associated venous thromboembolism is feasible.
Advisors/Committee Members: Carrier, Marc (supervisor).
Subjects/Keywords: Thrombosis; Cancer; Catheter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ikesaka, R. (2021). The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters. (Masters Thesis). University of Ottawa. Retrieved from http://dx.doi.org/10.20381/ruor-26176
Chicago Manual of Style (16th Edition):
Ikesaka, Rick. “The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters.” 2021. Masters Thesis, University of Ottawa. Accessed April 19, 2021.
http://dx.doi.org/10.20381/ruor-26176.
MLA Handbook (7th Edition):
Ikesaka, Rick. “The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters.” 2021. Web. 19 Apr 2021.
Vancouver:
Ikesaka R. The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters. [Internet] [Masters thesis]. University of Ottawa; 2021. [cited 2021 Apr 19].
Available from: http://dx.doi.org/10.20381/ruor-26176.
Council of Science Editors:
Ikesaka R. The Risk of Upper Extremity Deep Vein Thrombosis and Primary Thromboprophylaxis with Low Dose Rivaroxaban in Oncology Patients with Central Venous Catheters. [Masters Thesis]. University of Ottawa; 2021. Available from: http://dx.doi.org/10.20381/ruor-26176
5.
Liu, Taoming.
A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE.
Degree: PhD, EECS - Electrical Engineering, 2017, Case Western Reserve University School of Graduate Studies
URL: http://rave.ohiolink.edu/etdc/view?acc_num=case1484654444253783
► This thesis focuses on design, modeling, and analysis of a magnetically actuated robotic intravascular catheter for performing atrial fibrillation ablation under magnetic resonance imaging guidance.…
(more)
▼ This thesis focuses on design, modeling, and analysis
of a magnetically actuated robotic intravascular
catheter for
performing atrial fibrillation ablation under magnetic resonance
imaging guidance. Specifically:A three dimensional deflection model
of a steerable
catheter in free space is proposed and
experimentally validated using a hardware prototype. In the
proposed method, the
catheter is modeled as a series of finite
segments. For each finite segment, a quasi-static torque-deflection
equilibrium equation is calculated using the beam theory. By using
the deflection displacements and torsion angles, the kinematic
model of the
catheter is derived. A Jacobian-based iterative
inverse kinematics method for controlling the steerable
catheter is
presented. The repeatability and accuracy of the open-loop control
of the
catheter system performing complex geometric trajectories
using this inverse kinematics method is experimentally evaluated.
The proposed three dimensional kinematic model is extended to
incorporate the
catheter-surface contact by taking contact forces
and torques into account. A systematic approach to the design
optimization of a magnetically-actuated steerable
catheter for
atrial fibrillation ablation in the left atrium, is proposed. The
study investigates the relationship between the
catheter material
and the
catheter's steering performance and evaluates the design
optimization of the electromagnetic coils, such as the optimal
winding turns for the coils, the optimal size for the side coils
and the optimal locations of the coil sets on the
catheter. The
selected design is validated on a simulated atrial fibrillation
ablation in a realistic left atrium model. The simulation verifies
that the
catheter is successfully able to reach every target on the
circumferential lesions.
Advisors/Committee Members: Cavusoglu, Murat (Committee Chair).
Subjects/Keywords: Robotics; Robots; Robotic Catheter; Magnetically-Actuated Catheter; Atrial Fibrillation Ablation; Real-time MRI Guidance; Robotic Intravascular Catheter; Catheter Deflection Model; Iterative Inverse Kinematics; Catheter-Surface Contact Model; Catheter Design Optimization
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Liu, T. (2017). A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE. (Doctoral Dissertation). Case Western Reserve University School of Graduate Studies. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=case1484654444253783
Chicago Manual of Style (16th Edition):
Liu, Taoming. “A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE.” 2017. Doctoral Dissertation, Case Western Reserve University School of Graduate Studies. Accessed April 19, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=case1484654444253783.
MLA Handbook (7th Edition):
Liu, Taoming. “A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE.” 2017. Web. 19 Apr 2021.
Vancouver:
Liu T. A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE. [Internet] [Doctoral dissertation]. Case Western Reserve University School of Graduate Studies; 2017. [cited 2021 Apr 19].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1484654444253783.
Council of Science Editors:
Liu T. A MAGNETICALLY-ACTUATED ROBOTIC CATHETER FOR ATRIAL
FIBRILLATION ABLATION UNDER REAL-TIME MAGNETIC RESONANCE IMAGING
GUIDANCE. [Doctoral Dissertation]. Case Western Reserve University School of Graduate Studies; 2017. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=case1484654444253783
6.
伊藤, 治男.
Left ventricular volumetric conductance catheter for rats.
Degree: 博士(医学), 1999, Okayama University / 岡山大学
URL: http://ousar.lib.okayama-u.ac.jp/1891
Subjects/Keywords: conductance catheter
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APA ·
Chicago ·
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Export
to Zotero / EndNote / Reference
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APA (6th Edition):
伊藤, . (1999). Left ventricular volumetric conductance catheter for rats. (Thesis). Okayama University / 岡山大学. Retrieved from http://ousar.lib.okayama-u.ac.jp/1891
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
伊藤, 治男. “Left ventricular volumetric conductance catheter for rats.” 1999. Thesis, Okayama University / 岡山大学. Accessed April 19, 2021.
http://ousar.lib.okayama-u.ac.jp/1891.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
伊藤, 治男. “Left ventricular volumetric conductance catheter for rats.” 1999. Web. 19 Apr 2021.
Vancouver:
伊藤 . Left ventricular volumetric conductance catheter for rats. [Internet] [Thesis]. Okayama University / 岡山大学; 1999. [cited 2021 Apr 19].
Available from: http://ousar.lib.okayama-u.ac.jp/1891.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
伊藤 . Left ventricular volumetric conductance catheter for rats. [Thesis]. Okayama University / 岡山大学; 1999. Available from: http://ousar.lib.okayama-u.ac.jp/1891
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta
7.
Ayranci, Cagri.
Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters.
Degree: PhD, Department of Mechanical Engineering, 2010, University of Alberta
URL: https://era.library.ualberta.ca/files/cpv63g0321
► Two-dimensionally (2D) braided tubular composites have been utilized in a wide range of applications including medical equipment such as braided stents and catheters. Catheters are…
(more)
▼ Two-dimensionally (2D) braided tubular composites have
been utilized in a wide range of applications including medical
equipment such as braided stents and catheters. Catheters are long
flexible tubes used in catheterization procedures, such as
angiography and ablations. In this thesis, angiographic catheters
were specifically targeted; which are referred as “catheters” for
the remaining of the document. Catheters are typically used with
guidewires which provide structural support to the often low
rigidity catheters. In some catheterization procedures, it may be
beneficial to use a 2D braided catheter for increased control and
maneuverability in the body. The 2D braided catheter, if designed
properly, may provide all the required rigidities for a successful
procedure and decrease the dependency to the guidewire compared to
conventional catheters. Hence, use of 2D braided catheters may
decrease the procedure time, may provide superior control of the
device due to its design, and may also decrease the inherent
patient discomfort. A thorough understanding of 2D braided
composites is of absolute necessity considering the delicate use of
medical equipment, such as catheters, in the human body. The aim of
this PhD thesis is to address the shortcomings of the available
models in the literature by developing an analytical model
geometrically consistent with small braided tubular structures and
provide all the necessary tools possible to design a target
specific braided catheter. An analytical model that accounts for
the effect of diameter of a braided tubular product on the elastic
properties, needed for catheter design, was developed. Parametric
studies were conducted to highlight the effects of the change in
radius on elastic properties of braided composites. Case studies
that underline the important geometrical parameters that affect
predictions were conducted and findings discussed. Effect of
increased undulation length on elastic properties of braided
composites was also investigated. The findings were compared to
experimental work using three different fiber/matrix system
composites. As predicted by the model, a decrease in the properties
was observed experimentally; however, this decrease was found to be
more important than predicted. Possible reasons for this behavior
are discussed in the view of composite materials and geometrical
factors. The experimental findings of the open-mesh composites were
also used to further validate a regression based model available in
the literature. Lower linearity limit values for the regression
based model were calculated for longitudinal elastic and shear
moduli predictions.
Subjects/Keywords: analytical; braiding; composite; catheter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ayranci, C. (2010). Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/cpv63g0321
Chicago Manual of Style (16th Edition):
Ayranci, Cagri. “Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters.” 2010. Doctoral Dissertation, University of Alberta. Accessed April 19, 2021.
https://era.library.ualberta.ca/files/cpv63g0321.
MLA Handbook (7th Edition):
Ayranci, Cagri. “Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters.” 2010. Web. 19 Apr 2021.
Vancouver:
Ayranci C. Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters. [Internet] [Doctoral dissertation]. University of Alberta; 2010. [cited 2021 Apr 19].
Available from: https://era.library.ualberta.ca/files/cpv63g0321.
Council of Science Editors:
Ayranci C. Predicting the Elastic Properties of Two Dimensionally
Braided Tubular Composite Structures Towards the Design of
Braid-Reinforced Polymer Medical Catheters. [Doctoral Dissertation]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/cpv63g0321

Liberty University
8.
Harris-Hall, Janice LaVerne.
Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review.
Degree: 2020, Liberty University
URL: https://digitalcommons.liberty.edu/doctoral/2554
► The role of Central Venous Catheters (CVC) is significant for the End-Stage Renal Disease (ESRD) population. The placement of the CVC for a HD (HD)…
(more)
▼ The role of Central Venous Catheters (CVC) is significant for the End-Stage Renal Disease (ESRD) population. The placement of the CVC for a HD (HD) patient is not only necessary, but life-sustaining. CVCs are usually placed for an emergent HD treatment, while awaiting a permanently placed arteriovenous fistula or graft (AVF/AVG), or when the permanent access becomes non-functioning. There are multiple risk factors related to having a CVC placed, the most predominant complication being catheter line-associated bloodstream infections (CLABSIs). Studies have shown that implementing a CVC prevention bundle was associated with a significant reduction in the CLABSI rates within the HD population. Implementing and examining the efficacy of best evidence-based practices to determine whether infection rates decrease in the ESRD population with a prevention bundle intervention, was the aim of this integrative review. Having the ability to control infection in ESRD patients is a challenging task for healthcare providers, especially because catheters are often manipulated during HD treatments, and ESRD patients are already immunocompromised.
Subjects/Keywords: Catheter Related Bloodstream Infection; Nursing
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Harris-Hall, J. L. (2020). Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review. (Doctoral Dissertation). Liberty University. Retrieved from https://digitalcommons.liberty.edu/doctoral/2554
Chicago Manual of Style (16th Edition):
Harris-Hall, Janice LaVerne. “Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review.” 2020. Doctoral Dissertation, Liberty University. Accessed April 19, 2021.
https://digitalcommons.liberty.edu/doctoral/2554.
MLA Handbook (7th Edition):
Harris-Hall, Janice LaVerne. “Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review.” 2020. Web. 19 Apr 2021.
Vancouver:
Harris-Hall JL. Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review. [Internet] [Doctoral dissertation]. Liberty University; 2020. [cited 2021 Apr 19].
Available from: https://digitalcommons.liberty.edu/doctoral/2554.
Council of Science Editors:
Harris-Hall JL. Improving Central Venous Catheter Infection Rates Through The Use of A Bundle: An Integrative Review. [Doctoral Dissertation]. Liberty University; 2020. Available from: https://digitalcommons.liberty.edu/doctoral/2554

Harvard University
9.
Barber, Lauren Ashley.
Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy.
Degree: Doctor of Medicine, 2017, Harvard University
URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41973450
► Purpose: To present a catheter segmentation method for use with 3T MR-guided brachytherapy and validate its results on a phantom and in clinical cases. We…
(more)
▼ Purpose: To present a catheter segmentation method for use with 3T MR-guided brachytherapy and validate its results on a phantom and in clinical cases. We report a novel image-processing method for catheter segmentation that extends the distal catheter tip, interactively provided by the physician, to its proximal end, using catheter geometry, appearance, and behavior in MRI.
Methods: Comparisons were performed between results of iGyne and expert human segmentations on phantom and patient MRI. In phantom experiments, the maximum disagreement between automatic and manual MR segmentation, as computed using the Hausdorff distance (HD), was 1.5 mm, which is the same order as the MR image spatial resolution. The disagreement between automatic segmentation of MR images and “the ground truth” (which is manual segmentation of CT images) was 3.5mm. Based on the failure modes demonstrated by these initial studies, a second algorithm (NeedleFinder), guided by a catheter-specific mechanical model, performed segmentation using image features with a final quality control step to remove outliers or conflicting catheter trajectories.
Results: The initial segmentation method (iGyne) was applied to 10 interstitial brachytherapy patients, which included a total of 101 catheters. Compared with manual segmentations, the automatic method correctly segmented 93 out of 101 catheters, at an average rate of 0.3 seconds per catheter (correct defined as HD < 2mm, which is the catheter diameter). The mean Hausdorff error for the improved, mechanically-based algorithm (NeedleFinder) on a 54 patient, 760 catheter reference database was 1.49; 51 of the outliers deviated more than two catheter widths (3.4 mm) from the gold standard, corresponding to catheter identification accuracy of 93%. In a multi-user simulation experiment for evaluating RMS precision by simulating varying manually provided superior tip positions, 3σ maximum error was 2.44 mm.
Conclusions: These results suggest that the speed, precision, and accuracy of the proposed catheter segmentation method allow for technical and clinical feasibility. Future directions will continue to compare patient MRI and CT to determine target doses and dosages to organs-at-risk. If, according to published guidelines, the MR-based dose and complication rate are significant improvements over those of CT, then a case will be made for performing MR-based treatments instead of CT.
Scholarly Project
Subjects/Keywords: Brachytherapy; Validation; Segmentation; Catheter; MRI
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APA ·
Chicago ·
MLA ·
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CSE |
Export
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APA (6th Edition):
Barber, L. A. (2017). Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy. (Doctoral Dissertation). Harvard University. Retrieved from http://nrs.harvard.edu/urn-3:HUL.InstRepos:41973450
Chicago Manual of Style (16th Edition):
Barber, Lauren Ashley. “Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy.” 2017. Doctoral Dissertation, Harvard University. Accessed April 19, 2021.
http://nrs.harvard.edu/urn-3:HUL.InstRepos:41973450.
MLA Handbook (7th Edition):
Barber, Lauren Ashley. “Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy.” 2017. Web. 19 Apr 2021.
Vancouver:
Barber LA. Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy. [Internet] [Doctoral dissertation]. Harvard University; 2017. [cited 2021 Apr 19].
Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41973450.
Council of Science Editors:
Barber LA. Validation of Catheter Segmentation for MR-Guided Gynecologic Cancer Brachytherapy. [Doctoral Dissertation]. Harvard University; 2017. Available from: http://nrs.harvard.edu/urn-3:HUL.InstRepos:41973450

University of Minnesota
10.
Ling, Xiaoyin.
Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study.
Degree: M.S.M.E., Mechanical Engineering, 2019, University of Minnesota
URL: http://hdl.handle.net/11299/202083
► Catheter-associated urinary tract infections (CAUTI) is among the most common hospital acquired infection [1], while medical students placing catheters could increase CAUTI risk four times…
(more)
▼ Catheter-associated urinary tract infections (CAUTI) is among the most common hospital acquired infection [1], while medical students placing catheters could increase CAUTI risk four times [2]. Therefore, a better understanding of the catheter insertion mechanical characteristics is needed to develop more realistic simulators for accurate clinical training. A custom-made Catheter Insertion Force Assessment Tool (+/- 0.25N absolute accuracy) and Position Acquisition System were used in male urethral catheterization studies on benchtop simulators (n=4) and cadaveric donors (n=5) to quantitatively examine the insertion force and 3D motion. Displacement-dependent effects resembling tissue stiffness appeared to dominate the force profile over rate-dependent effects such as viscous friction. In cadaveric studies, the average prostate region force was found to be higher than non-prostate region force. Average catheterization forces in simulators (8.1N) were roughly 45 percent higher than in donors (5.6N) when considering all data per insertion segment falling within 98 percentiles to diminish outlier effects.
Subjects/Keywords: Catheter Insertion Force; Urethral Catheterization
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APA ·
Chicago ·
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Export
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APA (6th Edition):
Ling, X. (2019). Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study. (Masters Thesis). University of Minnesota. Retrieved from http://hdl.handle.net/11299/202083
Chicago Manual of Style (16th Edition):
Ling, Xiaoyin. “Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study.” 2019. Masters Thesis, University of Minnesota. Accessed April 19, 2021.
http://hdl.handle.net/11299/202083.
MLA Handbook (7th Edition):
Ling, Xiaoyin. “Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study.” 2019. Web. 19 Apr 2021.
Vancouver:
Ling X. Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study. [Internet] [Masters thesis]. University of Minnesota; 2019. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/11299/202083.
Council of Science Editors:
Ling X. Mechanical Characteristics of Male Urethral Catheterization: Simulator and Cadaveric Donor Study. [Masters Thesis]. University of Minnesota; 2019. Available from: http://hdl.handle.net/11299/202083

Uppsala University
11.
Fjärstedt, Jenny.
Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus.
Degree: Applied Materials Sciences, 2016, Uppsala University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297294
► In this project, problems related to loss of free flow in central venous catheter and implanted subcutaneous ports have been investigated. The catheters investigated…
(more)
▼ In this project, problems related to loss of free flow in central venous catheter and implanted subcutaneous ports have been investigated. The catheters investigated in this project are intended for children with cancer diseases. The initial hypothesis was that the length, radius and curvature of the catheter would affect the flow. Two other things that can have a negative impact on the flow are if the catheter is squashed or kinked. Experiments and simulations have been performed in order to test the hypothesis and investigate how a deformation of the catheter affects the flow. The results from the experiments and simulations show that the length and radius of the catheter have major impact on the pressure drop, and hence the flow. The curvature of the catheter has less impact on the flow as long as the catheter is not kinked. Experiments with squashed catheters show a decrease in outlet pressure with a decrease of the catheter lumen.
Denna projektrapport ämnar undersöka problem relaterade till fritt flöde i centrala venkatetrar och inopererade subkutana portar. Katetrarna som testats i detta projekt är till för barn med cancersjukdomar. Den ursprungliga hypotesen var att längden, radien och krökningen hos katetern påverkar flödet. Ytterligare två saker som skulle kunna ha negativ effekt på flödet är om katetern är klämd eller veckad. För att testa hypotesen om hur deformationer av katetern påverkar flödet har experiment och simuleringar utförts. Resultaten från experiment och simuleringar visar att kateterns längd och radie har störst effekt på tryckfallet och därmed flödet. Krökningen på katetern har mindre betydelse, så länge katetern inte är veckad. Experiment med klämd kateter visar att utloppstrycket minskar med minskad kateterlumen.
Subjects/Keywords: CVC; SVP; Catheter; Catheter Related Problems; Pediatric Oncology; Fluid Dynamics
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
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APA (6th Edition):
Fjärstedt, J. (2016). Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus. (Thesis). Uppsala University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297294
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Fjärstedt, Jenny. “Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus.” 2016. Thesis, Uppsala University. Accessed April 19, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297294.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Fjärstedt, Jenny. “Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus.” 2016. Web. 19 Apr 2021.
Vancouver:
Fjärstedt J. Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus. [Internet] [Thesis]. Uppsala University; 2016. [cited 2021 Apr 19].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297294.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Fjärstedt J. Catheter Related Problems in Pediatric Oncology Treatment : A Technical Investigation Performed at Uppsala Akademsika Sjukhus. [Thesis]. Uppsala University; 2016. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-297294
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology
12.
De Lat, B. (author).
Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model.
Degree: 2014, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:8d3b32c2-3658-4e0d-96ee-99d81e622505
► Background: An ablation catheter with integrated high-frequency single element ultrasound transducers has been developed by Philips Research, which makes it possible to assess tissue-depth and…
(more)
▼ Background: An ablation catheter with integrated high-frequency single element ultrasound transducers has been developed by Philips Research, which makes it possible to assess tissue-depth and lesion formation in real-time. The interpretation of the acquired ultrasound M-mode images is difficult due to a combination of cardiac motion and motion of the catheter itself. Objective The aim of this study is to develop and validate a simulation model that includes catheter and tissue motion and use this as a tool to gain insights in the effects of catheter motion on M-mode images and corresponding velocity profiles. Method A 2D simulation model, of a moving catheter with three integrated ultrasound transducers that observe contracting tissue, was developed. Comparison of simulated data with real ultrasound data was performed, among other tests, to validate the 2D simulation model. Validation criteria were based on predefined requirements. The validated simulation model was used to generate seventeen different output datasets varying with the frequency and amplitude of the cardiac \& catheter motion input signals. These datasets were used to analyse the effect of catheter motion on M-mode images and corresponding velocity profiles. Results The validation tests imply that the simulated data can serve as reliable replacements for real ultrasound data. Findings from the analysis of the simulated data suggest that cardiac velocity is underestimated when the catheter angle deviates from its perpendicular state in relation to the tissue and is overestimated when the catheter angle moves back to its perpendicular state. Moreover, when catheter motion dominates over cardiac motion the cardiac velocity may be estimated in the opposite direction as the actual direction of cardiac motion. Conclusion The validation tests insinuate that the simulation model meets the predefined requirements. The simulation increases understanding of the relation between catheter \& cardiac motion in M-mode images. The information that can be derived from an M-mode image can be used to estimate if catheter motion is dominating over cardiac motion. Furthermore, the findings obtained within this study can be used to evaluate if the estimated direction of the velocity of cardiac motion is correct and if the cardiac velocity is under- or overestimated.
BME
BioMechanical Engineering
Mechanical, Maritime and Materials Engineering
Advisors/Committee Members: Dankelman, J. (mentor), Tuijthof, G.J.M. (mentor).
Subjects/Keywords: catheter ablation; ultrasound; catheter motion; M-mode interpretation; velocity profile
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
De Lat, B. (. (2014). Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:8d3b32c2-3658-4e0d-96ee-99d81e622505
Chicago Manual of Style (16th Edition):
De Lat, B (author). “Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model.” 2014. Masters Thesis, Delft University of Technology. Accessed April 19, 2021.
http://resolver.tudelft.nl/uuid:8d3b32c2-3658-4e0d-96ee-99d81e622505.
MLA Handbook (7th Edition):
De Lat, B (author). “Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model.” 2014. Web. 19 Apr 2021.
Vancouver:
De Lat B(. Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model. [Internet] [Masters thesis]. Delft University of Technology; 2014. [cited 2021 Apr 19].
Available from: http://resolver.tudelft.nl/uuid:8d3b32c2-3658-4e0d-96ee-99d81e622505.
Council of Science Editors:
De Lat B(. Effect of catheter motion on ultrasound M-mode images and corresponding velocity profiles: Development and validation of a simulation model. [Masters Thesis]. Delft University of Technology; 2014. Available from: http://resolver.tudelft.nl/uuid:8d3b32c2-3658-4e0d-96ee-99d81e622505
13.
Francisca Jane Gomes de Oliveira.
AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos.
Degree: 2013, Universidade Federal do CearÃ; Programa de PÃs-GraduaÃÃo em Enfermagem; UFC; BR
URL: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11681
► nÃo hÃ
Os serviÃos de saÃde vÃm desenvolvendo aÃÃes e programas visando à qualificaÃÃo de seus processos de trabalho, com intuito de reduzir, prevenir…
(more)
▼ nÃo hÃ
Os serviÃos de saÃde vÃm desenvolvendo aÃÃes e programas visando à qualificaÃÃo de seus processos de trabalho, com intuito de reduzir, prevenir e eliminar deficiÃncias da qualidade e que tambÃm atendam Ãs necessidades e expectativas dos usuÃrios. Diferentes estratÃgias de avaliaÃÃes das prÃticas em saÃde tÃm sido adotadas, permitindo a identificaÃÃo das condiÃÃes em que as prÃticas assistenciais sÃo executadas. As infecÃÃes hospitalares constituem risco significativo à saÃde dos usuÃrios, e dentre estas, a infecÃÃo de corrente sanguÃnea relacionada ao cateter venoso central, dada a mortalidade a ela associada, especialmente quando acomete pacientes graves, internados em Unidade de Terapia Intensiva (UTI). Assim, este estudo objetivou avaliar a conformidade e nÃo conformidade das prÃticas de prevenÃÃo de infecÃÃo de corrente sanguÃnea relacionada ao cateter venoso central de curta permanÃncia (ICS-ACVC), por meio de indicadores clÃnicos
em uma Unidade de Terapia Intensiva. Trata-se de um estudo observacional, seccional, com abordagem quantitativa, estruturado a partir do âmanual de avaliaÃÃo das prÃticas de controle e prevenÃÃo de infecÃÃo hospitalarâ, realizado em um hospital da rede privada da cidade de Fortaleza/CearÃ. O universo do estudo foi composto pelas oportunidades de avaliaÃÃo das prÃticas selecionadas, realizadas pelos profissionais de saÃde (mÃdicos e profissionais de enfermagem) em pacientes internados na Unidade de Terapia Intensiva da instituiÃÃo e que passaram pelo procedimento de inserÃÃo do cateter venoso central de curta permanÃncia. A amostra baseou-se na conformidade esperada de 80%, com 2064 avaliaÃÃes distribuÃdas entre as prÃticas selecionadas, realizadas por meio da observaÃÃo direta ou registro em prontuÃrios. De acordo com os resultados encontrados, o indicador CSPI apresenta maior Ãndice de conformidade geral (62,5%), em seguida o indicador CSCM apresenta conformidade geral inferior Ã
ideal, com apenas 45%, entretanto, quando analisado cada item que compÃe este indicador, pode-se observar que essa inferioridade deve-se principalmente à nÃo realizaÃÃo da prÃticas de desinfecÃÃo de hubs e conectores com clorexidine 0,5% (17,5%) e troca de equipos e transdutores conforme recomendaÃÃo (13,5%). O indicador CSQI apresentou conformidade geral baixa (12,5%), devido à nÃo conformidade de algumas prÃticas como: uso de campo estÃril ampliado no momento de instalaÃÃo do cateter (30%) e o uso de antissÃptico de veÃculo alcoÃlico para preparo da pele antes da punÃÃo (37,5%). Jà o indicador HMSEL apresentou Ãndice de conformidade geral nulo. Conclui-se que, embora a avaliaÃÃo das prÃticas de registro de indicaÃÃo, tempo de permanÃncia, inserÃÃo percutÃnea, presenÃa de curativo oclusivo apÃs inserÃÃo do cateter, registro e periodicidade da troca do curativo do cateter tenham atingido conformidade similar ou superior à esperada de 80%, as demais prÃticas precisam de uma nova
elaboraÃÃo de estratÃgias que assegurem a adesÃo duradoura das prÃticas de controle e prevenÃÃo de ICS-ACVC, associada…
Advisors/Committee Members: Joselany Afio Caetano, Viviane Martins da Silva, Andrea Bezerra Rodrigues.
Subjects/Keywords: Central Venous Catheter; Catheter-Related Infections; Quality Indicators, Health Care; ENFERMAGEM
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APA ·
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MLA ·
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Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Oliveira, F. J. G. d. (2013). AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos. (Masters Thesis). Universidade Federal do CearÃ; Programa de PÃs-GraduaÃÃo em Enfermagem; UFC; BR. Retrieved from http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11681
Chicago Manual of Style (16th Edition):
Oliveira, Francisca Jane Gomes de. “AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos.” 2013. Masters Thesis, Universidade Federal do CearÃ; Programa de PÃs-GraduaÃÃo em Enfermagem; UFC; BR. Accessed April 19, 2021.
http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11681.
MLA Handbook (7th Edition):
Oliveira, Francisca Jane Gomes de. “AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos.” 2013. Web. 19 Apr 2021.
Vancouver:
Oliveira FJGd. AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos. [Internet] [Masters thesis]. Universidade Federal do CearÃ; Programa de PÃs-GraduaÃÃo em Enfermagem; UFC; BR; 2013. [cited 2021 Apr 19].
Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11681.
Council of Science Editors:
Oliveira FJGd. AvaliaÃÃo das prÃticas de prevenÃÃo e controle de infecÃÃo relacionadas ao cateter venoso central: indicadores clÃnicos. [Masters Thesis]. Universidade Federal do CearÃ; Programa de PÃs-GraduaÃÃo em Enfermagem; UFC; BR; 2013. Available from: http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11681
14.
Gelman, Daniel.
Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters.
Degree: 2019, University of Western Ontario
URL: https://ir.lib.uwo.ca/etd/6275
► Atrial fibrillation (AF), the most common and clinically significant heart rhythm disorder, is characterized by rapid and irregular electrical activity in the upper chambers resulting…
(more)
▼ Atrial fibrillation (AF), the most common and clinically significant heart rhythm disorder, is characterized by rapid and irregular electrical activity in the upper chambers resulting in abnormal contractions. Radiofrequency (RF) cardiac catheter ablation is a minimally invasive curative treatment that aims to electrically correct signal pathways inside the atria to restore normal sinus rhythm. Successful catheter ablation requires the complete and permanent elimination of arrhythmogenic signals by delivering transmural RF ablation lesions contiguously near and around key cardiac structures. These procedures are complex and technically challenging and, even when performed by the most skilled physician, nearly half of patients undergo repeat procedures due to incomplete elimination of the arrhythmogenic pathways. This thesis aims to incorporate innovative design to improve catheter stability and maneuverability through the development of robotic platforms that enable precise placement of reproducibly durable ablation lesions.
The first part of this thesis deals with the challenges to lesion delivery imposed by cardiorespiratory motion. One of the main determinants of the delivery of durable and transmural RF lesions is the ability to define and maintain a constant contact force between the catheter tip electrode and cardiac tissue, which is hampered by the presence of cardiorespiratory motion. To address this need, I developed and evaluated a novel catheter contact-force control device. The compact electromechanical add-on tool monitors catheter-tissue contact force in real-time and simultaneously adjusts the position of a force-sensing ablation catheter within a steerable sheath to compensate for the change in contact force. In a series of in vitro and in vivo experiments, the contact-force control device demonstrated an ability to: a) maintain an average force to within 1 gram of a set level; b) reduce contact-force variation to below 5 grams (2-8-fold improvement over manual catheter intervention); c) ensure the catheter tip never lost contact with the tissue and never approached dangerous force levels; and importantly, d) deliver reproducible RF ablation lesions regardless of cardiac tissue motion, which were of the same depth and volume as lesions delivered in the absence of tissue motion.
In the second part of the thesis, I describe a novel steerable sheath and catheter robotic navigation system, which incorporates the catheter contact-force controller. The robotic platform enables precise and accurate manipulation of a remote conventional steerable sheath and permits catheter-tissue contact-force control. The robotic navigation system was evaluated in vitro using a phantom that combines stationary and moving targets within an in vitro model representing a beating heart. An electrophysiologist used the robotic system to remotely navigate the sheath and catheter tip to select targets and compared the accuracy of reaching these targets performing the same tasks manually. Robotic intervention resulted in…
Subjects/Keywords: Catheter Ablation; Catheter Navigation; Radiofrequency Ablation; Contact-Force Control; Robotic Catheter Navigation System; Mechatronics; Linear Control Systems; Biomedical Devices and Instrumentation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gelman, D. (2019). Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters. (Thesis). University of Western Ontario. Retrieved from https://ir.lib.uwo.ca/etd/6275
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Gelman, Daniel. “Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters.” 2019. Thesis, University of Western Ontario. Accessed April 19, 2021.
https://ir.lib.uwo.ca/etd/6275.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Gelman, Daniel. “Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters.” 2019. Web. 19 Apr 2021.
Vancouver:
Gelman D. Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters. [Internet] [Thesis]. University of Western Ontario; 2019. [cited 2021 Apr 19].
Available from: https://ir.lib.uwo.ca/etd/6275.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Gelman D. Remote Navigation and Contact-Force Control of Radiofrequency Ablation Catheters. [Thesis]. University of Western Ontario; 2019. Available from: https://ir.lib.uwo.ca/etd/6275
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

UCLA
15.
HUI, SAI-HUNG.
Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine.
Degree: Clinical Research, 2013, UCLA
URL: http://www.escholarship.org/uc/item/3zn5q06g
► Central venous catheter (CVC) placement is one of the most common yet invasive procedures in hospitals associated with significant morbidity, mortality, and financial burden. There…
(more)
▼ Central venous catheter (CVC) placement is one of the most common yet invasive procedures in hospitals associated with significant morbidity, mortality, and financial burden. There is a paucity of literatures about graduating senior resident CVC performance in academic training hospitals. Baseline CVC performances of senior residents were measured, and the risk factors for poor performance were identified on a high fidelity CVC simulator. 28 of total 40 internal medicine senior residents within the last 2 months of residency training from 2010 and 2011 participated. 8 subjects forfeited the procedure before completion. Incorrect anatomical landmark identification and threading the guide-wire with excessive force on the first attempt were the two most predictive risk factors in predicting residents' poor CVC placement. Predictions and quantification of different patient safety outcome variables based on identified risk factors were made possible with various statistical models.
Subjects/Keywords: Medicine; Central venous catheter; Procedural Competence; Simulation
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APA ·
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MLA ·
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Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
HUI, S. (2013). Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine. (Thesis). UCLA. Retrieved from http://www.escholarship.org/uc/item/3zn5q06g
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
HUI, SAI-HUNG. “Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine.” 2013. Thesis, UCLA. Accessed April 19, 2021.
http://www.escholarship.org/uc/item/3zn5q06g.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
HUI, SAI-HUNG. “Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine.” 2013. Web. 19 Apr 2021.
Vancouver:
HUI S. Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine. [Internet] [Thesis]. UCLA; 2013. [cited 2021 Apr 19].
Available from: http://www.escholarship.org/uc/item/3zn5q06g.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
HUI S. Simulation Measurement and Prediction of Poor Central Line Performances by Graduating Senior Residents in Internal Medicine. [Thesis]. UCLA; 2013. Available from: http://www.escholarship.org/uc/item/3zn5q06g
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Utah
16.
Chapman, Radene Holt.
The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure.
Degree: MS;, Nursing;, 1982, University of Utah
URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1788/rec/1187
► This research determined the incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure (Pw). Routine Pw measurements were compared to…
(more)
▼ This research determined the incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure (Pw). Routine Pw measurements were compared to Pw's confirmed by the following more stringent criteria: a) Pw less than the mean pulmonary artery pressure (PAP); b) atrial waveform; c) free-flow through the catheter and blood vessel; and e) aspiration of capillary blood. One hundred and forty-three comparisons were made in 53 ICU ¦ patients being monitored with a Swan-Ganz catheter. Technical problems identified by the careful waveform analysis required to confirm the Pw were present in 41% of the initial measurements. These technical problems included: inadequate waveform (15%), poor dynamic response (20%), overinflation (4%), and suspect Pw (13%). Seventy-five percent of the technical problems were easily corrected by removing air bubbles, tightening loose connections, withdrawing or advancing the catheter 1 to 2 cm, increasing balloon volume, or irrigating the catheter. The remaining problems required catheter repositioning to resolve. The overall incidence of clinically significant errors (? 4 mmHg) was 17%. When a technical problem was present, the incidence of an error ? 4 mmHg was 23%. If the technical problem was not easily corrected and required catheter repositioning to resolve, the incidence of an error ? 4 mmHg was 53%. In the absence of technical problems, an error of ? 4 mmHg occurred in only 4% of the measurements. Aspiration of capillary blood was the only criterion which detected these errors. The criteria used to confirm the Pw requires careful waveform analysis (Criteria 1,2,3) and aspiration of capillary blood (Criteria 4). These criteria identify problems which can lead to errors in the Pw measurements. Identification and correction of technical problems, using waveform analysis improved the accuracy of the Pw measurement and can decrease the incidence of a clinical significant error from M% to only 4%. Waveform analysis, using Criteria 1, 2 and 3 should be done routinely in the critical care setting when measuring the Pw. Capillary blood aspiration (Criterion 4) offers only minimal improvement in the accuracy of the Pw measurement (4%) and is not warranted on a routine basis.
Subjects/Keywords: Nursing; Wedge Catheter
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Chapman, R. H. (1982). The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure. (Masters Thesis). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1788/rec/1187
Chicago Manual of Style (16th Edition):
Chapman, Radene Holt. “The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure.” 1982. Masters Thesis, University of Utah. Accessed April 19, 2021.
http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1788/rec/1187.
MLA Handbook (7th Edition):
Chapman, Radene Holt. “The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure.” 1982. Web. 19 Apr 2021.
Vancouver:
Chapman RH. The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure. [Internet] [Masters thesis]. University of Utah; 1982. [cited 2021 Apr 19].
Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1788/rec/1187.
Council of Science Editors:
Chapman RH. The incidence of clinically significant errors in the bedside measurement of pulmonary capillary wedge pressure. [Masters Thesis]. University of Utah; 1982. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/1788/rec/1187

Kyoto University / 京都大学
17.
Kato, Karin.
Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究.
Degree: 博士(医学), 2016, Kyoto University / 京都大学
URL: http://hdl.handle.net/2433/216176
;
http://dx.doi.org/10.14989/doctor.k19922
► Springer and European Journal of Clinical Microbiology and Infectious Diseases, 33, 2014, 1371-79, Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with…
(more)
▼ Springer and European Journal of Clinical Microbiology and Infectious Diseases, 33, 2014, 1371-79, Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter, K. Kato & Y. Matsumura & M. Yamamoto & M. Nagao & Y. Ito & S. Takakura & S. Ichiyama, figure number 2, original copyright notice is given to the publication in which the material was originally published, by adding; with kind permission from Springer Science and Business Media
新制・課程博士
甲第19922号
医博第4142号
Subjects/Keywords: Bacillus cereus; bloodstream infection; Seasonal trend; catheter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kato, K. (2016). Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究. (Thesis). Kyoto University / 京都大学. Retrieved from http://hdl.handle.net/2433/216176 ; http://dx.doi.org/10.14989/doctor.k19922
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kato, Karin. “Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究.” 2016. Thesis, Kyoto University / 京都大学. Accessed April 19, 2021.
http://hdl.handle.net/2433/216176 ; http://dx.doi.org/10.14989/doctor.k19922.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kato, Karin. “Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究.” 2016. Web. 19 Apr 2021.
Vancouver:
Kato K. Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究. [Internet] [Thesis]. Kyoto University / 京都大学; 2016. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/2433/216176 ; http://dx.doi.org/10.14989/doctor.k19922.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kato K. Seasonal trend and clinical presentation of Bacillus cereus bloodstream infection: association with summer and indwelling catheter : Bacillus cereus血流感染症発生の季節性変動と患者の臨床背景に関する研究. [Thesis]. Kyoto University / 京都大学; 2016. Available from: http://hdl.handle.net/2433/216176 ; http://dx.doi.org/10.14989/doctor.k19922
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan
18.
Hu, Andy 1985-.
DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY.
Degree: 2016, University of Saskatchewan
URL: http://hdl.handle.net/10388/7403
► The steerable catheters have demonstrated many advantages to overcome the limitations of the conventional catheters in the minimally invasive surgery. The motion and force transmission…
(more)
▼ The steerable catheters have demonstrated many advantages to overcome the limitations of the conventional catheters in the minimally invasive surgery. The motion and force transmission from the proximal end to distal tip of the
catheter have significant effects to the efficiency and safety of surgery. While the force information between the
catheter and the body (e.g., vessel) can be obtained by mounting sensors on the distal tip of the
catheter, this would be more intrusive and less reliable than the one without the sensors, which is described in this disseration. In addition, the small diameters of the catheters may also restrict the idea of mounting sensors on the distal tip. The other approach to obtain the force information is to infer it from the information outside the body. This will demand an accurate mathematical model that describes the force and motion relation called kinetic model, and unfortunately, such a kinetic model is not available in the literature.
In this dissertation, a kinetic model for steerable catheters is presented wich captures the following characteristics of the steerable
catheter, namely (1) the geometrical non-linear behavior of the
catheter in motion, (2) the deformable pathway, (3) the friction between the
catheter and the pathyway, and (4) the contact between the
catheter and pathway. A non-linear finite element system (SPACAR) was employed to capture these characteristics. A test-bed was built and an experiment was carried out to verify the developed kinetic model.
The following conclusions can be drawn from this dissertation: (1) the developed kinetic model is accurte in comparison with those in literature; (2) the Dahl friction model, the LuGre friction model and the simplified LuGre friction model are able to capture the friction behavior between the
catheter and the pathway but the Coulomb friction model fails (as it cannot capture the hysteresis property which has a significant influence on the behavior of the
catheter); (3) the developed kinetic model has the potential of being used to optimize the design and operation of steerable catheters with several salient findings that (3a) the maximal contact force between the
catheter and the pathway occurs on the tip of the distal part or the connecting part between the distal part and
catheter body of the
catheter and (3b) the rigidity and length of the distal part are crucial structural parameters that affect the motion and force transmission significantly.
There are several contributions made by this dissertation. In the field of the steerable
catheter, biomechanics and bio-instrumentation, the contributions are summarized in the following: (1) the approach to develop the kinetic model of the steerable
catheter in a complex work environment is useful to model other similar compliant medical devices, such as endoscope; (2) the kinetic model of the steerable
catheter can provide the force information to improve the efficiency and safety of MIS (minimally invastive surgery) and to realize the “doctor-assisted”
catheter-based…
Advisors/Committee Members: Zhang, Chris, Luo, Yigang, Chen, Daniel, Boulfiza, Mohamed, Wu, Fangxiang, Gupta, Madan.
Subjects/Keywords: Steerable Catheter; Modeling; Kinetics; Contact; Continuum Manipulator
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hu, A. 1. (2016). DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7403
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Hu, Andy 1985-. “DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY.” 2016. Thesis, University of Saskatchewan. Accessed April 19, 2021.
http://hdl.handle.net/10388/7403.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Hu, Andy 1985-. “DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY.” 2016. Web. 19 Apr 2021.
Vancouver:
Hu A1. DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY. [Internet] [Thesis]. University of Saskatchewan; 2016. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/10388/7403.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Hu A1. DEVELOPMENT OF A KINETIC MODEL FOR STEERABLE CATHETERS FOR MINIMALLY INVASIVE SURGERY. [Thesis]. University of Saskatchewan; 2016. Available from: http://hdl.handle.net/10388/7403
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan
19.
Friedt, Jill.
Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU.
Degree: 2011, University of Saskatchewan
URL: http://hdl.handle.net/10388/ETD-2011-07-19
► For improved client outcomes, nurses must be able to synthesize information from research and implement this information in the care of complex clients’ needs. The…
(more)
▼ For improved client outcomes, nurses must be able to synthesize information from research and implement this information in the care of complex clients’ needs. The purpose of this study was to assess registered nurses’ knowledge of the evidence based guidelines for preventing central line infections in the context of Intensive Care Units, before and after implementation of a checklist and an educational program, using quasi-experimental pre-test and post-test interrupted time series design. The questionnaire “Knowledge of Evidence-Based Guideline for Preventing Central Venous
Catheter-Related Infection” developed by Labeau, Vereecke, Vandijck, Claes, and Blot (2008) was used to assess the nurses’ knowledge with respect to central venous
catheter maintenance factors as outlined in the Centers for Disease Control (CDC, 2002) guidelines. Following ethics approval, a convenience sample of registered nurses was given a self report questionnaire. Guideline knowledge was examined by age, education level, number of years in practice, and gender to explore potential differences within and between groups; no statistically significant differences were found between the groups. After the intervention, there was a statistically significant increase in mean knowledge score for the intervention group, but not for the comparison group. In addition, the mean post-test score was significantly higher for the intervention group compared to the comparison group. In the 12 months following the intervention, no primary bloodstream infections were reported at the intervention site. The results indicate that implementation of a checklist with educational reinforcement can increase nurses’ knowledge and may contribute to decreasing central venous
catheter blood stream infection rates. An understanding of the nurses’ current knowledge level allows adaptation of beneficial strategies to increase research utilization and synthesize information toward better client outcomes in the context of the intensive care specialty. Decreasing infection rates saves lives, improves quality of care, and leads to better patient outcomes.
Advisors/Committee Members: Semchuk, Karen M., Goodridge, Donna, Donnelly, Glenn.
Subjects/Keywords: central venous catheter; infection; ICU; nurses' knowledge
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Friedt, J. (2011). Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2011-07-19
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Friedt, Jill. “Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU.” 2011. Thesis, University of Saskatchewan. Accessed April 19, 2021.
http://hdl.handle.net/10388/ETD-2011-07-19.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Friedt, Jill. “Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU.” 2011. Web. 19 Apr 2021.
Vancouver:
Friedt J. Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU. [Internet] [Thesis]. University of Saskatchewan; 2011. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/10388/ETD-2011-07-19.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Friedt J. Central Venous Catheter Related Infections: The Impact of an Educational Program on Nurses’ Knowledge and Infection Rates in an ICU. [Thesis]. University of Saskatchewan; 2011. Available from: http://hdl.handle.net/10388/ETD-2011-07-19
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queensland University of Technology
20.
Noonan, Katherine.
Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination.
Degree: 2011, Queensland University of Technology
URL: https://eprints.qut.edu.au/49852/
► Background: Catheter ablation for atrial fibrillation (AF) is more efficacious than antiarrhythmic therapy. Post ablation recurrences reduce ablation effectiveness and are contributed by lesion discontinuity…
(more)
▼ Background: Catheter ablation for atrial fibrillation (AF) is more efficacious than antiarrhythmic therapy. Post ablation recurrences reduce ablation effectiveness and are contributed by lesion discontinuity in the fibrotic linear ablation lesions.
The anti-fibrotic role of statins in reducing AF is being assessed in current trials. By reducing the chronic pathological fibrosis that occurs in AF they may reduce AF. However if statins also have an effect on the acute therapeutic fibrosis of an ablation, this could exacerbate lesion discontinuity and AF recurrence. We tested the hypothesis that statins attenuate ablation lesion continuity in a recognised pig atrial linear ablation model.
Aims: To assess whether Atorvastatin diminishes the bi-directional conduction block produced by a linear atrial ablation lesion.
Methods: Sixteen pigs were randomised to statin (n=8) or placebo (n=8) with drug pre-treatment for 3 days and a further 4 weeks. At initial electrophysiological study (EPS1) 3D right atrium (RA) mapping and a vertical ablation linear lesion in the posterior RA with bidirectional conduction block were completed (Gepstein Circ 1999). Follow-up electrophysiological assessment (EPS2) at 28 days assessed bidirectional conduction block maintenance.
Results: Data of 15/16 (statin=7) pigs were analysed. Mean lesion length was 3.7 ± 0.8cm with a mean of 17.9 ± 5.7 lesion applications. Bi-directional conduction block was confirmed in 15/15 pigs (100%) at EPS1 and EPS2.
Conclusions: Atorvastatin did not affect ablation lesion continuity in this pig atrial linear ablation model. If patients are on long-term statins for AF reduction, periablation cessation is probably not necessary.
Subjects/Keywords: atrial fibrillation; catheter ablation; inflammation; statin
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Noonan, K. (2011). Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination. (Thesis). Queensland University of Technology. Retrieved from https://eprints.qut.edu.au/49852/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Noonan, Katherine. “Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination.” 2011. Thesis, Queensland University of Technology. Accessed April 19, 2021.
https://eprints.qut.edu.au/49852/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Noonan, Katherine. “Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination.” 2011. Web. 19 Apr 2021.
Vancouver:
Noonan K. Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination. [Internet] [Thesis]. Queensland University of Technology; 2011. [cited 2021 Apr 19].
Available from: https://eprints.qut.edu.au/49852/.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Noonan K. Do anti-inflammatory agents promote linear ablation lesion discontinuities? : an electrophysiological examination. [Thesis]. Queensland University of Technology; 2011. Available from: https://eprints.qut.edu.au/49852/
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Guelph
21.
Ogilvie, Adam Timothy.
THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI.
Degree: Doctor of Veterinary Science, Department of Clinical Studies, 2015, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8669
► Catheter-associated bacteriuria (CAB) and urinary tract infection (CAUTI) are important clinical problems in catheterized humans and dogs. A variety of methods to reduce CAB and…
(more)
▼ Catheter-associated bacteriuria (CAB) and urinary tract infection (CAUTI) are important clinical problems in catheterized humans and dogs. A variety of methods to reduce CAB and CAUTI have been investigated, and in humans, silver coating of urinary catheters has been shown to reduce CAB and CAUTI in randomized prospective clinical trials. The objectives of the studies reported in this thesis are to evaluate adherence of clinical isolates of E. coli to a silver coated urinary
catheter, evaluate the potential association of E. coli urovirulence factors to E. coli biofilm formation in vitro, and assess the efficacy of the silver coated urinary
catheter in canine patients in a randomized clinical trial. Clinical isolates of E. coli were incubated with silver coated and standard (uncoated) urinary catheters. Significantly fewer bacteria were adhered to the silver coated urinary
catheter at 24, 48, and 72 hours of incubation, and following subjective analysis using SEM analysis. Clinical isolates of E. coli were investigated for the presence of urovirulence factors and the association between these urovirulence factors and biofilm formation in vitro. Prevalence of urovirulence factors were similar to what has been reported, and cnf1 was associated with biofilm formation. A prospective, randomized, controlled clinical trial was performed to assess the ability of silver coated urinary catheters to reduce CAB and CAUTI in hospitalized dogs requiring catheterization. Catheterized dogs were assessed for bacteriuria, positive culture, and urinary tract infections following catheterization. No significant differences were noted between groups in regard to CAB, CAUTI, and positive culture incidence in the two groups. We have shown that clinical E. coli isolates adhered less to a silver coated urinary
catheter compared to a non-silver coated urinary
catheter in vitro, and that cnf1 is associated with in vitro biofilm formation. We were unable to detect a significant difference in CAUTI or CAB in hospitalized dogs, most likely due to low study numbers. Further clinical studies are required to determine the utility of these catheters in hospitalized patients.
Advisors/Committee Members: Brisson, Brigitte (advisor).
Subjects/Keywords: Silver; Urine; Urinary Catheter; Biofilm; Escherichia coli
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ogilvie, A. T. (2015). THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8669
Chicago Manual of Style (16th Edition):
Ogilvie, Adam Timothy. “THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI.” 2015. Doctoral Dissertation, University of Guelph. Accessed April 19, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8669.
MLA Handbook (7th Edition):
Ogilvie, Adam Timothy. “THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI.” 2015. Web. 19 Apr 2021.
Vancouver:
Ogilvie AT. THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI. [Internet] [Doctoral dissertation]. University of Guelph; 2015. [cited 2021 Apr 19].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8669.
Council of Science Editors:
Ogilvie AT. THE IMPACT OF SILVER-COATING OF A URINARY CATHETER ON BACTERIAL ADHERENCE, BIOFILM FORMATION, BACTERIURIA, POSITIVE CULTURE, UTI, AND THE ASSOCIATION OF UROVIRULENCE FACTORS WITH BIOFILM FORMATION IN ESCHERICHIA COLI. [Doctoral Dissertation]. University of Guelph; 2015. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8669

Queen Mary, University of London
22.
Ullah, Waqas.
Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation.
Degree: PhD, 2015, Queen Mary, University of London
URL: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9020
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667453
► The interaction between the mapping/ablation catheter and left atrial (LA) myocardium potentially affects the LA electrical and mechanical properties and impacts on ablation efficacy. Using…
(more)
▼ The interaction between the mapping/ablation catheter and left atrial (LA) myocardium potentially affects the LA electrical and mechanical properties and impacts on ablation efficacy. Using catheters able to provide real-time contact force (CF) measurement, it has become possible to explore these relationships in vivo. In 60 persistent atrial fibrillation (AF) patients, ablation CF was higher in the right than left wide area circumferential (WACA) lines and where steerable transseptal sheaths were used. Differences were also apparent in the burden of WACA segment reconnection but did not just reflect differences in ablation CFs, suggesting factors other than CF contribute to ablation efficacy. Relationships between ablation force time integral (FTI), impedance drop and electrogram attenuation were assessed in 15 persistent AF patients. FTI significantly correlated with electrogram attenuation and impedance drop from ablation. The relationship was stronger for the former but in both cases plateaued at 500g.s, suggesting no ablation efficacy gains beyond this. Factors further affecting CF and ablation efficacy, the latter judged by impedance drop, were assessed in 30 patients. The variability of the CF waveform and catheter locational stability were both affected by factors including atrial rhythm and catheter delivery mode. Greater CF variability, catheter drift and perpendicular catheter contact were associated with reduced ablation efficacy. The relationship between CF and the electrogram was assessed in 30 patients. The size of the electrogram complexes was affected by CF increases but only where initial CF was <10g. This was also the case for electrogram fractionation measurements. Increasing CF was associated with an increasing incidence of atrial ~ 3 ~ ectopics during sinus rhythm. Spectral parameters (dominant frequency and organisation index) were unaffected by CF. Various factors affect the contact between the catheter and LA myocardium. In turn, catheter contact significantly affects the electrogram during LA mapping and the efficacy of clinical radiofrequency ablation.
Subjects/Keywords: 617.4; Medicine; Catheter; Ablation; Left atrial myocardium
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APA ·
Chicago ·
MLA ·
Vancouver ·
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APA (6th Edition):
Ullah, W. (2015). Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation. (Doctoral Dissertation). Queen Mary, University of London. Retrieved from http://qmro.qmul.ac.uk/xmlui/handle/123456789/9020 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667453
Chicago Manual of Style (16th Edition):
Ullah, Waqas. “Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation.” 2015. Doctoral Dissertation, Queen Mary, University of London. Accessed April 19, 2021.
http://qmro.qmul.ac.uk/xmlui/handle/123456789/9020 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667453.
MLA Handbook (7th Edition):
Ullah, Waqas. “Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation.” 2015. Web. 19 Apr 2021.
Vancouver:
Ullah W. Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation. [Internet] [Doctoral dissertation]. Queen Mary, University of London; 2015. [cited 2021 Apr 19].
Available from: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9020 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667453.
Council of Science Editors:
Ullah W. Factors affecting catheter contact in the human left atrium, its impact on the electrogram and radiofrequency ablation. [Doctoral Dissertation]. Queen Mary, University of London; 2015. Available from: http://qmro.qmul.ac.uk/xmlui/handle/123456789/9020 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667453

University College Cork
23.
O'Donoghue, Kilian.
Electromagnetic tracking and steering for catheter navigation.
Degree: 2014, University College Cork
URL: http://hdl.handle.net/10468/2025
► This thesis explores the use of electromagnetics for both steering and tracking of medical instruments in minimally invasive surgeries. The end application is virtual navigation…
(more)
▼ This thesis explores the use of electromagnetics for both steering and tracking of medical instruments in minimally invasive surgeries. The end application is virtual navigation of the lung for biopsy of early stage cancer nodules. Navigation to the peripheral regions of the lung is difficult due to physical dimensions of the bronchi and current methods have low successes rates for accurate diagnosis. Firstly, the potential use of DC magnetic fields for the actuation of
catheter devices with permanently magnetised distal attachments is investigated.
Catheter models formed from various materials and magnetic tip formations are used to examine the usefulness of relatively low power and compact electromagnets. The force and torque that can be exerted on a small permanent magnet is shown to be extremely limited. Hence, after this initial investigation we turn our attention to electromagnetic tracking, in the development of a novel, low-cost implementation of a GPS-like system for navigating within a patient. A planar magnetic transmitter, formed on a printed circuit board for a low-profile and low cost manufacture, is used to generate a low frequency magnetic field distribution which is detected by a small induction coil sensor. The field transmitter is controlled by a novel closed-loop system that ensures a highly stable magnetic field with reduced interference from one transmitter coil to another. Efficient demodulation schemes are presented which utilise synchronous detection of each magnetic field component experienced by the sensor. The overall tracking accuracy of the system is shown to be less than 2 mm with an orientation error less than 1°. A novel demodulation implementation using a unique undersampling approach allows the use of reduced sample rates to sample the signals of interest without loss of tracking accuracy. This is advantageous for embedded microcontroller implementations of EM tracking systems. The EM tracking system is demonstrated in the pre-clinical environment of a breathing lung phantom. The airways of the phantom are successfully navigated using the system in combination with a 3D computer model rendered from CT data. Registration is achieved using both a landmark rigid registration method and a hybrid fiducial-free approach. The design of a planar magnetic shield structure for blocking the effects of metallic distortion from below the transmitter is presented which successfully blocks the impact of large ferromagnetic objects such as operating tables. A variety of shielding material are analysed with MuMetal and ferrite both providing excellent shieling performance and an increased signal to noise ratio. Finally, the effect of conductive materials and human tissue on magnetic field measurements is presented. Error due to induced eddy currents and capacitive coupling is shown to severely affect EM tracking accuracy at higher frequencies.
Advisors/Committee Members: Cantillon-Murphy, Padraig, IRCSET.
Subjects/Keywords: Electromagnetic tracking; Catheter navigation; Magnetic steering
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
O'Donoghue, K. (2014). Electromagnetic tracking and steering for catheter navigation. (Thesis). University College Cork. Retrieved from http://hdl.handle.net/10468/2025
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
O'Donoghue, Kilian. “Electromagnetic tracking and steering for catheter navigation.” 2014. Thesis, University College Cork. Accessed April 19, 2021.
http://hdl.handle.net/10468/2025.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
O'Donoghue, Kilian. “Electromagnetic tracking and steering for catheter navigation.” 2014. Web. 19 Apr 2021.
Vancouver:
O'Donoghue K. Electromagnetic tracking and steering for catheter navigation. [Internet] [Thesis]. University College Cork; 2014. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/10468/2025.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
O'Donoghue K. Electromagnetic tracking and steering for catheter navigation. [Thesis]. University College Cork; 2014. Available from: http://hdl.handle.net/10468/2025
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Florida Atlantic University
24.
Ganesan, Prasanth.
DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES.
Degree: 2019, Florida Atlantic University
URL: http://fau.digital.flvc.org/islandora/object/fau:41930
► Atrial Fibrillation (AF) is a debilitating heart rhythm disorder affecting over 2.7 million people in the US and over 30 million people worldwide annually. It…
(more)
▼ Atrial Fibrillation (AF) is a debilitating heart rhythm disorder affecting over 2.7 million people in the US and over 30 million people worldwide annually. It has a high correlation with causing a stroke and several other risk factors, resulting in increased mortality and morbidity rate. Currently, the non-pharmocological therapy followed to control AF is catheter ablation, in which the tissue surrounding the pulmonary veins (PVs) is cauterized (called the PV isolation - PVI procedure) aims to block the ectopic triggers originating from the PVs from entering the atrium. However, the success rate of PVI with or without other anatomy-based lesions is only 50%-60%.
A major reason for the suboptimal success rate is the failure to eliminate patientspecific non-PV sources present in the left atrium (LA), namely reentry source (a.k.a. rotor source) and focal source (a.k.a. point source). It has been shown from several animal and human studies that locating and ablating these sources significantly improves the long-term success rate of the ablation procedure. However, current technologies to locate these sources posses limitations with resolution, additional/special hardware requirements, etc. In this dissertation, the goal is to develop an efficient algorithm to locate AF reentry and focal sources using electrograms recorded from a conventionally used high-resolution multi-pole diagnostic catheter.
2019
Degree granted: Dissertation (Ph.D.) – Florida Atlantic University, 2019.
Collection: FAU
Advisors/Committee Members: Ghoraani, Behnaz (Thesis advisor), Florida Atlantic University (Degree grantor), College of Engineering and Computer Science, Department of Computer and Electrical Engineering and Computer Science.
Subjects/Keywords: Atrial Fibrillation – diagnosis; Algorithm; Catheter ablation
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Ganesan, P. (2019). DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES. (Thesis). Florida Atlantic University. Retrieved from http://fau.digital.flvc.org/islandora/object/fau:41930
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ganesan, Prasanth. “DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES.” 2019. Thesis, Florida Atlantic University. Accessed April 19, 2021.
http://fau.digital.flvc.org/islandora/object/fau:41930.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ganesan, Prasanth. “DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES.” 2019. Web. 19 Apr 2021.
Vancouver:
Ganesan P. DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES. [Internet] [Thesis]. Florida Atlantic University; 2019. [cited 2021 Apr 19].
Available from: http://fau.digital.flvc.org/islandora/object/fau:41930.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ganesan P. DEVELOPMENT OF AN ALGORITHM TO GUIDE A MULTI-POLE DIAGNOSTIC CATHETER FOR IDENTIFYING THE LOCATION OF ATRIAL FIBRILLATION SOURCES. [Thesis]. Florida Atlantic University; 2019. Available from: http://fau.digital.flvc.org/islandora/object/fau:41930
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology
25.
Sakes, A. (author).
Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses.
Degree: 2013, Delft University of Technology
URL: http://resolver.tudelft.nl/uuid:9052203c-1caa-4f30-b8cd-af2d75e6d60a
► Thesis on the design of a flexible morcellator for the surgical treatment of Cushing's disease in horses. Currently there is no surgical treatment possible in…
(more)
▼ Thesis on the design of a flexible morcellator for the surgical treatment of Cushing's disease in horses. Currently there is no surgical treatment possible in horses due to lack of a surgical approach and tools. In this study a new innovative flexible tool is developped in combination with a surgical approach that can be used for the surgical treatment. The prototype was succesfully tested, allowing for surgical treatment of Cushing's disease in horses in the near future.
BME
BioMechanical Engineering
Mechanical, Maritime and Materials Engineering
Advisors/Committee Members: Breedveld, P. (mentor), Arkenbout, E. (mentor).
Subjects/Keywords: morcellation; cushing's diseas; horse; endovascular; catheter; design
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MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Sakes, A. (. (2013). Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:9052203c-1caa-4f30-b8cd-af2d75e6d60a
Chicago Manual of Style (16th Edition):
Sakes, A (author). “Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses.” 2013. Masters Thesis, Delft University of Technology. Accessed April 19, 2021.
http://resolver.tudelft.nl/uuid:9052203c-1caa-4f30-b8cd-af2d75e6d60a.
MLA Handbook (7th Edition):
Sakes, A (author). “Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses.” 2013. Web. 19 Apr 2021.
Vancouver:
Sakes A(. Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses. [Internet] [Masters thesis]. Delft University of Technology; 2013. [cited 2021 Apr 19].
Available from: http://resolver.tudelft.nl/uuid:9052203c-1caa-4f30-b8cd-af2d75e6d60a.
Council of Science Editors:
Sakes A(. Design of the flexible HORSE morcellator for the surgical treatment of Cushing's disease in horses. [Masters Thesis]. Delft University of Technology; 2013. Available from: http://resolver.tudelft.nl/uuid:9052203c-1caa-4f30-b8cd-af2d75e6d60a

University of Minnesota
26.
Chelikani, Srikar.
Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications.
Degree: PhD, Mechanical Engineering, 2014, University of Minnesota
URL: http://hdl.handle.net/11299/162634
► Numerical simulation models can be a highly effective starting point for the optimal design of biomedical devices. This concept forms the underpinnings of the research…
(more)
▼ Numerical simulation models can be a highly effective starting point for the optimal design of biomedical devices. This concept forms the underpinnings of the research to be reported in this thesis. Three unique medical device applications are considered, and numerical modeling and simulation is performed to enable a near approach to an optimal design. Furthermore, numerical models can also provide valuable guidelines for experimentation and product development. Each of the considered applications serves a therapeutic function. The common denominator to all of the applications is the major role played by fluid dynamics. For each of these applications, a model that conforms closely to the physical situation is formulated and subsequently implemented by numerical computation to yield outcomes of practical utility. The first of the applications was motivated by the reality that certain patients require frequent access to the vascular system. For example, drug infusion during chemotherapy and dialysis treatment requires such access. To facilitate these intrusions, infusion ports are implanted at suitable sites. The design of such ports must enable convenience in injecting and extracting fluid media. Furthermore, if blood is one of the media, the geometry of the port must be tailored to avoid hemolysis. Filtration is a major issue in the sanitary handling of biological fluids. The manufacture of such filtration media and other biomedical sterile fabrics makes use of very fine diameter fibers. The second major focus of this thesis is to provide a highly effective means for the production of the needed fibers. The manufacturing process which was majorly improved by the present innovations is the melt-blowing process.There are many situations in which biomedical fluids must be extracted from the human body. For example, spent tracer fluids used in angiographies become a possible source of kidney damage unless they are extracted. The final focus of the thesis research was to develop a highly effective numerical model whose application guides the design of suction catheters suitable to the existing biological conditions.
Subjects/Keywords: Coanda-effect; Infusion Port; Suction Catheter
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chelikani, S. (2014). Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/162634
Chicago Manual of Style (16th Edition):
Chelikani, Srikar. “Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications.” 2014. Doctoral Dissertation, University of Minnesota. Accessed April 19, 2021.
http://hdl.handle.net/11299/162634.
MLA Handbook (7th Edition):
Chelikani, Srikar. “Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications.” 2014. Web. 19 Apr 2021.
Vancouver:
Chelikani S. Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications. [Internet] [Doctoral dissertation]. University of Minnesota; 2014. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/11299/162634.
Council of Science Editors:
Chelikani S. Numerical simulation for the management of steady and unsteady flows in the presence of mixing for biomedical applications. [Doctoral Dissertation]. University of Minnesota; 2014. Available from: http://hdl.handle.net/11299/162634

University of Minnesota
27.
Hein, Matthew.
Electrochemical Deposition of Magnetics Based Sensors.
Degree: PhD, Electrical Engineering, 2019, University of Minnesota
URL: http://hdl.handle.net/11299/211758
► Within the context of this thesis, advancements in sensor technology are driven in three separate applications. In each application electrochemistry is used as one of…
(more)
▼ Within the context of this thesis, advancements in sensor technology are driven in three separate applications. In each application electrochemistry is used as one of the primary fabrication steps, and magnetic phenomena are sensed in order to convey information about the different systems. The medical device industry is an area where various sensors are seeing increased use. Electromagnetic catheter tracking is an application that depends on high-quality magnetic sensors. The size of the sensor is a significant design constraint in catheters. Investigation of a microfabricated inductive sensor is pursued in chapter 4 of this thesis. High shape anisotropy inductive structures utilizing etched aluminum oxide as electroplating templates are investigated through first-order modeling and fabrication process development. Results show that the AAO is capable of producing high aspect ratio inductive structures though further development would be needed to achieve the consistency in etching required for large scale device fabrication. Biomimetic devices are another area of scientific interest where magnetics can play a role. Electroplated magnetic nanowires can act like large arrays of cilia. In chapter 5, biomimetic nanowire arrays are fabricated into microfluidic channels, and their movement sensed via a magnetic sensor. The nanowires provide a magnetic field that bends as fluid flows through the channel which enables a simple flow measurement through microfluidic channels. Similarly, a low frequency (>10Hz) vibration sensor is demonstrated utilizing a nanowire array above a magnetic sensor. Vibration of the sensor imparts momentum on the nanowires, which bend and leads to a time-varying field. In chapter 6, electrodeposition of Galfenol on a cylindrical surface is demonstrated for the first time. Galfenol has a large magnetostriction constant up to ~400 ppm. Utilizing a rotating cylinder electrode, the parameters to deposit Fe1-xGax films in the x = 15 to 35 range were found. The film's magnetostriction was then demonstrated as part of a torque sensor where magnetic anisotropy was controlled through texturing of the cylinder surface. The effect of magnetic shape anisotropy can be seen to play a significant role in the sensor's output by increasing the sensitivity of the sensor nearly 6x that of the non-textured film.
Subjects/Keywords: Catheter; Electromagnetic tracking; Galfenol; Magnetics; Navigation; Sensors
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hein, M. (2019). Electrochemical Deposition of Magnetics Based Sensors. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/211758
Chicago Manual of Style (16th Edition):
Hein, Matthew. “Electrochemical Deposition of Magnetics Based Sensors.” 2019. Doctoral Dissertation, University of Minnesota. Accessed April 19, 2021.
http://hdl.handle.net/11299/211758.
MLA Handbook (7th Edition):
Hein, Matthew. “Electrochemical Deposition of Magnetics Based Sensors.” 2019. Web. 19 Apr 2021.
Vancouver:
Hein M. Electrochemical Deposition of Magnetics Based Sensors. [Internet] [Doctoral dissertation]. University of Minnesota; 2019. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/11299/211758.
Council of Science Editors:
Hein M. Electrochemical Deposition of Magnetics Based Sensors. [Doctoral Dissertation]. University of Minnesota; 2019. Available from: http://hdl.handle.net/11299/211758

University of Minnesota
28.
Schmidt, Megan.
Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias.
Degree: PhD, Biomedical Engineering, 2018, University of Minnesota
URL: http://hdl.handle.net/11299/198366
► The object of this thesis was to investigate applications for monophasic action potential (MAP) recordings in the diagnosis and treatment of cardiac arrhythmias. To meet…
(more)
▼ The object of this thesis was to investigate applications for monophasic action potential (MAP) recordings in the diagnosis and treatment of cardiac arrhythmias. To meet this objective, MAPs were measured in situ and in vitro, during sinus rhythm and cardiac arrhythmias. MAPs were analyzed for potential clinical applications and in novel cardiac mapping and ablation catheter concepts. MAPs are focal action potential recordings which are directly proportional to the electrical activities of cells adjacent to a contacting electrode. When sufficient force is applied between a contacting electrode and the myocardium, the cells directly beneath become mechanically depolarized; i.e. electrically inactive. As a transmembrane action potential passes through this region, a change in boundary currents between the active and inactive cells, via gap junctions, results in a waveform that is proportional to the original action potential. The Visible Heart® Apparatus provides us with the ability to study large mammalian hearts, including human, in an in vitro setting; allowing the testing of prototype catheter concepts prior to in situ or in vivo work. To validate MAPs from an in vitro working heart model a comparison study was conducted. Over the course of 2 hours in situ and 2 hours in vitro MAPs were recorded from the right atrium, left atrium, and right ventricle (endocardially and epicardially). Overall, there were no significant differences between recorded signals when compared to in situ baseline recordings. Based on these findings, systems like the Visible Heart® Apparatus can be used as a platform on which cardiac action potentials can be studied. The clinical application of MAP recordings, as they pertain to radiofrequency (RF) ablations, was also evaluated. To ensure proper lesion formation, RF ablation requires a catheter contact force (CF) of between 10-20 grams to be maintained throughout energy delivery. It was determined that MAP waveforms could only be recorded when at least 10-15 grams of CF was applied to the myocardium. In other words, the presence of MAP waveforms would indicate that sufficient CF has been applied prior to the delivery of RF energy. Additionally, MAP waveforms were found to correlate with RF lesion size. MAP amplitudes at baseline (pre-ablation) were significantly larger than amplitudes from lesions which matured to greater than 1 mm deep. MAPs were also able to distinguish between lesions between 1-2mm deep, and those deeper than 2mm. Moving forward, MAPs may be used in evaluating cardiac viability, both through recording from induced lesions, as well as in regions of scarred or ischemic myocardium.
Subjects/Keywords: ablation; cardiac; catheter; electrophysiology; monophasic action potential
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schmidt, M. (2018). Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias. (Doctoral Dissertation). University of Minnesota. Retrieved from http://hdl.handle.net/11299/198366
Chicago Manual of Style (16th Edition):
Schmidt, Megan. “Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias.” 2018. Doctoral Dissertation, University of Minnesota. Accessed April 19, 2021.
http://hdl.handle.net/11299/198366.
MLA Handbook (7th Edition):
Schmidt, Megan. “Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias.” 2018. Web. 19 Apr 2021.
Vancouver:
Schmidt M. Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias. [Internet] [Doctoral dissertation]. University of Minnesota; 2018. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/11299/198366.
Council of Science Editors:
Schmidt M. Utility of Monophasic Action Potentials in the Diagnosis and Treatment of Cardiac Arrhythmias. [Doctoral Dissertation]. University of Minnesota; 2018. Available from: http://hdl.handle.net/11299/198366

University of Melbourne
29.
Voskoboinik, Aleksandr.
A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies.
Degree: 2019, University of Melbourne
URL: http://hdl.handle.net/11343/225724
► Atrial fibrillation (AF) is a leading epidemic of cardiovascular disease in developed countries, owing to an ageing population and the Western lifestyle. In addition to…
(more)
▼ Atrial fibrillation (AF) is a leading epidemic of cardiovascular disease in developed countries, owing to an ageing population and the Western lifestyle. In addition to effects on quality of life and economic burden on the health system, AF is associated with heart failure, stroke and a higher risk of mortality. The focus of AF management over the last decade has shifted from anticoagulation and rate control to a more a more holistic and multi-faceted approach. This encompasses attention to potentially modifiable lifestyle factors and adoption of novel invasive strategies such as catheter ablation to maintain rhythm control.
The aim of this thesis is to explore these emerging strategies in AF management, with a focus on rhythm control. Initially, we assess the impact of lifestyle related factors on AF and cardiovascular disease. The emphasis initially is on the effects of habitual alcohol consumption on the atria and ventricles and the impact of abstinence in the AF population. We explore novel strategies for cardioversion of persistent AF, focussing on improving success rates in obese patients. Finally, we explore the evolution of catheter ablation as an increasingly utilized rhythm control strategy.
Chapter 1 details our evolving understanding of AF pathogenesis, and the impact of common lifestyle factors on arrhythmogenesis, with a focus on alcohol, caffeine, diet and obesity. We then explore the evidence base for rhythm control strategies, including role of anti-arrhythmics, cardioversion and catheter ablation.
Chapter 2 and 3 explore the impact of regular alcohol consumption on the atrium to determine whether there is an association with electrical and structural remodelling. Chapter 2 is a prospective observational study of 75 patients undergoing novel high-density electroanatomical mapping of their left atria at the time of AF ablation. We compare non-drinkers, mild drinkers and moderate drinkers to determine whether there are differences in voltage and conduction properties between the three groups. Chapter 3 is a prospective observational study of 160 AF patients comparing atrial size, mechanical and reservoir function based on degree of alcohol intake utilizing high-definition cardiac magnetic resonance imaging (CMR). We conclude that moderate-to-heavy levels of consumption are associated with adverse atrial remodelling, characterised by reduction in voltage, slowing of atrial conduction, atrial dilatation and impaired mechanical function suggestive of progressive fibrosis.
Chapter 4 is a randomized controlled trial of 140 moderate habitual drinkers with a history of AF. We examine the impact of 6 months of abstinence on risk of AF recurrence, AF burden, symptom scores, blood pressure, weight and atrial structure / function. Key findings include reduction in AF recurrence rates, with small but significant reductions in systolic blood pressure and weight. This is the first randomized trial to demonstrate the benefits of abstinence from alcohol in the AF population.
Chapter 5 examines the…
Subjects/Keywords: atrial fibrillation; alcohol; catheter ablation; cardioversion
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Voskoboinik, A. (2019). A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies. (Doctoral Dissertation). University of Melbourne. Retrieved from http://hdl.handle.net/11343/225724
Chicago Manual of Style (16th Edition):
Voskoboinik, Aleksandr. “A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies.” 2019. Doctoral Dissertation, University of Melbourne. Accessed April 19, 2021.
http://hdl.handle.net/11343/225724.
MLA Handbook (7th Edition):
Voskoboinik, Aleksandr. “A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies.” 2019. Web. 19 Apr 2021.
Vancouver:
Voskoboinik A. A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies. [Internet] [Doctoral dissertation]. University of Melbourne; 2019. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/11343/225724.
Council of Science Editors:
Voskoboinik A. A multi-faceted approach to atrial fibrillation: from lifestyle factors to invasive therapies. [Doctoral Dissertation]. University of Melbourne; 2019. Available from: http://hdl.handle.net/11343/225724
30.
Kidde, Katherine.
The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses.
Degree: 2020, The Catholic University of America
URL: http://hdl.handle.net/1961/cuislandora:214701
► According to the American Society for Pain Management in Nursing, pharmacological and non- pharmacological pain management should be used during all painful procedures (Czarnecki et…
(more)
▼ According to the American Society for Pain Management in Nursing, pharmacological and non- pharmacological pain management should be used during all painful procedures (Czarnecki et al., 2011). At the Naval Medical Center Portsmouth, direct care nurses are not privileged to use transdermal lidocaine for intravenous (IV) placement, resulting in patients experiencing unnecessary pain. Vapocoolant spray has been shown to be an alternative to transdermal lidocaine for IV placement analgesia. The PICOT question for this project was, in a sample of direct care nurses and patients, does the use of vapocoolant spray decrease pain during IV placement in a one-month trial period. Secondarily, nurse and patient satisfaction with the vapocoolant spray, and their preference for its use was measured. During the trial period, after a patient received vapocoolant spray during their IV placement they were asked to complete a survey assessing their opinions on vapocoolant spray. At the end on the trial period, nurses were asked to complete a survey detailing their opinions of vapocoolant spray. Results of the project were mixed. All of the patients reported that their pain was either the same or better with vapocoolant spray. Half of the patients, 57.1%, would use the spray again. While 100% of the nurses indicated that the patients appeared to be in less pain, only 50% would use the spray in the future. Despite a small sample size, this project supports the continued use of vapocoolant spray during IV placement.
Nursing
intravenous catheter, IV placement analgesia, numbing spray, pain during intravenous catheter, vapocoolant spray
Nursing
Degree Awarded: D.N.P. Nursing. The Catholic University of America
Advisors/Committee Members: The Catholic University of America (Degree granting institution), Agazio, Janice (Thesis advisor), Carolan-Doerflinger, Deirdre (Committee member), Suszan, Lauren (Committee member).
Subjects/Keywords: intravenous catheter; IV placement analgesia; numbing spray; pain during intravenous catheter; vapocoolant spray
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APA (6th Edition):
Kidde, K. (2020). The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses. (Thesis). The Catholic University of America. Retrieved from http://hdl.handle.net/1961/cuislandora:214701
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kidde, Katherine. “The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses.” 2020. Thesis, The Catholic University of America. Accessed April 19, 2021.
http://hdl.handle.net/1961/cuislandora:214701.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kidde, Katherine. “The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses.” 2020. Web. 19 Apr 2021.
Vancouver:
Kidde K. The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses. [Internet] [Thesis]. The Catholic University of America; 2020. [cited 2021 Apr 19].
Available from: http://hdl.handle.net/1961/cuislandora:214701.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kidde K. The Use of Vapocoolant Spray for Intravenous Catheter Placement Analgesia by Direct Care Nurses. [Thesis]. The Catholic University of America; 2020. Available from: http://hdl.handle.net/1961/cuislandora:214701
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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