subject:(Canine distemper)

University of Pretoria

1. Woma, Timothy Yusufu. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .

Degree: 2009, University of Pretoria

URL: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

► Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains… (more)

▼ Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains for in vitro experiments. There are no reports of CDV isolations in southern Africa, and although CDV is said to have geographically distinct lineages, molecular information of African strains has not yet been documented. Clinical specimens consisting of whole blood, spleen, lungs, brain and cerebrospinal fluid from dogs with clinical signs suggestive of distemper were obtained from private veterinary practices and diagnostic laboratories in Gauteng province, South Africa. One hundred and sixty two specimens from 124 dogs were inoculated into Vero cells expressing canine signalling lymphocyte activation molecule (Vero.DogSLAM). Cytopathic effects (CPE) in the form of syncytia formation and cell necrosis were observed in 33 (20.4%) specimens within 24 hours of inoculation and the presence of CDV was confirmed with the aid of the direct fluorescent antibody test and electronmicroscopy (EM). Viruses isolated in cell cultures were subjected to reverse transcription – polymerase chain reaction (RT-PCR), and the complete H gene was sequenced and phylogenetically analysed with other strains from GenBank. The animals all displayed the catarrhal, systemic, or nervous signs of the disease. Four of the dogs positive for CDV by viral isolation had a history of prior vaccinations to canine distemper. Seventy three percent of all positive dogs were less than 12 months old. There was no breed or sex predisposition to CDV infection in domestic dogs. Phylogenetic comparisons of the complete H gene of CDV isolates from different parts of the world (available in GenBank) with wild-type South African isolates revealed nine clades. All South African isolates form a separate African clade of their own and thus are clearly separated from the American, European, Asian, Arctic and vaccine virus clades. It is likely that only the ‘African lineage’ of CDV may be circulating in South Africa currently, and the viruses isolated from dogs vaccinated against CDV are not the result of reversion to virulence of vaccine strains, but infection with wild-type strains. Copyright Advisors/Committee Members: Van Vuuren, Moritz (advisor).

Subjects/Keywords: Canine distemper virus; Domestic dogs; South Africa

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Woma, T. Y. (2009). The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . (Masters Thesis). University of Pretoria. Retrieved from http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

Chicago Manual of Style (16^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .” 2009. Masters Thesis, University of Pretoria. Accessed March 05, 2021. http://upetd.up.ac.za/thesis/available/etd-07142009-151317/.

MLA Handbook (7^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa .” 2009. Web. 05 Mar 2021.

Vancouver:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . [Internet] [Masters thesis]. University of Pretoria; 2009. [cited 2021 Mar 05]. Available from: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/.

Council of Science Editors:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa . [Masters Thesis]. University of Pretoria; 2009. Available from: http://upetd.up.ac.za/thesis/available/etd-07142009-151317/

2. Vania Gomes dos Santos. Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados.

Degree: 2008, Universidade Federal Rural do Rio de Janeiro

URL: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=900

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A maioria das enfermidades infecciosas e parasitárias em cães apresenta uma fase inicial com sintomas inespecíficos como apatia, anorexia e ocasionalmente febre evoluindo com alterações… (more)

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A maioria das enfermidades infecciosas e parasitárias em cães apresenta uma fase inicial com sintomas inespecíficos como apatia, anorexia e ocasionalmente febre evoluindo com alterações respiratórias, gastrointestinais e nervosas. Em geral essas alterações são relacionadas com a infecção por viroses como cinomose, bacterioses como Ehrlichia sp., além da potencial presença de agentes etiológicos exóticos como Borrelia sp. O presente estudo teve como objetivos detectar qualitativamente o antígeno do vírus da cinomose, avaliar a ocorrência de anticorpos anti-Ehrlichia sp. e anticorpos homólogos contra Borrelia burgdorferi em cães acautelados no Centro de Controle de Zoonoses (CCZ) Paulo Dacorso Filho, pertencente ao Município do Rio de Janeiro, Brasil e correlacionar com sintomas clínicos e alterações hematológicas. Para realização da pesquisa, foram coletadas amostras de sangue de 38 animais alojados coletivamente em cinco baias de uma população de 125 cães sem raça definida, machos e fêmeas, de diferentes idades e com histórico de vacinação desconhecido. A presença de um animal positivo para o vírus da cinomose e ausência de casos clínicos indica que os cães estavam naturalmente imunizados ou com infecção subclínica. O número de animais positivos, porém assintomáticos, para Anaplasma platys e Ehrlichia canis à análise morfológica em esfregaços sangüíneos foi elevado, especialmente para A. platys indicando uma alta prevalência de infecção sub-clínica. Em contrapartida houve um alto título de anticorpos anti-Ehrlichia sp. evidenciando exposição prévia a este agente. A elevada presença de anticorpos homólogos anti-Borrelia burgdorferi indica exposição prévia ou reação cruzada com espiroqueta do gênero Borrelia e indica a circulação do agente etiológico na região estudada.

Most infectious and parasitic diseases in dogs, have an initial phase with nonspecific symptoms such as apathy, anorexia and occasionally fever with respiratory, gastrointestinal and nervous abnormalities. Generally these changes are related to infection by canine distemper, Ehrlichia sp and the potential presence of exotic etiological agents such as Borrelia sp. This study aimed to detect the occurrence of the canine distemper virus, antibodies against Ehrlichia sp and homologous antibodies against Borrelia burgdorferi in dogs of the Zoonotic Diseases Control Center Paulo Dacorso Filho, of Rio de Janeiro, Brazil correlating with clinical symptoms and haematological disorders. To conduct the research, blood samples were collected from 38 animals collectively housed in five boxes from a population of 125 dogs without defined race, sex, different ages and with an unknown vaccination history. The presence of a positive animal for the canine distemper virus and the absence of clinical cases indicate that the dogs were naturally immunized or have subclinical infection. The number of positive but asymptomatic animals, for Anaplasma platys and Ehrlichia canis in the morphological analysis of blood smears was high, especially for A. platys indicating a high…

Advisors/Committee Members: Adivaldo Henrique da Fonseca, Rita de Cássia Alves Alcantara de Menezes.

Subjects/Keywords: Cinomose; ehrlichiose; borreliose; cães.; MEDICINA VETERINARIA; Canine distemper; ehrlichiosis; borreliosis; dogs.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Santos, V. G. d. (2008). Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados. (Thesis). Universidade Federal Rural do Rio de Janeiro. Retrieved from http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=900

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Santos, Vania Gomes dos. “Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados.” 2008. Thesis, Universidade Federal Rural do Rio de Janeiro. Accessed March 05, 2021. http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=900.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Santos, Vania Gomes dos. “Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados.” 2008. Web. 05 Mar 2021.

Vancouver:

Santos VGd. Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados. [Internet] [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2008. [cited 2021 Mar 05]. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=900.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Santos VGd. Aspectos Clínicos e Laboratoriais da Cinomose, Ehrlichiose e Borreliose em Cães (Canis familiaris, Linnaeus, 1758) Naturalmente Infectados. [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2008. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=900

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University

3. Higgins, Robert James. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.

Degree: PhD, Graduate School, 1980, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

Subjects/Keywords: Biology; Encephalomyelitis; Canine distemper virus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Higgins, R. J. (1980). Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

Chicago Manual of Style (16^th Edition):

Higgins, Robert James. “Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.” 1980. Doctoral Dissertation, The Ohio State University. Accessed March 05, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532.

MLA Handbook (7^th Edition):

Higgins, Robert James. “Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus.” 1980. Web. 05 Mar 2021.

Vancouver:

Higgins RJ. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. [Internet] [Doctoral dissertation]. The Ohio State University; 1980. [cited 2021 Mar 05]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532.

Council of Science Editors:

Higgins RJ. Studies of the pathogenesis of encephalomyelitis in gnotobiotic dogs induced by canine distemper virus. [Doctoral Dissertation]. The Ohio State University; 1980. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487152450442532

Universidade do Rio Grande do Sul

4. Budaszewski, Renata da Fontoura. Análise filogenética do vírus da cinomose canina no Brasil.

Degree: 2013, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/69909

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O vírus da cinomose canina (CDV) é classificado no gênero Morbillivirus da família Paramyxoviridae e é o agente etiológico de uma das mais importantes doenças… (more)

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O vírus da cinomose canina (CDV) é classificado no gênero Morbillivirus da família Paramyxoviridae e é o agente etiológico de uma das mais importantes doenças virais de canídeos domésticos. A cinomose ocorre em todo o mundo e produz alta mortalidade em populações imunologicamente naïve. Apesar de encontrar-se bem controlada pela vacinação, casos de cinomose ocorrem esporadicamente tanto em cães vacinados quanto em não vacinados. Uma das causas suspeitas desta falha vacinal é a grande variabilidade genética entre cepas de CDV. O objetivo deste trabalho foi detectar e analisar a variabilidade genética do CDV circulante no País. Foram coletados 386 suabes retais de cães em diversas regiões do Brasil, dos quais se detectaram 155 positivos através de uma RT-nested-PCR de um fragmento do gene do nucleocapsídeo. Destes, 23 foram selecionados para amplificação parcial do gene da hemaglutinina, sequenciamento e análise filogenética. A grande maioria das sequências obtidas agrupou no genótipo América do Sul-I, que inclui isolados da Argentina e do Uruguai, com exceção de uma amostra similar à cepa vacinal Rockborn. A análise filogenética sugere a presença de pelo menos sete subgenótipos do genótipo América do Sul-I circulando neste continente. O grupo América do Sul-II é formado somente por isolados da Argentina. Além disso, propõe-se que este grupo e os clados Rockborn-like e Europa Selvagem sejam denominados subgenótipos dentro de um genótipo único.

Canine distemper virus (CDV) is classified in the genus Morbillivirus within the family Paramyxoviridae and is the etiologic agent of one of the most important viral diseases of domestic Canidea. It occurs worldwide and produces high mortality in immunologically naïve populations. Despite being well controlled by vaccination, cases of canine distemper occur sporadically in vaccinated and unvaccinated dogs. One of the suspected causes of this vaccine failure is the great genetic variability between strains of CDV. The objective of this study was to detect and analyze the genetic variability of CDV circulating in our country. Rectal swabs were collected from 386 dogs in various regions of Brazil, of which 155 were found positive by a nested RT-PCR of a fragment of the nucleocapsid gene. Of these, 23 were selected for partial amplification of the hemagglutinin gene, sequencing and phylogenetic analysis. The vast majority of sequences obtained grouped in genotype South America-I, which includes isolates from Argentina and Uruguay, with the exception of a sample similar to the vaccine strain Rockborn. Phylogenetic analysis suggests the presence of at least seven subgenotypes belonging to South America-I genotype, circulating in this continent. The group South America-II consists only of isolates from Argentina. Furthermore, it is proposed that this group and clades Rockborn-like and Europe Wildlife are denominated subgenotypes within a single genotype.

Advisors/Committee Members: Canal, Cláudio Wageck.

Subjects/Keywords: Cinomose; Dog; Doenças: : cães; Canine distemper; Genótipo; Genotype; South america; Virologia veterinaria : Caes; Brasil; Diagnosis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Budaszewski, R. d. F. (2013). Análise filogenética do vírus da cinomose canina no Brasil. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/69909

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Budaszewski, Renata da Fontoura. “Análise filogenética do vírus da cinomose canina no Brasil.” 2013. Thesis, Universidade do Rio Grande do Sul. Accessed March 05, 2021. http://hdl.handle.net/10183/69909.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Budaszewski, Renata da Fontoura. “Análise filogenética do vírus da cinomose canina no Brasil.” 2013. Web. 05 Mar 2021.

Vancouver:

Budaszewski RdF. Análise filogenética do vírus da cinomose canina no Brasil. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2013. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10183/69909.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Budaszewski RdF. Análise filogenética do vírus da cinomose canina no Brasil. [Thesis]. Universidade do Rio Grande do Sul; 2013. Available from: http://hdl.handle.net/10183/69909

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Michelle Gomes Barreto. Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose.

Degree: 2006, Universidade Federal Rural do Rio de Janeiro

URL: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=150

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Foi realizado um estudo comparativo do diagnóstico da cinomose pelas técnicas de Imunofluorescência Direta (IFD), Imunofluorescência Indireta (IFI) e Coloração de Sellers em amostras de… (more)

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Foi realizado um estudo comparativo do diagnóstico da cinomose pelas técnicas de Imunofluorescência Direta (IFD), Imunofluorescência Indireta (IFI) e Coloração de Sellers em amostras de tecido nervoso de cães e de animais silvestres que morreram com suspeita clínica da virose. Foram utilizados 118 amostras de Sistema nervoso central (SNC) de cães domésticos e de 3 animais silvestres , dois gambás e um mico, utilizando-se Corno de Ammon (CA), Cerebelo (CB) e Tronco Encefálico (TE). O TE foi à região de maior porcentagem de positivos, seguido do CA. A comparação entre a Coloração de Sellers, e a IFD, revelou uma maior sensibilidade nesta última. Na IFI, observamos que para a realização da técnica torna-se necessário à utilização de material fresco. Tendo em vista a utilização das 117 amostras em estado de autólise apresentaram resultados negativos e apenas 1 não autolisado, teve seu resultado positivo nas 3 regiões cerebrais (CA, CB e TE). Não foi possível a comparação com a técnica de IFI, porque nesse trabalho, a técnica só foi possível em materiais conservados, com a vantagem de uma leitura mais fácil. Nesse trabalho foi detectado também cinomose em um gambá pela técnica de IFD.

It was performed a study comparative in the diagnostic of the canine distemper through techniques of Direct Immunofluorescence (IFD), Indirect Immunofluorescence (IFI) and Stain Sellers in samples of nervous tissue of dogs and wild animals that died with suspicion clinical of the viruse. Were utilized 118 samples of central nervous system (SNC) of domestic dogs and 3 wild animals, 2 skunks and 1 monkey, utilizing Ammons horn (CA), cerebellum (CB) and brain stem (TE). The TE was the region of larger percentage of positive, following of CA. The comparation between Stain Sellers and IFD, this last demonstrated a large sensitive. The IFI observed what to the realization of the technique was necessary the utilization of fresh materials. The utilization of the 117 samples in conditions of autolysis presented negative result. However 1 sample not autolysate, it was result positive in the 3 brain regions (CA, CB, TE). It was not possible the comparative with the technique of IFI, because in the work the technique alone was possible in materials conserved, with the advantage of a read more easy. In the work was detected also canine distemper in a skunk through technique of IFD.

Advisors/Committee Members: Claúdio de Moraes Andrade.

Subjects/Keywords: MEDICINA VETERINARIA; cinomose; imunofluorescência; Coloração de Sellers; canine distemper; immunofluorescence; Stain Sellers

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Barreto, M. G. (2006). Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose. (Thesis). Universidade Federal Rural do Rio de Janeiro. Retrieved from http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=150

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Barreto, Michelle Gomes. “Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose.” 2006. Thesis, Universidade Federal Rural do Rio de Janeiro. Accessed March 05, 2021. http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=150.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Barreto, Michelle Gomes. “Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose.” 2006. Web. 05 Mar 2021.

Vancouver:

Barreto MG. Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose. [Internet] [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2006. [cited 2021 Mar 05]. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=150.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Barreto MG. Estudo Comparativo das técnicas de Imunofluorescência Direta, Imunofluorescência Indireta e Coloração de Sellers em amostra de tecido nervoso de cães e de animais silvestres para o diagnóstico da cinomose. [Thesis]. Universidade Federal Rural do Rio de Janeiro; 2006. Available from: http://bdtd.ufrrj.br//tde_busca/arquivo.php?codArquivo=150

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

6. Clodomir Guedes Lopes Júnior. Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco.

Degree: 2006, Universidade Federal Rural de Pernambuco

URL: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=872

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A Cinomose é uma enfermidade infecciosa que acomete cães, que afeta o sistema respiratório, gastrointestinal, e nervoso que se caracteriza por imunossupressão. O objetivo do… (more)

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A Cinomose é uma enfermidade infecciosa que acomete cães, que afeta o sistema respiratório, gastrointestinal, e nervoso que se caracteriza por imunossupressão. O objetivo do presente estudo foi estudar as contagens das células vermelhas e brancas, padrões de albumina, proteína plasmática total, alanino aminotransferase (ALT),aspartato aminotransferase (AST), glicose, creatina e uréia em 37 cães avaliados. Em outra condição foram estudados 4 cães com 16 analises em diferentes tempos da infecção (0 , 7 , 14 , e 21 dias após diagnóstico da doença). O resultado demonstrou anemia normocítica e normocrômica (67%), na contagem apresentou linfocitopenia (65%), trombocitopenia (30%) hipoglicemia (67%), AST (TGO) aumentada (78%), ALT (TGP) aumentada (21%) neste presente estudo. A eletroforese das proteínas revelou alteração, com elevação da gama globulina e decréscimo nas alfas globulinas. Não foi observada diferença significativa entre as contagens das séries branca e vermelha, proteínas plasmática total e bioquímica avaliados estatisticamente. Os exames laboratoriais são importantes como recursos no diagnóstico da cinomose, principalmente as alterações hematológicas, bioquímicas e eletroforéticas, podem auxiliar na conduta terapêutica desta enfermidade.

Canine distemper is an important viral disease in dogs that affects the respiratory, gastrointestinal, and also central nervous characterized by immunosuppression. The goal of this work was to study the counting of red blood and white blood cells, albumin, plasmatic total protein, alanine aminotransferase (ALT), aspartate aminotransferase (AST), glucose, creatinine and ureia patterns in 37 dogs from differents breeds. On the other hand, studies were performed on a total of 16 analysis from four dogs at different times following of infection (1th, 7th, 14th and 21th day after the diagnosis of the disease) The results showed the Normocytic-normochromic anemia in 67% of animals and the white blood cell couting present lymphocytopenia , thrombocytopenia in 65% and 30% respectivelly. Hypoglycemia was observed in 67% and high AST and ALT values were recorderd in 78% and 21 % in this study. Serum protein electrophoresis revealed alterations in serum components with elevation in the gamma region and decrease of alpha-globulins regions. It was not observed a significative difference between counting of red blood and white blood cells, plasmatic total protein and seric biochemistry evaluated statistics. The exams laboratories are important as resources in the diagnosis of the distemper, mainly the hematological alterations, biochemistries and electrophoresis, can aid in the therapeutic conduct of this illness.

Advisors/Committee Members: Lúcio Esmeraldo Honorio de Melo, Miriam Nogueira Teixeira, Evilda Rodrigues de Lima, Joaquim Evêncio Neto.

Subjects/Keywords: Cinomose; Cão; Hemograma; Eletroforese; Diagnóstico; MEDICINA VETERINARIA; Canine distemper; Dog; Hemogram; Electrophoresis; Diagnostic

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Júnior, C. G. L. (2006). Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco. (Thesis). Universidade Federal Rural de Pernambuco. Retrieved from http://200.17.137.108/tde_busca/arquivo.php?codArquivo=872

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Júnior, Clodomir Guedes Lopes. “Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco.” 2006. Thesis, Universidade Federal Rural de Pernambuco. Accessed March 05, 2021. http://200.17.137.108/tde_busca/arquivo.php?codArquivo=872.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Júnior, Clodomir Guedes Lopes. “Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco.” 2006. Web. 05 Mar 2021.

Vancouver:

Júnior CGL. Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco. [Internet] [Thesis]. Universidade Federal Rural de Pernambuco; 2006. [cited 2021 Mar 05]. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=872.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Júnior CGL. Avaliação do perfil hematológico, bioquímico e eletroforese das proteínas séricas de cães com cinomose atendidos no Hospital Veterinário da Universidade Federal Rural de Pernambuco. [Thesis]. Universidade Federal Rural de Pernambuco; 2006. Available from: http://200.17.137.108/tde_busca/arquivo.php?codArquivo=872

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

7. Bellan, Steven Edward. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.

Degree: Environmental Science, Policy, & Management, 2012, University of California – Berkeley

URL: http://www.escholarship.org/uc/item/4xx9c4f0

► The goal of epidemiology is to identify the biological, behavioral, and environmental causes of health outcomes or diseases and apply this knowledge to the development… (more)

Subjects/Keywords: Biology; Health sciences; Animal diseases; anthrax; canine distemper virus; HIV; jackal; rabies; zebra

9 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bellan, S. E. (2012). Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. (Thesis). University of California – Berkeley. Retrieved from http://www.escholarship.org/uc/item/4xx9c4f0

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bellan, Steven Edward. “Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.” 2012. Thesis, University of California – Berkeley. Accessed March 05, 2021. http://www.escholarship.org/uc/item/4xx9c4f0.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bellan, Steven Edward. “Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans.” 2012. Web. 05 Mar 2021.

Vancouver:

Bellan SE. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. [Internet] [Thesis]. University of California – Berkeley; 2012. [cited 2021 Mar 05]. Available from: http://www.escholarship.org/uc/item/4xx9c4f0.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bellan SE. Applications of Data-driven Modeling to Infectious Diseases in Africa: Anthrax in Wildlife and HIV in Humans. [Thesis]. University of California – Berkeley; 2012. Available from: http://www.escholarship.org/uc/item/4xx9c4f0

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Amaral, Helena Arantes do. Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica.

Degree: PhD, Clínica Veterinária, 2007, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/10/10136/tde-28092007-163234/ ;

►

Diferentes amostras biológicas foram avaliadas (zaragatoa ocular, genital, urina e células mononucleares do sangue periférico) pela RT-PCR em 50 cães com sintomas neurológicos compatíveis como… (more)

▼

Diferentes amostras biológicas foram avaliadas (zaragatoa ocular, genital, urina e células mononucleares do sangue periférico) pela RT-PCR em 50 cães com sintomas neurológicos compatíveis como cinomose, na presença ou não de outros sintomas sistêmicos. O gene da nucleoproteína do vírus da cinomose foi detectado em 43 das 50 amostras avaliadas. Considerando apenas os animais com resultado positivos pela hemi-nested - PCR, os sintomas neurológicos observados com freqüência maior que 50%, foram mioclonia e alteração locomotora (maioria dos cães evoluiu a tetraparesia); convulsão e vocalização foram observados em 32% dos casos Outros sintomas sistêmicos, sintomas oculares, respiratórios ou digestivos, prévios ou associados aos sintomas neurológicos, foram observados em 82% dos cães. Também observou-se hiperqueratose nasal ou de coxins em 44% dos casos. Somente 20% dos animais positivos haviam sido vacinados contra o vírus da cinomose. Zaragatoas genitais forneceram maior número de resultados positivos (40), seguidos por zaragatoas oculares e urina (37) e células mononucleares do sangue periférico (34). A coleta associada de duas amostras biológicas (zaragatoa genital e urina) por animal aumentou a possibilidade de detecção de animais positivos, principalmente nos casos de cães suspeitos que não apresentaram sintomas respiratórios, gastrintestinais e oculares, assim como nos animais vacinados e cronicamente infectados ou convalescentes.

Using Reverse transcription-PCR assay, different biological samples were avaliabled (conjunctival and genital swabs, urine and peripheral blood mononuclear cells) from dogs with or with no extraneural signs prior to or accompanying the neurologic signs. Canine distemper nucleoprotein were detected in 43 from 50 dogs availabled by hemi-nested-PCR. Considering just dogs with distemper confirmed by hemi-nested PCR, gait abnormalities (most commonly tetraparesis) and myoclonus were the neurological signs observed in over 50%; vocalizing and seizures occurred in 32%. Other systemic signs (respiratory, gastroenteric or ocular signs). preceding or associated to neurological signs, occurred in 82% of dogs Hyperkeratosis of the footpads or nose were observed in 44 % of the cases. Only (20%) were vaccinated against canine distemper. A greater number of positive results were obtained from genital swabs (40), followed by conjuctival swabs and urine (37) and PBMCs (33). Sensitivity of detection positive results were increased by using two clinical samples association (genital swab and urine), specially in dogs that had not shown extra neural signs, vaccinate dogs or during the convalescent and late stage of canine distemper.

Advisors/Committee Members: Larsson, Maria Helena Matiko Akao.

Subjects/Keywords: Amostras biológicas; Cães; Canine distemper; Cinomose canina; Clinical samples; Dogs; PCR; PCR; Urina; Urine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Amaral, H. A. d. (2007). Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/10/10136/tde-28092007-163234/ ;

Chicago Manual of Style (16^th Edition):

Amaral, Helena Arantes do. “Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica.” 2007. Doctoral Dissertation, University of São Paulo. Accessed March 05, 2021. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-28092007-163234/ ;.

MLA Handbook (7^th Edition):

Amaral, Helena Arantes do. “Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica.” 2007. Web. 05 Mar 2021.

Vancouver:

Amaral HAd. Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica. [Internet] [Doctoral dissertation]. University of São Paulo; 2007. [cited 2021 Mar 05]. Available from: http://www.teses.usp.br/teses/disponiveis/10/10136/tde-28092007-163234/ ;.

Council of Science Editors:

Amaral HAd. Detecção do vírus da cinomose pela técnica de RT-PCR em cães com sintomatologia neurológica. [Doctoral Dissertation]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/10/10136/tde-28092007-163234/ ;

9. Hayashi, Erika Midori Kida. Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás.

Degree: Mestrado, Epidemiologia Experimental Aplicada às Zoonoses, 2013, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/10/10134/tde-29042013-153257/ ;

►

A conservação dos animais selvagens de vida livre é ameaçada pela fragmentação de habitat, caça, diminuição de presas e, em menor escala pela ocorrência de… (more)

▼

A conservação dos animais selvagens de vida livre é ameaçada pela fragmentação de habitat, caça, diminuição de presas e, em menor escala pela ocorrência de doenças infecciosas. Reconhecendo a importância das doenças para a conservação, e considerando que o crescimento da população humana no entorno de áreas protegidas propicia o aumento do contato de animais domésticos e selvagens, o presente estudo teve como objetivo pesquisar a exposição de carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas (PNE), Goiás à cinomose, parvovirose, brucelose e brucelose canina. Entre as espécies de carnívoros selvagens amostradas estão o lobo-guará, cachorro-do-mato, raposinha-do-campo, onça-parda, jaguatirica, gato-palheiro, gatomourisco, jaratataca e quati. Foram realizados os testes de soroneutralização, inibição de hemaglutinação, imunodifusão em gel ágar e PCR, para cinomose, parvovirose, brucelose canina e brucelose, respectivamente. Lobos-guará (12,7%, n=9), cachorros-do-mato (11,6%, n=7), jaguatiricas (18,2%, n=2) e cães domésticos (71,4%, n=25) foram expostos à cinomose. Todas as espécies de carnívoros selvagens amostradas, com exceção do quati, sendo 40,4% (n=65) dos indivíduos, e 37,1% (n=13) dos cães domésticos foram expostos à parvovirose. Apenas o lobo-guará (1,67%, n=2) foi exposto à brucelose canina e a raposinha-do-campo à Brucella spp. (1,47%, n=1). Este é o primeiro relato da exposição de gato-palheiro, gatomourisco e jaratataca ao parvovírus, e de lobo-guará à Brucella canis. A cinomose e a parvovirose merecem atenção no PNE pela possibilidade de envolvimento de cães domésticos na sua transmissão, embora não possa ser comprovada no presente estudo. A brucelose, no momento, parece não ser uma ameaça sanitária para as populações de carnívoros do PNE.

The conservation of free ranging wildlife is threatened by habitat fragmentation, hunting, decrease of prey and, to a lesser extent by the occurrence of infectious diseases. Recognizing the diseases importance for conservation, and considering that the increase of human population around protected areas provides increased contact with domestic and wild animals, the present study aimed to investigate the exposure of free ranging wild carnivores and domestic dogs in the region of Emas National Park (ENP), Goiás, Brazil for canine distemper virus (CDV), parvovirus, brucellosis and canine brucellosis. Among the species of wild carnivores sampled are the maned wolf, crab-eating fox, hoary fox, puma, ocelot, pampas cat, jaguarondi, skunk and coati. The tests performed for CDV, parvovirus, canine brucellosis and brucellosis tests were the serum neutralization test, hemagglutination inhibition, agar gel immunodiffusion and PCR, respectively. Maned wolves (12.7%, n = 9), crab-eating foxes (11.6%, n = 7), ocelots (18.2%, n = 2) and domestic dogs (71.4%, n = 25) were exposed to CDV. All species of wild carnivores sampled, except coatis, being 40.4% (n = 65) of individuals, and 37.1% (n = 13) of domestic dogs were exposed to…

Advisors/Committee Members: Ferreira Neto, José Soares.

Subjects/Keywords: Brucellosis; Brucelose; Cães domésticos; Canine distemper; Carnívoros selvagens; Cinomose; Domestic dogs; Parvovirose; Parvovirus; Wild carnivores

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hayashi, E. M. K. (2013). Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/10/10134/tde-29042013-153257/ ;

Chicago Manual of Style (16^th Edition):

Hayashi, Erika Midori Kida. “Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás.” 2013. Masters Thesis, University of São Paulo. Accessed March 05, 2021. http://www.teses.usp.br/teses/disponiveis/10/10134/tde-29042013-153257/ ;.

MLA Handbook (7^th Edition):

Hayashi, Erika Midori Kida. “Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás.” 2013. Web. 05 Mar 2021.

Vancouver:

Hayashi EMK. Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás. [Internet] [Masters thesis]. University of São Paulo; 2013. [cited 2021 Mar 05]. Available from: http://www.teses.usp.br/teses/disponiveis/10/10134/tde-29042013-153257/ ;.

Council of Science Editors:

Hayashi EMK. Pesquisa de cinomose, parvovirose e brucelose em carnívoros selvagens de vida livre e cães domésticos da região do Parque Nacional das Emas, Goiás. [Masters Thesis]. University of São Paulo; 2013. Available from: http://www.teses.usp.br/teses/disponiveis/10/10134/tde-29042013-153257/ ;

University of Pretoria

10. Haig, D.A. Canine distemper : immunisation with avianised virus.

Degree: DVSc, Companion Animal Clinical Studies, 1953, University of Pretoria

URL: http://hdl.handle.net/2263/61731

No abstract

Subjects/Keywords: UCTD; Dogs – Virus doseases; Canine distemper

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Haig, D. A. (1953). Canine distemper : immunisation with avianised virus. (Doctoral Dissertation). University of Pretoria. Retrieved from http://hdl.handle.net/2263/61731

Chicago Manual of Style (16^th Edition):

Haig, D A. “Canine distemper : immunisation with avianised virus.” 1953. Doctoral Dissertation, University of Pretoria. Accessed March 05, 2021. http://hdl.handle.net/2263/61731.

MLA Handbook (7^th Edition):

Haig, D A. “Canine distemper : immunisation with avianised virus.” 1953. Web. 05 Mar 2021.

Vancouver:

Haig DA. Canine distemper : immunisation with avianised virus. [Internet] [Doctoral dissertation]. University of Pretoria; 1953. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/2263/61731.

Council of Science Editors:

Haig DA. Canine distemper : immunisation with avianised virus. [Doctoral Dissertation]. University of Pretoria; 1953. Available from: http://hdl.handle.net/2263/61731

University of Missouri – Columbia

11. Pardo, Ingrid D. R. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.

Degree: 2006, University of Missouri – Columbia

URL: http://hdl.handle.net/10355/4542

► In 2004, dogs with clinical signs suggestive of viral disease known as canine distemper virus (CD) were referred to the University of Missouri Veterinary Diagnostic… (more)

Subjects/Keywords: Canine distemper – Genetic aspects; Canine distemper – Genetic aspects; Canine distemper virus – Genetic aspects; Canine distemper virus – Genetic aspects; Dogs – Diseases – Genetic aspects; Dogs – Diseases – Genetic aspects

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pardo, I. D. R. (2006). Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. (Thesis). University of Missouri – Columbia. Retrieved from http://hdl.handle.net/10355/4542

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pardo, Ingrid D R. “Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.” 2006. Thesis, University of Missouri – Columbia. Accessed March 05, 2021. http://hdl.handle.net/10355/4542.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pardo, Ingrid D R. “Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs.” 2006. Web. 05 Mar 2021.

Vancouver:

Pardo IDR. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. [Internet] [Thesis]. University of Missouri – Columbia; 2006. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10355/4542.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pardo IDR. Phylogenetic characterization of canine distemper viruses detected in naturally infected North American dogs. [Thesis]. University of Missouri – Columbia; 2006. Available from: http://hdl.handle.net/10355/4542

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

12. Fung, Hou-Ming Lillian. Community level canine health assessment.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/28267

► Domestic dogs often serve as reservoir hosts for many zoonotic and wildlife pathogens. This study evaluates the role dog health plays in infectious disease transmission,… (more)

Subjects/Keywords: Zoonoses; Chagas disease; Trypanosoma cruzi; Intestinal helminths; Neglected Tropical Diseases; Canine Distemper Virus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fung, H. L. (2014). Community level canine health assessment. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/28267

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fung, Hou-Ming Lillian. “Community level canine health assessment.” 2014. Thesis, University of Georgia. Accessed March 05, 2021. http://hdl.handle.net/10724/28267.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fung, Hou-Ming Lillian. “Community level canine health assessment.” 2014. Web. 05 Mar 2021.

Vancouver:

Fung HL. Community level canine health assessment. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10724/28267.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fung HL. Community level canine health assessment. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/28267

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Montana

13. Weckworth, Julie Kay. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.

Degree: PhD, 2018, University of Montana

URL: https://scholarworks.umt.edu/etd/11221

► The impact of emerging infectious diseases (EIDs) on the health and persistence of wildlife populations is an increasing conservation concern. Large carnivores are particularly… (more)

▼ The impact of emerging infectious diseases (EIDs) on the health and persistence of wildlife populations is an increasing conservation concern. Large carnivores are particularly vulnerable to EID impacts because they often occur in small, isolated populations with demographic and genetic challenges to long-term persistence. Ecological forces that isolate carnivore populations, e.g. agricultural intensification, simultaneously increase the probability of disease exposure from domestic species and can amplify population susceptibility to infection. Canine distemper virus emerged as a conservation threat to African lions when an explosive epizootic caused the death or disappearance of a third of the Serengeti lion population in 1994. This same lion population was exposed to CDV on several other occasions without overt clinical infection. For my dissertation, I investigated ecological, epidemiological, and evolutionary factors contributing to the emergence and outcome of CDV infection in this globally important population. Based on phylodynamic analyses of annotated sequence data I found that the lethal outbreak in 1994 was likely catalyzed by a single spillover event from a canid reservoir, and fueled by repeated transmissions from non-canid hosts, e.g. spotted hyenas. Distinct genotypes were found in canid and non-canid hosts suggesting that there is a host barrier to CDV spillover, which might limit lethal outbreaks in lions. Expanding the spatiotemporal scope of the phylogenetic analysis I found that Serengeti lions were not epidemiologically connected to other carnivore populations at the regional or continental scale. Recurrent CDV infection in Serengeti lions was likely due to local persistence in the domestic and/or wild carnivore community. Finally, based on phylogenetic and selection analyses I identified 25 candidate markers in the CDV genome potentially associated with the pathogenicity of infection in lions during the 1994 outbreak. These were mostly found in functional domains related to transcription and replication, and viral egress, implicating these processes as possible barriers to disease in lions. Mutations at two of the markers were shared with two CDV outbreaks in North America that caused clinical infection in African lions. Surveillance for these two mutations in circulating strains may inform CDV risk assessment in lion populations of conservation concern.

Subjects/Keywords: African lion; Canine distemper virus; Cross-species transmission; Disease spillover; Evolutionary genetics; Molecular epidemiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Weckworth, J. K. (2018). ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. (Doctoral Dissertation). University of Montana. Retrieved from https://scholarworks.umt.edu/etd/11221

Chicago Manual of Style (16^th Edition):

Weckworth, Julie Kay. “ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.” 2018. Doctoral Dissertation, University of Montana. Accessed March 05, 2021. https://scholarworks.umt.edu/etd/11221.

MLA Handbook (7^th Edition):

Weckworth, Julie Kay. “ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS.” 2018. Web. 05 Mar 2021.

Vancouver:

Weckworth JK. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. [Internet] [Doctoral dissertation]. University of Montana; 2018. [cited 2021 Mar 05]. Available from: https://scholarworks.umt.edu/etd/11221.

Council of Science Editors:

Weckworth JK. ECOLOGY, EPIDEMIOLOGY, AND EVOLUTIONARY GENETICS OF CANINE DISTEMPER VIRUS SPILLOVER IN AFRICAN LIONS. [Doctoral Dissertation]. University of Montana; 2018. Available from: https://scholarworks.umt.edu/etd/11221

Universidade Federal de Santa Maria

14. Renata Dezengrini. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.

Degree: 2006, Universidade Federal de Santa Maria

URL: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

► O presente trabalho relata um inquérito sorológico das principais infecções víricas de cães em Santa Maria, RS, Brasil e a obtenção de linhagens celulares de… (more)

▼ O presente trabalho relata um inquérito sorológico das principais infecções víricas de cães em Santa Maria, RS, Brasil e a obtenção de linhagens celulares de origem canina, suína e leporina resistentes ao vírus da Diarréia Viral Bovina (BVDV). As infecções pelo vírus da cinomose (CDV), parvovírus (CPV), adenovírus (CAV) e coronavírus (CCoV) são importantes causas de morbidade e de mortalidade em cães em todo o mundo. Com o objetivo de determinar a prevalência de anticorpos contra esses vírus na população canina da cidade de Santa Maria, coletou-se amostras de sangue de 817 cães não-vacinados, em 14 bairros. Estas foram testadas pela técnica de soroneutralização (CDV, CAV e CCoV) ou inibição da hemaglutinação (CPV). Anticorpos específicos contra o CDV foram detectados em 27,3% (223/817) das amostras, contra o CPV em 68,7% (561/817), contra o CAV em 43% (353/817) e contra o CCoV em 50,4% (412/817) dos cães. Esses resultados demonstram que esses vírus estão difundidos na população canina dos bairros da cidade. Por outro lado, demonstram também que uma parte considerável da população é soronegativa e, portanto está desprotegida contra esses agentes, indicando a necessidade de se ampliar os programas de vacinação para essas infecções. Durante a padronização das técnicas sorológicas e expansão dos cultivos celulares para amplificação dos vírus, detectou-se a contaminação da linhagem de células caninas MDCK com o BVDV, o principal vírus contaminante de cultivos celulares. A contaminação inadvertida de cultivos celulares com o BVDV pode representar um sério problema para o diagnóstico virológico, pesquisa e produção de imunobiológicos. A segunda parte dessa dissertação descreve a produção e caracterização de três linhagens celulares resistentes ao BVDV, obtidas a partir das células parentais de origem canina (MDCK), suína (PK-15) e leporina (RK-13) que estavam contaminadas com o BVDV. Essas células foram submetidas a quatro ciclos de infecção com uma cepa citolítica de BVDV. As células que sobreviveram a infecção lítica foram clonadas, expandidas e testadas para a sua susceptibilidade ao BVDV e outros vírus de interesse. A resistência ao BVDV foi investigada pela pesquisa de antígenos virais por imunofluorescência indireta e por cocultivo com células susceptíveis após a inoculação do vírus em altos títulos. As três linhagens celulares demonstraram ser resistentes a três cepas-padrão (Singer, NADL e Oregon) e a 10 isolados de campo do BVDV. A inoculação do BVDV nessas células com uma multiplicidade de infecção de 10 DICC50/célula resultou em freqüências de infecção de <10-5 para as células MDCK-R e PK-15R; e de 3,3x10-4 para as células RK-13R. Comparando-se com as células parentais, verificou-se que as linhagens resistentes são >10.000 (MDCK-R), >20.000 (PK-15R) e 600 (RK-13R) vezes menos susceptíveis ao BVDV. A inoculação do vírus nas células resistentes na presença de polietilenoglicol (PEG) resultou em um aumento na susceptibilidade dessas células na ordem de >437 (MDCK-R), >346 (PK-15R) e 87 vezes (RK-13R). Esses… Advisors/Committee Members: Eduardo Furtado Flores, Luciane Teresinha Lovato.

Subjects/Keywords: resistant cells; células resistentes; contaminação celular; coronavírus canino; adenovírus canino; parvovírus canino; vírus da cinomose; MEDICINA VETERINARIA; canine adenovirus; canine parvovirus; canine distemper virus; canine coronavirus; cell contamination

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dezengrini, R. (2006). SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. (Thesis). Universidade Federal de Santa Maria. Retrieved from http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dezengrini, Renata. “SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.” 2006. Thesis, Universidade Federal de Santa Maria. Accessed March 05, 2021. http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dezengrini, Renata. “SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA.” 2006. Web. 05 Mar 2021.

Vancouver:

Dezengrini R. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. [Internet] [Thesis]. Universidade Federal de Santa Maria; 2006. [cited 2021 Mar 05]. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dezengrini R. SOROPREVALÊNCIA DE INFECÇÕES VÍRICAS EM CÃES DE SANTA MARIA, RS; SELEÇÃO E CARACTERIZAÇÃO DE LINHAGENS CELULARES RESISTENTES AO VÍRUS DA DIARRÉIA VIRAL BOVINA. [Thesis]. Universidade Federal de Santa Maria; 2006. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=1189

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Technical University of Lisbon

15. Castanheira, Pedro Joaquim de Carvalho Mendes. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.

Degree: 2012, Technical University of Lisbon

URL: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

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Dissertação de Mestrado Integrado em Medicina Veterinária

As infeções pelo parvovírus canino (CPV), vírus da esgana canina (CDV) e coronavírus canino (CCoV) são importantes causas… (more)

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Dissertação de Mestrado Integrado em Medicina Veterinária

As infeções pelo parvovírus canino (CPV), vírus da esgana canina (CDV) e coronavírus canino (CCoV) são importantes causas de morbilidade e de mortalidade em cães de todo o mundo. Contudo, aparentemente não se conhece a sua incidência e prevalência no arquipélago de Cabo Verde. Para determinar a prevalência dessas infeções na população canina da cidade de Vila do Maio, situada na ilha do Maio, foram colhidas amostras a partir cães errantes desse local em dois períodos distintos: no ano de 2010 obtiveram-se 53 zaragatoas retais e em 2011 colheram-se 93 zaragatoas retais e 88 amostras de sangue, existindo 56 animais coincidentes nos dois tipos de amostra. Do total de 125 cães amostrados neste último ano apenas 2 eram vacinados. Testou-se a presença de ácido nucleico viral por real-time PCR e real-time RT-PCR a partir das zaragatoas e analisou-se a presença de anticorpos contra CPV e CDV nas amostras de sangue. Em relação a 2010, detetou-se ácido nucleico viral em 43,3% (23/53) das amostras para CPV, 11,3% (6/53) para CDV e 1,9% (1/53) para CCoV. Em 2011, a prevalência de CPV foi de 44,1% (41/93), 0% para CDV e 1,1% (1/93) para CCoV. Ainda neste ano, anticorpos contra o CPV foram detetados em 71,6% (63/88) das amostras de sangue e a seroprevalência no caso do CDV foi de 51,1% (45/88). A presença de anticorpos anti-CPV foi significativamente superior nos cães mais velhos e observou-se uma tendência crescente de seropositividade com o aumento da idade no caso do CDV, embora não fosse estatisticamente significativo. Não se registaram diferenças de seroprevalência em relação ao género dos animais. Este trabalho demonstra a importância da vigilância epidemiológica molecular em populações de animais errantes e domésticos das cidades, uma vez que o seu elevado número possibilita a disseminação e manutenção dos vírus nestes locais, que pode conduzir a uma elevada mortalidade em populações com reduzidas taxas de vacinação. Para além disso, estes animais podem constituir reservatórios das doenças, havendo possibilidade de transmissão às populações de animais selvagens através de contactos ocasionais. Seria importante identificar a fauna silvestre suscetível da ilha do Maio, para se avaliar até que ponto os vírus que se encontram em Vila do Maio podem constituir um perigo para esses animais.

ABSTRACT - VIROLOGICAL SURVEY IN STRAY DOGS OF VILA DO MAIO, CAPE VERDE - Infections caused by canine parvovirus (CPV), canine distemper virus (CDV) and canine coronavirus (CCoV) are important causes of morbidity and mortality in dogs worldwide. However, it seems that the incidence and prevalence of these viruses is unknown in the archipelago of Cape Verde. To determine the prevalence of these infections in Vila do Maio canine population, located in Maio island, samples were collected from stray dogs in two distinct periods: in 2010, fifty three rectal swabs were obtained and in 2011 a total of 93 rectal swabs and 88 blood samples were collected, and 56 animals were coincident in…

Advisors/Committee Members: Duarte, Ana Isabel Simões Pereira.

Subjects/Keywords: Rastreio virológico; epidemiologia molecular; parvovírus canino; vírus da esgana canina; coronavírus canino; Cabo Verde; virological survey; molecular epidemiology; canine parvovirus; canine distemper virus; canine coronavirus; Cape Verde

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Castanheira, P. J. d. C. M. (2012). Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. (Thesis). Technical University of Lisbon. Retrieved from http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Castanheira, Pedro Joaquim de Carvalho Mendes. “Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.” 2012. Thesis, Technical University of Lisbon. Accessed March 05, 2021. http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Castanheira, Pedro Joaquim de Carvalho Mendes. “Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde.” 2012. Web. 05 Mar 2021.

Vancouver:

Castanheira PJdCM. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. [Internet] [Thesis]. Technical University of Lisbon; 2012. [cited 2021 Mar 05]. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Castanheira PJdCM. Rastreio virológico de cães errantes da cidade de Vila do Maio, Cabo Verde. [Thesis]. Technical University of Lisbon; 2012. Available from: http://www.rcaap.pt/detail.jsp?id=oai:www.repository.utl.pt:10400.5/4835

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Humboldt State University

16. Sanchez, Jessica N. Spatial ecology of disease spread in the island fox.

Degree: 2012, Humboldt State University

URL: http://hdl.handle.net/2148/1045

► Diseases are potential threats to wildlife populations worldwide, and recent epidemics have demonstrated their far-reaching impacts. The spread of directly transmitted pathogens is influenced by… (more)

▼ Diseases are potential threats to wildlife populations worldwide, and recent epidemics have demonstrated their far-reaching impacts. The spread of directly transmitted pathogens is influenced by host contact rates, and host density can alter these contact rates by changing the spatial distribution of host home ranges. I explored how host density might affect the spread of directly transmitted pathogens in Channel Island foxes (Urocyon littoralis) through changes in contact rates, home range size and overlap. I tracked 40 radio-collared foxes at four sites on San Clemente Island, which ranged in density from 2.8??1.28 to 42.8??9.43 foxes/km2. Thirty foxes wore collars that also contained proximity loggers. More overlap correlated with higher rates of contact between neighbors. Foxes at high densities had more neighbors with overlapping home ranges but not an increase in the amount of pair-wise overlap or contact between individual neighbors. I used these home range and contact data to parameterize a spatially explicit model of rabies and canine distemper spread in island foxes. Modeled fox densities, home range sizes and degree of overlap, and contact rates approximated those measured on San Clemente Island. I examined how host density at the point of disease introduction and different vaccination strategies (i.e., no vaccination, random vaccination, or firewall/core area vaccination) might affect disease dynamics. In model simulations, canine distemper spread quicker, infected more animals, and caused a greater reduction in the fox population than rabies due to differences in the length of the prepatent and infectious periods. The introduction of either pathogen to areas of high fox density resulted in more rapid transmission than if the pathogen was introduced at lower densities. Random vaccination was generally the more successful strategy for reducing the number of infected or dead animals from both diseases, and may be the preferable strategy for San Clemente Island. The model parameters with the greatest proportional effect on output were fox contact rates, virus transmissibility, background transmission rate, and the length of the prepatent and infectious periods. This study was the first time island fox contact rates were directly measured and compared to density and home range overlap, and it confirms that overlap is a reliable index of the amount of direct contact between island foxes. Model results can be used to advise conservation efforts aimed at preventing and responding to disease outbreaks in island foxes. Advisors/Committee Members: Hudgens, Brian.

Subjects/Keywords: Channel Islands; Urocyon littoralis; Modeling; Rabies; Canine distemper; Contact rates; Home range; Disease spread; Population density; Island fox

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sanchez, J. N. (2012). Spatial ecology of disease spread in the island fox. (Thesis). Humboldt State University. Retrieved from http://hdl.handle.net/2148/1045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sanchez, Jessica N. “Spatial ecology of disease spread in the island fox.” 2012. Thesis, Humboldt State University. Accessed March 05, 2021. http://hdl.handle.net/2148/1045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sanchez, Jessica N. “Spatial ecology of disease spread in the island fox.” 2012. Web. 05 Mar 2021.

Vancouver:

Sanchez JN. Spatial ecology of disease spread in the island fox. [Internet] [Thesis]. Humboldt State University; 2012. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/2148/1045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sanchez JN. Spatial ecology of disease spread in the island fox. [Thesis]. Humboldt State University; 2012. Available from: http://hdl.handle.net/2148/1045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade Federal de Santa Maria

17. Marcia Cristina da Silva. NEUROPATOLOGIA DA CINOMOSE CANINA.

Degree: 2009, Universidade Federal de Santa Maria

URL: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=2563

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A cinomose é uma das doenças virais mais prevalentes em cães. Muitos cães são diagnosticados com a doença diariamente em clínicas e hospitais veterinários de… (more)

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A cinomose é uma das doenças virais mais prevalentes em cães. Muitos cães são diagnosticados com a doença diariamente em clínicas e hospitais veterinários de todo o país. A forma neurológica da cinomose é fatal na grande maioria das vezes, e a confirmação do diagnóstico clínico através do exame histopatológico se faz necessária em muitos casos. A encefalite por cinomose representa a principal causa de morte ou razão para eutanásia de cães necropsiados no Laboratório de Patologia Veterinária (LPV) da Universidade Federal de Santa Maria (UFSM). Com isso, o grande número de casos de cinomose arquivados no LPVUFSM proporcionou a realização de um estudo retrospectivo de 620 casos da forma neurológica da doença que serviu como base para a realização de um estudo neurohistopatológico prospectivo. O presente estudo tem como objetivo realizar uma investigação histopatológica detalhada das alterações no sistema nervoso central (SNC) de cães com cinomose para auxiliar estudantes de patologia e patologistas no diagnóstico da doença. Para isso, foram selecionados 70 casos da forma neurológica da cinomose confirmada pelo achado dos corpúsculos de inclusão característicos no SNC em cães necropsiados no LPV-UFSM. Para determinar a prevalência das lesões, diversas regiões anatômicas do encéfalo e medula espinhal foram selecionadas e sistematicamente examinadas histologicamente em cada caso. As regiões anatômicas mais afetadas, em ordem decrescente, independentemente do tipo de lesão, foram: cerebelo (91,4%), diencéfalo (78,6%), lobo frontal (75,7%), ponte (72,9%) e mesencéfalo (70,0%). Desmielinização foi a lesão mais prevalente, observada em 91,4% dos casos, localizada principalmente no cerebelo (88,6%), ponte (65,7%) e diencéfalo (61,4%). As cinco estruturas anatômicas mais afetadas pela desmielinização foram: teto do quarto ventrículo (68,6%), folhas cerebelares (61,4%), substância medular do cerebelo (61,4%), medula espinhal cervical (46,3%) e tegmento mesencefálico (40,0%). A prevalência das outras lesões foi: encefalite não-supurativa (70,0%), leptomeningite não-supurativa (44,3%), mielite não-supurativa (35,2%), encefalomalacia (31,4%), meningomielite não-supurativa (18,5%), necrose laminar cortical (17,1%), mielomalacia (13,0%), ependimite não-supurativa (7,1%) e plexocoroidite não-supurativa (1,4%). A ocorrência dos corpúsculos de inclusão nas células do SNC foi: astrócitos (82,8%), neurônios (44,3%), gemistócitos (31,4%), células do epêndima (22,8%), células meningoteliais (4,3%) e células do plexo coróide (1,4%).

Canine distemper is one of the most prevalent viral diseases of dogs. Several cases are diagnosed in a daily basis in private practices and veterinary hospitals around the country. Most cases of neurological manifestation of canine distemper are fatal and the diagnosis confirmation by histopathology is often necessary. Canine distemper encephalitis is the main cause of death or reason for euthanasia in dogs necropsied at the Laboratório de Patologia Veterinária (LPV) of the Universidade Federal de Santa Maria…

Advisors/Committee Members: Dominguita Luhers Graça, Alexandre Mazzanti, David Driemeier, Claudete Schmidt, Claudio Severo Lombardo de Barros.

Subjects/Keywords: desmielinização; neuropatologia; cinomose; doenças virais; doenças de cães; MEDICINA VETERINARIA; canine distemper; viral diseases; diseases of dogs; neuropathology; demyelination; encephalitis; encefalite

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Silva, M. C. d. (2009). NEUROPATOLOGIA DA CINOMOSE CANINA. (Thesis). Universidade Federal de Santa Maria. Retrieved from http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=2563

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Silva, Marcia Cristina da. “NEUROPATOLOGIA DA CINOMOSE CANINA.” 2009. Thesis, Universidade Federal de Santa Maria. Accessed March 05, 2021. http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=2563.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Silva, Marcia Cristina da. “NEUROPATOLOGIA DA CINOMOSE CANINA.” 2009. Web. 05 Mar 2021.

Vancouver:

Silva MCd. NEUROPATOLOGIA DA CINOMOSE CANINA. [Internet] [Thesis]. Universidade Federal de Santa Maria; 2009. [cited 2021 Mar 05]. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=2563.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Silva MCd. NEUROPATOLOGIA DA CINOMOSE CANINA. [Thesis]. Universidade Federal de Santa Maria; 2009. Available from: http://coralx.ufsm.br/tede/tde_busca/arquivo.php?codArquivo=2563

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University

18. Axthelm, Michael K. Studies on the entry and persistence of canine distemper virus in the central nervous system.

Degree: PhD, Graduate School, 1985, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

Subjects/Keywords: Health Sciences; Canine distemper virus; Veterinary virology; Virology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Axthelm, M. K. (1985). Studies on the entry and persistence of canine distemper virus in the central nervous system. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

Chicago Manual of Style (16^th Edition):

Axthelm, Michael K. “Studies on the entry and persistence of canine distemper virus in the central nervous system.” 1985. Doctoral Dissertation, The Ohio State University. Accessed March 05, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067.

MLA Handbook (7^th Edition):

Axthelm, Michael K. “Studies on the entry and persistence of canine distemper virus in the central nervous system.” 1985. Web. 05 Mar 2021.

Vancouver:

Axthelm MK. Studies on the entry and persistence of canine distemper virus in the central nervous system. [Internet] [Doctoral dissertation]. The Ohio State University; 1985. [cited 2021 Mar 05]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067.

Council of Science Editors:

Axthelm MK. Studies on the entry and persistence of canine distemper virus in the central nervous system. [Doctoral Dissertation]. The Ohio State University; 1985. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487261553058067

University of Edinburgh

19. Acosta-Jamett, Gerardo. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.

Degree: PhD, 2010, University of Edinburgh

URL: http://hdl.handle.net/1842/4428

► The higher proximity among humans, domestic animals and wildlife favours disease spill-over both from wildlife to domestic animals and vice versa, which is a potential… (more)

▼ The higher proximity among humans, domestic animals and wildlife favours disease spill-over both from wildlife to domestic animals and vice versa, which is a potential risk for the extinction of wildlife populations and could be influencing the emergence and/or re-emergence of zoonotic diseases. The domestic dog (Canis familiaris) is the most abundant and widely distributed carnivore worldwide and is known to be carrying many infectious diseases. Among these diseases, domestic dogs are known to be source of canine distemper virus (CDV), canine parvovirus (CPV) and Echinococcus granulosus to wild carnivores and human being. Populations of domestic dogs inhabiting urban areas can be the source of infection of directly transmitted pathogens, since in these areas a high density of domestic dogs can facilitate the maintenance of these infections to both domestic and wild carnivore populations. In addition, the knowledge of the diseases present in the domestic dog populations in close proximity to wildlife is essential for conservation planning and for control of both zoonotic diseases and diseases of conservation concern. This thesis explores the effect of urbanization on the epidemiology of CDV, CPV, and E granulosus in domestic dogs and wild carnivores of the Coquimbo region of Chile as for example, chilla (L. griseus) and culpeo (L. culpaeus) foxes and assess the risk factors that could be facilitate disease transmission between canid inhabiting urban and rural areas. The first of the chapters containing original data, Chapter 3, describe the demography of dogs in the study area, indicating that urban sites have a greater population and a higher density of domestic dogs, a high growth rate and therefore a high turnover of susceptible than rural areas, which can be of relevance for the differences in diseases transmission patterns between these sites. Chapter 4 describe the degree of interaction between wild and domestic carnivores and its effect on interespecific disease transmission; indicating that in the study area there are many opportunities for domestic/wild carnivores interactions, as for example livestock predation by carnivores, by approaching to peridomestic environments, facilitating in this scenario the transmission of CDV, CPV and also E. granulosus by predating on livestock contaminated with cyst echinococcosis. Chapter 5 indicate that urban areas hold domestic dog populations with higher CDV seroprevalence than rural sites and probably these areas are the source of infection to rural sites. In contrast, a more stable CPV seroprevalence was found between urban and rural areas, indicating that possibly this pathogen follow an endemic state across the study area. Chapter 6 describe the factors for E. granulosus prevalence in domestic dogs, livestock and human being, suggesting that more cases of E. granulosus in livestock and in humans are found in provinces of the Coquimbo region with higher percentage of rural population; however, and unexpectedly, more cases of E. granulosus in domestic dogs were found…

Subjects/Keywords: 636.089; canine distemper virus; canine parvovirus; hydatid disease; domestic dogs; wild carnivores

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Acosta-Jamett, G. (2010). Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/4428

Chicago Manual of Style (16^th Edition):

Acosta-Jamett, Gerardo. “Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.” 2010. Doctoral Dissertation, University of Edinburgh. Accessed March 05, 2021. http://hdl.handle.net/1842/4428.

MLA Handbook (7^th Edition):

Acosta-Jamett, Gerardo. “Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile.” 2010. Web. 05 Mar 2021.

Vancouver:

Acosta-Jamett G. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. [Internet] [Doctoral dissertation]. University of Edinburgh; 2010. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/1842/4428.

Council of Science Editors:

Acosta-Jamett G. Role of domestic dogs in diseases of significance to humans and wildlife health in central Chile. [Doctoral Dissertation]. University of Edinburgh; 2010. Available from: http://hdl.handle.net/1842/4428

20. Chaudhary, Vratika. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.

Degree: MS, Biological Sciences, 2016, Clemson University

URL: https://tigerprints.clemson.edu/all_theses/2352

► Many mammalian carnivore species persist in small, isolated populations as a result of habitat destruction, fragmentation, poaching, and human conflict. Their small numbers, limited genetic… (more)

▼ Many mammalian carnivore species persist in small, isolated populations as a result of habitat destruction, fragmentation, poaching, and human conflict. Their small numbers, limited genetic variability, and increased exposure to domestic animals such as dogs place them at risk of further losses due to infectious diseases. In India, dogs ranging from domestic to feral are associated with villages in and around protected areas, and may serve as reservoirs and vectors of pathogens to the carnivores within. Indiaâ€™s Kanha Tiger Reserve (KTR) is home to a number of threatened and endangered mammalian carnivores including tigers (Panthera tigris), leopards (Panthera pardus), wolves (Canis lupus), and dhole (Cuon alpinus). It also contains hundreds of small villages with associated dog populations, and my goal was to determine whether these dogs pose a disease threat to KTR's wild carnivores. In the summer of 2014 and again in the winter of 2015 I estimated the density of dogs in villages of varying sizes and distances from KTR's core zone, and the exposure of these dogs to four pathogens that could threaten wild carnivores: rabies, canine parvovirus (CPV), canine distemper (CDV), and canine adenovirus (CAV). Dog population densities ranged from 3.7 to 23.7/km2 (14 to 45 dogs/village), and showed no systematic variation with village area or human population size. These dog populations grew in all villages between the summer of 2014 and winter of 2015, primarily through reproduction. No dog tested positive for rabies but I found high levels of seroprevalence to the other three pathogens: CPV (83.6% in summer 2014, 68.4% in winter 2015), CDV (50.7% in summer 2014, 30.4% in winter 2015) and CAV (41.8% in summer 2014, 30.9% in winter 2015). The declines in seroprevalence between summer and winter were primarily due to births in the population, of animals not exposed to the viruses. I opportunistically documented interactions between the dogs and wild carnivores that might allow disease transmission. I measured these interactions as the presence of wild carnivores in surveyed villages. In this study I document the existence of a large population of unvaccinated dogs in and around KTR, with high levels of seroprevalence to pathogens with broad host ranges. These dogs also have frequent contact with wild carnivores. I conclude that these dogs pose a high risk of disease spillover to wild carnivores in the region. I also tested for CPV and CDV in wild carnivore samples obtained from the KTR Forest Department from 2010 to 2015. While one tiger blood sample was seropositive for CPV antibodies, the reverse transcriptase polymerase chain reaction found no evidence of CPV in tissue samples from five tigers, one leopard and one palm civet (Paradoxurus hermaphroditus), and no CPV or CDV in the three blood samples of tigers. Despite these results, I argue for continued surveillance in KTR, given the ubiquity of village dogs in the area with high seroprevalence of CDV and CPV and the contact between dogs and… Advisors/Committee Members: Dr. David W. Tonkyn, Committee Chair, Dr. Charles Rice, Dr. A. B. Shrivastav.

Subjects/Keywords: Canine adeno virus; Canine distemper virus; Canine parvovirus; Infectious disease; Leopard; Tiger

…Helden & Millar, 2014), canine distemper virus (CDV) in Amur tigers (… …carried by dogs and affect many carnivore species worldwide are the rabies virus, canine… …parvovirus (CPV), CDV (Pedersen et al., 2007), and canine adeno virus (CAV… …against CPV, CDV and CAV with BioGal’s Immunocomb canine vaccichek solid phase immunoassay kit…

7 more images…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chaudhary, V. (2016). Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/2352

Chicago Manual of Style (16^th Edition):

Chaudhary, Vratika. “Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.” 2016. Masters Thesis, Clemson University. Accessed March 05, 2021. https://tigerprints.clemson.edu/all_theses/2352.

MLA Handbook (7^th Edition):

Chaudhary, Vratika. “Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India.” 2016. Web. 05 Mar 2021.

Vancouver:

Chaudhary V. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. [Internet] [Masters thesis]. Clemson University; 2016. [cited 2021 Mar 05]. Available from: https://tigerprints.clemson.edu/all_theses/2352.

Council of Science Editors:

Chaudhary V. Threats of Disease Spillover from Domestic Dogs to Wild Carnivores in the Kanha Tiger Reserve, India. [Masters Thesis]. Clemson University; 2016. Available from: https://tigerprints.clemson.edu/all_theses/2352

Universidade do Rio Grande do Sul

21. Sonne, Luciana. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.

Degree: 2008, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/13843

►

A cinomose canina é uma doença viral e afeta principalmente os sistemas respiratório, gastrintestinal e nervoso. O presente trabalho analisou 54 cães com cinomose de… (more)

▼

A cinomose canina é uma doença viral e afeta principalmente os sistemas respiratório, gastrintestinal e nervoso. O presente trabalho analisou 54 cães com cinomose de um total de 760 cães necropsiados no período de julho de 2006 a outubro de 2007. As lesões macroscópicas observadas eram caracterizadas por secreção ocular e nasal mucopurulentas, hiperqueratose dos coxins digitais, pulmões de coloração avermelhada e não colabados, atrofia do timo, conteúdo intestinal diarréico e evidenciação das placas de Peyer. Os achados microscópicos caracterizavam-se principalmente por pneumonia intersticial, rarefação linfóide, desmielinização da substância branca, manguitos perivasculares e corpúsculos de inclusão viral na mucosa do estômago, epitélios da bexiga, brônquios e bronquíolos, pelve renal, coxins digitais, pálpebra e orelha, no sistema nervoso central (principalmente em astrócitos) e em células mononucleares dos linfonodos, baço e tonsilas. O teste de imunoistoquímica foi positivo em 94,4% dos casos analisados. Os tecidos foram marcados pela técnica imunoistoquímica utilizando o anticorpo monoclonal anti-cinomose canina (VMRD) na diluição de 1:400. O coxim digital se apresentou como o órgão com o maior número de casos marcados positivamente (67,4%), seguido pelo estômago com 62,7%. A utilização da imunoistoquímica auxiliou na identificação do antígeno viral em diferentes tecidos e foi importante como diagnóstico complementar da cinomose canina.

Canine distemper is a viral disease that affects mainly, respiratory, gastrointestinal and nervous system. The present study analyzed 54 dogs with canine distemper from total of 760 necropsies done in dogs between July 2006 to October 2007. The macroscopic lesion were characterized by mucopurulent oculonasal discharge, hyperkeratosis of footpads, red and not collapsed lungs, thymic atrophy, watery intestinal, hyperemia and Peyer’s patches enlarged. The microscopic findings were characterized by interstitial pneumonia, lymphoid depletion, white matter demylization, perivascular cuffs and viral inclusion bodies located in stomach mucosa, bladder, bronchial, renal pelvis, footpads, eyelid, skin of the ear epithelium, central nervosus system (mainly in astrocytes) and mononuclear infiltrates in lymph nodes, spleen, and tonsils. The immunohistochemistry test was positive in 94,4% of analyzed cases. Tissues were strained by an immunohistochemical procedure with mouse monoclonal anti-cinomose (VMRD) diluted 1:400. The footpads was the best tissue with majority of positive marked cases (67,4%), followed by stomach with 62,7%. This observation suggests that the immunohistochemistry technique aided to identify distemper virus antigens in different tissue making it an important test for complementary diagnostic of canine distemper.

Advisors/Committee Members: Carissimi, Andre Silva.

Subjects/Keywords: Patologia veterinaria : Caes; Canine distemper; Dogs; Vírus da cinomose canina; Imunohistoquimica : Virus; Immunohistochemistry

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sonne, L. (2008). Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/13843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sonne, Luciana. “Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.” 2008. Thesis, Universidade do Rio Grande do Sul. Accessed March 05, 2021. http://hdl.handle.net/10183/13843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sonne, Luciana. “Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina.” 2008. Web. 05 Mar 2021.

Vancouver:

Sonne L. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2008. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10183/13843.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sonne L. Achados patológicos e imunoistoquímicos de cães infectados pelo vírus da cinomose canina. [Thesis]. Universidade do Rio Grande do Sul; 2008. Available from: http://hdl.handle.net/10183/13843

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Universidade do Rio Grande do Sul

22. Budaszewski, Renata da Fontoura. Estudos sobre vacinologia e evolução do vírus da cinomose canina.

Degree: 2017, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/163434

►

O vírus da cinomose canina (CDV) é um importante patógeno de cães domésticos e carnívoros selvagens. A infecção pelo CDV é relevante a nível mundial… (more)

▼

O vírus da cinomose canina (CDV) é um importante patógeno de cães domésticos e carnívoros selvagens. A infecção pelo CDV é relevante a nível mundial e está associada com alta morbidade e mortalidade. Em diversos países a cinomose é considerada controlada pelo uso de vacinas, no entanto, no Brasil ainda é endêmica, principalmente devido ao grande número de animais não domiciliados. Além disso, surtos em cães e várias espécies de animais silvestres ocorrem com frequência, dizimando populações ameaçadas. As vacinas vivas atenuadas são seguras para cães, mas seu uso não é aconselhado em espécies altamente suscetíveis à infecção pelo CDV. Também os relatos de surtos de cinomose em cães supostamente vacinados levantam a hipótese de que as vacinas disponíveis no mercado podem não ser eficientes frente a algumas cepas de campo. Com o objetivo de gerar dados acerca dos mecanismos de evolução do CDV e desenvolver e testar a eficácia de uma vacina bivalente inativada contra o vírus da raiva (RABV) e CDV a presente tese será apresentada na forma de dois artigos científicos. Ainda, um artigo de revisão sobre os modelos animais utilizados para obtenção de informações sobre o vírus do sarampo utilizando a infecção de CDV em furões e cães foi publicada e será apresentada na presente tese. No primeiro artigo, foi analisada a ocorrência de recombinação homóloga em genomas de CDV e detectou-se oito possíveis vírus recombinantes, incluindo um evento de recombinação entre uma cepa de campo e uma cepa vacinal atenuada, sugerindo que o uso de vacinação com vírus vivo atenuado pode influenciar a evolução do CDV. No segundo trabalho, uma vacina recombinante bivalente inativada baseada em RABV expressando as glicoproteínas do envelope do CDV, hemaglutinina e proteína de fusão, mostrou-se eficiente na proteção contra infecção por CDV em furões quando utilizado um protocolo prime/boost. Finalmente, foi publicada uma revisão de literatura sobre os modelos animais utilizados para obtenção de informações sobre a patogênese do vírus do sarampo utilizando a infecção com o vírus da cinomose.

Canine distemper virus (CDV) is an important pathogen of domestic dogs and wild carnivores. CDV infection is globally relevant and it is associated with high morbidity and mortality. In several countries, distemper is considered controlled by vaccination, however, in Brazil it is still endemic, mainly due to the large number of non-domiciliated animals. In addition, outbreaks in dogs and various species of wild animals occur frequently, decimating threatened populations. Live attenuated vaccines are safe for dogs, but their use is not advised in species that are highly susceptible to CDV infection. Also, reports of canine distemper in supposedly vaccinated dogs raise the hypothesis that commercially available vaccines may not be effective against some wild type strains. In order to investigate the mechanisms of CDV evolution and to develop and assess the efficacy of an inactivated bivalent vaccine against rabies virus and CDV, this thesis will be presented in…

Advisors/Committee Members: Canal, Cláudio Wageck.

Subjects/Keywords: Virologia veterinaria; Canine distemper virus; Vírus da cinomose canina; Homologous recombination; Virus da raiva; Vaccine; Rabies virus; Recombinação homóloga; Vacinas; Animal models; Modelos animais

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Budaszewski, R. d. F. (2017). Estudos sobre vacinologia e evolução do vírus da cinomose canina. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/163434

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Budaszewski, Renata da Fontoura. “Estudos sobre vacinologia e evolução do vírus da cinomose canina.” 2017. Thesis, Universidade do Rio Grande do Sul. Accessed March 05, 2021. http://hdl.handle.net/10183/163434.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Budaszewski, Renata da Fontoura. “Estudos sobre vacinologia e evolução do vírus da cinomose canina.” 2017. Web. 05 Mar 2021.

Vancouver:

Budaszewski RdF. Estudos sobre vacinologia e evolução do vírus da cinomose canina. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2017. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10183/163434.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Budaszewski RdF. Estudos sobre vacinologia e evolução do vírus da cinomose canina. [Thesis]. Universidade do Rio Grande do Sul; 2017. Available from: http://hdl.handle.net/10183/163434

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

23. Köhnke, Rebecca. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.

Degree: 2018, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-857

► Hundestaupevirus als möglicher Vektor für SIV-Antigene – Etablierung rekombinanter Vektoren mit und ohne SIVgag-Insert und Evaluierung dieser Vektoren auf klinische Sicherheit und Immunogenität im Frettchenmodell… (more)

▼ Hundestaupevirus als möglicher Vektor für SIV-Antigene – Etablierung rekombinanter Vektoren mit und ohne SIVgag-Insert und Evaluierung dieser Vektoren auf klinische Sicherheit und Immunogenität im Frettchenmodell Das Humane Immunodefizienz-Virus (HIV) und das durch die Infektion letztendlich verursachte erworbene Immundefizienzsyndrom (AIDS) werden oft als eine moderne Plage der Menschheit bezeichnet. Aufgrund der besonderen Biologie des HI-Virus kann mit medikamentöser Behandlung derzeit das Virus nicht eliminiert erden. Vorbeugende Maßnahmen haben zwar weltweit die Neuinfektionsrate vermindert, aber es wird davon ausgegangen, dass letztendlich nur ein Impfstoff für ein Ende des Ausbreitens der Epidemie sorgen kann. Um die Pathogenese, Behandlung und Prävention einer HIV-Infektion wissenschaftlich zu untersuchen, wird häufig auf das nicht humanpathogene Simian Immunodeficiency Virus (SIV) als Modellorganismus zurückgegriffen. Zahlreiche verschiedene Impfstoffansätze sind in der Entwicklung, wobei die Verwendung viraler Vektoren sich über die letzten Jahre als erfolgversprechend erwiesen hat. Speziell die Applikation solcher Vektoren über die Schleimhäute hat wiederholt zu der verstärkten Ausbildung mukosaler Immunantworten geführt und ist deshalb von Interesse. Ein geeigneter Vektor verfügt über ähnliche Charakteristiken wie das pathogene Virus, gegen das geimpft werden soll, vor allem in Bezug auf Zelltropismus und Ort der Virusreplikation im Körper. Dadurch werden die im Vektor inkorporierten Fremdantigene direkt an die während einer natürlichen Infektion relevanten anatomischen Strukturen geführt. Morbilliviren infizieren ihre natürlichen Wirte über die Schleimhäute. Daraufhin infiziert das Virus bevorzugt T-Zellen, vor allem im gastrointestinalen lymphatischen System, und verursacht so eine Immunsuppression. Im Rahmen dieser Arbeit wurde ein attenuiertes Hundestaupevirus als Vektor für SIV-Antigene evaluiert. Das Hundestaupevirus ist in vitro fähig Primatenzellen zu infizieren, aber nicht humanpathogen. Das Virus wurde als rekombinantes Virus aus Zellkultur isoliert und die Erbinformation für das SIV gag Protein in den Vektor integriert. Gag ist ein hoch immunogenes, wichtige virales Strukturprotein. Replikationsfähigkeit und Infektiosität der rekombinanten Vektoren in vitro sowie Präsenz der Gag-Sequenz wurden überprüft. Die rekombinanten Vektoren wurden dann auf intranasalem Wege an staupe-empfängliche Frettchen verabreicht. Der klinische Zustand der Frettchen und das Vorhandensein von Staupesymptomen wurden überprüft. Wiederholt wurden Blut- und Gewebeproben auf Virusgehalt und Hinweise auf Immunreaktionen untersucht. Das rekombinante Staupevirus mit SIV Gag-Insert hat sich in dieser Studie in einer hochempfindlichen Spezies als klinisch unbedenklich, aber dennoch replikationsfähig erwiesen. Blut- und Gewebeproben weisen Anzeichen humoraler und zellulärer Immunreaktionen sowohl auf den Vektor selbst als auch auf das Insert auf. Advisors/Committee Members: female (gender), Gruber, Achim (firstReferee), Hartmann, Susanne (furtherReferee), Osterrieder, Klaus (furtherReferee).

Subjects/Keywords: Ferrets; Animal Models; Canine Distemper Virus; Genetic Vectors; Gag Protein; Epidemiology; Simian Immunodeficiency Virus(MeSH); 600 Technology, Medicine, Applied sciences::630 Agriculture, Veterinary medicine::630 Agriculture, Veterinary medicine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Köhnke, R. (2018). Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-857

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Köhnke, Rebecca. “Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.” 2018. Thesis, Freie Universität Berlin. Accessed March 05, 2021. http://dx.doi.org/10.17169/refubium-857.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Köhnke, Rebecca. “Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens.” 2018. Web. 05 Mar 2021.

Vancouver:

Köhnke R. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. [Internet] [Thesis]. Freie Universität Berlin; 2018. [cited 2021 Mar 05]. Available from: http://dx.doi.org/10.17169/refubium-857.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Köhnke R. Recombinant Canine Distemper Virus as a Possible Vector for the Delivery of Simian Immunodeficiency Virus Antigens. [Thesis]. Freie Universität Berlin; 2018. Available from: http://dx.doi.org/10.17169/refubium-857

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

24. Rentería-Solís, Zaida Melina. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.

Degree: 2017, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-5943

► Seit seiner ersten, 1934 erfolgten, Einbürgerung ist der Nordamerikanische Waschbär (Proyon lotor) eine invasive Tierart in Deutschland. Waschbären sind in Deutschland weit verbreitet, können aber… (more)

▼ Seit seiner ersten, 1934 erfolgten, Einbürgerung ist der Nordamerikanische Waschbär (Proyon lotor) eine invasive Tierart in Deutschland. Waschbären sind in Deutschland weit verbreitet, können aber in zwei Hauptpopulationen differenziert werden: Eine im Zentrum (Hessen), eine andere im nordöstlichen Landesteil (Mecklenburg-Vorpommern, Brandenburg). In Nordamerika gilt der Waschbär als bekannter Überträger von Infektionserregern wie Tollwut, Staupe oder dem zoonotischen Nematoden Baylisascaris procyonis. Aber trotz ihrer 70 Jahre währenden, erfolgreichen Einbürgerung gibt es wenig Kenntnis zu Infektionskrankheiten bei Waschbären in Deutschland. Um zu untersuchen, welche Krankheiten oder Krankheitserreger bei diesen Tieren vorkommen, wurden zwei Teilpopulationen in Nordostdeutschland ausgewählt: eine in einem ländlichen Waldgebiet (Müritz Nationalpark (MNP), Mecklenburg-Vorpommern), ein urbane im Großraum Berlin. Insgesamt wurden 240 Verkehrsopfer, jagdlich erlegte oder eingeschläferte Waschbären untersucht: 100 aus dem MNP (2007 bis 2011) und 140 aus Berlin (2011-2013). Tierkörpersektionen, histologische, mikrobiologische und molekularbiologische Untersuchungen von ausgewählten Erregern wurden mit diesen Tieren durchgeführt. Die Ergebnisse sind in vier wissenschaftlichen Artikeln veröffentlicht: Artikel I: In vorangegangenen Studien histologisch entdeckte Parasitenzysten im Zungengewebe von Waschbären wurden untersucht und ihre Artzugehörigkeit identifiziert. Mesozerkarien konnten aus neun Tieren vom MNP und einem Tier aus Berlin isoliert und mittels PCR als Alaria alata in identifiziert werden. In histologischen Untersuchungen wurden A. alata Mesozerkarien nur in Zungengewebe detektiert, jedoch nicht in anderen Organen. Das deutet darauf hin, dass Waschbären für diesen Trematoden als paratenische Wirte auftreten. Die höhere Anzahl positiver A. alata Fälle im MNP im Vergleich zu Berlin läßt sich durch Unterschiede in der Nahrungszusammensetzung erklären, da den Waschbären im MNP häufiger Zwischenwirte von A. alata, wie Amphibien, zur Verfügung stehen als den urbanen Waschbären. Es konnte hier gezeigt werden, dass eine neueingebürgerte Art wie der Waschbär das Wirtsspektrum endemischer Parasiten erweitern kann. Artikel II: Der zweite Artikel aus diesem Projekt beschreibt Sarcoptesräude in urbanen Waschbären mit drei Fällen aus Berlin und zwei Fällen aus Kassel. Makroskopische Hautläsionen, histo-pathologische Befunde und die Morphologie der Milben werden beschrieben. Um den möglichen Ursprung der Infektionen zu finden, wurden neun Mikrosatellitenmarker für die Genotypisierung der von Waschbären isolierten Milben verwendet, um sie mit S. scabiei von Füchsen, Wildschweinen und Gämsen zu vergleichen. Die Milben der Waschbären lagen in einem Cluster mit S. scabiei von Füchsen, was für einem Infektionsursprung aus Füchsen spricht. Diese Ergebnisse deuten auf eine zwischenartliche Übertragung von S. scabiei zwischen urbanen Füchsen und Waschbären hin. Artikel III: Der erste große Staupeausbruch von Waschbären in Deutschland… Advisors/Committee Members: w (gender), Univ.-Prof. Dr. Alex Greenwood (firstReferee), PD Dr. Kerstin Müller (furtherReferee), Prof. Dr. Katharina Riehn (furtherReferee).

Subjects/Keywords: Procyon lotor; Alaria alata; Sarcoptes scabiei; animal parasitic nematodes; Canine distemper virus; Mecklenburg-Pomerania; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Rentería-Solís, Z. M. (2017). Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-5943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Rentería-Solís, Zaida Melina. “Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.” 2017. Thesis, Freie Universität Berlin. Accessed March 05, 2021. http://dx.doi.org/10.17169/refubium-5943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Rentería-Solís, Zaida Melina. “Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland.” 2017. Web. 05 Mar 2021.

Vancouver:

Rentería-Solís ZM. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. [Internet] [Thesis]. Freie Universität Berlin; 2017. [cited 2021 Mar 05]. Available from: http://dx.doi.org/10.17169/refubium-5943.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rentería-Solís ZM. Vorkommenden Krankheitsfälle bei frei lebenden Waschbären (Procyon lotor) aus ruralen und urbanen Populationen in Nordostdeutschland. [Thesis]. Freie Universität Berlin; 2017. Available from: http://dx.doi.org/10.17169/refubium-5943

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

25. Woma, Timothy Yusufu. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.

Degree: Veterinary Tropical Diseases, 2008, University of Pretoria

URL: http://hdl.handle.net/2263/26280

► Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains… (more)

▼ Studies comparing canine distemper virus (CDV) strains from Africa with that of previously described lineages have been hampered due to a lack of field strains for in vitro experiments. There are no reports of CDV isolations in southern Africa, and although CDV is said to have geographically distinct lineages, molecular information of African strains has not yet been documented. Clinical specimens consisting of whole blood, spleen, lungs, brain and cerebrospinal fluid from dogs with clinical signs suggestive of distemper were obtained from private veterinary practices and diagnostic laboratories in Gauteng province, South Africa. One hundred and sixty two specimens from 124 dogs were inoculated into Vero cells expressing canine signalling lymphocyte activation molecule (Vero.DogSLAM). Cytopathic effects (CPE) in the form of syncytia formation and cell necrosis were observed in 33 (20.4%) specimens within 24 hours of inoculation and the presence of CDV was confirmed with the aid of the direct fluorescent antibody test and electronmicroscopy (EM). Viruses isolated in cell cultures were subjected to reverse transcription – polymerase chain reaction (RT-PCR), and the complete H gene was sequenced and phylogenetically analysed with other strains from GenBank. The animals all displayed the catarrhal, systemic, or nervous signs of the disease. Four of the dogs positive for CDV by viral isolation had a history of prior vaccinations to canine distemper. Seventy three percent of all positive dogs were less than 12 months old. There was no breed or sex predisposition to CDV infection in domestic dogs. Phylogenetic comparisons of the complete H gene of CDV isolates from different parts of the world (available in GenBank) with wild-type South African isolates revealed nine clades. All South African isolates form a separate African clade of their own and thus are clearly separated from the American, European, Asian, Arctic and vaccine virus clades. It is likely that only the ‘African lineage’ of CDV may be circulating in South Africa currently, and the viruses isolated from dogs vaccinated against CDV are not the result of reversion to virulence of vaccine strains, but infection with wild-type strains. Copyright Advisors/Committee Members: Van Vuuren, Moritz (advisor).

Subjects/Keywords: Canine distemper virus; Domestic dogs; South Africa; UCTD; Dogs – Diseases

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Woma, T. Y. (2008). The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/26280

Chicago Manual of Style (16^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.” 2008. Masters Thesis, University of Pretoria. Accessed March 05, 2021. http://hdl.handle.net/2263/26280.

MLA Handbook (7^th Edition):

Woma, Timothy Yusufu. “The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa.” 2008. Web. 05 Mar 2021.

Vancouver:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. [Internet] [Masters thesis]. University of Pretoria; 2008. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/2263/26280.

Council of Science Editors:

Woma TY. The isolation and genetic characterization of canine distemper viruses from domestic dogs (Canis familiaris) in South Africa. [Masters Thesis]. University of Pretoria; 2008. Available from: http://hdl.handle.net/2263/26280

Universidade do Rio Grande do Sul

26. Hartmann, Tamahine Larronda Schmidt. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.

Degree: 2006, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/8197

►

O vírus da cinomose canina (CDV) e o vírus parainfluenza canino (CPIV) afetam uma ampla variedade de hospedeiros e encontram-se distribuídos mundialmente. O CDV é… (more)

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O vírus da cinomose canina (CDV) e o vírus parainfluenza canino (CPIV) afetam uma ampla variedade de hospedeiros e encontram-se distribuídos mundialmente. O CDV é considerado um dos mais importantes agentes infecciosos dentro das populações caninas. Este vírus é o agente causal da cinomose, uma doença potencialmente letal em membros das famílias Canidae, Mustelidae e Procionidae, sendo recentemente detectado como causa de morbidade e mortalidade em carnívoros aquáticos e grandes felinos. O CPIV, por sua vez, é altamente contagioso entre cães, podendo infectar roedores e gatos em infecções experimentais. Geralmente, o CPIV produz uma traqueobronquite aguda auto-limitante, porém pode atuar sinergicamente com outros agentes infecciosos, como o CDV, causando sinais clínicos mais graves. Como em nosso meio são escassas as informações sobre estes vírus, o presente estudo visou aprofundar os conhecimentos sobre a prevalência de CDV e CPIV em cães e felinos silvestres mantidos em cativeiro. Para tanto, soros destes animais foram testados em busca de anticorpos neutralizantes contra amostras padrão do CDV (Rockborn e Snyder Hill) e do CPIV (V660). Inicialmente, foram testados soros de 173 cães de rua mantidos em canis municipais em Novo Hamburgo e Porto Alegre, RS. A prevalência de anticorpos neutralizantes anti-CDV frente às amostras de vírus da cinomose Rockborn e Snyder Hill, foi de 9,3 % e 4,1 %, respectivamente. Somente dois cães apresentaram títulos de anticorpos considerados protetores contra CDV Rockborn (igual ou maior que 100) e nenhum soro apresentou título de anticorpos neutralizantes considerado protetor para a amostra Snyder Hill (igual ou maior que 100). Contra a amostra de parainfluenza canino V660, a prevalência de anticorpos neutralizantes encontrada foi de 51,4 %. Conclui-se, portanto, que a população de cães de rua amostrada apresenta poucos indícios de contato prévio com CDV, sugerindo grande susceptibilidade à cinomose. Por outro lado, o CPIV parece circular amplamente nesta população. Na segunda parte do presente estudo, como no Brasil não existem relatos sobre CDV e CPIV em felinos silvestres, buscou-se verificar a possibilidade da ocorrência dessas infecções em felinos silvestres brasileiros. Para tanto, foram testados soros de 84 felinos silvestres de seis diferentes espécies nativas do Brasil (Leopardus tigrinus, Puma concolor, Leopardus wiedii, Herpailurus yaguarondi, Panthera onca), todos mantidos em cativeiro em criatórios de distintas regiões do País. Todos os felinos amostrados apresentaram-se soronegativos frente às amostras de CDV e CPIV utilizadas. Estes resultados indicam que CDV e CPIV parecem não circular nas populações de felinos silvestres amostradas.

Canine distemper virus (CDV) and canine parainfluenza virus (CPIV) infect a great variety of hosts ranges and are distributed worldwide. CDV is one of the most important infectious agents in dogs. This virus may cause potentially lethal disease among members of the Canidae, Mustelidae and Procionidae families. It has also caused…

Advisors/Committee Members: Roehe, Paulo Michel.

Subjects/Keywords: Canine distemper virus; Virologia veterinaria; Canine parainfluenza virus; Cinomose; Dogs; Imunologia veterinaria : Caes; Wild felids; Imunologia : Anticorpos; Sero neutralization; Prevalence

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hartmann, T. L. S. (2006). Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/8197

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hartmann, Tamahine Larronda Schmidt. “Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.” 2006. Thesis, Universidade do Rio Grande do Sul. Accessed March 05, 2021. http://hdl.handle.net/10183/8197.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hartmann, Tamahine Larronda Schmidt. “Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro.” 2006. Web. 05 Mar 2021.

Vancouver:

Hartmann TLS. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2006. [cited 2021 Mar 05]. Available from: http://hdl.handle.net/10183/8197.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hartmann TLS. Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro. [Thesis]. Universidade do Rio Grande do Sul; 2006. Available from: http://hdl.handle.net/10183/8197

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. Fábio Juliano Negrão. Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina.

Degree: 2004, Universidade Estadual de Londrina

URL: http://www.bibliotecadigital.uel.br/document/?code=vtls000098970

►

Urine and leucocytes from 56 dogs with canine distemper clinical diagnosis were evaluated by use in reverse transcription-polymerase chain reaction (RT-PCR) to canine distemper virus… (more)

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Urine and leucocytes from 56 dogs with canine distemper clinical diagnosis were evaluated by use in reverse transcription-polymerase chain reaction (RT-PCR) to canine distemper virus (CDV) hemagglutinin gene. In accordance with clinical signs the dogs was disposed in tree groups (A/systemic=17; B/neurological=8; C/systemic and neurological=31) the partial amplification from 721 base pare was possible 45 of 56 dogs. In 34 of 56 dogs the CDV was detected such in urine as in leucocytes. In 11 of 45 dogs only one biological sample was positive (urine=1 dog; leucocytes=10 dogs). It is advisable at least two biological sample to detect the CDV. The variability of canine distemper sings and the material choice may be to generate false-negative results principally en dogs with only systemic clinical sings (A group) where in 7 of 17 dogs was negative when compared with 1/8 B group and 3/31 C group, it is advisable at least two biological sample to detect the CDV. In other experiment 27 dogs positive and 5 negative by RT-PCR to CDV nucleoprotein gene were disposed in four groups in accordance with clinical sings (systemic=10 dogs; neurological=8 dogs; systemic and neurological= 9; control=5). To restriction fragment length polymorphism assay (RFLP) the enzymes Hinf I and Rsa I were selected to determine the RFLP pattern from 721 base pare (bp) fragment of haemagglutinin gene was amplified by using directly biological sample and the laboratory CDV strain Onderstepoor, Rockborn and Snyder Hill. Everyone PCR products after digestion with Hinf I were cut in two seeing fragment of 320 and 230 bp. The wild-type CDV PCR products later than digestion with Rsa I were cut into two seeing fragment around 360 and 230 bp that differ from the laboratory CDV strain. The Onderstepoort PCR product after than digest with Rsa I was cut in 363 and 327 bp. The RFLP pattern with Rsa I from Snyder Hill and Rockborn were the same two fragments with 363 and 358 bp. The Rockborn strain dont have the genome in public database, but the computational analysis using public nucleotide sequence database and this study show the same RFLP pattern for Onderstepoort and Snyder Hill. The PCR and RFLP products were detected by electrophoresis in 2% agarose gels with ethidium bromide staining and the little fragments dont be seeing. The molecular relationships showed in RFLP analysis suggest that wild-type current in north Paraná are unlike from laboratory CDV strains, and this different RFLP pattern may be characterize molecular distinction.

Urina e leucócitos de 56 cães com diagnóstico clínico de cinomose foram avaliados comparativamente pela técnica de Transcrição Reversa seguida de Reação em Cadeia pela Polimerase (RT-PCR) para o gene da hemaglutinina (Gene H) do vírus da cinomose canina, urina e leucócitos de 56 cães com diagnóstico clínico de cinomose. De acordo com a predominância dos sinais clínicos os cães foram distribuídos em três grupos (17=sistêmicos; 8=neurológicos e 31=sistêmicos e neurológicos). A amplificação do segmento de 721 pares de base…

Advisors/Committee Members: Amari Alcindo Alfieri ., Alice Fernandes.Alfieri.

Subjects/Keywords: Cinomose canina; Virologia veterinária; Sanidade animal; Biologia Molecular; Hemaglutinina; Canine distemper; Veterinary virology; Hemagglutinin

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Negrão, F. J. (2004). Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina. (Thesis). Universidade Estadual de Londrina. Retrieved from http://www.bibliotecadigital.uel.br/document/?code=vtls000098970

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Negrão, Fábio Juliano. “Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina.” 2004. Thesis, Universidade Estadual de Londrina. Accessed March 05, 2021. http://www.bibliotecadigital.uel.br/document/?code=vtls000098970.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Negrão, Fábio Juliano. “Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina.” 2004. Web. 05 Mar 2021.

Vancouver:

Negrão FJ. Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina. [Internet] [Thesis]. Universidade Estadual de Londrina; 2004. [cited 2021 Mar 05]. Available from: http://www.bibliotecadigital.uel.br/document/?code=vtls000098970.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Negrão FJ. Avaliação molecular parcial do gene da hemaglutinina do vírus da cinomose canina. [Thesis]. Universidade Estadual de Londrina; 2004. Available from: http://www.bibliotecadigital.uel.br/document/?code=vtls000098970

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Freie Universität Berlin

28. Günther-Weigl, Astrid. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.

Degree: 2009, Freie Universität Berlin

URL: http://dx.doi.org/10.17169/refubium-11518

► Staupe, eine hochinfektiöse, systemische Viruserkrankung der Hunde und anderer Karnivoren, wird als die bedrohlichste Infektionskrankheit der Marderartigen betrachtet. In dieser Arbeit wurde die Sicherheit und… (more)

▼ Staupe, eine hochinfektiöse, systemische Viruserkrankung der Hunde und anderer Karnivoren, wird als die bedrohlichste Infektionskrankheit der Marderartigen betrachtet. In dieser Arbeit wurde die Sicherheit und Wirksamkeit der in Europa verfügbaren Staupeimpfstoffe bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und ansatzweise bei Nordamerikanischen Fischottern (Lontra canadensis) ermittelt. Zwei Methoden zur Antikörperbestimmung wurden verglichen. Der Referenzstandard zum Antikörpernachweis gegen Morbilliviren ist der Neutralisationstest (NT). Dieser ist zeitaufwendig und teuer. Ein kostengünstiger und schnell durchführbarer ELISA wäre sehr hilfreich. Siebzig Otter, aus 19 verschiedenen Zoos und Tierparks in Deutschland und den Niederlanden, beiderlei Geschlechts und im Alter zwischen 8 Wochen und 17 Jahren wurden geimpft. Zwei Studien wurden durchgeführt. In Studie 1 wurden bisher ungeimpfte Europäische Fischotter (n=27), Asiatische Kurzkrallenotter (n=28) und Nordamerikanische Fischotter (n=4) entweder mit inaktiviertem Staupeimpfstoff, mit CDV-ISCOM Impfstoff oder mit einem von drei verschiedenen Staupe Lebendimpfstoffen geimpft. In Studie 2 wurden die Antikörper (AK) Titer Europäischer Fischotter (n=11), die bisher regelmäßig gegen Staupe geimpft wurden, vor und nach einer Booster Impfung bestimmt. Folgende Ergebnisse wurden ermittelt: Bei keinem der Otter wurden klinische Symptome einer Staupe Erkrankung beobachtet. Die Immunantwort auf inaktivierten Staupeimpfstoff war schwach. CDV-ISCOM Impfstoff führte bei allen Tieren zu einer humoralen Immunantwort, hohe AK- Titer wurden jedoch nur im ELISA gemessen. Die Immunantwort auf Lebendimpfoff zeigte bei Europäischen Fischottern eine Abhängigkeit vom Impfstamm. Alter, Geschlecht, Tierart und Gewicht hatten keinen Einfluss auf die Immunantwort nach Impfung mit Staupe Lebendimpfstoff. Die drei Impfstofftypen (inaktiviert, ISCOM, lebend) zeigten einen signifikanten Unterschied in der Wirksamkeit, wobei Staupe Lebendimpfstoffe vom Onderstepoort Typ sich als am wirksamsten erwiesen. Zwischen Europäischen Fischottern und Asiatischen Kurzkrallenottern gab es keinen Unterschied in der Höhe der neutralisierenden AK-Titer nach zwei Impfdosen. Der Zusammenhang zwischen den zwei Nachweismethoden war nicht sehr stark. Booster Impfung bei Europäischen Fischottern mit Lebendimpfstoff (Onderstepoort Typ) induzierte einen signifikanten Anstieg der neutralisierenden AK, die bis Tag 365 nach Impfung auf einem angemessenen Level blieben. Die Ergebnisse führten zu folgenden Schlussfolgerungen: Der Einsatz der formalin-inaktivierten Staupe Vakzine mit Al(OH)3 als Adjuvant ist bei den getesteten Fischotterarten nicht sinnvoll. Staupe Lebendimpfstoffe vom Onderstepoort Typ sind wirksam bei Europäischen Fischottern und Asiatischen Kurzkrallenottern und scheinen bei diesen Arten sicher zu sein. Der experimentelle CDV-ISCOM Impfstoff ist sicher und wahrscheinlich eine wirksame Alternative. Der in dieser Studie eingesetzte ELISA ist einsetzbar für… Advisors/Committee Members: [email protected] (contact), w (gender), Univ.-Prof. Dr. Heribert Hofer (firstReferee), Prof. Dr. Klaus Eulenberger, (furtherReferee), Univ.-Prof. Klaus Osterrieder (furtherReferee).

Subjects/Keywords: Aonyx cinereus; canine distemper virus; immune response; Lontra canadensis; Lutra lutra; otters; vaccination; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Günther-Weigl, A. (2009). Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-11518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Günther-Weigl, Astrid. “Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.” 2009. Thesis, Freie Universität Berlin. Accessed March 05, 2021. http://dx.doi.org/10.17169/refubium-11518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Günther-Weigl, Astrid. “Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen.” 2009. Web. 05 Mar 2021.

Vancouver:

Günther-Weigl A. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. [Internet] [Thesis]. Freie Universität Berlin; 2009. [cited 2021 Mar 05]. Available from: http://dx.doi.org/10.17169/refubium-11518.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Günther-Weigl A. Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen. [Thesis]. Freie Universität Berlin; 2009. Available from: http://dx.doi.org/10.17169/refubium-11518

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Minnesota

29. Craft, Meggan E. Predicting disease dynamics in African lion populations.

Degree: Ecology, Evolution and Behavior, 2008, University of Minnesota

URL: http://purl.umn.edu/46993

► In 1994, one-third of Serengeti lions died from canine distemper virus (CDV). I estimated the epidemiological network structure of the Serengeti lion population using long-term… (more)

▼ In 1994, one-third of Serengeti lions died from canine distemper virus (CDV). I estimated the epidemiological network structure of the Serengeti lion population using long-term data. I found that the lion population is a mix of local pride-to-pride contacts (driven by territory adjacencies) and transient nomad-to-pride contacts (driven by gamma variance process). When canine distemper virus (CDV) was introduced into the network, I found that although nomads are numerous, travel long distances, and are likely candidates to be considered "superconnectors" (connecting distant parts of a network), their impacts on CDV disease dynamics were surprisingly low. Analysis of the data-driven, Levins-type network model demonstrates that the epidemic probably was not propagated solely by within-species transmission but rather involved multiple introductions from other carnivore species, such as jackals and hyenas. The social network model further suggests that the epidemiological observations from the 2000 km2 Serengeti study area may not have reflected the larger-scale dynamics because the sample was (1) located at the periphery of the pride-pride contact network and (2) confined to a small region relative to the scale of the ecosystem. If lions could not produce the observed CDV outbreak, and other wild carnivores were repeatedly involved in transmission to the lion population, could a multi-host spatial model account for the patchy pattern of CDV spread seen in lions in 1994? A stochastic susceptible-infected-recovered model was constructed which allowed transmission between a highly territorial species, like lions, and 1-2 more gregarious hosts, such as hyenas and jackals. When other gregarious species were coupled with lions with low interspecific contact rates, the erratic patterns of CDV spatial spread were similar to those seen in lions in 1994. The results of both the network and the multi-host models suggest that lions are a non-maintenance population for canine distemper virus, and more broadly address issues of spatial disease ecology and multi-host pathogens in complex ecosystems.

Subjects/Keywords: African Lion; Canine Distemper Virus; Disease Transmission; Multihost Model; Network Model; Social Structure; Ecology, Evolution and Behavior

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Craft, M. E. (2008). Predicting disease dynamics in African lion populations. (Thesis). University of Minnesota. Retrieved from http://purl.umn.edu/46993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Craft, Meggan E. “Predicting disease dynamics in African lion populations.” 2008. Thesis, University of Minnesota. Accessed March 05, 2021. http://purl.umn.edu/46993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Craft, Meggan E. “Predicting disease dynamics in African lion populations.” 2008. Web. 05 Mar 2021.

Vancouver:

Craft ME. Predicting disease dynamics in African lion populations. [Internet] [Thesis]. University of Minnesota; 2008. [cited 2021 Mar 05]. Available from: http://purl.umn.edu/46993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Craft ME. Predicting disease dynamics in African lion populations. [Thesis]. University of Minnesota; 2008. Available from: http://purl.umn.edu/46993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. Guiserix, Micheline. Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations.

Degree: Docteur es, Écologie évolutive et épidémiologie, 2009, Université Claude Bernard – Lyon I

URL: http://www.theses.fr/2009LYO10094

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Le travail présenté dans ce manuscrit traite des mécanismes d'émergence des maladies infectieuses. Une première partie du texte est consacrée à la réflexion menée sur… (more)

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Le travail présenté dans ce manuscrit traite des mécanismes d'émergence des maladies infectieuses. Une première partie du texte est consacrée à la réflexion menée sur ces processus, et à leurs conséquences pour la gestion des maladies. Dans une deuxième partie nous exposons les travaux de modélisation réalisés ; l’objectif est de tester si des changements dans l'expression d'une infection peuvent être expliqués par la dynamique de circulation de l'agent infectieux dans la population hôte, à travers la protection de groupe. Nous montrons que l'apparition de la maladie de Carré chez les lions du Serengeti peut être due à une perte d’immunité de groupe suite à l’extinction du virus. Nous étudions ensuite les conséquences sur le patron épidémique d'une protection partiellement croisée entre souches. Enfin, nous intégrons à cette problématique la structure spatiale de la population hôte, pour expliquer des observations faites sur les systèmes lagomorphes/lagovirus en France.

The study presented here aims to suggest and to test several mechanisms to explain how infectious diseases impact could increase, in relation to microparasite circulation and loss of herd protection. We first introduce the main characteristics of host/microparasite interaction and display some knowledge about emerging infectious diseases, and their consequences for diseases control. Stochastic modelling is then used to study epidemic patterns under several hypotheses and for different host/parasite systems: i) we explain canine distemper emergence in Serengeti lions through a break in virus circulation and the resulting loss of herd immunity; ii) we study the consequences of partial crossprotection induced in hosts by different strains in a small homogeneous host population; and iii) we extend this study to spatially structured host populations to explain data observed in lagomorphs/lagoviruses in France.

Advisors/Committee Members: Pontier, Dominique (thesis director).

Subjects/Keywords: Maladies infectieuses; Émergence; Modélisation dynamique stochastique; Patron épidémique; Immunité de groupe; Protection partiellement croisée; Maladie de Carré; Lions du Serengeti; Maladie hémorragique du lapin; Syndrome du lièvre brun européen; Infectious diseases; Emergence; Dynamic modelling; Stochastic models; Epidemic patterns; Herd immunity; Partial cross-protection; Canine distemper disease; Serengeti lions; Rabbit hemorrhagic disease (RHD); European brown hare syndrome (EBHS)

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APA (6^th Edition):

Guiserix, M. (2009). Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations. (Doctoral Dissertation). Université Claude Bernard – Lyon I. Retrieved from http://www.theses.fr/2009LYO10094

Chicago Manual of Style (16^th Edition):

Guiserix, Micheline. “Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations.” 2009. Doctoral Dissertation, Université Claude Bernard – Lyon I. Accessed March 05, 2021. http://www.theses.fr/2009LYO10094.

MLA Handbook (7^th Edition):

Guiserix, Micheline. “Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations.” 2009. Web. 05 Mar 2021.

Vancouver:

Guiserix M. Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations. [Internet] [Doctoral dissertation]. Université Claude Bernard – Lyon I; 2009. [cited 2021 Mar 05]. Available from: http://www.theses.fr/2009LYO10094.

Council of Science Editors:

Guiserix M. Mécanismes d’émergence des maladies infectieuses : étude par la modélisation du rôle de la protection de groupe, dans des populations hôtes homogènes ou structurées spatialement : Emerging infectious diseases : the role of herd protection loss due to stochastic fluctuations in microparasite circulation, within both well-mixed and spatially structured host populations. [Doctoral Dissertation]. Université Claude Bernard – Lyon I; 2009. Available from: http://www.theses.fr/2009LYO10094

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