subject:(Campylobacter)

Massey University

1. Yu, Shoukai. The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand .

Degree: 2012, Massey University

URL: http://hdl.handle.net/10179/4840

► The genus Campylobacter is a major cause of human gastroenteritis worldwide, so understanding the evolution of Campylobacter has important implications. This multidisciplinary project uni es… (more)

▼ The genus Campylobacter is a major cause of human gastroenteritis worldwide, so understanding the evolution of Campylobacter has important implications. This multidisciplinary project uni es developments from statistics, genetics, bioinformatics and computer science and creates a good opportunity to investigate the evolution of Campylobacter by focusing on the factors which a ect genetic exchange. In order to understand how Campylobacter evolves, a mathematical method is put forward to estimate the relative rates of recombination and mutation in generating new alleles that lead to single locus variants (SLVs), and examine the e ect of selection, recombination and mutation. This analysis shows the importance of recombination in the evolution of Campylobacter and larger contribution made by recombination, compared to mutation, in the evolution of Campylobacter jejuni, and Campylobacter coli. In addition, this research demonstrates that purifying selection plays an important role in the evolution of Campylobacter. For comparison, this analysis also examined the role played by recombination in the evolution of other bacteria. This application highlighted the importance of recombination for creating diversity in closely related isolates. A range of phylogenetic and population genetic tools were applied to investigate the e ect of geographical isolation on the evolution of Campylobacter by comparing datasets from two geographically separated countries, New Zealand and the United Kingdom, this is the rst time this has been attempted. Analysing sequence data at di erent levels of resolution provided evidence that geographical isolation a ects the evolution of Campylobacter genotypes over short time-scales, but that this e ect diminishes over longer time-scales. Furthermore, this analysis estimates the time for divergence of NZ speci c lineages of Campylobacter strains. In New Zealand, Campylobacter jejuni strain type 474 (ST-474) is responsible for more than a quarter of human campylobacteriosis noti cations, but has been rarely found outside NZ. Knowing the clonal relationships of ST-474 strains is helpful for inferring the origin and the evolutionary mechanism of Campylobacter. This research accessed 59 isolates of Campylobacter. It applied a range of phylogenetic tools to targeted gene reference set to compare estimations of the clonal genealogy inferred for Campylobacter datasets. These ndings have implications for identifying the origin of Campylobacter, developing disease intervention strategies, predicting the emergence of pathogens, and reducing the occurrence of campylobacteriosis in the food supply chain.

Subjects/Keywords: Campylobacter

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APA (6^th Edition):

Yu, S. (2012). The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand . (Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/4840

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yu, Shoukai. “The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand .” 2012. Thesis, Massey University. Accessed February 27, 2021. http://hdl.handle.net/10179/4840.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yu, Shoukai. “The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand .” 2012. Web. 27 Feb 2021.

Vancouver:

Yu S. The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand . [Internet] [Thesis]. Massey University; 2012. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10179/4840.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yu S. The evolution of Campylobacter : submitted in partial fulfilment of the requirements for the PhD in Statistical Genetics, mEpiLab, Infectious Disease Research Centre, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, New Zealand . [Thesis]. Massey University; 2012. Available from: http://hdl.handle.net/10179/4840

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University

2. Friedrich, Anja. Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand .

Degree: 2014, Massey University

URL: http://hdl.handle.net/10179/6703

► Campylobacter spp. are a major cause of human gastroenteritis. Their wide host range, environmental distribution and high genetic diversity contribute to the complex molecular epidemiology… (more)

▼ Campylobacter spp. are a major cause of human gastroenteritis. Their wide host range, environmental distribution and high genetic diversity contribute to the complex molecular epidemiology of campylobacteriosis. The aim of this multidisciplinary thesis is to investigate the phenotype:genotype relationships of C. jejuni and how they in uence the micro-evolution of these bacteria in New Zealand. The first study used a time series of genotyped human campylobacteriosis cases from a region of New Zealand to investigate if the clonal complexes (CCs) identified in human cases showed a seasonal pattern. The analysis revealed a prevalent clonal complex (CC-45) which showed a consistent summer peak. The second study applied phylogenetic and population genetic tools to describe the population structure and host associated genotypes within the C. jejuni population in wild and agricultural animals. The findings showed that the C. jejuni isolates from non-agricultural animals exhibit a higher number of mosaic alleles and fewer shared sequence types (STs) between the host groups, whereas the C. jeuni in agricultural animals show a higher number of shared STs and fewer occurrences of admixture. The third study tested the ability of a variety of C. jejuni isolates to utilise 95 substrates as carbon sources and tested their tolerance to different osmotic conditions using phenotypic microarray (PM) technology. These phenotypic expressions were correlated with their genomes and a genome wide association study was used to identify genes associated with the observed phenotype. The last study made use of data from a dual isolate chicken challenge. The study showed the out-competition of one challenge strain and genetic variations of 15 core single nucleotide polymorphisms (SNPs), 14 of which were non-synonymous point mutations. These SNPs were confined to nine genes all of which were associated with cell shape, chemotaxis or motility of the bacteria. This thesis has furthered our understanding of the seasonality of human campylobacteriosis in New Zealand, the existing population structure of C. jejuni, its biochemical requirements and tolerance to osmolytes and novel insights into short-term evolutionary dynamics in vivo. Based on these findings and the recommendations for future directions, this could lead to a greater understanding of host-association and new intervention strategies.

Subjects/Keywords: Campylobacter; Campylobacter jejuni; Campylobacteriosis

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APA (6^th Edition):

Friedrich, A. (2014). Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand . (Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/6703

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Friedrich, Anja. “Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand .” 2014. Thesis, Massey University. Accessed February 27, 2021. http://hdl.handle.net/10179/6703.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Friedrich, Anja. “Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand .” 2014. Web. 27 Feb 2021.

Vancouver:

Friedrich A. Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand . [Internet] [Thesis]. Massey University; 2014. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10179/6703.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Friedrich A. Campylobacter jejuni microevolution and phenotype:genotype relationships : a thesis submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand . [Thesis]. Massey University; 2014. Available from: http://hdl.handle.net/10179/6703

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Tennessee – Knoxville

3. Tweedie, Jessica. Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment.

Degree: MS, Microbiology, 2019, University of Tennessee – Knoxville

URL: https://trace.tennessee.edu/utk_gradthes/5582

► Campylobacter infections are the leading bacterial cause of diarrhea worldwide with potentially profound impacts on pediatric patients in the developing world. It is still unclear… (more)

Subjects/Keywords: Campylobacter; bacterial pathogenesis; campylobacter jejuni

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APA (6^th Edition):

Tweedie, J. (2019). Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment. (Thesis). University of Tennessee – Knoxville. Retrieved from https://trace.tennessee.edu/utk_gradthes/5582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tweedie, Jessica. “Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment.” 2019. Thesis, University of Tennessee – Knoxville. Accessed February 27, 2021. https://trace.tennessee.edu/utk_gradthes/5582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tweedie, Jessica. “Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment.” 2019. Web. 27 Feb 2021.

Vancouver:

Tweedie J. Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment. [Internet] [Thesis]. University of Tennessee – Knoxville; 2019. [cited 2021 Feb 27]. Available from: https://trace.tennessee.edu/utk_gradthes/5582.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tweedie J. Campylobacter infection of young children in a Latin American middle-income country and its impact on the gastrointestinal environment. [Thesis]. University of Tennessee – Knoxville; 2019. Available from: https://trace.tennessee.edu/utk_gradthes/5582

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Debrecen

4. Perjéssy, Judit. Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük .

Degree: DE – TEK – Természettudományi és Technológiai Kar – Biológiai és Ökológiai Intézet, 2012, University of Debrecen

URL: http://hdl.handle.net/2437/152731

A Camyplobacter által okozott fertőzések emberekben és állatokban egyaránt, a betegség kórlefolyása, megelőzése. Valamint a baktérium élelmiszerből történő tenyésztése. Advisors/Committee Members: Csákiné Jäger, Szilvia (advisor).

Subjects/Keywords: Campylobacter; fertőzés

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APA (6^th Edition):

Perjéssy, J. (2012). Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük . (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/152731

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Perjéssy, Judit. “Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük .” 2012. Thesis, University of Debrecen. Accessed February 27, 2021. http://hdl.handle.net/2437/152731.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Perjéssy, Judit. “Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük .” 2012. Web. 27 Feb 2021.

Vancouver:

Perjéssy J. Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük . [Internet] [Thesis]. University of Debrecen; 2012. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2437/152731.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Perjéssy J. Campylobacter fajok által okozott fertőzések és laboratóriumi (élelmiszerből történő) tenyésztésük . [Thesis]. University of Debrecen; 2012. Available from: http://hdl.handle.net/2437/152731

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide

5. Waterman, Scott R. Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman.

Degree: 1992, University of Adelaide

URL: http://hdl.handle.net/2440/21620

Subjects/Keywords: Campylobacter.

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APA (6^th Edition):

Waterman, S. R. (1992). Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/21620

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Waterman, Scott R. “Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman.” 1992. Thesis, University of Adelaide. Accessed February 27, 2021. http://hdl.handle.net/2440/21620.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Waterman, Scott R. “Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman.” 1992. Web. 27 Feb 2021.

Vancouver:

Waterman SR. Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman. [Internet] [Thesis]. University of Adelaide; 1992. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2440/21620.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Waterman SR. Construction of a plasmid shuttle vector for Campylobacter hyointestinalis / Scott R. Waterman. [Thesis]. University of Adelaide; 1992. Available from: http://hdl.handle.net/2440/21620

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University

6. Leyland, Megan Jane. Typing of Campylobacter isolates from humans and animals in New Zealand.

Degree: MS, Microbiology, 1998, Massey University

URL: http://hdl.handle.net/10179/6564

► Campylobacteriosis is currently the most commonly notified communicable disease in New Zealand. The sources of Campylobacter infections are not known, although the consumption of incompletly… (more)

Subjects/Keywords: Campylobacter

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Leyland, M. J. (1998). Typing of Campylobacter isolates from humans and animals in New Zealand. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/6564

Chicago Manual of Style (16^th Edition):

Leyland, Megan Jane. “Typing of Campylobacter isolates from humans and animals in New Zealand.” 1998. Masters Thesis, Massey University. Accessed February 27, 2021. http://hdl.handle.net/10179/6564.

MLA Handbook (7^th Edition):

Leyland, Megan Jane. “Typing of Campylobacter isolates from humans and animals in New Zealand.” 1998. Web. 27 Feb 2021.

Vancouver:

Leyland MJ. Typing of Campylobacter isolates from humans and animals in New Zealand. [Internet] [Masters thesis]. Massey University; 1998. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10179/6564.

Council of Science Editors:

Leyland MJ. Typing of Campylobacter isolates from humans and animals in New Zealand. [Masters Thesis]. Massey University; 1998. Available from: http://hdl.handle.net/10179/6564

North Carolina State University

7. Xiong, Jiajuan. Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization.

Degree: MS, Biotechnology, 2009, North Carolina State University

URL: http://www.lib.ncsu.edu/resolver/1840.16/1045

► Campylobacter spp. is a major cause of acute bacterial gastroenteritis in the developed countries. It can survive in a wide range of environments, raw milk… (more)

▼ Campylobacter spp. is a major cause of acute bacterial gastroenteritis in the developed countries. It can survive in a wide range of environments, raw milk and poultry are major reservoirs. Survival of animal-derived Campylobacter strains, including six C. jejuni and six C. coli, was examined in raw and pasteurized milk at 4 °C. Most (11/12) of the Campylobacter strains survived in both raw and pasteurized milk for at least 14 days. The most resistant strain, a C. jejuni from a dairy cow, retained its viability over eight weeks in pasteurized milk, while the most sensitive strain showed a > 5-log10 CFU/ml reduction in raw milk after one week. The majority (9/12) of the strains survived better in pasteurized milk than in raw milk, while the opposite was observed for two C. coli strains. The findings indicate that Campylobacter spp. can survive in milk for at least 14 days at 4 °C and that survival is strain-dependent. To elucidate mechanisms underlying such adaptation, we characterized the role of capsule in Campylobacter survival in milk and other media, and in chick colonization. Three capsule-deficient mutants (kpsM::kanr), C. coli 6979M2, C. jejuni BS142M2 and C. jejuni SC1453M2 were constructed by site-specific mutagenesis. Compared to the wild type strains, the colonies of the mutants were smaller, more convex, and shinier on agar media; the mutants were more sensitive to desiccation and two (C. coli 6979M2 and C. jejuni BS142M2) grew slower in broth. These two mutants were also more sensitive to certain antibiotics than their wild type counterparts. The survival of the mutants in distilled water, raw and pasteurized milk was comparable to survival of their wild type counterparts, as was the ability of the bacteria to transform to nalidixic acid resistance via transformation. In chick colonization experiment, C. coli 6979 M2 showed > 3log10 reduced cell density in cecal contents than its parent strain. These results suggest that capsule is essential for C. coli in chick colonization and responsible for colony morphology on solid agar and can protect cells from desiccation, but its impact on growth rate, competence and antibiotic resistance is strain-dependent. Advisors/Committee Members: Dr. Sophia Kathariou, Committee Chair (advisor), Dr. Ilenys M. Perez-Diaz, Committee Member (advisor), Dr. Jonathan Olson, Committee Member (advisor).

Subjects/Keywords: capsule; milk; Campylobacter coli; Campylobacter jejuni

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APA (6^th Edition):

Xiong, J. (2009). Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization. (Thesis). North Carolina State University. Retrieved from http://www.lib.ncsu.edu/resolver/1840.16/1045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Xiong, Jiajuan. “Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization.” 2009. Thesis, North Carolina State University. Accessed February 27, 2021. http://www.lib.ncsu.edu/resolver/1840.16/1045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Xiong, Jiajuan. “Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization.” 2009. Web. 27 Feb 2021.

Vancouver:

Xiong J. Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization. [Internet] [Thesis]. North Carolina State University; 2009. [cited 2021 Feb 27]. Available from: http://www.lib.ncsu.edu/resolver/1840.16/1045.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Xiong J. Survival of Animal-derived Campylobacter Strains in Raw and Pasteurized Milk, and the Roles of Capsule in Campylobacter Survival in vitro, and in Chick Colonization. [Thesis]. North Carolina State University; 2009. Available from: http://www.lib.ncsu.edu/resolver/1840.16/1045

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University

8. Fakir, Jayantilal Dullabh. A study of thermophilic campylobacter in cattle, sheep and laboratory animals.

Degree: M. Phil., Veterinary Microbiology, 1986, Massey University

URL: http://hdl.handle.net/10179/4791

► A total of 1107 samples (rectal, intestinal and bile) from rats, mice, guinea pigs, rabbits and cats were examined for the presence of intestinal thermophilic… (more)

▼ A total of 1107 samples (rectal, intestinal and bile) from rats, mice, guinea pigs, rabbits and cats were examined for the presence of intestinal thermophilic campylobacter. The investigation showed that 20.6% of the total of 503 laboratory animals examined were positive for Campylobacter jejuni. The prevalence rate was found to be highest amongst the cats (51.7%) with rats being the next in order (23.2%), whereas 4/52 (7.7%) of guinea pigs and a single rabbit (1%) were positive for C. jejuni. One of the four isolates recovered from guinea pigs was from bile. Campylobacter-like organisms were cultured from 5/50 (10%) of the mice, but these failed to grow on subsequent subculturing. By using bacterial restriction endonuclease DNA analysis (BRENDA) for their identification, a single type of C. jejuni was identified (pattern 25) from all isolates recovered from the rats, guinea pigs and a rabbit, whereas there were five different BRENDA patterns from cat isolates. Sawdust was suggested as a likely vehicle through which the organism may have spread within the Unit and infected the rats. The spread to other species was thought to have been from the guinea pigs which were initially infected from contaminated hay or green feed. The isolation of C. jejuni organisms having a multiplicity of BRENDA patterns from the cats, suggests that the cat organisms had been present in the cat colony from the time the colony was started or from the occasional bird which accidentally flew into the cat cages and was eaten. A single isolate of C. laridis from a house fly was also isolated but there was no evidence of this organism in any of the laboratory animals. Seasonal variations in the isolation of thermophilic Campylobacter species in dairy cows was also studied and showed that there were 17/72 (23.6%), 33/106 (31.13%) and 11/95 (11.5%) positive for campylobacter during summer, autumn and winter respectively. The prevalence rate of Campylobacter species is highest in warmer months of the year. The isolates recovered from dairy cows were also identified by the BRENDA technique and compared with those from sheep. Seventeen different BRENDA patterns were identified from 48 isolates from dairy cows and six from 27 isolates from sheep. Of the total of 21 different BRENDA patterns, only two were common to both animals Suggesting cross infectivity between these two animals. Organisms having the same BRENDA pattern could also be isolated from dairy cows and sheep on more than one occasion establishing the stability of BRENDA patterns. No similarities were seen between the BRENDA patterns recovered from laboratory animal isolates and those of dairy cows and sheep.

Subjects/Keywords: Campylobacter; Campylobacter jejuni

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APA (6^th Edition):

Fakir, J. D. (1986). A study of thermophilic campylobacter in cattle, sheep and laboratory animals. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/4791

Chicago Manual of Style (16^th Edition):

Fakir, Jayantilal Dullabh. “A study of thermophilic campylobacter in cattle, sheep and laboratory animals.” 1986. Masters Thesis, Massey University. Accessed February 27, 2021. http://hdl.handle.net/10179/4791.

MLA Handbook (7^th Edition):

Fakir, Jayantilal Dullabh. “A study of thermophilic campylobacter in cattle, sheep and laboratory animals.” 1986. Web. 27 Feb 2021.

Vancouver:

Fakir JD. A study of thermophilic campylobacter in cattle, sheep and laboratory animals. [Internet] [Masters thesis]. Massey University; 1986. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10179/4791.

Council of Science Editors:

Fakir JD. A study of thermophilic campylobacter in cattle, sheep and laboratory animals. [Masters Thesis]. Massey University; 1986. Available from: http://hdl.handle.net/10179/4791

University of New South Wales

9. Burgos-Portugal, Jose. Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus.

Degree: Biotechnology & Biomolecular Sciences, 2015, University of New South Wales

URL: http://handle.unsw.edu.au/1959.4/54996 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36341/SOURCE02?view=true

► Campylobacter ureolyticus and Campylobacter concisus are emerging pathogens that have been associated with gastrointestinal disease. Detection of these bacteria in faecal samples of patients with… (more)

▼ Campylobacter ureolyticus and Campylobacter concisus are emerging pathogens that have been associated with gastrointestinal disease. Detection of these bacteria in faecal samples of patients with gastroenteritis, and intestinal biopsies and faecal samples of patients with Crohn’s disease, led us to investigate the pathogenic mechanisms used by both C. ureolyticus and C. concisus to infect host cells and cause gastrointestinal disease. Investigation of the ability of C. ureolyticus to interact with intestinal epithelial cell lines showed that it was able to adhere to both Caco-2 and HT-29 cell lines. This was confirmed using scanning electron microscopy (ScEM), showing that C. ureolyticus UNSWCD employed a “sticky-end” mechanism to attach to the microvilli of Caco-2 cells resulting in cellular damage and microvilli degradation. In contrast, gentamicin protection assays revealed that C. ureolyticus was unable to invade either cell line, a finding confirmed by ScEM. Furthermore, addition of pro-inflammatory cytokines TNF-α and IFN-γ to these cell lines prior to infection had no effect on attachment or invasion. Investigation of the secretome of C. ureolyticus UNSWCD revealed the presence of putative virulence and colonisation factors.Given that previous studies had demonstrated varying abilities of C. concisus strains to invade intestinal cell lines, this thesis explored the potential of C. concisus strains to survive within host cells by manipulating the autophagy process. Gentamicin protection assays revealed that autophagy inhibition resulted in 2-4 fold increases in intracellular levels of C. concisus UNSWCD within Caco-2 cells, whereas autophagy induction resulted in a reduction in intracellular levels or bacterial clearance. Confocal laser scanning microscopy showed co-localisation of the bacterium within autophagosomes, while an optimised transmission electron microscopy procedure identified intracellular bacteria persisting within autophagic vesicles. Furthermore, qPCR showed that 13 genes in the autophagy process were significantly regulated following C. concisus infection. Overall, these findings revealed that C. concisus UNSWCD elicits a dampening effect on the autophagy process. The studies from this thesis have significantly increased our understanding of the pathogenic mechanisms used by these bacteria to interact with and manipulate host intestinal cells and potentially cause gastrointestinal disease. Advisors/Committee Members: Mitchell , Hazel , Biotechnology & Biomolecular Sciences, Faculty of Science, UNSW, Kaakoush, Nadeem , Biotechnology & Biomolecular Sciences, Faculty of Science, UNSW.

Subjects/Keywords: Autophagy; Campylobacter ureolyticus; Campylobacter concisus; Pathogenesis

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APA (6^th Edition):

Burgos-Portugal, J. (2015). Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/54996 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36341/SOURCE02?view=true

Chicago Manual of Style (16^th Edition):

Burgos-Portugal, Jose. “Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus.” 2015. Doctoral Dissertation, University of New South Wales. Accessed February 27, 2021. http://handle.unsw.edu.au/1959.4/54996 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36341/SOURCE02?view=true.

MLA Handbook (7^th Edition):

Burgos-Portugal, Jose. “Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus.” 2015. Web. 27 Feb 2021.

Vancouver:

Burgos-Portugal J. Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus. [Internet] [Doctoral dissertation]. University of New South Wales; 2015. [cited 2021 Feb 27]. Available from: http://handle.unsw.edu.au/1959.4/54996 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36341/SOURCE02?view=true.

Council of Science Editors:

Burgos-Portugal J. Investigation into the pathogenic potential of the emergent gastrointestinal pathogens Campylobacter ureolyticus and Campylobacter concisus. [Doctoral Dissertation]. University of New South Wales; 2015. Available from: http://handle.unsw.edu.au/1959.4/54996 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:36341/SOURCE02?view=true

University of Guelph

10. Deckert, Anne. Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario.

Degree: PhD, Population Medicine, 2012, University of Guelph

URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4063

► This thesis is an investigation of human campylobacteriosis and Campylobacter from retail chicken in two Ontario health units. The objectives were to investigate the symptoms,… (more)

▼ This thesis is an investigation of human campylobacteriosis and Campylobacter from retail chicken in two Ontario health units. The objectives were to investigate the symptoms, severity, antimicrobial use (AMU), antimicrobial resistance (AMR), and duration of illness (DI) in clinical campylobacteriosis, the prevalence and AMR of Campylobacter from contaminated retail chicken, and the relationship between clinical and chicken Campylobacter isolates based on Comparative Genomic Fingerprinting (CGF). In the participating health units, campylobacteriosis case data were collected and retail chicken was sampled from randomly selected stores. Campylobacter isolates from clinical cases and chicken were antimicrobial susceptibility tested and CGF typed. A Cox proportional hazard model was used to investigate the DI in campylobacteriosis. Logistic regression models were used to explore the relationship between clinical and chicken CGF types. Of 250 cases, 52% reported taking antimicrobials for their campylobacteriosis. In 124 cases with accompanying isolate and AMR information, 6 (4.8%) and 2 (1.6%) isolates were resistant to ciprofloxacin and erythromycin, respectively. In 749 chicken isolates, 14 (1.9%) and 25 (3.3%) isolates were resistant to ciprofloxacin and erythromycin, respectively. No isolates were resistant to both antimicrobials. While the low prevalence of AMR to ciprofloxacin and erythromycin was encouraging, the high proportion of cases treated with antimicrobials was concerning and efforts should be made to reduce unnecessary treatment. The Cox model identified that use of a macrolide for less than the recommended duration, use of ciprofloxacin for the recommended duration, and use of other antimicrobials, were factors associated with decreased DI. The impact of AMU was consistent regardless of when in the course of illness it began. The CGF results were available from 115 clinical and 718 chicken isolates. A Campylobacter CGF reference database was used to identify CGF types that comprised at least 80% of isolates from chicken, based on 90% fingerprint similarity (CA90). Isolates from urban cases were significantly more likely than rural cases to be CA90. In Canada, the majority of campylobacteriosis cases are urban dwellers. Therefore, the association between urban cases and CA90 emphasizes the importance of Campylobacter from retail chicken on public health. Advisors/Committee Members: McEwen, Scott (advisor).

Subjects/Keywords: Campylobacter; chicken; human

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Deckert, A. (2012). Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4063

Chicago Manual of Style (16^th Edition):

Deckert, Anne. “Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario.” 2012. Doctoral Dissertation, University of Guelph. Accessed February 27, 2021. https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4063.

MLA Handbook (7^th Edition):

Deckert, Anne. “Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario.” 2012. Web. 27 Feb 2021.

Vancouver:

Deckert A. Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario. [Internet] [Doctoral dissertation]. University of Guelph; 2012. [cited 2021 Feb 27]. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4063.

Council of Science Editors:

Deckert A. Campylobacter in Human Cases and Retail Chicken in two Health Units in Ontario. [Doctoral Dissertation]. University of Guelph; 2012. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4063

University of Debrecen

11. Tóth, Renáta. A Campylobacter humán és élelmiszerláncban betöltött szerepe .

Degree: DE – ATC – Mezőgazdaság- Élelmiszertudományi és Környezetgazdálkodási Kar, 2013, University of Debrecen

URL: http://hdl.handle.net/2437/169842

► Diplomadolgozatom célja az volt, hogy bemutassam a C. jejuni morfológiáját, kimutatását, fertőzést hordozó élelmiszerek körét, az általa okozott campylobacteriosis tüneteit emberben és állatban, a megbetegedések… (more)

▼ Diplomadolgozatom célja az volt, hogy bemutassam a C. jejuni morfológiáját, kimutatását, fertőzést hordozó élelmiszerek körét, az általa okozott campylobacteriosis tüneteit emberben és állatban, a megbetegedések és fertőzöttség alakulását az Európai Unióban és Magyarországon. A C. jejuni morfológiai tulajdonságai alapján megállapíthatjuk, hogy a környezeti tényezőkre igen érzékeny baktérium. Életben maradásához és szaporodásához mikroaerofil körülmények, magas hőmérséklet 37-40°C, kevesebb, mint 2% NaCl tartalom és pH 6,5-7,5 szükséges. A C. jejuni tizedelési ideje 50°C-on 1-6,3 perc, 55°C-on 0,6-2,3 perc, 60°C-on 0,2- 0,3 perc. Az ellenálló képessége kicsi. A napfény gyorsan elpusztítja, érzékeny a levegő oxigénjére. Alacsony hőmérsékleten nem szaporodik, a hűtést és fagyasztást heteken, hónapokon keresztül kibírja. A Campylobacter spp. kimutatása az MSZ EN ISO 10272-1:2006 szabvány szerint történik. A Campylobacter fajok természetes viszonyok között a madarak bélcsatornájának lakója. Állati eredetű élelmiszerekbe, a nyers húsba az állatok levágása után, a tejbe a bélsárral, természetes vizekbe pedig szennyvizek által kerülhetnek be. Diplomadolgozatom összegyűjtött adatok alapján megállapítottam, hogy a húsok közül a broiler-hús a Campylobacter-rel legnagyobb mértékben kontaminálódott húsfajta. Európai Uniós és magyarországi eredmények bizonyítják, hogy a marhahús, a sertéshús és a tej csak kis számban fertőződhet. Campylobacteriosis tünetei emberben a hasmenés mellett a hőemelkedés, a láz, a hasi fájdalom, a rossz közérzet, a hányinger és a hányás is. A betegség 2-5 nap alatt, de max. 7-10 nap alatt magától gyógyul. Ritka szövődménye lehet: a polyneuropathia (Guillain-Barre szindróma) vagy a hemolitikus urémiás szindróma (HUS). A juhokban és szarvasmarhákban C. jejuni, C. coli vetélést okozhat. Előidézhet újszülött borjakban hasmenést, fejőstehenekben mastitist. A madarakban a C. jejuni septikaemiával járó májgyulladást okozhat. A C. jejuni a tojásba nem jut be, a napos csibék fertőzésektől mentesek. Az Európai Unióban 2011-ben a bizonyított campylobacteriosis-esetek száma 220 209, mely számadat 2005 óta folyamatosan növekszik. Magyarországon a bizonyított esetek száma 6 121, mely 61.3 /100 000 lakos. Az Európai Unióban és Magyarországon is a campylobacteriosis száma meghaladja a szalmonellózis számát. A NÉBIH ÉTBI debreceni Regionális Élelmiszerlánc Laboratóriumában végzett élelmiszer monitoring vizsgálatok eredményeként megállapítottam, hogy Campylobacterrel legszennyezettebbek a baromfihúsok. A kontaminált baromfihús minták száma vágóhídon és a kereskedelemben a legnagyobb, mely megegyezik az Európai Uniós adatokkal. A vizsgált pozitív élelmiszerminták megoszlása 45% C. coli, 27% C. jejuni, 29% nem kitenyészthető. Az Európai Unióban Campylobacter-re mikrobiológiai határérték nincs meghatározva. Az élelmiszerláncban működő üzemek vizsgálatokat Campylobacter-re nem végeznek. Campylobacter pozitív élelmiszerminta esetén csak élelmiszerlánc visszacsatolás történik. Advisors/Committee Members: Peles, Ferenc Árpád (advisor).

Subjects/Keywords: Campylobacter; élelmiszerbiztonság; élelmiszerhigiénia

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APA (6^th Edition):

Tóth, R. (2013). A Campylobacter humán és élelmiszerláncban betöltött szerepe . (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/169842

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tóth, Renáta. “A Campylobacter humán és élelmiszerláncban betöltött szerepe .” 2013. Thesis, University of Debrecen. Accessed February 27, 2021. http://hdl.handle.net/2437/169842.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tóth, Renáta. “A Campylobacter humán és élelmiszerláncban betöltött szerepe .” 2013. Web. 27 Feb 2021.

Vancouver:

Tóth R. A Campylobacter humán és élelmiszerláncban betöltött szerepe . [Internet] [Thesis]. University of Debrecen; 2013. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2437/169842.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tóth R. A Campylobacter humán és élelmiszerláncban betöltött szerepe . [Thesis]. University of Debrecen; 2013. Available from: http://hdl.handle.net/2437/169842

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape

12. Peyrot, Belinda Margaret. A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) .

Degree: 2014, University of the Western Cape

URL: http://hdl.handle.net/11394/4155

► Campylobacter and related Epsilonproteobacteria (Arcobacter and Helicobacter) are currently viewed as emerging pathogens and are able to cause gastroenteritis, bacteraemia, the Guillain-Barré syndrome, reactive arthritis… (more)

Subjects/Keywords: Ostrich; Campylobacter; Microbiology

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APA (6^th Edition):

Peyrot, B. M. (2014). A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/4155

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Peyrot, Belinda Margaret. “A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) .” 2014. Thesis, University of the Western Cape. Accessed February 27, 2021. http://hdl.handle.net/11394/4155.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Peyrot, Belinda Margaret. “A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) .” 2014. Web. 27 Feb 2021.

Vancouver:

Peyrot BM. A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) . [Internet] [Thesis]. University of the Western Cape; 2014. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/11394/4155.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Peyrot BM. A microbiological and molecular study of campylobacter and related species isolated from ostriches (Struthio camelus) . [Thesis]. University of the Western Cape; 2014. Available from: http://hdl.handle.net/11394/4155

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

13. Taylor, Zane W. Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni.

Degree: PhD, Biochemistry, 2020, Texas A&M University

URL: http://hdl.handle.net/1969.1/191886

► Campylobacter jejuni is a Gram-negative pathogenic bacterium that is the leading cause of gastroenteritis worldwide. Like many other Gram-negative bacteria, C. jejuni produces a capsular… (more)

Subjects/Keywords: Phosphoramidate; Campylobacter jejuni

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APA (6^th Edition):

Taylor, Z. W. (2020). Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/191886

Chicago Manual of Style (16^th Edition):

Taylor, Zane W. “Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni.” 2020. Doctoral Dissertation, Texas A&M University. Accessed February 27, 2021. http://hdl.handle.net/1969.1/191886.

MLA Handbook (7^th Edition):

Taylor, Zane W. “Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni.” 2020. Web. 27 Feb 2021.

Vancouver:

Taylor ZW. Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni. [Internet] [Doctoral dissertation]. Texas A&M University; 2020. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/1969.1/191886.

Council of Science Editors:

Taylor ZW. Biosynthesis of the O-Methyl Phosphoramidate Modification in the Capsular Polysaccharides of Campylobacter jejuni. [Doctoral Dissertation]. Texas A&M University; 2020. Available from: http://hdl.handle.net/1969.1/191886

University of the Western Cape

14. Basardien, Laeeqa. Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa .

Degree: 2012, University of the Western Cape

URL: http://hdl.handle.net/11394/5068

► Campylobacter species are the most common bacteria associated with acute diarrhoea and is responsible for 400 to 500 million reported cases globally. It is not… (more)

▼ Campylobacter species are the most common bacteria associated with acute diarrhoea and is responsible for 400 to 500 million reported cases globally. It is not uncommon for 35% to 85% of chicken flocks to be infected with campylobacters and it is because of this high prevalence that chicken is considered to be the primary source of Campylobacter contamination in the domestic setting. Therefore, a very high risk of acquiring campylobacteriosis is associated with the mishandling and consumption of contaminated chicken. The present study had isolated a total number of 156 Campylobacter isolates, of which 102 isolates were C. jejuni and 51 were C. coli. The speciation of 3 Campylobacter isolates could not be determined. It had shown that there is a high prevalence of Campylobacter in South African chicken. Retail chicken (n = 84) has a lower prevalence of 27% whereas chicken sampled directly from the abattoir (n = 182), but also intended for human consumption, had an average prevalence of 73%. It also showed that free range chicken (n = 118) has a higher prevalence (average of 79%) of Campylobacter than commercial chicken (n = 64) (average of 56%). It is for this reason that free range chicken is not always the safer option considering that the purchasing of free range chicken is becoming more popular for health reasons. There is no standardized universal isolation protocol for Campylobacter species and the current isolation techniques creates a bias for the optimal growth of C. jejuni and C. coli, the two thermotolerant species most commonly associated with human illnesses. Recently, the non-selective Cape Town Protocol was designed for efficient isolation of campylobacters from clinical samples and proved to be superior to the former techniques in the isolation of the thermotolerant campylobacters as well as emerging campylobacters. However, the protocol is not suited to the isolation of Campylobacter from food samples. This study successfully optimized the Cape Town protocol by incorporating the use of the selective Bolton broth for the recovery and enrichment of injured cells from raw chicken samples. The technique proved to be equal in isolation efficiency to the ISO 1272-1:2006 method but loses its ability to recover all campylobacters that may be present in the food sample. It is for this reason that a non selective enrichment broth should be sought but the technique boasts superiority over the ISO 10272-1:2006 method in that it reduces the time in obtaining the results at least by 48 h and is more cost effective. Advisors/Committee Members: Gouws, P.A (advisor), Lastovica, A.J (advisor).

Subjects/Keywords: Campylobacter; Campylobacter infections in poultry; Campylobacter infections; Chickens

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APA (6^th Edition):

Basardien, L. (2012). Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/5068

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Basardien, Laeeqa. “Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa .” 2012. Thesis, University of the Western Cape. Accessed February 27, 2021. http://hdl.handle.net/11394/5068.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Basardien, Laeeqa. “Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa .” 2012. Web. 27 Feb 2021.

Vancouver:

Basardien L. Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa . [Internet] [Thesis]. University of the Western Cape; 2012. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/11394/5068.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Basardien L. Molecular characterization of Campylobacter isolates from free range and commercial chicken in South Africa . [Thesis]. University of the Western Cape; 2012. Available from: http://hdl.handle.net/11394/5068

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Massey University

15. Kuhait, Jabbar Gh. Campylobacter infection in intestinal organ cultures.

Degree: M. Phil., Veterinary Pathology, 1987, Massey University

URL: http://hdl.handle.net/10179/5255

► Six different media (T199 medium, T199 + 10% foetal calf serum, T8 medium, T8 + 10% foetal calf serum, RPMI medium and RPMI + 10%… (more)

Subjects/Keywords: Campylobacter; Campylobacter jejuni; Campylobacter infections

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APA (6^th Edition):

Kuhait, J. G. (1987). Campylobacter infection in intestinal organ cultures. (Masters Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/5255

Chicago Manual of Style (16^th Edition):

Kuhait, Jabbar Gh. “Campylobacter infection in intestinal organ cultures.” 1987. Masters Thesis, Massey University. Accessed February 27, 2021. http://hdl.handle.net/10179/5255.

MLA Handbook (7^th Edition):

Kuhait, Jabbar Gh. “Campylobacter infection in intestinal organ cultures.” 1987. Web. 27 Feb 2021.

Vancouver:

Kuhait JG. Campylobacter infection in intestinal organ cultures. [Internet] [Masters thesis]. Massey University; 1987. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10179/5255.

Council of Science Editors:

Kuhait JG. Campylobacter infection in intestinal organ cultures. [Masters Thesis]. Massey University; 1987. Available from: http://hdl.handle.net/10179/5255

Texas A&M University

16. Horrocks, Shane Michael. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro.

Degree: MS, Nutrition, 2007, Texas A&M University

URL: http://hdl.handle.net/1969.1/5022

► Campylobacter is an important human pathogen that colonizes the gut of food producing animals. In this study, the effects of 2-nitro-1-propanol, 2-nitroethanol, nitroethane, and 2-nitro-methyl-propionate… (more)

Subjects/Keywords: Campylobacter; nitrocompound

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APA (6^th Edition):

Horrocks, S. M. (2007). Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/5022

Chicago Manual of Style (16^th Edition):

Horrocks, Shane Michael. “Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro.” 2007. Masters Thesis, Texas A&M University. Accessed February 27, 2021. http://hdl.handle.net/1969.1/5022.

MLA Handbook (7^th Edition):

Horrocks, Shane Michael. “Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro.” 2007. Web. 27 Feb 2021.

Vancouver:

Horrocks SM. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. [Internet] [Masters thesis]. Texas A&M University; 2007. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/1969.1/5022.

Council of Science Editors:

Horrocks SM. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. [Masters Thesis]. Texas A&M University; 2007. Available from: http://hdl.handle.net/1969.1/5022

17. Leahy, Alicia. An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas.

Degree: PhD, Medical Sciences, 2017, Texas A&M University

URL: http://hdl.handle.net/1969.1/161379

► Salmonella and Campylobacter are bacterial pathogens frequently affecting both humans and animals. Even so, there is limited information concerning the epidemiology of these pathogens among… (more)

▼ Salmonella and Campylobacter are bacterial pathogens frequently affecting both humans and animals. Even so, there is limited information concerning the epidemiology of these pathogens among canines. Dogs are capable of shedding the bacteria in their feces, often without overt signs of infection. As a result of their close contact with people, dogs could thus play a significant role in disease transmission, exposing their human companions to the bacterial pathogens. In order to fully assess this risk and implement efficacious means of disease control and prevention, however, it is essential to have a more comprehensive understanding of pathogen distribution and determinants as they relate to canine populations. To that end, the present research investigated the epidemiology of Salmonella and Campylobacter fecal shedding among shelter dogs across Texas using both culture-based and molecular methods. Culture detected Salmonella in 27 (5%) of the 554 samples. Salmonella isolates were of many different serotypes, five of which have been among top 10 serotypes isolated from human patients with laboratory-confirmed salmonellosis in the United States. Antimicrobial resistance among the isolates was minimal. Data analysis suggested that fecal consistency may be an indicator of the fecal presence of Salmonella, and that the effects of dog neuter status and dog origin deserve further attention. For Campylobacter, qPCR suggested a bacterial prevalence of 76% (140 of the 185 samples). Nonetheless, prevalence of two main human pathogens—Campylobacter coli and Campylobacter jejuni—was undetected or low, at 0% and 5.4%, respectively. Statistical assessment of putative shedding indicators demonstrated a possible relationship between the presence of fecal Campylobacter, dog sex, and dog duration of stay in shelter. Campylobacter detection was heavily dependent on the detection method(s) employed. The qPCR method used in the present research proved to be much faster and more sensitive relative to various culture-based techniques. As such, qPCR may be most useful as an adjunct to bacterial culture, perhaps serving to guide selection of an optimal approach to culture. Integral to any approach, however, must be the recognition that canines are clear participants in Salmonella and Campylobacter epidemiology, and their contributions hold substantial import for their close companions. Advisors/Committee Members: Cummings, Kevin (advisor), Hamer, Sarah (committee member), Lawhon, Sara (committee member), Lillibridge, Scott (committee member), Leibowitz, Julian (committee member).

Subjects/Keywords: Salmonella; Campylobacter; Shelter Dogs

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APA (6^th Edition):

Leahy, A. (2017). An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/161379

Chicago Manual of Style (16^th Edition):

Leahy, Alicia. “An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas.” 2017. Doctoral Dissertation, Texas A&M University. Accessed February 27, 2021. http://hdl.handle.net/1969.1/161379.

MLA Handbook (7^th Edition):

Leahy, Alicia. “An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas.” 2017. Web. 27 Feb 2021.

Vancouver:

Leahy A. An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas. [Internet] [Doctoral dissertation]. Texas A&M University; 2017. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/1969.1/161379.

Council of Science Editors:

Leahy A. An Epidemiologic Investigation of Salmonella and Campylobacter Shedding Among Shelter Dogs in Texas. [Doctoral Dissertation]. Texas A&M University; 2017. Available from: http://hdl.handle.net/1969.1/161379

Texas A&M University

18. Garcia, Javier Shalin. Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens.

Degree: MS, Poultry Science, 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151008

► The control of foodborne pathogens especially Salmonella and Campylobacter are of great concern to the commercial poultry industry. The control of these pathogens could be… (more)

Subjects/Keywords: Salmonella; Campylobacter; Vaccines; Poultry

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APA (6^th Edition):

Garcia, J. S. (2013). Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151008

Chicago Manual of Style (16^th Edition):

Garcia, Javier Shalin. “Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens.” 2013. Masters Thesis, Texas A&M University. Accessed February 27, 2021. http://hdl.handle.net/1969.1/151008.

MLA Handbook (7^th Edition):

Garcia, Javier Shalin. “Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens.” 2013. Web. 27 Feb 2021.

Vancouver:

Garcia JS. Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens. [Internet] [Masters thesis]. Texas A&M University; 2013. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/1969.1/151008.

Council of Science Editors:

Garcia JS. Evaluation of Vaccines on the Prevalence of Salmonella and/or Campylobacter in Layer and Broiler Chickens. [Masters Thesis]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151008

University of Guelph

19. DePass, Christina Marie. Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof.

Degree: MS, Department of Chemistry, 2011, University of Guelph

URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3192

► Campylobacter jejuni (C. jejuni) is a food-borne bacterial pathogen that is the leading cause of Traveller’s Diaharea and Guillian-Barré Syndrome. Previous research determined that bacterial… (more)

Subjects/Keywords: Campylobacter; capsular polysaccharide; vaccine; pathogen

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APA (6^th Edition):

DePass, C. M. (2011). Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3192

Chicago Manual of Style (16^th Edition):

DePass, Christina Marie. “Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof.” 2011. Masters Thesis, University of Guelph. Accessed February 27, 2021. https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3192.

MLA Handbook (7^th Edition):

DePass, Christina Marie. “Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof.” 2011. Web. 27 Feb 2021.

Vancouver:

DePass CM. Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof. [Internet] [Masters thesis]. University of Guelph; 2011. [cited 2021 Feb 27]. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3192.

Council of Science Editors:

DePass CM. Campylobacter jejuni Serotype HS:10 Capsular Polysaccharide and the Conjugate Vaccine thereof. [Masters Thesis]. University of Guelph; 2011. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/3192

University of Texas Southwestern Medical Center

20. Barrero-Tobon, Angelica M. Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni.

Degree: 2013, University of Texas Southwestern Medical Center

URL: http://hdl.handle.net/2152.5/2713

► Campylobacter jejuni is the leading cause of bacterial gastroenteritis in humans throughout the world. In contrast to infection of humans, C. jejuni is a commensal… (more)

▼ Campylobacter jejuni is the leading cause of bacterial gastroenteritis in humans throughout the world. In contrast to infection of humans, C. jejuni is a commensal organism of the intestinal tracts of wild and agriculturally-significant animals and avian species. Flagellar motility is the only virulence and colonization factor proven to be required for infection of human volunteers to promote disease and infection of poultry for commensalism. Expression of many flagellar genes is dependent on two alternative sigma factors, σ54 and σ28. Μany rod and hook genes are dependent on σ54 for expression, whereas σ28 is involved in the expression of the major flagellin and other filament genes. We investigated the σ28 regulon and identified five genes that are dependent on σ28 and flagellar components for maximal expression, but are not required for motility. One gene, ciaI, has previously been shown to function in intracellular survival after invasion of human intestinal epithelial cells. The four remaining genes, which we annotated as fedA-fedD (for flagellar co-expressed determinants), encode proteins that have not been characterized. Mutants lacking any one of these feds or ciaI demonstrated a reduced commensal colonization capacity in a natural chick model of colonization. Similar to the σ28-dependent gene product FspA1, a subset of these Feds is secreted by the bacterium in a flagellar-dependent manner. To further investigate the secretion requirements of these σ28-dependent proteins (FedB, CiaI and FspA1), we examined putative flagellar chaperones, flagellar components and other aspects of flagellar biosynthesis such as flagellar protein glycosylation for a role in secretion of Feds. We discovered that, like in other motile organisms, the FliJ chaperone is required for secretion of flagellar components in general, and that FliS is likely the chaperone for the major flagellin, FlaA. However, FliS and other putative flagellar chaperones are not required for secretion of the Feds. We also discovered that secretion of the Feds occurs during or just after hook biosynthesis, suggesting that construction of a hook is required for maximal secretion of these proteins via the flagellum. In addition, in the absence of the flagellar cap or flagellin glycosylation, we observed an increase in secretion of FedB, CiaI and FspA1, suggesting a possible inverse correlation between the amount of Fed proteins secreted via the flagella and length of the flagellar filament. Furthermore, we have identified N- and C-terminal intramolecular determinants within FedB and CiaI that are required for maximal secretion. Based on how other flagellar proteins are secreted, these findings indicate that a flagellar Type III secretion system (T3SS)-specific signal sequence is likely found at the N-terminus, and that an unidentified chaperone may bind to the C-terminus. Both of these factors appear to be required for maximal flagellar-dependent secretion of the Feds. We also examined the importance of secretion of Feds during commensal… Advisors/Committee Members: Hansen, Eric J., Hendrixson, David R., Alto, Neal, Shiloh, Michael.

Subjects/Keywords: Campylobacter jejuni; Virulence Factors; Flagella

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APA (6^th Edition):

Barrero-Tobon, A. M. (2013). Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/2713

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Barrero-Tobon, Angelica M. “Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni.” 2013. Thesis, University of Texas Southwestern Medical Center. Accessed February 27, 2021. http://hdl.handle.net/2152.5/2713.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Barrero-Tobon, Angelica M. “Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni.” 2013. Web. 27 Feb 2021.

Vancouver:

Barrero-Tobon AM. Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2013. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2152.5/2713.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Barrero-Tobon AM. Identification and Characterization of Flagellar Co-expressed Determinants (Feds) of Campylobacter jejuni. [Thesis]. University of Texas Southwestern Medical Center; 2013. Available from: http://hdl.handle.net/2152.5/2713

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Texas Southwestern Medical Center

21. Balaban, Murat. Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni.

Degree: 2011, University of Texas Southwestern Medical Center

URL: http://hdl.handle.net/2152.5/868

► Campylobacter jejuni is a worldwide leading cause of bacterial gastrointestinal disease. The natural habitat of this organism is the gastrointestinal tracts of warm-blooded animals, especially… (more)

▼ Campylobacter jejuni is a worldwide leading cause of bacterial gastrointestinal disease. The natural habitat of this organism is the gastrointestinal tracts of warm-blooded animals, especially poultry, where the bacterium promotoes a harmless commensal colonization. The abundance of C. jejuni in poultry creates a risk for food-borne infections to human populations. Flagellar motility by C. jejuni is required to colonize both human and animal hosts. For motility, C. jejuni produces amphitrichous flagella, resulting in the formation of a single flagellum at both poles. This work explored factors that regulate numerical and spatial parameters for amphitrichious flagellation. Two factors that have been identified to control flagellar placement and numbers in polarly-flagellated bacteria are the FlhF GTPase and the FlhG ATPase. FlhF has been shown to be required for regulation of flagellar gene expression and flagellar placement in some Pseudomonas and Vibrio species. Characterization of FlhF in C. jejuni was accomplished by creating point mutants in C-terminal GTPase domain of FlhF to decrease its GTPase activity. GTPase mutants, unlike mutants that lack FlhF, did not have a significant reduction in sigma54-dependent flagellar gene expression. Instead, a significant proportion of the population produced flagella at lateral sites or produced multiple flagella at a pole, whereas wild-type bacteria produced single polar flagella. Further experiments suggested that FlhF functions downstream of the FlgSR-flagellar export apparatus (FEA) pathway to activate sigma54-dependent flagellar gene expression. Thus, our data suggested that FlhF and its GTPase activity are required for distinct processes in flagellar gene regulation. FlhG has been shown to control flagellar numbers in Pseudomonas and Vibrio species. We examined flhG mutants and confirmed that FlhG regulates flagellar numbers. C. jejuni flhG mutants also demonstrated a minicell phenotype, which is the result of division erroneously occurring at polar regions. Further examination revealed that FlhG and the flagellar base components compose a novel division inhibition system to spatially prevent polar division and encourage septation at the cellular midpoint for symmetrical division. This work greatly extends our understanding of factors that govern spatial and numerical patterns of polar flagellation and has identified an unprecedented system to spatially regulate division in bacteria. Advisors/Committee Members: Hendrixson, David R..

Subjects/Keywords: Campylobacter jejuni; Cell Division; Flagella

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Balaban, M. (2011). Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni. (Thesis). University of Texas Southwestern Medical Center. Retrieved from http://hdl.handle.net/2152.5/868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Balaban, Murat. “Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni.” 2011. Thesis, University of Texas Southwestern Medical Center. Accessed February 27, 2021. http://hdl.handle.net/2152.5/868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Balaban, Murat. “Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni.” 2011. Web. 27 Feb 2021.

Vancouver:

Balaban M. Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni. [Internet] [Thesis]. University of Texas Southwestern Medical Center; 2011. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2152.5/868.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Balaban M. Determinants Influencing Polar Flagellar Biosynthesis and Cell Division in Campylobacter jejuni. [Thesis]. University of Texas Southwestern Medical Center; 2011. Available from: http://hdl.handle.net/2152.5/868

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Neto, Carlota Duarte Castro. Infeções alimentares por Campylobacter.

Degree: 2017, RCAAP

URL: https://www.rcaap.pt/detail.jsp?id=oai:comum.rcaap.pt:10400.26/20192

►

Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz

Após o isolamento bem-sucedido em fezes na década de… (more)

Subjects/Keywords: Campylobacter; Gastroenterite; Campilobacteriose; Resistência antibiótica

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APA (6^th Edition):

Neto, C. D. C. (2017). Infeções alimentares por Campylobacter. (Thesis). RCAAP. Retrieved from https://www.rcaap.pt/detail.jsp?id=oai:comum.rcaap.pt:10400.26/20192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Neto, Carlota Duarte Castro. “Infeções alimentares por Campylobacter.” 2017. Thesis, RCAAP. Accessed February 27, 2021. https://www.rcaap.pt/detail.jsp?id=oai:comum.rcaap.pt:10400.26/20192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Neto, Carlota Duarte Castro. “Infeções alimentares por Campylobacter.” 2017. Web. 27 Feb 2021.

Vancouver:

Neto CDC. Infeções alimentares por Campylobacter. [Internet] [Thesis]. RCAAP; 2017. [cited 2021 Feb 27]. Available from: https://www.rcaap.pt/detail.jsp?id=oai:comum.rcaap.pt:10400.26/20192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Neto CDC. Infeções alimentares por Campylobacter. [Thesis]. RCAAP; 2017. Available from: https://www.rcaap.pt/detail.jsp?id=oai:comum.rcaap.pt:10400.26/20192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Ottawa

23. Butcher, James. The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni .

Degree: 2015, University of Ottawa

URL: http://hdl.handle.net/10393/32095

► Campylobacter jejuni is one of the most frequent causes of gastroenteritis in both the developing and the developed world. Understanding C. jejuni biology is paramount… (more)

Subjects/Keywords: Fur; Iron; PerR; Campylobacter jejuni

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APA (6^th Edition):

Butcher, J. (2015). The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/32095

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Butcher, James. “The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni .” 2015. Thesis, University of Ottawa. Accessed February 27, 2021. http://hdl.handle.net/10393/32095.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Butcher, James. “The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni .” 2015. Web. 27 Feb 2021.

Vancouver:

Butcher J. The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni . [Internet] [Thesis]. University of Ottawa; 2015. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10393/32095.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Butcher J. The Roles of Iron, Fur and PerR in Regulating Gene Expression in Campylobacter jejuni . [Thesis]. University of Ottawa; 2015. Available from: http://hdl.handle.net/10393/32095

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. Askoura, Momen Mahmoud Ez ElArab Abd ElAziz M. Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract .

Degree: 2015, University of Ottawa

URL: http://hdl.handle.net/10393/32108

► Campylobacter jejuni is a prevalent cause of bacterial gastroenteritis in humans worldwide. The mechanism by which C. jejuni survives stomach acidity remains unknown. In this… (more)

Subjects/Keywords: Campylobacter jejuni; Acid stress

11 more images…

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APA (6^th Edition):

Askoura, M. M. E. E. A. E. M. (2015). Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract . (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/32108

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Askoura, Momen Mahmoud Ez ElArab Abd ElAziz M. “Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract .” 2015. Thesis, University of Ottawa. Accessed February 27, 2021. http://hdl.handle.net/10393/32108.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Askoura, Momen Mahmoud Ez ElArab Abd ElAziz M. “Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract .” 2015. Web. 27 Feb 2021.

Vancouver:

Askoura MMEEAEM. Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract . [Internet] [Thesis]. University of Ottawa; 2015. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10393/32108.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Askoura MMEEAEM. Acid Adaptive Mechanisms of Campylobacter jejuni in the Gastrointestinal Tract . [Thesis]. University of Ottawa; 2015. Available from: http://hdl.handle.net/10393/32108

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

AUT University

25. Sowerby, Niki. Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand .

Degree: AUT University

URL: http://hdl.handle.net/10292/9805

► The Auckland Zoological Park holds 120 species and over 850 animals within a 17-hectare park in central Auckland. Species include non-primate mammals, avians, primates and… (more)

▼ The Auckland Zoological Park holds 120 species and over 850 animals within a 17-hectare park in central Auckland. Species include non-primate mammals, avians, primates and reptiles, including a mixture of exotic and native species. Little is known about the epidemiology of Campylobacter in wildlife populations, as previous and current studies focus on domestic and food producing animals, as well as Campylobacter in medical settings. This study set out to determine and identify Campylobacter in a healthy captive wildlife population and present the isolated organisms virulence potential by investigating the presence of putative virulence genes (flaA, cadF, cdtA, cdtB, cdtC and gyrA). The genes investigated are commonly associated with multifactorial processes that are involved with Campylobacter infection. Based on sequencing profiles of the virulence genes investigated, phylogenetic relationships were demonstrated between the different Campylobacter strains isolated from such a wide variety of animals. Over a 9-month period (December 2013 to August 2014) 202 faecal samples were collected from a variety of animal species of the Auckland Zoo’s captive population, for evaluation of the presence of Campylobacter. From the 202 samples collected, Campylobacter was isolated from 17 (8.9%), where Campylobacter jejuni was the most frequently isolated Campylobacter species, with a recovery rate of 52.9% in the present study. Upon isolation, isolates were then investigated for the presence of specific genes that are commonly associated with pathogenesis of Campylobacter infection. The genes were selected on the basis of their involvement in motility, adhesion, invasion and toxin production, which are all associated with the multifactorial bacterial pathogenic mechanisms. The absence of one of these virulence factors can limit and reduce the organism’s pathogenicity and virulence potential. Of the 6 genes investigated, flagella A (flaA) genes were found in 100%, Campylobacter adhesion factor (cadF) was found in 58.8%, gyrase A (gyrA) in 70.6%, and cytotoxin A, B and C (cdtA, cdtB and cdtC) in 70.6%, 47.1% and 35.3% respectively. Sequencing of these genes revealed both homology and heterogeneity of gene sequences between the different Campylobacter species, demonstrating both genetic conservation and variation respectively. Advisors/Committee Members: Merien, Fabrice (advisor), Vidicki, Miomir (advisor).

Subjects/Keywords: Campylobacter; Wildlife

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APA (6^th Edition):

Sowerby, N. (n.d.). Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand . (Thesis). AUT University. Retrieved from http://hdl.handle.net/10292/9805

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sowerby, Niki. “Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand .” Thesis, AUT University. Accessed February 27, 2021. http://hdl.handle.net/10292/9805.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sowerby, Niki. “Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand .” Web. 27 Feb 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Sowerby N. Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand . [Internet] [Thesis]. AUT University; [cited 2021 Feb 27]. Available from: http://hdl.handle.net/10292/9805.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

Sowerby N. Identification and genotyping of Campylobacter spp. strains isolated from a captive wildlife population in New Zealand . [Thesis]. AUT University; Available from: http://hdl.handle.net/10292/9805

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Iowa State University

26. Grinnage-Pulley, Tara Leigh. Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni.

Degree: 2013, Iowa State University

URL: https://lib.dr.iastate.edu/etd/13495

► Campylobacter jejuni is a zoonotic, foodborne pathogen causing gastroenteritis in humans. The multidrug efflux pump CmeABC plays a key role in antimicrobial resistance by extruding… (more)

▼ Campylobacter jejuni is a zoonotic, foodborne pathogen causing gastroenteritis in humans. The multidrug efflux pump CmeABC plays a key role in antimicrobial resistance by extruding structurally diverse compounds and is essential for intestinal colonization by mediating bile resistance. Expression of cmeABC is under the control of CmeR, a TetR family transcriptional regulator, and CosR, an oxidative stress response regulator. However, the molecular basis and functional consequences of differential CmeABC expression as well as the interactive role of CosR and CmeR in modulating cmeABC expression are still unknown. To address these questions, we performed two sets of studies. In the first study, we evaluated differential expression of cmeABC in naturally occurring C. jejuni isolates and identified the mutations associated with overexpression of cmeABC. It was found that 67% of examined C. jejuni isolates exhibited a CmeABC-overexpressed phenotype as determined by immunoblotting and real-time RT-PCR. This phenotype was further linked to mutations in the cmeABC promoter sequence that decreased the binding of CmeR to the promoter DNA or a reduced cmeR expression. Consequently, both types of mutation increased expression of cmeABC. Additionally, the CmeABC-overexpressed phenotype was associated with increased emergence of ciprofloxacin-resistant mutants in cultures treated with a fluoroquinolone antibiotic. In the second study, we demonstrated that CmeR and CosR simultaneously bound to two separate sites in the cmeABC promoter, providing dual repression of cmeABC expression. The two regulators interact with the cmeABC promoter independently, but maximal repression by CmeR and CosR requires a 17 bp spacer between the binding sites as shortening the spacer interferes with CmeR binding of the promoter in the presence of CosR. Additionally, we demonstrated that CosR utilizes the single cysteine residue (C218) to sense oxidative stress as oxidation of C218 inhibited CosR binding to the promoter, providing a mechanistic explanation for oxidative-stress-induced, CosR-mediated overexpression of cmeABC. Together, these results reveal sophisticated mechanisms that modulate expression of cmeABC and identify a new signal (oxidative stress) that interacts with this efflux system. Considering the important role of CmeABC in Campylobacter pathobiology, the diverse mechanisms influencing cmeABC expression may facilitate Campylobacter adaptation to diverse environmental conditions.

Subjects/Keywords: Campylobacter; Efflux pump; Microbiology

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APA (6^th Edition):

Grinnage-Pulley, T. L. (2013). Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. (Thesis). Iowa State University. Retrieved from https://lib.dr.iastate.edu/etd/13495

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Grinnage-Pulley, Tara Leigh. “Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni.” 2013. Thesis, Iowa State University. Accessed February 27, 2021. https://lib.dr.iastate.edu/etd/13495.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Grinnage-Pulley, Tara Leigh. “Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni.” 2013. Web. 27 Feb 2021.

Vancouver:

Grinnage-Pulley TL. Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. [Internet] [Thesis]. Iowa State University; 2013. [cited 2021 Feb 27]. Available from: https://lib.dr.iastate.edu/etd/13495.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Grinnage-Pulley TL. Regulatory and mutational mechanisms for differential expression of the CmeABC multidrug efflux pump in Campylobacter jejuni. [Thesis]. Iowa State University; 2013. Available from: https://lib.dr.iastate.edu/etd/13495

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana State University

27. May, Lewis K. The microaerophilic nature of Vibrio Fetus.

Degree: MS, College of Agriculture, 1953, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/5715

Subjects/Keywords: Campylobacter fetus.

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APA (6^th Edition):

May, L. K. (1953). The microaerophilic nature of Vibrio Fetus. (Masters Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5715

Chicago Manual of Style (16^th Edition):

May, Lewis K. “The microaerophilic nature of Vibrio Fetus.” 1953. Masters Thesis, Montana State University. Accessed February 27, 2021. https://scholarworks.montana.edu/xmlui/handle/1/5715.

MLA Handbook (7^th Edition):

May, Lewis K. “The microaerophilic nature of Vibrio Fetus.” 1953. Web. 27 Feb 2021.

Vancouver:

May LK. The microaerophilic nature of Vibrio Fetus. [Internet] [Masters thesis]. Montana State University; 1953. [cited 2021 Feb 27]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5715.

Council of Science Editors:

May LK. The microaerophilic nature of Vibrio Fetus. [Masters Thesis]. Montana State University; 1953. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5715

Montana State University

28. Alexander, James Kermott. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.

Degree: MS, College of Agriculture, 1954, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/4737

Subjects/Keywords: Campylobacter fetus.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Alexander, J. K. (1954). The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. (Masters Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/4737

Chicago Manual of Style (16^th Edition):

Alexander, James Kermott. “The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.” 1954. Masters Thesis, Montana State University. Accessed February 27, 2021. https://scholarworks.montana.edu/xmlui/handle/1/4737.

MLA Handbook (7^th Edition):

Alexander, James Kermott. “The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus.” 1954. Web. 27 Feb 2021.

Vancouver:

Alexander JK. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. [Internet] [Masters thesis]. Montana State University; 1954. [cited 2021 Feb 27]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4737.

Council of Science Editors:

Alexander JK. The utilization of carbohydrate intermediates and amino acids by Vibrio Fetus. [Masters Thesis]. Montana State University; 1954. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4737

University of Illinois – Urbana-Champaign

29. Berquist, Allison. Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens.

Degree: MS, 0037, 2014, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/50374

► Campylobacter jejuni is one of the leading causes of foodborne bacterial illness in the world. The majority of cases of campylobacteriosis are associated with the… (more)

▼ Campylobacter jejuni is one of the leading causes of foodborne bacterial illness in the world. The majority of cases of campylobacteriosis are associated with the consumption of raw or undercooked poultry meat or their cross-contamination with other food products. Strategies to reduce the presence of Campylobacter in the poultry supply are underdeveloped. The probiotic Lactobacillus spp. are a viable delivery vehicle for mucosal vaccines due to the Generally Recognized As Safe (GRAS) status. In addition, recombinant lactobacilli present proteins to the mucosal surface and elicit host immune responses. The overall objectives of this research were to 1) colonize broiler chickens with C. jejuni; 2) construct recombinant Lactobacillus for oral delivery of vaccines against C. jejuni; and 3) evaluate the immunogenicity of the recombinant Lactobacillus strains in broiler chickens. To meet these objectives, broiler chickens were orally administered with 109 CFU/mL of C. jejuni NCTC 11168 on d 14, then necropsied on d 21 for direct-plating of the cecal contents. Results indicate successful C. jejuni colonization of the cecal crypts. Lactobacillus strains were engineered to express C. jejuni FlpA Domain II under a promoter fused to a secretion signal with or without an anchoring signal from the mucus-binding protein of Lactobacillus acidophilus NCFM. Additional work must be conducted to evaluate the exterior protein expression and in vivo antigen-immune response within broiler chickens. If successful, the recombinant Lactobacillus strain could be an attractive candidate as a food-grade live vaccine against Campylobacter colonization. In addition, a non-genetically modified delivery approach proposes attachment of C. jejuni FlpA to the cell wall of lactobacilli utilizing one of three cell wall binding domains. Reduction of Campylobacter at the poultry farm decreases the introduction of the bacteria into the retail market and decreases the incidence of campylobacteriosis. Advisors/Committee Members: Miller, Michael J. (advisor).

Subjects/Keywords: Campylobacter; Lactobacillus; probiotic; vaccine; chicken

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Berquist, A. (2014). Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/50374

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Berquist, Allison. “Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens.” 2014. Thesis, University of Illinois – Urbana-Champaign. Accessed February 27, 2021. http://hdl.handle.net/2142/50374.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Berquist, Allison. “Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens.” 2014. Web. 27 Feb 2021.

Vancouver:

Berquist A. Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2014. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2142/50374.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Berquist A. Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens. [Thesis]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/50374

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

30. Wooten, Jessica Michelle. The coaggregative abilities of lactobacilli and Campylobacter jejuni.

Degree: MS, Food Science & Human Nutrition, 2015, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/89236

► Campylobacter jejuni is a pathogen commonly found in poultry that is one of the main bacterial causes of foodborne diarrheal disease in humans. The aim… (more)

Subjects/Keywords: Lactobacillus; Campylobacter jejuni; coaggregation

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wooten, J. M. (2015). The coaggregative abilities of lactobacilli and Campylobacter jejuni. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89236

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wooten, Jessica Michelle. “The coaggregative abilities of lactobacilli and Campylobacter jejuni.” 2015. Thesis, University of Illinois – Urbana-Champaign. Accessed February 27, 2021. http://hdl.handle.net/2142/89236.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wooten, Jessica Michelle. “The coaggregative abilities of lactobacilli and Campylobacter jejuni.” 2015. Web. 27 Feb 2021.

Vancouver:

Wooten JM. The coaggregative abilities of lactobacilli and Campylobacter jejuni. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2015. [cited 2021 Feb 27]. Available from: http://hdl.handle.net/2142/89236.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wooten JM. The coaggregative abilities of lactobacilli and Campylobacter jejuni. [Thesis]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89236

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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