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You searched for subject:(CYP3A4). Showing records 1 – 30 of 53 total matches.

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North Carolina State University

1. Croom, Edward Lee. Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos.

Degree: PhD, Toxicology, 2010, North Carolina State University

 CROOM, EDWARD LEE. Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos. (Under the direction of Dr. Ernest Hodgson and the… (more)

Subjects/Keywords: bioactivation; chlorpyrifos; CYP2B6; CYP3A4; developmental expression

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Croom, E. L. (2010). Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos. (Doctoral Dissertation). North Carolina State University. Retrieved from http://www.lib.ncsu.edu/resolver/1840.16/6156

Chicago Manual of Style (16th Edition):

Croom, Edward Lee. “Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos.” 2010. Doctoral Dissertation, North Carolina State University. Accessed January 18, 2021. http://www.lib.ncsu.edu/resolver/1840.16/6156.

MLA Handbook (7th Edition):

Croom, Edward Lee. “Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos.” 2010. Web. 18 Jan 2021.

Vancouver:

Croom EL. Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos. [Internet] [Doctoral dissertation]. North Carolina State University; 2010. [cited 2021 Jan 18]. Available from: http://www.lib.ncsu.edu/resolver/1840.16/6156.

Council of Science Editors:

Croom EL. Human Hepatic Expression of CYP2B6: Developmental Pattern and In Vitro Bioactivation of Chlorpyrifos. [Doctoral Dissertation]. North Carolina State University; 2010. Available from: http://www.lib.ncsu.edu/resolver/1840.16/6156


University of Illinois – Chicago

2. Zhang, Shu. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.

Degree: 2016, University of Illinois – Chicago

 Small heterodimer partner (SHP) is a transcriptional corepressor of a number of ligand regulated nuclear receptors (NR) and orphan receptors, and represses their target genes… (more)

Subjects/Keywords: Cytochrome P450; CYP3A4; CYP2D6; FXR; ATRA

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APA (6th Edition):

Zhang, S. (2016). Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21572

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Thesis, University of Illinois – Chicago. Accessed January 18, 2021. http://hdl.handle.net/10027/21572.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Web. 18 Jan 2021.

Vancouver:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Internet] [Thesis]. University of Illinois – Chicago; 2016. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10027/21572.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Thesis]. University of Illinois – Chicago; 2016. Available from: http://hdl.handle.net/10027/21572

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Chicago

3. Zhang, Shu. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.

Degree: 2016, University of Illinois – Chicago

 Small heterodimer partner (SHP) is a transcriptional corepressor of a number of ligand regulated nuclear receptors (NR) and orphan receptors, and represses their target genes… (more)

Subjects/Keywords: Cytochrome P450; CYP3A4; CYP2D6; FXR; ATRA

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APA (6th Edition):

Zhang, S. (2016). Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21629

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Thesis, University of Illinois – Chicago. Accessed January 18, 2021. http://hdl.handle.net/10027/21629.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Web. 18 Jan 2021.

Vancouver:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Internet] [Thesis]. University of Illinois – Chicago; 2016. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10027/21629.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Thesis]. University of Illinois – Chicago; 2016. Available from: http://hdl.handle.net/10027/21629

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Chicago

4. Zhang, Shu. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.

Degree: 2016, University of Illinois – Chicago

 Small heterodimer partner (SHP) is a transcriptional corepressor of a number of ligand regulated nuclear receptors (NR) and orphan receptors, and represses their target genes… (more)

Subjects/Keywords: Cytochrome P450; CYP3A4; CYP2D6; FXR; ATRA

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APA (6th Edition):

Zhang, S. (2016). Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21630

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Thesis, University of Illinois – Chicago. Accessed January 18, 2021. http://hdl.handle.net/10027/21630.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Zhang, Shu. “Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner.” 2016. Web. 18 Jan 2021.

Vancouver:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Internet] [Thesis]. University of Illinois – Chicago; 2016. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10027/21630.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zhang S. Transcriptional Regulation of CYP3A4 and CYP2D6 by Small Heterodimer Partner. [Thesis]. University of Illinois – Chicago; 2016. Available from: http://hdl.handle.net/10027/21630

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Willrich, Maria Alice Vieira. Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo.

Degree: PhD, Análises Clínicas, 2011, University of São Paulo

 Introdução: As CYP3A4 e CYP3A5 são enzimas do citocromo P450 responsáveis pela biotransformação de esteróides endógenos e vários fármacos, entre eles as estatinas. Polimorfismos nos… (more)

Subjects/Keywords: CYP3A4; CYP3A4; CYP3A5; CYP3A5; Estatinas; Expressão gênica; Ezetimiba; Ezetimibe; Farmacogenômica; Gene expression; Pharmacogenomics; Statins

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APA (6th Edition):

Willrich, M. A. V. (2011). Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/9/9136/tde-12092012-150610/ ;

Chicago Manual of Style (16th Edition):

Willrich, Maria Alice Vieira. “Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo.” 2011. Doctoral Dissertation, University of São Paulo. Accessed January 18, 2021. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-12092012-150610/ ;.

MLA Handbook (7th Edition):

Willrich, Maria Alice Vieira. “Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo.” 2011. Web. 18 Jan 2021.

Vancouver:

Willrich MAV. Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Jan 18]. Available from: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-12092012-150610/ ;.

Council of Science Editors:

Willrich MAV. Efeitos de hipolipemiantes sobre a expressão de CYP3A4 e CYP3A5 in vitro e in vivo. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/9/9136/tde-12092012-150610/ ;

6. Michaut, Anaïs. Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity.

Degree: Docteur es, Biologie et sciences de la santé, 2015, Rennes 1

 L'obésité et les maladies du foie associées (NAFLD) augmentent le risque et la sévérité de l’hépatotoxicité induite par certains xénobiotiques, mais les mécanismes impliqués sont… (more)

Subjects/Keywords: Obésité; Stéatose; Nafld; Paracétamol; Cyp2e1; Cyp3a4; Acide gras; HepaRG; Obésity; Steatosis; Nafld; Acetaminophen; Cyp2e1; Cyp3a4; Fatty acid; HepaRG

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APA (6th Edition):

Michaut, A. (2015). Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity. (Doctoral Dissertation). Rennes 1. Retrieved from http://www.theses.fr/2015REN1B015

Chicago Manual of Style (16th Edition):

Michaut, Anaïs. “Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity.” 2015. Doctoral Dissertation, Rennes 1. Accessed January 18, 2021. http://www.theses.fr/2015REN1B015.

MLA Handbook (7th Edition):

Michaut, Anaïs. “Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity.” 2015. Web. 18 Jan 2021.

Vancouver:

Michaut A. Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity. [Internet] [Doctoral dissertation]. Rennes 1; 2015. [cited 2021 Jan 18]. Available from: http://www.theses.fr/2015REN1B015.

Council of Science Editors:

Michaut A. Mise au point d'un modèle de stéatose hépatique liée à l'obésité : application à l'étude de la toxicité du paracétamol : Development of e cell model of liver steatosis related to obesity : application to the study of acetaminophen toxicity. [Doctoral Dissertation]. Rennes 1; 2015. Available from: http://www.theses.fr/2015REN1B015


Vilnius University

7. Dapkūnas, Justas. Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas.

Degree: PhD, Biochemistry, 2011, Vilnius University

Pagrindinis šio darbo tikslas buvo kiekybinio struktūros ir aktyvumo ryšio modelių, prognozuojančių su vaistų metabolizmu susijusias savybes, kūrimas. Modeliai, prognozuojantys CYP3A4 slopinimą ir žmogaus kepenų… (more)

Subjects/Keywords: Citochromai P450; QSAR; CYP3A4 slopinimas; Vaistų metabolizmas; Regioselektyvumo progozavimas; Cytochrome P450; QSAR; CYP3A4 inhibition; Drug metabolism; Regioselectivity prediction

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APA (6th Edition):

Dapkūnas, J. (2011). Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114342-83717 ;

Chicago Manual of Style (16th Edition):

Dapkūnas, Justas. “Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas.” 2011. Doctoral Dissertation, Vilnius University. Accessed January 18, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114342-83717 ;.

MLA Handbook (7th Edition):

Dapkūnas, Justas. “Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas.” 2011. Web. 18 Jan 2021.

Vancouver:

Dapkūnas J. Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas. [Internet] [Doctoral dissertation]. Vilnius University; 2011. [cited 2021 Jan 18]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114342-83717 ;.

Council of Science Editors:

Dapkūnas J. Citochromų P450 katalizuojamo vaistų metabolizmo kompiuterinis modeliavimas. [Doctoral Dissertation]. Vilnius University; 2011. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114342-83717 ;


Vilnius University

8. Dapkūnas, Justas. Computational modeling of cytochrome P450-mediated drug metabolism.

Degree: Dissertation, Biochemistry, 2011, Vilnius University

The main objective of this study was the development of QSAR models for drug metabolism-related properties. Novel GALAS (Global, Adjusted Locally According to Similarity) modeling… (more)

Subjects/Keywords: Cytochrome P450; QSAR; CYP3A4 inhibition; Drug metabolism; Regioselectivity prediction; Citochromai P450; QSAR; CYP3A4 slopinimas; Vaistų metabolizmas; Regioselektyvumo prognozavimas

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APA (6th Edition):

Dapkūnas, J. (2011). Computational modeling of cytochrome P450-mediated drug metabolism. (Doctoral Dissertation). Vilnius University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114651-54627 ;

Chicago Manual of Style (16th Edition):

Dapkūnas, Justas. “Computational modeling of cytochrome P450-mediated drug metabolism.” 2011. Doctoral Dissertation, Vilnius University. Accessed January 18, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114651-54627 ;.

MLA Handbook (7th Edition):

Dapkūnas, Justas. “Computational modeling of cytochrome P450-mediated drug metabolism.” 2011. Web. 18 Jan 2021.

Vancouver:

Dapkūnas J. Computational modeling of cytochrome P450-mediated drug metabolism. [Internet] [Doctoral dissertation]. Vilnius University; 2011. [cited 2021 Jan 18]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114651-54627 ;.

Council of Science Editors:

Dapkūnas J. Computational modeling of cytochrome P450-mediated drug metabolism. [Doctoral Dissertation]. Vilnius University; 2011. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20111003_114651-54627 ;

9. Bory, Sothavireak. Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation.

Degree: Docteur es, Pathologie humaine, 2010, Aix-Marseille 2

La mise au point et la validation d’une méthode de dosage par CLHP des alcaloïdes majoritaires (cépharanthine,xylopinine, tétrahydropalmatine) de Stephania rotunda sont réalisées. La méthode… (more)

Subjects/Keywords: Stephania rotunda Lour.; Alcaloïdes; Cépharantine; Métabolisme in vitro; Chlp; Cyp3a4

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APA (6th Edition):

Bory, S. (2010). Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation. (Doctoral Dissertation). Aix-Marseille 2. Retrieved from http://www.theses.fr/2010AIX22960

Chicago Manual of Style (16th Edition):

Bory, Sothavireak. “Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation.” 2010. Doctoral Dissertation, Aix-Marseille 2. Accessed January 18, 2021. http://www.theses.fr/2010AIX22960.

MLA Handbook (7th Edition):

Bory, Sothavireak. “Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation.” 2010. Web. 18 Jan 2021.

Vancouver:

Bory S. Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation. [Internet] [Doctoral dissertation]. Aix-Marseille 2; 2010. [cited 2021 Jan 18]. Available from: http://www.theses.fr/2010AIX22960.

Council of Science Editors:

Bory S. Étude ethnopharmacologique d'une plante utilisée en médecine traditionnelle cambodgienne dans le traitement de la malaria : stephania rotunda (Lour.) : approche analytique, phytochimique, pharmacologique et métabolique : Ethnopharmacological study of cambodian medicinal plant used traditionally in malaria treatment : stephania rotunda (Lour.) : analytical, phytochemical, pharmacological and metabolic investigation. [Doctoral Dissertation]. Aix-Marseille 2; 2010. Available from: http://www.theses.fr/2010AIX22960

10. Gratien-Debette, Marilyne. Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation.

Degree: Docteur es, Pharmacologie, 2015, Limoges

La transplantation hépatique est une technique chirurgicale maîtrisée, mais le devenir à long terme du greffon et de l’hôte doit encore être amélioré. L’étude pharmacogénétique… (more)

Subjects/Keywords: Transplantation hépatique; CYP3A4*22; CYP3A5; ABCB1; Perte du greffon; Rejet chronique; Néphrotoxicité; Liver transplantation; CYP3A4*22; CYP3A5; ABCB1; Graft loss; Chronic rejection; Nephrotoxicity; 617.95

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APA (6th Edition):

Gratien-Debette, M. (2015). Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation. (Doctoral Dissertation). Limoges. Retrieved from http://www.theses.fr/2015LIMO0032

Chicago Manual of Style (16th Edition):

Gratien-Debette, Marilyne. “Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation.” 2015. Doctoral Dissertation, Limoges. Accessed January 18, 2021. http://www.theses.fr/2015LIMO0032.

MLA Handbook (7th Edition):

Gratien-Debette, Marilyne. “Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation.” 2015. Web. 18 Jan 2021.

Vancouver:

Gratien-Debette M. Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation. [Internet] [Doctoral dissertation]. Limoges; 2015. [cited 2021 Jan 18]. Available from: http://www.theses.fr/2015LIMO0032.

Council of Science Editors:

Gratien-Debette M. Etude rétrospective de l'influence des polymorphismes génétiques de CYP3A4, CYP3A5 et ABCB1 des donneurs et des receveurs sur les effets des immunosuppresseurs en transplantation hépatique : Retrospective study on influence of donor and recipient CYP3A4, CYP3A5 and ABCB1 genotypes on anticalcineurin therapy effect in liver transplantation. [Doctoral Dissertation]. Limoges; 2015. Available from: http://www.theses.fr/2015LIMO0032

11. Paolini, Marion. Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments.

Degree: Docteur es, Recherche clinique, innovation technologique, santé publique, 2017, Université Paris-Saclay (ComUE)

Les différences de réponse médicamenteuse entre patients sont fréquentes, conduisant souvent à des difficultés à cibler la fenêtre thérapeutique et optimiser le traitement. Les médicaments… (more)

Subjects/Keywords: Nanomédecine; Inhibition du CYP3A4; Pharmacocinétique; Ciblage des hépatocytes; Furanocoumarine; Carcinome hépatocellulaire différencié; Nanomedicine; CYP3A4 inhibition; Pharmacoenhancer; Hepatocyte targeting; Furanocoumarin; Differentiated hepatocellular carcinoma

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APA (6th Edition):

Paolini, M. (2017). Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments. (Doctoral Dissertation). Université Paris-Saclay (ComUE). Retrieved from http://www.theses.fr/2017SACLS095

Chicago Manual of Style (16th Edition):

Paolini, Marion. “Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments.” 2017. Doctoral Dissertation, Université Paris-Saclay (ComUE). Accessed January 18, 2021. http://www.theses.fr/2017SACLS095.

MLA Handbook (7th Edition):

Paolini, Marion. “Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments.” 2017. Web. 18 Jan 2021.

Vancouver:

Paolini M. Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments. [Internet] [Doctoral dissertation]. Université Paris-Saclay (ComUE); 2017. [cited 2021 Jan 18]. Available from: http://www.theses.fr/2017SACLS095.

Council of Science Editors:

Paolini M. Nouvelles compositions pour l'administration d'agents thérapeutiques : Apport de la nanomédecine pour l'optimisation du ratio bénéfice-risque du traitement : New Compositions for the Administration of Therapeutic Agents : Nanomedicine as a Means to Optimise the Benefit-Risk Ratio of Treatments. [Doctoral Dissertation]. Université Paris-Saclay (ComUE); 2017. Available from: http://www.theses.fr/2017SACLS095

12. Gassiot, Matthieu. Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors.

Degree: Docteur es, Biologie Santé, 2017, Montpellier

 De plus en plus d’inhibiteurs de kinase (IKs) sont testés dans le cancer de la prostate qui représente chez l’homme un enjeu de santé publique… (more)

Subjects/Keywords: Inhibiteurs de kinase; Pxr; Cancer de la prostate; Combinaisons anti-BRAF-Anti-MEK; Cyp3a4; Abcb1; Kinase inhibitors; Pxr; Prostate cancer; Anti-BRAF-Anti-MEK associations; Cyp3a4; Abcb1

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APA (6th Edition):

Gassiot, M. (2017). Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors. (Doctoral Dissertation). Montpellier. Retrieved from http://www.theses.fr/2017MONTT133

Chicago Manual of Style (16th Edition):

Gassiot, Matthieu. “Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors.” 2017. Doctoral Dissertation, Montpellier. Accessed January 18, 2021. http://www.theses.fr/2017MONTT133.

MLA Handbook (7th Edition):

Gassiot, Matthieu. “Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors.” 2017. Web. 18 Jan 2021.

Vancouver:

Gassiot M. Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors. [Internet] [Doctoral dissertation]. Montpellier; 2017. [cited 2021 Jan 18]. Available from: http://www.theses.fr/2017MONTT133.

Council of Science Editors:

Gassiot M. Rôle du récepteur des xénobiotiques PXR (Pregnane X Receptor) et de ses gènes cibles sur la sensibilité des lignées de cancer de prostate aux inhibiteurs de kinases : Role of the xenobiotic receptor PXR (Pregnane X Receptor) and its target genes on the sensitivity of prostate cancer lines to Kinase Inhibitors. [Doctoral Dissertation]. Montpellier; 2017. Available from: http://www.theses.fr/2017MONTT133


University of Helsinki

13. Koskela, Outi. CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla.

Degree: Farmaceutiska fakulteten, 2012, University of Helsinki

 Farmakogenetiikka on tieteenala, joka tutkii geneettisten erojen vaikusta lääkeaineiden vasteeseen eli farmakokinetiikkaan, tehoon ja haittavaikutuksiin. Kirjallisuuskatsaus käsittelee kipulääkkeiden farmakogenetiikkaa. Tutkituimmat kipulääkkeiden vastetta muuntavat geenivariaatiot ovat… (more)

Subjects/Keywords: CYP2D6; CYP3A4; CYP3A5; SNP; pharmacogenetics; analgesics; genetic polymorphism; kipulääkkeet; geneettinen polymorfia; farmakogenetiikka; Farmakologi; Pharmacology; Farmakologia

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APA (6th Edition):

Koskela, O. (2012). CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla. (Masters Thesis). University of Helsinki. Retrieved from http://hdl.handle.net/10138/37552

Chicago Manual of Style (16th Edition):

Koskela, Outi. “CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla.” 2012. Masters Thesis, University of Helsinki. Accessed January 18, 2021. http://hdl.handle.net/10138/37552.

MLA Handbook (7th Edition):

Koskela, Outi. “CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla.” 2012. Web. 18 Jan 2021.

Vancouver:

Koskela O. CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla. [Internet] [Masters thesis]. University of Helsinki; 2012. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10138/37552.

Council of Science Editors:

Koskela O. CYP2D6-, CYP3A4- ja CYP3A5-entsyymien geneettinen polymorfia rintasyöpäpotilailla. [Masters Thesis]. University of Helsinki; 2012. Available from: http://hdl.handle.net/10138/37552


University of Washington

14. Wahlin, Michelle Diane. Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity.

Degree: PhD, 2014, University of Washington

 Lapatinib was the first orally active dual tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR, ErbB1) and human epidermal receptor 2 (HER2,… (more)

Subjects/Keywords: bioactivation; CYP3A4; CYP3A5; hepatotoxicity; lapatinib; metabolism; Pharmaceutical sciences; Chemistry; Toxicology; medicinal chemistry

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APA (6th Edition):

Wahlin, M. D. (2014). Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity. (Doctoral Dissertation). University of Washington. Retrieved from http://hdl.handle.net/1773/26061

Chicago Manual of Style (16th Edition):

Wahlin, Michelle Diane. “Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity.” 2014. Doctoral Dissertation, University of Washington. Accessed January 18, 2021. http://hdl.handle.net/1773/26061.

MLA Handbook (7th Edition):

Wahlin, Michelle Diane. “Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity.” 2014. Web. 18 Jan 2021.

Vancouver:

Wahlin MD. Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity. [Internet] [Doctoral dissertation]. University of Washington; 2014. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/1773/26061.

Council of Science Editors:

Wahlin MD. Defining the Relationship between the Bioactivation of Lapatinib by CYP3A and Lapatinib-Induced Hepatotoxicity. [Doctoral Dissertation]. University of Washington; 2014. Available from: http://hdl.handle.net/1773/26061


Universidade do Rio Grande do Sul

15. Antunes, Marina Venzon. Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama.

Degree: 2014, Universidade do Rio Grande do Sul

 Introdução: a ação antiestrogênica do tamoxifeno (TAM) é dependente da bioativação à endoxifeno (EDF) e 4-hidroxitamoxifeno (HTF). É bastante provável que sua eficácia terapêutica esteja… (more)

Subjects/Keywords: Tamoxifeno; Tamoxifen; Citocromo P-450 CYP2D6; Endoxifen; Vitamina D; 4-hydroxytamoxifen; CYP2D6; Neoplasias da mama; CYP3A4; DBS; Vitamin D

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APA (6th Edition):

Antunes, M. V. (2014). Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/110238

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Antunes, Marina Venzon. “Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama.” 2014. Thesis, Universidade do Rio Grande do Sul. Accessed January 18, 2021. http://hdl.handle.net/10183/110238.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Antunes, Marina Venzon. “Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama.” 2014. Web. 18 Jan 2021.

Vancouver:

Antunes MV. Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2014. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10183/110238.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Antunes MV. Influência de fatores genéticos e ambientais na atividade da CYP2D6 e CYP3A4 e sua relação com a bioativação do tamoxifeno em pacientes com câncer de mama. [Thesis]. Universidade do Rio Grande do Sul; 2014. Available from: http://hdl.handle.net/10183/110238

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Michigan

16. Dhaini, Hassan R. Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma.

Degree: PhD, Toxicology, 2002, University of Michigan

 Osteosarcoma is a primary malignancy of bone with a tendeney for early pulmonary metastasis. There is a need to identify patients who may benefit from… (more)

Subjects/Keywords: Cyp3a4/5; Cytochrome P450; Factor; New; Osteosarcoma; Prognostic

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APA (6th Edition):

Dhaini, H. R. (2002). Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/131733

Chicago Manual of Style (16th Edition):

Dhaini, Hassan R. “Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma.” 2002. Doctoral Dissertation, University of Michigan. Accessed January 18, 2021. http://hdl.handle.net/2027.42/131733.

MLA Handbook (7th Edition):

Dhaini, Hassan R. “Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma.” 2002. Web. 18 Jan 2021.

Vancouver:

Dhaini HR. Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma. [Internet] [Doctoral dissertation]. University of Michigan; 2002. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2027.42/131733.

Council of Science Editors:

Dhaini HR. Cytochrome P450 CYP3A4 /5: A new prognostic factor for osteosarcoma. [Doctoral Dissertation]. University of Michigan; 2002. Available from: http://hdl.handle.net/2027.42/131733

17. Olivares Morales, Andres. Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.

Degree: 2016, University of Manchester

 The majority of drugs available on the market are intended to be administered through the oral route. To achieve the desired therapeutic effect, an orally… (more)

Subjects/Keywords: Oral bioavailability; physiologically-based pharmacokinetics (PBPK); prediction; modelling and simulation; oxybutynin; CYP3A4; pre-clinical species; gastrointestinal; first pass metabolism; models

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APA (6th Edition):

Olivares Morales, A. (2016). Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300858

Chicago Manual of Style (16th Edition):

Olivares Morales, Andres. “Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.” 2016. Doctoral Dissertation, University of Manchester. Accessed January 18, 2021. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300858.

MLA Handbook (7th Edition):

Olivares Morales, Andres. “Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.” 2016. Web. 18 Jan 2021.

Vancouver:

Olivares Morales A. Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2021 Jan 18]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300858.

Council of Science Editors:

Olivares Morales A. Prediction of oral drug bioavailability: from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. [Doctoral Dissertation]. University of Manchester; 2016. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:300858


Université de Montréal

18. Michaud, Véronique. L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5.

Degree: 2004, Université de Montréal

Subjects/Keywords: Cytochromes P450; CYP3A4; CYP3A5; Dompéridone; Métabolisme; Variabilité interindividuelle

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APA (6th Edition):

Michaud, V. (2004). L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5. (Thesis). Université de Montréal. Retrieved from http://hdl.handle.net/1866/14423

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Michaud, Véronique. “L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5.” 2004. Thesis, Université de Montréal. Accessed January 18, 2021. http://hdl.handle.net/1866/14423.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Michaud, Véronique. “L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5.” 2004. Web. 18 Jan 2021.

Vancouver:

Michaud V. L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5. [Internet] [Thesis]. Université de Montréal; 2004. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/1866/14423.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Michaud V. L'utilisation de la dompéridone comme substrat marqueur de l'activité in vitro des CYP3A4 et CYP3A5. [Thesis]. Université de Montréal; 2004. Available from: http://hdl.handle.net/1866/14423

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of California – Irvine

19. Samuels, Eric Ray. A Tale of Two Cities: Merging Biology with Chemistry for Drug Design.

Degree: Pharmacological Sciences, 2018, University of California – Irvine

 PART IThe amidohydrolase urease is critical for the survival and pathogenesis of Helicobacter pylori. Urease catalyzes the hydrolysis of one molecule of urea to two… (more)

Subjects/Keywords: Pharmaceutical sciences; Organic chemistry; Biochemistry; CYP3A4; Helicobacter pylori; High Throughput Screening; Ritonavir; Structure based drug design; Urease

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APA (6th Edition):

Samuels, E. R. (2018). A Tale of Two Cities: Merging Biology with Chemistry for Drug Design. (Thesis). University of California – Irvine. Retrieved from http://www.escholarship.org/uc/item/18z7407c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Samuels, Eric Ray. “A Tale of Two Cities: Merging Biology with Chemistry for Drug Design.” 2018. Thesis, University of California – Irvine. Accessed January 18, 2021. http://www.escholarship.org/uc/item/18z7407c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Samuels, Eric Ray. “A Tale of Two Cities: Merging Biology with Chemistry for Drug Design.” 2018. Web. 18 Jan 2021.

Vancouver:

Samuels ER. A Tale of Two Cities: Merging Biology with Chemistry for Drug Design. [Internet] [Thesis]. University of California – Irvine; 2018. [cited 2021 Jan 18]. Available from: http://www.escholarship.org/uc/item/18z7407c.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Samuels ER. A Tale of Two Cities: Merging Biology with Chemistry for Drug Design. [Thesis]. University of California – Irvine; 2018. Available from: http://www.escholarship.org/uc/item/18z7407c

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


North-West University

20. Calitz, Carlemi. Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz .

Degree: 2014, North-West University

 Patients on anti-retroviral (ARV) drug treatment are sometimes simultaneously taking other prescribed drugs and/or over-the-counter drugs and/or herbal remedies. Pharmacokinetic drug-drug or herb-drug interactions can… (more)

Subjects/Keywords: Herb-drug interactions; Efflux; P-glycoprotein; CYP3A4; Caco-2; LS180; Metabolism; Kruie-geneesmiddel interaksies; P-glikoproteien; Metabolisme

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APA (6th Edition):

Calitz, C. (2014). Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz . (Thesis). North-West University. Retrieved from http://hdl.handle.net/10394/14481

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Calitz, Carlemi. “Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz .” 2014. Thesis, North-West University. Accessed January 18, 2021. http://hdl.handle.net/10394/14481.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Calitz, Carlemi. “Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz .” 2014. Web. 18 Jan 2021.

Vancouver:

Calitz C. Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz . [Internet] [Thesis]. North-West University; 2014. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10394/14481.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Calitz C. Impact of selected herbal products on intestinal epithelial permeation and metabolism of indinavir / Carlemi Calitz . [Thesis]. North-West University; 2014. Available from: http://hdl.handle.net/10394/14481

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Freie Universität Berlin

21. Stoffels, Felix. Polymorphisms in the promoter and enhancer region of CYP3A4.

Degree: 2010, Freie Universität Berlin

 In this study the activity of CYP3A4 was measured at 104 healthy european subjects by the degradation of alprazolam through the enzyme before and after… (more)

Subjects/Keywords: CYP3A4; promoter; enhancer; polymorphism; alprazolam; 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit

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APA (6th Edition):

Stoffels, F. (2010). Polymorphisms in the promoter and enhancer region of CYP3A4. (Thesis). Freie Universität Berlin. Retrieved from http://dx.doi.org/10.17169/refubium-13048

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Stoffels, Felix. “Polymorphisms in the promoter and enhancer region of CYP3A4.” 2010. Thesis, Freie Universität Berlin. Accessed January 18, 2021. http://dx.doi.org/10.17169/refubium-13048.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Stoffels, Felix. “Polymorphisms in the promoter and enhancer region of CYP3A4.” 2010. Web. 18 Jan 2021.

Vancouver:

Stoffels F. Polymorphisms in the promoter and enhancer region of CYP3A4. [Internet] [Thesis]. Freie Universität Berlin; 2010. [cited 2021 Jan 18]. Available from: http://dx.doi.org/10.17169/refubium-13048.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stoffels F. Polymorphisms in the promoter and enhancer region of CYP3A4. [Thesis]. Freie Universität Berlin; 2010. Available from: http://dx.doi.org/10.17169/refubium-13048

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Manchester

22. Olivares Morales, Andres. Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.

Degree: PhD, 2016, University of Manchester

 The majority of drugs available on the market are intended to be administered through the oral route. To achieve the desired therapeutic effect, an orally… (more)

Subjects/Keywords: 615.7; Oral bioavailability; physiologically-based pharmacokinetics (PBPK); prediction; modelling and simulation; oxybutynin; CYP3A4; pre-clinical species; gastrointestinal; first pass metabolism; models

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APA (6th Edition):

Olivares Morales, A. (2016). Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/prediction-of-oral-drug-bioavailability-from-animalbased-extrapolation-towards-the-application-of-physiologicallybased-pharmacokinetic-modelling-and-simulation(9a6e9a95-1727-4f06-829d-a96f763fd8c9).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686770

Chicago Manual of Style (16th Edition):

Olivares Morales, Andres. “Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.” 2016. Doctoral Dissertation, University of Manchester. Accessed January 18, 2021. https://www.research.manchester.ac.uk/portal/en/theses/prediction-of-oral-drug-bioavailability-from-animalbased-extrapolation-towards-the-application-of-physiologicallybased-pharmacokinetic-modelling-and-simulation(9a6e9a95-1727-4f06-829d-a96f763fd8c9).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686770.

MLA Handbook (7th Edition):

Olivares Morales, Andres. “Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation.” 2016. Web. 18 Jan 2021.

Vancouver:

Olivares Morales A. Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. [Internet] [Doctoral dissertation]. University of Manchester; 2016. [cited 2021 Jan 18]. Available from: https://www.research.manchester.ac.uk/portal/en/theses/prediction-of-oral-drug-bioavailability-from-animalbased-extrapolation-towards-the-application-of-physiologicallybased-pharmacokinetic-modelling-and-simulation(9a6e9a95-1727-4f06-829d-a96f763fd8c9).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686770.

Council of Science Editors:

Olivares Morales A. Prediction of oral drug bioavailability : from animal-based extrapolation towards the application of physiologically-based pharmacokinetic modelling and simulation. [Doctoral Dissertation]. University of Manchester; 2016. Available from: https://www.research.manchester.ac.uk/portal/en/theses/prediction-of-oral-drug-bioavailability-from-animalbased-extrapolation-towards-the-application-of-physiologicallybased-pharmacokinetic-modelling-and-simulation(9a6e9a95-1727-4f06-829d-a96f763fd8c9).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686770


Linköping University

23. Nylén, Frank. Development of a reporter gene assay for PXR mediated CYP3A4 induction.

Degree: Chemistry and Biology, 2008, Linköping University

  PXR mediated elevation of CYP3A4 expression is a costly problem in drug development as well as a clinical problem due to clinically important drug… (more)

Subjects/Keywords: CYP3A4; induction; reporter gene assay; Chemistry; Kemi

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Nylén, F. (2008). Development of a reporter gene assay for PXR mediated CYP3A4 induction. (Thesis). Linköping University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14804

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Nylén, Frank. “Development of a reporter gene assay for PXR mediated CYP3A4 induction.” 2008. Thesis, Linköping University. Accessed January 18, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14804.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Nylén, Frank. “Development of a reporter gene assay for PXR mediated CYP3A4 induction.” 2008. Web. 18 Jan 2021.

Vancouver:

Nylén F. Development of a reporter gene assay for PXR mediated CYP3A4 induction. [Internet] [Thesis]. Linköping University; 2008. [cited 2021 Jan 18]. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14804.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nylén F. Development of a reporter gene assay for PXR mediated CYP3A4 induction. [Thesis]. Linköping University; 2008. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14804

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. Farrington, Rachael. Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions.

Degree: 2019, University of Adelaide

 Complementary and alternative medicine (CAM) is a broad set of health care practices that are not part of a country's own medical traditions and are… (more)

Subjects/Keywords: Complementary and Alternative Medicine; heoatotoxicity; CYP3A4

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APA (6th Edition):

Farrington, R. (2019). Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/119875

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Farrington, Rachael. “Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions.” 2019. Thesis, University of Adelaide. Accessed January 18, 2021. http://hdl.handle.net/2440/119875.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Farrington, Rachael. “Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions.” 2019. Web. 18 Jan 2021.

Vancouver:

Farrington R. Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions. [Internet] [Thesis]. University of Adelaide; 2019. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2440/119875.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Farrington R. Herbal medicine toxicity: The role of adulterants, contaminants and pharmacokinetic interactions. [Thesis]. University of Adelaide; 2019. Available from: http://hdl.handle.net/2440/119875

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of the Western Cape

25. Rassie, Candice. Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs .

Degree: 2020, University of the Western Cape

 Tuberculosis (TB) remains a global epidemic despite the fact that treatment has been available since the 1950’s. This disease is highly contagious and spreads via… (more)

Subjects/Keywords: Biosensor; Cytochrome P450; CYP3A4; Drug Metabolism; Ethambutol; Isoniazid; Metallodendrimer; Phenotype; Polypropyleneimine; Pyrazinamide; Real Samples; Rifampicin; Tuberculosis

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APA (6th Edition):

Rassie, C. (2020). Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/7235

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Rassie, Candice. “Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs .” 2020. Thesis, University of the Western Cape. Accessed January 18, 2021. http://hdl.handle.net/11394/7235.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Rassie, Candice. “Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs .” 2020. Web. 18 Jan 2021.

Vancouver:

Rassie C. Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs . [Internet] [Thesis]. University of the Western Cape; 2020. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/11394/7235.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Rassie C. Electrochemical cytochrome P450 enzymatic biosensors for the determination of the reactivity of TB drugs . [Thesis]. University of the Western Cape; 2020. Available from: http://hdl.handle.net/11394/7235

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Oslo

26. Ohm, Ingrid Kristine. Cyclosporin A som hemmer av CYP3A4 og CYP3A5.

Degree: 2010, University of Oslo

 Problemstilling Cyclosporin A (CsA) er en kalsinevrinhemmer som i stor grad brukes av pasienter som har gjennomgått organtransplantasjon. Denne pasientgruppen bruker ofte også flere andre… (more)

Subjects/Keywords: cyclosporin-A CYP3A4 CYP3A5 mekanismebasert hemning; VDP::568

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APA (6th Edition):

Ohm, I. K. (2010). Cyclosporin A som hemmer av CYP3A4 og CYP3A5. (Thesis). University of Oslo. Retrieved from http://urn.nb.no/URN:NBN:no-25114 ; https://www.duo.uio.no/handle/10852/11908 ; Fulltext https://www.duo.uio.no/bitstream/handle/10852/11908/3/Ingrid_Kristine_Ohm.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Ohm, Ingrid Kristine. “Cyclosporin A som hemmer av CYP3A4 og CYP3A5.” 2010. Thesis, University of Oslo. Accessed January 18, 2021. http://urn.nb.no/URN:NBN:no-25114 ; https://www.duo.uio.no/handle/10852/11908 ; Fulltext https://www.duo.uio.no/bitstream/handle/10852/11908/3/Ingrid_Kristine_Ohm.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Ohm, Ingrid Kristine. “Cyclosporin A som hemmer av CYP3A4 og CYP3A5.” 2010. Web. 18 Jan 2021.

Vancouver:

Ohm IK. Cyclosporin A som hemmer av CYP3A4 og CYP3A5. [Internet] [Thesis]. University of Oslo; 2010. [cited 2021 Jan 18]. Available from: http://urn.nb.no/URN:NBN:no-25114 ; https://www.duo.uio.no/handle/10852/11908 ; Fulltext https://www.duo.uio.no/bitstream/handle/10852/11908/3/Ingrid_Kristine_Ohm.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ohm IK. Cyclosporin A som hemmer av CYP3A4 og CYP3A5. [Thesis]. University of Oslo; 2010. Available from: http://urn.nb.no/URN:NBN:no-25114 ; https://www.duo.uio.no/handle/10852/11908 ; Fulltext https://www.duo.uio.no/bitstream/handle/10852/11908/3/Ingrid_Kristine_Ohm.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Montana

27. Skagen, Kasse Jean. Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant.

Degree: MS, 2014, University of Montana

 Researchers and clinicians are interested in how a patient’s individual genetic makeup could predict the appropriate medication and dose for that patient. One way to… (more)

Subjects/Keywords: pharmacogenomics; pharmacogenetics; human liver microsomes; genotype-phenotype associations; genetic variability; CYP3A4 CYP3A5 linkage disequilibrium; Confederated Salish and Kootenai Tribes; lymphocytes

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Skagen, K. J. (2014). Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant. (Masters Thesis). University of Montana. Retrieved from https://scholarworks.umt.edu/etd/4351

Chicago Manual of Style (16th Edition):

Skagen, Kasse Jean. “Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant.” 2014. Masters Thesis, University of Montana. Accessed January 18, 2021. https://scholarworks.umt.edu/etd/4351.

MLA Handbook (7th Edition):

Skagen, Kasse Jean. “Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant.” 2014. Web. 18 Jan 2021.

Vancouver:

Skagen KJ. Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant. [Internet] [Masters thesis]. University of Montana; 2014. [cited 2021 Jan 18]. Available from: https://scholarworks.umt.edu/etd/4351.

Council of Science Editors:

Skagen KJ. Interindividual Variability in the Cytochrome P450 3A4 Drug Metabolizing Enzyme: Effect of the CYP3A4*1G Genetic Variant. [Masters Thesis]. University of Montana; 2014. Available from: https://scholarworks.umt.edu/etd/4351

28. 中村, 裕義. 新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period.

Degree: Chiba University / 千葉大学

研究科: 千葉大学大学院薬学研究院

学位:千大院薬博乙第253号

Advisors/Committee Members: 千葉大学大学院薬学研究院.

Subjects/Keywords: CYP3A7; CYP3A4; neonate; drug metabolism; CYP3A7; CYP3A4; 新生児; 薬物代謝

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

中村, . (n.d.). 新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period. (Thesis). Chiba University / 千葉大学. Retrieved from http://opac.ll.chiba-u.jp/da/curator/900022711/

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

中村, 裕義. “新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period.” Thesis, Chiba University / 千葉大学. Accessed January 18, 2021. http://opac.ll.chiba-u.jp/da/curator/900022711/.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

中村, 裕義. “新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period.” Web. 18 Jan 2021.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

中村 . 新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period. [Internet] [Thesis]. Chiba University / 千葉大学; [cited 2021 Jan 18]. Available from: http://opac.ll.chiba-u.jp/da/curator/900022711/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

中村 . 新生児期の薬物代謝能に関する研究 : CYP3A活性を中心に : Study of the drug metabolic activities in neonatal period. [Thesis]. Chiba University / 千葉大学; Available from: http://opac.ll.chiba-u.jp/da/curator/900022711/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.


University of Helsinki

29. Kaartinen, Taavi. CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe.

Degree: Medicinska fakulteten, 2018, University of Helsinki

Protonipumpun estäjä omepratsolin S-isomeerin, esomepratsolin, on in vitro-tutkimuksissa osoitettu olevan lääkeaineiden metaboliaan osallistuvan sytokromi P450 CYP2C19-entsyymin mekanismiperustainen inhibiittori. CYP2C19 osallistuu maksassa lukuisten kliinisesti laajassa käytössä… (more)

Subjects/Keywords: sytokromi P450; CYP2C19; CYP3A4; CYP1A2; protonipumpun estäjä; esomepratsoli; pantopratsoli; midatsolaami; kofeiini; farmakokinetiikka; lääkeaineinteraktio; puoliintumisaika; metabolia; altistus; Cytochrome P-450 CYP2C19, Proton Pump Inhibitors, Pharmacokinetics, Drug Interactions; sytokromi P450; CYP2C19; CYP3A4; CYP1A2; protonipumpun estäjä; esomepratsoli; pantopratsoli; midatsolaami; kofeiini; farmakokinetiikka; lääkeaineinteraktio; puoliintumisaika; metabolia; altistus

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Kaartinen, T. (2018). CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe. (Masters Thesis). University of Helsinki. Retrieved from http://hdl.handle.net/10138/235814

Chicago Manual of Style (16th Edition):

Kaartinen, Taavi. “CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe.” 2018. Masters Thesis, University of Helsinki. Accessed January 18, 2021. http://hdl.handle.net/10138/235814.

MLA Handbook (7th Edition):

Kaartinen, Taavi. “CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe.” 2018. Web. 18 Jan 2021.

Vancouver:

Kaartinen T. CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe. [Internet] [Masters thesis]. University of Helsinki; 2018. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10138/235814.

Council of Science Editors:

Kaartinen T. CYP2C19 Inhibition Lasts for more than 72 Hours after High-Dose Esomeprazole: Estimation of CYP2C19 Half-Life Using Pantoprazole as an in Vivo Probe. [Masters Thesis]. University of Helsinki; 2018. Available from: http://hdl.handle.net/10138/235814


Universiteit Utrecht

30. Peters, Annelieke Katrien. Polybrominated Diphenyl Ethers, Aspects of the mechanism of action.

Degree: 2006, Universiteit Utrecht

 Polybrominated diphenylethers (PBDEs) are used as flame-retardant additives in a wide range of commercial products. Some PBDEs congeners are persistent in the environment, have lipophilic… (more)

Subjects/Keywords: Diergeneeskunde; polybrominated diphenyl ether; PBDE; brominated flame retardant; AhR; CYP1A1; CYP3A4

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Peters, A. K. (2006). Polybrominated Diphenyl Ethers, Aspects of the mechanism of action. (Doctoral Dissertation). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/8131

Chicago Manual of Style (16th Edition):

Peters, Annelieke Katrien. “Polybrominated Diphenyl Ethers, Aspects of the mechanism of action.” 2006. Doctoral Dissertation, Universiteit Utrecht. Accessed January 18, 2021. http://dspace.library.uu.nl:8080/handle/1874/8131.

MLA Handbook (7th Edition):

Peters, Annelieke Katrien. “Polybrominated Diphenyl Ethers, Aspects of the mechanism of action.” 2006. Web. 18 Jan 2021.

Vancouver:

Peters AK. Polybrominated Diphenyl Ethers, Aspects of the mechanism of action. [Internet] [Doctoral dissertation]. Universiteit Utrecht; 2006. [cited 2021 Jan 18]. Available from: http://dspace.library.uu.nl:8080/handle/1874/8131.

Council of Science Editors:

Peters AK. Polybrominated Diphenyl Ethers, Aspects of the mechanism of action. [Doctoral Dissertation]. Universiteit Utrecht; 2006. Available from: http://dspace.library.uu.nl:8080/handle/1874/8131

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