subject:(Breast Cancer)

Addis Ababa University

1. FETENE, KASAHUN AMOGNE. ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA .

Degree: 2014, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/5662

► Background: Breast cancer is a disease of public health importance. It results in high morbidity and mortality in women worldwide. Breast examination as a screening… (more)

▼ Background: Breast cancer is a disease of public health importance. It results in high morbidity and mortality in women worldwide. Breast examination as a screening tool for breast cancer in developing countries is advocated in view of its cost-effectiveness. Early detection of breast cancer using breast self-examination (BSE) plays an important role in decreasing its morbidity and mortality. Objective: To assess breast cancer awareness and practice of breast self-examination among female students in Madawalabu University Bale, Ethiopia, 2014 Methods: Cross-sectional study design was employed from December –June, 2014 in Madawalabu University. First the students were divided in to two practical strata, which are health science students and non-health science students. From each stratum, participants were selected by simple random sampling based on the proportion of the number of female students in each stratum that was 39 health science students and 383 non- health science students. Self administered questionnaire was used to collect the data. Data were entered with Epi Info version 3.5.1 and analyzed using SPSS statistical package version 16.0. Bivariate and multivariate logistic regression analysis was performed. Result: This study found that only [31.0%] of students had awareness about breast cancer and [15.5%] practiced BSE. The three main reasons for not doing BSE were belief that there is no problem with their breast [50.8%], not knowing the technique of BSE [40.0%], and Lack of privacy [15%]. Awareness about breast cancer and got information about BSE by health professionals were found significantly associated with practice of BSE. Respondents in the health related disciplines were six times more likely to practice BSE than other respondents. Conclusion: Awareness of breast cancer and BSE practice was found low in this study. Having information on the importance of BSE was predictor of BSE practice. Advisors/Committee Members: SR WORKINESH SINSHAW (BSc, RN, MSc) (advisor).

Subjects/Keywords: BREAST CANCER; BREAST

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APA (6^th Edition):

FETENE, K. A. (2014). ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/5662

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

FETENE, KASAHUN AMOGNE. “ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA .” 2014. Thesis, Addis Ababa University. Accessed October 17, 2019. http://etd.aau.edu.et/dspace/handle/123456789/5662.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

FETENE, KASAHUN AMOGNE. “ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA .” 2014. Web. 17 Oct 2019.

Vancouver:

FETENE KA. ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA . [Internet] [Thesis]. Addis Ababa University; 2014. [cited 2019 Oct 17]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5662.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

FETENE KA. ASSESSMENT OF BREAST CANCER KNOWLEDGE AND PRACTICE OF BREAST SELF - EXAMINATION AMONG FEMALE STUDENTS IN MADAWALABU UNIVERSITY, BALE, ETHIOPIA . [Thesis]. Addis Ababa University; 2014. Available from: http://etd.aau.edu.et/dspace/handle/123456789/5662

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New Mexico

2. Smith, Randi L. Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture.

Degree: Biomedical Sciences Graduate Program, 2015, University of New Mexico

URL: https://digitalrepository.unm.edu/biom_etds/93

► Our recent studies have shown that Tumor Adjacent Histologically Normal (TAHN) breast tissue demonstrates many of the characteristics of breast tumors. For example, through immunohistochemical… (more)

Subjects/Keywords: Cancer; Breast Cancer

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APA (6^th Edition):

Smith, R. L. (2015). Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture. (Masters Thesis). University of New Mexico. Retrieved from https://digitalrepository.unm.edu/biom_etds/93

Chicago Manual of Style (16^th Edition):

Smith, Randi L. “Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture.” 2015. Masters Thesis, University of New Mexico. Accessed October 17, 2019. https://digitalrepository.unm.edu/biom_etds/93.

MLA Handbook (7^th Edition):

Smith, Randi L. “Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture.” 2015. Web. 17 Oct 2019.

Vancouver:

Smith RL. Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture. [Internet] [Masters thesis]. University of New Mexico; 2015. [cited 2019 Oct 17]. Available from: https://digitalrepository.unm.edu/biom_etds/93.

Council of Science Editors:

Smith RL. Tumor Promoting Properties of Field Cancerized Fibroblasts in Cell Culture. [Masters Thesis]. University of New Mexico; 2015. Available from: https://digitalrepository.unm.edu/biom_etds/93

University of Georgia

3. Templeton, George Bowden. Partner adjustment and response to young women with breast cancer.

Degree: PhD, Child and Family Development, 2008, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/templeton_george_b_200808_phd

► Illness is a universal experience for families. In recent decades, increased attention has been paid to the role of the family in chronic illness and… (more)

▼ Illness is a universal experience for families. In recent decades, increased attention has been paid to the role of the family in chronic illness and disability, as well as the impact of illness throughout the entire family system. The quality of relationships is being increasingly identified as a source of considerable influence in health and related adjustment. Drawing on a biopsychosocial framework (Rolland, 1994a, 1994b; Engel, 1977, 1978, 1979, 1980), the purpose of this research was to examine the impact of breast cancer on partners, identify factors associated with partner adjustment, and describe profiles of supportive partners. To address these aims, two related studies were conducted. Study one reviewed literature examining the adjustment of partners to the diagnosis and treatment of breast cancer and answered two questions: (a) Do partners of women with BCA experience adjustment difficulties? and (b)What factors are associated with partner adjustment? This review determined that (a) partners experience physical health declines and are at risk for compromised immune functioning, (b) partners experience psychological distress that equal or exceeds that of patients, (c) partner experience disruptions at home, work, and in social activities, and (d) partners experience problems in their sexual relationship. Correlates of partner adjustment included medical characteristics, coping strategies, thought content, communication patterns, and social support. Study two investigated behaviors that young women perceive as supportive from their partners and factors that predicted partner support. Two questions were answered: (a) What partner behaviors do young women with BCA perceive as supportive? and (b) What factors predict the likelihood of partners being perceived as supportive? To address these questions, a series of two-step cluster analyses developed profiles of perceived partner behaviors in response to breast cancer, revealing two distinct groups: supportive and non-supportive. Binomial logistic regression determined that increases in patient symptom severity and psychological distress were associated with increased likelihood of patients perceiving partners as supportive, by factors of 1.83 and 1.97, respectively. In addition, patients reporting increased disruption of family life and their sexual relationship were less likely to perceive their partners as supportive, by factors of .28 and .35, respectively. Advisors/Committee Members: Stephanie Burwell.

Subjects/Keywords: breast cancer

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APA (6^th Edition):

Templeton, G. B. (2008). Partner adjustment and response to young women with breast cancer. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/templeton_george_b_200808_phd

Chicago Manual of Style (16^th Edition):

Templeton, George Bowden. “Partner adjustment and response to young women with breast cancer.” 2008. Doctoral Dissertation, University of Georgia. Accessed October 17, 2019. http://purl.galileo.usg.edu/uga_etd/templeton_george_b_200808_phd.

MLA Handbook (7^th Edition):

Templeton, George Bowden. “Partner adjustment and response to young women with breast cancer.” 2008. Web. 17 Oct 2019.

Vancouver:

Templeton GB. Partner adjustment and response to young women with breast cancer. [Internet] [Doctoral dissertation]. University of Georgia; 2008. [cited 2019 Oct 17]. Available from: http://purl.galileo.usg.edu/uga_etd/templeton_george_b_200808_phd.

Council of Science Editors:

Templeton GB. Partner adjustment and response to young women with breast cancer. [Doctoral Dissertation]. University of Georgia; 2008. Available from: http://purl.galileo.usg.edu/uga_etd/templeton_george_b_200808_phd

University of Georgia

4. Zak-Hunter, Lisa Marie. The initiation of couple relationship discussions among young women with breast cancer.

Degree: MS, Child and Family Development, 2008, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/zak-hunter_lisa_m_200812_ms

► Literature has shown that the quality of the couple relationship plays an integral role in a woman’s adjustment to diagnosis and treatment of breast cancer.… (more)

Subjects/Keywords: Breast cancer

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APA (6^th Edition):

Zak-Hunter, L. M. (2008). The initiation of couple relationship discussions among young women with breast cancer. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/zak-hunter_lisa_m_200812_ms

Chicago Manual of Style (16^th Edition):

Zak-Hunter, Lisa Marie. “The initiation of couple relationship discussions among young women with breast cancer.” 2008. Masters Thesis, University of Georgia. Accessed October 17, 2019. http://purl.galileo.usg.edu/uga_etd/zak-hunter_lisa_m_200812_ms.

MLA Handbook (7^th Edition):

Zak-Hunter, Lisa Marie. “The initiation of couple relationship discussions among young women with breast cancer.” 2008. Web. 17 Oct 2019.

Vancouver:

Zak-Hunter LM. The initiation of couple relationship discussions among young women with breast cancer. [Internet] [Masters thesis]. University of Georgia; 2008. [cited 2019 Oct 17]. Available from: http://purl.galileo.usg.edu/uga_etd/zak-hunter_lisa_m_200812_ms.

Council of Science Editors:

Zak-Hunter LM. The initiation of couple relationship discussions among young women with breast cancer. [Masters Thesis]. University of Georgia; 2008. Available from: http://purl.galileo.usg.edu/uga_etd/zak-hunter_lisa_m_200812_ms

University of Georgia

5. Dunlop, Colin Derek. What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease.

Degree: MA, Journalism and Mass Communication, 2009, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/dunlop_colin_d_200912_ma

► Breast cancer and heart disease are two topics at the forefront of women’s health. Competing interests have helped to skew perceptions that breast cancer is… (more)

Subjects/Keywords: Breast cancer

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APA (6^th Edition):

Dunlop, C. D. (2009). What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease. (Masters Thesis). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/dunlop_colin_d_200912_ma

Chicago Manual of Style (16^th Edition):

Dunlop, Colin Derek. “What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease.” 2009. Masters Thesis, University of Georgia. Accessed October 17, 2019. http://purl.galileo.usg.edu/uga_etd/dunlop_colin_d_200912_ma.

MLA Handbook (7^th Edition):

Dunlop, Colin Derek. “What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease.” 2009. Web. 17 Oct 2019.

Vancouver:

Dunlop CD. What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease. [Internet] [Masters thesis]. University of Georgia; 2009. [cited 2019 Oct 17]. Available from: http://purl.galileo.usg.edu/uga_etd/dunlop_colin_d_200912_ma.

Council of Science Editors:

Dunlop CD. What color is today’s newspaper journalism: red or pink?: a content analysis of national newspaper coverage on women’s breast cancer and heart disease. [Masters Thesis]. University of Georgia; 2009. Available from: http://purl.galileo.usg.edu/uga_etd/dunlop_colin_d_200912_ma

University of Alberta

6. Bernier, Ashlyn. Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis.

Degree: PhD, Medical Sciences - Laboratory Medicine and Pathology, 2011, University of Alberta

URL: https://era.library.ualberta.ca/files/db78td08r

► Breast cancer is the second leading cause of cancer death in Canadian women. In these patients, mortality is due to metastasis of cancer cells from… (more)

▼ Breast cancer is the second leading cause of cancer death in Canadian women. In these patients, mortality is due to metastasis of cancer cells from the breast to distant organs, resulting in impairment of function. To metastasize, cells must move through the stroma of the breast, enter the circulation, survive transit, exit the circulation, and form a secondary tumor. A critical component of this metastatic cascade is cancer cell motility. It is not fully understood how breast cancer cells gain the ability to move or what signaling pathways mediate these events, and identification of critical components of these pathways would represent potential targets for anti-metastatic therapies. The MUC1 glycoprotein is expressed on the apical membrane of normal breast epithelia. In many human breast carcinomas, MUC1 is overexpressed and loses apical polarization, events that correlate with increased metastasis. The contribution of MUC1 overexpression to increased metastasis is not completely understood, with the majority of studies attributing an anti-adhesive role to MUC1. Several critical steps of the metastatic cascade require cell adhesion, and it has been reported that MUC1 is a ligand for ICAM-1, which is expressed throughout the migratory tract of a metastasizing breast cancer cell. It was subsequently reported that MUC1/ICAM-1 binding initiates calcium oscillations, cytoskeletal reorganization, and cell migration, suggesting that binding could be important in metastasis. Here, we investigate the mechanism of MUC1/ICAM-1 binding induced signaling. We show that Src kinase is a critical component of the MUC1/ICAM-1 signalling axis, and that MUC1 forms constitutive dimers which are required for Src recruitment and ICAM-1 binding induced signaling. We show that MUC1 dimers are not covalently linked and do not require cytoplasmic domain cysteine residues, contrary to other reports. We show that MUC1 extracellular domain shedding is not required for dimerization, Src recruitment, or ICAM-1 binding induced calcium oscillations, although it is required for migration. Lastly, we show that autoproteolytic cleavage of MUC1 is not required for normal function. These results reveal information on the mechanism of MUC1/ICAM-1 signalling, which can be used to identify novel targets and combinational strategies for anti-metastatic therapy in breast cancer.

Subjects/Keywords: Breast Cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bernier, A. (2011). Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/db78td08r

Chicago Manual of Style (16^th Edition):

Bernier, Ashlyn. “Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis.” 2011. Doctoral Dissertation, University of Alberta. Accessed October 17, 2019. https://era.library.ualberta.ca/files/db78td08r.

MLA Handbook (7^th Edition):

Bernier, Ashlyn. “Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis.” 2011. Web. 17 Oct 2019.

Vancouver:

Bernier A. Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis. [Internet] [Doctoral dissertation]. University of Alberta; 2011. [cited 2019 Oct 17]. Available from: https://era.library.ualberta.ca/files/db78td08r.

Council of Science Editors:

Bernier A. Mechanisms of MUC1/ICAM-1 signalling in breast cancer metastasis. [Doctoral Dissertation]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/db78td08r

Texas A&M University

7. Vanderlaag, Kathryn Elisabeth. Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells.

Degree: 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-1381

► One in 8 women will be diagnosed with breast cancer in the United States and estrogen receptor (ER) status largely influences the type and subsequent… (more)

▼ One in 8 women will be diagnosed with breast cancer in the United States and estrogen receptor (ER) status largely influences the type and subsequent success of treatment employed. Although ER-positive breast cancer can be treated with endocrine therapy, the more invasive ER-negative breast cancer is non-responsive to this therapy and cytotoxic agents are often utilized which are associated with many adverse side effects. Consequently, there is a genuine need to develop more effective, less toxic treatments for invasive breast cancer. Indole-3-carbinol is a phytochemical found in cruciferous vegetables and one of its major metabolites, 3,3?-diindolylmethane (DIM), exhibits a broad range of anticancer and antitumorigenic activities. ER-negative MDA-MB-231 and MDA-MB-453 breast cancer cell growth was inhibited after treatment with a novel series of methylenesubstituted DIMs (C-DIMs), namely 1,1-bis(3?-indolyl)-1-(p-substitutedphenyl) methanes containing trifluoromethyl (DIM-C-pPhCF3), t-butyl (DIM-C-pPhtBu) and phenyl (DIM-C-pPhC6H5) groups. In addition, DIM-C-pPhC6H5 (40 mg/kg/d) inhibited tumor growth in nude mice bearing MDA-MB-231 cells as xenografts. Treatment of breast cancer cells with C-DIMs lead to downregulation of cyclin D1 and induction of non-steroidal anti-inflammatory drug-activated gene 1. Detection of necrosis, caspasedependent or caspase-independent apoptosis were not observed in breast cancer cells treated with C-DIMs, however autophagic cell death was induced by C-DIMs. DIM and ring-substituted DIMs have exhibited antitumorigenic activity in tumor murine mammary models. An investigation into the mechanism of cell death induced by DIM and 5,5?-dibromoDIM (5,5?-diBrDIM) in both ER-positive (MCF-7) and ERnegative (MDA-MB-231) breast cancer cells revealed modulation of several key signaling pathways involved in growth control. Both DIM and 5,5?-diBrDIM downregulated cyclin D1, although only 5,5?-diBrDIM induced a depolarization of the mitochondrial membrane. In addition, apoptosis was observed in MCF-7 cells treated with 5,5?-diBrDIM but not MDA-MB-231 cells. In summary, C-DIMs may represent new mechanism-based agents for treatment of breast cancer through induction of autophagic cell death. The ring-substituted DIMs correspond to a novel class of uncharged mitochondrial poisons that are also highly effective in inhibiting breast cancer cell growth. Results of this research provide evidence for the potential role of two new series of DIM analogs for the treatment of highly aggressive breast cancer. Advisors/Committee Members: Safe, Stephen H. (advisor), Burghardt, Robert C. (committee member), Phillips, Timothy D. (committee member), Porter, Weston W. (committee member).

Subjects/Keywords: breast cancer

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APA (6^th Edition):

Vanderlaag, K. E. (2009). Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells. (Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-1381

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vanderlaag, Kathryn Elisabeth. “Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells.” 2009. Thesis, Texas A&M University. Accessed October 17, 2019. http://hdl.handle.net/1969.1/ETD-TAMU-1381.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vanderlaag, Kathryn Elisabeth. “Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells.” 2009. Web. 17 Oct 2019.

Vancouver:

Vanderlaag KE. Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells. [Internet] [Thesis]. Texas A&M University; 2009. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1381.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vanderlaag KE. Mechanisms of growth inhibition induced by methylene-substituted and ring-substituted dims in breast cancer cells. [Thesis]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-1381

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Addis Ababa University

8. DURETI, GENA. KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS .

Degree: 2013, Addis Ababa University

URL: http://etd.aau.edu.et/dspace/handle/123456789/7004

► Breast cancer is one of the most common cancers and a major cause of death among women worldwide. Each year, breast cancer is newly diagnosed… (more)

Subjects/Keywords: Breast cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

DURETI, G. (2013). KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS . (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/7004

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

DURETI, GENA. “KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS .” 2013. Thesis, Addis Ababa University. Accessed October 17, 2019. http://etd.aau.edu.et/dspace/handle/123456789/7004.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

DURETI, GENA. “KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS .” 2013. Web. 17 Oct 2019.

Vancouver:

DURETI G. KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS . [Internet] [Thesis]. Addis Ababa University; 2013. [cited 2019 Oct 17]. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7004.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

DURETI G. KNOWLEDGE AND PERCEPTION REGARDING BREAST CANCER PREVENTION AMONG UNIVERSITY STUDENTS . [Thesis]. Addis Ababa University; 2013. Available from: http://etd.aau.edu.et/dspace/handle/123456789/7004

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hawaii – Manoa

9. Higa, Jason Kenji. Inflammation and breast cancer prevention by phyllostachys edulis extract.

Degree: 2016, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/102030

►

Ph.D. University of Hawaii at Manoa 2013.

Obesity affects roughly one-third of American adults, in which chronic inflammation and lipotoxicity are disorders that are frequently… (more)

▼

Ph.D. University of Hawaii at Manoa 2013.

Obesity affects roughly one-third of American adults, in which chronic inflammation and lipotoxicity are disorders that are frequently found in conjunction. An estimated 232,340 American women are predicted to be diagnosed with breast cancer (BrCa) in 2013, and 39,620 are expected to die from it. Obesity does not guarantee that a woman will develop BrCa, but it increases her risk of developing it. This dissertation focuses on the potential therapeutic effects of an extract from the bamboo Phyllostachys edulis as related to lipotoxicity-induced inflammation and breast cancer. Bamboo extract (BEX) has previously demonstrated anti-lipotoxic effects. In the present study, which used in vitro cell culture models mimicking lipotoxic conditions, BEX was found to decrease production of the inflammatory cytokines IL-6 and MCP-1, inhibit nuclear translocation of the proinflammatory transcription factors NF-κB and AP-1, and increase activity of the antiinflammatory transcription factors Nrf2 and PPARγ. An in vivo study showed that BEX could also inhibit MCP-1 production in mice when supplemented into a high fat diet. Tricin and 7-O-methyl tricin (7MT) were isolated from BEX, and both compounds had inhibitory effects on lipotoxicity-induced MCP-1 production. On the topic of breast cancer, BEX showed inhibitory effects on multiple BrCa cell lines while showing minimal toxicity to MCF-10A, a non-carcinoma mammary cell line. BEX appeared to induce protective effects in MCF-10A cells by increasing expression of genes involved with DNA damage and repair and inducing antioxidant signaling and activity. BrCa cell lines showed varied responses to inhibition by tricin, 7MT, and other compounds reportedly isolated from P. edulis. BEX did not bind to or activate estrogen receptor alpha at physiological levels. A proteomics study carried out on MCF7 cells treated with BEX, tricin, and 7MT suggested that BEX and its compounds may alter cytoskeletal structures, and inhibit mTOR and IGF-1R signaling.

Subjects/Keywords: breast cancer

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APA (6^th Edition):

Higa, J. K. (2016). Inflammation and breast cancer prevention by phyllostachys edulis extract. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/102030

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Higa, Jason Kenji. “Inflammation and breast cancer prevention by phyllostachys edulis extract.” 2016. Thesis, University of Hawaii – Manoa. Accessed October 17, 2019. http://hdl.handle.net/10125/102030.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Higa, Jason Kenji. “Inflammation and breast cancer prevention by phyllostachys edulis extract.” 2016. Web. 17 Oct 2019.

Vancouver:

Higa JK. Inflammation and breast cancer prevention by phyllostachys edulis extract. [Internet] [Thesis]. University of Hawaii – Manoa; 2016. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10125/102030.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Higa JK. Inflammation and breast cancer prevention by phyllostachys edulis extract. [Thesis]. University of Hawaii – Manoa; 2016. Available from: http://hdl.handle.net/10125/102030

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

10. Chau, Hau-yan. Symptom clusters among Chinese women with breast cancer.

Degree: MPH, 2012, University of Hong Kong

URL: Chau, H. [周厚仁]. (2012). Symptom clusters among Chinese women with breast cancer. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4842256 ; http://dx.doi.org/10.5353/th_b4842256 ; http://hdl.handle.net/10722/179891

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Background: breast cancer patients were found to experience multiple concurrent symptoms. These concurrent symptoms (termed symptom cluster) could have synergistic effects on patient functional status… (more)

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Background: breast cancer patients were found to experience multiple concurrent symptoms. These concurrent symptoms (termed symptom cluster) could have synergistic effects on patient functional status and quality of life. Understanding symptom cluster provided us new insight in symptom assessment and symptom management. Previous studies on symptom cluster among breast cancer patients focused on Caucasian. The current study attempt to identify symptom cluster and the factors associated with it among Chinese breast cancer patients. Methods: this study was a secondary analysis on a sample of 348 breast cancer patients. Data on symptom distress (assessed by Memorial symptom Assessment scale Short Form) was retrieved. Symptom clusters were identified through factor analysis using principal components method and Varimax rotation. Demographics and medical characteristics were proposed to be associated with symptom cluster. Uni-variate analysis and linear regression performed on these variables. Results: four symptom clusters (namely gastrointestinal cluster, general malaise cluster, self image cluster, and cutaneous cluster) were identified. Recurrence of breast cancer and chemotherapy were associated with either gastrointestinal cluster or general malaise cluster. Age, cancer status and occupation were associated with self image cluster while no variable was associated with cutaneous cluster. Conclusion: The current study provided empirical evidence that Chinese breast cancer patients experienced similar symptom clusters as Caucasian. Future study could be done to verify these four symptom clusters and identify underlying mechanism. Recommendations: health care providers could pay more attention to those suffer from breast cancer recurrence or currently receiving chemotherapy. These patients tend to experience gastrointestinal cluster and general malaise cluster. Clinical setting and evaluation tools could be adjusted to fit these high risk groups.

published_or_final_version

Public Health

Master

Master of Public Health

Subjects/Keywords: Breast - Cancer.

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APA (6^th Edition):

Chau, H. (2012). Symptom clusters among Chinese women with breast cancer. (Masters Thesis). University of Hong Kong. Retrieved from Chau, H. [周厚仁]. (2012). Symptom clusters among Chinese women with breast cancer. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4842256 ; http://dx.doi.org/10.5353/th_b4842256 ; http://hdl.handle.net/10722/179891

Chicago Manual of Style (16^th Edition):

Chau, Hau-yan. “Symptom clusters among Chinese women with breast cancer.” 2012. Masters Thesis, University of Hong Kong. Accessed October 17, 2019. Chau, H. [周厚仁]. (2012). Symptom clusters among Chinese women with breast cancer. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4842256 ; http://dx.doi.org/10.5353/th_b4842256 ; http://hdl.handle.net/10722/179891.

MLA Handbook (7^th Edition):

Chau, Hau-yan. “Symptom clusters among Chinese women with breast cancer.” 2012. Web. 17 Oct 2019.

Vancouver:

Chau H. Symptom clusters among Chinese women with breast cancer. [Internet] [Masters thesis]. University of Hong Kong; 2012. [cited 2019 Oct 17]. Available from: Chau, H. [周厚仁]. (2012). Symptom clusters among Chinese women with breast cancer. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4842256 ; http://dx.doi.org/10.5353/th_b4842256 ; http://hdl.handle.net/10722/179891.

Council of Science Editors:

Chau H. Symptom clusters among Chinese women with breast cancer. [Masters Thesis]. University of Hong Kong; 2012. Available from: Chau, H. [周厚仁]. (2012). Symptom clusters among Chinese women with breast cancer. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_b4842256 ; http://dx.doi.org/10.5353/th_b4842256 ; http://hdl.handle.net/10722/179891

Cornell University

11. Felice, Dana. Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis .

Degree: 2009, Cornell University

URL: http://hdl.handle.net/1813/13483

► Among women in the United States, breast cancer is the most frequently occurring cancer and is the second-leading cause of cancer deaths. Approximately 30% of… (more)

▼ Among women in the United States, breast cancer is the most frequently occurring cancer and is the second-leading cause of cancer deaths. Approximately 30% of cancer risk is estimated to be attributed to diet. Apple consumption has been correlated with reduced breast cancer risk as well as more favorable prognostic factors. The first objective was to develop a more efficient methylene blue assay for cell counting which could be applied to a broader range of cell densities and various cell culture plates. A linear relationship (r2>0.99) was established between cell number and absorbance at 570 nm wavelength when the modified methylene blue assay was applied to three cell lines plated in a broad range of cell densities in 4 different types of culture plates. This modified methylene blue assay is a powerful tool for any application requiring a versatile, efficient, and accurate method of cell counting, especially in the research of natural products, bioactive compounds, phytochemicals, functional foods and nutraceuticals. The second objective was to determine whether whole apple extracts and purified compounds from apples interfered with IGF-Imediated signal transduction pathways in MCF-7 human breast cancer cells. Quercetin-3-Glucoside (Q-3-G) proved to be surprisingly effective, inhibiting IGF-Iinduced MCF-7 cell proliferation more potently than FBS-stimulated proliferation, as well as more potently than quercetin inhibited cell growth. Q-3-G blocked cell cycle progression and induced apoptosis via down-regulated Akt phosphorylation, Cyclin D1 and CDK-4 expression, and increased Caspase-9 and PARP cleavage. The results help to explain the mechanisms by which apple consumption may reduce breast cancer risk. Additionally, such studies of purified compounds contribute to the understanding of cancer cell behavior and may inform future endeavors in chemotherapeutic drug design. The third objective was to determine the effects of apple phytochemical extracts on cell proliferation and apoptosis in mammary tissues in DMBA-treated Sprague-Dawley rats in vivo. The expression of PCNA, BrdU-labeled cells, Cyclin D1 and Bcl-2 decreased, and Bax expression and apoptosis increased in the apple treated groups. These results demonstrate the potent capacity of fresh apples to suppress promotion and progression of DMBA-initiated mammary carcinogenesis in rats.

Subjects/Keywords: Breast Cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Felice, D. (2009). Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis . (Thesis). Cornell University. Retrieved from http://hdl.handle.net/1813/13483

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Felice, Dana. “Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis .” 2009. Thesis, Cornell University. Accessed October 17, 2019. http://hdl.handle.net/1813/13483.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Felice, Dana. “Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis .” 2009. Web. 17 Oct 2019.

Vancouver:

Felice D. Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis . [Internet] [Thesis]. Cornell University; 2009. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/1813/13483.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Felice D. Apple Phytochemicals In The Prevention Of Breast Cancer: Effects On Cell Proliferation And Apoptosis . [Thesis]. Cornell University; 2009. Available from: http://hdl.handle.net/1813/13483

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wake Forest University

12. Dewi, Fitriya Nur Annisa. THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES.

Degree: 2013, Wake Forest University

URL: http://hdl.handle.net/10339/39018

► Diet has been thought to modify developmental regulation and subsequently influence later-life susceptibility to various diseases including cancer. Meta-analyses showed that the intake of soy,… (more)

▼ Diet has been thought to modify developmental regulation and subsequently influence later-life susceptibility to various diseases including cancer. Meta-analyses showed that the intake of soy, which contains the phytoestrogenic compounds isoflavones (IFs), is associated with reduced breast cancer risk. A similar relationship has been reported for soy and endometrial cancer, although the evidence is more limited. Interestingly, the inverse association between soy and breast cancer is more consistent when soy exposure occurs preceding puberty. Our primary aim was to investigate the effect of soy consumption beginning pre-adulthood on the breast and uterine tissues in relation to estrogen action. We utilized two animal models: cynomolgus macaques and apolipoprotein E-null mice. The macaque study longitudinally assessed tissue changes across pubertal development to model young girls consuming a North American diet with/without soy IF exposure. We found that soy intake did not alter pubertal growth, menarche, or uterine development. Soy exposure initiated at puberty promoted mammary gland differentiation which resulted in a breast composed of abundant mature lobular structures in adulthood, a phenotype consistent with low cancer risk. We observed a modestly lower expression of ERs and ER activity markers, suggesting that early soy exposure could potentially result in lower estrogen-responsiveness in the adult breast. These changes were not associated with differential circulating estradiol and progesterone, CpG methylation within the specific promoter regions examined, or expression of intramammary estrogen-metabolizing enzymes. To explain whether the soy effect is dependent on the primary IF metabolite equol, we conducted a study whereby mice were modified to have equol-producing vs. non-equol-producing capability to model the low frequency of equol production observed in human populations. Mice were fed dietary soy with/without exogenous equol starting at peripubertal age. Equol, but not a soy diet per se, modulated estrogen-dependent uterine responses; the effect was less clear in the breast. Female equol producers had lower estrogenic reproductive tissue phenotypes compared to nonproducers, regardless of IF dose. Collectively, our findings indicate that pubertal exposure to soy may have a subtle effect in promoting breast differentiation and downregulating estrogen-responsiveness. Equol and/or equol-producing microbiota may influence estrogen-associated tissue phenotype and response to soy diet.

Subjects/Keywords: Breast cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dewi, F. N. A. (2013). THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES. (Thesis). Wake Forest University. Retrieved from http://hdl.handle.net/10339/39018

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dewi, Fitriya Nur Annisa. “THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES.” 2013. Thesis, Wake Forest University. Accessed October 17, 2019. http://hdl.handle.net/10339/39018.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dewi, Fitriya Nur Annisa. “THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES.” 2013. Web. 17 Oct 2019.

Vancouver:

Dewi FNA. THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES. [Internet] [Thesis]. Wake Forest University; 2013. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10339/39018.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dewi FNA. THE EFFECTS OF PUBERTAL EXPOSURE TO DIETARY SOY ISOFLAVONES ON THE BREAST AND REPRODUCTIVE TISSUES. [Thesis]. Wake Forest University; 2013. Available from: http://hdl.handle.net/10339/39018

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Wake Forest University

13. Swanner, Jessica Lynn. SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION.

Degree: 2017, Wake Forest University

URL: http://hdl.handle.net/10339/82205

► A woman’s lifetime risk of being diagnosed with breast cancer is approximately 1 in 8, and it is estimated that over 40,000 women will die… (more)

Subjects/Keywords: breast cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Swanner, J. L. (2017). SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION. (Thesis). Wake Forest University. Retrieved from http://hdl.handle.net/10339/82205

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Swanner, Jessica Lynn. “SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION.” 2017. Thesis, Wake Forest University. Accessed October 17, 2019. http://hdl.handle.net/10339/82205.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Swanner, Jessica Lynn. “SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION.” 2017. Web. 17 Oct 2019.

Vancouver:

Swanner JL. SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION. [Internet] [Thesis]. Wake Forest University; 2017. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10339/82205.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Swanner JL. SILVER NANOPARTICLES ARE EFFECTIVE FOR THE TREATMENT OF CLAUDIN LOW BREAST CANCER AND OTHER MESENCHYMAL CANCERS WITH HIGH ZEB1 EXPRESSION. [Thesis]. Wake Forest University; 2017. Available from: http://hdl.handle.net/10339/82205

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Liu, Tianli. Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking.

Degree: PhD, Division of Biology and Medicine. Epidemiology, 2009, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:198/

► This dissertation focuses on the long term health outcomes of prenatal exposure to cigarette smoke. We hypothesize that exposure to toxins through maternal smoking could… (more)

▼ This dissertation focuses on the long term health outcomes of prenatal exposure to cigarette smoke. We hypothesize that exposure to toxins through maternal smoking could affect the hypothalamus of the fetal brain, subsequently leading to a long term impact on physical and mental health. Three epidemiologic studies were conducted to test this hypothesis. Study one is a prospective cohort study examining whether maternal smoking during pregnancy increased the risk of benign breast disease (BBD) among adult female offspring. The study results suggested that women whose mothers smoked during pregnancy were more than two times more likely to develop BBD in their adulthood than women whose mothers never smoked during pregnancy. We consider that the findings were consistent with our hypothesis. The hypothalamus is the control center of the brain for sex hormone release. A toxic influence on the hypothalamus might induce a sex hormone imbalance which subsequently leads to BBD. Study two further examined the relationship between postnatal smoking exposures and risk of BBD. None of these postnatal smoking exposures were found to be independently associated with the risk of BBD. These findings confirmed our hypothesis that exposure to cigarette smoking during the prenatal period, instead of the postnatal period, predicted an increased risk of BBD. The programming of the hypothalamus is taking place during the prenatal period, when the blood-brain barrier, which prevents the passage of many toxic agents into the brain, is not fully developed. We conclude that the prenatal period is a unique time during which toxic agents can impact the fetal brain. As the hypothalamus not only controls sex hormone balance, but also anger and rage, in study three, we examined the relationship between maternal smoking during pregnancy and anger temperament of the offspring using several sets of analyses. The results consistently showed that maternal smoking during pregnancy was associated with an increased level of anger temperament among adult offspring. We consider the results support our hypothesis. Prenatal exposure to cigarette smoking might have disturbed the normal development and organization of the hypothalamus, and in doing so, would have an impact on anger temperament. Advisors/Committee Members: Buka, Stephen (director), Gatsonis, Constantine (reader), Baylin, Ana (reader).

Subjects/Keywords: breast cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, T. (2009). Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:198/

Chicago Manual of Style (16^th Edition):

Liu, Tianli. “Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking.” 2009. Doctoral Dissertation, Brown University. Accessed October 17, 2019. https://repository.library.brown.edu/studio/item/bdr:198/.

MLA Handbook (7^th Edition):

Liu, Tianli. “Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking.” 2009. Web. 17 Oct 2019.

Vancouver:

Liu T. Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking. [Internet] [Doctoral dissertation]. Brown University; 2009. [cited 2019 Oct 17]. Available from: https://repository.library.brown.edu/studio/item/bdr:198/.

Council of Science Editors:

Liu T. Long Term Health Outcomes of Prenatal Exposure to Cigarette Smoking. [Doctoral Dissertation]. Brown University; 2009. Available from: https://repository.library.brown.edu/studio/item/bdr:198/

Wake Forest University

15. Liu, Yin. BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY.

Degree: 2018, Wake Forest University

URL: http://hdl.handle.net/10339/90710

► Breast cancer is one of major public health problem worldwide. However, the underlying molecular mechanism of breast cancer progression and metastasis is not well understood.… (more)

Subjects/Keywords: Breast cancer

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, Y. (2018). BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY. (Thesis). Wake Forest University. Retrieved from http://hdl.handle.net/10339/90710

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Liu, Yin. “BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY.” 2018. Thesis, Wake Forest University. Accessed October 17, 2019. http://hdl.handle.net/10339/90710.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Liu, Yin. “BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY.” 2018. Web. 17 Oct 2019.

Vancouver:

Liu Y. BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY. [Internet] [Thesis]. Wake Forest University; 2018. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10339/90710.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Liu Y. BREAST CANCER PROGRESSION AND METASTASIS: DISCOVERY OF NOVEL GENES AND THEIR FUNCTIONAL STUDY. [Thesis]. Wake Forest University; 2018. Available from: http://hdl.handle.net/10339/90710

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

16. Estrella, Brian, 1989-. Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene.

Degree: PhD, Toxicology, 2018, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/57543/

► Fry is an evolutionarily-conserved gene involved in cellular differentiation, division, morphology, polarity, and adhesion. Decreased expression of the FRY protein in breast cancer cell lines… (more)

▼ Fry is an evolutionarily-conserved gene involved in cellular differentiation, division, morphology, polarity, and adhesion. Decreased expression of the FRY protein in breast cancer cell lines reduced the expression of gene networks associated with epithelial differentiation, morphology, polarity and adhesion. Ectopic expression of the wild-type rat Fry gene in human breast cancer cells restored a gene expression profile associated with differentiation, suppression of epithelial-mesenchymal transition. Breast cancer cells expressing wild-type Fry at physiological levels reacquired a non-transformed morphology in vitro and a non-tumorigenic in vivo phenotype in the nude mouse xenograft model. We further determined that expression of FRY mRNA and protein correlated with breast cancer phenotypes such as Elston tumor grade, estrogen receptor, progesterone receptor, and Her2 receptor status. Despite these finding, significant gaps in knowledge remain in our understanding of how FRY expression is decreased during tumor progression. Based on preliminary data, we hypothesized modulation of FRY expression occurs through epigenetic mechanisms which include DNA methylation, histone modification and chromatin remodeling, and the activity/interaction of non-coding RNAs. To understand how DNA methylation regulates FRY transcription in breast tumors, we examined publicly available RNA-seq and DNA methylation data from The Cancer Genome Atlas (TCGA). Analysis of FRY promoter methylation revealed no significant changes in DNA methylation in normal vs. breast tumors. However, when we subdivided the tumors by hormone receptor status, we observed an increase in FRY promoter methylation in ER- and PR- breast tumors. Treatment of various breast cancer cell lines with the DNMT inhibitor, 5-Aza-2-deoxycytidine, resulted in upregulation of FRY mRNA and protein expression. These results indicate that loss of FRY expression may in part be due to increased methylation. To elucidate the role of chromatin in the role of FRY expression we searched publicly available chromatin immunoprecipitation sequencing data from the Encyclopedia of DNA elements (ENCODE) to identify key chromatin markers and transcription factors that bind to the FRY promoter. Using this data, we demonstrated that FRY has a canonical gene promoter characterized by low levels of H3K4me1 and high levels H3K4me2/me3. Furthermore, using data from the ENCODE, we identified 28 transcription factors predicted to binds to the FRY gene promoter, the most significant of which were estrogen receptor 1 (ESR1) and progesterone receptor (PR). To determine if histone deacteylases (HDACs) impacted FRY expression, we dosed various breast cancer cell lines with commonly used the HDAC inhibitors, Trichostatin-A and Panobinostat (LBH589). Through treatment of our cell lines with these HDAC inhibitors, we were able to modulate FRY expression, indicating that its expression is in part regulated by protein acetylation. Next, we explored whether transcriptional repressor, enhancer of Zeste Homolog 2… Advisors/Committee Members: Zarbl, Helmut (chair), School of Graduate Studies.

Subjects/Keywords: Breast – Cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Estrella, Brian, 1. (2018). Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/57543/

Chicago Manual of Style (16^th Edition):

Estrella, Brian, 1989-. “Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene.” 2018. Doctoral Dissertation, Rutgers University. Accessed October 17, 2019. https://rucore.libraries.rutgers.edu/rutgers-lib/57543/.

MLA Handbook (7^th Edition):

Estrella, Brian, 1989-. “Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene.” 2018. Web. 17 Oct 2019.

Vancouver:

Estrella, Brian 1. Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene. [Internet] [Doctoral dissertation]. Rutgers University; 2018. [cited 2019 Oct 17]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/57543/.

Council of Science Editors:

Estrella, Brian 1. Epigenetic regulation of Fry: a mammary carcinoma susceptibility gene. [Doctoral Dissertation]. Rutgers University; 2018. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/57543/

Rutgers University

17. Hemler, Jennifer R., 1972-. Life with, after, or beyond cancer: breast cancer survivorship and the new normal.

Degree: PhD, Sociology, 2015, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/48509/

►

I examine how women “move on,” or are unable to, after a diagnosis of breast cancer. I interviewed 80 survivors of various types and stages… (more)

▼

I examine how women “move on,” or are unable to, after a diagnosis of breast cancer. I interviewed 80 survivors of various types and stages of breast cancer to explore the relationship between how breast cancer survivors think about cancer and how they manage the daily consequences of this disease, including its effects on identity. My main objective was to examine the cognitive strategies and social practices survivors employ for living with (a history of having had) cancer. Cancer experience is undoubtedly shaped by factors like disease stage and type, treatments received, time since diagnosis and treatment, age, and social location. But many of my participants, across categories, described bracketing some aspects of their experience while holding onto a certain degree of ontological insecurity as they redefined their lives after, with, or beyond cancer. Drawing on ontological insecurity enabled them to remain attuned to their selves: they used cancer to help them redraw boundaries in their lives and focus attention on their selves in ways they were not doing previously. While self-regulatory health practices, feminist ideologies/the women’s health movement, and environmental awareness overlap in breast cancer survivorship to produce activated patients and actualized subjectivities, my participants also discussed how the existential and medical uncertainties of their experiences led them to create new spaces for meaning in their lives. However, while many of my participants wanted to use cancer as a catalyst for self-growth or change across life domains, certainly not all of them were able to do so. Survivorship programs are critical in this regard. They can help survivors harness the uncertainty they feel instead of allowing it to become paralyzing or debilitating. Many survivors need help framing ontological insecurity as a resource to employ, not something to move beyond; but, moreover, they need spaces in which they can acknowledge these uncertainties as part of their new realities.

Advisors/Committee Members: Cerulo, Karen A (chair), Carr, Deborah (internal member), Horwitz, Allan (internal member), Almeling, Rene (outside member).

Subjects/Keywords: Breast – Cancer; Breast cancer patients; Cancer – Patients

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hemler, Jennifer R., 1. (2015). Life with, after, or beyond cancer: breast cancer survivorship and the new normal. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/48509/

Chicago Manual of Style (16^th Edition):

Hemler, Jennifer R., 1972-. “Life with, after, or beyond cancer: breast cancer survivorship and the new normal.” 2015. Doctoral Dissertation, Rutgers University. Accessed October 17, 2019. https://rucore.libraries.rutgers.edu/rutgers-lib/48509/.

MLA Handbook (7^th Edition):

Hemler, Jennifer R., 1972-. “Life with, after, or beyond cancer: breast cancer survivorship and the new normal.” 2015. Web. 17 Oct 2019.

Vancouver:

Hemler, Jennifer R. 1. Life with, after, or beyond cancer: breast cancer survivorship and the new normal. [Internet] [Doctoral dissertation]. Rutgers University; 2015. [cited 2019 Oct 17]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48509/.

Council of Science Editors:

Hemler, Jennifer R. 1. Life with, after, or beyond cancer: breast cancer survivorship and the new normal. [Doctoral Dissertation]. Rutgers University; 2015. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48509/

University of Zambia

18. Mukupo, Florence C. Breast self examination practices among rural (Solwezi) and urban (Lusaka) women .

Degree: 2012, University of Zambia

URL: http://hdl.handle.net/123456789/1445

► Breast cancer is a significant health threat for women and is currently the second- leading cause of cancer related deaths in women. Breast cancer is… (more)

▼ Breast cancer is a significant health threat for women and is currently the second- leading cause of cancer related deaths in women. Breast cancer is the second most common cancer of women in Zambia. Breast cancer screening has been shown to reduce mortality. Thus early detection is crucial. World Health Organization does not recommend mammography screening in developing countries because it is not cost effective. Breast Self Examination (BSE) is an alternative method of screening for breast cancer. BSE is recommended for all women over the age of 20. Despite this recommendation, adherence to BSE guidelines is quite low. Study Design The purpose of the current study was to compare knowledge and use of BSE among rural and urban women. The study also sought to detect associations between the study variables. Study Setting The study was conducted in Solwezi and Lusaka Districts. Sampling Simple random sampling was utilized to select the wards were the research was conducted. The using systematic sampling, households were selected. Then all women in childbearing age who met the inclusion criteria were interviewed. The age range was 15-49years because cancer of the breast has a high prevalence in this age group. A total of 238 respondents took part in the study. Instrument Data was collected using an interview schedule. Analysis Data analysis was done using EPI info statistical package. Results:The study showed that most of the respondents, 58.2% from urban area and 81.9% from rural area had no knowledge on breast cancer. The study also showed that BSE knowledge was low among the respondents. The majority of the respondents 84.5% in rural and 64.7% from urban area had no knowledge on BSE.BSE practice results showed that the majority of the respondents were not practicing BSE. The study concluded that both the knowledge and practice of BSE were low in both rural and urban areas.The study recommended that Primary health care workers should be trained to teach Breast self-examination (BSE). The MoH/CBoH should develop teaching manuals for use by health providers during BSE teaching so that there is consistence and uniformity in BSE information to the women. The MoH/CBoH should ensure that nurses' knowledge and skill in BSE should be improved through re-training so that they could give expert instructions to women in relation to BSE technique. Breast Awareness, which is advocated in place of routine breast examination, should be encouraged among women. Health providers should continue to initiate discussions on BSE and the importance of periodic check up that include Clinical Breast Examination (CBE) for all women.Women should be taught to request for CBE even if their initial visit has nothing to do with clinical breast examination. Nurses teaching BSE must emphasize that early detection and treatment enhances survival. School Health Programs should include health education on breast cancer and BSE so that these educational programs on BSE start as early as 12 years of age, so that the girl child could start BSE early and…

Subjects/Keywords: Breast – Examination; Breast – Cancer – Zambia

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APA (6^th Edition):

Mukupo, F. C. (2012). Breast self examination practices among rural (Solwezi) and urban (Lusaka) women . (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/1445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mukupo, Florence C. “Breast self examination practices among rural (Solwezi) and urban (Lusaka) women .” 2012. Thesis, University of Zambia. Accessed October 17, 2019. http://hdl.handle.net/123456789/1445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mukupo, Florence C. “Breast self examination practices among rural (Solwezi) and urban (Lusaka) women .” 2012. Web. 17 Oct 2019.

Vancouver:

Mukupo FC. Breast self examination practices among rural (Solwezi) and urban (Lusaka) women . [Internet] [Thesis]. University of Zambia; 2012. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/123456789/1445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mukupo FC. Breast self examination practices among rural (Solwezi) and urban (Lusaka) women . [Thesis]. University of Zambia; 2012. Available from: http://hdl.handle.net/123456789/1445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Southern California

19. Liu, Chia-Wei. Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study.

Degree: MS, Biostatistics, 2015, University of Southern California

URL: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/553067/rec/2733

► Background/Objective: This study was performed to compare the rates of breast reconstruction between a public safety‐net hospital (LA County Medical Center (LAC)) vs. a academic… (more)

▼ Background/Objective: This study was performed to compare the rates of breast reconstruction between a public safety‐net hospital (LA County Medical Center (LAC)) vs. a academic medical center (Keck Hospital of USC/Norris Cancer Center (Keck/Norris)), with emphasis on immediate breast reconstruction (IBR). We hypothesized that both overall reconstruction rate (the proportion of patients receiving reconstruction among the total patients having mastectomy) and the IBR rate (the proportion of patients receiving IBR among the total patients having reconstruction) were higher at Keck/Norris than LAC. We also aimed to explore the factors that were associated with overall reconstruction rate or IBR rate, and to estimate the time to reconstruction and the fraction of patients who would not undergo delayed breast reconstruction (cure fraction). ❧ Methods: We retrospectively collected all the data of patients with stage 0 – III breast cancer who received mastectomy during Jan 2006 to Dec 2013 from Keck/Norris and LAC. Univariate and multivariate logistic regressions were performed to compare the IBR rate and overall reconstruction rate between the two institutions, as well as to evaluate the correlation between IBR rate or overall reconstruction rate with various factors. Kaplan‐Meier method was used to scrutinize the time to reconstruction, and non‐mixture cure fraction model was performed for estimating the cure fraction. ❧ Results: Of the 453 patients, 327 patients were from LAC and 126 were from Keck/Norris. The odds ratio (OR) of reconstruction rate was 2.2 at Keck/Norris compared to LAC (p < 0.001) without adjustment for patient demographic factors, but was no longer significant with adjustment. The OR of IBR rate was 21.2 compared from Keck/Norris to LAC (p < 0.001) without adjustment for patient demographic factors, and was 22.3 with adjustment (p < 0.001). Based on the p < 0.25 entry criteria, factors that we kept in the multivariate overall reconstruction rate model were insurance status (p < 0.001), race (p < 0.05), age (p < 0.001), BMI (p < 0.05), smoking status (p = 0.08), occupation status (p = 0.18), personal history of other cancer (p = 0.12), progesterone receptor (PR) status (p = 0.22) and radiotherapy (p < 0.001). For IBR rate we had institution (p < 0.001), BMI (p = 0.21), clinical stage (p < 0.01) and radiotherapy (p < 0.01) in the model. The Kaplan‐Meier curves revealed that more patients underwent IBR at Keck/Norris than at LAC. Excluding the IBR patients, the average time to reconstruction at Keck/Norris was 20.3 ± 0.47 (SE) months, and was 37.4 ± 0.91 (SE) months at LAC. The estimated cure fractions were 0.71 and 0.99 at LAC and Keck/Norris, respectively. The factors that we kept in the multivariate non‐mixture cure fraction model were institution (p < 0.01), insurance status (p < 0.05), age = (p < 0.001), smoking status (p = 0.10), occupation status (p = 0.062), clinical stage (p = 0.12), PR status (p < 0.05). ❧ Conclusions: The reconstruction rate did not differ between these two institutions, but… Advisors/Committee Members: Sposto, Richard (Committee Chair), Mack, Wendy Jean (Committee Member), Groshen, Susan L. (Committee Member).

Subjects/Keywords: breast cancer; mastectomy; breast reconstruction

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APA (6^th Edition):

Liu, C. (2015). Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study. (Masters Thesis). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/553067/rec/2733

Chicago Manual of Style (16^th Edition):

Liu, Chia-Wei. “Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study.” 2015. Masters Thesis, University of Southern California. Accessed October 17, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/553067/rec/2733.

MLA Handbook (7^th Edition):

Liu, Chia-Wei. “Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study.” 2015. Web. 17 Oct 2019.

Vancouver:

Liu C. Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study. [Internet] [Masters thesis]. University of Southern California; 2015. [cited 2019 Oct 17]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/553067/rec/2733.

Council of Science Editors:

Liu C. Factors influencing the decision and timing to undergo breast reconstruction after mastectomy for breast cancer in public hospital vs. private medical center from 2007 to 2013: a retrospective cohort study. [Masters Thesis]. University of Southern California; 2015. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/553067/rec/2733

University of New South Wales

20. Kalyuga , Maria. Exploration of the role of the ETS transcription factor ESE2 in breast cancer.

Degree: Clinical School - St Vincent's Hospital, 2011, University of New South Wales

URL: http://handle.unsw.edu.au/1959.4/51251 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:9903/SOURCE02?view=true

► Thesis abstract: Breast cancer represents a leading cancer-related diagnosis of Australian women, with treatments ultimately still ineffective for many patients. Investigating the mechanisms behind normal… (more)

▼ Thesis abstract: Breast cancer represents a leading cancer-related diagnosis of Australian women, with treatments ultimately still ineffective for many patients. Investigating the mechanisms behind normal breast development is a means to identify processes involved in carcinogenesis, as they are frequently corrupted to facilitate tumour initiation and progression. The PRL signaling pathway is vital for the function of the mammary tissue during pregnancy and lactation. The mouse ELF5 and its human counterpart, ESE2, were identified as downstream targets of this pathway and have subsequently been characterised as crucial players in mammary gland development. In addition, limited evidence has pointed to the possibility of this protein being involved in human breast carcinogenesis, although a direct link remains pending. The current body of work was aimed at exploring the role of the human ESE2 in breast cancer. This was achieved through the use of a range of large and small-scale in vitro techniques to, firstly, attempt to identify potential ESE2 binding partners. Secondly, a model of inducible, stable ESE2 downregulation was employed to establish the function of ESE2 in the T47D breast cancer cell line, in the context of progesterone signaling, which is an important mediator of normal and aberrant mammary gland behaviour. It was determined that inhibiting a progestin-mediated ESE2 increase led to the augmentation of the previously characterised anti-proliferative effects of this hormone. An equivalent overexpression model was generated and characterised in detail. Negative effects of ESE2 on cell proliferation and adhesion were identified and were accompanied by changes at the level of apoptosis, gene transcription activity and other molecular changes. The data gathered is the first study to directly examine the role of ESE2 in human breast cancer. Advisors/Committee Members: Ormandy, Christopher , Clinical School - St Vincent's Hospital, Faculty of Medicine, UNSW.

Subjects/Keywords: Breast cancer; Human breast carcinogenesis

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APA (6^th Edition):

Kalyuga , M. (2011). Exploration of the role of the ETS transcription factor ESE2 in breast cancer. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/51251 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:9903/SOURCE02?view=true

Chicago Manual of Style (16^th Edition):

Kalyuga , Maria. “Exploration of the role of the ETS transcription factor ESE2 in breast cancer.” 2011. Doctoral Dissertation, University of New South Wales. Accessed October 17, 2019. http://handle.unsw.edu.au/1959.4/51251 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:9903/SOURCE02?view=true.

MLA Handbook (7^th Edition):

Kalyuga , Maria. “Exploration of the role of the ETS transcription factor ESE2 in breast cancer.” 2011. Web. 17 Oct 2019.

Vancouver:

Kalyuga M. Exploration of the role of the ETS transcription factor ESE2 in breast cancer. [Internet] [Doctoral dissertation]. University of New South Wales; 2011. [cited 2019 Oct 17]. Available from: http://handle.unsw.edu.au/1959.4/51251 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:9903/SOURCE02?view=true.

Council of Science Editors:

Kalyuga M. Exploration of the role of the ETS transcription factor ESE2 in breast cancer. [Doctoral Dissertation]. University of New South Wales; 2011. Available from: http://handle.unsw.edu.au/1959.4/51251 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:9903/SOURCE02?view=true

Western Carolina University

21. Ma, Yiming. A novel shape feature to classify microcalcifications.

Degree: 2010, Western Carolina University

URL: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=7827

► Clinical evident shows that the shape of mammographic calcification is an indicator of the pathology. Microcalcifications (MC) with rough shape are early signs of malignant… (more)

Subjects/Keywords: Breast – Cancer – Diagnosis; Breast – Radiography; Breast – Imaging

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APA (6^th Edition):

Ma, Y. (2010). A novel shape feature to classify microcalcifications. (Masters Thesis). Western Carolina University. Retrieved from http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=7827

Chicago Manual of Style (16^th Edition):

Ma, Yiming. “A novel shape feature to classify microcalcifications.” 2010. Masters Thesis, Western Carolina University. Accessed October 17, 2019. http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=7827.

MLA Handbook (7^th Edition):

Ma, Yiming. “A novel shape feature to classify microcalcifications.” 2010. Web. 17 Oct 2019.

Vancouver:

Ma Y. A novel shape feature to classify microcalcifications. [Internet] [Masters thesis]. Western Carolina University; 2010. [cited 2019 Oct 17]. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=7827.

Council of Science Editors:

Ma Y. A novel shape feature to classify microcalcifications. [Masters Thesis]. Western Carolina University; 2010. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=7827

Oregon State University

22. Everson, Courtney Louise. Reproductive decision-making in young women breast cancer survivors.

Degree: MA, Applied Anthropology, 2009, Oregon State University

URL: http://hdl.handle.net/1957/10010

► The purpose of this study is to use an integrated biocultural perspective to examine the decision-making processes of young survivors as they navigate breast cancer… (more)

Subjects/Keywords: breast cancer; Breast – Cancer – Patients – Decision making

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APA (6^th Edition):

Everson, C. L. (2009). Reproductive decision-making in young women breast cancer survivors. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/10010

Chicago Manual of Style (16^th Edition):

Everson, Courtney Louise. “Reproductive decision-making in young women breast cancer survivors.” 2009. Masters Thesis, Oregon State University. Accessed October 17, 2019. http://hdl.handle.net/1957/10010.

MLA Handbook (7^th Edition):

Everson, Courtney Louise. “Reproductive decision-making in young women breast cancer survivors.” 2009. Web. 17 Oct 2019.

Vancouver:

Everson CL. Reproductive decision-making in young women breast cancer survivors. [Internet] [Masters thesis]. Oregon State University; 2009. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/1957/10010.

Council of Science Editors:

Everson CL. Reproductive decision-making in young women breast cancer survivors. [Masters Thesis]. Oregon State University; 2009. Available from: http://hdl.handle.net/1957/10010

University of Hong Kong

23. 譚思琪; Tam, Sze-ki, Melanie. Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study.

Degree: Master of Medical Sciences, 2016, University of Hong Kong

URL: http://hdl.handle.net/10722/237219

►

Neoadjuvant chemotherapy (NACT) has been shown to facilitate surgery through downsizing inoperable tumours to operable or reducing mastectomy-required tumours to make it treatable by breast… (more)

▼

Neoadjuvant chemotherapy (NACT) has been shown to facilitate surgery through downsizing inoperable tumours to operable or reducing mastectomy-required tumours to make it treatable by breast conserving surgery (BCT), preserving more breast tissue. Chinese patients can benefit immensely from BCT due to their relatively small breast size. Currently, BCT rate and its clinical outcome after neoadjuvant therapy are understudied in Hong Kong. Most NACT studies done in the West only look at the total number of BCT attempted and neglect the initial surgical assignment of the subjects. With the use of targeted therapy alongside with chemotherapy, many patients are able to significantly downsize their tumours for BCT. As a matter of fact, the rate of pathological complete response has improved drastically since the development of targeted therapy, however, BCT rate has remained more or less unchanged. Studying surgical assignment before and after NACT can help identifying the underlying causes of this phenomenon. Our study aims (1) to investigate BCT assignment conversion rate from mastectomy (MX) to BCT, (2) to study the rate of BCT with tumour-free margins, (3) to examine the correlation between pCR and BCT assignment, and (4) to compare clinical outcomes between MX and BCT. Data is retrieved from a prospectively built database and retrospectively analyzed. Patients who were diagnosed with invasive carcinoma of stage I to III who received NACT and underwent surgery between January 2000 and December 2014 at the Department of Surgery, University of Hong Kong Li Ka Shing Faculty of Medicine were included in this study. Patients’ characteristics, including their demographics, tumour characteristics, response to neoadjuvant therapy, and treatment details and information of their follow-ups were extracted from the database. Our findings revealed that MX was preferred to BCT in our study population even though similar recurrence rate and survival outcome could be achieved in both surgical methods after NACT. Advanced disease was found to be one of the major reasons why MX was preferred. Detailed and elaborated information about the surgical assignment by doctors and patients’ preferences, if it is available, will greatly enhanced the quality of this study.

published_or_final_version

Surgery

Master

Master of Medical Sciences

Subjects/Keywords: Breast - Cancer - Surgery; Breast - Cancer - Adjuvant treatment

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APA (6^th Edition):

譚思琪; Tam, Sze-ki, M. (2016). Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study. (Masters Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/237219

Chicago Manual of Style (16^th Edition):

譚思琪; Tam, Sze-ki, Melanie. “Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study.” 2016. Masters Thesis, University of Hong Kong. Accessed October 17, 2019. http://hdl.handle.net/10722/237219.

MLA Handbook (7^th Edition):

譚思琪; Tam, Sze-ki, Melanie. “Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study.” 2016. Web. 17 Oct 2019.

Vancouver:

譚思琪; Tam, Sze-ki M. Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study. [Internet] [Masters thesis]. University of Hong Kong; 2016. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10722/237219.

Council of Science Editors:

譚思琪; Tam, Sze-ki M. Breast conserving therapy(BCT) and its clinical outcome after neoadjuvant chemotherapy in Hong Kong : a single-centre retrospective cohort study. [Masters Thesis]. University of Hong Kong; 2016. Available from: http://hdl.handle.net/10722/237219

University of the Western Cape

24. Janodien, Fatima. Proteome signature of breast cancer cells treated with fucoidan .

Degree: 2016, University of the Western Cape

URL: http://hdl.handle.net/11394/5315

► Breast cancer is responsible for a large portion of cancer-related deaths. Worldwide, incidence is increasing. Routinely-used treatments for breast cancer are invasive and are associated… (more)

Subjects/Keywords: Breast – Cancer – Treatment; Breast cancer; Fucoidan

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APA (6^th Edition):

Janodien, F. (2016). Proteome signature of breast cancer cells treated with fucoidan . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/5315

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Janodien, Fatima. “Proteome signature of breast cancer cells treated with fucoidan .” 2016. Thesis, University of the Western Cape. Accessed October 17, 2019. http://hdl.handle.net/11394/5315.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Janodien, Fatima. “Proteome signature of breast cancer cells treated with fucoidan .” 2016. Web. 17 Oct 2019.

Vancouver:

Janodien F. Proteome signature of breast cancer cells treated with fucoidan . [Internet] [Thesis]. University of the Western Cape; 2016. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/11394/5315.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Janodien F. Proteome signature of breast cancer cells treated with fucoidan . [Thesis]. University of the Western Cape; 2016. Available from: http://hdl.handle.net/11394/5315

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Columbia University

25. Putcha, Preeti. HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers.

Degree: 2015, Columbia University

URL: https://doi.org/10.7916/D81835KX

► Inflammatory Breast Cancer (IBC) is a rare, lethal, and understudied form of breast cancer. Although affecting 1-2% of the population, the remission rate is half… (more)

Subjects/Keywords: Pathology; Cytology; Breast – Cancer; Breast – Cancer – Treatment

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APA (6^th Edition):

Putcha, P. (2015). HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D81835KX

Chicago Manual of Style (16^th Edition):

Putcha, Preeti. “HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers.” 2015. Doctoral Dissertation, Columbia University. Accessed October 17, 2019. https://doi.org/10.7916/D81835KX.

MLA Handbook (7^th Edition):

Putcha, Preeti. “HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers.” 2015. Web. 17 Oct 2019.

Vancouver:

Putcha P. HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers. [Internet] [Doctoral dissertation]. Columbia University; 2015. [cited 2019 Oct 17]. Available from: https://doi.org/10.7916/D81835KX.

Council of Science Editors:

Putcha P. HDAC6 as a novel candidate in the treatment of Inflammatory Breast Cancers. [Doctoral Dissertation]. Columbia University; 2015. Available from: https://doi.org/10.7916/D81835KX

University of Johannesburg

26. Minnaar, Carrie-Anne. The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment.

Degree: 2010, University of Johannesburg

URL: http://hdl.handle.net/10210/3161

►

M. Tech.

AIM: To determine the efficacy of Astragalus membranaceous tincture at maintaining the circulating white blood cell count (WBC) and absolute neutrophil count (ANC)… (more)

Subjects/Keywords: Breast cancer chemotherapy; Breast cancer treatment

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APA (6^th Edition):

Minnaar, C. (2010). The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/3161

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Minnaar, Carrie-Anne. “The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment.” 2010. Thesis, University of Johannesburg. Accessed October 17, 2019. http://hdl.handle.net/10210/3161.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Minnaar, Carrie-Anne. “The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment.” 2010. Web. 17 Oct 2019.

Vancouver:

Minnaar C. The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment. [Internet] [Thesis]. University of Johannesburg; 2010. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10210/3161.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Minnaar C. The efficacy of astragalus membranaceous tincture at maintaining the circulating leucocyte and absolute neutrophil counts of breast cancer patients undergoing chemotherapeutic treatment. [Thesis]. University of Johannesburg; 2010. Available from: http://hdl.handle.net/10210/3161

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Boston University

27. Lee, Tian Yu. The role and function of SOX11 in DNA damage in triple-negative breast cancer.

Degree: MS, Medical Sciences, 2019, Boston University

URL: http://hdl.handle.net/2144/36570

► Breast cancer is a complex heterogenous disease that consists of several different subtypes displaying distinct behaviors and responses to different treatments. It is the second… (more)

Subjects/Keywords: Oncology; Breast cancer; Triple-negative breast cancer

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APA (6^th Edition):

Lee, T. Y. (2019). The role and function of SOX11 in DNA damage in triple-negative breast cancer. (Masters Thesis). Boston University. Retrieved from http://hdl.handle.net/2144/36570

Chicago Manual of Style (16^th Edition):

Lee, Tian Yu. “The role and function of SOX11 in DNA damage in triple-negative breast cancer.” 2019. Masters Thesis, Boston University. Accessed October 17, 2019. http://hdl.handle.net/2144/36570.

MLA Handbook (7^th Edition):

Lee, Tian Yu. “The role and function of SOX11 in DNA damage in triple-negative breast cancer.” 2019. Web. 17 Oct 2019.

Vancouver:

Lee TY. The role and function of SOX11 in DNA damage in triple-negative breast cancer. [Internet] [Masters thesis]. Boston University; 2019. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/2144/36570.

Council of Science Editors:

Lee TY. The role and function of SOX11 in DNA damage in triple-negative breast cancer. [Masters Thesis]. Boston University; 2019. Available from: http://hdl.handle.net/2144/36570

University of Namibia

28. Mowa, AK. An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek .

Degree: 2016, University of Namibia

URL: http://hdl.handle.net/11070/1853

► An alarming increase of breast cancer in Namibia started in 2005 with a record of 179 cases, and 1625 cases in 2006 respectively. To date,… (more)

▼ An alarming increase of breast cancer in Namibia started in 2005 with a record of 179 cases, and 1625 cases in 2006 respectively. To date, the cancer Association of Namibia (CAN) as a registry reported 3092 cancer incidences in 2012. The purpose of this study is to explore the Knowledge, Attitudes and Practices (KAP) and the correlation of the determinant factors on early detection of bread cancer among women in Windhoek. Methods used were the purposive sampling involving 236 women and simple random sampling for selecting six (6) health care facilities in Windhoek, Khomas region. The data collection was conducted over a period of three months, commencing in May 2015 and ended 31st July 2015. A structured questionnaire was used to interview 236 women. The questionnaire consisted of four sections such as Demography, Knowledge, Attitudes and Practice, cross tabulated with variables such as Age, Employment and Educational status. The data were analyzed by using the Statistical Package for Social Science (SPSS) software. The findings indicated that 78.8 % of women had knowledge on breast cancer and early detection, whereas 21.2% lacked the knowledge. The question about sources of information regarding breast cancer yielded the following, clinics recorded 34%, while Television (TV) and radio media with 32.7%. These sources were found to have played the biggest role in information sharing. Women with secondary education (64.5%) were more knowledgeable, followed by those with tertiary levels (29.5%). The age categories of 21-30 and 31- 40 indicated a sum of 46.8% to have knowledge on breast cancer. Attitudes among women on breast cancer practices, multiple responses were given. 92.5% responded that they would consult a Doctor, while 87.6% would be scared about the disease. Fewer responses came from women who wished to consult the traditional healers and prayer house (9.1% and 1.1%) respectively. About 90.5% of women happen to have medical insurance cover whereas 59.0% have no medical insurance cover. About 63% of women have practiced mammogram, while about 31% did not practice the mammogram screening. Employed women and student/ learners (83.3%), reported to be practicing mammogram, while 75.6% of the unemployed didn’t practice mammogram. Age categories of 21-30 and 41-49 recorded 72.1% and 66.7% respectively in practicing mammogram. The use of Clinical Breast Examination recorded a small fraction among respondents as only 27.5% visited the health facilities/ doctor for breast examination, while 72.5% were the women who did not seek any medical or visited the doctor for any clinical breast examination. In conclusion; even though the study findings revealed that the majority of women in Windhoek have a sound knowledge of breast cancer, there are still some negative attitudes towards the screenings and practices as stated in the problem statement that there is an alarming increase of breast cancer in Namibia, therefore the study recommends that, the Ministry of Health and Social Services in collaboration with the Cancer…

Subjects/Keywords: Breast cancer ; Breast, Cancer, Genetic aspects ; Breast, Cancer, Social aspects ; Breast, Cancer, Research

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mowa, A. (2016). An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek . (Thesis). University of Namibia. Retrieved from http://hdl.handle.net/11070/1853

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mowa, AK. “An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek .” 2016. Thesis, University of Namibia. Accessed October 17, 2019. http://hdl.handle.net/11070/1853.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mowa, AK. “An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek .” 2016. Web. 17 Oct 2019.

Vancouver:

Mowa A. An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek . [Internet] [Thesis]. University of Namibia; 2016. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/11070/1853.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mowa A. An exploration of knowledge, attitudes and practices and other breast cancer determinants influencing early detection among women in WIndhoek . [Thesis]. University of Namibia; 2016. Available from: http://hdl.handle.net/11070/1853

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Utah

29. Wujcik, Debra M. Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program.

Degree: PhD, Nursing;, 2007, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/2068/rec/916

► Breast cancer (BC) remains the most common cancer in women. Although screening mammography (SM) is an effective approach for early detection of BC, uninsured, underinsured,… (more)

▼ Breast cancer (BC) remains the most common cancer in women. Although screening mammography (SM) is an effective approach for early detection of BC, uninsured, underinsured, and minority women often do not have access to SM. The National Breast and Cervical Early Detection Program provide free access to SM. Of women who screen, 10-15% requires further testing, and half of those delay or do not return. Delay may contribute to later stage BC at diagnosis and increased rates of recurrence and death. This study was conducted to identify predictors of delay after an abnormal mammogram and predictors of rescreening behavior in women enrolled in the Tennessee Breast and Cervical Screening Program. Bivariate and multivariate logistic regression analyses were used to explore association between age, race, ethnicity, and marital status, BC history, and presence of breast symptoms and the outcomes of delay and rescreening behavior. Of 11,610 women, 37% required further testing. In a subset of women with time to completion > 1 day, 30% experienced delay > two months. Seventeen percent had another SM during the study period (2002-2006). The high percentage of women needing further testing is likely attributed to the program receiving referrals for diagnosis of symptomatic women as well as asymptomatic screening. Controlling for marital status, age, and BC history, there was more delay in test completion if the women African American versus Caucasian (OR 1.45, 95% CI 1.13, 1.85), Hispanic (OR .72, 95% CI 0.55, 0.93) and reported no breast symptoms (OR 1.50, 95% CI 1.27, 1.77). A delay in receipts of test results > 1 week contributed to the overall delay. Controlling for race and BC history, there was greater likelihood of rescreening if the women were married (OR 1.27, 95% CI 1.12, 1.43) and over 50 years of age (OR 1.92, 95% CI 1.67, 2.21) and less likelihood if the women were non-Hispanic (OR 0.71, 95% CI 0.60, 0.83) and had no breast symptoms (OR 0.85, 95% CI 0.76.,0.96). Findings can be used to identify women at risk for delay, assess understanding of the indication for further test, identify potential barriers to completion of testing or rescreening, and tailor interventions to overcome the barriers.

Subjects/Keywords: Breast Cancer; Health

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wujcik, D. M. (2007). Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/2068/rec/916

Chicago Manual of Style (16^th Edition):

Wujcik, Debra M. “Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program.” 2007. Doctoral Dissertation, University of Utah. Accessed October 17, 2019. http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/2068/rec/916.

MLA Handbook (7^th Edition):

Wujcik, Debra M. “Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program.” 2007. Web. 17 Oct 2019.

Vancouver:

Wujcik DM. Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program. [Internet] [Doctoral dissertation]. University of Utah; 2007. [cited 2019 Oct 17]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/2068/rec/916.

Council of Science Editors:

Wujcik DM. Predictors of delay in resolution after mammography and rescreening behaviors in a state cancer screening program. [Doctoral Dissertation]. University of Utah; 2007. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd2/id/2068/rec/916

California State University – East Bay

30. Agarwal, Aditi. Development of Organotypic Human Breast Cell Cultures for High Throughput Testing.

Degree: 2014, California State University – East Bay

URL: http://hdl.handle.net/10211.3/119073

► The long-term goal of this study was to develop a reproducible physiologically relevant, normal human breast tissue culture system that supports the morphological characteristics, cell… (more)

Subjects/Keywords: Breast – Cancer – Research

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Agarwal, A. (2014). Development of Organotypic Human Breast Cell Cultures for High Throughput Testing. (Thesis). California State University – East Bay. Retrieved from http://hdl.handle.net/10211.3/119073

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Agarwal, Aditi. “Development of Organotypic Human Breast Cell Cultures for High Throughput Testing.” 2014. Thesis, California State University – East Bay. Accessed October 17, 2019. http://hdl.handle.net/10211.3/119073.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Agarwal, Aditi. “Development of Organotypic Human Breast Cell Cultures for High Throughput Testing.” 2014. Web. 17 Oct 2019.

Vancouver:

Agarwal A. Development of Organotypic Human Breast Cell Cultures for High Throughput Testing. [Internet] [Thesis]. California State University – East Bay; 2014. [cited 2019 Oct 17]. Available from: http://hdl.handle.net/10211.3/119073.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Agarwal A. Development of Organotypic Human Breast Cell Cultures for High Throughput Testing. [Thesis]. California State University – East Bay; 2014. Available from: http://hdl.handle.net/10211.3/119073

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations