subject:(Blood vessels)

University of Illinois – Chicago

1. Hsu, Chih-Yang. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.

Degree: 2017, University of Illinois – Chicago

► There is a fundamental gap in how blood flow quantification can be accomplished in interventional digital subtraction angiography (DSA) to provide physicians with measurements to… (more)

▼ There is a fundamental gap in how blood flow quantification can be accomplished in interventional digital subtraction angiography (DSA) to provide physicians with measurements to interpret the patient’s vascular health. Continued existence of this gap represents an important problem because, until it is filled, physicians can only rely on qualitative information of intensity changes to understand blood flow variations caused by the intervention treatment. The long-term goal is to transform DSA, the gold standard for qualitative blood flow assessment, into a fully automated quantitative measurement tool that can potentially aid clinical decision making in endovascular interventions. Current approaches focus on using signals from a single vessel to determine blood flow and have not been successful due to the slow frame rate. It is our central hypothesis that a radically different flow quantification approach, using all the information from the entire image set concurrently to overcome the slow DSA frame rate, will provide reliable blood flow measurement in all vessels. The immediate objective is to create the proposed whole-tree DSA blood flow measurement method and to test its feasibility and accuracy. Success here would justify a future clinical trial of DSA-based flow measurement. The results of our study will be used to determine whether our global approach can provide reliable flow quantification in a clinical situation. The approach is innovative, because it uses global information to reliably measurement the blood flow rate in DSA. The proposed research is significant, because it is expected to rapidly produce reliable flow measurements in all visible vessels to facilitate physician’s understanding of patient’s vascular status. The novel technique will gap the bridge between the large arteries and micro vessels, providing flow measurements in all visible vessels that can be used to study cerebral hemodynamics. Ultimately, such technique has the potential to alternate clinical decision making for better treatment prognosis to reduce healthcare cost in treating cerebral vascular diseases. Advisors/Committee Members: Linninger, Andreas (advisor), Diwekar, Urmila (committee member), Zhou, Xiaohong (committee member), Magin, Richard (committee member), Alaraj, Ali (committee member), Linninger, Andreas (chair).

Subjects/Keywords: Blood vessels; blood flow

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APA (6^th Edition):

Hsu, C. (2017). Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21822

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hsu, Chih-Yang. “Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.” 2017. Thesis, University of Illinois – Chicago. Accessed April 10, 2021. http://hdl.handle.net/10027/21822.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hsu, Chih-Yang. “Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.” 2017. Web. 10 Apr 2021.

Vancouver:

Hsu C. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. [Internet] [Thesis]. University of Illinois – Chicago; 2017. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10027/21822.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hsu C. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. [Thesis]. University of Illinois – Chicago; 2017. Available from: http://hdl.handle.net/10027/21822

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Uhernik, Amy Lynn. Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells.

Degree: MS(M.S.), Biology, 2018, Colorado State University – Pueblo

URL: http://hdl.handle.net/10217/187636

► In this thesis, we describe different mechanisms of regulating and controlling MCT1 (Monocarboxylic Acid Transporte 1) function in rat brain endothelial cells. This work provides… (more)

Subjects/Keywords: Endothelium; Blood-vessels; Cerebrovascular disease

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APA (6^th Edition):

Uhernik, A. L. (2018). Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells. (Masters Thesis). Colorado State University – Pueblo. Retrieved from http://hdl.handle.net/10217/187636

Chicago Manual of Style (16^th Edition):

Uhernik, Amy Lynn. “Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells.” 2018. Masters Thesis, Colorado State University – Pueblo. Accessed April 10, 2021. http://hdl.handle.net/10217/187636.

MLA Handbook (7^th Edition):

Uhernik, Amy Lynn. “Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells.” 2018. Web. 10 Apr 2021.

Vancouver:

Uhernik AL. Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells. [Internet] [Masters thesis]. Colorado State University – Pueblo; 2018. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10217/187636.

Council of Science Editors:

Uhernik AL. Control and regulation of MCT1 function by intracellular pH and cAMP analogs in cerebrovascular endothelial cells. [Masters Thesis]. Colorado State University – Pueblo; 2018. Available from: http://hdl.handle.net/10217/187636

University of Bridgeport

3. Yildirim, Burak. Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm .

Degree: 2019, University of Bridgeport

URL: https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4024

► In this work, a rule-based method is presented for blood vessel segmentation in digital retinal images. This method can be used in computer analyses of… (more)

Subjects/Keywords: Retinal blood vessels; Fuzzy logic

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APA (6^th Edition):

Yildirim, B. (2019). Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm . (Thesis). University of Bridgeport. Retrieved from https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4024

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yildirim, Burak. “Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm .” 2019. Thesis, University of Bridgeport. Accessed April 10, 2021. https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4024.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yildirim, Burak. “Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm .” 2019. Web. 10 Apr 2021.

Vancouver:

Yildirim B. Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm . [Internet] [Thesis]. University of Bridgeport; 2019. [cited 2021 Apr 10]. Available from: https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4024.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yildirim B. Segmentation Of Retinal Blood Vessels Using A Novel Fuzzy Logic Algorithm . [Thesis]. University of Bridgeport; 2019. Available from: https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4024

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Stellenbosch University

4. Cilliers, Karen. Description of the cerebral vasculature in a southern African cadaver cohort.

Degree: MSc, Biomedical Sciences, 2016, Stellenbosch University

URL: http://hdl.handle.net/10019.1/98572

► ENGLISH ABSTRACT: Few studies give a complete description on the origin, absence, duplication and triplication of the cerebral cortical branches. The anterior cerebral artery (ACA)… (more)

▼ ENGLISH ABSTRACT: Few studies give a complete description on the origin, absence, duplication and triplication of the cerebral cortical branches. The anterior cerebral artery (ACA) varies considerably and this complicates the description of the normal anatomy. The most commonly discussed branching types of the middle cerebral artery (MCA) include bifurcation and trifurcation. Branching of the posterior cerebral artery (PCA) has not been adequately described; only the division level of the parieto-occipital (PoA) and calcarine arteries has been discussed. Anomalies of the cerebral arteries have been reported. To the author’s best knowledge, no previous studies have investigated the anatomy of the cerebral arteries in a Western Cape population. Therefore, the aim of this study is to describe the anatomy and anomalies of the cerebral vasculature in a Southern African cadaver cohort. Twenty hemispheres were used for the pilot study and 126 hemispheres for the present study. These 126 hemispheres consisted of 88 males and 38 females, between the ages of 22 and 84. Specimens were distributed over three population groups, namely, coloured (n=76), black (n=38), white (n=10) and unknown (n=2). The arteries were injected with coloured silicone. The external diameter and length of all the cortical branches of the cerebral arteries were measured using a digital micrometre. The diameter and lengths indicated statistically significant differences on the right and left side, between males and females, different population groups and different age groups. The most commonly absent artery was the callosomarginal artery, and the most commonly duplicated artery was the paracentral lobule artery. The origin of the cortical branches was similar to the descriptions in the literature; however, the common trunks and unusual origins were also noted. The branching pattern of the MCA was classified according to the 11 different subtypes described in the literature. Medial bifurcation was most commonly observed. The branching pattern of the PCA was assessed, and in most cases there was additional branching before the division of the calcarine artery and PoA. Anomalies observed in the present study included bihemispheric ACA (19.8%), median ACA (11.6%) and fenestration of the PCA (1.6%). The only anomaly observed in the pilot study was fenestration of the PCA (5.0%). A shorter trunk may play a role in aneurysm formation, and changes in vessel diameter could indicate early signs of several pathological conditions. Aneurysms can be observed at the branching of cerebral vessels, highlighting the importance of a thorough knowledge of the vascular anatomy. The MCA branching subtypes were described, since only bifurcation and trifurcation are usually noted. Furthermore, the branching pattern of the PCA has not been adequately described in previous reports; therefore the possible branching types were defined. Anomalies of the cerebral arteries are usually only mentioned; therefore the bihemispheric and median ACA were fully described (origin, length,… Advisors/Committee Members: Page, Benedict, Stellenbosch University. Faculty of Medicine and Health Sciences. Dept. of Biomedical Sciences. Anatomy and Histology..

Subjects/Keywords: UCTD; Brain – Blood-vessels – Anatomy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Cilliers, K. (2016). Description of the cerebral vasculature in a southern African cadaver cohort. (Masters Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/98572

Chicago Manual of Style (16^th Edition):

Cilliers, Karen. “Description of the cerebral vasculature in a southern African cadaver cohort.” 2016. Masters Thesis, Stellenbosch University. Accessed April 10, 2021. http://hdl.handle.net/10019.1/98572.

MLA Handbook (7^th Edition):

Cilliers, Karen. “Description of the cerebral vasculature in a southern African cadaver cohort.” 2016. Web. 10 Apr 2021.

Vancouver:

Cilliers K. Description of the cerebral vasculature in a southern African cadaver cohort. [Internet] [Masters thesis]. Stellenbosch University; 2016. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10019.1/98572.

Council of Science Editors:

Cilliers K. Description of the cerebral vasculature in a southern African cadaver cohort. [Masters Thesis]. Stellenbosch University; 2016. Available from: http://hdl.handle.net/10019.1/98572

Brock University

5. Goswami, Ruma. Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? .

Degree: Applied Health Sciences Program, 2006, Brock University

URL: http://hdl.handle.net/10464/1537

► Although medium sized, muscular vessels normally respond to sympathetic stimulation by reducing compliance, it is unclear whether the large brachial artery is similarly affected by… (more)

Subjects/Keywords: Arm; Blood-vessels; Blood-vessels

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APA (6^th Edition):

Goswami, R. (2006). Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? . (Thesis). Brock University. Retrieved from http://hdl.handle.net/10464/1537

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Goswami, Ruma. “Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? .” 2006. Thesis, Brock University. Accessed April 10, 2021. http://hdl.handle.net/10464/1537.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Goswami, Ruma. “Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? .” 2006. Web. 10 Apr 2021.

Vancouver:

Goswami R. Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? . [Internet] [Thesis]. Brock University; 2006. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10464/1537.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Goswami R. Does altering brachial artery tone with lower-body negative pressure and flow-mediated dilation affect arterial stiffness? . [Thesis]. Brock University; 2006. Available from: http://hdl.handle.net/10464/1537

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Utah

6. Chapman, Brian Earl. Comparison of image quality measures in cerebral magnetic resonance angiography;.

Degree: PhD, Biomedical Informatics;, 1998, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/67/rec/189

► Magnetic resonance angiography (MRA) is a less expensive and less invasive alternative to conventional x-ray angiography in the imaging of the cerebral vasculature. However, x-ray… (more)

▼ Magnetic resonance angiography (MRA) is a less expensive and less invasive alternative to conventional x-ray angiography in the imaging of the cerebral vasculature. However, x-ray angiography (XRA) provides better detail of small cerebral vessels than that currently obtainable with MRA. At the University of Utah a large research effort is directed towards improving MRA's depiction of the small cerebral vasculature. An important element in this research is a measure of image quality. This dissertation addressed the development of image quality measures for cerebral MRA. In this dissertation image quality was defined in terms of observer ability to detect segments of cerebral arteries. This detection was quantified using a two alternative forced choice experiment. The experiment used x-ray angiography images as a truth standard for defining the size, location, and orientation of the cerebral vasculature. It examined whether the two alternative forced choice results could be predicted by intrinsic image measures (i.e., signal-difference-to-noise ratio, contrast, and signal-difference-to-background-variation ratio) or by a ranking experiment where an observer qualitatively ranked the vasculature depicted in regions-of-interest within the images. These evaluation measures were applied to four imaging effects: (1) decreasing the receiver bandwidth for MR acquisition, (2) using magnetization transfer to reduce background tissue signal, (3) using zero-filled interpolation to improve display of the vasculature information, and (4) using phase constrained reconstruction techniques to reconstruct the MR angiography data. The intrinsic image measures and ranking measures did not strongly predict which effects significantly improved image quality defined by the two alternative forced choice. Only in the analysis of the magnetization transfer and zero-filled interpolation effects were all measures in agreement. When examined locally at the regions-of-interest, all the measures were found to be weakly predictive of each other, suggesting that all measures used common information and that each test was also sensitive to different additional information. The two alternative forced choice and ranking results were in closest agreement with contrast measurements, suggesting that these data were not primarily noise limited. The two alternative forced choice and ranking results were both sensitive to misregistration between the x-ray angiography images and the magnetic resonance angiography images and to the presence of additional vessels within the regions-of-interest. To increase confidence in the two alternative forced choice measure misregistration and signal ambiguity problems need to be corrected.

Subjects/Keywords: Brain; Blood Vessels

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APA (6^th Edition):

Chapman, B. E. (1998). Comparison of image quality measures in cerebral magnetic resonance angiography;. (Doctoral Dissertation). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/67/rec/189

Chicago Manual of Style (16^th Edition):

Chapman, Brian Earl. “Comparison of image quality measures in cerebral magnetic resonance angiography;.” 1998. Doctoral Dissertation, University of Utah. Accessed April 10, 2021. http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/67/rec/189.

MLA Handbook (7^th Edition):

Chapman, Brian Earl. “Comparison of image quality measures in cerebral magnetic resonance angiography;.” 1998. Web. 10 Apr 2021.

Vancouver:

Chapman BE. Comparison of image quality measures in cerebral magnetic resonance angiography;. [Internet] [Doctoral dissertation]. University of Utah; 1998. [cited 2021 Apr 10]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/67/rec/189.

Council of Science Editors:

Chapman BE. Comparison of image quality measures in cerebral magnetic resonance angiography;. [Doctoral Dissertation]. University of Utah; 1998. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/67/rec/189

University of Hong Kong

7. Chan, Yap-hang. Role of phytoestrogen in vascular function and dysfunction.

Degree: 2008, University of Hong Kong

URL: http://hdl.handle.net/10722/52128

Subjects/Keywords: Blood-vessels.; Phytoestrogens.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chan, Y. (2008). Role of phytoestrogen in vascular function and dysfunction. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/52128

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chan, Yap-hang. “Role of phytoestrogen in vascular function and dysfunction.” 2008. Thesis, University of Hong Kong. Accessed April 10, 2021. http://hdl.handle.net/10722/52128.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chan, Yap-hang. “Role of phytoestrogen in vascular function and dysfunction.” 2008. Web. 10 Apr 2021.

Vancouver:

Chan Y. Role of phytoestrogen in vascular function and dysfunction. [Internet] [Thesis]. University of Hong Kong; 2008. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10722/52128.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chan Y. Role of phytoestrogen in vascular function and dysfunction. [Thesis]. University of Hong Kong; 2008. Available from: http://hdl.handle.net/10722/52128

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

8. Wong, Ching-yuen. Impact of diet on vascular function in patients with type II diabetes mellitus.

Degree: 2009, University of Hong Kong

URL: http://hdl.handle.net/10722/56780

Subjects/Keywords: Diabetes.; Blood-vessels.

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APA (6^th Edition):

Wong, C. (2009). Impact of diet on vascular function in patients with type II diabetes mellitus. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/56780

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wong, Ching-yuen. “Impact of diet on vascular function in patients with type II diabetes mellitus.” 2009. Thesis, University of Hong Kong. Accessed April 10, 2021. http://hdl.handle.net/10722/56780.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wong, Ching-yuen. “Impact of diet on vascular function in patients with type II diabetes mellitus.” 2009. Web. 10 Apr 2021.

Vancouver:

Wong C. Impact of diet on vascular function in patients with type II diabetes mellitus. [Internet] [Thesis]. University of Hong Kong; 2009. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10722/56780.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wong C. Impact of diet on vascular function in patients with type II diabetes mellitus. [Thesis]. University of Hong Kong; 2009. Available from: http://hdl.handle.net/10722/56780

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

9. Chen, Areana Yen. The role of the spleen in regulation of extracellular fluid in the rat.

Degree: MS, Department of Medicine, 1995, University of Alberta

URL: https://era.library.ualberta.ca/files/2r36v142r

Subjects/Keywords: Spleen – Blood-vessels.

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APA (6^th Edition):

Chen, A. Y. (1995). The role of the spleen in regulation of extracellular fluid in the rat. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/2r36v142r

Chicago Manual of Style (16^th Edition):

Chen, Areana Yen. “The role of the spleen in regulation of extracellular fluid in the rat.” 1995. Masters Thesis, University of Alberta. Accessed April 10, 2021. https://era.library.ualberta.ca/files/2r36v142r.

MLA Handbook (7^th Edition):

Chen, Areana Yen. “The role of the spleen in regulation of extracellular fluid in the rat.” 1995. Web. 10 Apr 2021.

Vancouver:

Chen AY. The role of the spleen in regulation of extracellular fluid in the rat. [Internet] [Masters thesis]. University of Alberta; 1995. [cited 2021 Apr 10]. Available from: https://era.library.ualberta.ca/files/2r36v142r.

Council of Science Editors:

Chen AY. The role of the spleen in regulation of extracellular fluid in the rat. [Masters Thesis]. University of Alberta; 1995. Available from: https://era.library.ualberta.ca/files/2r36v142r

Oregon State University

10. Ford, Stephen Paul. Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries.

Degree: PhD, Animal Science, 1977, Oregon State University

URL: http://hdl.handle.net/1957/43978

► The role of estradiol- 17β, progesterone and prostaglandin F₂α (PGF₂α) in altering contractility of uterine vascular smooth muscle was investigated. A segment of uterine artery… (more)

▼ The role of estradiol- 17β, progesterone and prostaglandin F₂α (PGF₂α) in altering contractility of uterine vascular smooth muscle was investigated. A segment of uterine artery (3. 5 cm) supplying each uterine horn of ewes and heifers were removed at necropsy and perfused with oxygenated Krebs Henseleit Solution prior to initiating sequential drug perfusions. Arteries were subjected to electrical stimulation (ES) and changes in perfusion pressure due to changes in resistance to flow were recorded in mm Hg. EXPERIMENT I: Uterine arteries from unilaterally-ovulating pregnant (P) and nonpregnant (NP) ewes and heifers, necropsied on days 15 and 17 post-estrus, respectively, (estrus=day 0) were subjected to three 30 min perfusions in the order: saline, PGF₂α (1 ng/ ml) and saline. Overall, responsiveness to ES by arteries ipsilateral to ovaries bearing corpora lutea (CL) from both species was greater (P <. 01) than that of contralateral arteries in NP animals only. Arteries from NP ewes and heifers perfused with PGF₂α exhibited greater (P <. 05) smooth muscle contractility in response to ES than when arteries were perfused with saline. Perfusion of arteries from P animals with PGF₂α resulted in no change (heifers) or a decrease (P <. 05) in contractility (ewes) to ES when compared to responses of arteries to ES during saline perfusions. Perfusion of arteries from NP ewes with conceptus brei (conceptuses of day 15 P ewes) for 30 min, caused a marked decrease (P <. 01) in contractility of arteries to ES during a subsequent perfusion of PGF₂α. EXPERIMENT II: Five unilaterally-ovulating NP ewes were sacrificed on each of days 0 (estrus), 3, 6 and 10 of the estrous cycle. Regardless of stage studied, uterine arteries ipsilateral to ovaries having the greater follicular development, hereafter referred to as ipsilateral arteries, responded to ES with increased smooth muscle contractility when compared to the low consistent responses of contralateral arteries. Responses of ipsilateral arteries to ES following perfusions of saline, PGF₂α or norepinephrine (NE) increased from day 0 to 10 of the cycle. However, only ipsilateral arteries from day- 10 ewes exhibited increased (P <. 01) contractility to ES following perfusion of PGF₂α. Perfusion of phentolamine reduced contractility (P <. 01) of ips:lateral arteries to ES when compared to responses after previous perfusions of saline, PGF₂α or NE. Subsequent perfusion of PGF₂α failed to increase arterial response to ES over that exh'ibIted following phentolamine perfusion. Perfusion of ipsilateral arteries with NE after PGF₂α resulted in a return of smooth muscle contractility to ES (P <. 01). EXPERIMENT III: Sixteen ovariectomized ewes were assigned randomly to four groups and received the following treatments for one week: 1) none (controls); 2) estradiol- 17β (E₂, 54 mg implant); 3) progesterone (P4, 15 mg twice daily); and 4) E₂ + P₄. Treatment of ewes with P4 increased (P <. 01) while treatment with E ₂ decreased (P <. 01) arterial smooth muscle contraction to ES following initial… Advisors/Committee Members: Stormshak, Fredrick (advisor).

Subjects/Keywords: Uterus – Blood-vessels

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APA (6^th Edition):

Ford, S. P. (1977). Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/43978

Chicago Manual of Style (16^th Edition):

Ford, Stephen Paul. “Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries.” 1977. Doctoral Dissertation, Oregon State University. Accessed April 10, 2021. http://hdl.handle.net/1957/43978.

MLA Handbook (7^th Edition):

Ford, Stephen Paul. “Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries.” 1977. Web. 10 Apr 2021.

Vancouver:

Ford SP. Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries. [Internet] [Doctoral dissertation]. Oregon State University; 1977. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/1957/43978.

Council of Science Editors:

Ford SP. Concerted actions of ovarian steroids and prostaglandin F₂a on smooth muscle contractility of ovine and bovine uterine arteries. [Doctoral Dissertation]. Oregon State University; 1977. Available from: http://hdl.handle.net/1957/43978

Anna University

11. Sri madhava raja N. Detection and analysis of retinal vasculature using optimization based multi level thresholding;.

Degree: Detection and analysis of retinal vasculature using optimization based multi level thresholding, 2015, Anna University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/39873

►

Analysis of blood vessels in digital retinal fundus images is an important task attempted in contemporary biomedical engineering research newlineIn this work normal and abnormal… (more)

Subjects/Keywords: Analysis of blood vessels; Optimal multil

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APA (6^th Edition):

N, S. m. r. (2015). Detection and analysis of retinal vasculature using optimization based multi level thresholding;. (Thesis). Anna University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/39873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

N, Sri madhava raja. “Detection and analysis of retinal vasculature using optimization based multi level thresholding;.” 2015. Thesis, Anna University. Accessed April 10, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/39873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

N, Sri madhava raja. “Detection and analysis of retinal vasculature using optimization based multi level thresholding;.” 2015. Web. 10 Apr 2021.

Vancouver:

N Smr. Detection and analysis of retinal vasculature using optimization based multi level thresholding;. [Internet] [Thesis]. Anna University; 2015. [cited 2021 Apr 10]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/39873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

N Smr. Detection and analysis of retinal vasculature using optimization based multi level thresholding;. [Thesis]. Anna University; 2015. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/39873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Brands, J. Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart.

Degree: 2010, Maastricht University

URL: https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; 2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:isbn:9789064644108 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204

► This dissertation research studies the role of the glycocalyx, a gel layer on the inside of all blood vessels in the heart. The glycocalyx turns… (more)

Subjects/Keywords: glycocalyx; blood vessels

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APA (6^th Edition):

Brands, J. (2010). Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart. (Doctoral Dissertation). Maastricht University. Retrieved from https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; 2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:isbn:9789064644108 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204

Chicago Manual of Style (16^th Edition):

Brands, J. “Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart.” 2010. Doctoral Dissertation, Maastricht University. Accessed April 10, 2021. https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; 2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:isbn:9789064644108 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204.

MLA Handbook (7^th Edition):

Brands, J. “Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart.” 2010. Web. 10 Apr 2021.

Vancouver:

Brands J. Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart. [Internet] [Doctoral dissertation]. Maastricht University; 2010. [cited 2021 Apr 10]. Available from: https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; 2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:isbn:9789064644108 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204.

Council of Science Editors:

Brands J. Agonist-induced modulation of glycocalyx barrier properties in the microcirculation : role in blood volume recruitment and oxygen exchange in the heart. [Doctoral Dissertation]. Maastricht University; 2010. Available from: https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; 2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; urn:isbn:9789064644108 ; urn:nbn:nl:ui:27-2748fcd6-3cef-44c3-9e10-ae0df26c1204 ; https://cris.maastrichtuniversity.nl/en/publications/2748fcd6-3cef-44c3-9e10-ae0df26c1204

Columbia University

13. Avrutsky, Maria. Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion.

Degree: 2017, Columbia University

URL: https://doi.org/10.7916/D8KK9QBR

► The retina is one of the most metabolically active tissue in the body, rendering it sensitive to vascular dysfunction. Consequently, diseases that disrupt normal retinal… (more)

▼ The retina is one of the most metabolically active tissue in the body, rendering it sensitive to vascular dysfunction. Consequently, diseases that disrupt normal retinal blood supply, including retinal vein occlusions (RVO) and diabetic retinopathy, are the leading causes of blindness in working-age adults. Despite available therapies, an estimated 50% of patients do not respond to treatment. We employed a mouse model of retinal vein occlusion (RVO), achieved by tail-vein injection of rose bengal, followed by laser photocoagulation of retinal veins. In vivo analyses – optical coherence tomography (OCT), fluorescein angiography, and electroretinograms (ERGs) - were conducted with the Micron IV system (Phoenix Research Labs). RVO induces acute retinal edema, which peaks during the first 24 hours following injury. Over a 7 day time course the edema resolves, revealing a permanent retinal thinning due to death of retinal neurons. We identified caspase-9, a protease traditionally associated with apoptosis, as an essential mediator of edema. Increased levels of activated caspase-9 were detected in vascular endothelial cells 1 hour following RVO. We tested RVO in mice with inducible endothelial-cell-specific deletion of caspase-9 (iC9 ECKO). Compared to littermate controls, iC9 ECKO mice develop less edema, and sustain less retinal degeneration after RVO injury. ERG analysis showed preservation of retinal function in iC9 ECKO mice. To study whether inhibiting caspase-9 would provide protection against RVO we utilized a highly specific caspase-9 inhibitor, which we can deliver to the retina using simple eyedrops. Treatment of wildtype mice with the caspase-9 inhibitor immediately after induction of RVO provided morphologic, biochemical and functional retinal protection. Inhibition of caspase-9 reduces edema, protects retinal morphology, and helps prevent vision loss following RVO injury. Our studies indicate that endothelial caspase-9 plays an essential role in regulating edema pathogenesis. Moreover, our novel cell permeant caspase-9 inhibitor abrogates the edema and may be a potential therapy for individuals suffering from vascular eye disease.

Subjects/Keywords: Cytology; Edema; Retina – Blood-vessels; Molecular biology

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APA (6^th Edition):

Avrutsky, M. (2017). Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/D8KK9QBR

Chicago Manual of Style (16^th Edition):

Avrutsky, Maria. “Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion.” 2017. Doctoral Dissertation, Columbia University. Accessed April 10, 2021. https://doi.org/10.7916/D8KK9QBR.

MLA Handbook (7^th Edition):

Avrutsky, Maria. “Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion.” 2017. Web. 10 Apr 2021.

Vancouver:

Avrutsky M. Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion. [Internet] [Doctoral dissertation]. Columbia University; 2017. [cited 2021 Apr 10]. Available from: https://doi.org/10.7916/D8KK9QBR.

Council of Science Editors:

Avrutsky M. Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion. [Doctoral Dissertation]. Columbia University; 2017. Available from: https://doi.org/10.7916/D8KK9QBR

University of Gothenburg / Göteborgs Universitet

14. Sivertsson, Ramon, 1936-. The hemodynamic importance of structural vascular changes in essential hypertension.

Degree: 1970, University of Gothenburg / Göteborgs Universitet

URL: http://hdl.handle.net/2077/14140

Subjects/Keywords: Blood vessels; Hemodynamics

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APA (6^th Edition):

Sivertsson, Ramon, 1. (1970). The hemodynamic importance of structural vascular changes in essential hypertension. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/14140

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sivertsson, Ramon, 1936-. “The hemodynamic importance of structural vascular changes in essential hypertension.” 1970. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed April 10, 2021. http://hdl.handle.net/2077/14140.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sivertsson, Ramon, 1936-. “The hemodynamic importance of structural vascular changes in essential hypertension.” 1970. Web. 10 Apr 2021.

Vancouver:

Sivertsson, Ramon 1. The hemodynamic importance of structural vascular changes in essential hypertension. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 1970. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/2077/14140.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sivertsson, Ramon 1. The hemodynamic importance of structural vascular changes in essential hypertension. [Thesis]. University of Gothenburg / Göteborgs Universitet; 1970. Available from: http://hdl.handle.net/2077/14140

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Gothenburg / Göteborgs Universitet

15. Wendelhag, Inger, 1951-. Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia.

Degree: 1995, University of Gothenburg / Göteborgs Universitet

URL: http://hdl.handle.net/2077/14844

Subjects/Keywords: Blood vessels: ultrasonography

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APA (6^th Edition):

Wendelhag, Inger, 1. (1995). Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/14844

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wendelhag, Inger, 1951-. “Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia.” 1995. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed April 10, 2021. http://hdl.handle.net/2077/14844.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wendelhag, Inger, 1951-. “Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia.” 1995. Web. 10 Apr 2021.

Vancouver:

Wendelhag, Inger 1. Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 1995. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/2077/14844.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wendelhag, Inger 1. Ultrasound measurement of intima-media thickness and atherosclerotic plaques in carotid and femoral arteries : methodological studies and a five-year observational study in familial hypercholesterolemia. [Thesis]. University of Gothenburg / Göteborgs Universitet; 1995. Available from: http://hdl.handle.net/2077/14844

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Delft University of Technology

16. van der Velden, sander (author). Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom.

Degree: 2018, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:6da408dd-bdc9-4b1e-90c4-d9737f06af2a

► Treatment of liver diseases is often done by means of interventional radiology and thereby needles are widely used. These needles are under constant development and… (more)

Subjects/Keywords: Blood vessels; liver phantom; needle insertion forces

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APA (6^th Edition):

van der Velden, s. (. (2018). Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:6da408dd-bdc9-4b1e-90c4-d9737f06af2a

Chicago Manual of Style (16^th Edition):

van der Velden, sander (author). “Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom.” 2018. Masters Thesis, Delft University of Technology. Accessed April 10, 2021. http://resolver.tudelft.nl/uuid:6da408dd-bdc9-4b1e-90c4-d9737f06af2a.

MLA Handbook (7^th Edition):

van der Velden, sander (author). “Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom.” 2018. Web. 10 Apr 2021.

Vancouver:

van der Velden s(. Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom. [Internet] [Masters thesis]. Delft University of Technology; 2018. [cited 2021 Apr 10]. Available from: http://resolver.tudelft.nl/uuid:6da408dd-bdc9-4b1e-90c4-d9737f06af2a.

Council of Science Editors:

van der Velden s(. Needle puncture forces in liver blood vessels: Towards vein implantation in a liver phantom. [Masters Thesis]. Delft University of Technology; 2018. Available from: http://resolver.tudelft.nl/uuid:6da408dd-bdc9-4b1e-90c4-d9737f06af2a

Michigan State University

17. Halpin, Stephen T. Modeling the vascular system with microfluidic technology.

Degree: 2012, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:1636

►

Thesis Ph. D. Michigan State University, Chemistry 2012.

Here are presented several technologies advancing the state of microfluidic modeling of the vascular system through the… (more)

▼

Thesis Ph. D. Michigan State University, Chemistry 2012.

Here are presented several technologies advancing the state of microfluidic modeling of the vascular system through the integration of high throughput analysis equipment with microfluidic systems, allowing for the monitoring of cell-cell communication between the red blood cell (RBC) and endothelial cells. A review of the prior knowledge of the role of adenosine triphosphate (ATP) and nitric oxide (NO) release from the RBC is presented, along with the current understanding of the role these molecules play in vasodilation along with the endothelium. Here, this dissertation hypothesizes that hypoxic vasodilation of blood vessels requires ATP release from the RBC that stimulates NO synthesis in the endothelium, resulting in vasodilation. To investigate this hypothesis, a microfluidic model capable of quantitatively determining NO and culturing endothelial cells near a flowing RBC channel is fabricated. Techniques for fabrication of microfluidic devices are reviewed, along with detection and cell culture systems integrated in microfluidic systems. First presented is a novel system for analysis of NO released from RBCs under hypoxic conditions that uses a polydimethylsiloxane (PDMS) based microfluidic device incorporating a polycarbonate membrane. This membrane separates a flowing RBC sample from fluorogenic probe, DAF-FM, which when reacted with NO, has a larger fluorescence emission. This device was designed to be integrated into a fluorescence plate reader to obtain readout, which was a significant improvement over prior systems requiring custom detection platforms or microscopes for readout. Using this technology, a significant increase in NO release from RBCs under hypoxic conditions was observed.Next endothelial cell culture was incorporated onto the membrane of the device, and inhibition studies performed to investigate the origin of NO which reaches beyond an endothelial layer. In this model system, NO measured above an endothelial layer is representative of that available to the smooth muscle to induce vasodilation. Using this system, which integrated novel approaches of using the DAF-FM probe for NO in an extracellular manner and plate reader detection, it was shown that under hypoxic conditions, an increase in NO detected above the endothelium only is observed when RBC ATP release function and endothelial NO synthesis function is present, suggesting a pathway of hypoxic vasodilation requiring RBC ATP release and endothelial NO productionAlso, technology was developed enabling electrochemical oxygen detection within a flowing channel on a microfluidic device using epoxy-immobilized gold and silver wires as working and reference electrodes, respectively. This presents an easily reusable and low cost platform to potentially vary then detect the oxygen concentration in a flowing cell sample prior to other analysis. This would allow the investigation of hypoxic systems at oxygen concentrations other than completely oxygenated, or completely deoxygenated.…

Advisors/Committee Members: Spence, Dana M, Swain, Greg M, Jones, A Daniel, Walker, Kevin D.

Subjects/Keywords: Blood-vessels; Microfluidics; Fluid dynamics; Chemistry

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APA (6^th Edition):

Halpin, S. T. (2012). Modeling the vascular system with microfluidic technology. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:1636

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Halpin, Stephen T. “Modeling the vascular system with microfluidic technology.” 2012. Thesis, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:1636.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Halpin, Stephen T. “Modeling the vascular system with microfluidic technology.” 2012. Web. 10 Apr 2021.

Vancouver:

Halpin ST. Modeling the vascular system with microfluidic technology. [Internet] [Thesis]. Michigan State University; 2012. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:1636.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Halpin ST. Modeling the vascular system with microfluidic technology. [Thesis]. Michigan State University; 2012. Available from: http://etd.lib.msu.edu/islandora/object/etd:1636

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

18. 趙瑩子. Acute and chronic impact of pressure on vascular responsiveness.

Degree: 2014, University of Hong Kong

URL: http://hdl.handle.net/10722/207185

► Hypertension leads to vascular complications including endothelial dysfunction, heart failure and stroke. The purpose of the present studies was to investigate the chronic and acute… (more)

▼ Hypertension leads to vascular complications including endothelial dysfunction, heart failure and stroke. The purpose of the present studies was to investigate the chronic and acute impact of high pressure on vascular responsiveness. In Study I, isometric tension measurements demonstrated that contractions to phenylephrine, in the presence of indomethacin (inhibitor of cyclooxygenase), were smaller in aortae of spontaneously hypertensive rats (SHR) with, than in those without, endothelium, while they were comparable in such preparations of normotensive Wistar-Kyoto rat (WKY); the difference in SHR aortae was not affected by L-NAME [inhibitor of nitric oxide synthase (NOS)]. This endothelium-dependent, NOS-independent inhibition of phenylephrine-induced contraction was greater in older SHR (36 versus 18 weeks), and abolished by NO scavengers and ODQ (inhibitor of soluble guanylyl cyclase). It was observed not only in the presence of indomethacin but also apocynin (antioxidant), but inhibited by diphenyleneiodonium (inhibitor of cytochrome P450 reductase). These results suggest that the endothelium-dependent, eNOS-independent inhibition is caused by NO produced by cytochrome P450 reductase in the endothelium of the SHR aorta. Study II investigated the mechanisms underlying the reduced contractions to prostaglandin E2 [agonist of prostaglandin E2 and thromboxane-prostanoid (TP) receptors] by a previous exposure to phenylephrine (agonist of α1-adrenoceptor) in the aortic smooth muscle of the SHR. This inhibition induced by the pre-activation of α1-adrenoceptor was augmented in aortae of older SHR (36 versus 18 weeks) and was not present in WKY preparations. Pre-exposure to the protein kinase C (PKC) activator, phorbol 12,13-dibutyrate, also inhibited subsequent contractions to prostaglandin E2 in SHR aortae. Inhibition of PKC by calphostin C abolished the effect of pre-exposure to phenylephrine. The mRNA expressions of PKC isoforms differed in WKY and SHR smooth muscle. These experiments suggest that in the SHR but not the WKY aorta, α1-adrenergic activation causes heterologous desensitization of TP receptor through activation of a specific PKC isoform(s). In Study III, experiments were performed in a pressure myograph to determine whether or not acute elevation of transmural pressure in the isolated carotid artery of adult mouse (10-12 weeks) impairs endothelium-dependent dilatation by increasing angiotensin II expression or by directly activating AT1 receptors. Transient exposure of arteries to increased pressure (150 mmHg, three hours) inhibited endothelium-dependent, NO-mediated dilatations to acetylcholine, but did not affect responses to the NO donor DETA-NONOate. Inhibiting angiotensin II signaling or angiotensin converting enzyme prevented the impairment of endothelium-dependent dilatation by elevated pressure. Elevated pressure increased the expression of angiotensinogen [precursor of angiotensin II]. Thus, exposure of carotid arteries to elevated pressure leads to local release of angiotensin II,… Advisors/Committee Members: Leung, SWS (advisor), Vanhoutte, PMGR (advisor), Xu, A (advisor).

Subjects/Keywords: Blood-vessels; Hypertension

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APA (6^th Edition):

趙瑩子. (2014). Acute and chronic impact of pressure on vascular responsiveness. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/207185

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

趙瑩子. “Acute and chronic impact of pressure on vascular responsiveness.” 2014. Thesis, University of Hong Kong. Accessed April 10, 2021. http://hdl.handle.net/10722/207185.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

趙瑩子. “Acute and chronic impact of pressure on vascular responsiveness.” 2014. Web. 10 Apr 2021.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete

Vancouver:

趙瑩子. Acute and chronic impact of pressure on vascular responsiveness. [Internet] [Thesis]. University of Hong Kong; 2014. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10722/207185.

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

趙瑩子. Acute and chronic impact of pressure on vascular responsiveness. [Thesis]. University of Hong Kong; 2014. Available from: http://hdl.handle.net/10722/207185

Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

19. Keung, Wen-yee, Wendy. Mechanisms of acute actions of 17B-estradiol in the vascular system.

Degree: 2001, University of Hong Kong

URL: http://hdl.handle.net/10722/30753

Subjects/Keywords: Blood-vessels.; Estradiol.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Keung, W. (2001). Mechanisms of acute actions of 17B-estradiol in the vascular system. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/30753

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Keung, Wen-yee,. “Mechanisms of acute actions of 17B-estradiol in the vascular system.” 2001. Thesis, University of Hong Kong. Accessed April 10, 2021. http://hdl.handle.net/10722/30753.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Keung, Wen-yee,. “Mechanisms of acute actions of 17B-estradiol in the vascular system.” 2001. Web. 10 Apr 2021.

Vancouver:

Keung W. Mechanisms of acute actions of 17B-estradiol in the vascular system. [Internet] [Thesis]. University of Hong Kong; 2001. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10722/30753.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Keung W. Mechanisms of acute actions of 17B-estradiol in the vascular system. [Thesis]. University of Hong Kong; 2001. Available from: http://hdl.handle.net/10722/30753

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Pearson, Thomas Michael Charles. Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease.

Degree: PhD, 2019, University of Edinburgh

URL: http://hdl.handle.net/1842/36150

► Purpose Investigate changes in retinal structure and function caused by multiple sclerosis (MS) using established and novel modes of image acquisition and analysis, in order… (more)

▼ Purpose Investigate changes in retinal structure and function caused by multiple sclerosis (MS) using established and novel modes of image acquisition and analysis, in order to identify candidate biomarkers of disease. Use longitudinal analysis to determine the rate at which changes to the retinal anatomy occur and whether this rate-of-change alters throughout the MS disease course. Method Within the Anne Rowling Regenerative Neurology Clinic (Royal Infirmary of Edinburgh), 72 MS participants (53 female, 19 male, age range 20-79, median age 44) and 80 healthy volunteers (HV) (61 female, 19 male, age range 23-73, median age 38) received spectral domain optical coherence tomography (SD-OCT) and ultra-wide field scanning laser ophthalmoscope (UWF-SLO) scans at baseline. Within the MS group, 16 (9 right eyes and 10 left eyes) had at least one clinically diagnosed episode of optic neuritis (ON). Follow up scans were taken at approximately 3, 6 and 12-month intervals over the course of two years. Visual acuity (VA) as an indicator of retinal function was also measured at each visit using Sloan letter charts at 100% and 2.5% illumination. Through proprietary software, automatic segmentation of SD-OCT images quantified changes to retinal nerve fibre layer (RNFL) thickness and macular volume. Novel image processing algorithms specifically adapted to semi-automatically segment the vasculature in UWF-SLO images (using multi-scale filtering and supervised classification) allowed for measurement of vessel diameter. Data from the 3 participant groups (MS (no ON), MS (ON) and HV) was first tested statistically for significant differences. Linear regression modelling with the inclusion of disease, sex, length-of-disease and age as predictors was then used to estimate the true effects of disease on the retinal anatomy without confounders. Results Baseline data showed that individuals with MS (no ON) have a reduced RNFL thickness in all peripapillary regions and a reduced macular volume when compared with HVs. The reduction in RNFL thickness was seen globally in both eyes (OS: -10μm, OD: -11μm, p<0.001) but was greatest in the inferior temporal region (OS: -15μm, OD: -13μm, p<0.01). In the MS (ON) group the reduction in RNFL thickness was even greater, again being largest in the inferior temporal region (OS: -29μm, OD: -24μm). Linear regression models confirmed the effect of disease on RNFL thickness and macular volume with significant coefficients in all regions but the inferior nasal. Follow-up analysis showed that the MS (no ON) group had a larger annual rate-of-thinning of the RNFL than HVs in the majority of regions, the largest difference being in the inferior nasal (OS: -1.32μm/year, OD: -1.06μm/year, p<0.05) and superior nasal (OS: - 1.11μm/year, OD: -1.13μm/year, p<0.05) regions. Retinal arteries were shown to have a significantly reduced diameter in only the inferior nasal quadrant, where the greatest reduction in vessel width was found (OS: -0.005mm, OD: - 0.007mm, p<0.05). For mean venous width, the inferior nasal quadrant…

Subjects/Keywords: multiple sclerosis; retinal scanning; retinal blood vessels

11 more images…

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APA (6^th Edition):

Pearson, T. M. C. (2019). Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/36150

Chicago Manual of Style (16^th Edition):

Pearson, Thomas Michael Charles. “Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease.” 2019. Doctoral Dissertation, University of Edinburgh. Accessed April 10, 2021. http://hdl.handle.net/1842/36150.

MLA Handbook (7^th Edition):

Pearson, Thomas Michael Charles. “Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease.” 2019. Web. 10 Apr 2021.

Vancouver:

Pearson TMC. Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease. [Internet] [Doctoral dissertation]. University of Edinburgh; 2019. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/1842/36150.

Council of Science Editors:

Pearson TMC. Multi-modal retinal scanning for diagnostic and therapeutic biomarker discovery in neurodegenerative disease. [Doctoral Dissertation]. University of Edinburgh; 2019. Available from: http://hdl.handle.net/1842/36150

Macquarie University

21. Raoufi-Rad, Newsha. Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models.

Degree: 2016, Macquarie University

URL: http://hdl.handle.net/1959.14/1121699

►

Theoretical thesis.

Bibliography: pages 162-194.

Chapter 1. Introduction – Chapter 2. General methods – Chapter 3. Quantitative analysis of gene and protein expression of endothelial… (more)

▼

Theoretical thesis.

Bibliography: pages 162-194.

Chapter 1. Introduction – Chapter 2. General methods – Chapter 3. Quantitative analysis of gene and protein expression of endothelial cell adhesion molecules after radiation – Chapter 4.Anatomical localisation and quantification of post-radiosurgery ICAM-1 and VCAM-1 expression in an AVM animal model – Chapter 5. Phosphatidylserine translocation and anatomical location post-irradiation in an AVM animal model – Chapter 6. Summary and conclusions.

Brain arteriovenous malformations are a leading cause of stroke in children and young adults. They account for 4% of haemorrhagic strokes. Arteriovenous malformations (AVMs) are complex vascular lesions, characterised by abnormal connections between arteries and veins that lack a capillary network. The treatment options for AVMs include surgery, radiosurgery and embolisation. However, over one third of AVM patients with large and deep AVMs cannot be safely and effectively treated with current methods. Therefore, a new treatment method is required for these patients with life-threatening AVMs. A biological technique that can be harnessed to enhance the rate of occlusion or thrombosis inside the AVM blood vessels is highly attractive. A proposed method to achieve this goal is vascular targeting. This approach has been applied in cancer therapy where unique molecular markers expressed on the surface of tumour vessels are targeted by conjugated antibodies and pro-thrombotic factors to induce thrombosis inside the tumour vessels. If such a technique can be used for AVM treatment, it will open a new window toward treatment of life-threatening AVMs. In order to follow this path, specific markers on the surface of the AVM endothelium need to be identified for selective targeting. However, previous studies have shown that AVM endothelial cells are not dramatically different to normal endothelial cells. Therefore, a priming mechanism is required. It is hypothesised that radiosurgery induces molecular changes on the surface of endothelial cells that can be used to discriminate irradiated vessels from normal vessels. Previous studies have shown radiation can induce endothelial membrane changes, such as phosphatidylserine (PS) translocation and up-regulation of various cell adhesion molecules (CAMs), including intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), P-selectin and E-selectin, both in vitro and in vivo. Therefore, the aims of this study were as follows: 1) to examine which of the CAMs elicits the greatest response to radiation in endothelial cells in vitro and may provide the best candidate for a vascular targeting approach; 2) to determine the lowest radiation dose (5, 15 or 25 Gy) able to elicit a significant response in these molecules in vitro, as lower doses reduce the risk of off-target radiation damage to normal cells; 3) to determine the most discriminating CAMs in an AVM animal model; and 4) to examine the in vivo externalisation of PS in response to radiosurgery in…

Advisors/Committee Members: Macquarie University. Department of Clinical Medicine.

Subjects/Keywords: Cerebral arteriovenous malformations – Treatment; Blood vessels – Surgery

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APA (6^th Edition):

Raoufi-Rad, N. (2016). Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models. (Doctoral Dissertation). Macquarie University. Retrieved from http://hdl.handle.net/1959.14/1121699

Chicago Manual of Style (16^th Edition):

Raoufi-Rad, Newsha. “Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models.” 2016. Doctoral Dissertation, Macquarie University. Accessed April 10, 2021. http://hdl.handle.net/1959.14/1121699.

MLA Handbook (7^th Edition):

Raoufi-Rad, Newsha. “Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models.” 2016. Web. 10 Apr 2021.

Vancouver:

Raoufi-Rad N. Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models. [Internet] [Doctoral dissertation]. Macquarie University; 2016. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/1959.14/1121699.

Council of Science Editors:

Raoufi-Rad N. Developing new treatments for brain arteriovenous malformations: molecular responses to radiation in in vitro and in vivo models. [Doctoral Dissertation]. Macquarie University; 2016. Available from: http://hdl.handle.net/1959.14/1121699

Michigan State University

22. Jenkins, Thomas William. The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey).

Degree: MS, 1950, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:14527

Subjects/Keywords: Squirrels; Blood-vessels

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APA (6^th Edition):

Jenkins, T. W. (1950). The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey). (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:14527

Chicago Manual of Style (16^th Edition):

Jenkins, Thomas William. “The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey).” 1950. Masters Thesis, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:14527.

MLA Handbook (7^th Edition):

Jenkins, Thomas William. “The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey).” 1950. Web. 10 Apr 2021.

Vancouver:

Jenkins TW. The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey). [Internet] [Masters thesis]. Michigan State University; 1950. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:14527.

Council of Science Editors:

Jenkins TW. The anatomy of the blood vascular system of the fox squirrel, Sciurus niger rufiventer (Geoffrey). [Masters Thesis]. Michigan State University; 1950. Available from: http://etd.lib.msu.edu/islandora/object/etd:14527

Michigan State University

23. Wells, Charles Henry. Estimation of renal venous resistance and its significance to autoregulation in the dog kidney.

Degree: MS, 1960, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:13816

Subjects/Keywords: Kidneys – Blood-vessels

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APA (6^th Edition):

Wells, C. H. (1960). Estimation of renal venous resistance and its significance to autoregulation in the dog kidney. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:13816

Chicago Manual of Style (16^th Edition):

Wells, Charles Henry. “Estimation of renal venous resistance and its significance to autoregulation in the dog kidney.” 1960. Masters Thesis, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:13816.

MLA Handbook (7^th Edition):

Wells, Charles Henry. “Estimation of renal venous resistance and its significance to autoregulation in the dog kidney.” 1960. Web. 10 Apr 2021.

Vancouver:

Wells CH. Estimation of renal venous resistance and its significance to autoregulation in the dog kidney. [Internet] [Masters thesis]. Michigan State University; 1960. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:13816.

Council of Science Editors:

Wells CH. Estimation of renal venous resistance and its significance to autoregulation in the dog kidney. [Masters Thesis]. Michigan State University; 1960. Available from: http://etd.lib.msu.edu/islandora/object/etd:13816

Michigan State University

24. Ploucha, James Mattes. Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken.

Degree: PhD, Department of Physiology (and) Department of Animal Science, 1982, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:37222

Subjects/Keywords: Blood-vessels; Chickens

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APA (6^th Edition):

Ploucha, J. M. (1982). Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:37222

Chicago Manual of Style (16^th Edition):

Ploucha, James Mattes. “Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken.” 1982. Doctoral Dissertation, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:37222.

MLA Handbook (7^th Edition):

Ploucha, James Mattes. “Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken.” 1982. Web. 10 Apr 2021.

Vancouver:

Ploucha JM. Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken. [Internet] [Doctoral dissertation]. Michigan State University; 1982. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:37222.

Council of Science Editors:

Ploucha JM. Effect of hemorrhage, vasoactive agents, asphyxia and exercise on the vasculature of the chicken. [Doctoral Dissertation]. Michigan State University; 1982. Available from: http://etd.lib.msu.edu/islandora/object/etd:37222

Delft University of Technology

25. Visser, Dmitri (author). Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation.

Degree: 2018, Delft University of Technology

URL: http://resolver.tudelft.nl/uuid:719c107b-67a2-497d-991a-a70b0cb992aa

►

With the recent developments in tissue-engineered organ substitutes, there has been an increasing demand for novel culturing techniques to create biological substitutes in vitro, as… (more)

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With the recent developments in tissue-engineered organ substitutes, there has been an increasing demand for novel culturing techniques to create biological substitutes in vitro, as well as reliable and efficient test methods that can assess their biocompatibility and mechanical performance. In the past two decades, perfusion bioreactors have proved to be important tools in the creation, control, and evaluation of cell cultures and engineered tissues under precisely controlled in vitro conditions that simulate the physiological environment. Due to the demanding requirements for blood vessel substitutes, they have been extensively deployed in the culture and conditioning experiments of novel tissue-engineered vascular grafts (TEVGs) and have been often used to study haemodynamic mechanic stimuli, including the cyclic vessel expansion and wall shear stress. However, a key limitation of the currently available TEVG perfusion bioreactors is their often complex design and operation and the lack of standardisation of the mechanical characterisation. In this study, the goal was to design, characterise, and construct a TEVG perfusion bioreactor that is foremost simpler to operate and extends the capabilities of particular currently available set-ups. A modular bioreactor design is presented that allows for the toolless mounting of the graft with a diameter up to 6 mm and features completely separated circuits for the intra- and extraluminal side of the scaffold wall. The culture chamber encloses a removable graft frame, mainly machined out of polyether ether ketone (PEEK). In silico simulations have been used to assess local fluid dynamics within the scaffold, to predict the reliability of the simulated culture conditions. The presented design allows the exertion of a broad range of physiologically relevant shear stresses on cultured TEVGs, including arterial shear stresses. A test for the in vitro cytotoxicity showed that the medium extracts of the constructed graft frame did not show any cytotoxic potential. Finally, an assessment method for the estimation of the radial compliance is proposed, which aims to adhere to the relevant international standards on the mechanical characterisation of vascular substitutes.

Biomedical Engineering

Advisors/Committee Members: Hinderer, Svenja (mentor), Fratila-Apachitei, Lidy (mentor), Zadpoor, Amir (graduation committee), Kenjeres, Sasa (graduation committee), Delft University of Technology (degree granting institution).

Subjects/Keywords: bioreactor; cardiovascular disease; tissue engineering; Blood vessels

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APA (6^th Edition):

Visser, D. (. (2018). Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation. (Masters Thesis). Delft University of Technology. Retrieved from http://resolver.tudelft.nl/uuid:719c107b-67a2-497d-991a-a70b0cb992aa

Chicago Manual of Style (16^th Edition):

Visser, Dmitri (author). “Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation.” 2018. Masters Thesis, Delft University of Technology. Accessed April 10, 2021. http://resolver.tudelft.nl/uuid:719c107b-67a2-497d-991a-a70b0cb992aa.

MLA Handbook (7^th Edition):

Visser, Dmitri (author). “Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation.” 2018. Web. 10 Apr 2021.

Vancouver:

Visser D(. Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation. [Internet] [Masters thesis]. Delft University of Technology; 2018. [cited 2021 Apr 10]. Available from: http://resolver.tudelft.nl/uuid:719c107b-67a2-497d-991a-a70b0cb992aa.

Council of Science Editors:

Visser D(. Creating a simplified and standardised bioreactor system for tissue-engineered vascular graft culturing and characterisation. [Masters Thesis]. Delft University of Technology; 2018. Available from: http://resolver.tudelft.nl/uuid:719c107b-67a2-497d-991a-a70b0cb992aa

Stellenbosch University

26. Van der Merwe, Tys. Development of a guidance and Intra-Arterial flow monitoring catheter.

Degree: MEng, Mechanical and Mechatronic Engineering, 2016, Stellenbosch University

URL: http://hdl.handle.net/10019.1/100258

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ENGLISH ABSTRACT: This thesis entails the development and testing of devices that can aid in guiding a needle into a blood vessel. Furthermore, a concept… (more)

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ENGLISH ABSTRACT: This thesis entails the development and testing of devices that can aid in guiding a needle into a blood vessel. Furthermore, a concept flow meter is also developed and tested. Physicians often have difficulty placing a needle in blood vessels. For a number of procedures access to blood vessels are required. Investigating methods to ease this process is thus beneficial to the medical field. Likewise, measuring blood flow is also of importance in the medical field. Measuring blood flow to the brain can prevent brain ischemia, which can lead to death of brain tissue. Near infrared (NIR) light is used to guide the needle towards a blood vessel. Two optic fibre strands are placed inside the needle, one to transmit NIR light and one to receive reflected light. The reflected light, when pointing at blood, is different from other tissue types. The in vitro and in vivo tests both showed that there is a statistically significant difference (p < 0.001) in reflected light when pointing at and away from a blood vessel. Electrical impedance is used to determine when the needle enters a blood vessel. A sine wave is generated and passed through biological tissue. The measured impedance is different for blood and other tissue types. It was found that when a signal of 29.85 kHz was used, there was a statistically significant difference (p < 0.001) between blood and muscle and blood and fat. The flow meter works on the principle of thermal convection. The concept device that is developed, has an ambient temperature sensor and a second temperature sensor wrapped in a heating coil. In the presence of fluid flow, heat is carried away from the heater by thermal convection, causing a temperature drop. The device was tested in vitro in distilled water flow and blood flow at flow rates between 0.1 ml/s and 0.45 ml/s. Both the fluids had high variances in the temperature difference between the ambient and heater temperature. By removing the offsets, clear trends become visible. For the distilled water tests, a fit in the tested flow region was obtained with a coefficient of determination of R2 = 0:9801. The blood tests however were more erratic and the best fit that could be obtained had a coefficient of determination of R2 = 0:6056. In both cases however, CFD results indicate that this method is a viable method if some of the flow meter design aspects are improved. The results indicate that a combination of the aforementioned technologies can be used to guide a needle into a blood vessel and measure flow rate. While further investigation is required to make this a product in the medical practice, the investigation in this thesis serves as a basis for future clinical trials in the development of a guidance and intra-arterial flow monitoring catheter.

AFRIKAANSE OPSOMMING: Die tesis behels die ontwikkeling en toets van toestelle wat ’n naald kan lei tot in ’n bloedvat. Verder is ’n konsep vloeimeter ook ontwikkel en getoets. Dokters beskou dit gereeld as ’n uitdaging om ’n naald in ’n…

Advisors/Committee Members: Van der Merwe, Johan, Fourie, Pieter R., Stellenbosch University. Faculty of Engineering. Dept. of Mechanical and Mechatronic Engineering..

Subjects/Keywords: Intra-arterial injections; Blood-vessels – Anatomy; Circulatory system; Blood-vessels – Endoscopic surgery; UCTD

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APA (6^th Edition):

Van der Merwe, T. (2016). Development of a guidance and Intra-Arterial flow monitoring catheter. (Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/100258

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Van der Merwe, Tys. “Development of a guidance and Intra-Arterial flow monitoring catheter.” 2016. Thesis, Stellenbosch University. Accessed April 10, 2021. http://hdl.handle.net/10019.1/100258.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Van der Merwe, Tys. “Development of a guidance and Intra-Arterial flow monitoring catheter.” 2016. Web. 10 Apr 2021.

Vancouver:

Van der Merwe T. Development of a guidance and Intra-Arterial flow monitoring catheter. [Internet] [Thesis]. Stellenbosch University; 2016. [cited 2021 Apr 10]. Available from: http://hdl.handle.net/10019.1/100258.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Van der Merwe T. Development of a guidance and Intra-Arterial flow monitoring catheter. [Thesis]. Stellenbosch University; 2016. Available from: http://hdl.handle.net/10019.1/100258

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ryerson University

27. Lee, Benjamin. Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound.

Degree: 2011, Ryerson University

URL: https://digital.library.ryerson.ca/islandora/object/RULA%3A1485

► 2D Doppler ultrasound can be used for continuous monitoring of vasospasm. However, the use of Doppler ultrasound suffers from operator dependence requiring a skilled ultrasonographer… (more)

Subjects/Keywords: Doppler ultrasonography; Blood-vessels – Imaging; Blood flow – Imaging

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APA (6^th Edition):

Lee, B. (2011). Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound. (Thesis). Ryerson University. Retrieved from https://digital.library.ryerson.ca/islandora/object/RULA%3A1485

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lee, Benjamin. “Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound.” 2011. Thesis, Ryerson University. Accessed April 10, 2021. https://digital.library.ryerson.ca/islandora/object/RULA%3A1485.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lee, Benjamin. “Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound.” 2011. Web. 10 Apr 2021.

Vancouver:

Lee B. Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound. [Internet] [Thesis]. Ryerson University; 2011. [cited 2021 Apr 10]. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1485.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lee B. Signal processing techniques for operator independent Doppler ultrasound : potential for use in transcranial Doppler ultrasound. [Thesis]. Ryerson University; 2011. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A1485

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vilnius Gediminas Technical University

28. Kuzborska, Zyta. Research of blood flow and stresses in the pathological blood vessels.

Degree: PhD, Mechanical Engineering, 2012, Vilnius Gediminas Technical University

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904 ;

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Physical load, age and gender influence to blood pressure and maximal stresses in the pathological blood vessel palaces was studies in this work. The main… (more)

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Physical load, age and gender influence to blood pressure and maximal stresses in the pathological blood vessel palaces was studies in this work. The main research subject – pathological blood vessel and its blood flow processes that depend on physical load, pathology degree and type, age, gender and blood vessels stress characteristics. The main aim of this work – to examine blood flow characteristics, local blood pressure, stress distribution in the pathological blood vessels dependent physical load assessing blood vessels mechanical properties variations due to age, gender, blood vessel pathology type; to make simplified human efficiency evaluation methodology. The paper analyse a few main tasks: to explore physical load, blood vessels pathology degree, age and gender influence to blood pressure and tensions increase in the pathological blood vessels locations; experimentally determine blood flow rates changes in pathological blood vessels assessing; additionally investigate blood pressure and heart rate characteristics variations during set physical load and human working age range. This paper consists of introduction, four chapters, summary, literature and authors publications theses lists and two annexes. Introductory chapter discusses the test problem, work topicality, research subject, also formulates work subject and tasks, and describes research methodology, work scientific novelty, practical value of the work results, defended propositions. In the introduction end... [to full text]

Disertacijoje nagrinėjama fizinio krūvio, amžiaus bei lyties įtaka kraujo spaudimui ir didžiausiems įtempiams pažeistoje kraujagyslės vietoje. Pagrindinis tyrimo objektas – ligos pažeista kraujagyslė ir joje vykstantys kraujo tėkmės procesai, priklausantys nuo fizinio krūvio dydžio, pažeidimo laipsnio ir rūšies, amžiaus, lyties, bei šių veiksnių įtaka didžiausiems įtempiams ir spaudimui pažeistose vietose. Pagrindinis disertacijos tikslas – ištirti kraujo tėkmės charakteristikas, lokalinį kraujo spaudimą, įtempių pasiskirstymą pažeistose kraujagyslėse priklausomai nuo fizinio krūvio, įvertinant kraujagyslių mechaninių savybių pokytį dėl amžiaus, lyties, kraujagyslės pažeidimo rūšies, ir sudaryti supaprastintą darbingumo verti-nimo metodiką. Darbe sprendžiami keli uždaviniai: ištirti fizinės apkrovos dydžio, kraujagyslių pažeidimų laipsnio, amžiaus ir lyties įtaką kraujo spaudimui ir įtempių padidėjimui pažeistose kraujagyslių vietose; ekspe-rimentiniu būdu nustatyti kraujo tėkmės rodiklių pokyčius pažeistose kraujagyslėse; ištirti kraujo spaudimo ir širdies susitraukimų dažnio charakteristikų pokyčius nustatytame fizinio krūvio ir žmogaus darbingo amžiaus intervale. Disertaciją sudaro įvadas, keturi skyriai, rezultatų apibendrinimas, naudotos literatūros ir autorės publikacijų disertacijos tema sąrašai ir du priedai. Įvadiniame skyriuje aptariama tiriamoji problema, darbo aktualumas, aprašomas tyrimų objektas, formuluojamas darbo tikslas bei uždaviniai, aprašoma tyrimų... [toliau žr. visą tekstą]

Advisors/Committee Members: Mariūnas, Mečislovas (Doctoral dissertation supervisor), Kačianauskas, Rimantas (Doctoral dissertation committee chair), Alekna, Vitmantas (Doctoral dissertation committee member), Atkočiūnas, Juozas (Doctoral dissertation committee member), Toločka, Rymantas Tadas (Doctoral dissertation committee member), Vekteris, Vladas (Doctoral dissertation committee member), Juocevičius, Alvydas (Doctoral dissertation opponent), Leonavičius, Mindaugas Kazimieras (Doctoral dissertation opponent).

Subjects/Keywords: Blood vessels; Blood flow; Pathological; Kraujogyslė; Kraujo tėkmė; Patologija

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kuzborska, Z. (2012). Research of blood flow and stresses in the pathological blood vessels. (Doctoral Dissertation). Vilnius Gediminas Technical University. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904 ;

Chicago Manual of Style (16^th Edition):

Kuzborska, Zyta. “Research of blood flow and stresses in the pathological blood vessels.” 2012. Doctoral Dissertation, Vilnius Gediminas Technical University. Accessed April 10, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904 ;.

MLA Handbook (7^th Edition):

Kuzborska, Zyta. “Research of blood flow and stresses in the pathological blood vessels.” 2012. Web. 10 Apr 2021.

Vancouver:

Kuzborska Z. Research of blood flow and stresses in the pathological blood vessels. [Internet] [Doctoral dissertation]. Vilnius Gediminas Technical University; 2012. [cited 2021 Apr 10]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904 ;.

Council of Science Editors:

Kuzborska Z. Research of blood flow and stresses in the pathological blood vessels. [Doctoral Dissertation]. Vilnius Gediminas Technical University; 2012. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120131_135725-24904 ;

Michigan State University

29. Lyon, Carol Ann Kindermann. Flow through collapsible vessels.

Degree: MS, 1978, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:35273

Subjects/Keywords: Blood-vessels; Blood flow; Hemodynamics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lyon, C. A. K. (1978). Flow through collapsible vessels. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:35273

Chicago Manual of Style (16^th Edition):

Lyon, Carol Ann Kindermann. “Flow through collapsible vessels.” 1978. Masters Thesis, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:35273.

MLA Handbook (7^th Edition):

Lyon, Carol Ann Kindermann. “Flow through collapsible vessels.” 1978. Web. 10 Apr 2021.

Vancouver:

Lyon CAK. Flow through collapsible vessels. [Internet] [Masters thesis]. Michigan State University; 1978. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:35273.

Council of Science Editors:

Lyon CAK. Flow through collapsible vessels. [Masters Thesis]. Michigan State University; 1978. Available from: http://etd.lib.msu.edu/islandora/object/etd:35273

Michigan State University

30. Replogle, Clyde Rayburn. A proposed model for renal blood flow control.

Degree: PhD, Department of Physiology, 1967, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:35065

Subjects/Keywords: Kidneys – Blood-vessels; Blood – Circulation

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Replogle, C. R. (1967). A proposed model for renal blood flow control. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:35065

Chicago Manual of Style (16^th Edition):

Replogle, Clyde Rayburn. “A proposed model for renal blood flow control.” 1967. Doctoral Dissertation, Michigan State University. Accessed April 10, 2021. http://etd.lib.msu.edu/islandora/object/etd:35065.

MLA Handbook (7^th Edition):

Replogle, Clyde Rayburn. “A proposed model for renal blood flow control.” 1967. Web. 10 Apr 2021.

Vancouver:

Replogle CR. A proposed model for renal blood flow control. [Internet] [Doctoral dissertation]. Michigan State University; 1967. [cited 2021 Apr 10]. Available from: http://etd.lib.msu.edu/islandora/object/etd:35065.

Council of Science Editors:

Replogle CR. A proposed model for renal blood flow control. [Doctoral Dissertation]. Michigan State University; 1967. Available from: http://etd.lib.msu.edu/islandora/object/etd:35065

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