subject:(Blood flow)

University of Illinois – Chicago

1. Hsu, Chih-Yang. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.

Degree: 2017, University of Illinois – Chicago

► There is a fundamental gap in how blood flow quantification can be accomplished in interventional digital subtraction angiography (DSA) to provide physicians with measurements to… (more)

▼ There is a fundamental gap in how blood flow quantification can be accomplished in interventional digital subtraction angiography (DSA) to provide physicians with measurements to interpret the patient’s vascular health. Continued existence of this gap represents an important problem because, until it is filled, physicians can only rely on qualitative information of intensity changes to understand blood flow variations caused by the intervention treatment. The long-term goal is to transform DSA, the gold standard for qualitative blood flow assessment, into a fully automated quantitative measurement tool that can potentially aid clinical decision making in endovascular interventions. Current approaches focus on using signals from a single vessel to determine blood flow and have not been successful due to the slow frame rate. It is our central hypothesis that a radically different flow quantification approach, using all the information from the entire image set concurrently to overcome the slow DSA frame rate, will provide reliable blood flow measurement in all vessels. The immediate objective is to create the proposed whole-tree DSA blood flow measurement method and to test its feasibility and accuracy. Success here would justify a future clinical trial of DSA-based flow measurement. The results of our study will be used to determine whether our global approach can provide reliable flow quantification in a clinical situation. The approach is innovative, because it uses global information to reliably measurement the blood flow rate in DSA. The proposed research is significant, because it is expected to rapidly produce reliable flow measurements in all visible vessels to facilitate physician’s understanding of patient’s vascular status. The novel technique will gap the bridge between the large arteries and micro vessels, providing flow measurements in all visible vessels that can be used to study cerebral hemodynamics. Ultimately, such technique has the potential to alternate clinical decision making for better treatment prognosis to reduce healthcare cost in treating cerebral vascular diseases. Advisors/Committee Members: Linninger, Andreas (advisor).

Subjects/Keywords: Blood vessels; blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hsu, C. (2017). Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/21822

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hsu, Chih-Yang. “Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.” 2017. Thesis, University of Illinois – Chicago. Accessed December 14, 2019. http://hdl.handle.net/10027/21822.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hsu, Chih-Yang. “Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture.” 2017. Web. 14 Dec 2019.

Vancouver:

Hsu C. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. [Internet] [Thesis]. University of Illinois – Chicago; 2017. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/10027/21822.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hsu C. Medical Imaging Techniques for Characterizing Cerebral Angioarchitecture. [Thesis]. University of Illinois – Chicago; 2017. Available from: http://hdl.handle.net/10027/21822

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Hong Kong University of Science and Technology

2. Lam, Alexander Ka Ngai. Characterization of pressure reduction mechanism in treatment of intracranial aneurysm.

Degree: 2014, Hong Kong University of Science and Technology

URL: https://doi.org/10.14711/thesis-b1274352 ; http://repository.ust.hk/ir/bitstream/1783.1-62779/1/th_redirect.html

► Intracranial aneurysm can be treated endoluminally without major surgery by placing embolization coils into the aneurysm or flow diverters across the aneurysm's neck. With these… (more)

▼ Intracranial aneurysm can be treated endoluminally without major surgery by placing embolization coils into the aneurysm or flow diverters across the aneurysm's neck. With these placements, blood flow into the aneurysm is immediately reduced and the aneurysm is occluded in long term. However, clinical studies showed that recurrence risk of aneurysm treated by coils is high and aneurysm is known to rupture after deployment of flow diverters. The rupture risk due to tensional wall stress can be reduced if aneurysmal pressure is reduced with device deployment. In this study, four kinds of mechanisms were hypothesized to affect pressure: flow diverting effect and coagulation effect by flow diverter, and intra-aneurysmal flow reduction effect and coagulation effect with coils. Pressures inside rubber-model aneurysms were characterized with flowing anti-coagulated blood. The analysis showed that the pressure inside aneurysm was only marginally affected when flow diverters were deployed across the aneurysm necks. When blood coagulation capability was restored in the same setup, >10% pressure reductions were induced in 60 minutes or less. The results showed that coagulation in aneurysm is essential for reduction of aneurysmal pressure and rupture risk. Further experiments with packed coils in model aneurysm confirmed that coagulation in aneurysm is essential for aneurysmal pressure reduction. These characterization studies have led to better understanding on pressure behavior within aneurysm after deployment of different treatment device. In clinical practice and treatments, anti-coagulants such as heparin are routinely administered into patient's bloodstream as a means to prevent arterial stenosis. Aneurysmal pressure reduction cannot be effected unless coagulation can be selectively restored in the aneurysm without significantly affecting the heparin's anti-coagulating action in the parent vessel. To meet this need, novel coils coated with a bio-soluble polymer matrix have been developed. Local coagulation is restored inside aneurysm by loading the coating matrix with reversal drugs for anti-coagulants. The effect of the biosoluble drug-loaded coils on the pressure profile was experimentally studied using the aneurysm model with flowing heparinized human blood. Platinum coils were used as control for comparison. The results showed that aneurysmal pressure was reduced by >10% within an hour while only minor reduction was observed in the platinum coil case. These results confirmed that the coagulation-inducing coils can effectively reduce local aneurysmal pressure better than platinum coils. This suggests that risk of re-rupture can be better managed with the new drug-loaded coils when used in combination with flow diverters and stents in the acute treatment of ruptured intracranial aneurysms. This new coil device should address the anti-platelet medication problem as well and be adapted in-vivo for testing in the future.

Subjects/Keywords: Intracranial aneurysms; Treatment; Blood flow; Blood pressure

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lam, A. K. N. (2014). Characterization of pressure reduction mechanism in treatment of intracranial aneurysm. (Thesis). Hong Kong University of Science and Technology. Retrieved from https://doi.org/10.14711/thesis-b1274352 ; http://repository.ust.hk/ir/bitstream/1783.1-62779/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Lam, Alexander Ka Ngai. “Characterization of pressure reduction mechanism in treatment of intracranial aneurysm.” 2014. Thesis, Hong Kong University of Science and Technology. Accessed December 14, 2019. https://doi.org/10.14711/thesis-b1274352 ; http://repository.ust.hk/ir/bitstream/1783.1-62779/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Lam, Alexander Ka Ngai. “Characterization of pressure reduction mechanism in treatment of intracranial aneurysm.” 2014. Web. 14 Dec 2019.

Vancouver:

Lam AKN. Characterization of pressure reduction mechanism in treatment of intracranial aneurysm. [Internet] [Thesis]. Hong Kong University of Science and Technology; 2014. [cited 2019 Dec 14]. Available from: https://doi.org/10.14711/thesis-b1274352 ; http://repository.ust.hk/ir/bitstream/1783.1-62779/1/th_redirect.html.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Lam AKN. Characterization of pressure reduction mechanism in treatment of intracranial aneurysm. [Thesis]. Hong Kong University of Science and Technology; 2014. Available from: https://doi.org/10.14711/thesis-b1274352 ; http://repository.ust.hk/ir/bitstream/1783.1-62779/1/th_redirect.html

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Vanderbilt University

3. Talati, Pratik. Imaging Hippocampal Hemodynamics in Schizophrenia.

Degree: PhD, Neuroscience, 2015, Vanderbilt University

URL: http://etd.library.vanderbilt.edu/available/etd-08132015-191444/ ;

► The hippocampus is a medial temporal lobe structure involved in learning and memory. Several magnetic resonance imaging methods exist to investigate hippocampal structure and function… (more)

Subjects/Keywords: Neuroimaging; Hippocampus; Schizophrenia; Blood Volume; Blood Flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Talati, P. (2015). Imaging Hippocampal Hemodynamics in Schizophrenia. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://etd.library.vanderbilt.edu/available/etd-08132015-191444/ ;

Chicago Manual of Style (16^th Edition):

Talati, Pratik. “Imaging Hippocampal Hemodynamics in Schizophrenia.” 2015. Doctoral Dissertation, Vanderbilt University. Accessed December 14, 2019. http://etd.library.vanderbilt.edu/available/etd-08132015-191444/ ;.

MLA Handbook (7^th Edition):

Talati, Pratik. “Imaging Hippocampal Hemodynamics in Schizophrenia.” 2015. Web. 14 Dec 2019.

Vancouver:

Talati P. Imaging Hippocampal Hemodynamics in Schizophrenia. [Internet] [Doctoral dissertation]. Vanderbilt University; 2015. [cited 2019 Dec 14]. Available from: http://etd.library.vanderbilt.edu/available/etd-08132015-191444/ ;.

Council of Science Editors:

Talati P. Imaging Hippocampal Hemodynamics in Schizophrenia. [Doctoral Dissertation]. Vanderbilt University; 2015. Available from: http://etd.library.vanderbilt.edu/available/etd-08132015-191444/ ;

University of Rochester

4. Bell, Robert D. Cerebral Vascular Dysfunction in Alzheimer’s Disease.

Degree: PhD, 2011, University of Rochester

URL: http://hdl.handle.net/1802/14591

► The neurovascular unit is comprised of brain endothelium, pericytes, vascular smooth muscle cells (VSMC), astrocytes, microglia and neurons. Complex and dynamic communication between the cells… (more)

▼ The neurovascular unit is comprised of brain endothelium, pericytes, vascular smooth muscle cells (VSMC), astrocytes, microglia and neurons. Complex and dynamic communication between the cells of the neurovascular unit is essential for maintaining normal brain function. Recently, the role of cerebral vascular dysfunction has been highlighted in several neurodegenerative disease processes, such as Alzheimer’s disease (AD). Here, I utilized multiple experimental models to test the central hypothesis that cerebral vascular dysfunction can contribute to AD pathogenesis. We found that (1) cerebral vascular dysfunction, mediated by pericyte deficiency in adult mice, can lead to neurodegeneration, (2) molecular changes specifically within brain VSMC can contribute to the development of AD-like pathologies in the cerebral cortex and (3) a known inherited genetic risk factor for AD may contribute to the cerebral vascular damage that is present during disease pathogenesis. First, pericytes play a key role in the development of the cerebral microcirculation, although the exact role of pericytes in the adult brain remains elusive. Using adult viable mice with varying degrees of pericyte deficiency, we show that pericyte loss leads to reduction in brain microcirculation causing chronic perfusion stress and hypoxia, and blood-brain barrier breakdown associated with brain accumulation of vasculotoxic and/or neurotoxic serum proteins. Age-dependent vascular damage in pericyte-deficient mice precedes neuronal degenerative changes, and learning and memory impairment. Thus, pericytes control key neurovascular functions that are necessary for proper neuronal structure and function, and pericyte loss results in progressive age-dependent vascular-mediated neurodegeneration. This study provides proof-of-principle evidence supporting the hypothesis that vascular damage may initiate neurodegenerative disease processes. Next, we investigate the molecular basis of a vascular-specific insult mediated by amyloid -peptide (A) deposition in cerebral vessels, called cerebral amyloid angiopathy, which contributes to AD pathogenesis. Here, we report increased levels of two proteins, serum response factor (SRF) and myocardin (MYOCD), in cerebral VSMC in AD and in two mouse models of AD generates an A non-clearing VSMC phenotype via transactivation of sterol regulatory element binding protein-2, which downregulates low density lipoprotein receptor-related protein-1, a key A clearance receptor. Hypoxia stimulated SRF/MYOCD expression in human cerebral VSMC and in an AD mouse model. We suggest SRF and MYOCD constitute a new transcriptional switch controlling  cerebrovascular clearance and progression of AD. This study supports the hypothesis that molecular changes specifically in vascular cells of the neurovascular unit may contribute to AD pathogenesis. Finally, the apolipoprotein E4 (APOE4) allele is an inherited genetic risk factor for the development of neurological disorders that are associated with neurovascular dysfunction,…

Subjects/Keywords: Neurovascular; Blood Brain Barrier; Cerebral Blood Flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bell, R. D. (2011). Cerebral Vascular Dysfunction in Alzheimer’s Disease. (Doctoral Dissertation). University of Rochester. Retrieved from http://hdl.handle.net/1802/14591

Chicago Manual of Style (16^th Edition):

Bell, Robert D. “Cerebral Vascular Dysfunction in Alzheimer’s Disease.” 2011. Doctoral Dissertation, University of Rochester. Accessed December 14, 2019. http://hdl.handle.net/1802/14591.

MLA Handbook (7^th Edition):

Bell, Robert D. “Cerebral Vascular Dysfunction in Alzheimer’s Disease.” 2011. Web. 14 Dec 2019.

Vancouver:

Bell RD. Cerebral Vascular Dysfunction in Alzheimer’s Disease. [Internet] [Doctoral dissertation]. University of Rochester; 2011. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/1802/14591.

Council of Science Editors:

Bell RD. Cerebral Vascular Dysfunction in Alzheimer’s Disease. [Doctoral Dissertation]. University of Rochester; 2011. Available from: http://hdl.handle.net/1802/14591

University of Utah

5. Leppink, Mary Ann. Relationship between placental site and birth weight of the human infant;.

Degree: MS;, Nursing;, 1979, University of Utah

URL: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/210/rec/1119

► The purpose of this study was to determine whether or not a relationship exists between the uterine placental site and the birth weight of infants… (more)

Subjects/Keywords: Blood Flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Leppink, M. A. (1979). Relationship between placental site and birth weight of the human infant;. (Masters Thesis). University of Utah. Retrieved from http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/210/rec/1119

Chicago Manual of Style (16^th Edition):

Leppink, Mary Ann. “Relationship between placental site and birth weight of the human infant;.” 1979. Masters Thesis, University of Utah. Accessed December 14, 2019. http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/210/rec/1119.

MLA Handbook (7^th Edition):

Leppink, Mary Ann. “Relationship between placental site and birth weight of the human infant;.” 1979. Web. 14 Dec 2019.

Vancouver:

Leppink MA. Relationship between placental site and birth weight of the human infant;. [Internet] [Masters thesis]. University of Utah; 1979. [cited 2019 Dec 14]. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/210/rec/1119.

Council of Science Editors:

Leppink MA. Relationship between placental site and birth weight of the human infant;. [Masters Thesis]. University of Utah; 1979. Available from: http://content.lib.utah.edu/cdm/singleitem/collection/etd1/id/210/rec/1119

Penn State University

6. Stanhewicz, Anna E. LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN.

Degree: MS, Physiology, 2011, Penn State University

URL: https://etda.libraries.psu.edu/catalog/12355

► Reflex cutaneous vasodilation (VD) is attenuated in aged skin, potentially resulting in decreased heat loss during heat exposure. Constitutive NO-synthase (NOS) is necessary for full… (more)

Subjects/Keywords: tetrahydrobiopterin; skin blood flow; aging

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stanhewicz, A. E. (2011). LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN. (Masters Thesis). Penn State University. Retrieved from https://etda.libraries.psu.edu/catalog/12355

Chicago Manual of Style (16^th Edition):

Stanhewicz, Anna E. “LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN.” 2011. Masters Thesis, Penn State University. Accessed December 14, 2019. https://etda.libraries.psu.edu/catalog/12355.

MLA Handbook (7^th Edition):

Stanhewicz, Anna E. “LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN.” 2011. Web. 14 Dec 2019.

Vancouver:

Stanhewicz AE. LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN. [Internet] [Masters thesis]. Penn State University; 2011. [cited 2019 Dec 14]. Available from: https://etda.libraries.psu.edu/catalog/12355.

Council of Science Editors:

Stanhewicz AE. LOCAL TETRAHYDROBIOPTERIN AUGMENTS REFLEX CUTANEOUS VASODILATION IN AGED HUMAN SKIN. [Masters Thesis]. Penn State University; 2011. Available from: https://etda.libraries.psu.edu/catalog/12355

Montana State University

7. Mountain, Richard Dale. Correlation of blood flow in a packed bed of glass spheres.

Degree: College of Engineering, 1973, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/5773

Subjects/Keywords: Blood flow.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mountain, R. D. (1973). Correlation of blood flow in a packed bed of glass spheres. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5773

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mountain, Richard Dale. “Correlation of blood flow in a packed bed of glass spheres.” 1973. Thesis, Montana State University. Accessed December 14, 2019. https://scholarworks.montana.edu/xmlui/handle/1/5773.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mountain, Richard Dale. “Correlation of blood flow in a packed bed of glass spheres.” 1973. Web. 14 Dec 2019.

Vancouver:

Mountain RD. Correlation of blood flow in a packed bed of glass spheres. [Internet] [Thesis]. Montana State University; 1973. [cited 2019 Dec 14]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5773.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mountain RD. Correlation of blood flow in a packed bed of glass spheres. [Thesis]. Montana State University; 1973. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5773

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana State University

8. Fenton, Bruce Miles. Flow of human blood through fabricated replicas of microvascular bifurcations.

Degree: College of Engineering, 1975, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/5139

Subjects/Keywords: Blood flow.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fenton, B. M. (1975). Flow of human blood through fabricated replicas of microvascular bifurcations. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5139

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fenton, Bruce Miles. “Flow of human blood through fabricated replicas of microvascular bifurcations.” 1975. Thesis, Montana State University. Accessed December 14, 2019. https://scholarworks.montana.edu/xmlui/handle/1/5139.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fenton, Bruce Miles. “Flow of human blood through fabricated replicas of microvascular bifurcations.” 1975. Web. 14 Dec 2019.

Vancouver:

Fenton BM. Flow of human blood through fabricated replicas of microvascular bifurcations. [Internet] [Thesis]. Montana State University; 1975. [cited 2019 Dec 14]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5139.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fenton BM. Flow of human blood through fabricated replicas of microvascular bifurcations. [Thesis]. Montana State University; 1975. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5139

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana State University

9. Larson, Lara. Changes in the flow properties of human blood.

Degree: College of Engineering, 1973, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/5414

Subjects/Keywords: Blood flow.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Larson, L. (1973). Changes in the flow properties of human blood. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Larson, Lara. “Changes in the flow properties of human blood.” 1973. Thesis, Montana State University. Accessed December 14, 2019. https://scholarworks.montana.edu/xmlui/handle/1/5414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Larson, Lara. “Changes in the flow properties of human blood.” 1973. Web. 14 Dec 2019.

Vancouver:

Larson L. Changes in the flow properties of human blood. [Internet] [Thesis]. Montana State University; 1973. [cited 2019 Dec 14]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5414.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Larson L. Changes in the flow properties of human blood. [Thesis]. Montana State University; 1973. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5414

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana State University

10. Shah, Bharat Ochhavlal. Some of the characteristics of steady and oscillatory blood flow.

Degree: College of Engineering, 1978, Montana State University

URL: https://scholarworks.montana.edu/xmlui/handle/1/4565

Subjects/Keywords: Blood flow.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shah, B. O. (1978). Some of the characteristics of steady and oscillatory blood flow. (Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/4565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Shah, Bharat Ochhavlal. “Some of the characteristics of steady and oscillatory blood flow.” 1978. Thesis, Montana State University. Accessed December 14, 2019. https://scholarworks.montana.edu/xmlui/handle/1/4565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Shah, Bharat Ochhavlal. “Some of the characteristics of steady and oscillatory blood flow.” 1978. Web. 14 Dec 2019.

Vancouver:

Shah BO. Some of the characteristics of steady and oscillatory blood flow. [Internet] [Thesis]. Montana State University; 1978. [cited 2019 Dec 14]. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Shah BO. Some of the characteristics of steady and oscillatory blood flow. [Thesis]. Montana State University; 1978. Available from: https://scholarworks.montana.edu/xmlui/handle/1/4565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana Tech

11. Gallo, Tyler L. CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE.

Degree: MS, 2014, Montana Tech

URL: https://scholarworks.umt.edu/etd/4292

► We investigated the role of intramuscular pressure on the blood volumes delivered to working muscle during contractions spanning the entire range of force output that… (more)

▼ We investigated the role of intramuscular pressure on the blood volumes delivered to working muscle during contractions spanning the entire range of force output that could be elicited from our subjects. Our subjects included four male (age = 22 ± 14 yr, mass = 63 ± 1.5 kg) and four female (age = 23 ± 9 yr, mass = 81.4 ± 5.6 kg). Vascular occlusion is thought to occur at similar pressures between sexes, but these pressures are achieved at different fractions of the male vs female maximum voluntary contraction. We therefore used a triplex capable pulsed Doppler ultrasound to obtain non-invasive measures of blood velocity and femoral artery diameter during single leg knee extension exercise performed by male (n = 4) and female (n = 4) subjects on an instrumented custom ergometer. We observed that greater periods of muscle inactivity between subsequent analysis (i.e. lower duty cycles), provided enhanced opportunity for circulatory based clearance by as much as 60 % and 64 % in males and females respectively. The forces subjects applied to the ergometer were measured via single-element strain gauges as the subjects adhered to a constant investigator-imposed cadence. Subjects performed bouts of knee extension exercise ranging from no-external imposed force, up to the level that could be performed for only three consecutive contractions (male = 524.66 ± 71.24 N vs female = 326.90 ± 115.75 N) while matching the experimental cadence. Resistance is controlled by manual Monarch turns and cadence is controlled by dual column LED array. We measured peak oxygen uptake (male = 26.90 ± 5.17 ml O2 kg-1 min-1 vs female = 19.57 ± 2.47 ml O2 kg-1 min-1) and surface EMG to determine the forces necessary to elicit anaerobic metabolism and the onset of compensatory neuromuscular recruitment an indicator, respectively. These experiments determined whether short-duration performance decrements are an issue of oxygen availability or related to clearance of metabolic byproducts elicited by muscle contraction.

Subjects/Keywords: Femoral Blood Flow; Muscle Performance

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gallo, T. L. (2014). CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE. (Masters Thesis). Montana Tech. Retrieved from https://scholarworks.umt.edu/etd/4292

Chicago Manual of Style (16^th Edition):

Gallo, Tyler L. “CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE.” 2014. Masters Thesis, Montana Tech. Accessed December 14, 2019. https://scholarworks.umt.edu/etd/4292.

MLA Handbook (7^th Edition):

Gallo, Tyler L. “CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE.” 2014. Web. 14 Dec 2019.

Vancouver:

Gallo TL. CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE. [Internet] [Masters thesis]. Montana Tech; 2014. [cited 2019 Dec 14]. Available from: https://scholarworks.umt.edu/etd/4292.

Council of Science Editors:

Gallo TL. CONTINUOUS MEASURES OF MUSCLE BLOOD FLOW DURING ALL-OUT DYNAMIC EXERCISE. [Masters Thesis]. Montana Tech; 2014. Available from: https://scholarworks.umt.edu/etd/4292

East Carolina University

12. Kehe, Sarah. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.

Degree: 2012, East Carolina University

URL: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=14832

► Mean arterial pressure (MAP) is regulated through changes in cardiac output (Q) and total peripheral resistance (TPR) where Q = heart rate (HR) x stroke… (more)

Subjects/Keywords: Blood flow – Measurement; Aerobic exercises

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kehe, S. (2012). VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. (Masters Thesis). East Carolina University. Retrieved from http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=14832

Chicago Manual of Style (16^th Edition):

Kehe, Sarah. “VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.” 2012. Masters Thesis, East Carolina University. Accessed December 14, 2019. http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=14832.

MLA Handbook (7^th Edition):

Kehe, Sarah. “VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.” 2012. Web. 14 Dec 2019.

Vancouver:

Kehe S. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. [Internet] [Masters thesis]. East Carolina University; 2012. [cited 2019 Dec 14]. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=14832.

Council of Science Editors:

Kehe S. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. [Masters Thesis]. East Carolina University; 2012. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=14832

13. Smith, Joshua Richard. Sex differences in cardiopulmonary responses to exercise.

Degree: PhD, Department of Kinesiology, 2017, Kansas State University

URL: http://hdl.handle.net/2097/35410

► The overall aim of this dissertation is to further understand sex differences in the cardiopulmonary responses during exercise in younger and older individuals. Emphasis is… (more)

Subjects/Keywords: Blood flow; Metaboreflex; Sex differences

1 more image…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Smith, J. R. (2017). Sex differences in cardiopulmonary responses to exercise. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/35410

Chicago Manual of Style (16^th Edition):

Smith, Joshua Richard. “Sex differences in cardiopulmonary responses to exercise.” 2017. Doctoral Dissertation, Kansas State University. Accessed December 14, 2019. http://hdl.handle.net/2097/35410.

MLA Handbook (7^th Edition):

Smith, Joshua Richard. “Sex differences in cardiopulmonary responses to exercise.” 2017. Web. 14 Dec 2019.

Vancouver:

Smith JR. Sex differences in cardiopulmonary responses to exercise. [Internet] [Doctoral dissertation]. Kansas State University; 2017. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/2097/35410.

Council of Science Editors:

Smith JR. Sex differences in cardiopulmonary responses to exercise. [Doctoral Dissertation]. Kansas State University; 2017. Available from: http://hdl.handle.net/2097/35410

Cal Poly

14. Hinsdale, Taylor A. Laser Speckle Imaging: A Quantitative Tool for Flow Analysis.

Degree: MS, Biomedical and General Engineering, 2014, Cal Poly

URL: https://digitalcommons.calpoly.edu/theses/1251 ; 10.15368/theses.2014.96

► Laser speckle imaging, often referred to as laser speckle contrast analysis (LASCA), has been sought after as a quasi-real-time, full-field, flow visualization method. It… (more)

Subjects/Keywords: Laser; Speckle; Quantitative; Flow; Blood

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hinsdale, T. A. (2014). Laser Speckle Imaging: A Quantitative Tool for Flow Analysis. (Masters Thesis). Cal Poly. Retrieved from https://digitalcommons.calpoly.edu/theses/1251 ; 10.15368/theses.2014.96

Chicago Manual of Style (16^th Edition):

Hinsdale, Taylor A. “Laser Speckle Imaging: A Quantitative Tool for Flow Analysis.” 2014. Masters Thesis, Cal Poly. Accessed December 14, 2019. https://digitalcommons.calpoly.edu/theses/1251 ; 10.15368/theses.2014.96.

MLA Handbook (7^th Edition):

Hinsdale, Taylor A. “Laser Speckle Imaging: A Quantitative Tool for Flow Analysis.” 2014. Web. 14 Dec 2019.

Vancouver:

Hinsdale TA. Laser Speckle Imaging: A Quantitative Tool for Flow Analysis. [Internet] [Masters thesis]. Cal Poly; 2014. [cited 2019 Dec 14]. Available from: https://digitalcommons.calpoly.edu/theses/1251 ; 10.15368/theses.2014.96.

Council of Science Editors:

Hinsdale TA. Laser Speckle Imaging: A Quantitative Tool for Flow Analysis. [Masters Thesis]. Cal Poly; 2014. Available from: https://digitalcommons.calpoly.edu/theses/1251 ; 10.15368/theses.2014.96

Rutgers University

15. Vahidkhah, Koohyar, 1986-. Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow.

Degree: PhD, Mechanical and Aerospace Engineering, 2015, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/48706/

► Computational modeling and simulation is considered to study the concurrent multiscale/multiphysics phenomena associated with cellular/particulate transport in microcirculatory blood flow. The model integrates microhydrodynamics of… (more)

▼ Computational modeling and simulation is considered to study the concurrent multiscale/multiphysics phenomena associated with cellular/particulate transport in microcirculatory blood flow. The model integrates microhydrodynamics of different blood cells, complexity of vascular geometry, and nanoscale adhesive interactions. A finite element method (FEM) is used to model the cell membrane deformation with high accuracy, and is coupled to the bulk flow motion via a front-tracking method. The geometric complexities are simulated using a sharp-interface immersed boundary method, and the molecular adhesion is coarse-grained via a Monte Carlo method. The following sequence of problems is addressed: (a) Hydrodynamic interaction between a platelet and a red blood cell (RBC) in a dilute suspension: 3D simulations of pairwise hydrodynamic interaction between a platelet and an RBC in a wall-bounded shear flow are conducted. The effects of different dynamics of the RBC, namely tank-treading and tumbling, and the proximity to the wall on platelet trajectories are quantified. Based on the numerical results, a mechanism of continual platelet drift towards the vessel wall is proposed. (b) Platelet transport and dynamics in blood flow: 3D simulations are considered to study the transport of platelets in semi-dense suspension of flowing RBCs. It is found that the local microstructure of RBC suspension provides a fast margination mechanism for platelets to drift towards the blood vessel wall. It is also shown that the anisotropic diffusion of platelets contributes to the formation of platelet clusters, and may act as a hydrodynamic precursor to blood clot formation. (c) Microparticle shape effects on their transport and dynamics in blood flow: The shape effect of microscale targeting drug carriers modeled as platelet-sized microparticles on their margination, near-wall dynamics, and adhesion is quantified and explained by individual particle dynamics and interaction with RBCs. It is shown that the particle shape has entirely different effects on different stages of margination/adhesion cascade. It is suggested that the local hemorheological conditions of the targeted site should be taken into account while selecting the optimum shape for microvascular drug carriers. (d) Blood flow in stenosed microvessels: 3D simulations of cellular motion through stenosed microvessels are considered. The Fahraeus-Lindqvist effect is shown to be significantly enhanced, due to the asymmetric distribution of the RBCs caused by the stenosis geometry. Such asymmetry together with the discrete motion of cells are demonstrated to cause an asymmetry in the average as well as the time-dependent flow characteristics along the length of stenosis. It is concluded that the flow physics and its physiological consequences are significantly different in micro- versus macrovascular stenosis. (e) Adhesion of microparticles in microvessels – role of RBCs and microparticle deformability: 3D simulations of the adhesion of deformable drug carrier particles in the… Advisors/Committee Members: Bagchi, Prosenjit (chair).

Subjects/Keywords: Computer simulation; Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vahidkhah, Koohyar, 1. (2015). Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/48706/

Chicago Manual of Style (16^th Edition):

Vahidkhah, Koohyar, 1986-. “Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow.” 2015. Doctoral Dissertation, Rutgers University. Accessed December 14, 2019. https://rucore.libraries.rutgers.edu/rutgers-lib/48706/.

MLA Handbook (7^th Edition):

Vahidkhah, Koohyar, 1986-. “Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow.” 2015. Web. 14 Dec 2019.

Vancouver:

Vahidkhah, Koohyar 1. Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow. [Internet] [Doctoral dissertation]. Rutgers University; 2015. [cited 2019 Dec 14]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48706/.

Council of Science Editors:

Vahidkhah, Koohyar 1. Three-dimensional computational simulation of multiscale multiphysics cellular/particulate processes in microcirculatory blood flow. [Doctoral Dissertation]. Rutgers University; 2015. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/48706/

Michigan State University

16. Radawski, Daniel Philip, 1944-. Role of cations and osmolality in local blood flow regulation and in hemorrhage.

Degree: PhD, Department of Physiology, 1971, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:37343

Subjects/Keywords: Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Radawski, Daniel Philip, 1. (1971). Role of cations and osmolality in local blood flow regulation and in hemorrhage. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:37343

Chicago Manual of Style (16^th Edition):

Radawski, Daniel Philip, 1944-. “Role of cations and osmolality in local blood flow regulation and in hemorrhage.” 1971. Doctoral Dissertation, Michigan State University. Accessed December 14, 2019. http://etd.lib.msu.edu/islandora/object/etd:37343.

MLA Handbook (7^th Edition):

Radawski, Daniel Philip, 1944-. “Role of cations and osmolality in local blood flow regulation and in hemorrhage.” 1971. Web. 14 Dec 2019.

Vancouver:

Radawski, Daniel Philip 1. Role of cations and osmolality in local blood flow regulation and in hemorrhage. [Internet] [Doctoral dissertation]. Michigan State University; 1971. [cited 2019 Dec 14]. Available from: http://etd.lib.msu.edu/islandora/object/etd:37343.

Council of Science Editors:

Radawski, Daniel Philip 1. Role of cations and osmolality in local blood flow regulation and in hemorrhage. [Doctoral Dissertation]. Michigan State University; 1971. Available from: http://etd.lib.msu.edu/islandora/object/etd:37343

Michigan State University

17. Porteous, William M. Hemorheological aspects of reduced osmolarity.

Degree: MS, Dept. of Chemical Engineering, 1971, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:13669

Subjects/Keywords: Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Porteous, W. M. (1971). Hemorheological aspects of reduced osmolarity. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:13669

Chicago Manual of Style (16^th Edition):

Porteous, William M. “Hemorheological aspects of reduced osmolarity.” 1971. Masters Thesis, Michigan State University. Accessed December 14, 2019. http://etd.lib.msu.edu/islandora/object/etd:13669.

MLA Handbook (7^th Edition):

Porteous, William M. “Hemorheological aspects of reduced osmolarity.” 1971. Web. 14 Dec 2019.

Vancouver:

Porteous WM. Hemorheological aspects of reduced osmolarity. [Internet] [Masters thesis]. Michigan State University; 1971. [cited 2019 Dec 14]. Available from: http://etd.lib.msu.edu/islandora/object/etd:13669.

Council of Science Editors:

Porteous WM. Hemorheological aspects of reduced osmolarity. [Masters Thesis]. Michigan State University; 1971. Available from: http://etd.lib.msu.edu/islandora/object/etd:13669

Michigan State University

18. Brace, Robert Allen, 1948-. Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow.

Degree: MS, Dept. of Chemical Engineering, 1971, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:7096

Subjects/Keywords: Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Brace, Robert Allen, 1. (1971). Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:7096

Chicago Manual of Style (16^th Edition):

Brace, Robert Allen, 1948-. “Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow.” 1971. Masters Thesis, Michigan State University. Accessed December 14, 2019. http://etd.lib.msu.edu/islandora/object/etd:7096.

MLA Handbook (7^th Edition):

Brace, Robert Allen, 1948-. “Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow.” 1971. Web. 14 Dec 2019.

Vancouver:

Brace, Robert Allen 1. Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow. [Internet] [Masters thesis]. Michigan State University; 1971. [cited 2019 Dec 14]. Available from: http://etd.lib.msu.edu/islandora/object/etd:7096.

Council of Science Editors:

Brace, Robert Allen 1. Hemodialysis studies of the effects of low blood potassium and low blood magnesium on skeletal muscle vascular resistance to blood flow. [Masters Thesis]. Michigan State University; 1971. Available from: http://etd.lib.msu.edu/islandora/object/etd:7096

Queens University

19. Bravo, Michael Francis. Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes .

Degree: Kinesiology and Health Studies, 2012, Queens University

URL: http://hdl.handle.net/1974/7002

► Background: Exercise is widely recognized as the cornerstone of management of type II diabetes (T2D). However, it is also known that people with T2D have… (more)

▼ Background: Exercise is widely recognized as the cornerstone of management of type II diabetes (T2D). However, it is also known that people with T2D have poor adherence to exercise regimens, which is largely thought to be because of poor exercise tolerance. Recent studies have suggested that this exercise intolerance may be caused by a reduction in exercising muscle blood flow. One physiological mechanism which could potentially contribute is the muscle metaboreflex (MMR). This mechanism is thought to be a pressure-based flow-improving mechanism, but as a result of reduced efficacy of vasodilators and sympatholytic agents, might in fact be restraining the flow-improvement in persons with T2D. Hypothesis: Persons with T2D would not improve exercising muscle blood flow upon MMR activation. This absence of flow-improvement will be due to an augmented vasoconstriction in the exercising muscle. Methods: T2D (n=7) and CTL (n=6) participants performed rhythmic forearm handgrip exercise at an intensity equivalent to 20% MVC for 9 minutes with and without the application of ischemic plantar flexion (IPF). Forearm blood flow (FBF), mean arterial pressure (MAP), cardiac output (CO), heart rate (HR), total peripheral resistance (TPR) and forearm vascular conductance (FVK) were quantified for the last thirty seconds of each of four time points during the protocol. Plasma norepinephrine was measured via deep venous and arterialized venous blood sampling. Results: Steady state exercising FBF was increased in CTL but not in T2D during MMR activation (mean ± SE mL/min: CTLControl 161.16 ± 5.95, CTLMMR 212.72 ± 9.49, T2DControl 156.71 ± 13.08, T2DMMR 144.22 ± 10.55). This occurred despite similar increases in MAP, CO, HR, and TPR (across groups and treatment conditions, NS). FVK increased in CTL during the MMR protocol compared to the Control protocol, but decreased in the T2D group using the same comparison (mean ± SE mL/min/100 mm Hg: CTLControl 144.74 ± 5.63, CTLMMR 176.76 ± 11.99, T2DControl 143.29 ± 13.44, T2DMMR 103.53 ± 8.44). Conclusions: In the exercise model utilized, persons with T2D do not demonstrate the MMR-induced flow improvement seen in CTL. This impaired muscle blood flow in T2D is the result of MMR induced exercising limb vasoconstriction.

Subjects/Keywords: Blood Flow; Type 2 Diabetes

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bravo, M. F. (2012). Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/7002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bravo, Michael Francis. “Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes .” 2012. Thesis, Queens University. Accessed December 14, 2019. http://hdl.handle.net/1974/7002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bravo, Michael Francis. “Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes .” 2012. Web. 14 Dec 2019.

Vancouver:

Bravo MF. Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes . [Internet] [Thesis]. Queens University; 2012. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/1974/7002.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bravo MF. Metaboreflex-Induced Flow Improvement is Absent in Older Males With Type II Diabetes . [Thesis]. Queens University; 2012. Available from: http://hdl.handle.net/1974/7002

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brunel University

20. Trangmar, Steven John. Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism.

Degree: PhD, 2015, Brunel University

URL: http://bura.brunel.ac.uk/handle/2438/10609 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646264

► Heat stress and dehydration pose a severe challenge to physiological function and the capability to perform physical work. There is, however, limited knowledge on the… (more)

▼ Heat stress and dehydration pose a severe challenge to physiological function and the capability to perform physical work. There is, however, limited knowledge on the regional haemodynamic and metabolic responses to strenuous exercise in environmentally stressful conditions. The primary aim of this thesis was to examine whether dehydration and heat stress compromise brain, muscle and systemic blood flow and metabolism, and whether depressed brain and muscle oxygen delivery underpin reduced exercise capacity during graded incremental and prolonged exercise. This thesis makes an original contribution to the knowledge by showing for the first time that dehydration markedly accelerates the decline in cerebral blood flow during maximal incremental (Chapter 4) and prolonged sub-maximal exercise (Chapter 5) in the heat. Cerebral metabolism, however, is preserved by compensatory increases in substrate extraction. Falling carbon dioxide tension underpinned the decline in CBF. However, a distinct regional distribution of blood flow across the head was observed, suggesting that different mechanisms are responsible for the regulation of regional blood flow within the head. A reduced cerebral metabolism is therefore an unlikely factor explaining the compromised exercise capacity in physiologically stressful hot environments. Rather, restrictions in active muscle blood flow and oxygen supply, which are not apparent during sub-maximal exercise, may explain the reduced maximal aerobic power in heat stressed conditions. For the first time we have manipulated skin and core temperature to show that combined internal and skin hyperthermia reduces maximal aerobic power in association with restrictions in limb, brain and systemic blood flow and skeletal muscle metabolism (Chapter 6). Overall, the findings of the present thesis provide novel information on how circulatory limitations across contracting skeletal muscle, brain and systemic tissues and organs might underpin the impairment in exercise capacity in physiologically taxing environments evoking significant dehydration and hyperthermia.

Subjects/Keywords: Exercise; Cardiovascular physiology; Cerebral blood flow; Blood flow regulation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Trangmar, S. J. (2015). Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism. (Doctoral Dissertation). Brunel University. Retrieved from http://bura.brunel.ac.uk/handle/2438/10609 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646264

Chicago Manual of Style (16^th Edition):

Trangmar, Steven John. “Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism.” 2015. Doctoral Dissertation, Brunel University. Accessed December 14, 2019. http://bura.brunel.ac.uk/handle/2438/10609 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646264.

MLA Handbook (7^th Edition):

Trangmar, Steven John. “Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism.” 2015. Web. 14 Dec 2019.

Vancouver:

Trangmar SJ. Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism. [Internet] [Doctoral dissertation]. Brunel University; 2015. [cited 2019 Dec 14]. Available from: http://bura.brunel.ac.uk/handle/2438/10609 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646264.

Council of Science Editors:

Trangmar SJ. Circulatory limitations to exercise capacity in humans : the impact of heat stress and dehydration on brain and muscle blood flow and metabolism. [Doctoral Dissertation]. Brunel University; 2015. Available from: http://bura.brunel.ac.uk/handle/2438/10609 ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.646264

East Carolina University

21. Kehe, Sarah. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.

Degree: 2012, East Carolina University

URL: http://hdl.handle.net/10342/3951

► Mean arterial pressure (MAP) is regulated through changes in cardiac output (Q) and total peripheral resistance (TPR), where Q = heart rate (HR) x stroke… (more)

Subjects/Keywords: Kinesiology; Blood flow; Exercise; Popliteal; Blood flow – Measurement; Aerobic exercises

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kehe, S. (2012). VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. (Thesis). East Carolina University. Retrieved from http://hdl.handle.net/10342/3951

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kehe, Sarah. “VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.” 2012. Thesis, East Carolina University. Accessed December 14, 2019. http://hdl.handle.net/10342/3951.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kehe, Sarah. “VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING.” 2012. Web. 14 Dec 2019.

Vancouver:

Kehe S. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. [Internet] [Thesis]. East Carolina University; 2012. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/10342/3951.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kehe S. VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING. [Thesis]. East Carolina University; 2012. Available from: http://hdl.handle.net/10342/3951

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Waterloo

22. Oteng-Amoako, Afua. Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants.

Degree: 2013, University of Waterloo

URL: http://hdl.handle.net/10012/7975

► Introduction: Oxygen delivery, or utilization, is a function of retinal blood flow and blood oxygen saturation. The retinal pigment epithelium (RPE), in particular, has been… (more)

▼ Introduction: Oxygen delivery, or utilization, is a function of retinal blood flow and blood oxygen saturation. The retinal pigment epithelium (RPE), in particular, has been shown to have the highest levels of metabolic activity within the human body. Oxygen delivery is therefore of extreme importance to the maintenance of the health and integrity of the retina. Animal models presuppose that the oxygen tension in the retina is highest in the innermost layers at the level of the choriocapillaris, less in the photoreceptors and further decreases throughout the outer retinal structures. The choroid provides by far the largest component of the oxygen for consumption by the photoreceptors. A lack of oxygen stores in the inner retina therefore makes a constant supply crucial for its normal functioning. Blood flow dysfunction and subsequent hypoxia are both a feature in the pathogenesis of several major ocular diseases such as retinopathy of prematurity (ROP), age-related macular degeneration (ARMD), diabetic retinopathy (DR) and glaucoma. The development of methods to measure retinal blood flow and blood oxygen saturation is crucial to improve understanding of the patho-physiology of major ocular diseases. Purpose: The aims of this work were, firstly, to determine the least variable (range ± standard deviation) wavelength combination (610/548, 600/569 and 605/586) and subsequent ODR with the prototype HRC device. Secondly, using the ODR with the lowest measurement variability, we sought to quantify retinal blood SO2 in arterioles and venules and investigate the relationship between retinal blood SO2 and total retinal blood flow (TRBF) in response to stepwise changes in PETO2 in healthy participants. Retinal blood SO2 and TRBF were assessed using the IRIS HRC (Photon etc. Inc. Montreal, Canada) and the RTvue Doppler Fourier Domain OCT (Optovue Inc, Freemont, CA) instruments, respectively. Methods: Ten healthy participants between the ages of 23 and 37, with an average age of 28.3 years were evaluated in two descriptive cross-sectional studies. Two gas provocation protocols; hyperoxia (end-tidal oxygen; PETO2 of 100, 200, 300, 400mmHg) and hypoxia (PETO2 of 100, 80, 60, 50mmHg) were administered in a fixed sequential order. In each phase of gas provocation (via modulation of PETO2), retinal blood SO2 and TRBF measurements were acquired with the HRC and Doppler FD-OCT. The precise and repeated control of the partial end tidal pressures of oxygen (PETO2) and carbon dioxide (PETCO2) over the pre-determined phase duration, irrespective of the individuals’ respiratory rate, was made possible with the RespirAct (Thornhill Research Inc., Toronto, Canada); a sequential re-breathing gas delivery Results: In arterioles, the group range (±SD) of ODR values for baseline measurements (PETO2 of 100mmHg) was 0.169±0.061 for the 605/586 wavelength combination, 0.371±0.099 for the 600/569 wavelength combination and 0.340±0.104 for the 610/548 wavelength combination. In venules, the group range (±SD) of ODR values was 0.600±0.198…

Subjects/Keywords: Retinal blood flow; Total Retinal Blood Flow; Oxygen saturation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Oteng-Amoako, A. (2013). Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/7975

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Oteng-Amoako, Afua. “Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants.” 2013. Thesis, University of Waterloo. Accessed December 14, 2019. http://hdl.handle.net/10012/7975.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Oteng-Amoako, Afua. “Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants.” 2013. Web. 14 Dec 2019.

Vancouver:

Oteng-Amoako A. Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants. [Internet] [Thesis]. University of Waterloo; 2013. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/10012/7975.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Oteng-Amoako A. Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants. [Thesis]. University of Waterloo; 2013. Available from: http://hdl.handle.net/10012/7975

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

The Ohio State University

23. Sundararajapuram, Sundararajan Sadagopan. The analysis of the spectral characteristics of disturbed blood flow.

Degree: PhD, Graduate School, 1977, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487063539785694

Subjects/Keywords: Engineering; Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sundararajapuram, S. S. (1977). The analysis of the spectral characteristics of disturbed blood flow. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1487063539785694

Chicago Manual of Style (16^th Edition):

Sundararajapuram, Sundararajan Sadagopan. “The analysis of the spectral characteristics of disturbed blood flow.” 1977. Doctoral Dissertation, The Ohio State University. Accessed December 14, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487063539785694.

MLA Handbook (7^th Edition):

Sundararajapuram, Sundararajan Sadagopan. “The analysis of the spectral characteristics of disturbed blood flow.” 1977. Web. 14 Dec 2019.

Vancouver:

Sundararajapuram SS. The analysis of the spectral characteristics of disturbed blood flow. [Internet] [Doctoral dissertation]. The Ohio State University; 1977. [cited 2019 Dec 14]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487063539785694.

Council of Science Editors:

Sundararajapuram SS. The analysis of the spectral characteristics of disturbed blood flow. [Doctoral Dissertation]. The Ohio State University; 1977. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1487063539785694

University of Georgia

24. Olive, Jennifer Lee. The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals.

Degree: PhD, Exercise Science, 2002, University of Georgia

URL: http://purl.galileo.usg.edu/uga_etd/olive_jennifer_l_200212_phd

► High rates of muscle fatigue and vascular and muscle atrophy occur in spinal cord injured (SCI) individuals. The cause and effect of vascular atrophy in… (more)

▼ High rates of muscle fatigue and vascular and muscle atrophy occur in spinal cord injured (SCI) individuals. The cause and effect of vascular atrophy in SCI individuals is not known. The purposes of this study were to determine if vascular atrophy was related to muscle atrophy and if increased muscle fatigue was related to altered blood flow in SCI individuals. Blood flow was measured in the femoral artery using Doppler ultrasound and muscle mass was determined by magnetic resonance imaging in nine complete, chronic SCI individuals and eight age- and weight-matched able bodied (AB) subjects. Blood flow was determined during cuff occlusion and three different electrical stimulation periods. Electrical stimulation of the quadriceps muscles was conducted to elicit similar activated muscle mass in both groups. Muscle fatigue was determined for each electrical stimulation period. SCI individuals had smaller muscle cross sectional areas (37%, p = 0.001) and volumes (38%, p = 0.001) than AB. SCI individuals had smaller diameter size (37%, p < 0.001) and maximal flows following cuff ischemia (40%, p < 0.001) than AB individuals. Vessel diameter and maximal flow responses to ischemia and exercise, when normalized to muscle volume, were not different between groups. Muscle fatigue was significantly greater (3-8 fold, p =0.001) in the SCI versus the AB individuals. A prolonged half time to peak blood flow at the beginning of exercise (5 fold, p = 0.001) was found in the SCI versus the AB group consistent with reduced oxidative capacity. Half time to recovery after cuff ischemia (p = 0.048) and exercise (p = 0.009) was prolonged in SCI compared to AB individuals consistent with impaired vascular control. In summary, vascular restructuring appears to be closely linked to muscle atrophy in SCI individuals. The magnitude of muscle blood flow to electrical stimulation did not explain muscle fatigue in SCI individuals. Blood flow response at the onset of exercise was delayed; suggesting the ability to increase blood flow to match demand may be a limiting factor, rather than the magnitude of the blood flow response. A prolonged time to recovery of blood flow may indicate decreased vessel reactivity. Advisors/Committee Members: Kevin McCully.

Subjects/Keywords: Muscle blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Olive, J. L. (2002). The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals. (Doctoral Dissertation). University of Georgia. Retrieved from http://purl.galileo.usg.edu/uga_etd/olive_jennifer_l_200212_phd

Chicago Manual of Style (16^th Edition):

Olive, Jennifer Lee. “The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals.” 2002. Doctoral Dissertation, University of Georgia. Accessed December 14, 2019. http://purl.galileo.usg.edu/uga_etd/olive_jennifer_l_200212_phd.

MLA Handbook (7^th Edition):

Olive, Jennifer Lee. “The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals.” 2002. Web. 14 Dec 2019.

Vancouver:

Olive JL. The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals. [Internet] [Doctoral dissertation]. University of Georgia; 2002. [cited 2019 Dec 14]. Available from: http://purl.galileo.usg.edu/uga_etd/olive_jennifer_l_200212_phd.

Council of Science Editors:

Olive JL. The effects of vascular remodeling and blood flow on muscle fatigue during exercise in spinal cord injured individuals. [Doctoral Dissertation]. University of Georgia; 2002. Available from: http://purl.galileo.usg.edu/uga_etd/olive_jennifer_l_200212_phd

Texas A&M University

25. Kim, Taehong. Thermal study of vulnerable atherosclerotic plaque.

Degree: 2009, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2541

► Atherosclerotic plaques with high probability of rupture show the presence of a hot spot due to the accumulation of inflammatory cells. This study utilizes two… (more)

▼ Atherosclerotic plaques with high probability of rupture show the presence of a hot spot due to the accumulation of inflammatory cells. This study utilizes two and three dimensional (2-D and 3-D) arterial geometries containing an atherosclerotic plaque experiencing different levels of inflammation and uses models of heat transfer analysis to determine the temperature distribution in the plaque region. The 2-D studies consider three different vessel geometries: a stenotic straight artery, a bending artery and an arterial bifurcation which model a human aorta, a coronary artery and a carotid bifurcation, respectively. The 3-D model considers a stenotic straight artery using realistic and simplified geometries. Three different blood flow cases are considered: steady-state, transient state and blood flow reduction. In the 3-D model, thermal stress produced by local inflammation is estimated to determine the effect of inflammation over plaque stability. For fluid flow and heat transfer analysis, Navier-Stokes equations and energy equation are solved; for structural analysis, the governing equations are expressed in terms of equilibrium equation, constitutive equation, and compatibility condition, which are are solved using the multi-physics software COMSOL 3.3 (COMSOL, Inc.). Our results indicate that the best location to measure plaque temperature in the presence of blood flow is recommended between the middle and the far edge of the plaque. The blood flow reduction leads to a non-uniform temperature increase ranged from 0.1 to 0.25 °C in the plaque/lumen interface. In 3-D realistic model, the multiple measuring points must be considered to decrease the potential error in temperature measurement even within 1 or 2 mm at centerline region of plaque. The most highly thermal stressed regions with the value of 1.45 Pa are observed at the corners of lipid core and the plaque/lumen interface. The mathematical model developed provides a tool to analyze the factors affecting heat transfer at the plaque surface. The results may contribute to the understanding of the relationship between plaque temperature and the likelihood of rupture, and also provide a tool to better understand arterial wall temperature measurements obtained with novel catheters. Advisors/Committee Members: Ley, Obdulia (advisor), Annamalai, Kalyan (committee member), Arroyave, Raymundo (committee member), Walton, Jay (committee member).

Subjects/Keywords: Atherosclerotic plaque; Arterial wall temperature; Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kim, T. (2009). Thermal study of vulnerable atherosclerotic plaque. (Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2541

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kim, Taehong. “Thermal study of vulnerable atherosclerotic plaque.” 2009. Thesis, Texas A&M University. Accessed December 14, 2019. http://hdl.handle.net/1969.1/ETD-TAMU-2541.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kim, Taehong. “Thermal study of vulnerable atherosclerotic plaque.” 2009. Web. 14 Dec 2019.

Vancouver:

Kim T. Thermal study of vulnerable atherosclerotic plaque. [Internet] [Thesis]. Texas A&M University; 2009. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2541.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kim T. Thermal study of vulnerable atherosclerotic plaque. [Thesis]. Texas A&M University; 2009. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2541

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Texas A&M University

26. Sawant, Onkar Balkrishna. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.

Degree: 2013, Texas A&M University

URL: http://hdl.handle.net/1969.1/151882

► Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol… (more)

▼ Women who drink alcohol during pregnancy are at high risk of giving birth to children with physical, behavioral or cognitive developmental problems called Fetal Alcohol Spectrum Disorders (FASD). Prenatal alcohol exposure is known to be associated with fetal growth restriction, disturbances in amino acid bioavailability, and alterations in fetal hemodynamics, blood flow and oxidative stress. Alterations in these parameters can persist into adolescence and low birth weight can lead to altered fetal development and programming, which can have lifelong consequences. Glutamine has been associated with fetal nitrogen and carbon metabolism, synthesis of the cellular anti-oxidant glutathione, apoptosis suppression, serving as a precursor for the synthesis of other amino acids, and increases in protein synthesis. Glutamine has been used clinically as a nutrient supplement in low birth weight infants. Therefore, it is hypothesized that repeated third trimester-equivalent maternal alcohol exposure in the sheep model decreases the bioavailability of amino acids, hampers fetal body growth, alters maternal-fetal hemodynamics, hampers uterine blood flow, alters fetal blood flow, increases cerebellar oxidative stress and that maternal L-glutamine supplementation may attenuate these negative developmental effects of prenatal alcohol exposure. Maternal alcohol exposure during the third trimester-equivalent period in the sheep model significantly reduced fetal body weight, height, crown-rump length and thoracic girth, and maternal glutamine supplementation successfully improved these fetal growth parameters in the alcohol+glutamine group. Maternal alcohol exposure during the third trimester-equivalent period resulted in significant reduction in glutamine and glutamine related amino acids bioavailability in maternal and fetal plasma as well as in the fetal amniotic and allantoic fluid. Maternal glutamine supplementation improved the bioavailability and efficacy of amino acids in the maternal and fetal compartment. This study also revealed that maternal alcohol exposure resulted in maternal acidemia, maternal hypercapnea, maternal hypoxemia as well as fetal acidemia and fetal hypercapnea, but not fetal hypoxemia. Maternal alcohol exposure during this period led to an increase in fetal mean arterial pressure, alterations in fetal brain blood flow and fetal cerebellar oxidative stress. Maternal alcohol exposure during the third trimester-equivalent period resulted in a more than 40% reduction in uterine artery blood flow. Maternal glutamine supplementation during the third trimester-equivalent period successfully attenuated the incidences of alcohol-induced maternal hypercapnea, fetal acidemia, alterations in fetal brain blood flow and improved the fetal cerebellar endogenous antioxidant status. Collectively these results signify that maternal glutamine supplementation mitigates negative developmental effects of prenatal alcohol exposure. Advisors/Committee Members: Washburn, Shannon E (advisor), Wu, Guoyao (committee member), Miranda, Rajesh (committee member), Golding, Michael (committee member).

Subjects/Keywords: FASD; Teratology; Glutamine; Alcohol; Blood-flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sawant, O. B. (2013). Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. (Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/151882

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Thesis, Texas A&M University. Accessed December 14, 2019. http://hdl.handle.net/1969.1/151882.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sawant, Onkar Balkrishna. “Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol.” 2013. Web. 14 Dec 2019.

Vancouver:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Internet] [Thesis]. Texas A&M University; 2013. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/1969.1/151882.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sawant OB. Effects of Maternal L-glutamine Supplementation on Fetus to Mitigate Teratogenic Effects of Alcohol. [Thesis]. Texas A&M University; 2013. Available from: http://hdl.handle.net/1969.1/151882

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Nairobi

27. Nabulindo, Wilkister, N. Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya.

Degree: 2016, University of Nairobi

URL: http://hdl.handle.net/11295/99079

► The livestock sector in Kenya contributes about 10% of the Gross Domestic Product (GDP) with the dairy subsector accounting for 4%. Eighty percent of this… (more)

▼ The livestock sector in Kenya contributes about 10% of the Gross Domestic Product (GDP) with the dairy subsector accounting for 4%. Eighty percent of this contribution is from small scale dairy farmers currently challenged by low reproductive efficiency caused by poor estrus detection, delayed determination of unsuccessful artificial insemination (AI) and sub-optimal calving to conception interval. Blood levels of progesterone (P4) are a valid indicator of the reproductive status of an animal. The current study sought to document P4 levels that could be used to determine the estrous phase of the cows to enable prompt remedial action where it was unsuccessful to optimize reproductive efficiency. The P4 levels were determined using the lateral flow immuno assay (LFIA) and also the knowledge, attitude and practices of various stakeholders in the dairy industry on the use of P4 as a reproductive management tool was evaluated. Blood was collected from 46 animals to establish the P4 profiles at the various stages of the reproductive cycle using enzyme linked immunosorbent assay (ELISA). Subsequently, P4 levels analyzed by LFIA and ELISA in blood from 100 dairy cattle were compared for the degree of agreement. Questionnaires were administered to various stakeholders in the dairy industry to determine their knowledge, attitude and practices on use of P4 as a reproductive management tool. Animal Health Practitioners (n=127) and dairy farmers (n=25) were interviewed in the present study. There was limited knowledge amongst dairy cattle industry stakeholders on the LFIA P4 kit and lack of its use in reproductive management of dairy cattle. The P4 profiles of dairy cattle ranged from 0.2-10ng/ml. Pre-pubertal animals and those in the follicular phase of the cycle had P4 levels of 0.2 to 2.8ng/ml. Non-pregnant luteal phase and pregnant animals had higher (p<0.05) P4 levels ranging between 4 to 10ng/ml. LFIA P4 scores ranged from 1 to 2 for pre-pubertal and follicular phase animals. The scores were higher (p<0.05) ranging from 2.5 to 3 for non-pregnant luteal phase and pregnant animals. The semi-quantitative P4 levels as determined by the LFIA were highly correlated (r 0.95; kappa=0.93) with the quantitative ELISA P4 levels of 0-4 ng/ml and 4-10 ng/ml, respectively for low and high P4 concentrations. The breed, body condition and weight did not influence the concentration of P4 levels. Progesterone levels as determined by ELISA were higher (p<0.05) for pregnant than nonpregnant luteal phase animals. Forty two percent of Animal Health Practitioners (AHP) and none of dairy farmers were aware of P4 kits for heat detection whereas 46% of AHP and 4% of dairy farmers were aware of P4 kits for pregnancy diagnosis. Overall, a larger proportion of both the dairy farmers and AHP indicated that the P4 kits would be important in reproductive management and they would use them in reproductive management of dairy cattle. These findings show that LFIA is a simple, rapid, reliable method for determination of P4…

Subjects/Keywords: Blood Progesterone Determination by Lateral Flow Immunoassay

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Nabulindo, Wilkister, N. (2016). Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya. (Thesis). University of Nairobi. Retrieved from http://hdl.handle.net/11295/99079

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Nabulindo, Wilkister, N. “Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya. ” 2016. Thesis, University of Nairobi. Accessed December 14, 2019. http://hdl.handle.net/11295/99079.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Nabulindo, Wilkister, N. “Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya. ” 2016. Web. 14 Dec 2019.

Vancouver:

Nabulindo, Wilkister N. Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya. [Internet] [Thesis]. University of Nairobi; 2016. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/11295/99079.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nabulindo, Wilkister N. Blood Progesterone Determination by Lateral Flow Immunoassay for Assessment of Reproductive Status of Dairy Cattle in Kenya. [Thesis]. University of Nairobi; 2016. Available from: http://hdl.handle.net/11295/99079

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

28. Mubyana, Maswabi Mukela. Some aspects of hemodynamics on blood flow .

Degree: 2012, University of Zambia

URL: http://hdl.handle.net/123456789/1688

Subjects/Keywords: Blood flow.; Hemodynamics.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Mubyana, M. M. (2012). Some aspects of hemodynamics on blood flow . (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/1688

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mubyana, Maswabi Mukela. “Some aspects of hemodynamics on blood flow .” 2012. Thesis, University of Zambia. Accessed December 14, 2019. http://hdl.handle.net/123456789/1688.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mubyana, Maswabi Mukela. “Some aspects of hemodynamics on blood flow .” 2012. Web. 14 Dec 2019.

Vancouver:

Mubyana MM. Some aspects of hemodynamics on blood flow . [Internet] [Thesis]. University of Zambia; 2012. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/123456789/1688.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mubyana MM. Some aspects of hemodynamics on blood flow . [Thesis]. University of Zambia; 2012. Available from: http://hdl.handle.net/123456789/1688

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. 出島, 遼. ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ.

Degree: Nara Institute of Science and Technology / 奈良先端科学技術大学院大学

URL: http://hdl.handle.net/10061/10559

Subjects/Keywords: Blood flow velocity

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

出島, �. (n.d.). ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ. (Thesis). Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Retrieved from http://hdl.handle.net/10061/10559

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

出島, 遼. “ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ.” Thesis, Nara Institute of Science and Technology / 奈良先端科学技術大学院大学. Accessed December 14, 2019. http://hdl.handle.net/10061/10559.

Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

出島, 遼. “ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ.” Web. 14 Dec 2019.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

出島 �. ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ. [Internet] [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; [cited 2019 Dec 14]. Available from: http://hdl.handle.net/10061/10559.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Council of Science Editors:

出島 �. ラット脳微小血管における血流速度自動決定法の研究開発 : Development of an automatic determination method for microvessel blood flow velocity estimation in rat's brain; ラットノウビショウケッカンニオケルケツリュウソクドノジドウケッテイホウノケンキュウカイハツ. [Thesis]. Nara Institute of Science and Technology / 奈良先端科学技術大学院大学; Available from: http://hdl.handle.net/10061/10559

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

Humboldt State University

30. Pace, Jonathan R. Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress.

Degree: MS, Environmental Systems: Mathematical Modeling, 2011, Humboldt State University

URL: http://hdl.handle.net/2148/794

► Atherosclerosis, hardening of the arteries, is a leading cause of death in America. Endothelial cells line the arteries and exhibit different morphology (shape) and different… (more)

Subjects/Keywords: Mathematical modeling; Endothelial cells; Blood flow

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pace, J. R. (2011). Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress. (Masters Thesis). Humboldt State University. Retrieved from http://hdl.handle.net/2148/794

Chicago Manual of Style (16^th Edition):

Pace, Jonathan R. “Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress.” 2011. Masters Thesis, Humboldt State University. Accessed December 14, 2019. http://hdl.handle.net/2148/794.

MLA Handbook (7^th Edition):

Pace, Jonathan R. “Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress.” 2011. Web. 14 Dec 2019.

Vancouver:

Pace JR. Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress. [Internet] [Masters thesis]. Humboldt State University; 2011. [cited 2019 Dec 14]. Available from: http://hdl.handle.net/2148/794.

Council of Science Editors:

Pace JR. Endothelial cells and blood flow: a mathematical model of early mechanical and electrophysiological reponses to shear stress. [Masters Thesis]. Humboldt State University; 2011. Available from: http://hdl.handle.net/2148/794

		in
And / Or
		in
And / Or
		in
And / Or
		in

Open Access Theses and Dissertations