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Oregon State University
1.
Chiang, Kai-sun.
The relationship between biorhythms and injuries in female college gymnastic participants.
Degree: MS, Education, 1985, Oregon State University
URL: http://hdl.handle.net/1957/40975
► Biorhythm theory proponents believe that humans have a 23-day physical cycle, a 28-day emotional cycle, and a 33-day intellectual cycle. According to biorhythm theories a…
(more)
▼ Biorhythm theory proponents believe that humans have
a 23-day physical cycle, a 28-day emotional cycle, and a
33-day intellectual cycle. According to biorhythm theories
a person in the positive portion of any single cycle, the performance potential is enhanced for those tasks related to
that particular rhythm. When each cycle crosses the base
line from positive to negative, or vice versa, that point
represents a critical day in that particular cycle. During
critical days, the performance potential is considered highly
unstable. The theory proposes that incidents of human
error are especially numerous on critical days.
The purpose of this study was to determine if athletic injuries of female college gymnasts become more numerous with respect to critical days of physical, emotional,
and/or intellectual biorhythm cycles. Data were collected
from a sample of fourteen injured female gymnasts of Oregon State University. A total of thirty injuries were recorded
over a period from 1981 to 1984.
Critical days were calculated for each of the injured
individuals in accordance with two definitions of critical
days. Chi-Square with Yates' correction for continuity was
employed to determine statistical significance at the .05
level of confidence.
In each instance the hypothesis testing rejected the
null hypothesis. The number of injuries which occurred
during critical days or negative phases of biorhythm
cycles were not more than the number of injuries which
occurred during non-critical days or positive phases.
Therefore, the biorhythm theories were not supported by
the data of this study.
Advisors/Committee Members: Irvin, Richard F. (advisor), Poling, Peter D. (committee member).
Subjects/Keywords: Biological rhythms
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APA (6th Edition):
Chiang, K. (1985). The relationship between biorhythms and injuries in female college gymnastic participants. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/40975
Chicago Manual of Style (16th Edition):
Chiang, Kai-sun. “The relationship between biorhythms and injuries in female college gymnastic participants.” 1985. Masters Thesis, Oregon State University. Accessed January 27, 2021.
http://hdl.handle.net/1957/40975.
MLA Handbook (7th Edition):
Chiang, Kai-sun. “The relationship between biorhythms and injuries in female college gymnastic participants.” 1985. Web. 27 Jan 2021.
Vancouver:
Chiang K. The relationship between biorhythms and injuries in female college gymnastic participants. [Internet] [Masters thesis]. Oregon State University; 1985. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1957/40975.
Council of Science Editors:
Chiang K. The relationship between biorhythms and injuries in female college gymnastic participants. [Masters Thesis]. Oregon State University; 1985. Available from: http://hdl.handle.net/1957/40975

Oregon State University
2.
Jun, Tae Won.
The relationship between biorhythms and injuries to college football participants.
Degree: MS, Education, 1984, Oregon State University
URL: http://hdl.handle.net/1957/41413
► Purpose: The general problem was to determine the relationship between biorhythms and injuries to college football participants representing Oregon State University. Procedures: The population consisted…
(more)
▼ Purpose: The general problem was to determine the relationship between biorhythms and injuries to college football participants representing Oregon State University. Procedures: The population consisted of one hundred and ninty two football players representing Oregon State University who participated in the intercollegiate football seasons of 1981 and 1982. Injury data and birth data for this study were obtained from Kevin O'Neill Oregon State University Head Athletic Trainer. The injury data were recorded for each year and added for total number of injuries. The method referred to as "biomathematics" as outlined by Thommen was selected as the most appropriate procedure to calculate and chart the biorhythms of the injured football players. To examine the accuracy of Thommen's charting method, the Dialgraf calculator was also used. Analysis of Data: The data were analyzed by means of chi square design. A significant level of .05 for rejection or acceptance of the null hypothesis was selected: Conclusions: From the statistical evaluation of the results, the following conclusions may be made. 1. There is no relationship between the critical days of the biorhythm of individual players and the occurrence of football injuries. 2. There is no relationship between the physical, the emotional and the intellectual
biological rhythms and the occurrence of football injuries. 3. There is no relationship between the combination of physical, emotional and intellectual
biological rhythms and the occurrence of football injuries.
Advisors/Committee Members: Irvin, Richard F. (advisor), Michael, Robert E. (committee member).
Subjects/Keywords: Biological rhythms
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APA (6th Edition):
Jun, T. W. (1984). The relationship between biorhythms and injuries to college football participants. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/41413
Chicago Manual of Style (16th Edition):
Jun, Tae Won. “The relationship between biorhythms and injuries to college football participants.” 1984. Masters Thesis, Oregon State University. Accessed January 27, 2021.
http://hdl.handle.net/1957/41413.
MLA Handbook (7th Edition):
Jun, Tae Won. “The relationship between biorhythms and injuries to college football participants.” 1984. Web. 27 Jan 2021.
Vancouver:
Jun TW. The relationship between biorhythms and injuries to college football participants. [Internet] [Masters thesis]. Oregon State University; 1984. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1957/41413.
Council of Science Editors:
Jun TW. The relationship between biorhythms and injuries to college football participants. [Masters Thesis]. Oregon State University; 1984. Available from: http://hdl.handle.net/1957/41413

Oregon State University
3.
Zimmerman, Richard Orin.
Biorhythms' relation to industrial accidents.
Degree: MS, Health Education, 1978, Oregon State University
URL: http://hdl.handle.net/1957/43146
► The theory of Biorhythms is an up and coming topic. Its founding fathers: Dr, Fliess, Dr. Swoboda, and Dr. Teltsher discovered the 23 day physical…
(more)
▼ The theory of Biorhythms is an up and coming topic.
Its founding fathers: Dr, Fliess, Dr. Swoboda, and
Dr. Teltsher discovered the 23 day physical 28 day sensitivity,
and 33 day Intellectual cycles around the turn of the century.
Today, biorhythms are being looked at and studied
from many different disciplines. Over seventy five studies
on biorhythm have been noted in the review of literature.
There is a great amount of controversy over the
reliability of the biorhythm theory. Some safety professionals
believe in biorhythms, and use them as a tool
to reduce accidents in the workplace.
Two hundred and twenty two accidents from Zidell
Explorations, Inc., a Portland, Oregon based firm, was
used to test the validity of the biorhythm theory. Using
all the accidents for a complete year, an analysis revealed
that the level of significance for all methods of analysis
could not reject any of the nine null hypotheses of the
study. Therefore, the study could not verify the biorhythm
theory. The conclusion stated that even though the theory
was not verified, biorhythms could be used in the workplace
to promote more employee-employer relations.
Recommendations for further study was made. Consisting
of personal information that includes birth place and
exact times of birth along with other recommendations.
Advisors/Committee Members: Lawson, David C. (advisor).
Subjects/Keywords: Biological rhythms
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APA (6th Edition):
Zimmerman, R. O. (1978). Biorhythms' relation to industrial accidents. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/43146
Chicago Manual of Style (16th Edition):
Zimmerman, Richard Orin. “Biorhythms' relation to industrial accidents.” 1978. Masters Thesis, Oregon State University. Accessed January 27, 2021.
http://hdl.handle.net/1957/43146.
MLA Handbook (7th Edition):
Zimmerman, Richard Orin. “Biorhythms' relation to industrial accidents.” 1978. Web. 27 Jan 2021.
Vancouver:
Zimmerman RO. Biorhythms' relation to industrial accidents. [Internet] [Masters thesis]. Oregon State University; 1978. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1957/43146.
Council of Science Editors:
Zimmerman RO. Biorhythms' relation to industrial accidents. [Masters Thesis]. Oregon State University; 1978. Available from: http://hdl.handle.net/1957/43146

Oregon State University
4.
Tweedy, David Graham.
Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell.
Degree: MS, Entomology, 1966, Oregon State University
URL: http://hdl.handle.net/1957/47211
► The purpose of the study was to determine an emergence rhythm, its period, and the developmental stages susceptible to emergence synchronization in the leafcutter bee…
(more)
▼ The purpose of the study was to determine an emergence
rhythm, its period, and the developmental stages susceptible to
emergence synchronization in the leafcutter bee Megachile rotundata
(Fabricius). An attempt was made to determine if an oxygen consumption
rhythm was present in the pupal and adult stages of the
alkali bee Nomia melanderi Cockerell.
A circadian emergence rhythm with a 22 to 24 hour cycle was
determined in Megachile rotundata. Temperature was found to be
an effective emergence synchronizer. A temperature shock of 11 C°
for 12 hours was sufficient to synchronize the emergence of M.
rotundata cultures for at least six days. A temperature perturbation
as low as six hours synchronized emergence in a culture of M.
rotundata but a perturbation of one hour did not saturate the culture
and thus a distinct emergence rhythm failed to develop.
Light intensity up to 14 ft-c. was found to have no effect on the rhythm of emergence.
The phase of the emergence rhythm in M. rotundata is directly
related to the time at which a culture is removed from the cold following
a temperature shock rather than to the time it is placed in the
cold. Cultures subjected to cold periods of 24, 12, and 6 hours displayed
close phase relationship to each other when they were removed
from the cold at the same time.
M. rotundata appears to be susceptible to emergence synchronization
by temperature in the black-thorax and black-abdomen
stages of the pupa and in the adult. It is impossible to draw definite
conclusions from this study as to which stage is susceptible to emergence
synchronization because of the high mortality rate in the insects
used.
Various stages of pupal development were studied in an attempt
to discover an oxygen consumption rhythm in the alkali bee, Nomia
melanderi, but no rhythm was detected.
Advisors/Committee Members: Stephen, W. P. (advisor).
Subjects/Keywords: Biological rhythms
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Tweedy, D. G. (1966). Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/47211
Chicago Manual of Style (16th Edition):
Tweedy, David Graham. “Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell.” 1966. Masters Thesis, Oregon State University. Accessed January 27, 2021.
http://hdl.handle.net/1957/47211.
MLA Handbook (7th Edition):
Tweedy, David Graham. “Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell.” 1966. Web. 27 Jan 2021.
Vancouver:
Tweedy DG. Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell. [Internet] [Masters thesis]. Oregon State University; 1966. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1957/47211.
Council of Science Editors:
Tweedy DG. Circadian rhythms in Megachile rotundata (Fabricius) and Nomia melanderi Cockerell. [Masters Thesis]. Oregon State University; 1966. Available from: http://hdl.handle.net/1957/47211
5.
Cissé, Yasmine-marie Nirina, Cisse.
Multigenerational effects of pre-conception circadian
disruption by light at night.
Degree: PhD, Neuroscience Graduate Studies Program, 2017, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794
► Over the past several billion years, virtually all organisms have been selected to develop endogenous biological rhythms of about 24-hours, or circadian rhythms. Proper synchronization…
(more)
▼ Over the past several billion years, virtually all
organisms have been selected to develop endogenous
biological
rhythms of about 24-hours, or circadian
rhythms. Proper
synchronization of internal circadian
rhythms to the consistent
solar cycle provides adaptive anticipation of daily patterns in the
environment. However, in the past century the world has undergone a
marked increase in nighttime illumination allowing for the
development of “24-hr societies” and night shift work. Night shift
workers provided the initial evidence for the increased risk of
mood disorders, cancer development, and metabolic disorders
associated with chronic exposure to light at night, but similar
risks are beginning to be reported in the general population.
Virtually every individual and organism in the developed world is
exposed to aberrant nighttime lighting. Exposure to dim light at
night (dLAN; 5 lux) disrupts molecular timekeeping mechanisms and
alters rhythmic production of endocrine messengers of circadian
time in nocturnal rodents. Chemical disruption of hormone signaling
or release in a primary organism has the potential to alter
physiology and behavior in offspring and grand-offspring through
persistent changes in the epigenome. However, no studies to date
have investigated the impact of the systemic disruption induced by
dLAN on future generations. In this dissertation, I provide
evidence for the multigenerational effects of dim nighttime light
exposure prior to conception on offspring physiology and
behavior.The transgenerational effects of endocrine disruption are
often secondary to changes in endocrine function. Melatonin and
glucocorticoids act as the humoral signals of circadian time to
peripheral tissues; exposure to dLAN flattens rhythmic production
cortisol and eliminates nightly melatonin. In addition to their
roles in circadian timekeeping, these hormones reciprocally
regulate one another’s receptor expression and have opposing
actions in regulating affective behavior and immunity, systems
altered by exposure to dLAN. Therefore, I first investigated
whether pre-conception dLAN altered expression of melatonin (MT1)
and glucocorticoid (GR) receptors in offspring. The effects of
pre-conception exposure to dLAN on offspring hippocampal and
splenic MT1 and GR expression are described in Chapters 2 and 4,
respectively. The effects of pre-conception dLAN on offspring
hippocampal endocrine receptor expression are considered along with
assessments of offspring depressive-like behavior in Chapter 2.
Increased depressive-like behavior in adult Siberian hamsters
exposed to dLAN are dependent on increases in hippocampal tnf-a,
suggesting interactions of immune and mood regulation. Therefore,
in Chapters 3 and 4 I investigate the effects of pre-conception
dLAN on innate and adaptive immune measures. Offspring febrile,
cytokine, and functional immune responses to an endotoxin challenge
in response to parental dLAN are described in Chapter 3. In Chapter
4, immune phenotyping is extended with reports of T-cell and B-cell
mediated…
Advisors/Committee Members: Nelson, Randy (Advisor).
Subjects/Keywords: Neurosciences; Molecular Biology; Endocrinology; endogenous biological rhythms; circadian rhythms
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Cissé, Yasmine-marie Nirina, C. (2017). Multigenerational effects of pre-conception circadian
disruption by light at night. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794
Chicago Manual of Style (16th Edition):
Cissé, Yasmine-marie Nirina, Cisse. “Multigenerational effects of pre-conception circadian
disruption by light at night.” 2017. Doctoral Dissertation, The Ohio State University. Accessed January 27, 2021.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794.
MLA Handbook (7th Edition):
Cissé, Yasmine-marie Nirina, Cisse. “Multigenerational effects of pre-conception circadian
disruption by light at night.” 2017. Web. 27 Jan 2021.
Vancouver:
Cissé, Yasmine-marie Nirina C. Multigenerational effects of pre-conception circadian
disruption by light at night. [Internet] [Doctoral dissertation]. The Ohio State University; 2017. [cited 2021 Jan 27].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794.
Council of Science Editors:
Cissé, Yasmine-marie Nirina C. Multigenerational effects of pre-conception circadian
disruption by light at night. [Doctoral Dissertation]. The Ohio State University; 2017. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794

University of Alberta
6.
Loewan, Anne.
Biorhythm and intellectual functioning.
Degree: Master of Education in Counselling Psychology, Department of Educational Psychology, 1979, University of Alberta
URL: https://era.library.ualberta.ca/files/n009w449n
Subjects/Keywords: Intellect.; Biological rhythms.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Loewan, A. (1979). Biorhythm and intellectual functioning. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/n009w449n
Chicago Manual of Style (16th Edition):
Loewan, Anne. “Biorhythm and intellectual functioning.” 1979. Masters Thesis, University of Alberta. Accessed January 27, 2021.
https://era.library.ualberta.ca/files/n009w449n.
MLA Handbook (7th Edition):
Loewan, Anne. “Biorhythm and intellectual functioning.” 1979. Web. 27 Jan 2021.
Vancouver:
Loewan A. Biorhythm and intellectual functioning. [Internet] [Masters thesis]. University of Alberta; 1979. [cited 2021 Jan 27].
Available from: https://era.library.ualberta.ca/files/n009w449n.
Council of Science Editors:
Loewan A. Biorhythm and intellectual functioning. [Masters Thesis]. University of Alberta; 1979. Available from: https://era.library.ualberta.ca/files/n009w449n

Univerzitet u Beogradu
7.
Milošević, Vuk D. 1976-.
Analiza vremenskih serija obolevanja od moždanog
udara.
Degree: Medicinski fakultet, 2013, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get
► Medicina - Neurologija / Medicine - Neurology
Dosadašnja istraživanja ukazala su da obolevanje od moždanog udara (MU) nije slucajno rasporeeno u vremenu vec da postoje…
(more)
▼ Medicina - Neurologija / Medicine -
Neurology
Dosadašnja istraživanja ukazala su da obolevanje od
moždanog udara (MU) nije slucajno rasporeeno u vremenu vec da
postoje jasni dnevni, nedeljni i sezonski obrasci. Podaci koji se
koriste za ovu vrstu analiza cesto predstavljaju vremenske serije
(u vremenu ureeni niz podataka) i zahtevaju posebne metode za
analizu vremenskih serija. Znacajan izvor podataka o obolevanju od
moždanog udara predstavljaju izveštaji o osobama lecenim u
stacionarnim uslovima, tzv. hospitalni registri. Ciljevi ovog
istraživanja bili su: provera validnosti podataka u korišcenom
hospitalnom registru, ispitivanje demografskih karakteristika
hospitalizovanih pacijenata, analiza dnevnog i nedeljnog variranja
broja prijema obolelih od razlicitih tipova MU, identifikacija
ARIMA modela mesecnih i kvartalnih vremenskih serija, analiza
sezonskog variranja broja prijema obolelih od razlicitih tipova MU
na osnovu definisanih modela i ispitivanje uticaja meteoroloških
faktora na sezonske varijacije u broju hospitalizovanih pacijenata
obolelih od moždanog udara na osnovu modela funkcije prenosa.
Istraživanje je dizajnirano po tipu nepopulacione deskriptivne
studije. Osnovni izvor podataka bio je elektronski registar
pacijenata Klinike za neurologiju, Klinickog centra u Nišu. Ovim
istraživanjem su obuhvaceni hospitalni prijemi pacijenata koji su
kao završnu dijagnozu imali subarahnoidnu hemoragiju (SAH),
intracerebralnu hemoragiju (ICH), akutni ishemijski moždani udar
(AIMU) ili nespecifikovani tip moždanog udara (NMU). U slucaju
analize dnevnih i nedeljnih varijacija broja prijema uzorak je
stratifikovan prema polu, obrazovanju i starosti. Za analizu
dnevnih i nedeljnih varijacija podaci su grupisani i podeljeni na
cetiri šestocasovna perioda dana, sedam dana u nedelji i na dane
vikenda i radne dane. Korišcen je 2 c test za uporeivanje
registrovanog i ocekivanog broja hospitalizovanih pacijenata.
Izdvojeni su dani u nedelji odnosno periodi dana sa najvecim i
najmanjim brojem hospitalnih prijema. Sezonske varijacije u
obolevanju od moždanog udara su ispitivane metodama za analizu
vremenskih serija. Vremenskim agregiranjem su formirane prekidne
vremenske serije broja hospitalizacija na mesecnom i kvartalanom
nivou, posebno za svaki tip MU. Vremenske serije su modelovane
korišcenjem Box Jenkinsovog metoda izgradnje ARIMA (autoregresioni
integrisani proces pokretnih proseka) modela...
Advisors/Committee Members: Beslać-Bumbaširević, Ljiljana, 1952-.
Subjects/Keywords: stroke; biological rhythms; time series; ARIMA
model
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Milošević, V. D. 1. (2013). Analiza vremenskih serija obolevanja od moždanog
udara. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Milošević, Vuk D 1976-. “Analiza vremenskih serija obolevanja od moždanog
udara.” 2013. Thesis, Univerzitet u Beogradu. Accessed January 27, 2021.
https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Milošević, Vuk D 1976-. “Analiza vremenskih serija obolevanja od moždanog
udara.” 2013. Web. 27 Jan 2021.
Vancouver:
Milošević VD1. Analiza vremenskih serija obolevanja od moždanog
udara. [Internet] [Thesis]. Univerzitet u Beogradu; 2013. [cited 2021 Jan 27].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Milošević VD1. Analiza vremenskih serija obolevanja od moždanog
udara. [Thesis]. Univerzitet u Beogradu; 2013. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong
8.
Lam, Wai-wai, Vivian.
Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea).
Degree: 1980, University of Hong Kong
URL: http://hdl.handle.net/10722/32928
Subjects/Keywords: Bivalvia;
Biological rhythms.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lam, Wai-wai, V. (1980). Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea). (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/32928
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Lam, Wai-wai, Vivian. “Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea).” 1980. Thesis, University of Hong Kong. Accessed January 27, 2021.
http://hdl.handle.net/10722/32928.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Lam, Wai-wai, Vivian. “Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea).” 1980. Web. 27 Jan 2021.
Vancouver:
Lam, Wai-wai V. Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea). [Internet] [Thesis]. University of Hong Kong; 1980. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10722/32928.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Lam, Wai-wai V. Feeding and digestion in
the intertidal 'false' cockle Anomalocardia squamosa (Linnaeus)
(Bivalvia: Veneracea). [Thesis]. University of Hong Kong; 1980. Available from: http://hdl.handle.net/10722/32928
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Simon Fraser University
9.
Duval, Wayne Stuart.
Diel rhythms in the respiration and feeding rates of zooplankton. – .
Degree: 1973, Simon Fraser University
URL: http://summit.sfu.ca/item/3347
Subjects/Keywords: Biological rhythms.; Zooplankton.
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Duval, W. S. (1973). Diel rhythms in the respiration and feeding rates of zooplankton. – . (Thesis). Simon Fraser University. Retrieved from http://summit.sfu.ca/item/3347
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Duval, Wayne Stuart. “Diel rhythms in the respiration and feeding rates of zooplankton. – .” 1973. Thesis, Simon Fraser University. Accessed January 27, 2021.
http://summit.sfu.ca/item/3347.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Duval, Wayne Stuart. “Diel rhythms in the respiration and feeding rates of zooplankton. – .” 1973. Web. 27 Jan 2021.
Vancouver:
Duval WS. Diel rhythms in the respiration and feeding rates of zooplankton. – . [Internet] [Thesis]. Simon Fraser University; 1973. [cited 2021 Jan 27].
Available from: http://summit.sfu.ca/item/3347.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Duval WS. Diel rhythms in the respiration and feeding rates of zooplankton. – . [Thesis]. Simon Fraser University; 1973. Available from: http://summit.sfu.ca/item/3347
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
10.
Allega, Olivia.
Biological Rhythms, Sleep and Cognition in Mood Disorders.
Degree: MSc, 2016, McMaster University
URL: http://hdl.handle.net/11375/20473
► This thesis presents research investigating the relationship between, and methods of, measuring circadian rhythms in mood disorders in a population of currently depressed and euthymic…
(more)
▼ This thesis presents research investigating the relationship between, and methods of, measuring circadian rhythms in mood disorders in a population of currently depressed and euthymic individuals with both depression and bipolar disorder. This was first assessed by comparing group differences in subjective sleep and circadian measures with objective sleep and circadian measures. The objective circadian measures involved actigraphy and melatonin profiling. This analysis showed group differences in subjective sleep and circadian parameters compared to controls, however no robust differences between mood groups. Objective melatonin profiling showed a mild agreement with subjective circadian parameters. Next, we studied the external validity of a subjective rating scale measuring biological rhythm disturbance, the Biological Rhythms Interview for Assessment in Neuropsychiatry (BRIAN), against objective measures of sleep and circadian activity rhythmicity. The BRIAN demonstrated some promising external validity, namely correlations with wake after sleep onset (WASO) and sleep efficiency, as well as melatonin levels in each group. These studies provide evidence of the extent to which a self-report may help in assessing parameters of sleep and circadian rhythms in the clinical setting. In doing so, it is expected that the use of subjective ratings will provide insight into the impact of biological rhythms disturbances and mood disorders. Lastly, we conducted an overview of the preclinical and clinical literature investigating the impact of circadian disturbance on cognitive performance. The results from this literature review yielded patterns of rhythmicity in specific parameters in each of the attention, memory, and executive function domains in humans, whereas attention and memory are more of a primary focus in animal studies. However, we also found that there are significant gaps in the understanding of how disturbances in circadian rhythms may influence cognitive function. This review also highlights the importance of cross-species translational validity from a methodological perspective, in order to generate positive clinical results beginning at the preclinical stage in neuropsychiatric disorders.
Thesis
Master of Science (MSc)
Advisors/Committee Members: Frey, Benicio, Health Sciences.
Subjects/Keywords: biological rhythms; circadian rhythms; major depressive disorder; bipolar disorder; sleep; melatonin; actigraphy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Allega, O. (2016). Biological Rhythms, Sleep and Cognition in Mood Disorders. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/20473
Chicago Manual of Style (16th Edition):
Allega, Olivia. “Biological Rhythms, Sleep and Cognition in Mood Disorders.” 2016. Masters Thesis, McMaster University. Accessed January 27, 2021.
http://hdl.handle.net/11375/20473.
MLA Handbook (7th Edition):
Allega, Olivia. “Biological Rhythms, Sleep and Cognition in Mood Disorders.” 2016. Web. 27 Jan 2021.
Vancouver:
Allega O. Biological Rhythms, Sleep and Cognition in Mood Disorders. [Internet] [Masters thesis]. McMaster University; 2016. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11375/20473.
Council of Science Editors:
Allega O. Biological Rhythms, Sleep and Cognition in Mood Disorders. [Masters Thesis]. McMaster University; 2016. Available from: http://hdl.handle.net/11375/20473

University of Edinburgh
11.
Prior, Kimberley Faith.
The evolutionary ecology of circadian rhythms in malaria parasites.
Degree: PhD, 2018, University of Edinburgh
URL: http://hdl.handle.net/1842/29562
► Biological rhythms are thought to have evolved to enable organisms to organise their activities according to the Earth’s predictable cycles, but quantifying the fitness advantages…
(more)
▼ Biological rhythms are thought to have evolved to enable organisms to organise their activities according to the Earth’s predictable cycles, but quantifying the fitness advantages of rhythms is challenging and data revealing their costs and benefits are scarce. More difficult still is explaining why parasites that exclusively live within the bodies of other organisms have biological rhythms. Rhythms exist in the development and traits of parasites, in host immune responses, and in disease susceptibility. This raises the possibility that timing matters for how hosts and parasites interact and, consequently, for the severity and transmission of diseases. Despite their obvious importance in other fields, circadian rhythms are a neglected aspect of ecology and evolutionary biology. The ambitions of this thesis are to integrate chronobiology, parasitology and evolutionary theory with mathematical models to obtain a greater understanding about how and suggest why malaria parasites have rhythms as well as the effect of infection on host rhythms. First, I identify how malaria parasites lose their developmental rhythms in culture, when they lack any potential time cues from the host. Next, I characterise parasite rhythms inside the mammalian host in terms of synchrony and timing and demonstrate there is genotype by environment interactions for characteristics of parasite rhythms. Then, I investigate the effect that parasite infection has on host rhythms and show there is variation between parasite genotypes in their effect on host locomotor activity and body temperature rhythms during infections. Finally, I explore which host rhythms may be driving parasite synchrony and timing and demonstrate the importance of peripheral host rhythms for the timing of malaria parasite developmental rhythms. The data presented here provides novel and important information on the role of rhythms during disease and opens up a new arena for studying host-parasite coevolution.
Subjects/Keywords: 571.7; biological rhythms; malaria parasites; host-parasite interactions; host rhythms; host-parasite coevolution
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Prior, K. F. (2018). The evolutionary ecology of circadian rhythms in malaria parasites. (Doctoral Dissertation). University of Edinburgh. Retrieved from http://hdl.handle.net/1842/29562
Chicago Manual of Style (16th Edition):
Prior, Kimberley Faith. “The evolutionary ecology of circadian rhythms in malaria parasites.” 2018. Doctoral Dissertation, University of Edinburgh. Accessed January 27, 2021.
http://hdl.handle.net/1842/29562.
MLA Handbook (7th Edition):
Prior, Kimberley Faith. “The evolutionary ecology of circadian rhythms in malaria parasites.” 2018. Web. 27 Jan 2021.
Vancouver:
Prior KF. The evolutionary ecology of circadian rhythms in malaria parasites. [Internet] [Doctoral dissertation]. University of Edinburgh; 2018. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1842/29562.
Council of Science Editors:
Prior KF. The evolutionary ecology of circadian rhythms in malaria parasites. [Doctoral Dissertation]. University of Edinburgh; 2018. Available from: http://hdl.handle.net/1842/29562

Michigan State University
12.
Langel, Jennifer Lou.
Masking and its neural substrates in day- and night-active mammals.
Degree: 2016, Michigan State University
URL: http://etd.lib.msu.edu/islandora/object/etd:3990
► Thesis Ph. D. Michigan State University. Neuroscience - Doctor of Philosophy 2016.
Light can directly and acutely alter arousal states, a process known as “masking”.…
(more)
▼ Thesis Ph. D. Michigan State University. Neuroscience - Doctor of Philosophy 2016.
Light can directly and acutely alter arousal states, a process known as “masking”. Masking effects of light are quite different in diurnal and nocturnal animals with light increasing arousal and activity in the former and suppressing in the latter. Few studies have examined chronotype differences in masking or the neural substrates contributing to this process. However, in nocturnal mice, masking responses are mediated through a subset of retinal ganglion cells that are intrinsically photosensitive (termed ipRGCs) due to their expression of the melanopsin protein. The goal of the studies in this dissertation was to first characterize masking responses in day- and night-active animals and then to evaluate the possibility that differences in ipRGC projections or the circuitry within their targets might contribute to species differences in masking.First, I compared behavioral and brain responses to light across individuals within a species (the Nile grass rat, Arvicanthis niloticus). In this diurnal species some individuals become night-active when given access to a running wheel, while others do not. I found that masking responses to light and darkness in these animals were dependent upon the chronotype of the individual. Additionally, the responsiveness of neurons within two brain regions, the intergeniculate leaflet (IGL) and olivary pretectal area (OPT), was associated with the behavioral response of the animal to light.Next, I compared behavioral responses to light and darkness across species, the diurnal grass rat and the nocturnal Norway rat (Rattus norvegicus: Long Evans (LE) strain). Overall, light suppressed general activity in LE rats, while darkness increased it, a pattern very different from that seen previously in grass rats, in which light stimulates activity, but darkness has no effect (Shuboni et al., 2012). I also found that light induced sleep and resting behavior in LE rats and suppressed it in grass rats and that these effects lasted for at least a full hour.To determine whether differences in the projections of ipRGCs may account for species differences in masking, I characterized the melanopsin system of the grass rat and compared it to that previously described in nocturnal rodents. I found that the grass rat retina contained the same basic subtypes of melanopsin cells and that the majority of these cells (87.7%) contained the neuropeptide, pituitary adenylate cyclase-activating polypeptide (PACAP), while 97.4% of PACAP cells contained melanopsin. Since, within the retina, PACAP is found almost exclusively in ipRGCs, I then examined the distribution of PACAP-labeled fibers originating in the retina to characterize ipRGCs projections to the brain. I found that although these were similar to those of nocturnal species, some differences existed in their density in the dorsal and ventral lateral geniculate nucleus (dLGN and vLGN) and in the rostrocaudal extent of the OPT.Finally, to determine whether differences…
Advisors/Committee Members: Smale, Laura, Sisk, Cheryl L, Yan, Lily, Li, Weiming.
Subjects/Keywords: Light – Physiological effect; Biological rhythms; Circadian rhythms; Retinal ganglion cells; Neurosciences; Behavioral sciences
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Langel, J. L. (2016). Masking and its neural substrates in day- and night-active mammals. (Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:3990
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Langel, Jennifer Lou. “Masking and its neural substrates in day- and night-active mammals.” 2016. Thesis, Michigan State University. Accessed January 27, 2021.
http://etd.lib.msu.edu/islandora/object/etd:3990.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Langel, Jennifer Lou. “Masking and its neural substrates in day- and night-active mammals.” 2016. Web. 27 Jan 2021.
Vancouver:
Langel JL. Masking and its neural substrates in day- and night-active mammals. [Internet] [Thesis]. Michigan State University; 2016. [cited 2021 Jan 27].
Available from: http://etd.lib.msu.edu/islandora/object/etd:3990.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Langel JL. Masking and its neural substrates in day- and night-active mammals. [Thesis]. Michigan State University; 2016. Available from: http://etd.lib.msu.edu/islandora/object/etd:3990
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Ryerson University
13.
Atlin, Taryn, M.
An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:.
Degree: 2014, Ryerson University
URL: https://digital.library.ryerson.ca/islandora/object/RULA%3A2614
► Insomnia had generally been conceptualized as a nighttime disorder, while the daytime experience of insomnia has been largely ignored. However, there are several lines of…
(more)
▼ Insomnia had generally been conceptualized as a nighttime disorder, while the daytime
experience of insomnia has been largely ignored. However, there are several lines of research suggesting daytime experiences as well as daytime behaviours are equally important. For example, daily behavioural routines commonly referred to as social
rhythms (e.g., exercise, attendance of school or work, recreation, engagement in social activities) have been identified as potential zeitgebers (i.e., time cues that help to regulate the
biological clock). Previous research has shown that regulating behavioural zeitgebers may have promising benefits for sleep. As such, this study examined the daytime activities in a clinical insomnia population and a good sleeper comparison
group. Participants (N = 69) prospectively monitored their sleep and daily activities for a two-week period, while wearing a wrist actiwatch. Those with insomnia appear to engage in activities characterized by significantly less regularity than good sleepers. However, those with insomnia were found to engage in similar levels of daily activities compared to good sleepers. Findings from this study highlight the relative importance of daytime activities on this supposed nighttime process. Accordingly, future research would benefit from testing treatment components that focus on regulating daytime activities, which would likely improve treatment outcomes.
Advisors/Committee Members: Ryerson University (Degree grantor).
Subjects/Keywords: Insomnia; Insomnia – -; Sleep disorders; Sleep disorders – -; Sleep – Research; Sleep – Research – -; Biological rhythms; Biological rhythms – -; Time – Social aspects; Time – Social aspects – -
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Atlin, Taryn, M. (2014). An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:. (Thesis). Ryerson University. Retrieved from https://digital.library.ryerson.ca/islandora/object/RULA%3A2614
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Atlin, Taryn, M. “An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:.” 2014. Thesis, Ryerson University. Accessed January 27, 2021.
https://digital.library.ryerson.ca/islandora/object/RULA%3A2614.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Atlin, Taryn, M. “An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:.” 2014. Web. 27 Jan 2021.
Vancouver:
Atlin, Taryn M. An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:. [Internet] [Thesis]. Ryerson University; 2014. [cited 2021 Jan 27].
Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A2614.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Atlin, Taryn M. An examination of social rhythms in a clinical insomnia population and good sleeper comparison group:. [Thesis]. Ryerson University; 2014. Available from: https://digital.library.ryerson.ca/islandora/object/RULA%3A2614
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
14.
Martins, Cássia Borges Lima Bulhões.
Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio.
Degree: Mestrado, Fisiologia Geral, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-13032008-144458/
;
► Determinamos a presença de RNA mensageiro de melanopsina em células embrionárias ZEM-2S por PCR, o que foi confirmado por sequenciamento. Os experimentos de PCR para…
(more)
▼ Determinamos a presença de RNA mensageiro de melanopsina em células embrionárias ZEM-2S por PCR, o que foi confirmado por sequenciamento. Os experimentos de PCR para receptores de melatonina em cDNA de células ZEM-2S sugeriram a presença do subtipo MT2 em células ZEM-2S. Não foram identificadas bandas correspondentes ao peso esperado para MT1 ou Mel 1C. A identidade do receptor MT2 em ZEM-2S foi confirmada por sequenciamento. Determinamos ainda que, em células embrionárias ZEM-2S, os seis genes Cry conhecidos para Danio rerio estão expressos. Quando as células ZEM-2S foram expostas ao regime de claro e escuro (12C:12E), a expressão de melanopsina apresentou dois picos: no início da fase de claro ZT3, e no início da fase de escuro ZT12. Estes picos foram mantidos quando as células foram submetidas a escuro constante e, curiosamente, em todos os ZTs houve aumento significativo de expressão quando comparados aos ZTs equivalentes das células submetidas a ciclo claro:escuro. Melanopsina não apresentou ritmicidade de expressão em células ZEM-2S em nenhuma das condições. No entanto, há uma tendência a ritmicidade em células mantidas em 12C:12E, que desaparece em escuro constante. O pulso de melatonina aparentemente estimulou a expressão na fase de escuro subjetivo, mas sem significância estatística. O RNAm de Clock não exibiu ritmo em células ZEM-2S mantidas em condições de 12C:12E, escuro constante, ou em escuro constante recebendo pulso de melatonina. Há no entanto visível tendência a aumento de expressão na escotofase e durante o escuro subjetivo, a qual é abolida pelo pulso de melatonina. O RNAm de Per 1 e Cry 1b apresentou marcada ritmicidade em células submetidas a fotoperíodo 12C:12E. Vê-se aumento significativo 3 horas antes do início da fase de luz (ZT21), e acentuado declínio na fase de escuro. Em escuro constante, a ritmicidade de Per1 e Cry1b foi grandemente atenuada, mas persistiu. O pulso de melatonina foi ineficaz em recuperar a amplitude da ritmicidade observada em 12C:12E, e ainda mais, aboliu a ritmicidade para ambos os genes. Após um pulso de melatonina, os genes Clock, Per1 e Cry1b de células ZEM- 2S perderam a expressão rítmica que ainda persistia em escuro constante. É provável que melatonina, semelhantemente ao observado em outras preparações, iniba a fosforilação de CREB nas células ZEM-2S, assim reduzindo a ativação dos promotores dos genes do relógio. De qualquer forma, poderíamos interpretar que a melatonina traz os genes de relógio para um mesmo patamar, dessa forma reajustando o ritmo, independente da fase. Nosso estudo traz contribuições importantes para o conhecimento da fisiologia de relógios periféricos e abre novas perspectivas para futuras investigações sobre mecanismos subjacentes a ritmos em células isoladas e sua regulação por hormônios e luz.
The presence of melanopsin mRNA in ZEM-2S embryonic cells was determined through PCR, followed by sequencing. PCR experiments for melatonin receptors with ZEM-2S cell cDNA suggested the presence of the MT2 subtype. Bands corresponding to…
Advisors/Committee Members: Castrucci, Ana Maria de Lauro.
Subjects/Keywords: Biological rhythms; Células embrionárias; Embryonic cells; Melatonin; Melatonina; Ritmos biológicos
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Martins, C. B. L. B. (2007). Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/41/41135/tde-13032008-144458/ ;
Chicago Manual of Style (16th Edition):
Martins, Cássia Borges Lima Bulhões. “Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio.” 2007. Masters Thesis, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/41/41135/tde-13032008-144458/ ;.
MLA Handbook (7th Edition):
Martins, Cássia Borges Lima Bulhões. “Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio.” 2007. Web. 27 Jan 2021.
Vancouver:
Martins CBLB. Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio. [Internet] [Masters thesis]. University of São Paulo; 2007. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-13032008-144458/ ;.
Council of Science Editors:
Martins CBLB. Expressão gênica temporal de Melanopsina (Opn4), Clock, Cry e Per e sua regulação por melatonina em células de Danio rerio. [Masters Thesis]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-13032008-144458/ ;

Columbia University
15.
Kahl, Lisa Juliane.
Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa.
Degree: 2020, Columbia University
URL: https://doi.org/10.7916/d8-zr0r-2428
► Earth’s organisms are exposed to day-night cycles. These periodic changes in environmental factors, such as temperature and light exposure, trigger regulatory processes that coordinate physiological…
(more)
▼ Earth’s organisms are exposed to day-night cycles. These periodic changes in environmental factors, such as temperature and light exposure, trigger regulatory processes that coordinate physiological adaptations in organisms. Circadian organisms, i.e., most eukaryotes and some phototrophic bacteria, undergo autonomous 24-hour biological rhythms that are synchronized to day-night cycles via sensing light cues. However, the extent to which non-phototrophic bacteria tune their physiology to diurnal cycles and exhibit rhythmic behavior has been underexplored. For my thesis work, I investigated how the chemotrophic bacterium Pseudomonas aeruginosa responds to light and temperature signals. This metabolically versatile bacterium regulates its physiology through a vast array of environmental sensing mechanisms and has evolved multiple strategies to cope with redox imbalances. This thesis seeks to address how P. aeruginosa coordinates its metabolic and redox-balancing programs in response to light and temperature changes that occur in its environmental niche.
In Chapter 1, I will present background information on relevant concepts such as biological rhythms and photosensory mechanisms and discuss how these principles are connected to physiological adaptations and metabolic plasticity in both phototrophic and non-phototrophic organisms, with a specific focus on chemotrophic bacteria. In Chapter 2, I will demonstrate that P. aeruginosa biofilm development is attenuated by light and that this process is regulated by the integration of light and redox signals. My work presented in Chapter 3 will provide evidence that the transcriptomic and metabolic landscape of P. aeruginosa is vastly reorganized in response to light/dark cycles. In the Chapter 4, I will explore how this reprogramming is manifested through activity by the respiratory machinery and I will demonstrate that P. aeruginosa undergoes intrinsic respiratory oscillations.
As an opportunistic pathogen, P. aeruginosa will experience circadian-controlled changes during infection of a (circadian) host through host immune activity as well as exposure to cyclic environmental factors like light and temperature. I will discuss how environmental sensing is relevant for P. aeruginosa’s adaptation to its host-associated lifestyle. In conclusion, the research presented in this thesis establishes that P. aeruginosa exhibits an intricate physiological response to environmental signals, particularly light and temperature. This thesis contributes to a growing body of work that underscores how bacteria have evolved intricate mechanisms to integrate information about their environmental habitat, including host-associated conditions.
Subjects/Keywords: Biology; Microbiology; Metabolism; Biological rhythms; Photobiology; Bacteria – Physiology; Respiration
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kahl, L. J. (2020). Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa. (Doctoral Dissertation). Columbia University. Retrieved from https://doi.org/10.7916/d8-zr0r-2428
Chicago Manual of Style (16th Edition):
Kahl, Lisa Juliane. “Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa.” 2020. Doctoral Dissertation, Columbia University. Accessed January 27, 2021.
https://doi.org/10.7916/d8-zr0r-2428.
MLA Handbook (7th Edition):
Kahl, Lisa Juliane. “Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa.” 2020. Web. 27 Jan 2021.
Vancouver:
Kahl LJ. Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa. [Internet] [Doctoral dissertation]. Columbia University; 2020. [cited 2021 Jan 27].
Available from: https://doi.org/10.7916/d8-zr0r-2428.
Council of Science Editors:
Kahl LJ. Light and Temperature Cues Elicit Metabolic Reprogramming in the Non-phototrophic Bacterium Pseudomonas aeruginosa. [Doctoral Dissertation]. Columbia University; 2020. Available from: https://doi.org/10.7916/d8-zr0r-2428

McMaster University
16.
Slyepchenko, Anastasiya.
Biological Rhythms in Mood and Anxiety.
Degree: PhD, 2020, McMaster University
URL: http://hdl.handle.net/11375/25407
► Introduction: In Major Depressive (MDD) and Bipolar Disorders (BD), there are well-documented changes in sleep and biological rhythms. However, how sleep and biological rhythm disruptions…
(more)
▼ Introduction:
In Major Depressive (MDD) and Bipolar Disorders (BD), there are well-documented changes in sleep and biological rhythms. However, how sleep and biological rhythm disruptions impact functioning and quality of life (QOL) in these populations, and how these disruptions affect perinatal mood and anxiety remains little-known. In this thesis, we aimed to compare sleep and biological rhythms in individuals with and without mood disorders, and to investigate whether these measures can account for worsened functional impairment and QOL in these populations. We investigated whether clinical variables combined with sleep and biological rhythms during pregnancy can be used to predict depressive and anxiety symptom severity postpartum. Finally, we investigated longitudinal changes in sleep, and biological rhythms over the perinatal period.
Results:
Subjective and objective sleep and biological rhythm disruptions, and light exposure differences are wide-spread in MDD and BD. Regression analyses showed that subjective and objective sleep and biological rhythm disruptions can explain 43% of variance in QOL scores, and 52% of variance in functional impairment in MDD, BD and healthy controls.
Clinical and demographic variables, objective and subjective sleep and biological rhythm measures collected during pregnancy accounted for 50% of postpartum depression and 49% of postpartum anxiety symptom severity variance, in regression analyses. Numerous sleep and biological rhythm changes occurred across multiple domains from pregnancy to postpartum.
Conclusion:
Results suggest that sleep and biological rhythm disruptions occur across many domains in mood disorders, including sleep, light exposure, daily activity rhythms and melatonin. These disruptions are associated with worse QOL and functioning in BD, MDD and healthy controls. Biological rhythms and sleep changes across the perinatal period can be used to predict severity of postpartum depressive and anxiety symptoms. This work highlights the importance of sleep and biological rhythms as intervention targets across different outcomes, and across different mood diagnoses.
Thesis
Doctor of Philosophy (PhD)
Sleep and biological rhythms are often disrupted in individuals with depression and bipolar disorder. In this thesis, we aimed to compare sleep and biological rhythms in individuals with depression or bipolar disorder, against individuals without these disorders. We investigated whether sleep and biological rhythms contribute to functioning and quality of life in these individuals. As sleep and biological rhythms are disrupted in pregnancy and following childbirth, we assessed whether sleep and biological rhythms during pregnancy can be used to predict postpartum depression and anxiety severity. Finally, we investigated changes in sleep, biological rhythms and light exposure from pregnancy to postpartum. Results indicate that disruptions in sleep, biological rhythms, and changes in light exposure are widespread in mood disorders. These disruptions are linked…
Advisors/Committee Members: Frey, Benicio N, Neuroscience.
Subjects/Keywords: biological rhythms; mood disorders; actigraphy; postpartum depression; postpartum anxiety
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APA (6th Edition):
Slyepchenko, A. (2020). Biological Rhythms in Mood and Anxiety. (Doctoral Dissertation). McMaster University. Retrieved from http://hdl.handle.net/11375/25407
Chicago Manual of Style (16th Edition):
Slyepchenko, Anastasiya. “Biological Rhythms in Mood and Anxiety.” 2020. Doctoral Dissertation, McMaster University. Accessed January 27, 2021.
http://hdl.handle.net/11375/25407.
MLA Handbook (7th Edition):
Slyepchenko, Anastasiya. “Biological Rhythms in Mood and Anxiety.” 2020. Web. 27 Jan 2021.
Vancouver:
Slyepchenko A. Biological Rhythms in Mood and Anxiety. [Internet] [Doctoral dissertation]. McMaster University; 2020. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11375/25407.
Council of Science Editors:
Slyepchenko A. Biological Rhythms in Mood and Anxiety. [Doctoral Dissertation]. McMaster University; 2020. Available from: http://hdl.handle.net/11375/25407
17.
Brand, Karl.
Transcripts from the Circadian Clock: Telling Time and Season.
Degree: 2011, Erasmus University Medical Center
URL: http://hdl.handle.net/1765/23697
► textabstractWe all know it when we wake mere moments before an alarm clock is scheduled to wake us: our body clock made the alarm clock…
(more)
▼ textabstractWe all know it when we wake mere moments before an alarm clock is scheduled to wake us: our
body clock made the alarm clock redundant. This phenomenon is driven by an endogenous
timer known as the biological, or circadian clock. Each revolution of the Earth about its own
axis produces periods of light and dark which define what we all experience as a ‘da
Subjects/Keywords: Circadian rhythms; biological clock
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Brand, K. (2011). Transcripts from the Circadian Clock: Telling Time and Season. (Doctoral Dissertation). Erasmus University Medical Center. Retrieved from http://hdl.handle.net/1765/23697
Chicago Manual of Style (16th Edition):
Brand, Karl. “Transcripts from the Circadian Clock: Telling Time and Season.” 2011. Doctoral Dissertation, Erasmus University Medical Center. Accessed January 27, 2021.
http://hdl.handle.net/1765/23697.
MLA Handbook (7th Edition):
Brand, Karl. “Transcripts from the Circadian Clock: Telling Time and Season.” 2011. Web. 27 Jan 2021.
Vancouver:
Brand K. Transcripts from the Circadian Clock: Telling Time and Season. [Internet] [Doctoral dissertation]. Erasmus University Medical Center; 2011. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/1765/23697.
Council of Science Editors:
Brand K. Transcripts from the Circadian Clock: Telling Time and Season. [Doctoral Dissertation]. Erasmus University Medical Center; 2011. Available from: http://hdl.handle.net/1765/23697

Montana State University
18.
Arnott, David Phillip.
Forced unilateral nostril breathing affects lateralized cognitive functions.
Degree: MS, College of Letters & Science, 1985, Montana State University
URL: https://scholarworks.montana.edu/xmlui/handle/1/5988
Subjects/Keywords: Biological rhythms.; Cerebral dominance.; Respiration.
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Export
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APA (6th Edition):
Arnott, D. P. (1985). Forced unilateral nostril breathing affects lateralized cognitive functions. (Masters Thesis). Montana State University. Retrieved from https://scholarworks.montana.edu/xmlui/handle/1/5988
Chicago Manual of Style (16th Edition):
Arnott, David Phillip. “Forced unilateral nostril breathing affects lateralized cognitive functions.” 1985. Masters Thesis, Montana State University. Accessed January 27, 2021.
https://scholarworks.montana.edu/xmlui/handle/1/5988.
MLA Handbook (7th Edition):
Arnott, David Phillip. “Forced unilateral nostril breathing affects lateralized cognitive functions.” 1985. Web. 27 Jan 2021.
Vancouver:
Arnott DP. Forced unilateral nostril breathing affects lateralized cognitive functions. [Internet] [Masters thesis]. Montana State University; 1985. [cited 2021 Jan 27].
Available from: https://scholarworks.montana.edu/xmlui/handle/1/5988.
Council of Science Editors:
Arnott DP. Forced unilateral nostril breathing affects lateralized cognitive functions. [Masters Thesis]. Montana State University; 1985. Available from: https://scholarworks.montana.edu/xmlui/handle/1/5988

McMaster University
19.
El Dahr, Yola.
Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder.
Degree: MSc, 2020, McMaster University
URL: http://hdl.handle.net/11375/25899
► Introduction: Sleep and biological rhythms have not been investigated in women with comorbid Bipolar and Premenstrual Dysphoric Disorder in the context of the menstrual cycle.…
(more)
▼ Introduction: Sleep and biological rhythms have not been investigated in women with comorbid Bipolar and Premenstrual Dysphoric Disorder in the context of the menstrual cycle. We explored whether menstrual cycle phase causes increased disturbances in sleep, biological rhythms and mood symptoms. Additionally, we explored whether these women have worse illness outcome than women diagnosed with either Bipolar or Premenstrual Dysphoric Disorder, and healthy women.
Methods: In this post-hoc analysis, participants were split into four groups: those with a Bipolar and comorbid Premenstrual Dysphoric Disorder diagnosis (n = 17, BDPMDD), those with a Bipolar Disorder diagnosis (n = 16, BD), those with a Premenstrual Dysphoric Disorder diagnosis (n = 19, PMDD), and women with no history of psychiatric diagnosis (n = 25, HC). The primary outcome variable was biological rhythm disruption as measured by the Biological Rhythms Interview and Assessment in Neuropsychiatry (BRIAN). The secondary outcome variables were depressive symptoms (Montgomery-Asberg Depression Scale, MADRS; Hamilton Depression Rating Scale, HAMD), manic symptoms (Young Mania Rating Scale, YMRS), and sleep quality (Pittsburgh Sleep Quality Index, PSQI). All variables were collected at both mid-follicular and late-luteal stages of the menstrual cycle.
Results: The BDPMDD group did not have significantly higher disruptions in biological rhythms than the BD or PMDD groups at the luteal phase; however, there were significant disruptions and mood symptoms in comparison to the HC group, especially at the follicular stage, which point to markedly higher disruptions in these areas that seem to persist beyond the symptomatic luteal phase.
Conclusion and Future Directions: Women diagnosed with a BD and PMDD comorbidity experience a higher illness burden then women diagnosed with either BD or PMDD. A relatively small sample size, not excluding for participants who were taking medications that affect sleep and relying solely on subjective measures of biological rhythms may explain some of the null results. Future studies should employ objective measures of sleep such as actigraphy to complement subjective measures like the BRIAN, as well as recruit a larger sample of participants. More importantly, more studies surrounding this topic must be done in order to create a robust body of evidence that can be used to compare results across studies and identify specific biological rhythms domains that can be targets for treatment.
Thesis
Master of Science (MSc)
Sleep disruptions are common in women diagnosed with Bipolar Disorder and in those diagnosed with Premenstrual Dysphoric Disorder. Illness burden has been shown to be greater in women diagnosed with a comorbidity of the above disorders in terms of clinical variables such as number of comorbidities, episode relapse, rapid cycling and mixed mood states. This thesis aims to investigate whether women diagnosed with Bipolar and comorbid Premenstrual Dysphoric Disorder have greater biological rhythms disruptions…
Advisors/Committee Members: Frey, Benicio, Neuroscience.
Subjects/Keywords: Bipolar Disorder; Premenstrual Dysphoric Disorder; Biological Rhythms; Menstrual Cycle
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
El Dahr, Y. (2020). Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/25899
Chicago Manual of Style (16th Edition):
El Dahr, Yola. “Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder.” 2020. Masters Thesis, McMaster University. Accessed January 27, 2021.
http://hdl.handle.net/11375/25899.
MLA Handbook (7th Edition):
El Dahr, Yola. “Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder.” 2020. Web. 27 Jan 2021.
Vancouver:
El Dahr Y. Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder. [Internet] [Masters thesis]. McMaster University; 2020. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11375/25899.
Council of Science Editors:
El Dahr Y. Investigating Biological Rhythms Disruptions Across the Menstrual Cycle in Women with Comorbid Bipolar Disorder and Premenstrual Dysphoric Disorder. [Masters Thesis]. McMaster University; 2020. Available from: http://hdl.handle.net/11375/25899

University of Melbourne
20.
David, Michael Costan.
The relationship between the intellectual biorhythm cycle and academic performance.
Degree: 1985, University of Melbourne
URL: http://hdl.handle.net/11343/113876
► The problem presented in, this study was the investigation of the existence of a 33-day intellectual cycle. The study was designed to answer two questions.…
(more)
▼ The problem presented in, this study was the investigation of the existence of a 33-day intellectual cycle. The study was designed to answer two questions.
First, does evidence exist to indicate a 33-day intellectual cycle in which an observable difference occurs in academic performance on the Progressive Achievement Test in Mathematics as administered on ascending critical, descending critical, lour point and peak point days? Secondly, does evidence exist to indicate a relationship between a 33-day intellectual cycle and a sex of subject difference which is reflected in the measurement of academic performance as measured by the Progressive Achievement Test in Mathematics?
The data were then subjected to two methods of analysis. First, analysis of variance was carried out on Test 2A and Test 2B respectively. Secondly, analysis of covariance was carried out. The analysed data consisted of 104 pairs of test scores.- These scores were obtained from 104. Year 7 and 8 students from Mildura High School who completed two parallel forms of the Progressive Achievement Test in Mathematics.
Hypotheses pertaining to the intellectual biorhythm cycle, sex of subject, and their two-way interaction were formulated and each was tested at the 0.05 level of significance. Six hypotheses were examined, Analysis of variance was employed to test the first three null hypotheses, and analysis of covariance was employed to test the three other hypotheses.
In summary, five of the six null hypotheses were accepted at the 0.05 level. No evidence was found in this study to support the theory that a relationship existed between the intellectual biorhythm cycle and academic performance. Similarly, no evidence was found to support the theory that a relationship exists between the two-way interaction of sex of subject and biorhythm phase with respect to academic performance. In contrast to these results, a significant relationship was observed between the sex of subject and academic performance as measured by the Progressive Achievement Test in Mathematics. This relationship was then. examined over two testing sessions by analysis of covariance. No significant response by sex to change in biorhythm phase were found to exist.
On the basis of this study, several recommendations for future research. on biorhythm theory were given. These recommendations considered the collection of data and research design. Finally, it was pointed out that the validity of the biorhythm theory is open to debate and that future studies be scientifically rigorous.
Subjects/Keywords: Biological rhythms; Intelligence tests
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MLA ·
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APA (6th Edition):
David, M. C. (1985). The relationship between the intellectual biorhythm cycle and academic performance. (Masters Thesis). University of Melbourne. Retrieved from http://hdl.handle.net/11343/113876
Chicago Manual of Style (16th Edition):
David, Michael Costan. “The relationship between the intellectual biorhythm cycle and academic performance.” 1985. Masters Thesis, University of Melbourne. Accessed January 27, 2021.
http://hdl.handle.net/11343/113876.
MLA Handbook (7th Edition):
David, Michael Costan. “The relationship between the intellectual biorhythm cycle and academic performance.” 1985. Web. 27 Jan 2021.
Vancouver:
David MC. The relationship between the intellectual biorhythm cycle and academic performance. [Internet] [Masters thesis]. University of Melbourne; 1985. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/11343/113876.
Council of Science Editors:
David MC. The relationship between the intellectual biorhythm cycle and academic performance. [Masters Thesis]. University of Melbourne; 1985. Available from: http://hdl.handle.net/11343/113876

Massey University
21.
Baker, Tania.
Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
.
Degree: 1999, Massey University
URL: http://hdl.handle.net/10179/12316
► The present study examined the effects of light intensity and duration on mental performance at night. A number of investigations have found light levels as…
(more)
▼ The present study examined the effects of light intensity and duration on mental performance at night. A number of investigations have found light levels as low as 500 lux can have a significant impact on cognition, but there have been few, if any, systematic experiments that have investigated the potential trade-off between the intensity of the light and its duration. Light levels of 100 (normal room lighting), 300, 600 and 1,000 lux were paired with one of two different light exposure times: 15 and 60 minutes. Sixteen volunteers completed tests of critical thinking, simple maths, letter cancellation, recall, and recognition between 2300 and 0100 hours once a week for four consecutive weeks. Body temperature and subjective sleepiness levels were also recorded. The results showed that, in general, light intensities, irrespective of duration, of 300 and 600 lux had a positive effect on critical thinking and recognition memory. In contrast to some previous findings, there was little or no effect on sleepiness levels, core body temperature, recall, letter cancellation or the simple maths task. Surprisingly, the 1,000 lux light level had no effect on any of the tasks. It was concluded that changes in the intensity of broad-spectrum light can affect night-time cognitive performance, but that the intensity of the light cannot be traded for duration. However, further investigation of the manner in which light intensity is varied, either by distance from the light or by varying the brightness of the light source, is required before firm conclusions can be drawn.
Subjects/Keywords: Light – Physiological effect;
Biological rhythms
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Baker, T. (1999). Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
. (Thesis). Massey University. Retrieved from http://hdl.handle.net/10179/12316
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Baker, Tania. “Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
.” 1999. Thesis, Massey University. Accessed January 27, 2021.
http://hdl.handle.net/10179/12316.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Baker, Tania. “Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
.” 1999. Web. 27 Jan 2021.
Vancouver:
Baker T. Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
. [Internet] [Thesis]. Massey University; 1999. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10179/12316.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Baker T. Broad spectrum light and night-time mental performance : effects of intensity and duration : a thesis completed in partial fulfilment of the requirements for the degree of Master of Arts
. [Thesis]. Massey University; 1999. Available from: http://hdl.handle.net/10179/12316
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University
22.
Schrader, Jessica Anne.
Plasticity in the circadian system : changing rhythms in reproducing female rodents.
Degree: PhD, Zoology and Ecology, Evolutionary Biology, and Behavior, 2009, Michigan State University
URL: http://etd.lib.msu.edu/islandora/object/etd:17049
Subjects/Keywords: Circadian rhythms; Biological rhythms; Rodents – Reproduction; Suprachiasmatic nucleus
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schrader, J. A. (2009). Plasticity in the circadian system : changing rhythms in reproducing female rodents. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:17049
Chicago Manual of Style (16th Edition):
Schrader, Jessica Anne. “Plasticity in the circadian system : changing rhythms in reproducing female rodents.” 2009. Doctoral Dissertation, Michigan State University. Accessed January 27, 2021.
http://etd.lib.msu.edu/islandora/object/etd:17049.
MLA Handbook (7th Edition):
Schrader, Jessica Anne. “Plasticity in the circadian system : changing rhythms in reproducing female rodents.” 2009. Web. 27 Jan 2021.
Vancouver:
Schrader JA. Plasticity in the circadian system : changing rhythms in reproducing female rodents. [Internet] [Doctoral dissertation]. Michigan State University; 2009. [cited 2021 Jan 27].
Available from: http://etd.lib.msu.edu/islandora/object/etd:17049.
Council of Science Editors:
Schrader JA. Plasticity in the circadian system : changing rhythms in reproducing female rodents. [Doctoral Dissertation]. Michigan State University; 2009. Available from: http://etd.lib.msu.edu/islandora/object/etd:17049
23.
Bueno, Clarissa.
Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos.
Degree: PhD, Fisiologia Humana, 2011, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23012012-160249/
;
► Fatores ambientais podem modificar o desenvolvimento dos ritmos biológicos em neonatos, como já demonstrado em ratos. Neste contexto insere-se o estudo de recém-nascidos pré-termo mantidos…
(more)
▼ Fatores ambientais podem modificar o desenvolvimento dos ritmos biológicos em neonatos, como já demonstrado em ratos. Neste contexto insere-se o estudo de recém-nascidos pré-termo mantidos em unidades de cuidado neonatal. Descrevemos neste trabalho a evolução da ritmicidade no ciclo vigília/sono, atividade/repouso, temperatura do punho e alimentação na fase neonatal. Paralelamente, caracterizamos o desenvolvimento dos ritmos biológicos em ratos mantidos sob luz constante durante a lactação e a atuação da melatonina e do exercício físico nessa evolução. Em um estudo longitudinal utilizando actímetros e termistores com memória, identificamos precocemente ritmo circadiano na temperatura do punho, enquanto na atividade motora há predomínio de ritmos ultradianos, bem como no ciclo vigília/sono e no comportamento alimentar, padrão este que se modifica logo após a alta hospitalar. Em ratos sob o paradigma de luz constante, oferecemos melatonina e uma roda durante a lactação e após o desmame, encontrando modificações na emergência do ritmo circadiano em ambos os grupos.
Environmental factors can change the development of biological rhythms in neonates, as has already been demonstrated in rats. In this context is the study of preterm newborns maintained in neonatal care units. We describe in the present work the evolution of rhythmicity in sleep/wake cycle, activity/rest, wrist temperature and feeding behavior along the neonatal phase. Simultaneously, we characterize the development of biological rhythms in rats maintained under constant light during lactation and the action of melatonin and physical exercise in this evolution. Through a longitudinal study using actimeters and thermistors with memory we identified precociously a circadian rhythm in wrist temperature, while in motor activity we found a dominant ultradian rhythm, as well as, in sleep/wake cycle and feeding behavior, with changes in this pattern just after hospital discharge. In rats reared under constant light, we offered melatonin and a wheel during lactation and after weaning, finding differences in the emergency of the circadian rhythm for both groups.
Advisors/Committee Members: Barreto, Luiz Silveira Menna.
Subjects/Keywords: Animal biological rhythms; Biological rhythms in humans; Circadian rhythm; Newborn; Ontogenia; Ontogeny; Recém-nascido; Ritmo circadiano; Ritmo ultradiano; Ritmos biológicos animal; Ritmos biológicos em humanos; Ultradian rhythm
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Bueno, C. (2011). Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23012012-160249/ ;
Chicago Manual of Style (16th Edition):
Bueno, Clarissa. “Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos.” 2011. Doctoral Dissertation, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23012012-160249/ ;.
MLA Handbook (7th Edition):
Bueno, Clarissa. “Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos.” 2011. Web. 27 Jan 2021.
Vancouver:
Bueno C. Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23012012-160249/ ;.
Council of Science Editors:
Bueno C. Estudo da ontogênese dos ritmos biológicos em neonatos humanos e ratos. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-23012012-160249/ ;

Universidade do Rio Grande do Sul
24.
Moraes, Cláudia Ávila.
Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas.
Degree: 2011, Universidade do Rio Grande do Sul
URL: http://hdl.handle.net/10183/30977
► Distúrbios cronobiológicos na Depressão podem ser explicados pela perda do poder ou estabilidade circadiana observados pela diminuição da amplitude dos ritmos e o maior número…
(more)
▼ Distúrbios cronobiológicos na Depressão podem ser explicados pela perda do poder ou estabilidade circadiana observados pela diminuição da amplitude dos ritmos e o maior número de frequências ou ritmos ultradianos (ritmos com períodos menores que 20 horas). A perda da sincronização entre os ritmos pode ser decodificada pelos sistemas fisiológicos como um estressor, capaz de iniciar, acelerar, perpetuar e exacerbar sintomas neuropsiquiátricos, visto que há uma integração de redes rítmicas estruturais e funcionais Métodos Foram avaliadas 10 pacientes com Depressão Maior em seu primeiro episódio, ainda sem uso de medicação antidepressiva, 10 pacientes com Depressão Recorrente em tratamento e 10 controles saudáveis, todas do sexo feminino. O diagnóstico de Transtorno Depressivo foi realizado através do SCID e CID 10. Os sintomas depressivos foram avaliados através das escalas Beck, MADRS e Hamilton. Os ritmos biológicos atividade-repouso e temperatura cutânea foram medidos com o actímetro Act 1.1 durante 7 dias. Também se avaliou a exposição à luz de cada sujeito. Foi utilizado o teste de Kolmogorov-Smirnov para confirmar se as varáveis tinham distribuição normal. Parâmetros de ritmos e diferenças sócio-demográficas foram analisados através de ANOVA/Tukey. O coeficiente de correlação de Rank-Spearman foi utilizado para analisar a correlação entre temperatura e atividade. Para avaliar diferenças nos escores das escalas entre os dois grupos de deprimidas foi utilizado teste t de Student para amostras independentes. Para variáveis categóricas, foi utilizado o teste qui-quadrado. Resultados O grupo de deprmidas apresentou amplitude de temperatura mais alta e amplitude de atividade mais baixa do que as controles saudáveis. Também, a correlação entre temperatura e atividade nas deprimidas apresentou maior diferença durante o dia e durante a noite do que nas controles saudáveis. Não houve diferença significativa entre deprimidas no seu primeiro episódio sem medicação e pacientes com Depressão Recorrente com medicação no que se refere à amplitude dos ritmos de temperatura e atividade-repouso. Houve acoplamento dos ritmos estudados nos três grupos Discussão Em nosso estudo, as pacientes depressivas apresentaram maior amplitude de temperatura que indivíduos saudáveis, apesar do uso de antidepressivos; as controles saudáveis demonstraram menos diferença entre os ritmos durante o dia e à noite, o que talvez foi causado pela maior atividade em pessoas saudáveis mascarando o ritmo de temperatura. Outra explicação para o aumento da amplitude circadiana em pacientes depressivas é o aumento do arrastamento pelos zeitgebers externos, provavelmente para a manutenção dos mais robustos zeitgebers -social e biológico - que são essenciais para a vida.
Changes of circadian rhythms in Depression may be explained by the loss of power or stability circadian observed by decreasing the amplitude of the rhythms and the higher number of frequencies or ultradian rhythms (rhythms with periods less than 20h). The lack of synchronization between the…
Advisors/Committee Members: Hidalgo, Maria Paz Loayza.
Subjects/Keywords: Depression; Disciplina de cronobiologia; Depressão; Biological rhythms; Chronobiology; Skin temperature; Activity-rest
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moraes, C. . (2011). Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/30977
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Moraes, Cláudia Ávila. “Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas.” 2011. Thesis, Universidade do Rio Grande do Sul. Accessed January 27, 2021.
http://hdl.handle.net/10183/30977.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Moraes, Cláudia Ávila. “Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas.” 2011. Web. 27 Jan 2021.
Vancouver:
Moraes C. Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2011. [cited 2021 Jan 27].
Available from: http://hdl.handle.net/10183/30977.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Moraes C. Avaliação do acoplamento entre os ritmos atividade-repouso e temperatura cutânea em uma amostra de pacientes deprimidas. [Thesis]. Universidade do Rio Grande do Sul; 2011. Available from: http://hdl.handle.net/10183/30977
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
Santos, Eduardo Henrique Rosa.
Atrito temporal em adolescentes escolares.
Degree: PhD, Fisiologia Humana, 2010, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-25032010-143903/
;
► Uma das características dos adolescentes é a fase atrasada dos ritmos biológicos circadianos. Esse atraso na expressão da ritmicidade circadiana pode gerar um atrito entre…
(more)
▼ Uma das características dos adolescentes é a fase atrasada dos ritmos biológicos circadianos. Esse atraso na expressão da ritmicidade circadiana pode gerar um atrito entre o tempo biológico e o tempo social (horário escolar). Assim, analisamos a expressão do atrito temporal entre o tempo biológico e o tempo social em adolescentes escolares. Todos os adolescentes atrasaram os horários do inicio e do final do sono na comparação entre os dias letivos e não letivos. Os adolescentes atrasam a acrofase da temperatura periférica, e a MFS na comparação entre os dias letivos e não letivos. Foi observada uma diminuição significativa para os vespertinos, na ritmicidade circadiana da temperatura na transição dos dias letivos para os dias não letivos. Dessa forma, o deslocamento da acrofase da temperatura e o deslocamento da MFS podem ser a expressão do atrito temporal. Esse cronicidade do atrito pode trazer conseqüências negativas para o bem estar dos adolescentes.
And one of the adolescents characteristics is the latest phase of circadian biological rhythms, compared with children and adults. This delay in the expression of circadian rhythmicity may generate friction between biological time and social time. Thus we analyzed the temporal friction between biological time and social time in scholar adolescents. All adolescents delay the time of beginning and the end of sleep in school days compared to non-school days. All adolescents had a delay in the peripheral temperature acrophase, and the MFS in the comparison between school days and non-school days. Therefore we understand the friction time between the biological and the social through changes in the CVS patterns, shift of peripheral temperature acrophase, and displacement of the MFS, in the transition from school days to non-school days. This chronicity of friction can have negative consequences for the well being of the adolescents.
Advisors/Committee Members: Barreto, Luiz Silveira Menna.
Subjects/Keywords: Adolescentes; Adolescents; Biological rhythms; Chronotypes; Cronotipos; Ritmos biológicos; Sistema de temporização; Timing system
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Santos, E. H. R. (2010). Atrito temporal em adolescentes escolares. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/42/42137/tde-25032010-143903/ ;
Chicago Manual of Style (16th Edition):
Santos, Eduardo Henrique Rosa. “Atrito temporal em adolescentes escolares.” 2010. Doctoral Dissertation, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/42/42137/tde-25032010-143903/ ;.
MLA Handbook (7th Edition):
Santos, Eduardo Henrique Rosa. “Atrito temporal em adolescentes escolares.” 2010. Web. 27 Jan 2021.
Vancouver:
Santos EHR. Atrito temporal em adolescentes escolares. [Internet] [Doctoral dissertation]. University of São Paulo; 2010. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-25032010-143903/ ;.
Council of Science Editors:
Santos EHR. Atrito temporal em adolescentes escolares. [Doctoral Dissertation]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-25032010-143903/ ;
26.
Lapa, Daniela Wey Camilo.
Ritmos biológicos em índios Guarani adultos.
Degree: PhD, Neurociências e Comportamento, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/47/47135/tde-29052008-143531/
;
► Comunidades que vivem em regiões sem energia elétrica apresentam suas atividades sincronizadas pelo ciclo dia/noite e por compromissos sociais podendo haver uma diferença sazonal no…
(more)
▼ Comunidades que vivem em regiões sem energia elétrica apresentam suas atividades sincronizadas pelo ciclo dia/noite e por compromissos sociais podendo haver uma diferença sazonal no comportamento. No ambiente urbano a energia elétrica cria a possibilidade de nos organizarmos temporalmente de acordo com os nossos interesses. Este comportamento tem sido apontado como uma das causas para a ausência de sazonalidade nos ritmos biológicos humanos. Este estudo fenomenológico naturalístico em índios Guarani que viviam em casas sem energia elétrica nos permitiu refletir sobre a presença de sazonalidade nos ritmos biológicos. O ritmo de temperatura do punho em 21 índios e o ciclo de atividade/repouso em 16 índios foram comparados entre o inverno e verão. O perfil temporal da temperatura não se alterou nas duas épocas, mas houve diferença nos valores de amplitude e MESOR que pode ser explicada pela variação sazonal do padrão de dissipação de calor através da pele. Não houve diferença entre o inverno e verão para os valores de acrofase, e os índios mais novos apresentaram horários de acrofase da temperatura mais tardios que os índios mais velhos. Do inverno para o verão observamos um atraso nos horários de repouso sem alteração significativa na duração. Não verificamos diferença nos horários e na duração do repouso entre os dias de semana e fins de semana. O padrão de atividade/repouso não apresentou relação com a duração/alocação da noite no inverno e verão e houve uma correlação negativa com os valores de temperatura do punho. Os índios adultos da Aldeia Boa Vista apresentam ritmos biológicos com características típicas de uma comunidade de transição. As atividades na aldeia são sincronizadas pelas diferentes relações sociais que se estabelecem em cada época do ano.
Communities living in areas without electricity present biological rhythms synchronized by the day/night cycle and social schedules; it seems possible to detect seasonal differences in their behaviour. In urban areas electricity allow us to organize our activities according to our interests. This behaviour has been pointed as a cause for the absence of seasonality in human biological rhythms. The present naturalistic phenomenological study of Guarani indians that living in no electricity houses allowed us to think about the presence of seasonality in biological rhythms. Wrist temperature and activity/rest rhythms of 21 indians were compared between winter and summer. The temperature profile did not change, but a seasonal difference was found for amplitude and MESOR values which may be related to metabolic-behavioral processes involved in thermoregulation. In summer the vasodilation is intense and the heat dissipation is maximum (with low variability), the opposite tends to occur in winter. We did not find seasonality in acrophase values between subjects, and we also found the same correlation described for urban populations: a phase advance of body temperature in the elderly. From winter to summer the onsets/offset of rest were delayed, with no change in rest…
Advisors/Committee Members: Barreto, Luiz Silveira Menna.
Subjects/Keywords: biological rhythms; body temperature; Guarani (indians); índios Guarani; ritmos biológicos; sincronização; syncronization; temperatura do corpo
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lapa, D. W. C. (2007). Ritmos biológicos em índios Guarani adultos. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/47/47135/tde-29052008-143531/ ;
Chicago Manual of Style (16th Edition):
Lapa, Daniela Wey Camilo. “Ritmos biológicos em índios Guarani adultos.” 2007. Doctoral Dissertation, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/47/47135/tde-29052008-143531/ ;.
MLA Handbook (7th Edition):
Lapa, Daniela Wey Camilo. “Ritmos biológicos em índios Guarani adultos.” 2007. Web. 27 Jan 2021.
Vancouver:
Lapa DWC. Ritmos biológicos em índios Guarani adultos. [Internet] [Doctoral dissertation]. University of São Paulo; 2007. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/47/47135/tde-29052008-143531/ ;.
Council of Science Editors:
Lapa DWC. Ritmos biológicos em índios Guarani adultos. [Doctoral Dissertation]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/47/47135/tde-29052008-143531/ ;
27.
Farhat, Fernanda Pizão.
Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio.
Degree: Mestrado, Fisiologia Geral, 2007, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-22032007-105627/
;
► Relógios biológicos são marcapassos endógenos presentes tanto em eucariotos quanto em procariotos. Relógios diferentes possuem períodos distintos, e aqueles que se aproximam de 24h de…
(more)
▼ Relógios biológicos são marcapassos endógenos presentes tanto em eucariotos quanto em procariotos. Relógios diferentes possuem períodos distintos, e aqueles que se aproximam de 24h de oscilação são chamados circadianos. Em mamíferos, o primeiro relógio circadiano identificado situa-se no núcleo supraquiasmático, localizado no hipotálamo. O funcionamento do relógio circadiano envolve mecanismos de retroalimentação positiva e negativa, em geral tendo início com a ativação dos genes Per e Cry por CLOCK e BMAL1. Atualmente sabe-se que os relógios estão presentes em áreas do cérebro fora do núcleo supraquiasmático e em muitos tecidos periféricos. Em Drosophila e Danio rerio, os osciladores periféricos podem ser sincronizados diretamente por luz, enquanto em mamíferos o reinício de fase dos mesmos parece ser controlado por sinais regulados pelo marcapasso do núcleo supraquiasmático. Uma nova opsina, denominada melanopsina, foi recentemente descoberta na retina de todos os vertebrados estudados, em uma subpopulação de células ganglionares intrinsecamente fotossensíveis. Ela é responsável pela captura de luz e envio dessa informação para o núcleo supraquiasmático. A endotelina (ET) é um peptídeo vasoconstritor composto por 21 resíduos de aminoácidos. Existem três isoformas endógenas de ETs, designadas ET-1, ET-2 e ET-3. Três tipos de receptores para endotelinas já foram clonados, sendo eles designados ETA, ETB e ETC. Todos pertencem à família dos receptores acoplados à proteína G. Órgãos, tecidos e células de Danio rerio constituem um excelente modelo para o estudo dos genes de relógio e de ritmos in vitro. Em células embrionárias ZEM 2S deste teleósteo, constatamos a presença de melanopsina, do receptor ETA para endotelina, e dos seis genes Cry através de PCR. A presença de melanopsina também foi confirmada por imunocitoquímica. Foram realizadas curvas de crescimento em células ZEM 2S previamente mantidas por cinco dias em regime de 14C:10E (luz acesa às 9:00h). No 6º. dia, as células foram transferidas para as seguintes condições: escuro constante; 14C:10E; 10C:14E e luz constante. Houve inibição da proliferação celular por luz. O padrão de expressão temporal dos genes Per1, Cry1b, Clock e da melanopsina foi estudado, assim como sua modulação por ET-1. Células ZEM 2S foram mantidas em fotoperíodo 12C:12E (luz acesa às 9:00h) durante cinco dias, após o que foram tratadas com ET-1 nas concentrações 10-11M, 10-10M, 10-9M e 10-8M, durante 24h. O RNA extraído a cada 3h foi submetido a RT-PCR para posterior análise por PCR quantitativo. RNA ribossômico 18S foi utilizado como normalizador do experimento. Melanopsina não apresentou ritmicidade de expressão em fotoperíodo 12C:12E. ET-1 exerceu efeito bifásico, aumentando a expressão nas menores concentrações de hormônio utilizadas e diminuindo nas maiores. Na concentração 10-10M, ET-1 aparentemente estabeleceu uma oscilação ao longo das 24 horas, com crescente expressão na fase de escuro, atingindo um pico em ZT21 e decrescente durante o período de luz, com o mínimo em ZTs 6 e…
Advisors/Committee Members: Castrucci, Ana Maria de Lauro.
Subjects/Keywords: Danio rerio; Danio rerio; Biological rhythms; Células embrionárias; Embryonic cells; Endotelina; Endothelin; Ritmos biológicos
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Farhat, F. P. (2007). Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/41/41135/tde-22032007-105627/ ;
Chicago Manual of Style (16th Edition):
Farhat, Fernanda Pizão. “Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio.” 2007. Masters Thesis, University of São Paulo. Accessed January 27, 2021.
http://www.teses.usp.br/teses/disponiveis/41/41135/tde-22032007-105627/ ;.
MLA Handbook (7th Edition):
Farhat, Fernanda Pizão. “Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio.” 2007. Web. 27 Jan 2021.
Vancouver:
Farhat FP. Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio. [Internet] [Masters thesis]. University of São Paulo; 2007. [cited 2021 Jan 27].
Available from: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-22032007-105627/ ;.
Council of Science Editors:
Farhat FP. Modulação dos genes de relógio Per1, Cry1b, Clock e da melanopsina por endotelina-1 em células embrionárias de Danio rerio. [Masters Thesis]. University of São Paulo; 2007. Available from: http://www.teses.usp.br/teses/disponiveis/41/41135/tde-22032007-105627/ ;
28.
Pasquier, Florane.
Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity.
Degree: Docteur es, Sciences et techniques des activités physiques et sportives, 2020, Normandie
URL: http://www.theses.fr/2020NORMC201
► L’objectif de ce travail de thèse était de tester si la stimulation vestibulaire peut influencer les rythmes biologiques circadiens chez l’Homme. Pour répondre à cet…
(more)
▼ L’objectif de ce travail de thèse était de tester si la stimulation vestibulaire peut influencer les rythmes biologiques circadiens chez l’Homme. Pour répondre à cet objectif, nous avons évalué les effets de deux techniques de stimulation vestibulaire (fauteuil rotatoire et Stimulation Vestibulaire Galvanique/SVG) sur le rythme de l’activité motrice de sujets jeunes sains. Ce projet a également évalué la tolérabilité des protocoles appliqués. La proximité de la technique de SVG avec la stimulation transcrânienne à courant direct (tDCS) utilisée dans les troubles de l’humeur ainsi que les liens entre les troubles des rythmes biologiques et de l’humeur nous ont conduits à évaluer les effets de la stimulation vestibulaire sur le niveau d’anxiété.Une première étude a permis de démontrer que la stimulation induite par un fauteuil rotatoire en fin de journée provoque une diminution du niveau d’activité motrice, ainsi qu’une avance de phase du rythme de l’activité motrice deux jours après la stimulation. Une seconde étude a montré que la SVG appliquée en milieu de journée n’a pas d’effets significatifs sur le rythme de l’activité motrice et la transition entre les états de veille et de sommeil. Enfin, une troisième étude a permis de montrer que la SVG diminue le niveau d’anxiété et que cet effet dépend des paramètres de stimulation appliqués (durée). La technique de SVG est bien tolérée par les participants contrairement à la stimulation sur fauteuil rotatoire qui provoque une augmentation des symptômes de mal des transports.Ces résultats confirment que la stimulation vestibulaire peut être utilisée pour moduler les rythmes biologiques et l’humeur chez l’Homme. Cependant, les effets observés dépendent des paramètres de stimulation appliqués (technique de stimulation, moment de la journée). Ces résultats encouragent la poursuite des investigations concernant l’utilisation de la stimulation vestibulaire comme synchroniseur des rythmes biologiques et la SVG comme outil potentiel de réhabilitation des rythmes biologiques et de l’humeur.
The main objective of this thesis was to test if the vestibular stimulation can impact the circadian biological rhythms in human. We have evaluated the effects of two vestibular stimulation methods (rotatory chair, Galvanic Vestibular Stimulation/GVS) on the motor activity rhythm of young healthy adults. This project also evaluated tolerability of the stimulation protocols. The similarities between GVS and transcranial Direct Current Stimulation (tDCS) used in the treatment of depression, and the links between biological rhythms disorders and mood disorders, have led us to assess the effects of vestibular stimulation on the anxiety level.Effects of vestibular stimulation induced by a rotatory chair at the end of the afternoon has been tested in the first study. We observed a decrease in motor activity level after the vestibular stimulation, and a phase advance effect two days after the stimulation. The second study demonstrated no significant effects of the GVS applied in the middle of the…
Advisors/Committee Members: Quarck, Gäelle (thesis director), Denise, Pierre (thesis director).
Subjects/Keywords: Système vestibulaire; Stimulations vestibulaires; Vestibular system; Vestibular stimulation; Circadian biological rhythms; Mood; Anxiety
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pasquier, F. (2020). Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity. (Doctoral Dissertation). Normandie. Retrieved from http://www.theses.fr/2020NORMC201
Chicago Manual of Style (16th Edition):
Pasquier, Florane. “Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity.” 2020. Doctoral Dissertation, Normandie. Accessed January 27, 2021.
http://www.theses.fr/2020NORMC201.
MLA Handbook (7th Edition):
Pasquier, Florane. “Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity.” 2020. Web. 27 Jan 2021.
Vancouver:
Pasquier F. Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity. [Internet] [Doctoral dissertation]. Normandie; 2020. [cited 2021 Jan 27].
Available from: http://www.theses.fr/2020NORMC201.
Council of Science Editors:
Pasquier F. Etude de l'implication de la fonction vestibulaire dans la rythmicité biologique chez l'Homme : Implication of the vestibular function in human biological rhythmicity. [Doctoral Dissertation]. Normandie; 2020. Available from: http://www.theses.fr/2020NORMC201
29.
Milošević Vuk.
Time series analysis of stroke onset.
Degree: PhD, Medicine, 2012, University of Belgrade
URL: http://dx.doi.org/10.2298/BG20120919MILOSEVIC
;
http://eteze.bg.ac.rs/application/showtheses?thesesId=201
;
https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get
;
http://vbs.rs/scripts/cobiss?command=SEARCH&base=99999&select=ID=42661391
► Available studies have shown that stroke onset is not accidentally distributed in time, but rather that there are clear daily, weekly and seasonal patterns. Data…
(more)
▼ Available studies have shown that stroke onset is not accidentally
distributed in time, but rather that there are clear daily, weekly and
seasonal patterns. Data used for this type of analysis often take the form of
time series (a sequence of measurements ordered in time) and they require
specific methods of time series analysis. A relevant source of data on stroke
onset may be found in institutional reports on in-patients, socalled hospital
registers. The goals of the present research were: checking the validity of
data used in the hospital register, studying the demographic characteristics
of hospitalized patients, analysis of daily and weekly variation in the
number of admissions of patients suffering from various types of stroke,
identification of ARIMA models of monthly and quarterly time series, analysis
of seasonal variation in the number of admissions based on defined models and
studying the influence of meteorological factors on seasonal variations in
the number of hospitalized stroke-affected patients, based on the transfer
function models. The research was designed as a non-population descriptive
study. The principal data source was the electronic patient register of the
Clinic for Neurology, Clinical Center, Niš. The present research encompassed
hospital admissions of patients whose final diagnosis was subarachnoid
hemorrhage (SAH), intracerebral hemorrhage (ICH), acute ischemic stroke (IS),
or unspecified stroke type (US). In the analysis of daily and weekly
variations, the sample was stratified by sex, education, and age. In this
analysis, data were grouped and classified into four six-hour periods in the
day, seven days in the week, and weekends and workdays. The χ2 test was used
for comparing the registered and expected numbers of hospitalized patients.
Days in the week and periods of the day with the highest and lowest numbers
of hospital admissions were separated. Seasonal variations in stroke onset
were tested by time series analysis methods. Time aggregation was used to
form interrupted time series of monthly and quarterly admission numbers,
separately for each stroke type. Time series were modeled using the Box
Jenkins ARIMA (autoregressive integrated moving average) model. The seasonal
nature of a time series was proved by constructing an appropriate seasonal
ARIMA model. In testing the influence of meteorological parameters we used
the transfer function model also known as the multivariate ARIMA model. In
the period 1997-2010 13,420 hospital admissions of patients with a stroke
diagnosis were registered at the Clinic for Neurology, Clinical Center, Niš.
Of these, 51% were men and 49% were women. During hospitalization, 4,087
deaths were registered (30.5%). By analyzing daily variations of stroke
onset, and also of SAH, ICH, IS, and US, we found that the fewest admissions
were registered in the interval 24:00- 05:59h, while the most were allocated
in the interval 12:00-17:59h. We also identified a clear weekly pattern of
the number of admissions, where the…
Subjects/Keywords: stroke; biological rhythms; time series; ARIMA model; moždani udar; biološki ritmovi; vremenske serije; ARIMA model
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Vuk, M. (2012). Time series analysis of stroke onset. (Doctoral Dissertation). University of Belgrade. Retrieved from http://dx.doi.org/10.2298/BG20120919MILOSEVIC ; http://eteze.bg.ac.rs/application/showtheses?thesesId=201 ; https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get ; http://vbs.rs/scripts/cobiss?command=SEARCH&base=99999&select=ID=42661391
Chicago Manual of Style (16th Edition):
Vuk, Milošević. “Time series analysis of stroke onset.” 2012. Doctoral Dissertation, University of Belgrade. Accessed January 27, 2021.
http://dx.doi.org/10.2298/BG20120919MILOSEVIC ; http://eteze.bg.ac.rs/application/showtheses?thesesId=201 ; https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get ; http://vbs.rs/scripts/cobiss?command=SEARCH&base=99999&select=ID=42661391.
MLA Handbook (7th Edition):
Vuk, Milošević. “Time series analysis of stroke onset.” 2012. Web. 27 Jan 2021.
Vancouver:
Vuk M. Time series analysis of stroke onset. [Internet] [Doctoral dissertation]. University of Belgrade; 2012. [cited 2021 Jan 27].
Available from: http://dx.doi.org/10.2298/BG20120919MILOSEVIC ; http://eteze.bg.ac.rs/application/showtheses?thesesId=201 ; https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get ; http://vbs.rs/scripts/cobiss?command=SEARCH&base=99999&select=ID=42661391.
Council of Science Editors:
Vuk M. Time series analysis of stroke onset. [Doctoral Dissertation]. University of Belgrade; 2012. Available from: http://dx.doi.org/10.2298/BG20120919MILOSEVIC ; http://eteze.bg.ac.rs/application/showtheses?thesesId=201 ; https://fedorabg.bg.ac.rs/fedora/get/o:5451/bdef:Content/get ; http://vbs.rs/scripts/cobiss?command=SEARCH&base=99999&select=ID=42661391

University of Manchester
30.
Al-Nuaimi, Yusur Mamoon.
A systems biology approach to the human hair cycle.
Degree: PhD, 2011, University of Manchester
URL: https://www.research.manchester.ac.uk/portal/en/theses/a-systems-biology-approach-to-the-human-hair-cycle(a576aff0-5fbe-4db6-9e13-8211f07e2883).html
;
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549039
► The hair cycle represents a dynamic process during which a complex mini- organ, the hair follicle, rhythmically regresses and regenerates. The control mechanism that governs…
(more)
▼ The hair cycle represents a dynamic process during which a complex mini- organ, the hair follicle, rhythmically regresses and regenerates. The control mechanism that governs the hair cycle ('hair cycle clock') is thought to be an autonomous oscillator system, however, its exact nature is not known. This thesis aims to understand the human hair cycle as a systems biology problem using theoretical and experimental techniques in three distinct study approaches. Using mathematical modelling, a simple two-compartment model of the human hair cycle was developed. The model concentrates on the growth control of matrix keratinocytes, a key cell population responsible for hair growth, and bi-directional communication between these cells and the inductive fibroblasts of the dermal papilla. A bistable switch and feedback inhibition produces key characteristics of human hair cycle dynamics. This study represents the first mathematically formulated theory of the 'hair cycle clock'.A second chronobiological approach was adopted to explore the molecular control of the human hair follicle by a peripheral clock mechanism. The hypothesis was tested that selected circadian clock genes regulate the human hair cycle, namely the clinically crucial follicle transformation from organ growth (anagen) to organ regression (catagen). This revealed that intra- follicular expression of core clock and clock-controlled genes display a circadian rhythm and is hair cycle-dependent. Knock-down of Period1 and Clock promotes anagen maintenance, hair matrix keratinocyte proliferation and stimulates hair follicle pigmentation. This provides the first evidence that peripheral Period1 and Clock gene activity is a component of the human 'hair cycle clock' mechanism. Lastly, an unbiased gene expression profiling approach was adopted to establish important genes and signalling pathways that regulate the human hair cycle. This revealed that similar genes and pathways previously shown to control the murine hair cycle in vivo, such as Sgk3, Msx2 and the BMP pathway, are also differentially regulated during the anagen-catagen transformation of human hair follicles. In summary, by using a three-pronged systems biology approach, the thesis has shed new light on the control of human hair follicle cycling and has generated clinically relevant information: a) The hair cycle model may predict how hair cycle modulatory agents alter human hair growth. b) Period1 and Clock are new therapeutic targets for human hair growth manipulation. c) Gene expression profiling points to additional key players in human hair cycle control with potential for future therapeutic targets.
Subjects/Keywords: 616.4; hair cycle; human hair follicle; Systems biology; Biological rhythms; Mathematical modelling; clock genes
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APA (6th Edition):
Al-Nuaimi, Y. M. (2011). A systems biology approach to the human hair cycle. (Doctoral Dissertation). University of Manchester. Retrieved from https://www.research.manchester.ac.uk/portal/en/theses/a-systems-biology-approach-to-the-human-hair-cycle(a576aff0-5fbe-4db6-9e13-8211f07e2883).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549039
Chicago Manual of Style (16th Edition):
Al-Nuaimi, Yusur Mamoon. “A systems biology approach to the human hair cycle.” 2011. Doctoral Dissertation, University of Manchester. Accessed January 27, 2021.
https://www.research.manchester.ac.uk/portal/en/theses/a-systems-biology-approach-to-the-human-hair-cycle(a576aff0-5fbe-4db6-9e13-8211f07e2883).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549039.
MLA Handbook (7th Edition):
Al-Nuaimi, Yusur Mamoon. “A systems biology approach to the human hair cycle.” 2011. Web. 27 Jan 2021.
Vancouver:
Al-Nuaimi YM. A systems biology approach to the human hair cycle. [Internet] [Doctoral dissertation]. University of Manchester; 2011. [cited 2021 Jan 27].
Available from: https://www.research.manchester.ac.uk/portal/en/theses/a-systems-biology-approach-to-the-human-hair-cycle(a576aff0-5fbe-4db6-9e13-8211f07e2883).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549039.
Council of Science Editors:
Al-Nuaimi YM. A systems biology approach to the human hair cycle. [Doctoral Dissertation]. University of Manchester; 2011. Available from: https://www.research.manchester.ac.uk/portal/en/theses/a-systems-biology-approach-to-the-human-hair-cycle(a576aff0-5fbe-4db6-9e13-8211f07e2883).html ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549039
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