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You searched for subject:(Babesia divergens). Showing records 1 – 3 of 3 total matches.

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Texas A&M University

1. Spencer, Angela M. Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island.

Degree: MS, Veterinary Parasitology, 2006, Texas A&M University

A Babesia sp. isolated from eastern cottontail rabbits (Sylvilagus floridanus) is morphologically similar and genetically identical, based on SSU rRNA gene comparisons, to two agents responsible for human babesiosis in North America and is closely related to the European parasite, Babesia divergens. The ribosomal RNA (rRNA) internal transcribed spacer regions (ITS1 and ITS2) and the 5.8S rRNA genes of Babesia isolates were sequenced and analyzed. The rRNA ITS region sequences of three isolates, one each from Kentucky, Massachusetts and Great Britain, considered Babesia divergens-like organisms, were compared to two Babesia microti isolates, two Babesia odocoilei isolates and a well defined Babesia divergens isolate. The two B. divergenslike isolates from North America shared identical rRNA ITS1-5.8S-ITS2 region sequences, and the clones of these isolates clustered into one clade in three phylogenetic analyses, suggesting that these isolates are conspecific. In vitro comparison of host erythrocyte specificity between the rabbit Babesia sp. and B. divergens was employed to discriminate between the two organisms and to determine the usefulness of in vitro techniques for Babesia sp. characterization. In vitro growth of the rabbit Babesia sp. was supported in human and cottontail rabbit erythrocytes, but not in bovine cells. Babesia divergens in vitro growth was supported in human and bovine erythrocytes, but not in cottontail rabbit cells. Morphological characteristics and size differences also distinguished the two parasites from one another. The erythrocyte specificity and parasite size differences reported in this study agree with previous in vivo results and validate the use of in vitro methods for characterization of Babesia species. Advisors/Committee Members: Holman, Patricia J. (advisor), Craig, Tom M. (committee member), Magill, Clint (committee member), Snowden, Karen F. (committee member).

Subjects/Keywords: Babesia; Babesia divergens; zoonotic Babesia

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APA (6th Edition):

Spencer, A. M. (2006). Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/4175

Chicago Manual of Style (16th Edition):

Spencer, Angela M. “Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island.” 2006. Masters Thesis, Texas A&M University. Accessed April 13, 2021. http://hdl.handle.net/1969.1/4175.

MLA Handbook (7th Edition):

Spencer, Angela M. “Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island.” 2006. Web. 13 Apr 2021.

Vancouver:

Spencer AM. Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island. [Internet] [Masters thesis]. Texas A&M University; 2006. [cited 2021 Apr 13]. Available from: http://hdl.handle.net/1969.1/4175.

Council of Science Editors:

Spencer AM. Molecular and in vitro characterization of a Babesia divergens-like agent from eastern cottontail rabbits (Sylvilagus floridanus) on Nantucket Island. [Masters Thesis]. Texas A&M University; 2006. Available from: http://hdl.handle.net/1969.1/4175

2. Jalovecka, Marie. Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications.

Degree: Docteur es, Biologie Santé, 2017, Nantes, Ecole nationale vétérinaire

Du fait de l'incidence croissante des infections à Babesia spp., Protozoaire parasite transmis par les tiques, la babésiose est considérée comme maladie émergente en médecine humaine et vétérinaire. Cette thèse apporte un aperçu de la biologie de deux agents principaux de la babésiose humaine, Babesia microti etBabesia divergens. Un modèle quantifié du parasite Babesia est proposé, permettant une étude détaillée de son cycle de vie et l'identification de molécules jouant un rôle dans son acquisition/transmission par le vecteur Ixodes ricinus. Des informations nouvelles et détaillées sur la dissémination de Babesia dans les tissus de la tique sont apportées par les techniques de visualisation/quantification développées. Le développement parasitaire dans les glandes salivaires est particulièrement étudié, car premier site responsable de la transmission du vecteur à l'hôte. Par inactivation ciblée de gènes, nous avons exploré les voies du système immunitaire de la tique, dont les molécules effectrices, et évalué leur rôle dans l'acquisition de Babesia. Une étude détaillée de l'engagement de Babesia dans la phase sexuée est réalisée, en suivant sa cinétique sous l'effet de divers stimuli. De plus, une voie nouvelle de lutte antiparasitaire est proposée envalidant le protéasome de Babesia en tant que cible thérapeutique. D'une façon générale, les travaux présentés élargissent les connaissances actuelles de la biologie du parasite Babesia incluant les interactions moléculaires à l'interface tique-Babesia et contribuent donc au contrôle de la babésiose.

Growing incidence of infections caused by the ticktransmittedprotozoan parasite Babesia spp. definesbabesiosis as an emerging disease from the aspect ofhuman and veterinary medicine. The thesis provides aninsight to biology of two main agents of humanbabesiosis, Babesia microti and Babesia divergens. Weintroduce here the fully optimized quantification model ofBabesia parasite enabling the detailed investigation ofthe parasite developmental cycle and identification ofmolecules playing a role in its acquisition andtransmission by the vector Ixodes ricinus. Novel anddetailed information about Babesia dissemination withinthe tick tissues are given by newly implementedvisualization and quantification techniques. Specialemphasis is paid to parasite development in the ticksalivary glands, the primary site responsible for parasitetransmission from the vector into the host. Using genespecificsilencing we screen the tick immune pathwaysincluding effector molecules and evaluate their role inBabesia acquisition. We also provide a detailed view toBabesia parasite sexual commitment by monitoring itskinetics upon various stimuli. Moreover, a new directionof anti-babesial therapy is proposed by validation of theBabesia proteasome as a drug target. Overall, theresearch presented in the thesis extends the currentknowledge of the Babesia parasite biology includingmolecular interactions at the tick-Babesia interface andthereby could significantly contribute to a potentialcontrol of…

Advisors/Committee Members: Malandrin, Laurence (thesis director).

Subjects/Keywords: Babesia divergens; Babesia microti; Transmission; Tiques; Interactions immunitaires; Voies de signalisation; Engagement sexuel; Proteasome; Babesia divergens; Babesia microti; Transmission model; Tick; Immune interactions; Signalling pathways; Sexual xommitment; Proteasome

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APA (6th Edition):

Jalovecka, M. (2017). Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications. (Doctoral Dissertation). Nantes, Ecole nationale vétérinaire. Retrieved from http://www.theses.fr/2017ONIR101F

Chicago Manual of Style (16th Edition):

Jalovecka, Marie. “Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications.” 2017. Doctoral Dissertation, Nantes, Ecole nationale vétérinaire. Accessed April 13, 2021. http://www.theses.fr/2017ONIR101F.

MLA Handbook (7th Edition):

Jalovecka, Marie. “Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications.” 2017. Web. 13 Apr 2021.

Vancouver:

Jalovecka M. Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications. [Internet] [Doctoral dissertation]. Nantes, Ecole nationale vétérinaire; 2017. [cited 2021 Apr 13]. Available from: http://www.theses.fr/2017ONIR101F.

Council of Science Editors:

Jalovecka M. Établissement du modèle de laboratoire Babesia et ses applications expérimentales : Establishment of Babesia laboratory model and its experimental applications. [Doctoral Dissertation]. Nantes, Ecole nationale vétérinaire; 2017. Available from: http://www.theses.fr/2017ONIR101F


University of Helsinki

3. Isomursu, Marja. Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus.

Degree: Eläinlääketieteellinen tiedekunta; Helsingfors universitet, Veterinärmedicinska fakulteten, 1996, University of Helsinki

Tutkielmassa esitellään saatavilla olleen kirjallisuuden perusteella useimmat porolla esiintyvät loislajit tai -suvut. Tutkielma jakautuu neljään osaan: alkueläimet (Protozoa), laakamadot (Platyhelminthes), pyörömadot (Nemathelminthes) ja niveljalkaiset (Arthropoda). Jokaisen osan lopussa on kirjallisuusluettelo. Kunkin loislajin tai -suvun kohdalla kasitellään morfologiaa, esiintymistä, epidemiologiaa, patogeneesiä, kliinistä merkitysotä, immuniteettia, diagnosointia ja lääkitystä. Porolle merkittävimmät ja tutkituimmat lajit ovat saaneet eniten tilaa. Näita ovat kurmu eli ihosaivartaja (Hypoderma tarandi), saulakka eli nenäsaivartaja (Cephenemyia trompe), aivomato (Elaphostrongylus rangiferi) ja keuhkomato (Dictyocaulus eckerti).

Vain tiivistelmä.

Subjects/Keywords: loinen; Trypanosoma cervi; Giardia; Entamoeba; Eimeria; Isospora rangiferi; Sarcocystis; Besnoitia tarandi; Babesia divergens; poro; loiset; Patologinen anatomia; Patologisk anatomi; Pathological Anatomy; loinen; Trypanosoma cervi; Giardia; Entamoeba; Eimeria; Isospora rangiferi; Sarcocystis; Besnoitia tarandi; Babesia divergens

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Isomursu, M. (1996). Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus. (Thesis). University of Helsinki. Retrieved from http://hdl.handle.net/1975/1156

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Isomursu, Marja. “Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus.” 1996. Thesis, University of Helsinki. Accessed April 13, 2021. http://hdl.handle.net/1975/1156.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Isomursu, Marja. “Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus.” 1996. Web. 13 Apr 2021.

Vancouver:

Isomursu M. Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus. [Internet] [Thesis]. University of Helsinki; 1996. [cited 2021 Apr 13]. Available from: http://hdl.handle.net/1975/1156.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Isomursu M. Poron (Rangifer tarandus tarandus) loiset - kirjallisuuskatsaus. [Thesis]. University of Helsinki; 1996. Available from: http://hdl.handle.net/1975/1156

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.