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Addis Ababa University
1.
Alemayehu, Sileshi.
EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
.
Degree: 2015, Addis Ababa University
URL: http://etd.aau.edu.et/dspace/handle/123456789/6274 
► Evaluation of ceftriaxone utilization in medical and emergency wards of Tikur Anbessa Specialized hospital By: Alemayehu Sileshi Addis Ababa University, 2015 Background: Ceftriaxone is one…
(more)
▼ Evaluation of ceftriaxone utilization in medical and emergency wards of Tikur Anbessa Specialized hospital By: Alemayehu Sileshi Addis Ababa University, 2015 Background: Ceftriaxone is one of the most commonly used antibiotics due to its high antibacterial potency, wide spectrum of activity and low potential for toxicity. The global trend shows misuse of this drug. Objective: This study was conducted to evaluate the appropriateness of ceftriaxone
use in medical and emergency wards of Tikur Anbessa Specialized Hospital (TASH). Methods: A prospective cross-sectional study was conducted by reviewing medication records of 314 patients who received ceftriaxone during hospitalization at TASH between February 1 and June 30, 2014. Drug
use evaluation (DUE) was conducted to determine whether ceftriaxone was being used appropriately based on six criteria namely indication for
use, dose, frequency of administration, duration of treatment, drug-drug interaction (DDI) and culture and sensitivity (C&S) test. The evaluation was made as per the protocol currently developed. Additionally, areas which need intervention were identified and interventions were implemented.
Results: The prescribing rate of ceftriaxone was found to be very high (58% point prevalence). Ceftriaxone
use was empiric in 274 cases (87.3%) and specific in 5 cases (1.6%). The most common indication for ceftriaxone
use was pneumonia; observed in 110 cases (35.0%). The most common daily dosage, frequency of administration and duration of treatment with ceftriaxone were 2g (88.9%), twice-daily (98.4%) and 8-14 days (46.2%), respectively. Inappropriate
use of ceftriaxone was observed in most cases
iv
(87.9%), the greatest proportion of which was attributed to inappropriate frequency of administration (80.3%), followed by absence of C&S test (53.2%). Conclusions: This study revealed that the inappropriate
use of ceftriaxone was very high in the medical and emergency wards of TASH. This may lead to emergence of resistant pathogens which in turn lead to treatment failure and increased cost of therapy. Therefore, adherence to current evidence-based guidelines is recommended. Key words: Ceftriaxone, drug
use evaluation,
antibiotic, rational
use
Advisors/Committee Members: Admasu Tenna(Dr.) (advisor).
Subjects/Keywords: Ceftriaxone; drug use evaluation; antibiotic; rational use.
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APA (6th Edition):
Alemayehu, S. (2015). EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
. (Thesis). Addis Ababa University. Retrieved from http://etd.aau.edu.et/dspace/handle/123456789/6274
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Alemayehu, Sileshi. “EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
.” 2015. Thesis, Addis Ababa University. Accessed December 10, 2019.
http://etd.aau.edu.et/dspace/handle/123456789/6274.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Alemayehu, Sileshi. “EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
.” 2015. Web. 10 Dec 2019.
Vancouver:
Alemayehu S. EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
. [Internet] [Thesis]. Addis Ababa University; 2015. [cited 2019 Dec 10].
Available from: http://etd.aau.edu.et/dspace/handle/123456789/6274.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Alemayehu S. EVALUATION OF CEFTRIAXONE UTILIZATION IN MEDICAL AND EMERGENCY WARDS OF TIKUR ANBESSA SPECIALIZED HOSPITAL
. [Thesis]. Addis Ababa University; 2015. Available from: http://etd.aau.edu.et/dspace/handle/123456789/6274
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Lethbridge
2.
Jaja, Oyindamola.
A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
.
Degree: 2017, University of Lethbridge
URL: http://hdl.handle.net/10133/5000
► Antibiotics changed the world and radically transformed diseases that were once deadly into manageable health problems. The aim of this study was to evaluate the…
(more)
▼ Antibiotics changed the world and radically transformed diseases that were once deadly into manageable health problems. The aim of this study was to evaluate the public knowledge and attitude regarding antibiotics use and antibiotic resistance in southwest Alberta. A cross-sectional face to face survey of individuals aged 18 years and older and residents of Lethbridge, Coaldale, Coal Hurst, Fort Macleod, Raymond and Taber was conducted. Of the 219 respondents, the majority agreed that antibiotics can kill bacteria (81.4%), whereas a notable proportion (43%) agreed that antibiotics can kill viruses. About 55% of the respondents indicated that antibiotic was effective for treating most sore-throat while over 30% agreed antibiotics are used for treating most common cold and cough. Marital status, education, ethnicity and antibiotics resistance education were predictors of antibiotic knowledge. Marital status, age, education, ethnicity and antibiotics resistance education were predictors of antibiotic attitude.
Subjects/Keywords: Antibiotic use; Public Knowledge; Public Attitude; Antibiotic Resistance
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APA (6th Edition):
Jaja, O. (2017). A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
. (Thesis). University of Lethbridge. Retrieved from http://hdl.handle.net/10133/5000
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Jaja, Oyindamola. “A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
.” 2017. Thesis, University of Lethbridge. Accessed December 10, 2019.
http://hdl.handle.net/10133/5000.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Jaja, Oyindamola. “A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
.” 2017. Web. 10 Dec 2019.
Vancouver:
Jaja O. A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
. [Internet] [Thesis]. University of Lethbridge; 2017. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10133/5000.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Jaja O. A survey of public knowledge and attitude related to antibiotic use and antibiotic resistance in Southwest Alberta
. [Thesis]. University of Lethbridge; 2017. Available from: http://hdl.handle.net/10133/5000
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Ottawa
3.
Dickson, Catherine.
The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
.
Degree: 2016, University of Ottawa
URL: http://hdl.handle.net/10393/34862
► N. Gonorrhoeae is a major public health concern due to its capacity to develop antibiotic resistance and its potential complications including pelvic inflammatory disease, epididymitis,…
(more)
▼ N. Gonorrhoeae is a major public health concern due to its capacity to develop antibiotic resistance and its potential complications including pelvic inflammatory disease, epididymitis, infertility, and disseminated infection. In order to keep up with resistance trends, the treatment recommendations for gonorrhea have changed frequently. In other areas of medicine, guideline adherence has been shown to be limited, even without frequent guideline changes. In the case of gonorrhea, inappropriate treatment can have serious individual and public health implications, making the quality of and compliance with clinical guidelines critical. This thesis is a three-part mixed methods research project assessing the development and uptake of gonorrhea treatment guidelines. We conducted a systematic review of current gonorrhea treatment guidelines and used the AGREE II tool to assess the quality of guideline development (Chapter 2). We observed that guideline quality varied greatly with many guidelines having weaknesses in their use of existing evidence to develop recommendations, their reporting of potential conflicts of interest and how they were addressed, and their consideration of barriers to the implementation of their recommendations. We then assessed physician adherence to first-line treatment recommendations in Ontario by conducting a segmented time series analysis of Ontario gonorrhea treatment data from iPHIS, the province’s reportable disease database (Chapter 3). Following the introduction of new guidelines that recommended substantial changes from current practice, we found very dramatic drops in guidelines adherence that then improved slowly over time. We then explored the use of process mapping as a tool to look at the local management of cases in the City of Ottawa by following them across the various possible treatment pathways (Chapter 4). Here, we noted differences in practice between the management of cases at Ottawa Public Health’s Sexual Health Clinic and the management of cases elsewhere in the community.
Subjects/Keywords: Gonorrhea;
STI;
Clinical guidelines;
Antibiotic use
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APA (6th Edition):
Dickson, C. (2016). The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
. (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/34862
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Dickson, Catherine. “The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
.” 2016. Thesis, University of Ottawa. Accessed December 10, 2019.
http://hdl.handle.net/10393/34862.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Dickson, Catherine. “The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
.” 2016. Web. 10 Dec 2019.
Vancouver:
Dickson C. The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
. [Internet] [Thesis]. University of Ottawa; 2016. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10393/34862.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Dickson C. The Management of Gonococcal Infections and the Development and Use of Treatment Guidelines
. [Thesis]. University of Ottawa; 2016. Available from: http://hdl.handle.net/10393/34862
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Kansas State University
4.
Schrag, Nora.
Measurements
of antibiotic use in United States dairy systems.
Degree: PhD, Department of Diagnostic
Medicine/Pathobiology, 2019, Kansas State University
URL: http://hdl.handle.net/2097/40083
► Methods of measuring antibiotic use were explored using data collected from a convenience sample of 29 US dairy farms for the calendar years of 2016…
(more)
▼ Methods of measuring
antibiotic use were explored
using data collected from a convenience sample of 29 US dairy farms
for the calendar years of 2016 and 2017. Multiple on-farm data
sources included handwritten records and four software systems.
Data from each source were standardized to a common format for
analysis. Antimicrobial
use is reported as regimens per cow year
with the regimens defined at the product level by route of
administration, number of administrations, time frame between first
and last administration, grams per regimen, and grams per
administration. The primary goal of this study was to identify
which measures might be useful for guiding stewardship at the farm
level, and to describe the nuances associated with different
methods of measurement. For this reason, care was taken to maintain
the association between
use and the reason for
use (detected
disease) for all measures reported.
This method of reporting
provided enough granularity to compare different methods of
antimicrobial
use measurement. Measurements of overall
use by
regimens per cow year indicate that most
use occurs as intramammary
treatments and cephalosporins are the most commonly used
antibiotic
class.
Use measured by grams per cow year indicates that both Dry
Cow therapy and non-intramammary (Other Treatments) contribute
significantly to overall
use, and
use in the penicillin class
predominates. Comparisons of measures by regimens, grams, defined
daily doses (DDD), defined course doses (DCD) and days of therapy
(DOT) are evaluated at the farm level. With the exception of grams,
all comparisons of these measures have correlations greater than
0.7 for all categories of
use. Potency confounds measures of active
substance weight causing
use measured as grams of antimicrobial to
not correlate as well with other measures (correlations <0.5).
This lack of correlation is especially apparent for dry cow therapy
where the correlation between grams and other measures is -0.06.
These comparisons raise questions about the relationship between
use measures and resistance selection pressure. Further study is
needed to identify the exact relationship between
use measures and
resistance selection pressure, as well as to identify treatment
outcome parameters that should be assessed to ensure that animal
welfare is appropriately monitored as antimicrobial stewardship is
advanced.
Advisors/Committee Members: Michael D. Apley.
Subjects/Keywords: Antibiotic,
Antimicrobial, Use, Metrics, Dairy, Cattle; Antibiotic,
Antimicrobial, Use, Metrics, Dairy, Cattle
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APA ·
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APA (6th Edition):
Schrag, N. (2019). Measurements
of antibiotic use in United States dairy systems. (Doctoral Dissertation). Kansas State University. Retrieved from http://hdl.handle.net/2097/40083
Chicago Manual of Style (16th Edition):
Schrag, Nora. “Measurements
of antibiotic use in United States dairy systems.” 2019. Doctoral Dissertation, Kansas State University. Accessed December 10, 2019.
http://hdl.handle.net/2097/40083.
MLA Handbook (7th Edition):
Schrag, Nora. “Measurements
of antibiotic use in United States dairy systems.” 2019. Web. 10 Dec 2019.
Vancouver:
Schrag N. Measurements
of antibiotic use in United States dairy systems. [Internet] [Doctoral dissertation]. Kansas State University; 2019. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/2097/40083.
Council of Science Editors:
Schrag N. Measurements
of antibiotic use in United States dairy systems. [Doctoral Dissertation]. Kansas State University; 2019. Available from: http://hdl.handle.net/2097/40083
University of Ottawa
5.
Jeong, Dahn.
The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
.
Degree: 2015, University of Ottawa
URL: http://hdl.handle.net/10393/32178
► Methicillin-resistant Staphylococcus aureus (MRSA) is a growing concern in Canada especially in Aboriginal communities in remote regions. The northern and remote communities possess some or…
(more)
▼ Methicillin-resistant Staphylococcus aureus (MRSA) is a growing concern in Canada especially in Aboriginal communities in remote regions. The northern and remote communities possess some or many of the risk factors that are identified in previous research to be associated with Community-Associated Methicillin-resistant Staphylococcus aureus (CA-MRSA) infections such as overcrowding, challenges in maintaining personal hygiene and limited access to healthcare. CA-MRSA spreads rapidly in the communities. It is known to not only affect young and healthy individuals, but it is also associated with high morbidity and mortality rates. Furthermore, antibiotic resistance in CA-MRSA is increasing in Canada. It is known that inappropriate and greater use of antibiotics is associated with increased antibiotic resistance. Resistant CA-MRSA infections are more difficult to treat. To reduce and to control the antibiotic resistance, monitoring the prevalence of CA-MRSA and the changing antibiotic susceptibility profiles at the population level, especially in highly affected communities, is crucial. By monitoring this trend, it will enable healthcare practitioners to provide more adequate and appropriate treatment. To our knowledge, there was no community-based study that examined the epidemiology of CA-MRSA skin and soft-tissue infections (SSTIs) in First Nations communities in Canada at large scale, and the knowledge on the risk factors, outcomes and antibiotic susceptibility profiles is still very limited.
This study aimed to describe the local epidemiology of SSTIs at the community level in selected First Nations communities as well as to describe the antibiotic use to treat SSTIs and the antibiotic susceptibility patterns of CA-MRSA. A retrospective chart review was conducted in 12 nursing stations in the First Nations communities across 5 provinces in Canada. The charts of individuals over 18 years of age who had received service at the nursing station in the previous 12 months, starting retrospectively from the date of collection, were reviewed in this study. Each antibiotic prescription that was noted in the chart in this period prior to chart review was recorded in the antibiotic tracking case report form. Data collected included demographics, indication for antibiotic use, antibiotic prescription parameters and patient outcomes.
In total, of 372 patient charts reviewed, 224 patient charts contained at least one case (an encounter that resulted in an antibiotic prescription during the study period). Of those 224 charts, 459 cases were recorded and, of those, 137 cases had a diagnosis of an SSTI. In the 65 patients accounting for all cases of SSTI patients, more than 80% of the study population were under the age of 50. The prevalence of impaired renal function was low, diabetes was present in 20% of cases, cardiac disease was present in 15% of cases, and reported alcohol misuse was present in 30% of cases. The presence of indwelling devices was very rare. There were 137 cases of SSTIs over 372 charts reviewed in total. The…
Subjects/Keywords: CA-MRSA;
SSTI;
First Nations communities;
Antibiotic resistance;
Antibiotic use;
Remote regions
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Record Details
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APA ·
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CSE |
Export
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Manager
APA (6th Edition):
Jeong, D. (2015). The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
. (Thesis). University of Ottawa. Retrieved from http://hdl.handle.net/10393/32178
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Jeong, Dahn. “The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
.” 2015. Thesis, University of Ottawa. Accessed December 10, 2019.
http://hdl.handle.net/10393/32178.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Jeong, Dahn. “The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
.” 2015. Web. 10 Dec 2019.
Vancouver:
Jeong D. The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
. [Internet] [Thesis]. University of Ottawa; 2015. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10393/32178.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Jeong D. The Use of Antibiotics in the Treatment of Skin and Soft Tissue Infections in Selected Canadian First Nations Communities
. [Thesis]. University of Ottawa; 2015. Available from: http://hdl.handle.net/10393/32178
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
6.
Collineau, Lucie.
Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe.
Degree: Docteur es, Epidemiologie, santé publique vétérinaire, 2016, Nantes, Ecole nationale vétérinaire; Oniris – Ecole Nationale Vétérinaire, Agroalimentaire et de l’Alimentation (Nantes Atlantique)
URL: http://www.theses.fr/2016ONIR091F
► La résistance aux antibiotiques est une menace sérieuse pour la santé publique en Europe, entrainant une augmentation des coûts de la santé, des échecs thérapeutiques,…
(more)
▼ La résistance aux antibiotiques est une menace sérieuse pour la santé publique en Europe, entrainant une augmentation des coûts de la santé, des échecs thérapeutiques, et de la mortalité (ECDC, 2011). Le développement de l'antibiorésistance est principalement lié à la consommation d'antibiotiques chez l'Homme et les animaux. Depuis le début des années 2000, les pays européens ont limité cette consommation et en 2006, l'UE a interdit l'utilisation d'antibiotiques comme promoteurs de croissance. Ceci a favorisé le développement de diverses alternatives à l'utilisation d'antibiotiques. L'objectif principal de ce projet de thèse est d'évaluer l'utilisation d'alternatives spécifiques et non spécifiques à l'utilisation d'antibiotiques dans les élevages de porcs européens. L'étude sera organisée en trois parties: i) une évaluation technique, visant à quantifier le lien entre l'utilisation d'antibiotiques et les performances techniques des élevages, ii) une évaluation économique, basée sur une analyse coût-efficacité et coûts-bénéfices des stratégies alternatives aux antibiotiques et iii) une évaluation psychosociologique, décrivant les attitudes et les comportements des éleveurs, vétérinaires et scientifiques vis-à-vis de l'utilisation d'antibiotiques en élevage porcin. Ce projet impliquera à la fois la réalisation de visites d'élevages français, l'utilisation d'outils statistiques variés et de méthodes de recherche qualitative et d'évaluation des risques. Ainsi, ce projet fournira les bases d'une compréhension globale des facteurs techniques, économiques et psychosociologiques qui orientent les décisions des éleveurs et des vétérinaires au sujet de la santé et de la production porcine et qui, par conséquent, définissent les possibles interventions sur l'utilisation d'antibiotiques. Cette étude fait partie du projet de recherche du Consortium MINAPIG financé par le programme Emida Era-Net. Un financement supplémentaire est fourni par l'Office vétérinaire fédéral suisse.
Antimicrobial resistance is a serious threat to public health in Europe, leading to mounting healthcare costs, treatment failure, and deaths (ECDC, 2011). The development of antimicrobial resistance is mainly due to antimicrobial consumption in humans and animals. From early 2000s, European countries have implemented restriction measures and in 2006, EU banned the use of antibiotics as growth promoters in animal feed. This has promoted the development of various alternatives to antimicrobial. The main objective of this PhD project is to assess and evaluate specific and unspecific alternatives to antimicrobials in the European pig industry. The study will be organised in three main parts: i) a technical assessment, quantifying the link between antimicrobial use and technical performances of the pig farms, ii) an economic evaluation, conducting cost-effectiveness and cost-benefit analyses of alternative strategies in comparison with antimicrobial usage, and iii) a psycho-sociological evaluation, describing farmers, veterinarians and pig experts attitudes,…
Advisors/Committee Members: Belloc, Catherine (thesis director), Stärk, Katharina (thesis director).
Subjects/Keywords: Utilisation des antibiotiques,; Bonnes pratiques; Déterminants; Antimicrobial use; Antibiotic; Antimicrobial stewardship
Record Details
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APA ·
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MLA ·
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CSE |
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Manager
APA (6th Edition):
Collineau, L. (2016). Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe. (Doctoral Dissertation). Nantes, Ecole nationale vétérinaire; Oniris – Ecole Nationale Vétérinaire, Agroalimentaire et de l’Alimentation (Nantes Atlantique). Retrieved from http://www.theses.fr/2016ONIR091F
Chicago Manual of Style (16th Edition):
Collineau, Lucie. “Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe.” 2016. Doctoral Dissertation, Nantes, Ecole nationale vétérinaire; Oniris – Ecole Nationale Vétérinaire, Agroalimentaire et de l’Alimentation (Nantes Atlantique). Accessed December 10, 2019.
http://www.theses.fr/2016ONIR091F.
MLA Handbook (7th Edition):
Collineau, Lucie. “Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe.” 2016. Web. 10 Dec 2019.
Vancouver:
Collineau L. Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe. [Internet] [Doctoral dissertation]. Nantes, Ecole nationale vétérinaire; Oniris – Ecole Nationale Vétérinaire, Agroalimentaire et de l’Alimentation (Nantes Atlantique); 2016. [cited 2019 Dec 10].
Available from: http://www.theses.fr/2016ONIR091F.
Council of Science Editors:
Collineau L. Quantify, Explain and Reduce Antimicrobial Usage in Pig Production in Europe : Quantifier, Comprendre et Réduire l’Utilisation des Antibiotiques en Elevage Porcin en Europe. [Doctoral Dissertation]. Nantes, Ecole nationale vétérinaire; Oniris – Ecole Nationale Vétérinaire, Agroalimentaire et de l’Alimentation (Nantes Atlantique); 2016. Available from: http://www.theses.fr/2016ONIR091F
Univerzitet u Beogradu
7.
Jakovljević, Emil I., 1980-.
Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece.
Degree: Farmaceutski fakultet, 2015, Univerzitet u Beogradu
URL: https://fedorabg.bg.ac.rs/fedora/get/o:9439/bdef:Content/get
► Farmakologija - Farmakoepidemiologija / Pharmacology - Pharmacoepidemiology
Rezistencija bakterija predstavlja veliki zdravstveni problem. Poznato je da je neracionalna upotreba antibiotika jedan od najznačajnijih uzroka porasta…
(more)
▼ Farmakologija - Farmakoepidemiologija /
Pharmacology - Pharmacoepidemiology
Rezistencija bakterija predstavlja veliki
zdravstveni problem. Poznato je da je neracionalna upotreba
antibiotika jedan od najznačajnijih uzroka porasta rezistencije.
Posebno su ugrožena deca jer su najčešće izložena ovim lekovima.
Cilj ove prospektivne jednogodišnje studije bio je da se utvrdi
obim i struktura upotrebe antibiotika na Institutu za zdravstvenu
zaštitu dece i omladine Vojvodine u Novom Sadu, kao i da se sagleda
rezistencija i multirezistencija najčešće izolovanih bakterija kod
dece u zavisnosti od uzrasta, pola, vrste bolesničkog materijala,
godišnjih doba i klinike na kojoj su deca smeštena. Obim upotrebe
antibiotika procenjen je primenom metode definisane dnevne doze
(DDD) na 100 bolesničko-obskrbnih dana (BOD), uz primenu
anatomsko-terapijsko-hemijske (ATC) klasifikacije lekova. Za
procenu rezistencije i multirezistencije bakterija korišten je
softver WHONET 5.4, razvijen od strane Svetske Zdravstvene
Organizacije u svrhu ovakvih epidemioloških analiza. Rezultati su
prikazani grafički i tabelarno uz statističku procenu razlika.
Upotreba antibiotika: Prosečan obim upotrebe antibiotika na
IZZZDIOV bio je 37,74 DDD/100BOD, s time što je na Klinici za
hirurgiju bila 56,66, na Klinici za pedijatriju kod deca uzrasta do
2 godine 23,17, na Klinici za pedijatriju kod dece uzrasta 2-18
godina 44,10 i na Klinici za habilitaciju i rehabilitaciju 6,04
DDD/100BOD. Obim upotrebe antibiotika tokom zime na nivou celog
IZZZDIOV bio je veći u odnosu na leto. Antibiotici su se koristili
na svim klinikama i odeljenjima, bez izuzetaka. Bakteriološki
nalazi: Od 11942 uzoraka poslatih na mikrobiološku analizu, 18,14%
(2168/11952) bilo je bakteriološki pozitivno, s time da su najčešće
analizirani bili uzorci krvi i urina. Značajno manje bakterija
izolovano je zimi u odnosu na leto. Najčešće izolovana bakterija
bila je Escherichia coli, a po učestalosti su sledili:
Staphylococcus aureus, koagulaza negativni Staphylococcus spp,
Klebsiella spp, Pseudomonas spp, Acinetobacter spp, Enterococcus
spp i Enterobacter spp. Bakterije izolovane kod dece uzrasta do 2
godine u proseku su bile u većem procentu rezistentnije i
multirezistentnije u odnosu na bakterije izolovane kod starije
dece...
Advisors/Committee Members: Ugrešić, Nenad, 1951-.
Subjects/Keywords: pediatric university hospital; antibiotic use;
bacterial resistance and multidrug resistance
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APA (6th Edition):
Jakovljević, Emil I., 1. (2015). Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:9439/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Jakovljević, Emil I., 1980-. “Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece.” 2015. Thesis, Univerzitet u Beogradu. Accessed December 10, 2019.
https://fedorabg.bg.ac.rs/fedora/get/o:9439/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Jakovljević, Emil I., 1980-. “Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece.” 2015. Web. 10 Dec 2019.
Vancouver:
Jakovljević, Emil I. 1. Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece. [Internet] [Thesis]. Univerzitet u Beogradu; 2015. [cited 2019 Dec 10].
Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9439/bdef:Content/get.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Jakovljević, Emil I. 1. Prospektivna studija upotrebe antibiotika i stanja
bakterijske rezistencije kofd hospitalizivane dece. [Thesis]. Univerzitet u Beogradu; 2015. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:9439/bdef:Content/get
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Universiteit Utrecht
8.
Scheer, A.
Het effect van selectief droogzetten op het ontstaan van mastitis.
Degree: 2013, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/274951
► The antibiotics covenant agreed that the use of antibiotics should be reduced. In the dairy sector, almost half of the total antibiotic use, are used…
(more)
▼ The antibiotics covenant agreed that the
use of antibiotics should be reduced. In the dairy sector, almost half of the total
antibiotic use, are used to dry cows of at the end of the lactation. In this study, the effect of selective dry off on the occurrence of mastitis determined and examines what management factors play a role in the successful selective non-drying off, at low cell count cows. Furthermore, it is calculated if selective non-drying off in the cattle industry is leading to an overall decrease in total
antibiotic use in this sector.
The test is being executed on 7 companies, a total of 42 cows are included in the test. 21 of the cows where dried off with
antibiotic in the udder, the other 21 without antibiotics. Selective non-drying-off leads to an increase in the number of cases of mastitis. 5 of the 21 cows developed clinical mastitis, compared with 0 cows in the group which where dried of with antibiotics. The literature shows that feed is an important factor to avoid mastitis. Parity and hygiene during the dry period are the biggest risk factor for the development of mastitis in the trial. Outdoor access has a positive effect on the prevention of subclinical mastitis. This is probably due to improved hygiene conditions in an outdoor run. Increased movement pattern, while the cows where walking outdoor would also be a possible cause. Selective non-drying off brings a reduction of antibiotics with them, even if there are more cases of mastitis occur. It is concluded that dry off without antibiotics more cases of mastitis entails, but if strict criteria are used, it is possible to reduce the
use of antibiotics by selective non-drying off.
Advisors/Committee Members: Jorritsma, R.
Subjects/Keywords: Diergeneeskunde; selective non-drying off, cow, antibiotic use, mastitis
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APA (6th Edition):
Scheer, A. (2013). Het effect van selectief droogzetten op het ontstaan van mastitis. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/274951
Chicago Manual of Style (16th Edition):
Scheer, A. “Het effect van selectief droogzetten op het ontstaan van mastitis.” 2013. Masters Thesis, Universiteit Utrecht. Accessed December 10, 2019.
http://dspace.library.uu.nl:8080/handle/1874/274951.
MLA Handbook (7th Edition):
Scheer, A. “Het effect van selectief droogzetten op het ontstaan van mastitis.” 2013. Web. 10 Dec 2019.
Vancouver:
Scheer A. Het effect van selectief droogzetten op het ontstaan van mastitis. [Internet] [Masters thesis]. Universiteit Utrecht; 2013. [cited 2019 Dec 10].
Available from: http://dspace.library.uu.nl:8080/handle/1874/274951.
Council of Science Editors:
Scheer A. Het effect van selectief droogzetten op het ontstaan van mastitis. [Masters Thesis]. Universiteit Utrecht; 2013. Available from: http://dspace.library.uu.nl:8080/handle/1874/274951
Halmstad University
9.
Sahoo, Krushna Chandra.
Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India.
Degree: Business and Engineering (SET), 2008, Halmstad University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1877
► Objective: To explore views of medical doctors, veterinarians and drug sellers on use of antibiotics on humans and nonhumans and on factors that influences…
(more)
▼ Objective: To explore views of medical doctors, veterinarians and drug sellers on use of antibiotics on humans and nonhumans and on factors that influences the development of resistance to antibacterial agents. Further, to look at the bi-directional relationship between antibiotic use and environment. Methods: The study was a qualitative explorative interview study, analysed using conventional content analysis. It was conducted in Orissa, India. Data were collected by face to face semi structured interview. The interviews were tape recorded and transcribed into Oriya, then translated in to English. Each paragraph or sentence was coded. Similar codes were clustered together and collapsed into sub categories and categories. The main themes were allowed to emerge, based on the relationship between categories. Findings: The main finding of the study was mishandling and abuse of antibiotics in patients as well as at professional level due to weak implementation of legislation, which appears to be the major cause of antibacterial agent resistance. Incomplete course or dose due to poverty in rural area and self medication in urban area are more common. The study also showed that climatic factors, pollution and population density are the major ecological factors which influence antibiotic prescriptions. Another major finding of this study was that, due to improper disposal system of pharmaceuticals; antibiotics are contaminating air, water and terrains which can cause major risk to aquatic and grazing animals. Conclusion: This study emphasises the need for comprehensive actions including information, training, legislation and education at all levels of drug delivery system to rationalize antibiotic use by improving prescribing pattern and creating awareness among consumers. Proper disposal of pharmaceutical wastes is required to prevent the contamination of environment from pharmaceutical pollutants. Further study is essential concerning environmental impact of antibiotics. Key words: Antibiotic use; antibiotic resistance; environment; qualitative; conventional; content analysis; veterinarians; medical doctors; drug sellers; Orissa; India.
Subjects/Keywords: Antibiotic use; antibiotic resistance; environment; qualitative; conventional; content analysis; veterinarians; medical doctors; drug sellers; Orissa; India
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APA (6th Edition):
Sahoo, K. C. (2008). Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India. (Thesis). Halmstad University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1877
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Sahoo, Krushna Chandra. “Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India.” 2008. Thesis, Halmstad University. Accessed December 10, 2019.
http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1877.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Sahoo, Krushna Chandra. “Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India.” 2008. Web. 10 Dec 2019.
Vancouver:
Sahoo KC. Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India. [Internet] [Thesis]. Halmstad University; 2008. [cited 2019 Dec 10].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1877.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Sahoo KC. Antibiotic use, environment and antibiotic resistance : A qualitative study among human and veterinary health care professionals in Orissa, India. [Thesis]. Halmstad University; 2008. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-1877
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
10.
Amadeo, Brice.
Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy.
Degree: Docteur es, Sciences, technologie, santé. Epidémiologie et santé publique, 2010, Université de Bordeaux Segalen
URL: http://www.theses.fr/2010BOR21742
► La maitrise de la résistance bactérienne et l’utilisation prudente des antibiotiques à l’hôpital constituent des enjeux majeurs pour les autorités de santé dans tous les…
(more)
▼ La maitrise de la résistance bactérienne et l’utilisation prudente des antibiotiques à l’hôpital constituent des enjeux majeurs pour les autorités de santé dans tous les pays européens. Toutefois, les connaissances en matière de consommation des antibiotiques et de politique de bon usage des antibiotiques dans les établissements sont limitées. Dans ce contexte, le travail de cette thèse permet de donner une meilleure vision de la consommation des antibiotiques dans les pays européens à partir des données de surveillance disponibles. Il apporte également des cibles d’amélioration de la prescription des antibiotiques et identifie plusieurs indicateurs de qualité pour mener à bien une politique de bon usage des antibiotiques. De plus, ce travail utilise le modèle des hôpitaux français pour identifier des critères d’ajustement de la consommation des antibiotiques facilement disponibles qui sont essentiels à mettre en œuvre pour établir des comparaisons entre les différents hôpitaux. Il s’intéresse également à la relation entre la politique de bon usage des antibiotiques dans les hôpitaux et une moindre consommation des antibiotiques. En conclusion, les données de surveillance de la consommation des antibiotiques ont donc permis de répondre à plusieurs hypothèses de recherche et de dégager de nouveaux axes de réflexions.
The control of bacterial resistance and the prudent use of antibiotics in hospitals are major challenges for health authorities in all European countries. However, little is known regarding antibiotic consumption and antibiotic policies in hospitals. In this context, this thesis provides insight into the antibiotic consumption using available survey databases. It also identifies targets for quality improvement and several quality indicators which are essencial to carry out a prudent use antibiotic policy. Moreover, the model of French hospitals was used to explore easily available adjustment criteria for the antibiotic consumption which are crucial to implement comparisons between different types of hospitals. This work brings light onto the relationship between the antibiotic policy and a low level of antibiotic use in French hospitals. In conclusion, survey databases have enabled us to answer several research assumptions and to generate new horizons of reflection.
Advisors/Committee Members: Fourrier, Annie (thesis director).
Subjects/Keywords: Consommation des antibiotiques; Critères d’ajustement; Politique antibiotique; France; Europe; Antibiotic use; Adjustement criteria; Antibiotic policy; France; Europe
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APA ·
Chicago ·
MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Amadeo, B. (2010). Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy. (Doctoral Dissertation). Université de Bordeaux Segalen. Retrieved from http://www.theses.fr/2010BOR21742
Chicago Manual of Style (16th Edition):
Amadeo, Brice. “Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy.” 2010. Doctoral Dissertation, Université de Bordeaux Segalen. Accessed December 10, 2019.
http://www.theses.fr/2010BOR21742.
MLA Handbook (7th Edition):
Amadeo, Brice. “Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy.” 2010. Web. 10 Dec 2019.
Vancouver:
Amadeo B. Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy. [Internet] [Doctoral dissertation]. Université de Bordeaux Segalen; 2010. [cited 2019 Dec 10].
Available from: http://www.theses.fr/2010BOR21742.
Council of Science Editors:
Amadeo B. Consommation des Antibiotiques dans les Etablissements de Santé : description, Critères d’Ajustement et Relation avec la Politique de Bon Usage des Antibiotiques : Antibiotic consumption in hospitals : description, Adjustment criteria and Relationship with Antibiotic Policy. [Doctoral Dissertation]. Université de Bordeaux Segalen; 2010. Available from: http://www.theses.fr/2010BOR21742
11.
Dumartin, Catherine.
Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals.
Degree: Docteur es, Sciences, technologie, santé. Epidémiologie et santé publique, 2010, Université de Bordeaux Segalen
URL: http://www.theses.fr/2010BOR21744
► Pour enrayer la progression des résistances bactériennes aux antibiotiques (AB), liée, en partie, à un mésusage de ces médicaments, l’Union européenne (UE) s’est mobilisée en…
(more)
▼ Pour enrayer la progression des résistances bactériennes aux antibiotiques (AB), liée, en partie, à un mésusage de ces médicaments, l’Union européenne (UE) s’est mobilisée en adoptant, en 2001, une recommandation prônant un usage prudent des AB. En 2008, sous l’égide de la Commission européenne, nous avons évalué la mise en œuvre de cette recommandation et son impact dans les Etats membres, et nous avons réalisé une analyse du cadre juridique développé dans 12 de ces Etats. De plus, une étude a été conduite entre 2005 et 2009 sur 74 établissements de santé (ES) volontaires du Sud-Ouest de la France pour identifier l’impact du cadre juridique sur l’évolution des consommations d’AB. Les Etats de l’UE ont engagé un grand nombre d’actions pour rationaliser l’utilisation des AB, mais des progrès dans le champ de l’évaluation demeurent nécessaires. Il ressort de l’analyse sur 12 Etats qu’un cadre juridique plus important semble associé à une plus grande sensibilisation de la population générale et à une meilleure maîtrise de la consommation de fluoroquinolones. Dans les ES du Sud-Ouest, les politiques locales de bon usage des AB ont progressé. Une combinaison de mesures telles que la présence d’un référent « AB », l’organisation de formations et le recours à des prescriptions à durée limitée, était associée à une réduction significative de la consommation des fluoroquinolones. L’amélioration de l’utilisation des AB implique de préciser les conditions d’efficacité optimale des actions et de renforcer l’encadrement juridique dans les Etats de l’UE, notamment en matière de surveillance, d’évaluation, de moyens d’incitation, en l’adaptant aux caractéristiques nationales.
Antimicrobial resistance (AMR) is a public health problem worldwide. As antibiotic (AB) use is one of the drivers of AMR, the Council of the European Union adopted in 2001 a recommendation on the prudent use of antimicrobial agents. To analyze the way Member States (MS) had implemented this recommendation and to approach its efficacy, we performed a survey under the auspices of the European Commission in 2008, completed by a thorough analysis of the legal framework in twelve Member States. In addition, relationships between AB stewardship programmes (ABS) and trends in AB consumption were studied from 2005 to 2009 in 74 voluntary hospitals in Southwestern France. MS had implemented a broad range of activities to improve AB use, but differences were seen namely in evaluation systems. Further analysis in 12 MS highlighted discrepancies regarding the scope of the legal framework, incentives for its enforcement, and means of evaluation. A legal framework regarding surveillance and national organisation seemed in favor of higher citizens’ knowledge and awareness and appeared to be associated with lower increase in fluoroquinolone (FQ) use. In French hospitals, ABS had sharply improved and AB consumption remained stable when adjusted on activity. The presence of an antibiotic advisor combined with provision of training and use of prescriptions with stop-orders…
Advisors/Committee Members: Maurain, Catherine (thesis director).
Subjects/Keywords: Antibiotiques; Cadre juridique; Union européenne; Étude multicentrique; Bon usage; Antibiotic use; Legal framework; European Union; Multicentre survey; Antibiotic stewardship programmes
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APA ·
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MLA ·
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CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dumartin, C. (2010). Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals. (Doctoral Dissertation). Université de Bordeaux Segalen. Retrieved from http://www.theses.fr/2010BOR21744
Chicago Manual of Style (16th Edition):
Dumartin, Catherine. “Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals.” 2010. Doctoral Dissertation, Université de Bordeaux Segalen. Accessed December 10, 2019.
http://www.theses.fr/2010BOR21744.
MLA Handbook (7th Edition):
Dumartin, Catherine. “Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals.” 2010. Web. 10 Dec 2019.
Vancouver:
Dumartin C. Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals. [Internet] [Doctoral dissertation]. Université de Bordeaux Segalen; 2010. [cited 2019 Dec 10].
Available from: http://www.theses.fr/2010BOR21744.
Council of Science Editors:
Dumartin C. Cadre juridique du bon usage des antibiotiques : analyse comparative dans 12 Etats de l’Union européenne et étude de l’impact sur l’utilisation des antibiotiques dans des établissements de santé du Sud-Ouest de la France : Legal framework and guidance on prudent use of antibiotics : comparative analysis in twelve Member States of the European Union and impact on antibiotic use in French south western hospitals. [Doctoral Dissertation]. Université de Bordeaux Segalen; 2010. Available from: http://www.theses.fr/2010BOR21744
Washington State University
12.
[No author].
Disentangling the wicked problem of antibiotic resistance
.
Degree: 2017, Washington State University
URL: http://hdl.handle.net/2376/12954
► Antimicrobial resistance (AMR) is currently an urgent public health concern worldwide. For low-income regions such as sub-Saharan Africa, absence of surveillance data and systematic investigations…
(more)
▼ Antimicrobial resistance (AMR) is currently an urgent public health concern worldwide. For low-income regions such as sub-Saharan Africa, absence of surveillance data and systematic investigations of risk factors prevents clear assessment of the impact that AMR has in these communities. There is also no empirically-based guidance for intervention strategies. In chapter one, we
use PRISMA guidelines to review 116 journal articles from eastern Africa concerning AMR in people and animals, with the aim of understanding the scale of the problem and contributors to the problem. Over the last 40 years, AMR has reportedly increased, with unregulated
antibiotic use invoked to explain the high prevalence of AMR in the region. Nevertheless, we note critical gaps: (i) consistent speculation about the risk factors for AMR without critical examination; (ii) no standardized system of testing and reporting of AMR data; and (iii) lack of community-based studies on AMR in people. Chapter two reports the outcome of two cross-sectional surveys on
antibiotic use in an informal settlement (slum) in Kenya. Results from this survey show that residents generally have limited and inconsistent knowledge of antibiotics, including a perceived effectiveness of antibiotics for colds and flu. Chapter three explores how variation in lab resources and deviations from prescribed laboratory protocols might impact estimates of AMR prevalence. For the set of factors investigated, i.e. culture conditions, sample storage, isolate selection and repeated re-isolation, we observe that subtle variations are unlikely to significantly alter prevalence estimates. In chapter four, we
use a longitudinal study design to examine how sanitation and
antibiotic use impact household- and individual AMR loads in households living within an informal settlement in Kenya. While there is a relationship between reported
antibiotic use and resistance to sulfamethoxazole and trimethoprim in children, most of the variance in the distribution of resistant bacteria is explained by sanitation variables. We conclude that although it is possible to design educational interventions based on our findings (chapter 2), such interventions are not likely to have a significant impact on community-level AMR when sanitation challenges continue to impact these communities (chapter 4).
Advisors/Committee Members: Call, Douglas R (advisor).
Subjects/Keywords: Health sciences;
Public health;
Microbiology;
Antibiotic resistance;
Antibiotic use;
Escherichia coli;
Informal settlements;
Low-income countries;
Sanitation
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APA (6th Edition):
author], [. (2017). Disentangling the wicked problem of antibiotic resistance
. (Thesis). Washington State University. Retrieved from http://hdl.handle.net/2376/12954
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Disentangling the wicked problem of antibiotic resistance
.” 2017. Thesis, Washington State University. Accessed December 10, 2019.
http://hdl.handle.net/2376/12954.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Disentangling the wicked problem of antibiotic resistance
.” 2017. Web. 10 Dec 2019.
Vancouver:
author] [. Disentangling the wicked problem of antibiotic resistance
. [Internet] [Thesis]. Washington State University; 2017. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/2376/12954.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Disentangling the wicked problem of antibiotic resistance
. [Thesis]. Washington State University; 2017. Available from: http://hdl.handle.net/2376/12954
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Dundee
13.
Ansari, Faranak.
Evaluation and management of hospital antibiotic use.
Degree: PhD, 2010, University of Dundee
URL: http://hdl.handle.net/10588/917390eb-a8ea-477a-8cc8-58b6babac813
► Antimicrobials are unique drugs in that they target "infectious" or "transferable" diseases. There is considerable evidence linking increasing antimicrobial use withincreasing resistance. Resistant bacteria do…
(more)
▼ Antimicrobials are unique drugs in that they target "infectious" or "transferable" diseases. There is considerable evidence linking increasing antimicrobial use withincreasing resistance. Resistant bacteria do not know the boundaries, either between countries or within a society between hospital and primary care. Inappropriate prescribing of antimicrobials in hospitals therefore has consequences for whole communities and problems may spread both nationally and internationally. The gathering of reliable measurements of antibiotic use in hospitals employing standardised methods is essential to building an evidence base and highlighting inconsistencies at national and international levels. In this study, after data processing, validating and record linkage, a method forelectronic conversion of drug supply data to the ATC/DDD classification and forlongitudinal analysis was established for Tayside and then for a set of Europeanhospitals. Time series analysis and interrupted time series analysis were described and used for longitudinal surveillance and interventional study of antimicrobial use. This thesis explores issues concerning the evolution and management of hospital antimicrobial use using a wide range of methods. A series of drug utilisation research studies were implemented as the basis of research methods that, in combination of previously described methods, provided novel studies. No single measure can currently capture all of the aspects of hospital antibiotic use. However, a combination of detailed, point prevalence data from individual patients with longitudinal analysis of total consumption can provide meaningful data for comparison between hospitals and for analysis of the relationship between use and outcome. Additionally, there is a need to apply standard processes and novel methods to produce more meaningful surveillances. Longitudinal and point prevalence surveillances together with an explanation ofvariations in hospital characteristics are used to produce a set of coherent measurements of hospital antimicrobial use. Administrative data for longitudinal surveys requires continuous quality control.Whereas drug utilisation researchers and clinicians should target a set of indicators for interventional studies, large studies at national or international level need central data processing by country to identify targets for evaluation and for interventional studies. Support from experts in other fields is needed to address any shortcomings that may be experienced during continuous antibiotic drug utilisation monitoring at national and international levels.
Subjects/Keywords: hospital antibiotic use; antibacterial; antimicrobial resistance; infection control; surveillance; Tayside; drug supply data; drug utilisation
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APA (6th Edition):
Ansari, F. (2010). Evaluation and management of hospital antibiotic use. (Doctoral Dissertation). University of Dundee. Retrieved from http://hdl.handle.net/10588/917390eb-a8ea-477a-8cc8-58b6babac813
Chicago Manual of Style (16th Edition):
Ansari, Faranak. “Evaluation and management of hospital antibiotic use.” 2010. Doctoral Dissertation, University of Dundee. Accessed December 10, 2019.
http://hdl.handle.net/10588/917390eb-a8ea-477a-8cc8-58b6babac813.
MLA Handbook (7th Edition):
Ansari, Faranak. “Evaluation and management of hospital antibiotic use.” 2010. Web. 10 Dec 2019.
Vancouver:
Ansari F. Evaluation and management of hospital antibiotic use. [Internet] [Doctoral dissertation]. University of Dundee; 2010. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10588/917390eb-a8ea-477a-8cc8-58b6babac813.
Council of Science Editors:
Ansari F. Evaluation and management of hospital antibiotic use. [Doctoral Dissertation]. University of Dundee; 2010. Available from: http://hdl.handle.net/10588/917390eb-a8ea-477a-8cc8-58b6babac813
University of Gothenburg / Göteborgs Universitet
14.
Brittain-Long, Robin.
On the Diagnosis and Management of Viral Respiratory Infections.
Degree: 2010, University of Gothenburg / Göteborgs Universitet
URL: http://hdl.handle.net/2077/22184
► Acute respiratory tract infections (ARTIs), are the most common infections in man, and represent a major global health burden. Viruses, most often causing a mild…
(more)
▼ Acute respiratory tract infections (ARTIs), are the most common infections in man, and
represent a major global health burden. Viruses, most often causing a mild and self-limiting
disease, yet with substantial morbidity and high costs for society, mainly cause upper
respiratory tract infections. 70% of all infections in primary care in Sweden are due to ARTIs.
Lower respiratory infections on the other hand constitute the third leading cause of death
worldwide, mainly in children <5 years of age in resource poor settings. Distinguishing virus
from bacteria can be difficult, and often lead to an over-prescription of antibiotics. Modern
molecular based diagnostic methods have increased the possibility of an etiologic diagnosis of
ARTIs significantly. This thesis aims to evaluate the use of a multiplex real time PCR assay
targeting 13 respiratory viruses and two bacteria, from a clinical perspective.
In paper I, a retrospective study of 954 nasopharyngeal samples, the PCR assay, which is
based on automated specimen extraction and multiplex amplification, is described. Detection
rate was 48%. Streamlined testing and cost limitation (€ 33 per sample) along with high
accuracy and prompt result delivery, is key to successful implementation of broad molecular
testing.
Paper II evaluates in a prospective study of 209 adults with ARTI in primary care, and 100
asymptomatic controls, the impact duration of symptoms have on detection rate. Overall
positive yield was 43% in patients and 2% in controls, with a significantly higher detection
rate in patients with < 6 days duration of symptoms (51%) compared to ≥ 7 days (30%,
p<0.01).
Having access to the PCR assay reduced antibiotic prescription rates by 50%, in a prospective
study (paper III) of 426 adults with ARTI. Patients receiving a result within 48 hours were
prescribed antibiotics in 6,8% (n=14) compared to 15.1% (n=33, p<0.01) in the delayed result
group.
The diagnostic yield in paper IV, a retrospective study of 8753 patients of all ages during 36
consecutive months, was significantly higher during winter (54.7%) than in summer (31.1%,
p<0.001), and in children (61.5%) compared with adults (30.5%, p<0.001). Rhinovirus was
the most frequently found virus (32.5%), independent of season, and displayed a high genetic
variability across seasons.
The findings of this thesis support the implementation of similar methods in routine clinical
care.
Subjects/Keywords: Respiratory virus; Respiratory tract infection; Real-time PCR; Multiplex PCR; Antibiotic use
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APA (6th Edition):
Brittain-Long, R. (2010). On the Diagnosis and Management of Viral Respiratory Infections. (Thesis). University of Gothenburg / Göteborgs Universitet. Retrieved from http://hdl.handle.net/2077/22184
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Brittain-Long, Robin. “On the Diagnosis and Management of Viral Respiratory Infections.” 2010. Thesis, University of Gothenburg / Göteborgs Universitet. Accessed December 10, 2019.
http://hdl.handle.net/2077/22184.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Brittain-Long, Robin. “On the Diagnosis and Management of Viral Respiratory Infections.” 2010. Web. 10 Dec 2019.
Vancouver:
Brittain-Long R. On the Diagnosis and Management of Viral Respiratory Infections. [Internet] [Thesis]. University of Gothenburg / Göteborgs Universitet; 2010. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/2077/22184.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Brittain-Long R. On the Diagnosis and Management of Viral Respiratory Infections. [Thesis]. University of Gothenburg / Göteborgs Universitet; 2010. Available from: http://hdl.handle.net/2077/22184
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
The Ohio State University
15.
Walker, William Lindsey.
Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches.
Degree: PhD, Veterinary Preventive Medicine, 2012, The Ohio State University
URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354216604
► The proportion of dairy calves raised on specialized livestock operations, known colloquially as “calf ranches,” has increased over time. However, data about these operations,…
(more)
▼ The proportion of dairy calves raised on
specialized livestock operations, known colloquially as “calf
ranches,” has increased over time. However, data about these
operations, particularly regarding health and mortality, are
lacking. Accordingly, the overall objectives of this body of work
were: 1) to compile data on calf health, mortality, and health
management practices for a sample of calf ranches across the United
States using an established survey methodology and examine risk
factors related to health outcomes in this population and 2) to
examine calf health and mortality with a prospective observational
longitudinal study on a single large calf ranch and examine risk
factors associated with morbidity and mortality in this
population. The first study examined morbidity,
mortality,
antibiotic use, and biosecurity and biocontainment
policies on a convenience sample of calf ranches in the United
States. Calf ranches identified through a membership list, freely
accessible websites, and personal contacts were surveyed according
to a standard methodology. Herd-level health outcomes for calf
ranches rearing preweaned heifer calves only or both preweaned
heifer and bull calves were summarized and related to a number of
potential risk factors with mixed-effects multivariable logistic
regression. Multiple risk factors altered the odds of morbidity and
mortality. Morbidity and mortality were generally similar to
estimates from studies on US dairy
operations. The second study prospectively
examined morbidity and mortality in relation to various risk
factors for dairy heifer calves entering a single large calf ranch.
Over eight months, morbidity, mortality, and demographic data were
collected from the calf ranch’s record keeping system. Serum total
protein concentration (TP) was determined from blood samples taken
approximately 3 days post-arrival. The risk of morbidities and
mortality in relation to source farm, month of arrival, TP, and
antecedent morbidities were modeled for the calves with available
morbidity data using multivariable Poisson regression with robust
errors. The risks of morbidity and mortality were affected by
source, season, TP, and other morbidities. Incidence of morbidities
and mortality were generally similar to reports for dairy
operations. This body of work provides the first
report of basic health metrics,
antibiotic use, and biosecurity and
biocontainment policies representing a larger sample of US calf
ranches. In general, these industry-wide data suggest similar and
occasionally slightly superior calf health when compared to dairy
operations. Several policies were identified at the herd-level that
could improve morbidity and mortality without significant barriers
to implementation. For individual calves, reducing morbidity at an
early age and improving TP could reduce the risk of subsequent
morbidity and mortality. This work further demonstrates that
analyses such as these can be used effectively to examine
morbidity, mortality, and their risk factors on individual calf…
Advisors/Committee Members: Wittum, Thomas E. (Advisor).
Subjects/Keywords: Epidemiology; dairy; calf ranch; morbidity; mortality; risk factors; biosecurity; biocontainment; antibiotic use; epidemiology
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APA (6th Edition):
Walker, W. L. (2012). Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1354216604
Chicago Manual of Style (16th Edition):
Walker, William Lindsey. “Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches.” 2012. Doctoral Dissertation, The Ohio State University. Accessed December 10, 2019.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1354216604.
MLA Handbook (7th Edition):
Walker, William Lindsey. “Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches.” 2012. Web. 10 Dec 2019.
Vancouver:
Walker WL. Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches. [Internet] [Doctoral dissertation]. The Ohio State University; 2012. [cited 2019 Dec 10].
Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354216604.
Council of Science Editors:
Walker WL. Descriptive and Analytical Epidemiology of Morbidity and
Mortality on Calf Ranches. [Doctoral Dissertation]. The Ohio State University; 2012. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1354216604
University of Guelph
16.
Glass, Shiona K.
Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
.
Degree: 2009, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/1997
► Multivariable linear and negative binomial models were produced to assess relationships among socioeconomic and influenza rate data with the use of macrolide and fluoroquinolone antimicrobials…
(more)
▼ Multivariable linear and negative binomial models were produced to assess relationships among socioeconomic and influenza rate data with the use of macrolide and fluoroquinolone antimicrobials by Canadians. Varying results were found both among and between the macrolide and fluoroquinolone groups; however, a pattern of accessibility to care was apparent. Cheaper antimicrobials were used most often in the most disadvantaged populations, and more expensive antimicrobials were used most frequently in advantaged populations. Significant interactions were found between influenza and socioeconomic variables relating to unemployment, education, and degree of poverty in a population. Results suggest that antimicrobials are being prescribed and consumed at inappropriate rates in both disadvantaged and affluent populations in Canada. In order to reduce antimicrobial use and the further development of antimicrobial resistance in Canada, we suggest that responsible antimicrobial stewardship be practiced and promoted by all physicians in community and hospital settings, particularly during the influenza season.
Subjects/Keywords: Influenza;
Fluoroquinolones;
Macrolides;
Epidemiology;
Antibiotic use
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APA (6th Edition):
Glass, S. K. (2009). Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
. (Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/1997
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Glass, Shiona K. “Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
.” 2009. Thesis, University of Guelph. Accessed December 10, 2019.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/1997.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Glass, Shiona K. “Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
.” 2009. Web. 10 Dec 2019.
Vancouver:
Glass SK. Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
. [Internet] [Thesis]. University of Guelph; 2009. [cited 2019 Dec 10].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/1997.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Glass SK. Risk factors for the use of macrolide and fluoroquinolone antimicrobials by human populations in Canada 2000-2006
. [Thesis]. University of Guelph; 2009. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/1997
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
17.
Bevilacqua, Sibylle.
Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France.
Degree: Docteur es, Sciences de la Vie et de la Santé, 2011, Université Henri Poincaré – Nancy I
URL: http://www.theses.fr/2011NAN10076
► L'usage excessif et inapproprié des antibiotiques a été décrit dans le monde entier depuis 25ans, tant en ville qu'à l'hôpital. En plus des effets délétères…
(more)
▼ L'usage excessif et inapproprié des antibiotiques a été décrit dans le monde entier depuis 25ans, tant en ville qu'à l'hôpital. En plus des effets délétères sur les patients l'utilisation abusive des antibiotiques contribue à l'émergence de résistances bactériennes et à l'augmentation des dépenses hospitalières. Dans les années 1990 plusieurs organisations du monde de la santé ont publié des plans et des recommandations visant à contrôler les consommations en antibiotiques afin de limiter la pression de sélection sur les bactéries et d'en diminuer les coûts. Au CHU de Nancy une politique de bon usage des antibiotiques a été instaurée au milieu des années 1990 puis renforcée en 2006, avec une réorganisation complète du mode prescription et de la délivrance des antibiotiques dans tout l'établissement. Une équipe opérationnelle en infectiologie (EOI) composée d'un infectiologue et d'un pharmacien est intervenue dans une partie des services afin d'améliorer la qualité des prescriptions. Pour évaluer l'impact de l'intervention de l'EOI sur les consommations antibiotique et les coûts qui en découlent, une étude contrôlée en cluster avant/après a été réalisée .Nous avons comparé les consommations globale et par classes antibiotiques ainsi que les coûts « avant » et « après » dans 2 groupes (contrôle et intervention).Les résultats ont montré qu'après l'intervention de l'EIO les consommations globales avaient diminué de 34% dans le groupe intervention et de 3% dans le groupe contrôle ( P=0,003). Pour une même activité, la réduction du coût était 14 fois plus élevée dans le groupe intervention. Nous pouvons donc avancer que l'intervention d'une EOI constitue un moyen efficace pour réduire la consommation hospitalière en antibiotiques et les coûts qui en découlent.
Overuse and inappropriate use of antibiotics has been described worldwide for about 25 years, in both community and hospital settings. In addition to its deleterious effect on patients, antibiotic misuse can lead to the emergence of bacterial resistance and increased the cost of hospitalization. Indeed, during the 1990s several organizations published plans to control the costs of antibiotics and limit selective pressure on microorganisms through surveillance and interventions promoting rational use. An antimicrobial policy has been implemented at the University Hospitals of Nancy since the mid-1990s. This antibiotic policy was therefore reinforced the beginning of 2006, changes included complete reorganization of the methods of prescribing and delivering antibiotics in all wards of the University hospitals of Nancy. In addition, an Operational Multidisciplinary Antibiotic Team (OMAT) including an infectious disease physician and a clinical pharmacist was established in some wards. To evaluate the effectiveness of this OMAT, in reducing the hospital antimicrobial consumption and costs a cluster controlled "before-after" study was performed. We compared consumption of antibiotics overall and by therapeutic class and cost savings between "before" and "after" in both…
Advisors/Committee Members: Rabaud, Christian (thesis director), Thilly, Nathalie (thesis director).
Subjects/Keywords: Antibiotique; Politique bon usage antibiotique; Equipe multidisciplinaire; Essai contrôlé cluster; Coût; Antibiotic; Antibiotic use Policy; Cluster controlled trial; Consumption; Cost savings; Stewardship; 615.329
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APA (6th Edition):
Bevilacqua, S. (2011). Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France. (Doctoral Dissertation). Université Henri Poincaré – Nancy I. Retrieved from http://www.theses.fr/2011NAN10076
Chicago Manual of Style (16th Edition):
Bevilacqua, Sibylle. “Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France.” 2011. Doctoral Dissertation, Université Henri Poincaré – Nancy I. Accessed December 10, 2019.
http://www.theses.fr/2011NAN10076.
MLA Handbook (7th Edition):
Bevilacqua, Sibylle. “Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France.” 2011. Web. 10 Dec 2019.
Vancouver:
Bevilacqua S. Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France. [Internet] [Doctoral dissertation]. Université Henri Poincaré – Nancy I; 2011. [cited 2019 Dec 10].
Available from: http://www.theses.fr/2011NAN10076.
Council of Science Editors:
Bevilacqua S. Evaluation de l'impact d'une équipe opérationnelle en infectiologie sur la consommation et le coût des antibiotiques au CHU de Nancy : essai d'intervention contrôlé : Effects of an operational multidisciplinary team on hospital Antibiotic use and cost in France. [Doctoral Dissertation]. Université Henri Poincaré – Nancy I; 2011. Available from: http://www.theses.fr/2011NAN10076
18.
Olvera, Isaac Daniel.
Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production.
Degree: 2016, Texas A&M University
URL: http://hdl.handle.net/1969.1/157852
► Sustainability in agricultural production has become a large point of emphasis for consumers in the United States. Despite pharmaceutical technologies being used to increase production…
(more)
▼ Sustainability in agricultural production has become a large point of emphasis for consumers in the United States. Despite pharmaceutical technologies being used to increase production efficiency and cost effectiveness, their
use remains questioned by the general public, particularly regarding antibiotics within the livestock sector. Therefore, the objectives of this study were to determine the economic effects of a removal of certain technologies from the U.S. beef cattle production system.
A whole system structural econometric model was used to determine effects of: (1) a removal of feed-grade antibiotics as growth-promotant technologies, and (2) the removal of all growth enhancing technologies from the U.S. beef cattle industry as possible future policy. One year after implementation, the loss of feed grade antibiotics is predicted to reduce fed cattle inventories by 270,000 animals and reduce carcass beef by approximately 227.6 million lb. Additionally, beef production and consumption are estimated to decrease by approximately 1% five years post ban. The loss of all growth enhancing technologies predict much larger implications, with one-year post-ban reductions in fed cattle inventories estimated to be 3.1 million animals and a corresponding 2.2 billion lb reduction in carcass beef. At five years post ban, beef production and beef consumption are projected to decrease by 10.5% and 8.2%, respectively while beef imports are projected to increase by 9.1%.
Additionally, an equilibrium displacement model was used to further investigate the effects of a removal of feed-grade antibiotics used to control liver abscesses in U.S. feedlot cattle. In this model the largest first year change, as expected, is within the slaughter cattle sector with a 4.45% reduction in quantities supplied and an 11.13% increase in slaughter cattle price. The 10-year net change for retail beef is estimated to be a 6.31% reduction in total quantity, and a corresponding 1.13 billion lb loss in total beef supplied at the retail level.
The term ?sustainability? in agricultural production is often interpreted to mean natural or free of certain technologies. This study has shown that the removal of technological advances poses a significant economic concern to beef producers and consumers alike.
Advisors/Committee Members: Herring, Andy D (advisor), Mies, William L (committee member), Anderson, David P (committee member), Sawyer, Jason E (committee member).
Subjects/Keywords: antibiotic; sustainability; judicious use; economic; pharmaceutical
…public preference against routine antibiotic use in livestock
production coupled with shrinking… …and recommended a committee be formed to review and evaluate
antibiotic use in human and… …antibiotic resistant bacteria. Alexander et al. (2008) investigated
the use of multiple… …for the Industry #209 aims to reduce
the overall level of antibiotic use in animal… …changes that lead to overall reductions
in antibiotic use (McDonald’s Corporation, 2015…
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APA (6th Edition):
Olvera, I. D. (2016). Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production. (Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/157852
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Olvera, Isaac Daniel. “Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production.” 2016. Thesis, Texas A&M University. Accessed December 10, 2019.
http://hdl.handle.net/1969.1/157852.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Olvera, Isaac Daniel. “Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production.” 2016. Web. 10 Dec 2019.
Vancouver:
Olvera ID. Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production. [Internet] [Thesis]. Texas A&M University; 2016. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/1969.1/157852.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Olvera ID. Economic Implications Associated with Pharmaceutical Technology Bans in U.S. Beef Production. [Thesis]. Texas A&M University; 2016. Available from: http://hdl.handle.net/1969.1/157852
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
19.
Alberda, W.E.
Gives a higher administration of antibiotics a better herd performance in dairy cattle?.
Degree: 2013, Universiteit Utrecht
URL: http://dspace.library.uu.nl:8080/handle/1874/289496
► The reduction in antibiotic use is an important topic in the Netherlands in the last years. The use of antibiotics in dairy cattle is better…
(more)
▼ The reduction in
antibiotic use is an important topic in the Netherlands in the last years. The
use of antibiotics in dairy cattle is better monitored and the farmers and practicing veterinarians are more aware of the importance of the reduction. This study shows the relation between the
use of antibiotics and several herd performance indicators.
Advisors/Committee Members: Werven, T. van.
Subjects/Keywords: herd performance indicators; antibiotic use; aDD/aY
…Antibiotic use
Indicator
The total aDD/aY without the Percentage culled
aDD/aY for dry cow… …the intra mammary antibiotic use (dry cow- and mastitis treatment) and
udder… …antibiotic use of the farmers.
The hypothesis that there is a decrease in aDD/aY in 2012 with… …their antibiotic use in 2012 in comparison with
2011. Whether the reason for this increase… …dead animals in the herd and the total antibiotic use without the antibiotics used for
dry…
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APA (6th Edition):
Alberda, W. E. (2013). Gives a higher administration of antibiotics a better herd performance in dairy cattle?. (Masters Thesis). Universiteit Utrecht. Retrieved from http://dspace.library.uu.nl:8080/handle/1874/289496
Chicago Manual of Style (16th Edition):
Alberda, W E. “Gives a higher administration of antibiotics a better herd performance in dairy cattle?.” 2013. Masters Thesis, Universiteit Utrecht. Accessed December 10, 2019.
http://dspace.library.uu.nl:8080/handle/1874/289496.
MLA Handbook (7th Edition):
Alberda, W E. “Gives a higher administration of antibiotics a better herd performance in dairy cattle?.” 2013. Web. 10 Dec 2019.
Vancouver:
Alberda WE. Gives a higher administration of antibiotics a better herd performance in dairy cattle?. [Internet] [Masters thesis]. Universiteit Utrecht; 2013. [cited 2019 Dec 10].
Available from: http://dspace.library.uu.nl:8080/handle/1874/289496.
Council of Science Editors:
Alberda WE. Gives a higher administration of antibiotics a better herd performance in dairy cattle?. [Masters Thesis]. Universiteit Utrecht; 2013. Available from: http://dspace.library.uu.nl:8080/handle/1874/289496
20.
Παναγάκου, Σωτηρία.
Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ...
Degree: 2011, University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας
URL: http://hdl.handle.net/10442/hedi/28619
► Upper Respiratory Tract Infections (URTIs) are common in children. The cause is usually viral, but parents and paediatricians contribute to inappropriate antibiotic use, promoting antibiotic…
(more)
▼ Upper Respiratory Tract Infections (URTIs) are common in children. The cause is usually viral, but parents and paediatricians contribute to inappropriate antibiotic use, promoting antibiotic resistance. The first objective of the thesis is to prescribe parental beliefs on antibiotic use for children with URTIs, as long as to analyze paediatricians’ prescribing habits towards children that suffer from URTIs, in Greece, a country with high levels of antibiotic use (2nd in Europe) and antibiotic resistance. The second objective is to identify parents’ and paediatricians’ possible risk factors associated to antibiotic misuse in Greece.
Literature review, along with pre – testing yielded a questionnaire designed to assess parents’ and pediatricians’ Knowledge – Attitude – Practices (KAP) - level. A postal survey was set, addressing to the participant parents who consisted of a multistage geographical cluster national sample of 8000 parents, caring for children 5-6 years old, between January and July, 2007. The paediatricians were reached through telephone survey and were selected according to stratified random sampling, nationwide. An estimated satisfactory number of paediatricians to be included in the survey was approximately 10% of paediatricians in Greece (n = 300).
The response rate of the parents was 69% (n = 5312). Islands presented the lowest response rate while in Northern Greece the response rate was the highest. The majority of Greek parents (80%) knew that UTRIs are mostly self-limited. Earache was the commonest reason for which parents expected antibiotics (45%). Greek parents rarely gave antibiotics to their children without medical advice (10%) and they were happy to receive symptomatic therapy if instructed by their physician. Nevertheless, 11.5% of parents reported to regularly (>30%) be advised over the phone to administer antibiotics. Most parents (88%) believed that unnecessary antibiotic use drives antibiotic resistance; however 51.5% was positive that pharmaceutical industries can always produce new antibiotics capable of killing resistant bacteriae. The risk factors of being a father, low education, immigrant status, single parent, having low income, <2 or >3 children, living on the Islands and without experience in recurrent URIs were significantly associated to inadequate knowledge, inappropriate attitudes and wrong practices.
All pediatricians participating in the survey answered the questionnaire. 97% of pediatricians knew that most URTIs are self – limited; nevertheless, they still prescribed antibiotics unnecessarily for various reasons (i.e. 15.5% to prevent a secondary infection, 25.1% because the patient presented a history of recurrent URTIs, 17.5% because the child was about to go on holidays and parents wanted to carry antibiotics just in case). Even though 46.1% believed that more than 30% of parents wish to receive antibiotic treatment when such therapy is not necessary, 45.5% estimated that the rate of pediatricians prescribing antibiotics because parents wanted so, is low. The…
Subjects/Keywords: Χρήση αντιβιοτικών; Λοιμώξεις ανώτερου αναπνευστικού; Παιδιά; Γονείς; Παιδίατροι; Antibiotic use; Children; Paediatricians; Parents; Upper respiratory tract infections
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APA (6th Edition):
Παναγάκου, . . (2011). Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ... (Thesis). University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας. Retrieved from http://hdl.handle.net/10442/hedi/28619
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Παναγάκου, Σωτηρία. “Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ...” 2011. Thesis, University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας. Accessed December 10, 2019.
http://hdl.handle.net/10442/hedi/28619.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Παναγάκου, Σωτηρία. “Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ...” 2011. Web. 10 Dec 2019.
Vancouver:
Παναγάκου . Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ... [Internet] [Thesis]. University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας; 2011. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10442/hedi/28619.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Παναγάκου . Αποτύπωση των γνώσεων, συνηθειών και πρακτικών των παιδίατρων και των γονέων στην Ελλάδα, σχετικά με τη χρήση και κατάχρηση αντιβιοτικών σ... [Thesis]. University of Thessaly (UTH); Πανεπιστήμιο Θεσσαλίας; 2011. Available from: http://hdl.handle.net/10442/hedi/28619
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Arkansas
21.
Pixley, Christopher.
The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production.
Degree: PhD, 2013, University of Arkansas
URL: https://scholarworks.uark.edu/etd/877
► Historically, major driving factors for the animal agriculture industry have been efficiency and profitability. As demand for efficient food production has increased, the industry…
(more)
▼ Historically, major driving factors for the animal agriculture industry have been efficiency and profitability. As demand for efficient food production has increased, the industry has focused research efforts on ways to improve the rearing process. Current market demands are requiring the industry to abandon some of the traditional tools it has used to maximize productivity. However, developing alternative technologies are available which may fill the void. Unfortunately, these alternatives are less well-described and the beneficial impacts they can have are not fully understood. As the animal agriculture industry matures it is becoming evident that consumers will continue to demand methods of production change to increase sustainability, produce safer food, produce food that is perceived to be more natural, and improve welfare of animals. In order to maintain profitability, companies have been very responsive to market pressures. As customers demand a particular product, companies make efforts to fulfill demand, or risk losing market share. The goal of the studies included herein is to determine what impact selected Socially acceptable, non-traditional technologies can have on the efficiencies of poultry production. The first study evaluates suitability of a commercially available direct-fed microbial (DFM) to replace traditional
antibiotic growth promoters (AGP) in broiler feeds. This study indicates that an effective DFM can replace traditional AGP in poultry feeds and also improve growth efficiencies of poultry currently being grown without AGP. A second study evaluates the effects of inclusion of a unique blend of organic acids in the drinking water of turkeys on body weight loss during feed withdrawal and transport periods. The study suggests that by inclusion of this specific organic acid blend in the drinking water prior to harvest, body weight was positively affected in a manner that meaningfully impacts profitability. Taken together, these studies present non-traditional alternatives for implementation by poultry producers in an effort to meet consumer demands, improve welfare, and increase profitability.
Advisors/Committee Members: Billy M. Hargis, Lisa Bielke, Luc Berghman.
Subjects/Keywords: Biological sciences; Antibiotic use; Direct-fed microbials; Growth performance; Poultry production; Probiotics; Agricultural Education; Poultry or Avian Science; Sustainability
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APA (6th Edition):
Pixley, C. (2013). The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production. (Doctoral Dissertation). University of Arkansas. Retrieved from https://scholarworks.uark.edu/etd/877
Chicago Manual of Style (16th Edition):
Pixley, Christopher. “The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production.” 2013. Doctoral Dissertation, University of Arkansas. Accessed December 10, 2019.
https://scholarworks.uark.edu/etd/877.
MLA Handbook (7th Edition):
Pixley, Christopher. “The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production.” 2013. Web. 10 Dec 2019.
Vancouver:
Pixley C. The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production. [Internet] [Doctoral dissertation]. University of Arkansas; 2013. [cited 2019 Dec 10].
Available from: https://scholarworks.uark.edu/etd/877.
Council of Science Editors:
Pixley C. The Use of Non-Traditional Technologies to Improve the Efficiency and Sustainability of Modern Poultry Production. [Doctoral Dissertation]. University of Arkansas; 2013. Available from: https://scholarworks.uark.edu/etd/877
Curtin University of Technology
22.
Angalakuditi, Mallik V.
Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
.
Degree: 2003, Curtin University of Technology
URL: http://hdl.handle.net/20.500.11937/1689
► Objectives: To evaluate the influence of pharmacist interventions on drug and dosage prescribing in pediatric settings. Method: Demographic, clinical, and prescribing data and parents’ measurement…
(more)
▼ Objectives: To evaluate the influence of pharmacist interventions on drug and dosage prescribing in pediatric settings. Method: Demographic, clinical, and prescribing data and parents’ measurement data were evaluated by pre- and post studies including time series studies and control groups. The data was evaluated against Australian Therapeutic Guidelines. Educational intervention strategies were designed and administered and a post-intervention evaluation was conducted. Group comparisons were made using x2 and Student’s t-test statistics. Time series analysis involved multiple linear regression analysis. Results: The major study involved antibiotics and analgesic drugs and dosages in appendectomy in children. Significant improvements occurred in the selection and dosages of prophylactic antibiotics @<0.001) and in subsequent ward antibiotic treatments @<0.001) also showed marked conformity with the guidelines Other pediatric studies involved liquid medication dosing and prescribing accuracy for paracetamol in a developing country where a simple intervention produced very marked improvements @<0.001). An intervention in severe community-acquired pneumonia showed an improvement in the prescription of appropriate drugs @<0.001) and appropriate dosages of paracetamol (p<O.OOl) according to the guidelines. In drug utilisation evaluation of cefiriaxone, flucloxacillin and Liquigesic COB, there was a significant improvement in the dosage prescribing of ceftriaxone and flucloxacillin and no change in Liquigesic COB following the intervention. O f the total, 38/218 (17%) o f the patients received appropriate post-operative antibiotic dosages. 286/368 (78%) of the analgesic prescriptions and 31/218 (14%) of the patients on postoperative antibiotic choice and dosage that were identified as appropriate in tonsillectomy.Conclusion: This study has identified deficiencies related to the prescribing of antibiotics and analgesics in children. There was a varied level of improvement in the drug dosage prescribing of pediatricians following the pharmacist educational intervention. Locally developed guidelines are more likely to be accepted and followed than those developed nationally without local input.
Subjects/Keywords: antibiotic dosage;
antimicrobial use;
pedicatric drug prescription;
pediatric hospitals
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APA (6th Edition):
Angalakuditi, M. V. (2003). Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
. (Thesis). Curtin University of Technology. Retrieved from http://hdl.handle.net/20.500.11937/1689
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Angalakuditi, Mallik V. “Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
.” 2003. Thesis, Curtin University of Technology. Accessed December 10, 2019.
http://hdl.handle.net/20.500.11937/1689.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Angalakuditi, Mallik V. “Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
.” 2003. Web. 10 Dec 2019.
Vancouver:
Angalakuditi MV. Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
. [Internet] [Thesis]. Curtin University of Technology; 2003. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/20.500.11937/1689.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Angalakuditi MV. Evaluation of pharmacist interventions on drug and dosage prescribing in pediatric settings
. [Thesis]. Curtin University of Technology; 2003. Available from: http://hdl.handle.net/20.500.11937/1689
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
University of Dundee
23.
Ansari, Faranak.
Evaluation and management of hospital antibiotic use.
Degree: PhD, 2010, University of Dundee
URL: https://discovery.dundee.ac.uk/en/studentTheses/917390eb-a8ea-477a-8cc8-58b6babac813
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578772
► Antimicrobials are unique drugs in that they target "infectious" or "transferable" diseases. There is considerable evidence linking increasing antimicrobial use withincreasing resistance. Resistant bacteria do…
(more)
▼ Antimicrobials are unique drugs in that they target "infectious" or "transferable" diseases. There is considerable evidence linking increasing antimicrobial use withincreasing resistance. Resistant bacteria do not know the boundaries, either between countries or within a society between hospital and primary care. Inappropriate prescribing of antimicrobials in hospitals therefore has consequences for whole communities and problems may spread both nationally and internationally. The gathering of reliable measurements of antibiotic use in hospitals employing standardised methods is essential to building an evidence base and highlighting inconsistencies at national and international levels. In this study, after data processing, validating and record linkage, a method forelectronic conversion of drug supply data to the ATC/DDD classification and forlongitudinal analysis was established for Tayside and then for a set of Europeanhospitals. Time series analysis and interrupted time series analysis were described and used for longitudinal surveillance and interventional study of antimicrobial use. This thesis explores issues concerning the evolution and management of hospital antimicrobial use using a wide range of methods. A series of drug utilisation research studies were implemented as the basis of research methods that, in combination of previously described methods, provided novel studies. No single measure can currently capture all of the aspects of hospital antibiotic use. However, a combination of detailed, point prevalence data from individual patients with longitudinal analysis of total consumption can provide meaningful data for comparison between hospitals and for analysis of the relationship between use and outcome. Additionally, there is a need to apply standard processes and novel methods to produce more meaningful surveillances. Longitudinal and point prevalence surveillances together with an explanation ofvariations in hospital characteristics are used to produce a set of coherent measurements of hospital antimicrobial use. Administrative data for longitudinal surveys requires continuous quality control.Whereas drug utilisation researchers and clinicians should target a set of indicators for interventional studies, large studies at national or international level need central data processing by country to identify targets for evaluation and for interventional studies. Support from experts in other fields is needed to address any shortcomings that may be experienced during continuous antibiotic drug utilisation monitoring at national and international levels.
Subjects/Keywords: 615; hospital antibiotic use; antibacterial; antimicrobial resistance; infection control; surveillance; Tayside; drug supply data; drug utilisation
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APA (6th Edition):
Ansari, F. (2010). Evaluation and management of hospital antibiotic use. (Doctoral Dissertation). University of Dundee. Retrieved from https://discovery.dundee.ac.uk/en/studentTheses/917390eb-a8ea-477a-8cc8-58b6babac813 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578772
Chicago Manual of Style (16th Edition):
Ansari, Faranak. “Evaluation and management of hospital antibiotic use.” 2010. Doctoral Dissertation, University of Dundee. Accessed December 10, 2019.
https://discovery.dundee.ac.uk/en/studentTheses/917390eb-a8ea-477a-8cc8-58b6babac813 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578772.
MLA Handbook (7th Edition):
Ansari, Faranak. “Evaluation and management of hospital antibiotic use.” 2010. Web. 10 Dec 2019.
Vancouver:
Ansari F. Evaluation and management of hospital antibiotic use. [Internet] [Doctoral dissertation]. University of Dundee; 2010. [cited 2019 Dec 10].
Available from: https://discovery.dundee.ac.uk/en/studentTheses/917390eb-a8ea-477a-8cc8-58b6babac813 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578772.
Council of Science Editors:
Ansari F. Evaluation and management of hospital antibiotic use. [Doctoral Dissertation]. University of Dundee; 2010. Available from: https://discovery.dundee.ac.uk/en/studentTheses/917390eb-a8ea-477a-8cc8-58b6babac813 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578772
University of Guelph
24.
Watters, Mary Ellen Alexandrea.
Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
.
Degree: 2019, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/16101
► Canadian dairy producers have taken a proactive approach to addressing food safety through the Canadian Quality Milk (CQM) program; now known as the Food Safety…
(more)
▼ Canadian dairy producers have taken a proactive approach to addressing food safety through the Canadian Quality Milk (CQM) program; now known as the Food Safety module of proAction. This thesis investigated the CQM program,
antibiotic use, and CQM
antibiotic record quality in Ontario.
A survey was used to understand the experiences of CQM Advisors (n= 99) who administered a voluntary training program available to Ontario dairy producers prior to their first CQM audit. In general, Advisors reported a positive experience and felt training was beneficial to producers.
The Ontario CQM database (n=4,001 herds) was analyzed to evaluate producer performance at first and second audit. Participation in the voluntary training program was high; 88.9% of Ontario dairy producers participated. Success at first validation visit was also high (79.6%). Training was associated with greater odds of producer success at first validation visit. There appeared to be a cohort effect based on audit year as well as variability due to auditor variation. This indicates a need for future research to understand these impacts.
A cross-sectional approach was used to survey Ontario producers’ (n= 101) approaches towards
antibiotic use and mastitis treatment for the milking herd. Dry cow therapy (DCT) was a common preventative approach (89%) with blanket DCT used by most producers (78%). Respondents were divided as to their level of concern about potential changes to
antibiotic regulations.
A convenience sample of 2014 CQM
antibiotic treatment records (n= 71 herds) was evaluated; all herds had been CQM validated. Treatment of mastitis followed by DCT were the most common reasons for
antibiotic administrations in adult dairy cows. Record quality was highly variable by herd. The evidence of missing and inaccurate information in the records indicates a need for either greater scrutiny of records during CQM audits or for more frequent evaluation of records for CQM compliance.
To conclude, the DFO voluntary producer training program was well received and effective. Producer compliance with requirements for
antibiotic treatment records outside of CQM audits was highly variable by herd. Issues with missing information and recording inaccuracies signify that more producer outreach and education is merited.
Advisors/Committee Members: Kelton, David F (advisor).
Subjects/Keywords: Canadian Quality Milk;
proAction;
food safety;
milk quality;
dairy producer education;
veterinarian advisors;
audits;
HACCP;
mastitis;
antibiotic use;
producer records
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APA (6th Edition):
Watters, M. E. A. (2019). Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
. (Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/16101
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Watters, Mary Ellen Alexandrea. “Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
.” 2019. Thesis, University of Guelph. Accessed December 10, 2019.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/16101.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Watters, Mary Ellen Alexandrea. “Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
.” 2019. Web. 10 Dec 2019.
Vancouver:
Watters MEA. Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
. [Internet] [Thesis]. University of Guelph; 2019. [cited 2019 Dec 10].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/16101.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Watters MEA. Towards understanding antibiotic use and producer performance under the Canadian Quality Milk Program
. [Thesis]. University of Guelph; 2019. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/16101
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
Brilhante, Vânia Cristina Ribeiro.
Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará.
Degree: 2011, Universidade Federal do Amazonas
URL: http://tede.ufam.edu.br/handle/tede/4521
► O uso inadequado de antimicrobianos é fator determinante para disseminação da resistência bacteriana. Esta emergência de resistência bacteriana representa, mundialmente, um problema de saúde pública.…
(more)
▼ O uso inadequado de antimicrobianos é fator determinante para disseminação da resistência bacteriana. Esta emergência de resistência bacteriana representa, mundialmente, um problema de saúde pública. Vários países têm usado como estratégias políticas de restrição para tornar o uso mais racional, principalmente em hospitais onde o uso é mais prevalente. O objetivo deste estudo foi avaliar o grau de conhecimento de princípios básicos de antibioticoterapia e do papel da CCIH por médicos no Estado do Pará. Este estudo foi realizado através de questionários respondidos por médicos clínicos, pediatras e cirurgiões, que atuam em urgência e emergência em hospitais de Belém e região metropolitana do Estado do Pará, que possuem atendimento de urgência e emergência no período de Setembro de 2009 a Fevereiro de 2010. Foram respondidos 468 questionários, sendo 235 de médicos clínicos, 120 de médicos pediatras e 113 de médicos cirurgiões. A prescrição de duração de 7 dias correspondeu a 56,9% entre os clínicos, onde antimicrobiano mais prescrito foi a azitromicina (35,7%) e 64% entre os pediatras cujo antimicrobiano mais prescrito foi a amoxicilina. A antibioticoprofilaxia foi de 51,3% durante a indução anestésica, demonstrando que quase a metade, prescrevem inadequadamente a profilaxia. Dos 113 cirurgiões, apenas 30% seguem as orientações da CCIH para a prescrição de antimicrobianos no pós operatório e a cefazolina é o antibiótico mais prescrito (47%), seguido do ceftriaxone (23%). O hemograma influencia na prescrição de antibiótico em 98,4% entre os cirurgiões, 93,6% entre os clínicos e 81,6% entre os pediatras, e a dificuldade de acompanhamento ambulatorial foi fator importante para 286 médicos. Fatores como a pressão da família e volume de atendimentos não mostraram ser influentes na prescrição. A bacteriúria assintomática é tratada por 66% dos clínicos, 50,4% dos cirurgiões e 71,7% dos pediatras, assim como mais de 50% de todas as especialidades tratam os sintomas de disúria e febre, sem confirmação microbiológica de infecção. A padronização de antimicrobianos existe em 83,3% e apenas 24 médicos responderam que a Comissão de
Farmácia e Terapêutica é responsável pela padronização dos antimicrobianos, sendo que 20,4% desconhecem estratégias voltadas para o uso racional em seu hospital. O antimicrobiano mais prescrito entre os pediatras foi a amoxacilina (44%), seguido de azitromicina (31%), entretanto o tempo de prescrição foi inadequado entre os clínicos. As inadequações entre os cirurgiões ocorreram em relação a antibioticoprofilaxia e duração desta. Apenas 30% dos cirurgiões seguem as orientações da CCIH, e a cefazolina é o antibiótico mais prescrito (47%), seguido do ceftriaxone em 23%. Em relação a solicitação de culturas apenas 43% o fazem antes da prescrição. O uso de terapia empírica inapropriada foi encontrado como sendo causa de mortalidade em pacientes com bacteremia originada no trato urinário. O presente estudo tem, entre suas limitações, o fato de basear-se em dados referidos, os quais encerram um considerável…
Advisors/Committee Members: Sousa, Rita Catarina Medeiros, CPF:297.254.702-06, http://lattes.cnpq.br/3560941703812539.
Subjects/Keywords: Antibiótico - Uso terapêutico; Resistência à droga; Resistência microbiana; Antibioticoterapia; Antibiotic - Rational use; Antimicrobial resistance; CIÊNCIAS DA SAÚDE: SAÚDE COLETIVA
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APA ·
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to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Brilhante, V. C. R. (2011). Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from http://tede.ufam.edu.br/handle/tede/4521
Chicago Manual of Style (16th Edition):
Brilhante, Vânia Cristina Ribeiro. “Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará.” 2011. Masters Thesis, Universidade Federal do Amazonas. Accessed December 10, 2019.
http://tede.ufam.edu.br/handle/tede/4521.
MLA Handbook (7th Edition):
Brilhante, Vânia Cristina Ribeiro. “Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará.” 2011. Web. 10 Dec 2019.
Vancouver:
Brilhante VCR. Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2011. [cited 2019 Dec 10].
Available from: http://tede.ufam.edu.br/handle/tede/4521.
Council of Science Editors:
Brilhante VCR. Avaliação do grau de conhecimento dos princípios básicos de antibioticoterapia de médicos que atuam em urgência e emergência no Estado do Pará. [Masters Thesis]. Universidade Federal do Amazonas; 2011. Available from: http://tede.ufam.edu.br/handle/tede/4521
Kaunas University of Medicine
26.
Butkytė,
Vitalija.
Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė.
Degree: Master, Pharmacy, 2007, Kaunas University of Medicine
URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2007~D_20070802.105108-98734
;
► Neracionalus antimikrobinių vaistų (AMV) vartojimas didina mikroorganizmų atsparumą, gydymo kaštus ir hospitalizacijos trukmę. Didėjantis atsparumas AMV yra svarbi visuomenės sveikatos problema. Magistro darbo tikslas -…
(more)
▼ Neracionalus antimikrobinių vaistų (AMV)
vartojimas didina mikroorganizmų atsparumą, gydymo kaštus ir
hospitalizacijos trukmę. Didėjantis atsparumas AMV yra svarbi
visuomenės sveikatos problema. Magistro darbo tikslas - kokybiškai
ir kiekybiškai įvertinti AMV skyrimo KMU klinikose paplitimą bei jo
pokyčius ir atitikimo racionalaus AMV vartojimo rekomendacijoms
ypatumus ir dėsningumus. Tyrimas atliktas naudojant „skersinio
pjūvio“ metodiką. 2007 m. kovo mėnesį vienmomentinio apžvalginio
tyrimo metu (2 savaičių laikotarpyje) atrinktos ir išanalizuotos
pacientų, kurie gauna AMV, ligos istorijos ir paskyrimai 32-iuose
KMU klinikų skyriuose. AMV vartojimas yra racionalus, jei jų
skyrimas atitinka racionalaus AMV vartojimo rekomendacijoms.
Peržiūrėta 1213 paskyrimų, AMV buvo skirti 265 pacientams.
Rekomendacijų neatitiko pusė (54 proc.) visų AMV paskyrimų. Daugiau
kaip pusė (58 proc.) gydymo tikslu skirtų empirinių AMV paskyrimų
vertinti kaip neatitinkantys racionalaus AMV rekomendacijų.
Vertinant AMV skyrimo atitikimą rekomendacijoms atskiruose
skirtingo profilio skyriuose daugiausia neatitikusių paskyrimų
nustatyta chirurginio (74 proc.) ir terapinio (55 proc.) profilio
skyriuose, atitikusių – pediatrinio (71proc.) ir intensyvios
terapijos (60 proc.) profilių skyriuose. Ryšio tarp skyriaus
profilio ir atitikimo rekomendacijoms nenustatyta. (r = 0,5387 , p
= 0,4613, Spearmano koreliacija). Didžiąją dalį neatitinkančių
rekomendacijų paskyrimų atvejų (56,86 proc.) sudarė galimas...
[toliau žr. visą tekstą]
Irrational and excessive use of antibiotics
increases resistance to these preparations. Antimicrobial
resistance is a serious public health problem worldwide. The main
goal of our study was to evaluate and to compare the non-adherence
(NA) to guidelines (NfG) on rational antibiotic therapy and
prophylaxis (ABT/P) in tertiary hospital setting among two years
(2006 and 2007). A cross-sectional study was performed in order to
collect the data for patients receiving prescriptions for
antimicrobial agents in March, 2007. Descriptive and comparative
data were processed and evaluated using Graph Pad Prism 4
statistics program. Rationality of antibiotic therapy was evaluated
according for adherence to published guidelines. A total of 265
(21%) patients recieved antibiotic therapy. 54% of all events were
considered as non-adherent.The majority of NA cases was determined
in the departments of therapeutic profile (55%) and in surgical
profile (74%). The adherent events - in paediatric profile(71%) and
in the intensive therapy profile (60%). No dependence between the
type of profile and adherence to guidelines was determined (r =
0,5387, p = 0,4613, Spearman correlation). The main reasons of NA
were inapropriate dosage (57%) and choice of drug (43% ). NA case
analysis revealed too high dose prescribed in 40/87 (46%) cases,
too low dose 47/87 (54%)cases; too broad spectrum in 28/61 (46%)
cases, too narrow - in 9/61(15%), 2/61 ( 3 %) case as unsafe and
22/61 (36%) cases were related to... [to full
text]
Advisors/Committee Members: Mačiulaitis, Romaldas (Master’s thesis supervisor), Gumbrevičius, Gintautas (Master’s thesis reviewer), Marksienė, Rūta (Master’s degree committee chair), Vainauskas, Paulius (Master’s degree committee member), Janulis, Valdimaras (Master’s degree committee member), Tarasevičius, Eduardas (Master’s degree committee member), Savickas, Arūnas (Master’s degree committee member), Radžiūnas, Raimondas (Master’s degree committee member), Kaduševičius, Edmundas (Master’s degree committee member), Barsteigienė, Zita (Master’s degree session secretary).
Subjects/Keywords: Vaistų
vartojimas; Neracionalus Vaistų
vartojimas;
Antibiotikoterapija; Drug use; Irrational drug
use; Antibiotic
therapy
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APA ·
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APA (6th Edition):
Butkytė,
Vitalija. (2007). Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė. (Masters Thesis). Kaunas University of Medicine. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2007~D_20070802.105108-98734 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Chicago Manual of Style (16th Edition):
Butkytė,
Vitalija. “Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė.” 2007. Masters Thesis, Kaunas University of Medicine. Accessed December 10, 2019.
http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2007~D_20070802.105108-98734 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
MLA Handbook (7th Edition):
Butkytė,
Vitalija. “Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė.” 2007. Web. 10 Dec 2019.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Vancouver:
Butkytė,
Vitalija. Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė. [Internet] [Masters thesis]. Kaunas University of Medicine; 2007. [cited 2019 Dec 10].
Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2007~D_20070802.105108-98734 ;.
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
Council of Science Editors:
Butkytė,
Vitalija. Antimikrobinių vaistų vartojimo palyginamoji bei
probleminių atvejų atitikimo racionalaus vaistų vartojimo
rekomendacijoms analizė. [Masters Thesis]. Kaunas University of Medicine; 2007. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2007~D_20070802.105108-98734 ;
Note: this citation may be lacking information needed for this citation format:
Author name may be incomplete
27.
Ivanovska, V.
Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children.
Degree: 2017, University Utrecht
URL: http://dspace.library.uu.nl/handle/1874/348454
;
URN:NBN:NL:UI:10-1874-348454
;
urn:isbn:978-94-6182-768-5
;
URN:NBN:NL:UI:10-1874-348454
;
http://dspace.library.uu.nl/handle/1874/348454
► Children are not small adults, but rather a distinct and heterogeneous patient group with specific therapeutic needs. Child development entails dynamic processes inherent to growth…
(more)
▼ Children are not small adults, but rather a distinct and heterogeneous patient group with specific therapeutic needs. Child development entails dynamic processes inherent to growth from birth into adulthood, and children face a scope of diseases different than those of adults.Accordingly, safe and effective paediatric pharmacotherapy requires medicines adjusted to the needs, acceptability and preferences (of each subpopulation) of children. Moreover, child-specific antibiotics are one key public health area of interest, due to their potential to fight bacterial infectionsthat are among leading causes of death in early life. Despite recent progress, more work lies ahead, and so the aim of the present thesis was to document advancements with respect to priority medicines for children, and conduct additional research on age-appropriate formulations and
use of antibiotics in children across different settings. The adoption of the EU Paediatric Regulation has lead to a fundamental change of culture, as the incentives and regulatory requirements have induced companies to screen new adult products for their potential paediatric value.Due to the modest impact on high priority and unmet paediatric needs (e.g. oncology, pain, neonatal morbidity), a number of corrective measures have now been taken, so that medicines for children are developed independently from adult indications. We observed shifting trends toward oral solid formulations with a focus on innovative flexible, multiparticulate and dispersiblepreparations. Their advantages include a provision of easy, safe and convenient dose delivery and - in terms of resource-limited settings - superior stability in hot climate zones, easier transport and storage, as well as a reduction in problems with confidentiality and social stigma. However, our research suggests that more age-appropriate antibiotics that facilitate the treatment of childrenexist globally than currently included on the World Health Organization Model List for Essential Medicines for Children. Hence, it is important to create a global platform to provide the information about the benefits, shortcomings and availability of age-appropriate formulations for children, and advocate for their rational
use. Then again, the rational
use of medicines in children has been inadequately studied. Our study on trends in prescribing patterns for acute childhood infections in primary care in developing and transitional countries showed a mixed progress with most of the treatment aspects of infections remaining sub-optimal over time. In high-income countries prescribing is often not rational either, as we found incorrect
use of newer broad spectrum antibioticsand/or inappropriate
use of antibiotics for viral infections. Moreover, we investigated a specific form of irrational
use of antibiotics, self-medication by patients in Macedonia. This entails either getting antibiotics at the pharmacy without a prescription or using leftover antibiotics from previous treatments. We found that interventions had a small effect on…
Advisors/Committee Members: Leufkens, Bert, Mantel - Teeuwisse, Aukje, van Dijk, Liset.
Subjects/Keywords: paediatric pharmacotherapy; paediatric drug development; priority setting; age-appropriate formulations; antibiotic use
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APA ·
Chicago ·
MLA ·
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APA (6th Edition):
Ivanovska, V. (2017). Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children. (Doctoral Dissertation). University Utrecht. Retrieved from http://dspace.library.uu.nl/handle/1874/348454 ; URN:NBN:NL:UI:10-1874-348454 ; urn:isbn:978-94-6182-768-5 ; URN:NBN:NL:UI:10-1874-348454 ; http://dspace.library.uu.nl/handle/1874/348454
Chicago Manual of Style (16th Edition):
Ivanovska, V. “Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children.” 2017. Doctoral Dissertation, University Utrecht. Accessed December 10, 2019.
http://dspace.library.uu.nl/handle/1874/348454 ; URN:NBN:NL:UI:10-1874-348454 ; urn:isbn:978-94-6182-768-5 ; URN:NBN:NL:UI:10-1874-348454 ; http://dspace.library.uu.nl/handle/1874/348454.
MLA Handbook (7th Edition):
Ivanovska, V. “Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children.” 2017. Web. 10 Dec 2019.
Vancouver:
Ivanovska V. Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children. [Internet] [Doctoral dissertation]. University Utrecht; 2017. [cited 2019 Dec 10].
Available from: http://dspace.library.uu.nl/handle/1874/348454 ; URN:NBN:NL:UI:10-1874-348454 ; urn:isbn:978-94-6182-768-5 ; URN:NBN:NL:UI:10-1874-348454 ; http://dspace.library.uu.nl/handle/1874/348454.
Council of Science Editors:
Ivanovska V. Priority medicines for children : Exploring age-appropriate medicines and antibiotic use in children. [Doctoral Dissertation]. University Utrecht; 2017. Available from: http://dspace.library.uu.nl/handle/1874/348454 ; URN:NBN:NL:UI:10-1874-348454 ; urn:isbn:978-94-6182-768-5 ; URN:NBN:NL:UI:10-1874-348454 ; http://dspace.library.uu.nl/handle/1874/348454
28.
Poizat, Axelle.
Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice.
Degree: Docteur es, Economie de la santé animale, 2018, Nantes, Ecole nationale vétérinaire
URL: http://www.theses.fr/2018ONIR109F
► Réduire les usages d’antibiotiques est un des leviers principaux pour contrer l’avancée de l’antibiorésistance qui menace l’efficacité du traitement des maladies bactériennes humaines et animales.…
(more)
▼ Réduire les usages d’antibiotiques est un des leviers principaux pour contrer l’avancée de l’antibiorésistance qui menace l’efficacité du traitement des maladies bactériennes humaines et animales. En filières bovin laitier et jeunes bovins de boucherie, deux maladies de production sont responsables des principaux usages d’antibiotiques, respectivement les mammites et les maladies respiratoires. L’objectif de la thèse a été d’identifier auprès des acteurs des filières des verrous limitant l’amélioration des pratiques la diminution de l’utilisation d’antibiotiques, puis d’identifier des leviers d’action. En élevage de jeunes bovins de boucherie, des entretiens auprès d’acteurs de la filière (éleveurs et responsables) et des enquêtes auprès d’éleveurs ont permis d’identifier que l’organisation de la filière est un des principaux verrous. Cependant, les caractéristiques des systèmes d’exploitations et les compétences des éleveurs constituaient également une potentielle limite. En élevage bovin laitier, des entretiens ont permis de montrer que les perceptions et connaissances des éleveurs semblaient être un des freins majeurs à l’amélioration des pratiques, le système d’exploitation semblant intervenir à la marge. En élevage bovin allaitant, des leviers permettant d’améliorer la coordination entre les acteurs de la chaîne de valeur ont été identifiés. En élevage laitier, un programme innovant de formation et de conseil a été évalué dans le cadre d’une étude d’intervention, montrant une amélioration des connaissances et perceptions des éleveurs sur la prévention et l’utilisation des antibiotiques.
Reducing antibiotic use is one of the main levers to limit the increase of antimicrobial resistance, which threatens the effectiveness of the treatments of human and animal bacterial diseases. In dairy and young beef bull sectors, antibiotics are mainly used to control two production diseases, respectively mastitis and bovine respiratory diseases (BRD). The objective of the thesis was to identify with sectors’ stakeholders’ limitations for the improvement of antibiotic use practices, then to identify levers of action. In the young beef bulls’ sector, interviews with stakeholders and farmers showed that the organization of the value chain, because of its potential influence on BRD risk factors, was one of the main limitation identified. However, the characteristics of farming systems and farmers’ skills were also a potential limitation. In the dairy sector, interviews have shown that farmers’ perceptions and knowledge seemed to be one of the major limitation to the improvement of the practices. The farming system seemed to have only limited influence. In young beef bulls sector, levers to improve coordination between stakeholders in the value chain have been identified. In dairy farming, an innovative training and advising program was evaluated as part of an intervention study, showing an improvement in the knowledge and perceptions of farmers regarding prevention measures and antibiotic use.
Advisors/Committee Members: Fourichon, Christine (thesis director), Bonnet Beaugrand, Florence (thesis director).
Subjects/Keywords: Usage des antibiotiques; Chaine de valeur; Coûts de transaction; Information; Elevage bovin; Formation; Antibiotic use; Value chain; Transaction costs; Information; Cattle farming; Training
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APA ·
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APA (6th Edition):
Poizat, A. (2018). Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice. (Doctoral Dissertation). Nantes, Ecole nationale vétérinaire. Retrieved from http://www.theses.fr/2018ONIR109F
Chicago Manual of Style (16th Edition):
Poizat, Axelle. “Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice.” 2018. Doctoral Dissertation, Nantes, Ecole nationale vétérinaire. Accessed December 10, 2019.
http://www.theses.fr/2018ONIR109F.
MLA Handbook (7th Edition):
Poizat, Axelle. “Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice.” 2018. Web. 10 Dec 2019.
Vancouver:
Poizat A. Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice. [Internet] [Doctoral dissertation]. Nantes, Ecole nationale vétérinaire; 2018. [cited 2019 Dec 10].
Available from: http://www.theses.fr/2018ONIR109F.
Council of Science Editors:
Poizat A. Freins et leviers à une réduction d’utilisation des antibiotiques en élevage bovin liés à l’organisation économique des filières, aux systèmes d’exploitation et au conseil. : Limitation and levers to a reduction of antibiotic use in cattle sector related to the economic organisation of sectors, of farming systems, and of advice. [Doctoral Dissertation]. Nantes, Ecole nationale vétérinaire; 2018. Available from: http://www.theses.fr/2018ONIR109F
29.
Sposeto, Valdinélia Bomfim Barban.
Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos.
Degree: Mestrado, Gastroenterologia Clínica, 2009, University of São Paulo
URL: http://www.teses.usp.br/teses/disponiveis/5/5147/tde-29092009-172840/
;
► INTRODUÇÃO: A realização de procedimentos invasivos e o comprometimento da função hepática têm sido apontados como importantes fatores predisponentes à peritonite bacteriana primária (PBE) em…
(more)
▼ INTRODUÇÃO: A realização de procedimentos invasivos e o comprometimento da função hepática têm sido apontados como importantes fatores predisponentes à peritonite bacteriana primária (PBE) em pacientes cirróticos. Apesar das bactérias gram-negativas ainda serem os agentes mais freqüentemente isolados, a incidência de infecção por bactérias gram positivas tem aumentado. OBJETIVOS: Analisar os fatores de risco para PBE em pacientes cirróticos e relacionar o perfil da flora infectante do líquido ascítico com o uso de antibióticos. MÉTODOS: Estudo retrospectivo de resultados de 1.114 paracenteses realizadas em 348 pacientes no período de 2005 a 2007 no Departamento de Gastroenterologia do Hospital das Clínicas da Universidade de São Paulo. Foram definidos dois grupos: com e sem PBE, segundo resultado da leucometria do líquido ascítico. Os seguintes fatores foram analisados: aspartato aminotransferase (AST); alanina aminotransferase (ALT); bilirrubinas totais; INR; creatinina; uso do propranolol e sua resposta hemodinâmica; antecedente de hemorragia digestiva alta; choque hipovolêmico; tratamento endoscópico de varizes de esôfago; sondagem vesical; cateteres intravenosos; gravidade da doença hepática (escores de Child-Pugh, MELD e MELD-Na); infecções associadas e o perfil da flora infectante, segundo o uso de antibióticos. RESULTADOS: 852 paracenteses em 303 pacientes foram incluídas. A etiologia mais freqüente da cirrose hepática foi hepatite crônica C (25,4%), seguida por álcool (24,1%). O diagnóstico de PBE foi estabelecido em 82 (9,6%) paracenteses, 27 (33%) da forma clássica e 55 (67%) com cultura negativa. No grupo com PBE, observamos níveis mais elevados de bilirrubinas totais e INR (p<0,0001 e p= 0,0016, respectivamente). Não houve diferença entre os grupos, quanto ao uso de betabloqueadores e risco de PBE (32,9% versus 37,3%, p=0,533) e a resposta hemodinâmica ao propranolol (68,2% versus 70%, p=1,00), assim como em relação às seguintes variáveis: hemorragia digestiva alta (6,1% versus 2,5%, p=0,074), escleroterapia endoscópica (2,4% versus 0,8%, p=0,178), sondagem vesical (4,9% versus 2,3%, p=0,138), cateterismo venoso (2,4% versus 1,7%, p= 0,649). O grupo com PBE apresentou maior percentual de pacientes Child C, 51% versus 37%, (p=0,022) e maior frequência de choque hipovolêmico 2,5% versus 0,3% (p=0,0484). Não houve diferença quanto às infecções associadas (p=1,00). No grupo com PBE, as bactérias gram-positivas foram isoladas em 55,6% e as gram-negativas em 44,4% (p=0,3848). Não houve relação entre a presença de infecção por gram positivos e o uso de quinolonas (p=1,00). O aumento de um ponto no escore MELD aumentou o risco de infecção em 1,059 vezes [IC 95% : 1,0266; 1,0930] ou 6%. Não houve diferença no risco de PBE quando analisamos faixas de valores do MELD. O aumento de um ponto no MELD-Na aumentou o risco de infecção em 1,0283 vezes [IC 95%: 1,0073; 1,0497] ou 2,8%. Entretanto, o aumento de um ponto de MELD-Na na faixa entre 6 e 15 aumentou a probabilidade de infecção em 1,3371vezes [IC 95%: 1,0230;…
Advisors/Committee Members: Farias, Alberto Queiroz.
Subjects/Keywords: Antibiotic prophylaxis; Antibioticoprofilaxia; Ascitic fluid/microbiology; Cirrose hepática/complicações; Fatores de risco; Índice de gravidade de doença; Líquido ascítico/microbiologia; Liver cirrhosis/complications; Peritonite; Peritonitis; Risk factors; Severity of illness index; Sódio/uso diagnóstico.; Sodium/diagnostic use
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APA ·
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MLA ·
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APA (6th Edition):
Sposeto, V. B. B. (2009). Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/5/5147/tde-29092009-172840/ ;
Chicago Manual of Style (16th Edition):
Sposeto, Valdinélia Bomfim Barban. “Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos.” 2009. Masters Thesis, University of São Paulo. Accessed December 10, 2019.
http://www.teses.usp.br/teses/disponiveis/5/5147/tde-29092009-172840/ ;.
MLA Handbook (7th Edition):
Sposeto, Valdinélia Bomfim Barban. “Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos.” 2009. Web. 10 Dec 2019.
Vancouver:
Sposeto VBB. Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos. [Internet] [Masters thesis]. University of São Paulo; 2009. [cited 2019 Dec 10].
Available from: http://www.teses.usp.br/teses/disponiveis/5/5147/tde-29092009-172840/ ;.
Council of Science Editors:
Sposeto VBB. Análise dos fatores de risco para peritonite bacteriana espontânea em pacientes cirróticos e do perfil da flora infectante com o uso de antibióticos profiláticos. [Masters Thesis]. University of São Paulo; 2009. Available from: http://www.teses.usp.br/teses/disponiveis/5/5147/tde-29092009-172840/ ;
30.
Νάνου, Χριστίνα.
Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών.
Degree: 2014, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)
URL: http://hdl.handle.net/10442/hedi/39280
► This research studies the nosocomial infections during hospitalization in the neonatal intensive care unit and the risk factors in this environment. More specifically, the main…
(more)
▼ This research studies the nosocomial infections during hospitalization in the neonatal intensive care unit and the risk factors in this environment. More specifically, the main objective of the study is to create a manual of infection control (with guidelines) focused on the problems encountered in the provision of health care units in preterm neonates. The specific aims of the study were the surveillance of nosocomial infections, which held the record of infections and their risk factors, record the use of antibiotics, explore the knowledge of nursing staff, on the prevention of infections in neonatal ICUs, making intervention to employees of the unit based on the results of monitoring, recurrence surveillance of infections and to evaluate the effectiveness of the intervention. The study was conducted in the neonatal intensive care units, of two public hospitals, “Agia Sofia” Children’s Hospital and “Helena Venizelos” Maternity Hospital. The sample of newborns consisted of all neonates that were admitted to the units, during the period of record, total of 474 neonates. The data collection was performed using capture cards infections and antibiotics, questionnaires and lists daily monitoring (checklist). The intervention took place from amphitheater. It was based on the results of the inventory and the methods of prevention of nosocomial infections. Protocols were administered to all attendees, to use, and there were copies in the main compartment of the unit. Statistical analysis of data was performed using the statistical package SPSS. The Scientific Research Committee of each hospital approved the protocol of the survey. The findings of this study indicate that 13.9% (66 of 474 neonates) developed nosocomial infection and colonization is at 7.2%. The most common NI was sepsis (40.9%). Followed by primary bacteremia (34.9%) and upper respiratory infection (13.7%). Microbes detected at significantly higher rates were CoNS, Candida and Klebsiella, at rates of 8.0%, 5.1% and 4.6% respectively. 51.5% of neonates were administered antibiotics empirically. The majority of newborns were either cured (45.5%) or improved (51.5%) and 3.2% of them died. The rates of nosocomial infection were significantly higher in neonates hospitalized in the open unit (24.7%) compared to the closed NICU (8.8%, p<0.001), and to neonates who entered the unit because of prematurity (19.3%, p=0.004). The duration of antibiotic use (antibiotic days) and the duration of hospitalization (patient days), were significantly higher when there was nosocomial infection (p <0,001). The weight of neonates at birth and during the introduction to the unit was significantly lower when there was hospital acquired infection (p <0,001 +). Additionally, the gestational age was significantly lower in infants who presented nosocomial infection (p <0,001). Still, the duration of: intravenous line (p <0,001), Levin (p <0,001), UAC (p = 0,005), CVC (p = 0,012), incubator (p = 0.007) of N-CPAP (p = 0,017) and Hood (p <0,001) were significantly higher when nosocomial…
Subjects/Keywords: Πρόληψη λοιμώξεων; Κατανάλωση αντιβιοτικών; Γνώσεις νοσηλευτικού προσωπικού; Μονάδα εντατικής νοσηλείας νεογνων (ΜΕΝΝ); Παράγοντες κινδύνου; Νοσοκομειακές λοιμώξεις; Κεντρικοί φλεβικοί καθετήρες; Παρέμβαση σε ΜΕΝΝ; Infection control; Antibiotic use; Nurse knowledge; Neonatal intensive care unit (nicu); Risk factors; Nosocomial infections; Control venous catheter (cvc); Intervention in nicu
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APA (6th Edition):
Νάνου, . . (2014). Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών. (Thesis). National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Retrieved from http://hdl.handle.net/10442/hedi/39280
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Νάνου, Χριστίνα. “Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών.” 2014. Thesis, National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Accessed December 10, 2019.
http://hdl.handle.net/10442/hedi/39280.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Νάνου, Χριστίνα. “Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών.” 2014. Web. 10 Dec 2019.
Vancouver:
Νάνου . Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών. [Internet] [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2014. [cited 2019 Dec 10].
Available from: http://hdl.handle.net/10442/hedi/39280.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Νάνου . Εφαρμογή προγράμματος επιτήρησης λοιμώξεων σε μονάδα προώρων νεογνών. [Thesis]. National and Kapodistrian University of Athens; Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ); 2014. Available from: http://hdl.handle.net/10442/hedi/39280
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
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