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You searched for subject:(Alternative toxicity testing). Showing records 1 – 4 of 4 total matches.

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Oregon State University

1. Haggard, Derik. Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish.

Degree: PhD, Toxicology, 2016, Oregon State University

 There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional… (more)

Subjects/Keywords: Zebrafish; Alternative toxicity testing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Haggard, D. (2016). Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/60094

Chicago Manual of Style (16th Edition):

Haggard, Derik. “Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish.” 2016. Doctoral Dissertation, Oregon State University. Accessed July 14, 2020. http://hdl.handle.net/1957/60094.

MLA Handbook (7th Edition):

Haggard, Derik. “Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish.” 2016. Web. 14 Jul 2020.

Vancouver:

Haggard D. Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish. [Internet] [Doctoral dissertation]. Oregon State University; 2016. [cited 2020 Jul 14]. Available from: http://hdl.handle.net/1957/60094.

Council of Science Editors:

Haggard D. Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish. [Doctoral Dissertation]. Oregon State University; 2016. Available from: http://hdl.handle.net/1957/60094


Rutgers University

2. Lee, Serom, 1985-. Classification models for identifying skin sensitizers using in vitro alternatives to animal testing.

Degree: PhD, Biomedical Engineering, 2014, Rutgers University

Allergic contact dermatitis (ACD) is an inflammatory disease that occurs when chemicals known as sensitizers come in contact with the skin. Recent European legislation prohibits… (more)

Subjects/Keywords: Contact dermatitis; Alternative toxicity testing

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Lee, Serom, 1. (2014). Classification models for identifying skin sensitizers using in vitro alternatives to animal testing. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/45328/

Chicago Manual of Style (16th Edition):

Lee, Serom, 1985-. “Classification models for identifying skin sensitizers using in vitro alternatives to animal testing.” 2014. Doctoral Dissertation, Rutgers University. Accessed July 14, 2020. https://rucore.libraries.rutgers.edu/rutgers-lib/45328/.

MLA Handbook (7th Edition):

Lee, Serom, 1985-. “Classification models for identifying skin sensitizers using in vitro alternatives to animal testing.” 2014. Web. 14 Jul 2020.

Vancouver:

Lee, Serom 1. Classification models for identifying skin sensitizers using in vitro alternatives to animal testing. [Internet] [Doctoral dissertation]. Rutgers University; 2014. [cited 2020 Jul 14]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/45328/.

Council of Science Editors:

Lee, Serom 1. Classification models for identifying skin sensitizers using in vitro alternatives to animal testing. [Doctoral Dissertation]. Rutgers University; 2014. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/45328/


Drexel University

3. Eherts, David. In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An).

Degree: 2002, Drexel University

There is a continual need for information concerning the potential for chemicals, if inadvertently splashed into the eyes, to cause effects from irritation to total… (more)

Subjects/Keywords: Alternative toxicity testing; Eye  – Wounds and injuries; Toxicity testing  – In vitro; Bioscience and biotechnology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Eherts, D. (2002). In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An). (Thesis). Drexel University. Retrieved from http://hdl.handle.net/1860/37

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Eherts, David. “In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An).” 2002. Thesis, Drexel University. Accessed July 14, 2020. http://hdl.handle.net/1860/37.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Eherts, David. “In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An).” 2002. Web. 14 Jul 2020.

Vancouver:

Eherts D. In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An). [Internet] [Thesis]. Drexel University; 2002. [cited 2020 Jul 14]. Available from: http://hdl.handle.net/1860/37.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Eherts D. In-vitro tiered approach alternative to live animal testing for determination of ocular or dermal irritation (An). [Thesis]. Drexel University; 2002. Available from: http://hdl.handle.net/1860/37

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Waterloo

4. McCanna, David. Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products.

Degree: 2009, University of Waterloo

 The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing,… (more)

Subjects/Keywords: in vitro; Alternative Methods; alamarBlue; rhodamine; tight junctions; bovine lens; viability; toxicity; mitochondria; mitochondria integrity; benzalkonium chloride; sodium dodecyl sulphate; sodium lauryl sulfate; scanning electron microscopy; Draize; Draize maximal average scores; zonula occludens; cosmetic directive; PETA; humane society; animal league; people for the ethical treatment of animals; interagency coordinating committee on the validation of alternative methods; ICCVAM; ECVAM; JaCVAM; BCOP; bovine cornea; ocular irritants; ocular irritation; ocular toxicity; human corneal epithelial cells; vitro; confocal; confocal microscopy; metabolic activity; optical quality; reactive oxygen species; contact lens; contact lens care solutions; barrier function; microbial keratitis; mulitipurpose solutions; tight junction; cell damage; claudin; ZO-1; occludin; MDCK; Madin; Madin-Darby; canine kidney cells; cornea; human cornea; human corneal epithelium; epithelial cell line; human corneal epithelial cell line; sodium fluorescein; sodium fluorescein permeability; fluorescein permeability; ocular surface; cell monolayer; Araki-Sasaki; cell physiology; risk assessment; safety assessment; ScanTox; scanning laser; lens epithelium; corneal cells; in vitro model; ophthalmic formulations; multiple instillation; back vertex; animal testing; rabbit testing; alternatives to animal testing; cultured bovine lens; toxicity of chemicals; irritation; irritants; laser scanner; organ culture; delayed toxicity; toxins; hydrogen peroxide; cornea toxicity; cornea toxicity models; prediction of human toxicity; no observable adverse effect level; lowest observable adverse effect level; NOAEL; LOAEL; toxicity thresholds; safety factors; cornea; uncertainty factors; preservatives; disinfectants; ophthalmic products; preclinical; preclinical testing; epithelial barrier; drug penetration; clinical confocal microscopy; animal rights; rabbit cornea; human cornea; human clinical effects; toxic; animal rights activist; sensitive measures; toxic effect; toxicity threshold; agar overlay; agar diffusion; agar overlay method; agar diffusion method; cytochrome; cytochrome c; apoptosis; necrotic; apoptotic; necrosis; caspase; rhodamine 123; resazuran; resorufin; cell death; cell viability; metabolic dye; microsomal; microsomal enzymes; cytotoxicity; cytotoxic; cytotoxic effect; MTT; XTT; WST-1; plasma membrane; mitochondrial; mitochondrial morphology; ocular toxicity potential; ocular toxicity; human corneal epithelial; cell line; confocal analysis; corneal epithelium; cell fluorescence; alamarBlue assay; rhodamine dye; animal welfare; toxic injury; degraded mitochondria; epithelial monolayer; disinfectants; membrane integrity; eye toxicity; eye; viability dye; toxicity in humans; human toxicity; effects on the mitochondria; mitochondrial toxicity; in vitro battery; in vitro test battery; ophthalmic eye drop; direct contact; product safety; cytotoxicity potential; molecular; molecular biology; refine reduce replace; sensitivity and relevance; sensitivity; relevance; rabbit ocular irritation test; product development; cytotoxicity models; cytotoxicity alternative methods; replacements for animal testing; three r's; beagle; tiered testing; tiered testing strategy; replacements animal testing; mechanistic toxicity; cornea mitochondria; dose response; threshold

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

McCanna, D. (2009). Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products. (Thesis). University of Waterloo. Retrieved from http://hdl.handle.net/10012/4338

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

McCanna, David. “Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products.” 2009. Thesis, University of Waterloo. Accessed July 14, 2020. http://hdl.handle.net/10012/4338.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

McCanna, David. “Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products.” 2009. Web. 14 Jul 2020.

Vancouver:

McCanna D. Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products. [Internet] [Thesis]. University of Waterloo; 2009. [cited 2020 Jul 14]. Available from: http://hdl.handle.net/10012/4338.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McCanna D. Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products. [Thesis]. University of Waterloo; 2009. Available from: http://hdl.handle.net/10012/4338

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.