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1.
Bedrat, Amina.
G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s.
Degree: Docteur es, Bioinformatique, 2015, Bordeaux
URL: http://www.theses.fr/2015BORD0197
► Des séquences compatibles avec la formation de G4 sont présentes au niveau de certaines régions clés du génome telles que les extrémités des chromosomes, mais…
(more)
▼ Des séquences compatibles avec la formation de G4 sont présentes au niveau de certaines régions clés du génome telles que les extrémités des chromosomes, mais également les régions de commutation de classe des immunoglobulines, les promoteurs de certains gènes dont des oncogènes et des séquences transcrites. Plus de 370 000 cibles potentielles ont été prédites lors des analyses bioinformatiques du génome humain. Cependant, ces prédictions ne sont pas exhaustives étant limitées par la formulation des algorithmes de prédiction utilisés. En effet, les séquences recherchées suivent la formule consensus suivante G3+N(1−7)G3+N(1−7)G3+N(1−7)G3+. Ainsi, en apportant plus de souplesse dans la description du quadruplex nous pourrons identifier et localiser plus de cibles potentielles. C’est pourquoi, nous proposons un nouvel algorithme G4-Hunter qui permettra l’identification la plus exhaustive possible de séquences cibles en prenant en compte la totalité de la région et non plus uniquement la cible potentielle. Par ailleurs, une étude expérimentale à grande échelle (sur une centaine de séquences cibles) a été menée afin de valider et tester la robustesse de G4-Hunter. A l’aide de ce nouvel outil, nous avons pu identifier de nouvelles séquences cibles non identifiées par les approches déjà existantes au sein des génomes humain, HIV et Dictyostelium discoideum.
Biologically relevant G4 DNA structures are formed throughout the genome including immunoglobulin switch regions, promoter sequences and telomeric repeats. They can arise when single-stranded G-rich DNA or RNA sequences are exposed during replication, transcription or recombination. Computational analysis using predictive algorithms suggests that the human genome contains approximately 370 000 potential G4-forming sequences. These predictions are generally limited to the standard G3+N(1−7)G3+N(1−7)G3+N(1−7)G3+ description. However, many stable G4s defy this description and escape this consensus; this is the reason why broadening this description should allow the prediction of more G4 loci. We propose an objective score function, G4- hunter, which predicts G4 folding propensity from a linear nucleic acid sequence. The new method focus on guanines clusters and GC asymmetry, taking into account the whole genomic region rather than individual quadruplexes sequences. In parallel with this computational technique, a large scale in vitro experimental work has also been developed to validate the performance of our algorithm in silico on one hundred of different sequences. G4- hunter exhibits unprecedented accuracy and sensitivity and leads us to reevaluate significantly the number of G4-prone sequences in the human genome. G4-hunter also allowed us to predict potential G4 sequences in HIV and Dictyostelium discoideum, which could not be identified by previous computational methods.
Advisors/Committee Members: Mergny, Jean-Louis (thesis director).
Subjects/Keywords: Bioinformatique; G-quadruplex; ADN; Mitochondrie; Algorithme; Bioinformatic; G-quadruplex; DNA; Mitochondria; Algorithm
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APA (6th Edition):
Bedrat, A. (2015). G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s. (Doctoral Dissertation). Bordeaux. Retrieved from http://www.theses.fr/2015BORD0197
Chicago Manual of Style (16th Edition):
Bedrat, Amina. “G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s.” 2015. Doctoral Dissertation, Bordeaux. Accessed March 07, 2021.
http://www.theses.fr/2015BORD0197.
MLA Handbook (7th Edition):
Bedrat, Amina. “G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s.” 2015. Web. 07 Mar 2021.
Vancouver:
Bedrat A. G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s. [Internet] [Doctoral dissertation]. Bordeaux; 2015. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2015BORD0197.
Council of Science Editors:
Bedrat A. G4-Hunter : un nouvel algorithme pour la prédiction des G-quadruplexes : G4-Hunter : a new algorithm for G-quadruplexes prediction’s. [Doctoral Dissertation]. Bordeaux; 2015. Available from: http://www.theses.fr/2015BORD0197
2.
Boulakirba, Sonia.
Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners.
Degree: Docteur es, Interactions moléculaires et cellulaires, 2015, Nice
URL: http://www.theses.fr/2015NICE4081
► La petite protéine G Arf6 et son facteur d'échange EFA6 sont impliquées dans de nombreux processus cellulaires tels que le remodelage du cytosquelette d’actine, le…
(more)
▼ La petite protéine G Arf6 et son facteur d'échange EFA6 sont impliquées dans de nombreux processus cellulaires tels que le remodelage du cytosquelette d’actine, le transport vésiculaire et mise en place de la polarité épithéliale. Elles jouent également un rôle dans la voie d'endocytose dépendante de la clathrine. Ce travail de thèse nous a permis d’identifier différents mécanismes régulant l’interaction d’EFA6 avec ses différents partenaires. Nous avons pu mettre en évidence une interaction directe entre le domaine N-BAR de l’endophiline et le domaine Sec7 d’EFA6. Nous avons démontré que la courbure membranaire était un facteur régulant cette interaction. EFA6 est capable d’interagir et de recruter l’endophiline sur une membrane lipidique plane alors qu’en présence de vésicules courbées le complexe protéique ne se forme pas. Nous observons également que l’endophiline stimule l’activité d’échange nucléotidique d’EFA6 sur Arf6. Dans un second temps nous avons démontré, dans une étude menée par le Dr Cherfils, que l’activité catalytique d’EFA6 était régulée par une boucle de rétrocontrôle négatif exercée spécifiquement par la protéine Arf6-GTP. Celle-ci induit une diminution de l’activité d’échange d’EFA6 probablement grâce à sa capacité à interagir avec le domaine PH-C-terminal d’EFA6. Enfin, nous avons mis en évidence un repli intramoléculaire entre le domaine C-terminal et le domaine PH d’EFA6 qui semble contrôler l’interaction de cette extrémité C-terminale avec différents partenaires dont la β-arrestine et de façon surprenante la protéine Arf6 dans sa forme inactive.
The small G protein Arf6 and its exchange factor EFA6 control numerous cellular processes such as actin cytoskeleton remodeling, vesicular transport and apico-basal cell polarity. They are also involved in clathrin-dependent endocytosis. In this work we identify different mechanisms by which EFA6 interaction with its various partners is regulated. We have highlighted a direct interaction between the N-BAR domain of endophilin and the Sec7 domain of EFA6. We demonstrated that this interaction is regulated by the membrane curvature. EFA6 interacts and recruits endophilin on a flat lipid membrane whereas the protein complex does not occur in the presence of curved vesicules. We showed that endophilin stimulates the nucleotidic exchange activity of EFA6 on Arf6. Next we demonstrated that the catalytic activity of EFA6 is regulated by a negative feedback loop specifically mediated by the Arf6-GTP. We observed in the presence of Arf6-GTP a decrease of EFA6 catalytic activity and we showed that this effect was due to an interaction between Arf6-GTP and PH-C-terminal domain of EFA6. Finally we demonstrated an intramolecular folding between the C-terminal domain and the PH domain of EFA6 that controls the interaction of the C-terminus domain with various partners including β-arrestin and surprisingly the inactive GDP form of Arf6.
Advisors/Committee Members: Franco, Michel (thesis director).
Subjects/Keywords: Petite protéine G; Facteur d'échange; EFA6; Endocytose; Domaine N-BAR; Small G protein; Exchange factor; EFA6; Endocytosis; N-BAR domain
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Boulakirba, S. (2015). Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners. (Doctoral Dissertation). Nice. Retrieved from http://www.theses.fr/2015NICE4081
Chicago Manual of Style (16th Edition):
Boulakirba, Sonia. “Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners.” 2015. Doctoral Dissertation, Nice. Accessed March 07, 2021.
http://www.theses.fr/2015NICE4081.
MLA Handbook (7th Edition):
Boulakirba, Sonia. “Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners.” 2015. Web. 07 Mar 2021.
Vancouver:
Boulakirba S. Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners. [Internet] [Doctoral dissertation]. Nice; 2015. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2015NICE4081.
Council of Science Editors:
Boulakirba S. Étude des mécanismes moléculaires qui contrôlent l’interaction entre EFA6 et ses partenaires : Molecular mechanisms that control the interaction between EFA6 and its partners. [Doctoral Dissertation]. Nice; 2015. Available from: http://www.theses.fr/2015NICE4081

Université de Grenoble
3.
Rivierre, Yvan.
Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures.
Degree: Docteur es, Informatique, 2013, Université de Grenoble
URL: http://www.theses.fr/2013GRENM089
► Cette thèse s'intéresse à la construction auto-stabilisante de structures couvrantes dans un système réparti. L'auto-stabilisation est un paradigme pour la tolérance aux fautes dans les…
(more)
▼ Cette thèse s'intéresse à la construction auto-stabilisante de structures couvrantes dans un système réparti. L'auto-stabilisation est un paradigme pour la tolérance aux fautes dans les algorithmes répartis. Plus précisément, elle garantit que le système retrouve un comportement correct en temps fini après avoir été perturbé par des fautes transitoires. Notre modèle de système réparti se base sur des mémoires localement partagées pour la communication, des identifiants uniques pour briser les symétries et un ordonnanceur inéquitable, c'est-à-dire le plus faible des ordonnanceurs. Dans la mesure du possible, nous nous imposons d'utiliser les plus faibles hypothèses, afin d'obtenir les constructions les plus générales de structures couvrantes réparties. Nous présentons quatre algorithmes auto-stabilisants originaux pour le k-partitionnement, la construction d'une (f,g)-alliance et l'indexation. Pour chacun de ces problèmes, nous prouvons la correction de nos solutions. De plus, nous analysons leur complexité en temps et en espace à l'aide de preuves formelles et de simulations. Enfin, pour le problème de (f,g)-alliance, nous prenons en compte la notion de convergence sûre qui vient s'ajouter à celle d'auto-stabilisation. Elle garantit d'abord que le comportement du système assure rapidement un minimum de conditions, puis qu'il continue de converger jusqu'à se conformer à une spécification plus exigeante.
This thesis deals with the self-stabilizing construction of spanning structures over a distributed system. Self-stabilization is a paradigm for fault-tolerance in distributed algorithms. It guarantees that the system eventually satisfies its specification after transient faults hit the system. Our model of distributed system assumes locally shared memories for communicating, unique identifiers for symmetry-breaking, and distributed daemon for execution scheduling, that is, the weakest proper daemon. More generally, we aim for the weakest possible assumptions, such as arbitrary topologies, in order to propose the most versatile constructions of distributed spanning structures. We present four original self-stabilizing algorithms achieving k-clustering, (f,g)-alliance construction, and ranking. For every of these problems, we prove the correctness of our solutions. Moreover, we analyze their time and space complexity using formal proofs and simulations. Finally, for the (f,g)-alliance problem, we consider the notion of safe convergence in addition to self-stabilization. It enforces the system to first quickly satisfy a specification that guarantees a minimum of conditions, and then to converge to a more stringent specification.
Advisors/Committee Members: Maraninchi, Florence (thesis director), Carrier, Fabienne (thesis director), Devismes, Stéphane (thesis director).
Subjects/Keywords: Auto-stabilisation; Convergence sûre; Algorithme réparti; K-partitionnement; Ensemble k-dominant; (f; g)-alliance; Self-stabilization; Safe convergence; Distributed algorithm; K-clustering; K-dominating set; (f; g)-alliance; 621
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Rivierre, Y. (2013). Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures. (Doctoral Dissertation). Université de Grenoble. Retrieved from http://www.theses.fr/2013GRENM089
Chicago Manual of Style (16th Edition):
Rivierre, Yvan. “Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures.” 2013. Doctoral Dissertation, Université de Grenoble. Accessed March 07, 2021.
http://www.theses.fr/2013GRENM089.
MLA Handbook (7th Edition):
Rivierre, Yvan. “Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures.” 2013. Web. 07 Mar 2021.
Vancouver:
Rivierre Y. Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures. [Internet] [Doctoral dissertation]. Université de Grenoble; 2013. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2013GRENM089.
Council of Science Editors:
Rivierre Y. Algorithmes auto-stabilisants pour la construction de structures couvrantes réparties : Self-Stabilizing Algorithms for Constructing Distributed Spanning Structures. [Doctoral Dissertation]. Université de Grenoble; 2013. Available from: http://www.theses.fr/2013GRENM089
4.
Younis, Vincent.
Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.
Degree: Care and Social Welfare, 2017, Mälardalen University
URL: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
► Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer…
(more)
▼ Studien undersöker invånare och verksammas upplevelser av ett, enligt en rapport frånunderrättelseenheten, utsatt bostadsområde i Västerås. För att besvara frågeställningen har vigenomfört 14 intervjuer varav 5 var semistrukturerade och resterande var ostrukturerade. Vihar även genomfört 6 observationer, där samtliga var icke deltagande observationer. Dåmålsättningen var att undersöka så förutsättningslöst som möjligt har vi använt oss av BarneyGlasers variant av grundad teori som metodologiskt angreppssätt. Tidigare forskning som vibelyser är delade i tre teman: Segregation, familjestrukturer och sysselsättning. En teorisom är grundad i data presenteras i resultatdelen och beskriver det som sker i Bäckby.Studiens teoretiska referensramar är Erving Goffmans teori om stigma, Howard. S. Beckersteori om avvikande samt Giorgio Agambens teori om undantag och belägring som fungerarsom en komplettering till förståelsen av hur det är i ett utsatt bostadsområde. Slutsatsernavisar att det är en handfull ungdomar som står för oron som sker i Bäckby och dess handlingarmöjliggörs på grund av misslyckade strukturella åtgärder. De förhållanden vi har funnitavgörande för trygghets upplevelse i Bäckby är inte endast att ungdomar behöversysselsättning, utan det behövs även en spridning av människor med utländsk bakgrund blandetniska svenskar och förebyggande åtgärder från externa aktörer.
Subjects/Keywords: u n g d o m a r; b o s t a d s o m r å d e; s y s s e l s ä t t n i n g; s p r i d n i n g; b r o t t; t r y g g h e t; Social Sciences; Samhällsvetenskap
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Younis, V. (2017). Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. (Thesis). Mälardalen University. Retrieved from http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Thesis, Mälardalen University. Accessed March 07, 2021.
http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Younis, Vincent. “Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius.” 2017. Web. 07 Mar 2021.
Vancouver:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Internet] [Thesis]. Mälardalen University; 2017. [cited 2021 Mar 07].
Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Younis V. Att vara välkomen men ändå inte : “Povertyisthemotherofcrime”/MarcusAurelius. [Thesis]. Mälardalen University; 2017. Available from: http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
Zeitoun, Rina.
Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations.
Degree: Docteur es, Informatique, 2015, Université Pierre et Marie Curie – Paris VI
URL: http://www.theses.fr/2015PA066310
► Le 10ème problème de Hilbert, consistant à trouver les solutions entières d'équations polynomiales est un problème crucial en cryptanalyse. Si ce dernier a été prouvé…
(more)
▼ Le 10ème problème de Hilbert, consistant à trouver les solutions entières d'équations polynomiales est un problème crucial en cryptanalyse. Si ce dernier a été prouvé indécidable, Coppersmith publia en 1996 une méthode basée sur la réduction de réseaux permettant de trouver efficacement l'ensemble des petites solutions de certaines équations polynomiales. De nombreuses applications de cette méthode ont vu le jour dans le domaine de la cryptanalyse à clé publique, notamment lorsque le cryptosystème est exécuté sur un système embarqué et qu'une partie de la clé secrète est dévoilée par la réalisation d'attaques physiques sur le dispositif. Dans ce contexte, nous proposons une attaque physique sur le schéma de signature RSA en mode CRT où une application de la méthode de Coppersmith permet de compléter l'information obtenue par l'attaque physique. Nous proposons également un nouvel algorithme déterministe basé sur la méthode de Coppersmith pour factoriser les entiers de la forme N=prqs en temps polynomial lorsque r ou s sont suffisamment grands. Enfin, si les applications de la méthode de Coppersmith sont nombreuses, en pratique, du fait que les réseaux à réduire soient gigantesques, les petites solutions ne peuvent être retrouvées que jusqu'à une borne qui est plus petite que la borne théorique annoncée. Aussi, une autre contribution de cette thèse consiste en la proposition de deux méthodes permettant une accélération du temps d'exécution de l'algorithme de Coppersmith. Lorsque les deux méthodes sont combinées, le nouvel algorithme s'effectue des centaines de fois plus rapidement pour des paramètres typiques, permettant ainsi dans de nombreux cas d'atteindre la borne théorique.
The 10th Hilbert problem, which consists in finding integer solutions to polynomial equations is a crucial problem in cryptanalysis, which has been proven to be undecidable. However, Coppersmith published in 1996 a method based on lattice reduction, which allows to efficiently find all small solutions to some polynomial equations. Many applications of this method have risen in public key cryptanalysis, especially when the cryptosystem is executed on embedded systems and part of the secret key is revealed through physical attacks performed on the device. In this context, we propose in this thesis a physical attack on the RSA signature scheme when the CRT mode is used, where an application of Coppersmith's method allows to complete the information previously obtained by the physical attack. We also propose a new deterministic algorithm based on Coppersmith's method for factoring integers of the form N=prqs in polynomial time, under the condition that r and/or s are sufficiently large. Finally, if the applications of Coppersmith's method are numerous, in practice, since the lattices to be reduced are huge, the small solutions can only be recovered until a bound which is smaller than the enounced theoretical bound. Thus, another contribution of this thesis lies in the proposition of two methods which allow to speed up the execution…
Advisors/Committee Members: Faugère, Jean-Charles (thesis director), Renault, Guénaël (thesis director).
Subjects/Keywords: Algorithme de Coppersmith; Canaux cachés; RSA; LLL; Petites solutions d'équations polynomiales; Factoriser N=p^rq^s; Coppersmith's algorithm; Cryptanalysis; 005.8
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zeitoun, R. (2015). Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations. (Doctoral Dissertation). Université Pierre et Marie Curie – Paris VI. Retrieved from http://www.theses.fr/2015PA066310
Chicago Manual of Style (16th Edition):
Zeitoun, Rina. “Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations.” 2015. Doctoral Dissertation, Université Pierre et Marie Curie – Paris VI. Accessed March 07, 2021.
http://www.theses.fr/2015PA066310.
MLA Handbook (7th Edition):
Zeitoun, Rina. “Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations.” 2015. Web. 07 Mar 2021.
Vancouver:
Zeitoun R. Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations. [Internet] [Doctoral dissertation]. Université Pierre et Marie Curie – Paris VI; 2015. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2015PA066310.
Council of Science Editors:
Zeitoun R. Méthodes algébriques pour l'analyse de sécurité des implantations d'algorithmes cryptographiques : Algebraic methods for security analysis of cryptographic algorithms implementations. [Doctoral Dissertation]. Université Pierre et Marie Curie – Paris VI; 2015. Available from: http://www.theses.fr/2015PA066310

University of New South Wales
6.
Mihova, Marina.
The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian.
Degree: Arts and Media, 2012, University of New South Wales
URL: http://handle.unsw.edu.au/1959.4/53089
;
https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11775/SOURCE01?view=true
► This dissertation examines a terrain of liminality evident in the works of American poet, Lyn Hejinian, whose writing utilizes imagery (ranging from the verbally visual…
(more)
▼ This dissertation examines a terrain of liminality evident in the works of American poet, Lyn Hejinian, whose writing utilizes imagery (ranging from the verbally visual to the explicitly graphic) and a form of Steinian materiality, in the development of a poetic which moves away from the domain of textual representation towards a new form of realism which challenges existing notions of ideology and perception.Drawing upon W.J.T. Mitchell’s theories of visuality and Gaston Bachelard’s theorization of the oneiric qualities of writing, as well as on Freudian dream theory, this thesis maps out how the cross disciplinary dimensions of Hejinian’s poetry, render into being a speaking female
subject.Chapter one provides a contextual framework for Hejinian’s writing, articulating the integral role notions of community and collaboration play in the development of a form of writing situated within a space of in-between. It examines the significant influence of L=A=
N=
G=U=A=
G=E poetics on Hejinian as a key participant of the Language poetry group, while moving at the same time away from a focus on the specifics of her relation to the group, towards an analysis of her broader writing oeuvre as conversant with a phenomenology of dreams and as a development of a multimodal textuality, distinct from the linguistically centered focus of Language poetry. Chapters two and three present a case for the significance of the visual and the material throughout Hejinian’s writing career, as key textual elements in the composition of a language of experience. This experience-focused language, through thematic concern and philosophical inquiry comprises an active representation of female knowledge and desire, which as Hejinian argues throughout her essay “La Faustienne”, has, not by inadvertence but by definition (Hejinian, The Language of Inquiry: 249), been excluded from the narratives of Western history.Chapters five and six illustrate the multimodal female rhetoric developed in preceding chapters as being a language modeled upon a phenomenology of dreaming. Having been the
subject of limited critical attention, Hejinian’s published and unpublished literature on dreams, comprises the central focus of the final two chapters of this dissertation in the development of the chapters’ central claim that, through the composition of a multimodal language, framed and executed through the avenue of experience, Hejinian’s writing project seeks to locate the voice of La Faustienne.
Advisors/Committee Members: Olubas, Brigitta, Arts and Media, Faculty of Arts & Social Sciences, UNSW, Brewster, Anne, Arts and Media, Faculty of Arts & Social Sciences, UNSW.
Subjects/Keywords: Lyn Hejinian; Women's writing; L=A=N=G=U=A=G=E writing; Poetry; Visuality; Materiality; Dreams
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mihova, M. (2012). The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian. (Doctoral Dissertation). University of New South Wales. Retrieved from http://handle.unsw.edu.au/1959.4/53089 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11775/SOURCE01?view=true
Chicago Manual of Style (16th Edition):
Mihova, Marina. “The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian.” 2012. Doctoral Dissertation, University of New South Wales. Accessed March 07, 2021.
http://handle.unsw.edu.au/1959.4/53089 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11775/SOURCE01?view=true.
MLA Handbook (7th Edition):
Mihova, Marina. “The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian.” 2012. Web. 07 Mar 2021.
Vancouver:
Mihova M. The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian. [Internet] [Doctoral dissertation]. University of New South Wales; 2012. [cited 2021 Mar 07].
Available from: http://handle.unsw.edu.au/1959.4/53089 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11775/SOURCE01?view=true.
Council of Science Editors:
Mihova M. The Dream of “La Faustienne” – Reading In-between Language, Image, and Things in the Writing of Lyn Hejinian. [Doctoral Dissertation]. University of New South Wales; 2012. Available from: http://handle.unsw.edu.au/1959.4/53089 ; https://unsworks.unsw.edu.au/fapi/datastream/unsworks:11775/SOURCE01?view=true

Universidade do Rio Grande do Norte
7.
Moreira, Ricardo César de Oliveira.
Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/15438
► This work presents a theoretical and experimental analysis about the properties of microstrip antennas with integrated frequency selective surfaces (Frequency Selective Surface - FSS). The…
(more)
▼ This work presents a theoretical and experimental analysis about the properties
of microstrip antennas with integrated frequency selective surfaces (Frequency
Selective Surface - FSS). The integration occurs through the insertion of the FSS on
ground plane of microstrip patch antenna. This integration aims to improve some
characteristics of the antennas. The FSS using patch-type elements in square unit cells.
Specifically, the simulated results are obtained using the commercial computer
program CST Studio Suite® version 2011. From a standard antenna, designed to operate
in wireless communication systems of IEEE 802.11 a / b /
g /
n the dimensions of the
FSS are varied to obtain an optimization of some antenna parameters such as impedance
matching and selectivity in the operating bands.
After optimization of the investigated parameters are built two prototypes of
microstrip patch antennas with and without the FSS ground plane. Comparisons are
made of the results with the experimental results by 14 ZVB network analyzer from
Rohde & Schwarz ®. The comparison aims to validate the simulations performed and
show the improvements obtained with the FSS in integrated ground plane antenna. In
the construction of prototypes, we used dielectric substrates of the type of Rogers
Corporation RT-3060 with relative permittivity equal to 10.2 and low loss tangent.
Suggestions for continued work are presented
Advisors/Committee Members: Campos, Antônio Luiz Pereira de Siqueira (advisor), CPF:79090095420 (advisor), http://lattes.cnpq.br/1982228057731254 (advisor).
Subjects/Keywords: antenas patch de microfita;
padrões IEEE 802.11 a/b/g/n;
superfícies seletivas em frequência;
integração;
microstrip patch antennas;
IEEE standards 802.11 a / b / g / n;
frequency selective surfaces;
integration
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moreira, R. C. d. O. (2012). Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/15438
Chicago Manual of Style (16th Edition):
Moreira, Ricardo César de Oliveira. “Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.” 2012. Masters Thesis, Universidade do Rio Grande do Norte. Accessed March 07, 2021.
http://repositorio.ufrn.br/handle/123456789/15438.
MLA Handbook (7th Edition):
Moreira, Ricardo César de Oliveira. “Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.” 2012. Web. 07 Mar 2021.
Vancouver:
Moreira RCdO. Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2021 Mar 07].
Available from: http://repositorio.ufrn.br/handle/123456789/15438.
Council of Science Editors:
Moreira RCdO. Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. [Masters Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/15438

Universidade do Rio Grande do Norte
8.
Moreira, Ricardo César de Oliveira.
Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.
Degree: 2012, Universidade do Rio Grande do Norte
URL: http://repositorio.ufrn.br/handle/123456789/15438
► This work presents a theoretical and experimental analysis about the properties of microstrip antennas with integrated frequency selective surfaces (Frequency Selective Surface - FSS). The…
(more)
▼ This work presents a theoretical and experimental analysis about the properties
of microstrip antennas with integrated frequency selective surfaces (Frequency
Selective Surface - FSS). The integration occurs through the insertion of the FSS on
ground plane of microstrip patch antenna. This integration aims to improve some
characteristics of the antennas. The FSS using patch-type elements in square unit cells.
Specifically, the simulated results are obtained using the commercial computer
program CST Studio Suite® version 2011. From a standard antenna, designed to operate
in wireless communication systems of IEEE 802.11 a / b /
g /
n the dimensions of the
FSS are varied to obtain an optimization of some antenna parameters such as impedance
matching and selectivity in the operating bands.
After optimization of the investigated parameters are built two prototypes of
microstrip patch antennas with and without the FSS ground plane. Comparisons are
made of the results with the experimental results by 14 ZVB network analyzer from
Rohde & Schwarz ®. The comparison aims to validate the simulations performed and
show the improvements obtained with the FSS in integrated ground plane antenna. In
the construction of prototypes, we used dielectric substrates of the type of Rogers
Corporation RT-3060 with relative permittivity equal to 10.2 and low loss tangent.
Suggestions for continued work are presented
Advisors/Committee Members: Campos, Antônio Luiz Pereira de Siqueira (advisor), CPF:79090095420 (advisor), http://lattes.cnpq.br/1982228057731254 (advisor).
Subjects/Keywords: antenas patch de microfita;
padrões IEEE 802.11 a/b/g/n;
superfícies seletivas em frequência;
integração;
microstrip patch antennas;
IEEE standards 802.11 a / b / g / n;
frequency selective surfaces;
integration
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moreira, R. C. d. O. (2012). Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. (Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/15438
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Moreira, Ricardo César de Oliveira. “Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.” 2012. Thesis, Universidade do Rio Grande do Norte. Accessed March 07, 2021.
http://repositorio.ufrn.br/handle/123456789/15438.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Moreira, Ricardo César de Oliveira. “Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
.” 2012. Web. 07 Mar 2021.
Vancouver:
Moreira RCdO. Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. [Internet] [Thesis]. Universidade do Rio Grande do Norte; 2012. [cited 2021 Mar 07].
Available from: http://repositorio.ufrn.br/handle/123456789/15438.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Moreira RCdO. Antenas planares integradas com FSSs para aplicações em sistemas de comunicações sem fio
. [Thesis]. Universidade do Rio Grande do Norte; 2012. Available from: http://repositorio.ufrn.br/handle/123456789/15438
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
9.
Dalier, Fabrice.
Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique.
Degree: Docteur es, Chimie, 2016, Paris Sciences et Lettres (ComUE)
URL: http://www.theses.fr/2016PSLEE019
► Des revêtements polymères basés sur la physisorption de copolymères en peigne, dérivés du (Poly-L-Lysine)-g-poly(N Isopropylacrylamide) noté PLL-g-PNIPAM, ont été développés afin de contrôler réversiblement l'adhésion…
(more)
▼ Des revêtements polymères basés sur la physisorption de copolymères en peigne, dérivés du (Poly-L-Lysine)-g-poly(N Isopropylacrylamide) noté PLL-g-PNIPAM, ont été développés afin de contrôler réversiblement l'adhésion cellulaire. La préparation de ces revêtements repose sur l'adsorption spontanée de la poly(lysine) sur la plupart des substrats anioniques usuels en biologie, aisément mis en oeuvre par le non-spécialiste : une simple immersion du substrat dans une solution de PLL-g-PNIPAM donne une monocouche résistante au rinçage et dense en chaines poly(N-Isopropylacrylamide) thermosensibles.L'adsorption de copolymères en peigne dérivés de la PLL et portant des chaînes latérales de natures variées permet d'ajuster à souhait les propriétés du revêtement. Notre attention s'est portée particulièrement sur l'étude de couchesthermosensibles poly(N-Isopropylacrylamide-coligand), où le ligand est soit un groupe biotine, soit un peptide d'adhésion.Une voie de synthèse générique de dérivés PLL-g- PNIPAM est décrite. Elle se fonde sur la polymérisation RAFT du N-acryloxysuccinimide et la post-modification des unités de répétition puis des extrémités de chaînes. Des mesures de la température de transition soluble/insoluble en solution et des caractérisations par AFM et QCM-d de l'extension des chaînes en surface ont permis de démontrer que la transition au sein des revêtements s'opère à une température proche de celle en solution. La stabilité en termes de composition et d'épaisseur des revêtements suite à des cycles de transitions thermiques a été vérifiée. Une étude de l'adsorption de particules décorées par des protéines comme l'avidine a permis de montrer la capacité des couches adsorbée à exposer/masquer la biotine, et à réguler la formation de liaisons spécifiques par simple changement de température. Pour s'assurer de la possibilité d'ajustement du contraste d'accessibilité de ligands, cette étude a été complétée par des mesures sur des couches mixtes contenant des mélanges de chaînes fonctionnelles ou non fonctionnalisées. Enfin, en utilisant un peptide d'adhésion (RGD) comme ligand, il a été montré que l'interaction avec la surface de cellules HeLA peut être réversiblement contrôlée via une variation de température de quelques degrés, moyennant d'optimiser la densité en peptides et la présence de chaînes répulsives en surface.Un control local par stimulation lumineuse a été envisagé. Des poly(N-Isopropylacrylamide) contenant des azobenzenes furent synthétisés mais ne montrent qu'une faible réponse lumineuse.
Polymer coatings based on the physorption of comb-like polymers, (Poly-L-Lysine)-g-poly(NIsopropylacrylamide)derivatives (PLL-g-PNIPAM), have been developed to reversibly modulate specific cell adhesion on demand.This technique of coating relies on the spontaneous adsorption of PLL on typical anionic substrates used in biology: a simple bath application of substrates in solution of PLLg-PNIPAM affords a stable polymer adlayer with dense and thermoresponsive poly(NIsopropylacrylamide) brushes. Adsorption of…
Advisors/Committee Members: Marie-Begue, Emmanuelle (thesis director).
Subjects/Keywords: Revêtement thermo-stimulable; (Poly-LLysine)- g-poly(N-Isopropylacrylamide); Adsorption; Culture cellulaire; Adhésion spécifique; Thermo-responsive coating; (Poly-L-Lysine)- g-poly(N-Isopropylacrylamide); Adsorption; Cell culture; Specific adhesion; 540
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dalier, F. (2016). Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique. (Doctoral Dissertation). Paris Sciences et Lettres (ComUE). Retrieved from http://www.theses.fr/2016PSLEE019
Chicago Manual of Style (16th Edition):
Dalier, Fabrice. “Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique.” 2016. Doctoral Dissertation, Paris Sciences et Lettres (ComUE). Accessed March 07, 2021.
http://www.theses.fr/2016PSLEE019.
MLA Handbook (7th Edition):
Dalier, Fabrice. “Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique.” 2016. Web. 07 Mar 2021.
Vancouver:
Dalier F. Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique. [Internet] [Doctoral dissertation]. Paris Sciences et Lettres (ComUE); 2016. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2016PSLEE019.
Council of Science Editors:
Dalier F. Stimuli-responsive polymer coatings based on (poly-L-Lysine)-g-poly(N-isopropylacrylamide) to control specific cell adhesion : Revêtements polymères stimulables à base de (poly-L-lysine)-g-poly(N-isopropylacrylamide) pour contrôler l’adhésion cellulaire spécifique. [Doctoral Dissertation]. Paris Sciences et Lettres (ComUE); 2016. Available from: http://www.theses.fr/2016PSLEE019

Brno University of Technology
10.
Surynek, Jiří.
Problematika bezdrátových sítí: Wi-Fi Networks Aspects.
Degree: 2018, Brno University of Technology
URL: http://hdl.handle.net/11012/351
This work deals with wireless networks. This work summarizes the techniques used in wireless connection. It deals with the history of wireless connectivity, as well as foreshadowing future trends.
Advisors/Committee Members: Koch, Miloš (advisor), Sklenář,, Pavel (referee).
Subjects/Keywords: Bezdrátové síte; bezdrátové pripojení; Wi-Fi; WiMAX; IEEE 802.11a/b/g/n; IEEE 802.16e.; Key words Wireless networks; wireless connection; Wi-Fi; WiMAX; IEEE 802.11a/b/g/n; IEEE 802.16e.
Record Details
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Surynek, J. (2018). Problematika bezdrátových sítí: Wi-Fi Networks Aspects. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/351
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Surynek, Jiří. “Problematika bezdrátových sítí: Wi-Fi Networks Aspects.” 2018. Thesis, Brno University of Technology. Accessed March 07, 2021.
http://hdl.handle.net/11012/351.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Surynek, Jiří. “Problematika bezdrátových sítí: Wi-Fi Networks Aspects.” 2018. Web. 07 Mar 2021.
Vancouver:
Surynek J. Problematika bezdrátových sítí: Wi-Fi Networks Aspects. [Internet] [Thesis]. Brno University of Technology; 2018. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/11012/351.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Surynek J. Problematika bezdrátových sítí: Wi-Fi Networks Aspects. [Thesis]. Brno University of Technology; 2018. Available from: http://hdl.handle.net/11012/351
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology
11.
Zikmund, Lukáš.
Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies.
Degree: 2019, Brno University of Technology
URL: http://hdl.handle.net/11012/32919
► This master’s thesis is focused on ensuring of Quality of Service (QoS) in wireless network for standards IEEE 802.11 a/b/g/n. First part of this thesis…
(more)
▼ This master’s thesis is focused on ensuring of Quality of Service (QoS) in wireless network for standards IEEE 802.11 a/b/
g/
n. First part of this thesis is focused on the theory of this issue. It covers methods of data transfer in computer networks and individual transfer parameters especially on parameters needed to ensure quality of service. It also describes standards for wireless data transmission and protocols for real time data transmission. The second part is devoted to OPNET modeler and to simulations created on this program. Simulations are focused on real-time data transfer and compare the standards in terms of delay and jitter.
Advisors/Committee Members: Endrle, Pavel (advisor), Škorpil, Vladislav (referee).
Subjects/Keywords: Kvalita služeb; zpoždění; kolísání zpoždění; ztrátovost; IEEE 802.11 a/b/g/n; Quality of Service; latency; jitter; packet loss; IEEE 802.11 a/b/g/n
Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Zikmund, L. (2019). Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/32919
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Zikmund, Lukáš. “Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies.” 2019. Thesis, Brno University of Technology. Accessed March 07, 2021.
http://hdl.handle.net/11012/32919.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Zikmund, Lukáš. “Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies.” 2019. Web. 07 Mar 2021.
Vancouver:
Zikmund L. Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies. [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/11012/32919.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Zikmund L. Optimalizace a analýza závislostí komunikačních služeb na zpoždění: Optimalization and analysis of communication services latency dependencies. [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/32919
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Lorraine
12.
Guigoz, Vincent.
Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production.
Degree: Docteur es, Génie des procédés, des produits et des molécules, 2020, Université de Lorraine
URL: http://www.theses.fr/2020LORR0148
► L’hydrogène est un vecteur énergétique d’avenir en remplacement des hydrocarbures fossiles, à condition d’avoir une production majoritairement décarbonée. L’une des solutions les plus prometteuses pour…
(more)
▼ L’hydrogène est un vecteur énergétique d’avenir en remplacement des hydrocarbures fossiles, à condition d’avoir une production majoritairement décarbonée. L’une des solutions les plus prometteuses pour générer l’hydrogène propre et durable est la décomposition photochimique de l’eau à partir de l’énergie solaire. Dans ce contexte, cette thèse porte sur l’élaboration et l’optimisation d’un photocatalyseur stable et composé d’éléments abondants. LaFeO₃ est un matériau pérovskite semi-conducteur présentant une excellente stabilité chimique et qui absorbe une large part visible du spectre solaire, mais ses propriétés photocatalytiques sont limitées par un faible transport des électrons. Pour améliorer son activité, une hétérostructure associant LaFeO₃ à g-C₃N₄ a été formée. g-C₃N₄ est un semi-conducteur organique 2D avec des propriétés optiques, structurelles et électroniques exceptionnelles. Leur association a permis d’augmenter significativement l’activité photocatalytique par une amélioration de la séparation et du transfert des porteurs de charge. Deux méthodes de production de H₂ ont été étudiées : par photocatalyse (PC) et photoélectrocatalyse (PEC). Les photoélectrodes du dispositif PEC ont été élaborées par pulvérisation cathodique magnétron et les nanoparticules dispersées en solution du dispositif PC ont été synthétisées par voie sol-gel. L’insertion d’une couche de g-C₃N4, déposée par spin-coating, sous le film de LaFeO₃ a permis pour la première fois de former cette hétérojonction en films minces, tandis que l’association par sonication des particules de LaFeO₃ et g-C₃N₄ a permis la création de l’hétérojonction en photocatalyseurs dispersés. L’influence de la composition des photoélectrodes a également été étudiée dans le cas de films non-stœchiométriques et par insertion d’éléments métalliques additionnels.
Hydrogen is a promising energy carrier for replacing fossil fuels, under the conduction of having a mainly low carbon production. One of the most promising solution to generate clean and durable hydrogen is water splitting from solar energy. This manuscript focuses on the development and optimization of an abundant and stable photocatalyst. LaFeO₃ is a perovskite semi-conductor material showing and excellent chemical stability and that absorbs a large part in the visible spectra, although a low electron transfer limits its photocatalytic properties. To improve its activity, a heterostructure associating LaFeO₃ with g-C₃N₄ was realised. g-C₃N₄ is an organic semi-conductor with outstanding optical, structural, and electronic properties. Their association led to a significant increase in the photocatalytic activity by an increase in the separation and transfer of charge carriers. Two methods for H₂ production were studied: photocalysis (PC) and photoelectrocatalysis (PEC). Photoelectrodes of PEC dispositive were elaborated by magnetron sputtering and nanoparticles dispersed in solution of PC dispositive were synthesised using sol-gel. The insertion of a layer of g-C₃N₄, deposited by spin coating, below…
Advisors/Committee Members: Schneider, Raphaël (thesis director), Gries, Thomas (thesis director).
Subjects/Keywords: Photo(électro)catalyse; Photo-dissociation; Hydrogène; LaFeO₃; G-C₃N₄; Photo(electro)catalysis; Water-splitting; Hydrogen; LaFeO₃; G-C₃N₄; 541.35; 541.395; 621.381 52
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Guigoz, V. (2020). Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production. (Doctoral Dissertation). Université de Lorraine. Retrieved from http://www.theses.fr/2020LORR0148
Chicago Manual of Style (16th Edition):
Guigoz, Vincent. “Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production.” 2020. Doctoral Dissertation, Université de Lorraine. Accessed March 07, 2021.
http://www.theses.fr/2020LORR0148.
MLA Handbook (7th Edition):
Guigoz, Vincent. “Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production.” 2020. Web. 07 Mar 2021.
Vancouver:
Guigoz V. Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production. [Internet] [Doctoral dissertation]. Université de Lorraine; 2020. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2020LORR0148.
Council of Science Editors:
Guigoz V. Photocatalyseurs hétérostructurés LaFeO₃/g-C₃N₄ pour la production d’hydrogène : LaFeO₃/g-C₃N₄ heterostructured photocatalysts for hydrogen production. [Doctoral Dissertation]. Université de Lorraine; 2020. Available from: http://www.theses.fr/2020LORR0148

University of California – Riverside
13.
Schacht, Patrick Carl.
Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses.
Degree: Genetics, Genomics and Bioinformatics, 2013, University of California – Riverside
URL: http://www.escholarship.org/uc/item/4f17s6gm
► RIC8 plays a critical role in the regulation of G protein signaling. In this study, a specific chemical inhibitor of the RIC8-GNA-1 interaction is identified.…
(more)
▼ RIC8 plays a critical role in the regulation of G protein signaling. In this study, a specific chemical inhibitor of the RIC8-GNA-1 interaction is identified. In addition to disrupting the interaction in vitro, compound F2342-0045 elicits many of the defects associated with loss of ric8 or gna-1. A suppressor screen identified a novel suppressor of delta-ric8, predicted to be a ham-5 mutant by mapping and sequencing. Suppressors of delta-ric8, delta-pde-1 and delta-rgs-1, were also identified by crosses with G protein related mutants further implicating RIC8 in G&alpha and cAMP regulation. Systematic mutagenesis of the RIC8 protein revealed multiple structure-function relationships. The N-terminus of the protein is essential for binding to GNA-1, while the C-terminus is dispensable for this action. Mutations of conserved residues along the front face of the C-terminus generally inhibit the GEF activity of the RIC8 protein towards GNA-1 and GNA-3 alike, while mutations in the central third of the protein have less effect on GEF activity. Residues that cluster together on the top face of the C-terminus show varied but potent effects, either inhibiting or enhancing GEF activity by 50% or more. These data combine to suggest that the N-terminus of RIC8 is involved in binding of G&alpha proteins, while the C-terminus is involved in GEF activity.
Subjects/Keywords: Genetics; Bioinformatics; Biochemistry; Chemical Genomics; GEF; G protein; N. crassa; Neurospora; RIC8
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Schacht, P. C. (2013). Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses. (Thesis). University of California – Riverside. Retrieved from http://www.escholarship.org/uc/item/4f17s6gm
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Schacht, Patrick Carl. “Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses.” 2013. Thesis, University of California – Riverside. Accessed March 07, 2021.
http://www.escholarship.org/uc/item/4f17s6gm.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Schacht, Patrick Carl. “Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses.” 2013. Web. 07 Mar 2021.
Vancouver:
Schacht PC. Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses. [Internet] [Thesis]. University of California – Riverside; 2013. [cited 2021 Mar 07].
Available from: http://www.escholarship.org/uc/item/4f17s6gm.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Schacht PC. Characterization of the Non-Receptor GEF, RIC8 with Genetic, Chemical, and Biochemical Analyses. [Thesis]. University of California – Riverside; 2013. Available from: http://www.escholarship.org/uc/item/4f17s6gm
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of New Orleans
14.
Komati, Rajesh.
Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs.
Degree: PhD, Chemistry, 2014, University of New Orleans
URL: https://scholarworks.uno.edu/td/1818
► Telomeres are nucleoprotein complexes found at the ends of linear eukaryotic chromosomes. Telomeres consist of a short sequence of repetitive double stranded DNA, TTAGGG…
(more)
▼ Telomeres are nucleoprotein complexes found at the ends of linear eukaryotic chromosomes. Telomeres consist of a short sequence of repetitive double stranded DNA, TTAGGG repeats in humans (and all mammals), and a complex of 6 proteins, termed the shelterin complex. The length of the telomeres varies greatly between species, from approximately 300 base pairs in yeast to many 10-15 kilo bases in humans, because of the end replication problem this length get shorten with each cell division and ultimately leads to cell death. However the immortal eukaryotic cells and some transformed human cells over come this incomplete end replication problem with the use of enzyme called Telomerase. Telomerase is a ribonucleoprotein enzyme that adds a specific DNA sequence repeats (TTAGGG) to the 3¢ end of DNA strands in the telomere regions. However from the telomerase activity studies, it was concluded that telomerase is active in almost 90% of human cancers but not in normal somatic tissues. Finally, the low or transient expression of telomerase in normal tissues, including normal stem cells, and the generally longer telomeres in normal cells versus tumor cells provide a degree of tumor specificity to telomerase-based drugs and reduce the probability of toxicity to normal tissue. All of these factors suggest that cancer drugs based on telomerase might have a broad therapeutic window.
This dissertation focusing on the synthesis of acridine derivatives that have the capability to inhibit the enzyme telomerase. Several
N-acridyl maleimide (NAM),
N-acridyl succinimide (NAS) and
N-acridyl phthalimide (NAP) derivatives have been synthesized and evaluated for their anti cancer activity against various cancer cell lines. While synthesizing acridine derivatives it was required to form the C-
N bonds at various stages. Developed a copper-nicotinic acid complex, which catalyzes the coupling of aryl halides with
N-formyl amines and cyclic imides to form C-
N bond. Explored Cu (II) catalyzed formation of C-
N bond by coupling aryl halides with various
N-nucleophiles such as formamide,
N,N-dimethyl formamide,
N-formyl amines and various cyclic imides.
Advisors/Committee Members: Prof. Branko S. Jursic.
Subjects/Keywords: Cancer, Acridine Derivatives, G-Quadruplex, Copper, C-N bond; Medicinal-Pharmaceutical Chemistry; Organic Chemistry
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Komati, R. (2014). Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs. (Doctoral Dissertation). University of New Orleans. Retrieved from https://scholarworks.uno.edu/td/1818
Chicago Manual of Style (16th Edition):
Komati, Rajesh. “Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs.” 2014. Doctoral Dissertation, University of New Orleans. Accessed March 07, 2021.
https://scholarworks.uno.edu/td/1818.
MLA Handbook (7th Edition):
Komati, Rajesh. “Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs.” 2014. Web. 07 Mar 2021.
Vancouver:
Komati R. Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs. [Internet] [Doctoral dissertation]. University of New Orleans; 2014. [cited 2021 Mar 07].
Available from: https://scholarworks.uno.edu/td/1818.
Council of Science Editors:
Komati R. Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs. [Doctoral Dissertation]. University of New Orleans; 2014. Available from: https://scholarworks.uno.edu/td/1818

Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)
15.
Paspalakis, Antonios.
Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη.
Degree: 2019, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ)
URL: http://hdl.handle.net/10442/hedi/45533
► The corpus of literal texts of Pentzikis is special due to the fact that it has a lot of intertextual references and relies heavily on…
(more)
▼ The corpus of literal texts of Pentzikis is special due to the fact that it has a lot of intertextual references and relies heavily on the literary and/or cultural tradition that is referring to. These references are the subject of our dissertation. We first look into the theoretical tradition of the semantically problematic term of intertextual reference and then decide critically on which term and theory to use. We then move forward and propose a model of interpretation of any intertextual reference, which we use at many cases in Pentzikis work. At the third part, we will use this model to analyze thoroughly his intertextual references at his work, Mother Thessaloniki. At the end of the dissertation as an add on we analyze special theoretical topics of the intertextual reference and we then provide a catalog with all the intertextual references of Pentzikis.
To πεντζικικό κείμενο εμφανίζει την ιδιαιτερότητα να έχει πάρα πολλές διακειμενικές αναφορές και άρα βασίζεται σε μεγάλο βαθμό από την λογοτεχνική ή πολιτισμική παράδοση στην οποία παραπέμπει. Αυτές οι αναφορές είναι και το υλικό το οποίο επεξεργαστήκαμε στην εργασία μας. Πρώτα μελετάμε την θεωρητική παράδοση του εννοιολογικά προβληματικού όρου της διακειμενικής αναφοράς και προσπαθούμε να κατασκευάσουμε τα θεωρητικά μας εργαλεία. Στη συνέχεια, και ως προϊόν μετά-ανάλυσης, προχωρούμε σε μια πρόταση ενός ερμηνευτικού μοντέλου της εκάστοτε διακειμενικής αναφοράς, την οποία και θα εφαρμόσουμε δειγματοληπτικά στο έργο του Πεντζίκη. Στο τρίτο κεφάλαιο θα την εφαρμόσουμε συνολικά στη συλλογή πεζογραφημάτων Μητέρα Θεσσαλονίκη. Στο πρώτο μέρος του επιμέτρου θέτουμε ειδικότερα θέματα της θεωρίας για τη διακειμενική αναφορά, ενώ στο δεύτερο έχουμε αποδελτιωμένες τις διακειμενικές αναφορές του Πεντζίκη, οι οποίες ειδικά θα μπορούσαν να λειτουργήσουν ως ένα είδος υπομνηματισμού του συνόλου του έργου του.
Subjects/Keywords: Διακειμενικότητα; Διακειμενική αναφορά; Πεντζίκης, Ν. Γ.; Intertextuality; Pentzikis, N. G.; Intertextual reference; Allusion
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Paspalakis, A. (2019). Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη. (Thesis). Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Retrieved from http://hdl.handle.net/10442/hedi/45533
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Paspalakis, Antonios. “Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη.” 2019. Thesis, Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ). Accessed March 07, 2021.
http://hdl.handle.net/10442/hedi/45533.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Paspalakis, Antonios. “Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη.” 2019. Web. 07 Mar 2021.
Vancouver:
Paspalakis A. Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη. [Internet] [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 2019. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/10442/hedi/45533.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Paspalakis A. Ν.Γ. Πεντζίκης: η τέχνη της διακειμενικής αναφοράς: το βέβαιο διακειμενικό υπόστρωμα στο έργο του και ένα ερμηνευτικό μοντέλο της διακειμενικής αναφοράς με εφαρμογή στο Μητέρα Θεσσαλονίκη. [Thesis]. Aristotle University Of Thessaloniki (AUTH); Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (ΑΠΘ); 2019. Available from: http://hdl.handle.net/10442/hedi/45533
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
16.
Siblini, Wissam.
Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals.
Degree: Docteur es, Informatique, 2018, Nantes
URL: http://www.theses.fr/2018NANT4083
► Stimulé par des applications comme l’annotation de documents ou d’images, l’apprentissage multi-label a connu un fort développement cette dernière décennie. Mais les algorithmes classiques se…
(more)
▼ Stimulé par des applications comme l’annotation de documents ou d’images, l’apprentissage multi-label a connu un fort développement cette dernière décennie. Mais les algorithmes classiques se heurtent aux nouveaux volumes des données multi-label extrême (XML) où le nombre de labels peut atteindre le million. Cette thèse explore trois directions pour aborder la complexité en temps et en mémoire du problème : la réduction de dimension multi-label, les astuces d’optimisation et d’implémentation et le découpage arborescent. Elle propose d’unifier les approches de réduction à travers une typologie et deux formulations génériques et d’identifier des plus performantes avec une méta-analyse originale des résultats de la littérature. Une nouvelle approche est développée pour analyser l’apport du couplage entre le problème de réduction et celui de classification. Pour réduire la complexité mémoire en maintenant les capacités prédictives, nous proposons également un algorithme d’estimation des plus grands paramètres utiles d’un modèle classique de régression one-vs-rest qui suit une stratégie inspirée de l’analyse de données en flux. Enfin, nous présentons un nouvel algorithme CRAFTML qui apprend un ensemble d’arbres de décision diversifiés. Chaque arbre effectue une réduction aléatoire conjointe des espaces d’attributs et de labels et implémente un partitionnement récursif très rapide. CRAFTML est plus performant que les autres méthodes arborescentes XML et compétitif avec les meilleures méthodes qui nécessitent des supercalculateurs. Les apports de la thèse sont complétés par la présentation d’un outil logiciel VIPE développé avec Orange Labs pour l’analyse d’opinions multi-label.
Stimulated by many applications such as documents or images annotation, multilabel learning have gained a strong interest during the last decade. But, standard algorithms cannot cope with the volumes of the recent extreme multi-label data (XML) where the number of labels can reach millions. This thesis explores three directions to address the complexity in time and memory of the problem: multi-label dimension reduction, optimization and implementation tricks, and tree-based methods. It proposes to unify the reduction approaches through a typology and two generic formulations and to identify the most efficient ones with an original meta-analysis of the results of the literature. A new approach is developed to analyze the interest of coupling the reduction problem and the classification problem. To reduce the memory complexity of a classical one-vs-rest regression model while maintaining its predictive performances, we also propose an algorithm for estimating the largest useful parameters that follows a strategy inspired by data stream analysis. Finally, we present a new algorithm called CRAFTML that learns an ensemble of diversified decision trees. Each tree performs a joint random reduction of the feature and the label spaces and implements a very fast recursive partitioning strategy. CRAFTML performs better than other XML tree-based methods and…
Advisors/Committee Members: Kuntz-Cosperec, Pascale (thesis director), Meyer, Frank (thesis director).
Subjects/Keywords: Algorithme CraftML
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Siblini, W. (2018). Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals. (Doctoral Dissertation). Nantes. Retrieved from http://www.theses.fr/2018NANT4083
Chicago Manual of Style (16th Edition):
Siblini, Wissam. “Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals.” 2018. Doctoral Dissertation, Nantes. Accessed March 07, 2021.
http://www.theses.fr/2018NANT4083.
MLA Handbook (7th Edition):
Siblini, Wissam. “Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals.” 2018. Web. 07 Mar 2021.
Vancouver:
Siblini W. Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals. [Internet] [Doctoral dissertation]. Nantes; 2018. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2018NANT4083.
Council of Science Editors:
Siblini W. Apprentissage multi label extrême : comparaisons d'approches et nouvelles propositions : Extreme multi-label learning : comparisons of approaches and new proposals. [Doctoral Dissertation]. Nantes; 2018. Available from: http://www.theses.fr/2018NANT4083

Université de Neuchâtel
17.
Straubhaar, Régis.
Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces.
Degree: 2013, Université de Neuchâtel
URL: http://doc.rero.ch/record/32642
► Le spectre de l'opérateur de Laplace-Dirichlet défini sur un domaine borné d'une surface lisse et complète est une suite strictement positive, croissante, tendant vers l'infini.…
(more)
▼ Le spectre de l'opérateur de Laplace-Dirichlet défini
sur un domaine borné d'une surface lisse et complète est une suite
strictement positive, croissante, tendant vers l'infini. Le but de
cette thèse est d'approcher les premières valeurs propres de cet
opérateur de manière numérique à l'aide d'une méthode d'éléments
finis, puis de considérer le problème d'optimisation suivant: quel
est le domaine qui minimise la <i>k</i>-ème valeur
propre parmi tous les domaines d'aire donnée, et que vaut cette
valeur propre? Ce dernier trouve son origine dans les théorèmes de
Faber-Krahn et Krahn-Szegö, qui règlent le cas de la première et de
la deuxième valeur propre d'un domaine de l'espace euclidien. Des
méthodes en optimisation de forme ont été élaborées pour proposer
des domaines candidats à être solution pour des valeurs propres
plus élevées ainsi que pour d'autres surfaces sous-jacentes comme
la sphère et l'espace hyperbolique. Cela a donné lieu à des
observations sur la comparaison de valeurs propres associées à des
domaines sur différentes surfaces. Le problème du placement d'un
obstacle circulaire à l'intérieur d'une boule afin de maximiser les
premières valeurs propres est aussi abordé dans cette
thèse.
Advisors/Committee Members: Olivier (Dir.), Bruno (Codir.).
Subjects/Keywords: Algorithme d'Uzawa
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Straubhaar, R. (2013). Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces. (Thesis). Université de Neuchâtel. Retrieved from http://doc.rero.ch/record/32642
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Straubhaar, Régis. “Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces.” 2013. Thesis, Université de Neuchâtel. Accessed March 07, 2021.
http://doc.rero.ch/record/32642.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Straubhaar, Régis. “Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces.” 2013. Web. 07 Mar 2021.
Vancouver:
Straubhaar R. Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces. [Internet] [Thesis]. Université de Neuchâtel; 2013. [cited 2021 Mar 07].
Available from: http://doc.rero.ch/record/32642.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Straubhaar R. Numerical optimization of Dirichlet-Laplace eigenvalues on
domains in surfaces. [Thesis]. Université de Neuchâtel; 2013. Available from: http://doc.rero.ch/record/32642
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
18.
Erbin, Harold.
Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity.
Degree: Docteur es, Physique, 2015, Université Pierre et Marie Curie – Paris VI
URL: http://www.theses.fr/2015PA066367
► La solution des équations d'Einstein–Maxwell décrivant le trou noir le plus général a été découverte par Plebański et Demiański en 1976. Cette thèse accomplit plusieurs…
(more)
▼ La solution des équations d'Einstein–Maxwell décrivant le trou noir le plus général a été découverte par Plebański et Demiański en 1976. Cette thèse accomplit plusieurs étapes en vue d'intégrer une généralisation de cette solution en supergravité jaugée N = 2. Le contenu bosonique de cette dernière comprend la métrique assortie de champs de jauge et de deux types de champs scalaires (appelés scalaires-vecteurs et hyperscalaires); cela implique qu'il est beaucoup plus compliqué de trouver une solution générale et l'on doit se restreindre à des classes particulières de solutions ou bien utiliser des algorithmes pour générer des solutions.Dans la première partie de cette thèse nous approchons ce problème grâce à la première stratégie en nous restreignant aux solutions BPS.Dans un premier temps nous étudions les jaugeages abéliens qui impliquent les hyperscalaires afin de comprendre quelles sont les conditions nécessaires pour obtenir des vides N = 2 adS4 ainsi que des géométries de proche-horizon associées à des trous noirs statiques.Par la suite nous décrivons une solution générale et analytique pour des trous noirs (extrémaux) 1/4-BPS qui possèdent une masse, une charge de NUT, des charges dyoniques et des champs scalaires non-triviaux dans le contexte de la supergravité N = 2 jaugée à la Fayet–Iliopoulos.Dans la seconde partie nous obtenons une extension de l'algorithme de Janis-Newman afin de prendre en compte tous les champs bosoniques de spin inférieur à 2, les horizons topologiques et le cas des autres dimensions.Ainsi cela met à disposition tous les outils nécessaires pour appliquer cet algorithme à la supergravité (jaugée ou non).
The most general black hole solution of Einstein–Maxwell theory has been discovered by Plebański and Demiański in 1976.This thesis provides several steps towards generalizing this solution by embedding it into N = 2 gauged supergravity.The (bosonic fields of the) latter consists in the metric together with gauge fields and two kinds of scalar fields (vector scalars and hyperscalars); as a consequence finding a general solution is involved and one needs to focus on specific subclasses of solutions or to rely on solution generating algorithms. In the first part of the thesis we approach the problem using the first strategy: we restrict our attention to BPS solutions, relying on a symplectic covariant formalism. First we study the possible Abelian gaugings involving the hyperscalars in order to understand which are the necessary conditions for obtaining N = 2 adS4 vacua and near-horizon geometries associated to the asymptotics of static black holes.A preliminary step is to obtain covariant expressions for the Killing vectors of symmetric special quaternionic-Kähler manifolds. Then we describe a general analytic solutions for 1/4-BPS (extremal) black holes with mass, NUT, dyonic charges and running scalars in N = 2 Fayet–Iliopoulos gauged supergravity with a symmetric very special Kähler manifold. In the second part we provide an extension of the Janis–Newman algorithm to all bosonic…
Advisors/Committee Members: Halmagyi, Nick (thesis director).
Subjects/Keywords: Trou noir; Algorithme Janis-Newman; Supergravité n=2; Trou noir en rotation; Espace taub-Nut; Trou noir bps; Black hole; Janis-Newman algorithm; 530
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Erbin, H. (2015). Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity. (Doctoral Dissertation). Université Pierre et Marie Curie – Paris VI. Retrieved from http://www.theses.fr/2015PA066367
Chicago Manual of Style (16th Edition):
Erbin, Harold. “Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity.” 2015. Doctoral Dissertation, Université Pierre et Marie Curie – Paris VI. Accessed March 07, 2021.
http://www.theses.fr/2015PA066367.
MLA Handbook (7th Edition):
Erbin, Harold. “Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity.” 2015. Web. 07 Mar 2021.
Vancouver:
Erbin H. Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity. [Internet] [Doctoral dissertation]. Université Pierre et Marie Curie – Paris VI; 2015. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2015PA066367.
Council of Science Editors:
Erbin H. Trous noirs en supergravité N = 2 : Black holes in N = 2 supergravity. [Doctoral Dissertation]. Université Pierre et Marie Curie – Paris VI; 2015. Available from: http://www.theses.fr/2015PA066367

Texas A&M University
19.
Them, Theodore.
Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age.
Degree: MS, Oceanography, 2012, Texas A&M University
URL: http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11593
► Abrupt, millennial-scale climate oscillations, known as Dansgaard-Oeschger (D-O) cycles, characterized the climate system during the last ice age. Proxy evidence suggests these climate oscillations resulted…
(more)
▼ Abrupt, millennial-scale climate oscillations, known as Dansgaard-Oeschger (D-O) cycles, characterized the climate system during the last ice age. Proxy evidence suggests these climate oscillations resulted in global-scale reorganizations in the hydrological cycle. For this study, Mg/Ca-paleothermometry and stable isotope measurements were combined on the planktonic foraminifera Globigerinoides ruber (white variety) from Florida Straits sediment core KNR166-2 JPC26 (24*19.61'
N, 83*15.14'W; 546 m depth) to reconstruct a high-resolution record of sea surface temperature and delta18OSW (a proxy for upper water column salinity) during Marine Isotope Stages 2 and 3 from 20-35.45 ka BP. As additional proxies for upper water column salinity change, Ba/Ca ratios in
G. ruber were also measured to determine the relative contribution of local riverine input on the delta18OSW record and a faunal abundance count record of the planktonic foraminifera
N. dutertrei abundance was developed. These results show that rapid upper water column salinity changes occurred across D-O events in the Florida Straits, coeval with climate change in the high-latitude North Atlantic. Furthermore, the
G. ruber Ba/Ca record suggests that riverine-derived meltwater from the Gulf of Mexico did not significantly impact surface salinity in the Florida current, calling into question the role of Mississippi River discharge on Atlantic Meridional Overturning Circulation (AMOC) during MIS 2 and 3. Instead, the most likely cause of MIS 2 and 3 salinity changes in the Florida Straits were variations in the strength and position of the Intertropical Convergence Zone. Finally, the timing of surface salinity change was compared with the benthic delta18OC record from the same core. A recent study showed that benthic delta18OC changes on the Florida Margin can be combined with contemporaneous records from the Bahamas Margin to reconstruct Florida Current transport related to AMOC variability. These results show that atmospheric circulation changes lead AMOC changes on the transition out of cold stadial events, suggesting the trigger for these abrupt climate events may reside in the tropics rather than in the high-latitude North Atlantic as previously thought.
Advisors/Committee Members: Schmidt, Matthew W. (advisor), Slowey, Niall C. (committee member), Marcantonio, Franco (committee member).
Subjects/Keywords: Mg/Ca thermometry; G. ruber; N. dutertrei; Paleoclimate; Dansgaard-Oeschger event; ITCZ; Tropical SSS; Tropical SST
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Them, T. (2012). Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11593
Chicago Manual of Style (16th Edition):
Them, Theodore. “Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age.” 2012. Masters Thesis, Texas A&M University. Accessed March 07, 2021.
http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11593.
MLA Handbook (7th Edition):
Them, Theodore. “Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age.” 2012. Web. 07 Mar 2021.
Vancouver:
Them T. Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age. [Internet] [Masters thesis]. Texas A&M University; 2012. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11593.
Council of Science Editors:
Them T. Tropical North Atlantic Hydrologic Cycle Variability in the Florida Straits During the Last Ice Age. [Masters Thesis]. Texas A&M University; 2012. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2012-08-11593

University of Debrecen
20.
Kovács, József.
Call Centerek Matematikai Modellezése
.
Degree: DE – TEK – Informatikai Kar, 2009, University of Debrecen
URL: http://hdl.handle.net/2437/87268
► A dolgozatom során a bevezető részen túl, négy különböző, de egymással szoros kapcsolatban álló rendszert elemző forrásokat rendeztem egyfajta logikai sorrendbe. Először az Erlang C…
(more)
▼ A dolgozatom sorá
n a bevezető részen túl, négy különböző, de egymással szoros kapcsolatban álló rendszert elemző forrásokat rendeztem egyfajta logikai sorrendbe. Először az Erlang C került vizsgálódásom középpontjába, amely egyszerűségével igen vonzó a Call Center menedzserek számára. Gyors és pontos algoritmus létezik a kiszámítására, ahogy azt a 6.5. fejezetben idézett forrás is részletesen leírja.
Azonban ennek a rendszernek komoly hiányosságai is vannak. Az első abból adódik, hogy lényegében azonos híváskezelési időkkel számol, amely nem mindig tartható feltételezés. Ennek feloldását tárgyalja a 7. fejezet, amely aszimptotikus közelítést ad a késleltetési valószínűségekre, és ebből származtatja a TSF-et és az ASA-t. Ebben a fejezetben lesz említve először az iparágban létező három létszámfeltöltési rezsim, irányvonal, amelyeket egyenként Hatékonysá
g-, Minőségvezéreltnek és Racionalizáltnak nevezünk. Fontos megemlíteni a szolgáltatási gradienst, amelynek szinten tartása a Racionalizált rezsim feladata, a többletlétszám (Hatékonyságvezérelt) vagy a rendszerkihasználtsá
g (Minőségvezérelt) szinten tartásával szemben. A Racionalizált rezsimnek ugyanez a célja az Erlang A rendszerben is.
Az Erlang C végtelen türelmet feltételez a hívók részéről, ami torlódás eseté
n 0 TSF-hez vezet, amelynek elkerülése a Call Center menedzserek elsődleges célja. A trunk vonalak számának beállíthatósága olyan eszköz a kezükben, amellyel elkerülhetik az ilyen túlterhelési szituációkat, cserébe lesznek olyan ügyfelek, amelyek foglalt jelzést kapnak. Ezeknek az arányáról ad pontos képet a 8. fejezet, amely az Erlang B modellel kapcsolatos forrásokból építkezik. Szinté
n létezik pontos és valós időben számoló algoritmus, amelyet a 8.3. fejezet ismertet olyan rendszerekben, ahol a késleltetés valószínűsége nulla ( 0 sorhossz ).
Végül az Erlang A modellel foglalkozó cikkekből merít a diplomamunkám. A 9.2 fejezetben látható egy olyan modell, amelyben a különböző, eddig tárgyalt rendszerek ismérvei vannak összegyúrva. Ebben a modellben, ha valaki szabad az
N számú kiszolgáló közül, akkor a hívás azonnal oda lesz irányítva. Ha nem, de
N < B ahol B a trunk vonalak száma, és van szabad hely a maximálisan B -
N hosszúságú sorban, akkor ott kell várakoznia a hívásnak. A többi foglalt jelzést kap. Ebben a fejezetben a középponti kérdés a sorban várakozó ügyfelek sorsa, amelyek az Erlang C modellel ellentétben nem várnak örökké, hanem feladják a hívást. Ennek az aránynak a számítása fontos hatékonyságmutató ebben a modellben az ASA, TSF és a Blokkolási valószínűsé
g mellett, amelyeket már az előző modellekben is említettünk. Létezik pontos számítás, amelyeket a források segítségével a 9.3. fejezetben említek. De ennél is fontosabbak a közelítések, amelyek kellően pontosak, és valós időben számolhatóak (9.5.3. fejezet ). A 9. fejezetet a többletlétszám kiszámítására adott gyakorlati szabályok ismertetésével fejezem be a 3 különböző rezsimben.
Advisors/Committee Members: Sztrik, János (advisor).
Subjects/Keywords: Erlang A;
Erlang B;
Erlang C;
M/G/N
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kovács, J. (2009). Call Centerek Matematikai Modellezése
. (Thesis). University of Debrecen. Retrieved from http://hdl.handle.net/2437/87268
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kovács, József. “Call Centerek Matematikai Modellezése
.” 2009. Thesis, University of Debrecen. Accessed March 07, 2021.
http://hdl.handle.net/2437/87268.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kovács, József. “Call Centerek Matematikai Modellezése
.” 2009. Web. 07 Mar 2021.
Vancouver:
Kovács J. Call Centerek Matematikai Modellezése
. [Internet] [Thesis]. University of Debrecen; 2009. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/2437/87268.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kovács J. Call Centerek Matematikai Modellezése
. [Thesis]. University of Debrecen; 2009. Available from: http://hdl.handle.net/2437/87268
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Edith Cowan University
21.
Yu, Xinwei.
Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes.
Degree: 2019, Edith Cowan University
URL: https://ro.ecu.edu.au/theses/2199
► Objective Type 2 diabetes (T2DM) is a complicated and comprehensive disease that has many metabolic facets with its prevalence increasing with age. The inflammation hypothesis…
(more)
▼ Objective
Type 2 diabetes (T2DM) is a complicated and comprehensive disease that has many metabolic facets with its prevalence increasing with age. The inflammation hypothesis of T2DM was proposed at the American Diabetes Association’s 65th scientific session and subsequently validated in many studies. Immunoglobulin G (IgG) is the main component of antibody formation after a secondary immune response and therefore plays an important role in the inflammation cascade and in the occurrence and development of age-related diseases. N-glycosylation, an important post-translation modifying process, significantly affects the function of IgG molecules, including complement activation, receptor binding properties, molecular recognition and aggregation. As T2DM is a low-grade chronic inflammatory disease and IgG N-glycosylation involves in the inflammation cascade, we hypothesised that IgG N-glycans could be involved in pathophysiological process of T2DM. To provide clues to the molecular mechanisms, and screen intervention targets and search for early diagnosis marker of T2DM, we conducted an observational study analyzing the correlation between IgG N-glycans and aging, and age-related disease, T2DM.
Methods
This was an observational study with a longitudinal design. A community-based cohort in Beijing Xicheng district was established in 2012, and 701 participants aged from 23 to 68 (244 males and 457 females) were recruited. Demographic information and 39 clinical traits (7 anthropometric, 10 biochemical and 22 hematological) were collected and blood was sampled for plasma IgG N-glycans analysis using Ultra performance liquid chromatography (UPLC). From the glycan testing platform, 22 IgG N-glycan chromatographic peaks were detected and then 22 basic glycan traits (GP1-2, GP4-19, GP21-24) were calculated from the relative contributions of individual peaks to the total IgG N-glyans. Based on the 22 basic glycan traits, 54 derived glycan traits (17 derived basic glycan traits, 14 neutral glycan traits, 23 derived neutral glycan traits) were obtained for describing glycosylation character in details.
In 2014, a sample of 516 participants (160 males and 356 females), aged from 26 to 66 were re-investigated in a follow-up survey and the same clinical traits were collected. All the statistical analyses were performed with SPSS 23.0 and R programming language software. All reported P values were 2-sided and PN-glycans and level of fasting plasma glucose (FPG). Canonical correlation analysis (CAA) was used to determine the integrate correlation between IgG N-glycans and clinical traits. The potential of IgG N-glycans to be a biomarker of T2DM was analysed by receiver-operating characteristic (ROC) curve and decision tree methods. The relationship between IgG N-glycan traits and age was assessed by all-subsets regression, binominal regression and permutation test.
Results
1. Screening IgG N-Glycans for type 2 diabetes
A sample of 701 participants from the baseline survey was categorised into three groups according to their FPG…
Subjects/Keywords: Immunoglobulin G N-glycans; type 2 diabetes; fasting plasma glucose; age; biomarker; Han Chinese population; Diagnosis
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Yu, X. (2019). Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes. (Thesis). Edith Cowan University. Retrieved from https://ro.ecu.edu.au/theses/2199
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Yu, Xinwei. “Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes.” 2019. Thesis, Edith Cowan University. Accessed March 07, 2021.
https://ro.ecu.edu.au/theses/2199.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Yu, Xinwei. “Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes.” 2019. Web. 07 Mar 2021.
Vancouver:
Yu X. Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes. [Internet] [Thesis]. Edith Cowan University; 2019. [cited 2021 Mar 07].
Available from: https://ro.ecu.edu.au/theses/2199.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Yu X. Immunoglobulin G N-glycan profiling as a risk stratification biomarker for type 2 diabetes. [Thesis]. Edith Cowan University; 2019. Available from: https://ro.ecu.edu.au/theses/2199
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Cambridge
22.
Watson, Joanna.
Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.
Degree: PhD, 2017, University of Cambridge
URL: https://www.repository.cam.ac.uk/handle/1810/268520
► Cdc42 is a member of the Rho family of small GTPases, which, together with its homologues RhoA and Rac1, controls a multitude of cellular functions…
(more)
▼ Cdc42 is a member of the Rho family of small GTPases, which, together with its homologues RhoA and Rac1, controls a multitude of cellular functions via the actin cytoskeleton. Cdc42 exerts its effects on the cytoskeleton via effector proteins of the Wiskott-Aldrich Syndrome (WASP) family and the Transducer of Cdc42-dependent Actin assembly (TOCA) family. The WASP family and their activation by Cdc42 have been thoroughly studied in vitro and are well understood. Conversely, understanding of the TOCA family remains limited by a lack of biochemical, biophysical and structural insight.
An investigation of the TOCA1-Cdc42 interaction is described here, revealing a relatively low affinity interaction with a dissociation constant in the micromolar range. This is 10-100x weaker than other Rho-effector interactions and suggests that TOCA1 must first be co-localised with Cdc42 to achieve stable binding in vivo. The solution NMR structure of the Cdc42 binding HR1 domain of TOCA1 provides the first structural data on this protein and reveals some interesting structural features that may relate to binding affinity and specificity. A structural model of the Cdc42-HR1 complex provides further insight into differential specificities and affinities of GTPase-effector interactions. NMR and actin polymerisation assays provide insight into the pathway of Cdc42/TOCA1/WASP-dependent actin assembly, suggesting unidirectional displacement of TOCA1 by N-WASP. A comparison of the Cdc42- TOCA1 model with an NMR structure of Cdc42 in complex with the GTPase binding domain of WASP reveals a possible mechanism by which an ‘effector handover’ from TOCA1 to N-WASP could take place.
Small GTPases such as Cdc42 are lipid modified and membrane anchored via their C- termini in vivo, so in vitro studies using truncated, unmodified GTPases are limited in their biological interpretation. This project also aimed to develop methods to study full length and membrane-anchored GTPases in vitro. Lipid modified protein was produced, which showed a weak affinity for liposomes, and so structural studies of membrane anchored protein are within reach. Further method development is now required to achieve stable membrane anchoring of lipid modified GTPases for detailed NMR studies.
Subjects/Keywords: Cdc42; NMR; TOCA1; NWASP; WASL; N-WASP; GTPase; G protein; HR1 domain; Filopodia; Endocytosis; Cell signalling; Protein protein interaction
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Watson, J. (2017). Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. (Doctoral Dissertation). University of Cambridge. Retrieved from https://www.repository.cam.ac.uk/handle/1810/268520
Chicago Manual of Style (16th Edition):
Watson, Joanna. “Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.” 2017. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://www.repository.cam.ac.uk/handle/1810/268520.
MLA Handbook (7th Edition):
Watson, Joanna. “Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.” 2017. Web. 07 Mar 2021.
Vancouver:
Watson J. Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. [Internet] [Doctoral dissertation]. University of Cambridge; 2017. [cited 2021 Mar 07].
Available from: https://www.repository.cam.ac.uk/handle/1810/268520.
Council of Science Editors:
Watson J. Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. [Doctoral Dissertation]. University of Cambridge; 2017. Available from: https://www.repository.cam.ac.uk/handle/1810/268520

University of Cambridge
23.
Watson, Joanna.
Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.
Degree: PhD, 2017, University of Cambridge
URL: https://doi.org/10.17863/CAM.14730
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744281
► Cdc42 is a member of the Rho family of small GTPases, which, together with its homologues RhoA and Rac1, controls a multitude of cellular functions…
(more)
▼ Cdc42 is a member of the Rho family of small GTPases, which, together with its homologues RhoA and Rac1, controls a multitude of cellular functions via the actin cytoskeleton. Cdc42 exerts its effects on the cytoskeleton via effector proteins of the Wiskott-Aldrich Syndrome (WASP) family and the Transducer of Cdc42-dependent Actin assembly (TOCA) family. The WASP family and their activation by Cdc42 have been thoroughly studied in vitro and are well understood. Conversely, understanding of the TOCA family remains limited by a lack of biochemical, biophysical and structural insight. An investigation of the TOCA1-Cdc42 interaction is described here, revealing a relatively low affinity interaction with a dissociation constant in the micromolar range. This is 10-100x weaker than other Rho-effector interactions and suggests that TOCA1 must first be co-localised with Cdc42 to achieve stable binding in vivo. The solution NMR structure of the Cdc42 binding HR1 domain of TOCA1 provides the first structural data on this protein and reveals some interesting structural features that may relate to binding affinity and specificity. A structural model of the Cdc42-HR1 complex provides further insight into differential specificities and affinities of GTPase-effector interactions. NMR and actin polymerisation assays provide insight into the pathway of Cdc42/TOCA1/WASP-dependent actin assembly, suggesting unidirectional displacement of TOCA1 by N-WASP. A comparison of the Cdc42- TOCA1 model with an NMR structure of Cdc42 in complex with the GTPase binding domain of WASP reveals a possible mechanism by which an ‘effector handover’ from TOCA1 to N-WASP could take place. Small GTPases such as Cdc42 are lipid modified and membrane anchored via their C- termini in vivo, so in vitro studies using truncated, unmodified GTPases are limited in their biological interpretation. This project also aimed to develop methods to study full length and membrane-anchored GTPases in vitro. Lipid modified protein was produced, which showed a weak affinity for liposomes, and so structural studies of membrane anchored protein are within reach. Further method development is now required to achieve stable membrane anchoring of lipid modified GTPases for detailed NMR studies.
Subjects/Keywords: 572; Cdc42; NMR; TOCA1; NWASP; WASL; N-WASP; GTPase; G protein; HR1 domain; Filopodia; Endocytosis; Cell signalling; Protein protein interaction
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Watson, J. (2017). Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. (Doctoral Dissertation). University of Cambridge. Retrieved from https://doi.org/10.17863/CAM.14730 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744281
Chicago Manual of Style (16th Edition):
Watson, Joanna. “Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.” 2017. Doctoral Dissertation, University of Cambridge. Accessed March 07, 2021.
https://doi.org/10.17863/CAM.14730 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744281.
MLA Handbook (7th Edition):
Watson, Joanna. “Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP.” 2017. Web. 07 Mar 2021.
Vancouver:
Watson J. Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. [Internet] [Doctoral dissertation]. University of Cambridge; 2017. [cited 2021 Mar 07].
Available from: https://doi.org/10.17863/CAM.14730 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744281.
Council of Science Editors:
Watson J. Structural and biochemical insight into the interactions of Cdc42 with TOCA1 and N-WASP. [Doctoral Dissertation]. University of Cambridge; 2017. Available from: https://doi.org/10.17863/CAM.14730 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744281

Edith Cowan University
24.
Li, Xingang.
Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues.
Degree: 2020, Edith Cowan University
URL: https://ro.ecu.edu.au/theses/2386
► Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with IgG N-glycosylation; however, the causal genes and their abundance in relevant tissues are…
(more)
▼ Genome-wide association studies (GWAS) have identified over 60 genetic loci associated with IgG N-glycosylation; however, the causal genes and their abundance in relevant tissues are uncertain. In this study, firstly, I leveraged data from GWAS summary statistics for 8,090 Europeans, and large-scale expression quantitative trait loci (eQTL) data from the genotype-tissue expression of 53 types of tissues (GTEx v7), to derive a linkage disequilibrium score for the specific expression of genes (LDSC-SEG) and conduct a transcriptome-wide association study (TWAS). I identified 55 genes whose predicted levels of expression were significantly associated with IgG Nglycosylation in 14 tissues with regard to three working scenarios, i.e., tissue-specific, pleiotropic and co-associated, for candidate genetic predisposition affecting IgG N-glycosylation traits. Secondly, through pathway enrichment, I defined 23 of 55 candidate genes being enriched in several IgG N-glycosylation-related pathways, such as asparagine N-linked glycosylation, Nglycan biosynthesis and transport to the Golgi and subsequent modification. Thirdly, through phenome-wide association studies (PheWAS), I found most genetic variants underlying TWAS hits being correlated with health measures (height, waist-hip ratio, systolic blood pressure) and diseases, such as systemic lupus erythematosus, inflammatory bowel disease and Parkinson’s disease, which are related to IgG N-glycosylation. This study provides an atlas of genetic regulatory loci and their target genes within functionally relevant tissues, for further studies on the mechanisms of IgG N-glycosylation and its related diseases.
Subjects/Keywords: Immunoglobulin G; N-glycosylation; transcriptome-wide association study; phenome-wide association study; Cell and Developmental Biology; Genetics and Genomics
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Li, X. (2020). Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues. (Thesis). Edith Cowan University. Retrieved from https://ro.ecu.edu.au/theses/2386
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Li, Xingang. “Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues.” 2020. Thesis, Edith Cowan University. Accessed March 07, 2021.
https://ro.ecu.edu.au/theses/2386.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Li, Xingang. “Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues.” 2020. Web. 07 Mar 2021.
Vancouver:
Li X. Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues. [Internet] [Thesis]. Edith Cowan University; 2020. [cited 2021 Mar 07].
Available from: https://ro.ecu.edu.au/theses/2386.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Li X. Heritability enrichment of immunoglobulin G N-glycosylation relevant genes in specific tissues. [Thesis]. Edith Cowan University; 2020. Available from: https://ro.ecu.edu.au/theses/2386
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
25.
Momège, Benjamin.
Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts.
Degree: Docteur es, Informatique, 2015, Université Blaise-Pascale, Clermont-Ferrand II
URL: http://www.theses.fr/2015CLF22588
► Nous nous intéresserons aux graphes avec conflits (un conflit est une paire d’arêtes ne pouvant pas simultanément faire partie d’un même sous-graphe), dans lesquels nous…
(more)
▼ Nous nous intéresserons aux graphes avec conflits (un conflit est une paire d’arêtes ne pouvant pas simultanément faire partie d’un même sous-graphe), dans lesquels nous étudierons différents types de problèmes liés à l’existence de sous-graphes sans conflit, de nature aussi bien algorithmique que combinatoire, notre ligne directrice étant la notion de connectivité. Nous verrons que plusieurs résultats, simples sans conflit, ne le sont plus lors de l’ajout de conflits. Nous présenterons : des algorithmes exacts (non polynomiaux), des résultats de \mathcal{N P}-complétude, et des conditions suffisantes assurant l’existence de certains objets (arbre couvrant, chemin et cycle hamiltonien) sans conflits.
We will look at graphs with conflicts (conflict is a pair of edges can not simultaneously be part of the same subgraph), in which we will study different types of problems related to the existence of subgraphs without conflict. The nature of the problems is both combinatorial and algorithmic. Our guideline is the notion of connectivity. We will see several results, simple without conflict, are no longer when adding conflicts. We will present exact algorithms (not polynomial), \mathcal{N P}-completeness results and sufficient conditions ensuring the existence of certain objects (spanning tree, path and Hamiltonian cycle) without conflict.
Advisors/Committee Members: Laforest, Christian (thesis director), Kanté, Mamadou Moustapha (thesis director).
Subjects/Keywords: Graphe; Conflit; Transition Interdite; Connexité; Chemin; Parcours; Arbre; Condition Hamiltonienne; Algorithme Exact; \mathcal{N P}-Complétude; Graph; Conflict; Forbidden Transition; Connectivity; Path; Walk; Tree; Hamiltonian Condition; Exact Algorithm; \mathcal{N P}-Completeness
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Momège, B. (2015). Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts. (Doctoral Dissertation). Université Blaise-Pascale, Clermont-Ferrand II. Retrieved from http://www.theses.fr/2015CLF22588
Chicago Manual of Style (16th Edition):
Momège, Benjamin. “Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts.” 2015. Doctoral Dissertation, Université Blaise-Pascale, Clermont-Ferrand II. Accessed March 07, 2021.
http://www.theses.fr/2015CLF22588.
MLA Handbook (7th Edition):
Momège, Benjamin. “Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts.” 2015. Web. 07 Mar 2021.
Vancouver:
Momège B. Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts. [Internet] [Doctoral dissertation]. Université Blaise-Pascale, Clermont-Ferrand II; 2015. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2015CLF22588.
Council of Science Editors:
Momège B. Autour de la connexité dans les graphes avec conflits : On the Connectivity of Graphs with Conflicts. [Doctoral Dissertation]. Université Blaise-Pascale, Clermont-Ferrand II; 2015. Available from: http://www.theses.fr/2015CLF22588
26.
Laouar-Meftah, Siham.
Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.
Degree: 2010, Université M'Hamed Bougara Boumerdès
URL: http://dlibrary.univ-boumerdes.dz:8080123456789/1847
► 138 p. : ill. ; 30 cm
Le but de ce travail est d’étudier numériquement, en régime stationnaire, l’effet du rayonnement de gaz réels sur…
(more)
▼ 138 p. : ill. ; 30 cm
Le but de ce travail est d’étudier numériquement, en régime stationnaire, l’effet du rayonnement de gaz réels sur la convection naturelle de double diffusion laminaire dans une cavité carrée différentiellement chauffée, remplie d’un mélange gazeux binaire (air-CO2 ou air-H2O). La participation radiative du mélange est prise en compte par le modèle spectral de gaz SLW de Denison et Webb. Les effets du rayonnement sont determinés par comparaison avec le cas de la convection naturelle de double diffusion dans un fluide transparent ayant les mêmes caractéristiques que le mélange, mais de coefficient d’absorption nul. Dans le cas aidant, les résultats montrent que le rayonnement modifie un peu la structure de l’écoulement et perturbe le champ thermique et massique, notamment en inclinant leurs lignes iso-valeurs. Le transfert de chaleur total (nombre de Nusselt) est réduit, mais le transfert de masse (nombre de Sherwood) est peu affecté. Dans le cas opposant, les effets radiatifs sont plus importants et dépendent de la nature du régime d’écoulement, en absence de rayonnement. Dans ce cas, le rayonnement réduit le transfert de chaleur total quelque soit le régime de l’écoulement et affecte aussi le transfert de matière, en dehors du régime thermique. L’influence du rayonnement est plus prononcée avec le mélange air-H2O que air-CO2
Subjects/Keywords: Transfert radiatif; Algorithme
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Laouar-Meftah, S. (2010). Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. (Thesis). Université M'Hamed Bougara Boumerdès. Retrieved from http://dlibrary.univ-boumerdes.dz:8080123456789/1847
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Laouar-Meftah, Siham. “Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.” 2010. Thesis, Université M'Hamed Bougara Boumerdès. Accessed March 07, 2021.
http://dlibrary.univ-boumerdes.dz:8080123456789/1847.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Laouar-Meftah, Siham. “Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.” 2010. Web. 07 Mar 2021.
Vancouver:
Laouar-Meftah S. Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. [Internet] [Thesis]. Université M'Hamed Bougara Boumerdès; 2010. [cited 2021 Mar 07].
Available from: http://dlibrary.univ-boumerdes.dz:8080123456789/1847.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Laouar-Meftah S. Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. [Thesis]. Université M'Hamed Bougara Boumerdès; 2010. Available from: http://dlibrary.univ-boumerdes.dz:8080123456789/1847
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
27.
Laouar Meftah, Siham.
Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.
Degree: 2010, Université M'Hamed Bougara Boumerdès
URL: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/776
► 138 p. ; ill. ; 30 cm
Le but de ce travail est d’étudier numériquement, en régime stationnaire, l’effet du rayonnement de gaz réels sur…
(more)
▼ 138 p. ; ill. ; 30 cm
Le but de ce travail est d’étudier numériquement, en régime stationnaire, l’effet du rayonnement de gaz réels sur la convection naturelle de double diffusion laminaire dans une cavité carrée différentiellement chauffée, remplie d’un mélange gazeux binaire (air-CO2 ou air-H2O). La participation radiative du mélange est prise en compte par le modèle spectral de gaz SLW de Denison et Webb. Les effets du rayonnement sont determinés par comparaison avec le cas de la convection naturelle de double diffusion dans un fluide transparent ayant les mêmes caractéristiques que le mélange, mais de coefficient d’absorption nul. Dans le cas aidant, les résultats montrent que le rayonnement modifie un peu la structure de l’écoulement et perturbe le champ thermique et massique, notamment en inclinant leurs lignes iso-valeurs. Le transfert de chaleur total (nombre de Nusselt) est réduit, mais le transfert de masse (nombre de Sherwood) est peu affecté. Dans le cas opposant, les effets radiatifs sont plus importants et dépendent de la nature du régime d’écoulement, en absence de rayonnement. Dans ce cas, le rayonnement réduit le transfert de chaleur total quelque soit le régime de l’écoulement et affecte aussi le transfert de matière, en dehors du régime thermique. L’influence du rayonnement est plus prononcée avec le mélange air-H2O que air-CO2
Subjects/Keywords: Transfert radiatif; Algorithme
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Laouar Meftah, S. (2010). Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. (Thesis). Université M'Hamed Bougara Boumerdès. Retrieved from http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/776
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Laouar Meftah, Siham. “Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.” 2010. Thesis, Université M'Hamed Bougara Boumerdès. Accessed March 07, 2021.
http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/776.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Laouar Meftah, Siham. “Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement.” 2010. Web. 07 Mar 2021.
Vancouver:
Laouar Meftah S. Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. [Internet] [Thesis]. Université M'Hamed Bougara Boumerdès; 2010. [cited 2021 Mar 07].
Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/776.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Laouar Meftah S. Modélisation de la convection naturelle de double diffusion dans un mélange de gaz absorbant et émettant le rayonnement. [Thesis]. Université M'Hamed Bougara Boumerdès; 2010. Available from: http://dlibrary.univ-boumerdes.dz:8080/jspui/handle/123456789/776
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
Langueh, Amavi Mawulé Guissou.
Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue.
Degree: Docteur es, Mécanique, 2013, Université Lille I – Sciences et Technologies
URL: http://www.theses.fr/2013LIL10035
► L'augmentation des charges transportées par essieu, des vitesses de circulation et l’état des voies peuvent conduire à des endommagements des roues en surface ou sous-surface,…
(more)
▼ L'augmentation des charges transportées par essieu, des vitesses de circulation et l’état des voies peuvent conduire à des endommagements des roues en surface ou sous-surface, généralement appelés écaillage. L’objectif de cette thèse est de développer une approche complète de dimensionnement des roues ferroviaires en fatigue de roulement permettant de prendre en compte les sollicitations locales via la géométrie réelle du contact roue/rail, le comportement inélastique du matériau de la roue (acier) et les conditions d'exploitation. A l’heure actuelle, les méthodes de dimensionnement des roues ne permettent pas de prendre en tous ces éléments au travers d’une même simulation. L’algorithme stationnaire fondé sur la formulation eulérienne est utilisé pour déterminer l’état stabilisé de la structure. L’influence du glissement, du mésalignement, de la position du chargement, et de la nuance d’aciers sur la réponse mécanique, les trajets de chargement en fatigue et la limite d’adaptation a été étudiée. Les critères de fatigue de Dang Van et de Manson-Coffin sont principalement utilisés pour l’analyse en fatigue. Les résultats obtenus permettent la construction de cartes d’adaptation numérique et celles-ci sont alors discutées. D'autre part, l’influence des contraintes résiduelles introduites par le traitement thermique de la bande de roulement est analysée. Il est montré qu’elles modifient les contraintes hydrostatiques comme c'est généralement le cas en fatigue, mais aussi le cisaillement mésoscopique, qui constitue un résultat nouveau.
The increasing of the railways axles loads; the traffic speeds and track conditions can lead to surface and sub-surface damage of wheel, usually called scaling. The aim of this thesis is to develop a numerical approach of railways wheel design in rolling contact fatigue which takes into account the local solicitations via the real geometric of rail/wheel contact, the inelastic behavior of the wheel material (steel) and the operating conditions. At present, the simplified methods for the wheel design are not possible to take all these elements through a single simulation. The stationary algorithm based on the Eulerian formulation is used to determine the steady state of the structure. The influence of the slip, the slip angle, the position of the load and the steel grades on the mechanical response, the fatigue loading paths and the shakedown are investigated. For the fatigue analysis, the criteria of Dang Van and Manson-Coffin are used. The results allow the establishment of the numerical shakedown maps and these are then discussed. Furthermore, the influence of residual stresses introduced by the heat treatment of the tread is analysed. It is shown that they modify the hydrostatic pressure as it is usually the case in fatigue, but also the mesoscopic shear stress, which is a new result.
Advisors/Committee Members: Dufrénoy, Philippe (thesis director), Charkaluk, Éric (thesis director), Brunel, Jean-François (thesis director).
Subjects/Keywords: Algorithme stationnaire; 625.21
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Langueh, A. M. G. (2013). Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2013LIL10035
Chicago Manual of Style (16th Edition):
Langueh, Amavi Mawulé Guissou. “Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue.” 2013. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed March 07, 2021.
http://www.theses.fr/2013LIL10035.
MLA Handbook (7th Edition):
Langueh, Amavi Mawulé Guissou. “Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue.” 2013. Web. 07 Mar 2021.
Vancouver:
Langueh AMG. Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2013. [cited 2021 Mar 07].
Available from: http://www.theses.fr/2013LIL10035.
Council of Science Editors:
Langueh AMG. Contribution au dimensionnement des roues ferroviaires en fatigue de contact de roulement : Contribution to the design of railway wheels in rolling contact fatigue. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2013. Available from: http://www.theses.fr/2013LIL10035

University of Oulu
29.
Markkanen, P. (Piia).
Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking.
Degree: 2012, University of Oulu
URL: http://urn.fi/urn:isbn:9789514298219
► Abstract The delta opioid receptor (δOR) is a member of the G protein-coupled receptor family. This transmembrane receptor has an important role in the regulation…
(more)
▼ Abstract
The delta opioid receptor (δOR) is a member of the G protein-coupled receptor family. This transmembrane receptor has an important role in the regulation of pain. The OPRD1 gene that encodes the human δOR (hδOR) contains at least 11 single-nucleotide polymorphisms (SNPs). The only nonsynonymous SNP resides in the amino-terminal (N-terminal) domain of the receptor and it replaces Phe at position 27 with Cys, thus introducing an unpaired Cys residue on the extracellular surface of the receptor. The Cys27 variant has been shown to have an allelic frequency of about 10% in Caucasian populations. The polymorphic site is flanked by two putative N-glycosylation sites at Asn18 and Asn33. In this study, the folding, maturation and trafficking of hδOR was assessed using the hδORPhe27 and hδORCys27 variants and the N-glycosylation deficient forms of the latter as models in a heterologous expression system. The effects of N-glycosylation and the unpaired Cys-residue were studied with various biochemical, pharmacological and cell biological methods. In addition, protein-protein interactions of the intracellular hδOR precursors were assessed.
The hδORCys27 and hδORPhe27 variants differed significantly in their subcellular localization and maturation efficiency. The newly synthesized hδORCys27 was found to accumulate in the endoplasmic reticulum (ER) prior to its ER-associated degradation in proteasomes. Although a slow maturation rate was characteristic for both variants, only the hδORCys27 had poor maturation efficiency. The cell surface expression of hδORCys27 was further decreased because the constitutive internalization of this receptor was enhanced compared to hδORPhe27.
N-linked glycosylation was not required for hδOR function or ligand binding, but was important for the expression of the correctly folded receptor species at the cell surface. The mutant non-N-glycosylated receptor was shown to traffic to the cell surface with enhanced kinetics, but some of the plasma membrane receptors were in a nonnative conformation. Also, the overall levels of the non-N-glycosylated hδORCys27 were decreased as the receptor was efficiently internalized for lysosomal degradation in a constitutive fashion.
The hδORCys27 and hδORPhe27 precursors were found to interact with several ER localized proteins, such as calnexin (CNX), protein disulfide isomerase (PDI) and ERp72. The receptors also associated with the sarco(endo)plasmic reticulum calcium ATPase 2b (SERCA2b), which was shown to occur during translocation of the receptor to the ER membrane or immediately thereafter. The interaction was not receptor N-glycan dependent and the normal functional activity of SERCA2b was shown to be required for proper cell surface expression of hδOR.
Tiivistelmä
δ-opioidireseptori kuuluu G-proteiinikytkentäisiin reseptoreihin, ja sillä on tärkeä rooli kivun säätelyssä. Ihmisen δ-opioidireseptoria koodaavassa OPRD1 geenissä on havaittu ainakin…
Advisors/Committee Members: Petäjä-Repo, U. (Ulla).
Subjects/Keywords: ER quality control; ER-associated degradation; G protein-coupled receptor; N-linked glycosylation; SERCA; biosynthesis; endoplasmic reticulum; internalization; molecular chaperone; opioid receptor; polymorphism; G-proteiinikytkentäinen reseptori; N-glykosylaatio; SERCA; endoplasmakalvosto; endoplasmakalvoston laadunvalvonta; endoplasmakalvostoon kytkeytynyt proteiinihajotus; internalisaatio; molekulaarinen kaperoni; opioidireseptori; polymorfia
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Markkanen, P. (. (2012). Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking. (Doctoral Dissertation). University of Oulu. Retrieved from http://urn.fi/urn:isbn:9789514298219
Chicago Manual of Style (16th Edition):
Markkanen, P (Piia). “Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking.” 2012. Doctoral Dissertation, University of Oulu. Accessed March 07, 2021.
http://urn.fi/urn:isbn:9789514298219.
MLA Handbook (7th Edition):
Markkanen, P (Piia). “Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking.” 2012. Web. 07 Mar 2021.
Vancouver:
Markkanen P(. Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking. [Internet] [Doctoral dissertation]. University of Oulu; 2012. [cited 2021 Mar 07].
Available from: http://urn.fi/urn:isbn:9789514298219.
Council of Science Editors:
Markkanen P(. Human δ opioid receptor:the effect of Phe27Cys polymorphism, N-linked glycosylation and SERCA2b interaction on receptor processing and trafficking. [Doctoral Dissertation]. University of Oulu; 2012. Available from: http://urn.fi/urn:isbn:9789514298219

Brno University of Technology
30.
Götthans, Jakub.
Problematika bezdrátových sítí: Wireless Network.
Degree: 2018, Brno University of Technology
URL: http://hdl.handle.net/11012/9578
► The aim of this work is to design and realization of WLAN at GK SERVIS, spol. s r.o. The conception will be verified by measuring…
(more)
▼ The aim of this work is to design and realization of WLAN at GK SERVIS, spol. s r.o. The conception will be verified by measuring the functionality, security and reliability. The thesis is divided into theoretical, analytical and practical. The first part will discuss the theoretical problems of processing of wireless networks, in the second part analyzed the current status of LAN and WLAN in the last section has been prepared by the project and subsequently realized.
Advisors/Committee Members: Koch, Miloš (advisor), Hruboš, Zdeněk (referee).
Subjects/Keywords: Bezdrátové sítě; bezdrátové připojení; Alohanet; CSMA; TDMA; FDMA; CDMA; GSM; Wi-Fi; WiMAX; IEEE 802.11a/b/g/n/ad; Mikrotik; Wireless networks; wireless connection; Alohanet; CSMA; TDMA; FDMA; CDMA; GSM; Wi-Fi; WiMAX; IEEE 802.11a/b/g/n/ad; Mikrotik
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Götthans, J. (2018). Problematika bezdrátových sítí: Wireless Network. (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/9578
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Götthans, Jakub. “Problematika bezdrátových sítí: Wireless Network.” 2018. Thesis, Brno University of Technology. Accessed March 07, 2021.
http://hdl.handle.net/11012/9578.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Götthans, Jakub. “Problematika bezdrátových sítí: Wireless Network.” 2018. Web. 07 Mar 2021.
Vancouver:
Götthans J. Problematika bezdrátových sítí: Wireless Network. [Internet] [Thesis]. Brno University of Technology; 2018. [cited 2021 Mar 07].
Available from: http://hdl.handle.net/11012/9578.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Götthans J. Problematika bezdrátových sítí: Wireless Network. [Thesis]. Brno University of Technology; 2018. Available from: http://hdl.handle.net/11012/9578
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
◁ [1] [2] [3] [4] [5] … [412] ▶
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