subject:(Alcohol Physiological effect)

California State University – East Bay

1. Coshnear, Hank. Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit.

Degree: 2016, California State University – East Bay

URL: http://hdl.handle.net/10211.3/164279

► This research demonstrates that the neurons in the nucleus accumbens, locus coeruleus, and anterior insula that coordinate to mediate alcohol abuse behavior such as aversion-resistant… (more)

Subjects/Keywords: Alcohol – Physiological effect

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APA (6^th Edition):

Coshnear, H. (2016). Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit. (Thesis). California State University – East Bay. Retrieved from http://hdl.handle.net/10211.3/164279

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Coshnear, Hank. “Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit.” 2016. Thesis, California State University – East Bay. Accessed January 18, 2021. http://hdl.handle.net/10211.3/164279.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Coshnear, Hank. “Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit.” 2016. Web. 18 Jan 2021.

Vancouver:

Coshnear H. Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit. [Internet] [Thesis]. California State University – East Bay; 2016. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10211.3/164279.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Coshnear H. Tracing of Accumbens and Amygdala Neurons Reveals Distinct Clusters in the Compulsive Alcohol-seeking Circuit. [Thesis]. California State University – East Bay; 2016. Available from: http://hdl.handle.net/10211.3/164279

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Oregon State University

2. Yeh, Lee-chuan C. Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat.

Degree: PhD, Foods and Nutrition, 1984, Oregon State University

URL: http://hdl.handle.net/1957/27147

► This research was designed to study the perinatal and postweaning effects of the interaction between ethanol and low dietary zinc during gestation and lactation in… (more)

▼ This research was designed to study the perinatal and postweaning effects of the interaction between ethanol and low dietary zinc during gestation and lactation in the rat. Pregnant rats were fed liquid diets containing either 2 or 10 μg zinc/ml with or without 30% of kcal from ethanol throughout gestation and lactation. The liquid diet formulation was nutritionally adequate to insure offspring growth and survival during lactation. At weaning, dams and five of eight offspring from each litter were killed by exsanguination under sodium pentobarbital anesthesia. The remaining offspring were orally inoculated with Streptococcus mutans and fed a caries-promoting diet for six weeks. The low zinc diet produced a moderate zinc deficiency in dams as evidenced by a decrease in tissue zinc content, serum alkaline phosphatase activity, and urinary zinc concentration. Despite the presence of high zinc content in the diet, ethanol antagonized maternal zinc status to a level typical of that produced by the low zinc diet. The lowest zinc status, however, was found when low dietary zinc and ethanol were combined. The maternal interaction between ethanol and zinc also depressed offspring serum zinc and alkaline phosphatase activity in a similar manner but the magnitude was smaller. The maintenance of a lower than normal maternal tissue zinc and decreased maternal urinary excretion of zinc suggested a maternal attempt to support the growth and development of offspring despite zinc deficiency. Physiological consequences of ethanol-antagonized zinc status were evidenced by depressed activity of maternal and offspring serum alkaline phosphatase, increased maternal urinary excretion of hydroxyproline, decreased offspring molar enamel and dentin zinc content, increased dental caries score, and decreased cross-linking structure of mandibular second molar enamel. The liquid diet developed in the present study was nutritionally adequate and allowed for the investigation of a single nutrient deficiency, zinc, in ethanol fed rats during gestation and lactation without confounding effects of general malnutrition. Although the direction of interaction was predominately an effect of ethanol on zinc rather than the effect of zinc on ethanol, this study clearly indicates that zinc deficiency is an important consequence of maternal ethanol ingestion. Advisors/Committee Members: Cerklewski, Florian L. (advisor), Woodburn, Margy J. (committee member).

Subjects/Keywords: Alcohol – Physiological effect

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APA (6^th Edition):

Yeh, L. C. (1984). Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat. (Doctoral Dissertation). Oregon State University. Retrieved from http://hdl.handle.net/1957/27147

Chicago Manual of Style (16^th Edition):

Yeh, Lee-chuan C. “Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat.” 1984. Doctoral Dissertation, Oregon State University. Accessed January 18, 2021. http://hdl.handle.net/1957/27147.

MLA Handbook (7^th Edition):

Yeh, Lee-chuan C. “Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat.” 1984. Web. 18 Jan 2021.

Vancouver:

Yeh LC. Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat. [Internet] [Doctoral dissertation]. Oregon State University; 1984. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/1957/27147.

Council of Science Editors:

Yeh LC. Perinatal and postweaning effects of the interaction between maternal ethanol ingestion and low dietary zinc in the rat. [Doctoral Dissertation]. Oregon State University; 1984. Available from: http://hdl.handle.net/1957/27147

Oregon State University

3. Astell, Rebecca L. Influence of ethanol on copper utilization by pregnant and growing rats.

Degree: MS, Foods and Nutrition, 1988, Oregon State University

URL: http://hdl.handle.net/1957/27126

► Pregnant and weanling rats were fed liquid diets with or without 30 percent of total kcal from ethanol and varying levels of copper in order… (more)

Subjects/Keywords: Alcohol – Physiological effect

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APA (6^th Edition):

Astell, R. L. (1988). Influence of ethanol on copper utilization by pregnant and growing rats. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/27126

Chicago Manual of Style (16^th Edition):

Astell, Rebecca L. “Influence of ethanol on copper utilization by pregnant and growing rats.” 1988. Masters Thesis, Oregon State University. Accessed January 18, 2021. http://hdl.handle.net/1957/27126.

MLA Handbook (7^th Edition):

Astell, Rebecca L. “Influence of ethanol on copper utilization by pregnant and growing rats.” 1988. Web. 18 Jan 2021.

Vancouver:

Astell RL. Influence of ethanol on copper utilization by pregnant and growing rats. [Internet] [Masters thesis]. Oregon State University; 1988. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/1957/27126.

Council of Science Editors:

Astell RL. Influence of ethanol on copper utilization by pregnant and growing rats. [Masters Thesis]. Oregon State University; 1988. Available from: http://hdl.handle.net/1957/27126

University of Johannesburg

4. Kruger, Estelle. A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo.

Degree: 2012, University of Johannesburg

URL: http://hdl.handle.net/10210/7192

►

M.Tech.

Alcohol intoxication is often linked to crime, motor vehicle accidents, violence and acts of aggression. There is currently no reversal agent or antidote available… (more)

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M.Tech.

Alcohol intoxication is often linked to crime, motor vehicle accidents, violence and acts of aggression. There is currently no reversal agent or antidote available for alcohol intoxication. A study conducted by the University of Johannesburg, reports positive results when using Chelidonium 3cH and 30cH to reduce breath alcohol levels. Homeopathy is a therapeutic system based primarily on the Law of Similars. The drug picture of Chelidonium majus is well matched to the symptom picture of acute alcohol intoxication and is thus a well-indicated remedy to treat the symptoms of this condition. The aim of this study was to determine the efficacy of the homeopathic preparations Chelidonium majus 3cH and 30cH to reduce breath alcohol levels when compared to a placebo. This was a double blind, placebo controlled study. The sample groups were recruited using advertisements at the University of Johannesburg Doornfontein Campus and surrounding areas and consisted of thirty male participants between 20 and 45 years of age. Participants were required to attend three experimental sessions. The researcher completed a selection form to exclude interested parties with abnormal vital sign readings, diabetes, drug or alcohol addiction, history of cerebrovascular accident (stroke), diagnosed hypotension or hypertension, diagnosed hyperlipidaemia, liver or gallbladder disease, recent head trauma, taking any medication contra-indicating alcohol ingestion or history of chronic cardiac or renal disease. The Widmark formula was used to determine the exact amount of 43% brandy, diluted with cola drink to obtain a 20% volume-to-volume dilution. These calculations were done according to the weight of each participant to ensure that their breath alcohol concentrations were increased to the legal limit of 0.08 mg/dL. In the first session, the participants only consumed the alcohol to establish a baseline reading for their breath alcohol levels. During session two participants in the experimental group received a single powder medicated with Chelidonium majus 3cH. Participants in the placebo group received an unmedicated powder. During session three participants in the experimental group received a single powder medicated with Chelidonium majus 30cH. Participants in the placebo group received an unmedicated powder. During each session breath alcohol measurements were taken and recorded at twenty minutes, forty minutes, sixty minutes and eighty minutes after the initial alcoholic beverage has been ingested. The breath alcohol readings were statistically analysed and compared by Ms. Riette Eiselen, Head: Statistical Consultation Services (STATKOM), University of Johannesburg. Independent sample t-tests and a Mann-Whitney test were used to determine if there was any significant difference between the median breath alcohol reductions of the experimental and the control group. These tests indicated that there was no significant difference between the median breath alcohol reductions of the experimental and the control group on any variable at…

Subjects/Keywords: Alcohol - Physiological effect; Alcoholism - Homeopathic treatment

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APA (6^th Edition):

Kruger, E. (2012). A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo. (Thesis). University of Johannesburg. Retrieved from http://hdl.handle.net/10210/7192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kruger, Estelle. “A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo.” 2012. Thesis, University of Johannesburg. Accessed January 18, 2021. http://hdl.handle.net/10210/7192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kruger, Estelle. “A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo.” 2012. Web. 18 Jan 2021.

Vancouver:

Kruger E. A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo. [Internet] [Thesis]. University of Johannesburg; 2012. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10210/7192.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kruger E. A study to determine the efficacy of Chelidonium majus 3cH and 30cH in reducing breath alcohol levels when compared to a placebo. [Thesis]. University of Johannesburg; 2012. Available from: http://hdl.handle.net/10210/7192

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Montana Tech

5. Dill, Richard. AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT.

Degree: PhD, 1980, Montana Tech

URL: https://scholarworks.umt.edu/etd/10067

Subjects/Keywords: Alcohol Physiological effect.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dill, R. (1980). AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT. (Doctoral Dissertation). Montana Tech. Retrieved from https://scholarworks.umt.edu/etd/10067

Chicago Manual of Style (16^th Edition):

Dill, Richard. “AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT.” 1980. Doctoral Dissertation, Montana Tech. Accessed January 18, 2021. https://scholarworks.umt.edu/etd/10067.

MLA Handbook (7^th Edition):

Dill, Richard. “AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT.” 1980. Web. 18 Jan 2021.

Vancouver:

Dill R. AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT. [Internet] [Doctoral dissertation]. Montana Tech; 1980. [cited 2021 Jan 18]. Available from: https://scholarworks.umt.edu/etd/10067.

Council of Science Editors:

Dill R. AN ASSOCIATIVE ANALYSIS OF THE ALCOHOL TOLERANCE EFFECT. [Doctoral Dissertation]. Montana Tech; 1980. Available from: https://scholarworks.umt.edu/etd/10067

Rutgers University

6. Datar, Ketaki Rajendra, 1994-. The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis.

Degree: MS, Microbiology and Molecular Genetics, 2019, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/61726/

► Breast cancer is the most common cancer in women worldwide and in 2019 it is estimated that approximately 41,000 women will die from the disease.… (more)

▼ Breast cancer is the most common cancer in women worldwide and in 2019 it is estimated that approximately 41,000 women will die from the disease. There are a variety of factors that increase risk for breast cancer one of which is alcohol consumption. However, the mechanism that underlies this increased risk is unknown. The mammary gland is a dynamic organ composed of a multiple cell types including adipose cells, fibroblasts, immune cells, and epithelial cells. The epithelial cells can be categorized into luminal and basal epithelial cells, whose composition is maintained and controlled by a pool of mammary stem cells. Mammary stem cells are quiescent and long lived, and therefore have the potential to accumulate mutations and transform into breast cancer stem cells. Breast cancer stem cells have the potential to maintain a tumor and may not be irradiated by conventional therapies, leading to relapse. Therefore, understanding what regulates the overall mammary epithelial cell hierarchy is key to improving breast cancer treatments. The goal of this project was to determine whether alcohol consumption alters the mammary epithelial cell composition to favor a tumorigenic state, whether alcohol consumption affects tumor latency, and whether alcohol alters the mammary tumor epithelial cell composition. The MMTV-Wnt1 mouse model is a useful model for studying the role of mammary stem cells in breast cancer, as the tumors that develop in this model arise from a stem or stem-like cell, and downstream targets of the Wnt signaling cascade have been found to be upregulated in breast cancer. To investigate the effect of alcohol on mammary epithelial cell composition and tumorigenesis, 7- week old MMTV-Wnt1 female mice were given a 20% alcohol solution in place of drinking water sweetened with 0.2% saccharin. Control animals were given a 0.12% saccharin solution for the entire duration of the study. Animals were weighed once per week and were sacrificed after either 8 weeks to analyze the preneoplastic mammary gland or after the first tumor had reached 1.5cm in diameter. Animals in the alcohol group gained more weight compared to the controls, and this difference in weight gain was due to an increase in overall caloric intake due to alcohol consumption. Mammary epithelial cells were isolated and analyzed by flow cytometry and plated for mammosphere/tumorsphere assays. Mammary glands from the alcohol group exhibited an increase in the luminal progenitor population, but a decrease in mammosphere forming efficiency. Alcohol consumption decreased tumor latency in animals that presented with tumors by 43 weeks of age, however, alcohol consumption did not effect on the tumor epithelial cell composition nor the tumorsphere forming efficiency. Alcohol consumption decreased the expression of the epithelial-mesenchymal transition (EMT) factors Snail and Twist in the mammary gland mRNA, and the proliferation marker Ki67. It also decreased expression of Snail in mRNA from the mammary tumor. Alcohol did not affect estrogen… Advisors/Committee Members: Cohick, Wendie S (chair), Belden, William J (internal member), Suh, Nanjoo (internal member), School of Graduate Studies.

Subjects/Keywords: Mammary; Breast – Cancer; Alcohol – Physiological effect

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APA (6^th Edition):

Datar, Ketaki Rajendra, 1. (2019). The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/61726/

Chicago Manual of Style (16^th Edition):

Datar, Ketaki Rajendra, 1994-. “The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis.” 2019. Masters Thesis, Rutgers University. Accessed January 18, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/61726/.

MLA Handbook (7^th Edition):

Datar, Ketaki Rajendra, 1994-. “The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis.” 2019. Web. 18 Jan 2021.

Vancouver:

Datar, Ketaki Rajendra 1. The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis. [Internet] [Masters thesis]. Rutgers University; 2019. [cited 2021 Jan 18]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61726/.

Council of Science Editors:

Datar, Ketaki Rajendra 1. The effect of alcohol consumption on mammary epithelial cell composition and mammary tumorigenesis. [Masters Thesis]. Rutgers University; 2019. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/61726/

Simon Fraser University

7. Datar, Rekha. The effects of alcohol consumption on planning for movement.

Degree: 1988, Simon Fraser University

URL: http://summit.sfu.ca/item/5382

Subjects/Keywords: Alcohol – Physiological effect.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Datar, R. (1988). The effects of alcohol consumption on planning for movement. (Thesis). Simon Fraser University. Retrieved from http://summit.sfu.ca/item/5382

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Datar, Rekha. “The effects of alcohol consumption on planning for movement.” 1988. Thesis, Simon Fraser University. Accessed January 18, 2021. http://summit.sfu.ca/item/5382.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Datar, Rekha. “The effects of alcohol consumption on planning for movement.” 1988. Web. 18 Jan 2021.

Vancouver:

Datar R. The effects of alcohol consumption on planning for movement. [Internet] [Thesis]. Simon Fraser University; 1988. [cited 2021 Jan 18]. Available from: http://summit.sfu.ca/item/5382.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Datar R. The effects of alcohol consumption on planning for movement. [Thesis]. Simon Fraser University; 1988. Available from: http://summit.sfu.ca/item/5382

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Texas

8. Levitt, Danielle E. The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines.

Degree: 2015, University of North Texas

URL: https://digital.library.unt.edu/ark:/67531/metadc804851/

► The purpose of this study was to examine the effect of post-resistance exercise alcohol ingestion on LPS-stimulated production of IFNγ, TNF-α, IL-1β, IL-6, IL-8, and… (more)

▼ The purpose of this study was to examine the effect of post-resistance exercise alcohol ingestion on LPS-stimulated production of IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10. Recreationally resistance-trained men (n = 10, 25 ± 3 yr, 177 ± 7 cm, 83.8 ± 15.7 kg, 14.8 ± 8.5% body fat) and women (n = 8, 23 ± 2 yr, 161 ± 3 cm, 59.5 ± 6.0 kg, 26.5 ± 3.0% body fat) completed the study. Participants visited the laboratory for an initial visit at which time they were screened, familiarized with procedures, and had their 1-repetition maximum (1RM) back squat tested. Subsequently, participants visited the laboratory 2 more times and completed 2 identical heavy resistance exercise bouts (6 sets of 10 repetitions of 80% 1RM back squat) after which a beverage, either containing alcohol (alcohol condition, ALC; 1.09 g EtOH per kg fat free mass) or water (placebo condition, PLA), was administered. Blood samples were collected before exercise (PRE), and at 3 hours (3h) and 5 hours (5h) after exercise. Samples were stimulated with lipopolysaccharide (LPS) and cultured overnight. Supernatant was collected and analyzed for IFNγ, TNF-α, IL-1β, IL-6, IL-8, and IL-10. A significant (p < 0.05) main effect for time was found for IFNγ, TNF-α, and IL-1β (5h greater than PRE) and for IL-10 (5h less than PRE and 3h, 3h less than PRE). An interaction effect was found for IL-8 (ALC less than PLA at 5h) and for IL-6 (ALC greater than PLA at PRE and ALC less than PLA at 3h). For IL-6, ALC was less at 3h than at PRE, and PLA was greater at 3h than at PRE. Overall, the LPS-stimulated cytokine response was pro-inflammatory by 5h. Alcohol consumed after heavy resistance exercise reduced LPS-stimulated production of IL-6 and IL-8 but not of IFNγ, TNF-α, IL-1β, or IL-10. These data indicate that alcohol affected inflammatory capacity but that the potential effect of alcohol on the production of cytokines in response to LPS was largely overwhelmed by the resistance exercise bout. Advisors/Committee Members: Vingren, Jakob L., McFarlin, Brian K., Hill, David Wilfred, 1952-.

Subjects/Keywords: Alcohol; resistance exercise; inflammation; cytokines; Alcohol – Physiological effect.; Cytokines.; Isometric exercise.

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APA (6^th Edition):

Levitt, D. E. (2015). The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines. (Thesis). University of North Texas. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc804851/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Levitt, Danielle E. “The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines.” 2015. Thesis, University of North Texas. Accessed January 18, 2021. https://digital.library.unt.edu/ark:/67531/metadc804851/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Levitt, Danielle E. “The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines.” 2015. Web. 18 Jan 2021.

Vancouver:

Levitt DE. The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines. [Internet] [Thesis]. University of North Texas; 2015. [cited 2021 Jan 18]. Available from: https://digital.library.unt.edu/ark:/67531/metadc804851/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Levitt DE. The Effect of Post-resistance Exercise Alcohol Ingestion on LPS-stimulated Cytokines. [Thesis]. University of North Texas; 2015. Available from: https://digital.library.unt.edu/ark:/67531/metadc804851/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Rutgers University

9. Polanco, Tiffany, 1982-. Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis.

Degree: PhD, Animal Sciences, 2011, Rutgers University

URL: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061439

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Altered fetal programming as a result of a suboptimal in utero environment can increase disease susceptibility in adulthood. Alcohol exposure in utero increases mammary cancer… (more)

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Altered fetal programming as a result of a suboptimal in utero environment can increase disease susceptibility in adulthood. Alcohol exposure in utero increases mammary cancer risk in rodents. Mammary development affects breast cancer risk, as a denser, hyperproliferative gland increases mammary cancer risk. Therefore we hypothesized that alcohol exposure in utero increases the action of the IGF-I/E2 system leading to hyperproliferative mammary glands and ultimately increased cancer susceptibility. We first established a model where fetal alcohol leads to increased mammary tumor susceptibility. Pregnant rats were fed a liquid diet containing ethanol (alcohol-fed), a control isocaloric liquid diet, or rat chow ad libitum. Alcohol-fed dams were acclimated to increasing concentrations of ethanol (2.2% and 4.4%), then fed 6.7% ethanol from day 7 to 21 of gestation. To investigate tumorigenesis, N-nitroso-N-methlyurea (NMU) was administered to induce tumor formation at postnatal day 50. Rats were palpated for iii tumors weekly and euthanized at 23 weeks post-NMU injection, or in a second study at 16 weeks post-injection. At 16 weeks post-injection, tumor multiplicity was greater and tumor latency was decreased in the alcohol-fed group compared to controls. At 23 weeks post-NMU injection alcohol-fed animals developed more malignant tumors and more estrogen receptor-α negative tumors with less IGF binding protein-5 expression relative to controls, indicative of poor prognosis breast cancer in women. To determine if mammary development is altered by in utero alcohol exposure, a study was conducted in which animals were euthanized prepubertally and postpubertally. Mammary glands from alcohol-fed animals showed increased proliferation and aromatase expression prior to and immediately after puberty. Mammary and hepatic IGF-I mRNA levels were also higher in alcohol-fed animals. In a separate study it was determined that alcohol-fed animals also have higher circulation E2 than controls. Together, these data indicate that alcohol exposure in utero increases susceptibility to mammary tumorigenesis, and leads to a tumor phenotype indicative of poor prognosis breast cancer. These changes may be related to enhanced early mammary development via the IGF/E2 systems. Therefore, women born to mothers who drank alcohol during pregnancy may represent a high risk group for aggressive breast cancer.

Advisors/Committee Members: Polanco, Tiffany, 1982- (author), Cohick, Wendie S (chair), Sarkar, Dipak (internal member), Katz, Larry (internal member), Thomas, Paul (outside member).

Subjects/Keywords: Children of prenatal alcohol abuse; Breast – Cancer – Etiology; Alcohol – Physiological effect

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APA (6^th Edition):

Polanco, Tiffany, 1. (2011). Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis. (Doctoral Dissertation). Rutgers University. Retrieved from http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061439

Chicago Manual of Style (16^th Edition):

Polanco, Tiffany, 1982-. “Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis.” 2011. Doctoral Dissertation, Rutgers University. Accessed January 18, 2021. http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061439.

MLA Handbook (7^th Edition):

Polanco, Tiffany, 1982-. “Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis.” 2011. Web. 18 Jan 2021.

Vancouver:

Polanco, Tiffany 1. Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis. [Internet] [Doctoral dissertation]. Rutgers University; 2011. [cited 2021 Jan 18]. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061439.

Council of Science Editors:

Polanco, Tiffany 1. Effect of fetal alcohol on mammary carcinogenesis: the role of the estrogen/IGF axis. [Doctoral Dissertation]. Rutgers University; 2011. Available from: http://hdl.rutgers.edu/1782.1/rucore10001600001.ETD.000061439

Rhodes University

10. Mayson, Tamara Ann. The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students.

Degree: MA, Faculty of Humanities, Psychology, 2016, Rhodes University

URL: http://hdl.handle.net/10962/d1020327

► Introduction: Studies reveal differential cognitive effects of alcohol use, with moderate to heavy alcohol having some beneficial effects in older adults, whereas in young adulthood,… (more)

▼ Introduction: Studies reveal differential cognitive effects of alcohol use, with moderate to heavy alcohol having some beneficial effects in older adults, whereas in young adulthood, heavier alcohol use produces deficits. The aim of the research was to investigate the relationship between patterns of alcohol use and the cognitive and symptomatic functioning of university students over one year, and to discern which demographic, clinical and alcohol factors might moderate cognitive outcomes. Method: The sample included undergraduate Psychology students from a South African University, aged 18 to 23 years (n = 86). The sample was divided into two alcohol use groups based on four categories from the Alcohol Use Disorders Identification Test (AUDIT) (Babor et al., 2001), including a lighter drinking group (Safe/Hazardous, n = 74) and a heavier drinking group (Harmful/Dependent, n = 12). The two drinking groups were statistically equivalent for distribution of age, gender, English first language, race groups, history of neurological or psychiatric vulnerability, a measure of initial intelligence/cognitive reserve (Peabody Picture Vocabulary Test: PPVT-4) (Dunn & Dunn, 2007) and for a measure of test-taking validity (Immediate Postconcussion Assessment and Cognitive Test: ImPACT Impulse Control) (p = < 0.05 in all instances). Participants were tested on the computerized ImPACT battery (ImPACT, 2007) at three intervals over an academic year (May, August, October 2012). Repeated measures ANOVAs were used to investigate cognitive and symptomatic differences between the two alcohol use groups, in association with moderating factors. Results: The heavier drinking group revealed: (i) poorer performance on ImPACT Visual Motor Speed, Reaction Time and Cognitive Efficiency Index scores, including less ability to benefit from practice over time; (ii) symptom reports of severe Numbness/Tingling, Balance problems and Dizziness. Deleterious cognitive outcome was exacerbated by longer lifetime duration of alcohol use, passing out monthly, beer or wine drinking, smoking or substance use. Conclusion: Deleterious cognitive and symptomatic effects of heavy alcohol use are in evidence for undergraduate university students implicating current and/or cumulative alcohol induced brain impairment. The results of the study are of concern for optimal academic performance of students at an early stage of university level study, who engage in heavier (Harmful/Dependent) drinking patterns, with negative implications for future career attainment. Advisors/Committee Members: Young, Charles, Edwards, Ann.

Subjects/Keywords: Drinking of alcholic beverages – South Africa; Rhodes University – Students – Alcohol use; Alcohol – Physiological effect

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APA (6^th Edition):

Mayson, T. A. (2016). The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students. (Masters Thesis). Rhodes University. Retrieved from http://hdl.handle.net/10962/d1020327

Chicago Manual of Style (16^th Edition):

Mayson, Tamara Ann. “The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students.” 2016. Masters Thesis, Rhodes University. Accessed January 18, 2021. http://hdl.handle.net/10962/d1020327.

MLA Handbook (7^th Edition):

Mayson, Tamara Ann. “The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students.” 2016. Web. 18 Jan 2021.

Vancouver:

Mayson TA. The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students. [Internet] [Masters thesis]. Rhodes University; 2016. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10962/d1020327.

Council of Science Editors:

Mayson TA. The relationship between the alcohol use patterns and cognitive and symptomatic functioning of Rhodes University students. [Masters Thesis]. Rhodes University; 2016. Available from: http://hdl.handle.net/10962/d1020327

University of North Texas

11. Duplanty, Anthony A. Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle.

Degree: 2015, University of North Texas

URL: https://digital.library.unt.edu/ark:/67531/metadc804831/

► The purpose of this project was to further elucidate the effects post-exercise alcohol ingestion. This project had many novel aspects including using a resistance exercise… (more)

Subjects/Keywords: mTORC1; alcohol; resistance exercise; Isometric exercise.; Alcohol – Physiological effect.; Testosterone.; Bone – Density.; Muscles.

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APA (6^th Edition):

Duplanty, A. A. (2015). Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle. (Thesis). University of North Texas. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc804831/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Duplanty, Anthony A. “Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle.” 2015. Thesis, University of North Texas. Accessed January 18, 2021. https://digital.library.unt.edu/ark:/67531/metadc804831/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Duplanty, Anthony A. “Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle.” 2015. Web. 18 Jan 2021.

Vancouver:

Duplanty AA. Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle. [Internet] [Thesis]. University of North Texas; 2015. [cited 2021 Jan 18]. Available from: https://digital.library.unt.edu/ark:/67531/metadc804831/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Duplanty AA. Effect of Acute Alcohol Ingestion on Resistance Exercise Induced mTORC1 Signaling in Human Muscle. [Thesis]. University of North Texas; 2015. Available from: https://digital.library.unt.edu/ark:/67531/metadc804831/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Gaddini, Gino W. Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model.

Degree: MS, Nutrition, 2013, Oregon State University

URL: http://hdl.handle.net/1957/42308

► Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this… (more)

Subjects/Keywords: Alcohol – Physiological effect

…examined in rodents. To understand the effect of alcohol on intracortical bone remodeling, and… …documented negative physiological consequences of alcohol abuse date back to the 11th century A.D… …concentrations would likely be a better measure to assess the skeletal effect of alcohol compared to… …effects on numerous physiological systems. Alcohol may affect the intake, absorption, metabolism… …Resorption �� . 25 3.7 Blood Alcohol Concentrations ��…. �� ...….. 25 3.8 Statistical…

12 more images…

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APA (6^th Edition):

Gaddini, G. W. (2013). Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model. (Masters Thesis). Oregon State University. Retrieved from http://hdl.handle.net/1957/42308

Chicago Manual of Style (16^th Edition):

Gaddini, Gino W. “Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model.” 2013. Masters Thesis, Oregon State University. Accessed January 18, 2021. http://hdl.handle.net/1957/42308.

MLA Handbook (7^th Edition):

Gaddini, Gino W. “Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model.” 2013. Web. 18 Jan 2021.

Vancouver:

Gaddini GW. Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model. [Internet] [Masters thesis]. Oregon State University; 2013. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/1957/42308.

Council of Science Editors:

Gaddini GW. Effects of 12 months of voluntary alcohol self-administration on intracortical bone remodeling in a rhesus macaque model. [Masters Thesis]. Oregon State University; 2013. Available from: http://hdl.handle.net/1957/42308

Michigan State University

13. Hartocollis, Peter. Effects of alcohol on verbal performance.

Degree: PhD, 1954, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:44483

Subjects/Keywords: Alcohol – Physiological effect; Speech

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APA (6^th Edition):

Hartocollis, P. (1954). Effects of alcohol on verbal performance. (Doctoral Dissertation). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:44483

Chicago Manual of Style (16^th Edition):

Hartocollis, Peter. “Effects of alcohol on verbal performance.” 1954. Doctoral Dissertation, Michigan State University. Accessed January 18, 2021. http://etd.lib.msu.edu/islandora/object/etd:44483.

MLA Handbook (7^th Edition):

Hartocollis, Peter. “Effects of alcohol on verbal performance.” 1954. Web. 18 Jan 2021.

Vancouver:

Hartocollis P. Effects of alcohol on verbal performance. [Internet] [Doctoral dissertation]. Michigan State University; 1954. [cited 2021 Jan 18]. Available from: http://etd.lib.msu.edu/islandora/object/etd:44483.

Council of Science Editors:

Hartocollis P. Effects of alcohol on verbal performance. [Doctoral Dissertation]. Michigan State University; 1954. Available from: http://etd.lib.msu.edu/islandora/object/etd:44483

University of Arizona

14. Lung, Chien-Cheng, 1960-. Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates .

Degree: 1987, University of Arizona

URL: http://hdl.handle.net/10150/276603

► Acetaldehyde, the first metabolite of ethanol, has been implicated in the pathogenesis of alcoholic liver disease. In order to investigate a possible immunologic mechanism whereby… (more)

Subjects/Keywords: Alcohol – Physiological effect.; Immunotoxicology.

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APA (6^th Edition):

Lung, Chien-Cheng, 1. (1987). Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates . (Masters Thesis). University of Arizona. Retrieved from http://hdl.handle.net/10150/276603

Chicago Manual of Style (16^th Edition):

Lung, Chien-Cheng, 1960-. “Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates .” 1987. Masters Thesis, University of Arizona. Accessed January 18, 2021. http://hdl.handle.net/10150/276603.

MLA Handbook (7^th Edition):

Lung, Chien-Cheng, 1960-. “Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates .” 1987. Web. 18 Jan 2021.

Vancouver:

Lung, Chien-Cheng 1. Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates . [Internet] [Masters thesis]. University of Arizona; 1987. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10150/276603.

Council of Science Editors:

Lung, Chien-Cheng 1. Production and in vitro characterization of antibody against acetaldehyde rabbit serum albumin conjugates . [Masters Thesis]. University of Arizona; 1987. Available from: http://hdl.handle.net/10150/276603

Texas Tech University

15. Spence, Mary Tedford. Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory.

Degree: Psychology, 1970, Texas Tech University

URL: http://hdl.handle.net/2346/20469

Subjects/Keywords: Alcohol – Physiological effect; Memory

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APA (6^th Edition):

Spence, M. T. (1970). Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory. (Thesis). Texas Tech University. Retrieved from http://hdl.handle.net/2346/20469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Spence, Mary Tedford. “Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory.” 1970. Thesis, Texas Tech University. Accessed January 18, 2021. http://hdl.handle.net/2346/20469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Spence, Mary Tedford. “Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory.” 1970. Web. 18 Jan 2021.

Vancouver:

Spence MT. Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory. [Internet] [Thesis]. Texas Tech University; 1970. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2346/20469.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Spence MT. Effects of Alcohol, Information Reduction and Speed Load on Short-Term Memory. [Thesis]. Texas Tech University; 1970. Available from: http://hdl.handle.net/2346/20469

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McGill University

16. Zeichner, Amos. Alcohol and aggression : the role of behavior contingencies and instigator intent.

Degree: PhD, Department of Psychology, 1978, McGill University

URL: https://escholarship.mcgill.ca/downloads/3n2041642.pdf ; https://escholarship.mcgill.ca/concern/theses/tt44pq48d

►

The purpose of the present investigation was to determine the mediating effect of alcohol, behavior contingencies and instigator-intent on aggression in male social drinkers. Aggression… (more)

Subjects/Keywords: Aggressiveness.; Alcohol – Physiological effect.

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APA (6^th Edition):

Zeichner, A. (1978). Alcohol and aggression : the role of behavior contingencies and instigator intent. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/3n2041642.pdf ; https://escholarship.mcgill.ca/concern/theses/tt44pq48d

Chicago Manual of Style (16^th Edition):

Zeichner, Amos. “Alcohol and aggression : the role of behavior contingencies and instigator intent.” 1978. Doctoral Dissertation, McGill University. Accessed January 18, 2021. https://escholarship.mcgill.ca/downloads/3n2041642.pdf ; https://escholarship.mcgill.ca/concern/theses/tt44pq48d.

MLA Handbook (7^th Edition):

Zeichner, Amos. “Alcohol and aggression : the role of behavior contingencies and instigator intent.” 1978. Web. 18 Jan 2021.

Vancouver:

Zeichner A. Alcohol and aggression : the role of behavior contingencies and instigator intent. [Internet] [Doctoral dissertation]. McGill University; 1978. [cited 2021 Jan 18]. Available from: https://escholarship.mcgill.ca/downloads/3n2041642.pdf ; https://escholarship.mcgill.ca/concern/theses/tt44pq48d.

Council of Science Editors:

Zeichner A. Alcohol and aggression : the role of behavior contingencies and instigator intent. [Doctoral Dissertation]. McGill University; 1978. Available from: https://escholarship.mcgill.ca/downloads/3n2041642.pdf ; https://escholarship.mcgill.ca/concern/theses/tt44pq48d

Rutgers University

17. Nolan, Bonnie. An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:.

Degree: PhD, Neuroscience, 2009, Rutgers University

URL: http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051061

►

Excessive alcohol consumption is known to result in fatty liver, or steatosis. A high-fat, low-carbohydrate diet also results in fatty liver. Furthermore, fatty liver is… (more)

▼

Excessive alcohol consumption is known to result in fatty liver, or steatosis. A high-fat, low-carbohydrate diet also results in fatty liver. Furthermore, fatty liver is known to precede cirrhosis in both animals and humans, and cirrhosis precedes primary hepatocellular carcinoma in humans. A series of studies was first undertaken to determine whether exercise and/or certain dietary manipulations could affect fatty liver. Long-Evans rats were given either a high-fat, low-carbohydrate or a high-carbohydrate, low-fat version of liquid diet with or without alcohol. Livers were analyzed for fat and measures of carbohydrate metabolism in liver and plasma were taken, as well as blood glucose alcohol concentrations. Next, added exercise (run wheel), caffeine, antioxidants such as Vitamin E, diphenyl-para-phenylene diamine (DPPD), and selenium were examined as were the dietary additives cranberry powder and soy protein. Finally, based on ambiguous results involving each agent separately, caffeine and DPPD were combined. Following the conclusion of rat studies, C57BL6 mice were given a modified version of the Leiber-deCarli liquid diet with alcohol. The calorie manipulation described above was repeated in mice to determine whether alcohol-induced fatty liver would be exacerbated in the presence of a high-fat diet. Subsequently, the dietary additives Vitamin E, DPPD and Trolox were added. Striatum was taken for HPLC, and livers were taken for liver fat analysis and malondialdehyde (MDA) assay (as a measure of oxidative stress) respectively. Finally, an experiment was undertaken to determine a time course for withdrawal seizures in mice. In rats, differences in liver glycogen did not account for differences in liver fat. Exercise and caffeine both resulted in significant changes in weight gain, and while combined they appeared to reduce alcohol-induced fatty liver, the effect was not significant. Separately, no protective properties of either exercise or caffeine were observed. Vitamin E and selenium were found to exacerbate alcohol-induced fatty liver, while DPPD did not. Neither cranberry powder nor soy protein affected alcohol-induced fatty liver. DPPD combined with caffeine reduced alcohol-induced fatty liver significantly (p<0.05). Adult mice were able to tolerate 4.5% ethanol in a high-fat liquid diet. The high-fat diet resulted in liver fat values significantly higher than high-carbohydrate when combined with alcohol. Vitamin E appeared to exacerbate fatty liver in mice, but differences were not significant. There were significant differences in oxidative stress; Vitamin E and Trolox reduced MDA significantly over diet plus alcohol alone. All animals experienced withdrawal seizures between 3 and 5 hours after removal of alcohol. There were significant differences in serotonin turnover (5HIAA/5HT) in animals fed a high-fat diet without alcohol vs. chow controls.

Advisors/Committee Members: Nolan, Bonnie (author), Wagner, George (chair), Kusnecov, Alexander (internal member), Martin, Joseph (internal member), Fisher, Hans (outside member).

Subjects/Keywords: Alcohol – Physiological effect; Liver – Diseases

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APA (6^th Edition):

Nolan, B. (2009). An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:. (Doctoral Dissertation). Rutgers University. Retrieved from http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051061

Chicago Manual of Style (16^th Edition):

Nolan, Bonnie. “An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:.” 2009. Doctoral Dissertation, Rutgers University. Accessed January 18, 2021. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051061.

MLA Handbook (7^th Edition):

Nolan, Bonnie. “An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:.” 2009. Web. 18 Jan 2021.

Vancouver:

Nolan B. An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:. [Internet] [Doctoral dissertation]. Rutgers University; 2009. [cited 2021 Jan 18]. Available from: http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051061.

Council of Science Editors:

Nolan B. An analysis of the effects of various compounds on alcohol and high-fat-diet-induced steatosis in rats and mice:. [Doctoral Dissertation]. Rutgers University; 2009. Available from: http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051061

Simon Fraser University

18. Parker, Kenneth Gordon. A psychophysiological assessment of the association between alcohol and sexual arousal.

Degree: 1984, Simon Fraser University

URL: http://summit.sfu.ca/item/5939

Subjects/Keywords: Alcohol – Physiological effect.; Sexual excitement.

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APA (6^th Edition):

Parker, K. G. (1984). A psychophysiological assessment of the association between alcohol and sexual arousal. (Thesis). Simon Fraser University. Retrieved from http://summit.sfu.ca/item/5939

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Parker, Kenneth Gordon. “A psychophysiological assessment of the association between alcohol and sexual arousal.” 1984. Thesis, Simon Fraser University. Accessed January 18, 2021. http://summit.sfu.ca/item/5939.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Parker, Kenneth Gordon. “A psychophysiological assessment of the association between alcohol and sexual arousal.” 1984. Web. 18 Jan 2021.

Vancouver:

Parker KG. A psychophysiological assessment of the association between alcohol and sexual arousal. [Internet] [Thesis]. Simon Fraser University; 1984. [cited 2021 Jan 18]. Available from: http://summit.sfu.ca/item/5939.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Parker KG. A psychophysiological assessment of the association between alcohol and sexual arousal. [Thesis]. Simon Fraser University; 1984. Available from: http://summit.sfu.ca/item/5939

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Texas

19. Budnar, Jr., Ronald G. The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women.

Degree: 2015, University of North Texas

URL: https://digital.library.unt.edu/ark:/67531/metadc822770/

► The purpose of this study was to examine the hormonal response to acute ethanol ingestion following a bout of heavy resistance exercise in women. Eight… (more)

Subjects/Keywords: alcohol; hormones; resistance exercise; women; Alcohol in the body – Physiological effect.; Isometric exercise.; Exercise for women – Physiological aspects.; Hormones.

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APA (6^th Edition):

Budnar, Jr., R. G. (2015). The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women. (Thesis). University of North Texas. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc822770/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Budnar, Jr., Ronald G. “The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women.” 2015. Thesis, University of North Texas. Accessed January 18, 2021. https://digital.library.unt.edu/ark:/67531/metadc822770/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Budnar, Jr., Ronald G. “The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women.” 2015. Web. 18 Jan 2021.

Vancouver:

Budnar, Jr. RG. The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women. [Internet] [Thesis]. University of North Texas; 2015. [cited 2021 Jan 18]. Available from: https://digital.library.unt.edu/ark:/67531/metadc822770/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Budnar, Jr. RG. The Effect of Post-exercise Ethanol Consumption on the Acute Hormonal Response to Heavy Resistance Exercise in Women. [Thesis]. University of North Texas; 2015. Available from: https://digital.library.unt.edu/ark:/67531/metadc822770/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

20. Gurney, Robert James. The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures.

Degree: MS, Department of Physical Education and Sport Studies, 1983, University of Alberta

URL: https://era.library.ualberta.ca/files/d791sj18p

Subjects/Keywords: Cold – Physiological effect.; Body temperature – Regulation.; Alcohol – Physiological effect.

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APA (6^th Edition):

Gurney, R. J. (1983). The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/d791sj18p

Chicago Manual of Style (16^th Edition):

Gurney, Robert James. “The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures.” 1983. Masters Thesis, University of Alberta. Accessed January 18, 2021. https://era.library.ualberta.ca/files/d791sj18p.

MLA Handbook (7^th Edition):

Gurney, Robert James. “The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures.” 1983. Web. 18 Jan 2021.

Vancouver:

Gurney RJ. The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures. [Internet] [Masters thesis]. University of Alberta; 1983. [cited 2021 Jan 18]. Available from: https://era.library.ualberta.ca/files/d791sj18p.

Council of Science Editors:

Gurney RJ. The effects of ethanol on thermoregulatory mechanisms in men exercising in two different environmental temperatures. [Masters Thesis]. University of Alberta; 1983. Available from: https://era.library.ualberta.ca/files/d791sj18p

Baylor University

21. Helfand, Rebecca S. Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety.

Degree: MA, Psychology and Neuroscience., 2007, Baylor University

URL: http://hdl.handle.net/2104/5059

► Adolescents exhibit few negative neurobehavioral effects of ethanol withdrawal and have higher levels of taurine, an inhibitory amino acid, than adults. Given taurine’s neuroprotective role… (more)

Subjects/Keywords: Taurine.; Taurine – Physiological effect.; Alcohol – Physiological effect.

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APA (6^th Edition):

Helfand, R. S. (2007). Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety. (Masters Thesis). Baylor University. Retrieved from http://hdl.handle.net/2104/5059

Chicago Manual of Style (16^th Edition):

Helfand, Rebecca S. “Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety.” 2007. Masters Thesis, Baylor University. Accessed January 18, 2021. http://hdl.handle.net/2104/5059.

MLA Handbook (7^th Edition):

Helfand, Rebecca S. “Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety.” 2007. Web. 18 Jan 2021.

Vancouver:

Helfand RS. Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety. [Internet] [Masters thesis]. Baylor University; 2007. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2104/5059.

Council of Science Editors:

Helfand RS. Taurine depletion in adolescent mice and implications for ethanol withdrawal-induced anxiety. [Masters Thesis]. Baylor University; 2007. Available from: http://hdl.handle.net/2104/5059

University of North Carolina – Wilmington

22. Cramond, Alexander J. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.

Degree: 2009, University of North Carolina – Wilmington

URL: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=1550

► A large body of research suggests that individuals are accurate at subjectively judging their own alcohol intoxication when assessed relative to blood alcohol concentration. Although… (more)

Subjects/Keywords: Caffeine – Physiological effect; Alcohol – Physiological effect; Human behavior

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APA (6^th Edition):

Cramond, A. J. (2009). Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. (Masters Thesis). University of North Carolina – Wilmington. Retrieved from http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=1550

Chicago Manual of Style (16^th Edition):

Cramond, Alexander J. “Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.” 2009. Masters Thesis, University of North Carolina – Wilmington. Accessed January 18, 2021. http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=1550.

MLA Handbook (7^th Edition):

Cramond, Alexander J. “Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.” 2009. Web. 18 Jan 2021.

Vancouver:

Cramond AJ. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. [Internet] [Masters thesis]. University of North Carolina – Wilmington; 2009. [cited 2021 Jan 18]. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=1550.

Council of Science Editors:

Cramond AJ. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. [Masters Thesis]. University of North Carolina – Wilmington; 2009. Available from: http://libres.uncg.edu/ir/listing.aspx?styp=ti&id=1550

23. Cramond, Alexander J. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.

Degree: 2009, NC Docks

URL: http://libres.uncg.edu/ir/uncw/f/cramonda2005-3.pdf

► A large body of research suggests that individuals are accurate at subjectively judging their own alcohol intoxication when assessed relative to blood alcohol concentration. Although… (more)

Subjects/Keywords: Caffeine – Physiological effect; Alcohol – Physiological effect; Human behavior

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APA (6^th Edition):

Cramond, A. J. (2009). Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. (Thesis). NC Docks. Retrieved from http://libres.uncg.edu/ir/uncw/f/cramonda2005-3.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cramond, Alexander J. “Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.” 2009. Thesis, NC Docks. Accessed January 18, 2021. http://libres.uncg.edu/ir/uncw/f/cramonda2005-3.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cramond, Alexander J. “Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication.” 2009. Web. 18 Jan 2021.

Vancouver:

Cramond AJ. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. [Internet] [Thesis]. NC Docks; 2009. [cited 2021 Jan 18]. Available from: http://libres.uncg.edu/ir/uncw/f/cramonda2005-3.pdf.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cramond AJ. Sobering up : the interactive effects of alcohol and caffeine on perceived intoxication. [Thesis]. NC Docks; 2009. Available from: http://libres.uncg.edu/ir/uncw/f/cramonda2005-3.pdf

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hong Kong

24. Poon, Yuk-king, Karen. The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats.

Degree: 1989, University of Hong Kong

URL: http://hdl.handle.net/10722/32625

Subjects/Keywords: Acetaminophen - Physiological effect.; Acetaminophen; Alcohol - Physiological effect.; Rats - Physiology.

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APA (6^th Edition):

Poon, Yuk-king, K. (1989). The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats. (Thesis). University of Hong Kong. Retrieved from http://hdl.handle.net/10722/32625

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Poon, Yuk-king, Karen. “The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats.” 1989. Thesis, University of Hong Kong. Accessed January 18, 2021. http://hdl.handle.net/10722/32625.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Poon, Yuk-king, Karen. “The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats.” 1989. Web. 18 Jan 2021.

Vancouver:

Poon, Yuk-king K. The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats. [Internet] [Thesis]. University of Hong Kong; 1989. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/10722/32625.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Poon, Yuk-king K. The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats. [Thesis]. University of Hong Kong; 1989. Available from: http://hdl.handle.net/10722/32625

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McGill University

25. Bélanger-Grou, Hélène. Preference For and Tolerance to Ethanol : Acetaldehyde Involvement.

Degree: PhD, Department of Psychology, 1984, McGill University

URL: https://escholarship.mcgill.ca/downloads/st74cs93c.pdf ; https://escholarship.mcgill.ca/concern/theses/cn69m653x

►

This thesis is concerned with problems of current interest in the computer-aided simulation of synchronous machines. It deals with the application of the finite element… (more)

Subjects/Keywords: Rats – Behavior.; Aldehydes – Physiological effect.; Alcohol – Physiological effect.

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APA (6^th Edition):

Bélanger-Grou, H. (1984). Preference For and Tolerance to Ethanol : Acetaldehyde Involvement. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/st74cs93c.pdf ; https://escholarship.mcgill.ca/concern/theses/cn69m653x

Chicago Manual of Style (16^th Edition):

Bélanger-Grou, Hélène. “Preference For and Tolerance to Ethanol : Acetaldehyde Involvement.” 1984. Doctoral Dissertation, McGill University. Accessed January 18, 2021. https://escholarship.mcgill.ca/downloads/st74cs93c.pdf ; https://escholarship.mcgill.ca/concern/theses/cn69m653x.

MLA Handbook (7^th Edition):

Bélanger-Grou, Hélène. “Preference For and Tolerance to Ethanol : Acetaldehyde Involvement.” 1984. Web. 18 Jan 2021.

Vancouver:

Bélanger-Grou H. Preference For and Tolerance to Ethanol : Acetaldehyde Involvement. [Internet] [Doctoral dissertation]. McGill University; 1984. [cited 2021 Jan 18]. Available from: https://escholarship.mcgill.ca/downloads/st74cs93c.pdf ; https://escholarship.mcgill.ca/concern/theses/cn69m653x.

Council of Science Editors:

Bélanger-Grou H. Preference For and Tolerance to Ethanol : Acetaldehyde Involvement. [Doctoral Dissertation]. McGill University; 1984. Available from: https://escholarship.mcgill.ca/downloads/st74cs93c.pdf ; https://escholarship.mcgill.ca/concern/theses/cn69m653x

26. Spinetta, Michael John. Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?.

Degree: PhD, Psychology, 2008, University of Texas – Austin

URL: http://hdl.handle.net/2152/17788

► The work in this dissertation aims to describe a simple new test for odor-recognition memory in rats that can be readily performed and results in… (more)

Subjects/Keywords: Amnesia; Alcohol – Physiological effect; Caffeine – Physiological effect

…effect has been further vii investigated mechanistically and attributed to caffeine’s dual… …relation to learning. A review of acute alcohol intoxication by Fleming (1935) revealed… …that the consumption of alcohol can impair the acquisition of new information in learning… …tests of memory conducted the next day or have no effect (De Carvalho, Vendite… …been no systematic examination of the possible retrograde influence of high doses of alcohol…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Spinetta, M. J. (2008). Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/17788

Chicago Manual of Style (16^th Edition):

Spinetta, Michael John. “Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?.” 2008. Doctoral Dissertation, University of Texas – Austin. Accessed January 18, 2021. http://hdl.handle.net/2152/17788.

MLA Handbook (7^th Edition):

Spinetta, Michael John. “Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?.” 2008. Web. 18 Jan 2021.

Vancouver:

Spinetta MJ. Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2008. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2152/17788.

Council of Science Editors:

Spinetta MJ. Ethanol and retrograde amnesia : can rats have blackouts and does caffeine help?. [Doctoral Dissertation]. University of Texas – Austin; 2008. Available from: http://hdl.handle.net/2152/17788

University of Texas – Austin

27. Doyon, William Maurice. The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration.

Degree: PhD, Pharmacy, 2005, University of Texas – Austin

URL: http://hdl.handle.net/2152/2416

► A key process associated with the development of reinforcement is the release of dopamine in the nucleus accumbens from mesolimbic cells of the ventral tegmental… (more)

▼ A key process associated with the development of reinforcement is the release of dopamine in the nucleus accumbens from mesolimbic cells of the ventral tegmental area. There is evidence that accumbal dopamine activity increases during operant ethanol self-administration, but it is unknown whether this effect is related to appetitive or consummatory aspects of behavior. Neuroadaptations in the mesolimbic system during the development of ethanol reinforcement are also unclear. Studies were undertaken to address these issues, all of which measured dopamine and ethanol concentrations in the nucleus accumbens of rats using a procedure in which a fixed number of operant responses was followed by 20 min of ethanol availability. An initial exposure to 5 or 10% ethanol (with sucrose) resulted in reduced intake levels compared to controls and no alterations in dopamine concentrations during consumption. In contrast, during limited self-administration (about 7 days) of 10% ethanol (with sucrose) or long term self-administration (over 40 days) of 10% ethanol, a brief rise in dopamine levels occurred within 5 min of access that corresponded to consumption. During the period in which the dopamine response occurred, brain ethanol concentrations were low but increased progressively thereafter, indicating a rapid dissociation between the two time courses. Together these results suggest that the dopamine response was due to factors other than the pharmacological properties of ethanol, such as the stimulus cues of the solution during acquisition. These data also suggest that a dopamine response to ethanol occurs after the development of motivated ethanol drinking. Furthermore, accumbal dopamine activity during ethanol self-administration may be under the regulation of the endogenous κ-opioid system, acting to suppress dopamine activity and ethanol intake. We tested this hypothesis by blocking the κ-opioid receptor with nor binaltorphimine during ethanol self-administration. Nor-binaltorphimine treatment resulted in a brief increase in dopamine concentration 20 min after ethanol drinking commenced. The latent rise in dopamine levels correlated positively with accumbal ethanol concentration, suggesting that kappa blockade uncovered a pharmacological stimulation of dopamine activity by ethanol. Advisors/Committee Members: Gonzales, Rueben A. (advisor).

Subjects/Keywords: Alcohol – Physiological effect; Dopamine – Physiological effect; Opioids – Receptors

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APA (6^th Edition):

Doyon, W. M. (2005). The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/2416

Chicago Manual of Style (16^th Edition):

Doyon, William Maurice. “The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration.” 2005. Doctoral Dissertation, University of Texas – Austin. Accessed January 18, 2021. http://hdl.handle.net/2152/2416.

MLA Handbook (7^th Edition):

Doyon, William Maurice. “The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration.” 2005. Web. 18 Jan 2021.

Vancouver:

Doyon WM. The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2005. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2152/2416.

Council of Science Editors:

Doyon WM. The effect of ethanol consumption on dopamine and ethanol concentrations in the nucleus accumbens during the development of reinforcement and the involvement of the k-Opioid receptor in the modulation of dopamine activity during ethanol self-administration. [Doctoral Dissertation]. University of Texas – Austin; 2005. Available from: http://hdl.handle.net/2152/2416

University of Texas – Austin

28. Diaz, Laurea Marie. Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants.

Degree: PhD, Pharmacy, 2005, University of Texas – Austin

URL: http://hdl.handle.net/2152/1536

► The mesolimbic pathway has been implicated in the rewarding effects of drugs of abuse, and an important component of this pathway is the D1 dopamine… (more)

▼ The mesolimbic pathway has been implicated in the rewarding effects of drugs of abuse, and an important component of this pathway is the D1 dopamine receptor (D1DR). D1DRs desensitize upon agonist stimulation by several mechanisms, including a process involving receptor clustering and internalization. This process removes postsynaptic D1DRs and may be a neuroadaptive mechanism associated with addiction to drugs of abuse, including ethanol. We measured localization of D1DRs in viable nucleus accumbens (NAcc) neurons from parasagittal explants. A sindbis RNA virus was used to mediate the expression of D1DRs containing an enhanced green fluorescent protein (eGFP) tag in these explants. The effects of dopamine and ethanol on D1DR localization were measured by changes in fluorescence intensity using two-photon laser scanning microscopy. Two-dimensional images from z-stacks of virally infected neurons displayed stable and homogenous fluorescence throughout the neuronal soma and processes. Dopamine (100 uM, 30 min) significantly enhanced the greatest increase of maximum fluorescence intensity in distinct regions of interest (ROIs) by approximately 40% compared to control neurons in the absence of dopamine. Ethanol pretreatment significantly enhanced dopamine-induced clustering. Neurons exposed to dopamine (50 uM, 30 min) displayed receptor clustering only when pretreated with ethanol. Ethanol (50 and 100 mM, 30 min.) pretreatment followed by dopamine (50 uM, 30 min.) enhanced the greatest increase of maximum fluorescence intensity by 44±3 and 108±9%, respectively, while dopamine (50 uM, 30 min) in the absence of ethanol pretreatment showed no clustering with peak increases in maximum fluorescence intensity of only 3±2%. Ethanol (50 and 100 mM, 60 min) alone enhance the greatest increase of maximum fluorescence intensity by about 60% for both concentrations. Receptor clustering induced by dopamine, ethanol pretreatment of dopamine, or ethanol alone was partially blocked by the D1DR antagonist SCH 23390 (20 uM). These findings show that both dopamine and ethanol alter D1DR localization in NAcc neurons and suggest that a physical restructuring of D1DRs in this region may be involved in neuroadaptive mechanisms of ethanol action Advisors/Committee Members: Morrisett, Richard A. (advisor).

Subjects/Keywords: Dopamine – Receptors; Dopamine – Physiological effect; Alcohol – Physiological effect

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Diaz, L. M. (2005). Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/1536

Chicago Manual of Style (16^th Edition):

Diaz, Laurea Marie. “Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants.” 2005. Doctoral Dissertation, University of Texas – Austin. Accessed January 18, 2021. http://hdl.handle.net/2152/1536.

MLA Handbook (7^th Edition):

Diaz, Laurea Marie. “Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants.” 2005. Web. 18 Jan 2021.

Vancouver:

Diaz LM. Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2005. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2152/1536.

Council of Science Editors:

Diaz LM. Dopamine and ethanol induced trafficking of viral mediated eGFP tagged dopamine D1 receptors in parasagittal explants. [Doctoral Dissertation]. University of Texas – Austin; 2005. Available from: http://hdl.handle.net/2152/1536

University of Texas – Austin

29. Zhang, Tao. Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens.

Degree: PhD, Neuroscience, 2005, University of Texas – Austin

URL: http://hdl.handle.net/2152/2213

Subjects/Keywords: Methyl aspartate – Receptors; Dopamine – Physiological effect; Alcohol – Physiological effect

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zhang, T. (2005). Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/2213

Chicago Manual of Style (16^th Edition):

Zhang, Tao. “Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens.” 2005. Doctoral Dissertation, University of Texas – Austin. Accessed January 18, 2021. http://hdl.handle.net/2152/2213.

MLA Handbook (7^th Edition):

Zhang, Tao. “Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens.” 2005. Web. 18 Jan 2021.

Vancouver:

Zhang T. Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2005. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2152/2213.

Council of Science Editors:

Zhang T. Dopamine D1-like receptor-mediated regulation of NMDA receptor sensitivity to ethanol in the nucleus accumbens. [Doctoral Dissertation]. University of Texas – Austin; 2005. Available from: http://hdl.handle.net/2152/2213

University of Texas – Austin

30. Roberts, Michael Thomas. Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function.

Degree: PhD, Cell and Molecular Biology, 2005, University of Texas – Austin

URL: http://hdl.handle.net/2152/2290

► Alcohol and volatile anesthetics enhance the function of the glycine receptor (GlyR), an inhibitory neurotransmitter-gated ion channel. Increasing evidence suggests that this enhancement results from… (more)

▼ Alcohol and volatile anesthetics enhance the function of the glycine receptor (GlyR), an inhibitory neurotransmitter-gated ion channel. Increasing evidence suggests that this enhancement results from direct interactions of these drugs with a binding pocket located between the transmembrane domains of each of the five subunits that compose a GlyR. We hypothesized that only one of the five binding pockets per receptor pentamer need be occupied by drug in order to achieve enhancement of receptor function. To test this hypothesis, a serine to cysteine point mutation at binding pocket residue 267 (S267C) was utilized for its ability to be covalently labeled by the thiol reagent propyl methanethiosulfonate (PMTS). By coinjecting Xenopus oocytes with increasing ratios of wt:S267C cDNAs, heteromeric GlyRs containing a single S267C subunit were expressed. Using two-electrode voltage clamp electrophysiology, we observed that PMTS labeling viii of these receptors resulted in irreversible enhancement of receptor currents, indicating that drug occupancy of one binding pocket per receptor pentamer is sufficient to enhance GlyR function. We next investigated the possibility that binding pocket residues might directly influence the channel gate by examining the effects of point mutations at two such residues on channel kinetics. Single-channel recordings of an alanine 288 to tryptophan (A288W) mutation in HEK 293 cells revealed a large increase in the stability of the channel open state, while single-channel recordings of an S267 to glutamine (S267Q) mutation demonstrated a large destabilization of the channel open state. Despite significant evidence that volatile anesthetics enhance GlyR function, the single-channel kinetics underlying this modulation remain unknown. We examined halothane and isoflurane modulation of wild type GlyR single-channel activity in outside-out patches pulled from transiently transfected HEK 293 cells. Analysis revealed that these volatile anesthetics enhance receptor function by stabilizing the channel open state, increasing the mean duration of bursts of openings, and increasing the mean number of openings per burst. These data indicate that volatile anesthetics enhance GlyR function through kinetic mechanisms similar to those by which allosteric modulators enhance GABAA receptor function. Advisors/Committee Members: Mihic, S. John (advisor).

Subjects/Keywords: Neurotransmitter receptors; Anesthetics – Physiological effect; Alcohol – Physiological effect; Glycine

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APA (6^th Edition):

Roberts, M. T. (2005). Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function. (Doctoral Dissertation). University of Texas – Austin. Retrieved from http://hdl.handle.net/2152/2290

Chicago Manual of Style (16^th Edition):

Roberts, Michael Thomas. “Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function.” 2005. Doctoral Dissertation, University of Texas – Austin. Accessed January 18, 2021. http://hdl.handle.net/2152/2290.

MLA Handbook (7^th Edition):

Roberts, Michael Thomas. “Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function.” 2005. Web. 18 Jan 2021.

Vancouver:

Roberts MT. Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function. [Internet] [Doctoral dissertation]. University of Texas – Austin; 2005. [cited 2021 Jan 18]. Available from: http://hdl.handle.net/2152/2290.

Council of Science Editors:

Roberts MT. Molecular mechanisms of alcohol and volatile anesthetic modulation of glycine receptor function. [Doctoral Dissertation]. University of Texas – Austin; 2005. Available from: http://hdl.handle.net/2152/2290

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