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Universitat Rovira i Virgili

1. Salas Figueroa, Patricia Maria del Rosario. Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability.

Degree: Departament de Pedagogia, 2008, Universitat Rovira i Virgili

Research aim: to study the development of compensating strategies to the auditory deficit in subjective processes of educational integration in deaf persons. Method: a case study of five deaf persons who finished higher education was carried out. The starting point was another case study done by said researcher but based on non-participatory observation. The corresponding results took the researcher to the restatement of the research aim into a different perspective: the individuals' integration point of view. The analysis was performed from three focus of attention: studies on language and its relation to the auditory disability, considerations on the topic of educational integration in said individuals and contributions taken from areas of knowledge closely connected to the biographic-narrative investigation in education. The research was performed in two consecutive stages. During the first one, five autobiographic writings were analyzed based on a contrastive case study. Following a qualitative focus, two levels of analysis were determined: the author's and the narrator's. The first one refers to the real being who wrote the writings. The second one is a construction arising from the discourse itself and represents the perceptions the researched individuals had on their own integration processes. The second stage corresponds exactly to the biographic-narrative methodology and studies deeply one of the previous stage cases. Besides the autobiography, others instruments were used, such as interviews with the autobiographic text author through MSN, other interviews were carried out in situ with primary and secondary teachers at the referenced institutions and others were done with the deaf persons' relatives. Data were processed at a first level of analysis by means of a biogram that was then interpreted at a second level of analysis by means of a narrative report. Results: the research showed that deaf persons, independently of their auditory loss degree and of their prosthesis development, could overcome -when compensating strategies to the deficit were developed- the obstacles coming from the educational system and became strengthened from their own experiences, thus turning them into the basis for future development. These experiences are built on the base of their own efforts and perseverance, as well as on the institutions' understanding and knowledge of the problem. Integration was shown from the individuals' own perspective who -however having a developed linguistic competence- found out reading as a way of compensating the cultural deficiency caused by deafness. Conclusions: the results obtained help the construction of a new identity in this group of persons. Such identity defined neither from the deficit nor from its rejection, but from the desire to be part of the hearing majority culture; however, this does not mean they have to abandon the minority culture they belong to. Inclusion in Spanish speaking people's culture -as in this case- is only possible if… Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), González Soto, Ángel Pío (director).

Subjects/Keywords: lenjuaje-sordos-integración; 316; 376; 572; 8

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Salas Figueroa, P. M. d. R. (2008). Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability. (Thesis). Universitat Rovira i Virgili. Retrieved from http://hdl.handle.net/10803/8936

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Salas Figueroa, Patricia Maria del Rosario. “Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability.” 2008. Thesis, Universitat Rovira i Virgili. Accessed October 23, 2017. http://hdl.handle.net/10803/8936.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Salas Figueroa, Patricia Maria del Rosario. “Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability.” 2008. Web. 23 Oct 2017.

Vancouver:

Salas Figueroa PMdR. Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability. [Internet] [Thesis]. Universitat Rovira i Virgili; 2008. [cited 2017 Oct 23]. Available from: http://hdl.handle.net/10803/8936.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Salas Figueroa PMdR. Narrativa, Lenguaje y Educación. Aproximación a un estudio de casos de Integración Educativa desde la discapacidad auditiva: Approximation to a case study in educational integration from the point of view of the auditory disability. [Thesis]. Universitat Rovira i Virgili; 2008. Available from: http://hdl.handle.net/10803/8936

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Rahier-Corticchiato, Renaud. Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities.

Degree: Docteur es, Biochimie, 2016, Lyon

La phospholipase D (PLD) hydrolyse les phospholipides membranaires en libérant leur tête polaire afin de générer l'acide phosphatidique (PA), impliqué dans la signalisation cellulaire. Pour comprendre les propriétés biochimiques des PLDs, les travaux présentés ont été réalisés autour de deux axes. Le premier axe concerne l'expression recombinante et la purification de la PLDa d'Arabidopsis thaliana (AtPLDa) dans la levure Pichia pastoris. La détermination de la séquence N-terminale a révélé que l'AtPLDa est amputée de ses 35 premiers résidus, suggérant ainsi la participation d'un mécanisme de maturation. Cependant, la région N-terminale des PLDs de plantes est homologue au domaine C2, impliqué dans leur interaction Ca2+-dépendante avec la membrane. Afin d'évaluer l'impact d'un tel clivage, les domaines C2 de l'AtPLDa mais également de l'AtPLDß, à titre de comparaison, ont été étudiés sous leur forme entière ou mature. Ainsi, la caractérisation de leur affinité pour les phospholipides, associée à leur modélisation tridimensionnelle, ont permis de démontrer que les différences de régulation par le Ca2+, observées entre les formes entières et mature, provenait de la présence d'une hélice a amphipathique, retirée lors du processus de maturation. Le second axe concerne le développement d'une nouvelle méthode de mesure des activités PLD via le dosage de manière direct, spécifique et continu du PA grâce à la propriété d'amplification de fluorescence par chélation de la 8-hydroxyquinoléine, en présence de Ca2+. Ainsi, ce test apparait adapté pour le suivi de l'inhibition des PLDs et pour l'étude de leur spécificité de substrat, en utilisant des phospholipides naturels avec différentes tête polaires, et à l'échelle d'une microplaque

Phospholipase D (PLD) hydrolyses membrane phospholipids, leading to the formation of free polar headgroup and phosphatidic acid releasing, involved in cell signaling. To understand the biochemical properties of PLDs, this work has been made around two axes. The one first concerns the recombinant expression and purification of the PLDa of Arabidopsis thaliana (AtPLDa) in the yeast Pichia pastoris. The N-terminal sequence of the recombinant AtPLDa has been determined and found to lack its first 35 amino acids, suggesting the involvement of a maturing mechanism. However, plant PLDs exhibit a C2-lipid binding domain at their N-terminal region, which is involved in their Ca2+-dependent membrane targeting. Thus, to assess the impact of such a cleavage, whole and mature-like C2 domains of AtPLDa, as well as of AtPLDß, for the sake of comparison were studied. Thus, the characterization of their affinity for phospholipids, combined with their three-dimensional modeling have demonstrated that the differences observed in their regulation by Ca2+, observed between whole and mature-like forms, originated from the presence of a N-terminus amphipathic a helix, removed during the maturation process. The second axis concerns the development of a novel PLD assay that measure PA in a direct, specific and…

Advisors/Committee Members: Abousalham, Abdelkarim (thesis director), Noiriel, Alexandre (thesis director).

Subjects/Keywords: Phospholipases D; Domaine C2; Arabidopsis thaliana; Pichia pastoris; 8-Hydroxyquinoléine; Phospholipase D; C2 domains; Arabidopsis thaliana; Pichia pastoris; 8-hydroxyquinoline; 572

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Rahier-Corticchiato, R. (2016). Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities. (Doctoral Dissertation). Lyon. Retrieved from http://www.theses.fr/2016LYSE1292

Chicago Manual of Style (16th Edition):

Rahier-Corticchiato, Renaud. “Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities.” 2016. Doctoral Dissertation, Lyon. Accessed October 23, 2017. http://www.theses.fr/2016LYSE1292.

MLA Handbook (7th Edition):

Rahier-Corticchiato, Renaud. “Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities.” 2016. Web. 23 Oct 2017.

Vancouver:

Rahier-Corticchiato R. Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities. [Internet] [Doctoral dissertation]. Lyon; 2016. [cited 2017 Oct 23]. Available from: http://www.theses.fr/2016LYSE1292.

Council of Science Editors:

Rahier-Corticchiato R. Caractérisation biochimique des phospholipases D et de leurs domaines fonctionnels : nouvelle méthode de mesure de l’activité phospholipase D : Biochemical characterization of phospholipases D and their functional domains : novel method for measuring phospholipase D activities. [Doctoral Dissertation]. Lyon; 2016. Available from: http://www.theses.fr/2016LYSE1292

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