subject:(3T3 L1 cells)

Lithuanian Veterinary Academy

1. Adomkienė, Rasa. Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse.

Degree: PhD, Zootechny, 2009, Lithuanian Veterinary Academy

URL: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20091223_134641-94789 ;

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Bjorn pademonstruotas ClRR pernešimas į jūros gyvūnų mitybos grandinę, leidžia tikėtis, jog ir žmogaus organizmas gali įsisavinti chlorintas riebalų rūgštis valgant žuvį ir galbūt netgi… (more)

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Bjorn pademonstruotas ClRR pernešimas į jūros gyvūnų mitybos grandinę, leidžia tikėtis, jog ir žmogaus organizmas gali įsisavinti chlorintas riebalų rūgštis valgant žuvį ir galbūt netgi chloru apdorotus maisto produktus ar geriant chlorintą vandenį. Tuo tarpu, kol kas tik su dviejų rūšių žmogaus ląstelėmis, atlikti tyrimai, prieštarauja šiai hipotezei. Šiuo metu yra tirtas tik chlorintos stearino rūgšties įsisavinimas žarnų epitelio INT 407 ir neuroblastomos SH-SY5Y ląstelėse. Pasaulinėje literatūroje nėra duomenų apie kitų ląstelių: tiek žmonių, tiek gyvūnų, sugebėjimą įsisavinti ar kaupti chlorintas riebalų rūgštis. Pirmą kartą chlorintų riebalų rūgščių įsisavinimo tyrimas atliktas su HepG2 ir 3T3-L1 ląstelėmis. Rezultatai parodė, jog ląstelės iš maitinimo terpės įsisavina chlorintas riebalų rūgštis, tačiau labai sparčiai jas metabolizuoja. Hepatomos ląstelės įterpė 34 ir 41 proc. didesnį (P<0,05) kiekį chlorintos stearino ir palmitino rūgšties nei pelių preadipocitai. HepG2 ląstelės įsisavino daugiau nei pusę, t.y. 61 proc. chlorintos palmitino rūgšties kiekio nuo pirminės šios RR koncentracijos maitinimo terpėje, kitą dalį (34 %) per 12 h inkubacijos periodą metabolizavo, o terpėje Cl2RR liko tik pėdsakai. Taip pat pirmą kartą HepG2 ląstelės inkubuotos terpėje su 9,10-heksachlortristearoilgliceroliu. Nei ląstelėse, nei maitinimo terpėje chlorintos stearino ir kitų chlorintų riebalų rūgščių nenustatyta bei nenustatyta ir įtaka kitų ne chlorintų riebalų rūgščių... [toliau žr. visą tekstą]

Chlorinated fatty acids (ClFAs) represent a major part of the total extractable chlorinated organic compounds found in fish and other marine biota. Although ClFAs have been found in fish and marine mammals for many years, there is still lack of information about there influence on live organisms, impact on cells and bioaccumulation. Recently the analysis of the embedding of the chlorinated fatty acids into mammalian cells and its impact on the physiological processes had become a hot topic, ever since the medics had recommended for the people keen on taking care of their health to use more sea and fish products, especially because of the omega-3 fatty acids found in fish composition. ClFAs have been detected both naturally occurring in biota and formed in aquatic animals because of environmental pollution from pulp bleach mills. Furthermore ClFAs have been detected in several alimentary products. The way ClFAs get in organism and their possible accumulation are not sufficiently researched yet ClFAs have been shown to influence reproduction processes and induce disturbances of cells. Despite adverse effects ClFAs are not recognized by tissues as xenobiotic and are not eliminated from organism. The incorporation and metabolism of dichloro palmitic and dichloro stearic acids in HepG2 and 3T3-L1 cell-lines were studied. Investigation showed that HepG2 and 3T3-L1 cells uptake chlorinated fatty acids from cell culture medium, however they metabolize them fast. 9,10-dichloro... [to full text]

Advisors/Committee Members: Stankevičienė, Marija (Doctoral dissertation supervisor), Stankevičius, Henrikas (Doctoral dissertation advisor), Bakutis, Bronius (Doctoral dissertation committee chair), Garmienė, Galina (Doctoral dissertation committee member), Gružauskas, Romas (Doctoral dissertation committee member), Sederevičius, Antanas (Doctoral dissertation committee member), Šarkinas, Antanas (Doctoral dissertation committee member), Juozaitienė, Vida (Doctoral dissertation opponent), Senikienė, Žibuoklė (Doctoral dissertation opponent).

Subjects/Keywords: Chlorintos riebalų rūgštys; Aplinkos tarša; HepG2 ląstelės; 3T3-L1 ląstelės; Chlorinated fatty acids; Environmental pollution; HepG2 cells; 3T3-L1 cells

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Adomkienė, R. (2009). Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse. (Doctoral Dissertation). Lithuanian Veterinary Academy. Retrieved from http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20091223_134641-94789 ;

Chicago Manual of Style (16^th Edition):

Adomkienė, Rasa. “Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse.” 2009. Doctoral Dissertation, Lithuanian Veterinary Academy. Accessed January 16, 2021. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20091223_134641-94789 ;.

MLA Handbook (7^th Edition):

Adomkienė, Rasa. “Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse.” 2009. Web. 16 Jan 2021.

Vancouver:

Adomkienė R. Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse. [Internet] [Doctoral dissertation]. Lithuanian Veterinary Academy; 2009. [cited 2021 Jan 16]. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20091223_134641-94789 ;.

Council of Science Editors:

Adomkienė R. Būtinųjų ir chlorintų riebalų rūgščių kiekio kitimo dinamika HepG2 ir 3T3-L1 linijų ląstelėse. [Doctoral Dissertation]. Lithuanian Veterinary Academy; 2009. Available from: http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2009~D_20091223_134641-94789 ;

Mississippi State University

2. Song, Jie. Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network.

Degree: PhD, Biochemistry, Molecular Biology, Entomology and Plant Pathology, 2014, Mississippi State University

URL: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10152014-032027/ ;

► Abscisic acid is an important plant hormone in the responses to biotic and abiotic stresses, which also regulates various growth and developmental processes in… (more)

▼ Abscisic acid is an important plant hormone in the responses to biotic and abiotic stresses, which also regulates various growth and developmental processes in plants. Three major components-receptors (PYRs), the PP2C type phosphatases and the SnRK2 subtype kinases form a double negative regulatory system: PYR/PYL/RCARs inhibit the activity of PP2Cs while PP2Cs inhibit that of SnRK2s in ABA signaling pathway. The results of my studies showed that ABA would directly affect the interaction between SnRK2.2 and ABI1 in absence of PYRs. Furthermore, ABA can inhibit the catalytic activity of the SnRK2.2 kinase. These findings indicated that ABA may directly interact with SnRK2.2. Posttranslational modifications play a key role in signal transduction. Phosphorylation is the most important posttranscriptional modification in ABA signal transduction. To dissect new components in ABA signaling network in plants, proteomics studies were carried out in Arabidopsis for identifying ABA- responsive phosphoproteins. Ten phosphoproteins, ATPB, ATPC1, FBA1, CTIMC, GGAT1, GAPC1, GAPC2, GAPA1 and ALDH11A3, were identified by 2-DE proteomic approach and LC-MS/MS analysis. These proteins are likely to be the potential phosphorylated targets of SnRK2s in ABA signaling network. Lysine acetylation (LysAc) also emerges as one of the important posttranslational modifications for protein regulation in plants. Eleven lysine acetylated proteins with altered acetylation in response to ABA were identified in Arabidopsis using proteomic approach. The increased LysAc of Rubisco and the decreased Rubisco activity by ABA treatment indicates the acetylation of Rubisco caused by ABA resulted in the inhibition of Rubisco activity. ABA has also been shown to exist and function in both lower animals and mammalians. The medical application of ABA has become a new area of investigation. To explore the role of protein phosphorylation in ABA-mediated function in mammalians, phosphoproteomic study was conducted in mouse 3T3-L1 cells. Ten phosphoproteins with significant changes in serine/threonine phosphorylation in response to ABA were identified. These results suggest these phosphoproteins are involved in ABA signaling network in mouse cells. The significance of the function of SFRS1, ANXA1 and Galectin-3 on human diseases indicated that ABA could be a potential treatment for some human diseases, such as cancer. Advisors/Committee Members: Jiaxu Li (chair), Din-Pow Ma (committee member), Zhaohua Peng (committee member), Daniel G. Peterson (committee member), Scott T. Willard (committee member).

Subjects/Keywords: ABACABA signaling pathway; Arabidopsis; proteomics; phosphorylation; acetylation; 3T3-L1 mouse cells

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Song, J. (2014). Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network. (Doctoral Dissertation). Mississippi State University. Retrieved from http://sun.library.msstate.edu/ETD-db/theses/available/etd-10152014-032027/ ;

Chicago Manual of Style (16^th Edition):

Song, Jie. “Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network.” 2014. Doctoral Dissertation, Mississippi State University. Accessed January 16, 2021. http://sun.library.msstate.edu/ETD-db/theses/available/etd-10152014-032027/ ;.

MLA Handbook (7^th Edition):

Song, Jie. “Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network.” 2014. Web. 16 Jan 2021.

Vancouver:

Song J. Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network. [Internet] [Doctoral dissertation]. Mississippi State University; 2014. [cited 2021 Jan 16]. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10152014-032027/ ;.

Council of Science Editors:

Song J. Molecular and proteomic analysis of components involved in abscisic acid (ABA) signaling network. [Doctoral Dissertation]. Mississippi State University; 2014. Available from: http://sun.library.msstate.edu/ETD-db/theses/available/etd-10152014-032027/ ;

East Carolina University

3. Sellers, Samantha Sue. A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS.

Degree: PhD, PHD-Anatomy and Cell Biology, 2017, East Carolina University

URL: http://hdl.handle.net/10342/6366

► During embryogenesis, mesenchymal progenitor cells exhibit hyaluronan-dependent pericellular matrices as a major component of the extracellular matrix. As connective tissues form by cellular condensations, there… (more)

▼ During embryogenesis, mesenchymal progenitor cells exhibit hyaluronan-dependent pericellular matrices as a major component of the extracellular matrix. As connective tissues form by cellular condensations, there is a loss of cell-associated hyaluronan to facilitate cell-to-cell adhesion. The goal of this dissertation is to gain insight into how hyaluronan-associated components of the extracellular/pericellular matrix participate in directing differentiation fates of mesenchymal cells. This work began with attempts to isolate and study a primary mesenchymal progenitor population from adult bovine articular cartilage and progressed to the use of the adipocyte-favoring mesenchymal progenitor cell line, 3T3-L1. A particle exclusion assay revealed that 3T3-L1 mesenchymal cells exhibited large hyaluronan-dependent pericellular matrices that were displaced by small hyaluronan fragments consisting of 6-8 disaccharides, suggesting retention of the matrix by a cell surface receptor. These pericellular matrices were enhanced with the addition of exogenous aggrecan (prepared from bovine articular cartilage). However, 3T3-L1 cells lost the ability to synthesize or retain a hyaluronan-dependent pericellular matrix during adipogenesis. We observed a reduction in mRNA and protein expression of CD44, the hyaluronan receptor that anchors the pericellular matrix to the cell surface, during adipogenesis, in addition to a reduction in mRNA expression of Has2 and Vcan. These reductions in pericellular matrix components are likely responsible for the loss of detectable pericellular matrix by 3T3-L1 adipocytes. The importance of CD44's role in pericellular matrix retention was further supported when pericellular matrices could not be formed by 3T3-L1 adipocytes even when exogenous hyaluronan and aggrecan were supplied. Hyaluronan was visualized by staining with a binding protein (HABP) and fluorescent microscopy. Mesenchymal cells exhibited bright cell surface HABP staining whereas adipocytes stained only weakly. However, when the adipocytes were permeabilized with 0.5% Triton-X, hyaluronan was revealed between the lipid droplets of these cells suggesting receptor-mediated endocytosis. When hyaluronan synthesis was blocked with 4-methylumbelliferone, adipogenesis of 3T3-L1 cells was significantly inhibited. Additionally, exogenous aggrecan added to the culture medium during the adipogenic differentiation protocol significantly inhibited adipogenesis. Collectively, these data suggest that 3T3-L1 adipogenesis is dependent upon the temporal regulation of hyaluronan. Advisors/Committee Members: Knudson, Cheryl B. (advisor).

Subjects/Keywords: 3T3-L1 cells; aggrecan; extracellular matrix; Hyaluronic Acid; Adipogenesis; Cartilage, Articular; Stem Cells

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sellers, S. S. (2017). A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS. (Doctoral Dissertation). East Carolina University. Retrieved from http://hdl.handle.net/10342/6366

Chicago Manual of Style (16^th Edition):

Sellers, Samantha Sue. “A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS.” 2017. Doctoral Dissertation, East Carolina University. Accessed January 16, 2021. http://hdl.handle.net/10342/6366.

MLA Handbook (7^th Edition):

Sellers, Samantha Sue. “A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS.” 2017. Web. 16 Jan 2021.

Vancouver:

Sellers SS. A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS. [Internet] [Doctoral dissertation]. East Carolina University; 2017. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/10342/6366.

Council of Science Editors:

Sellers SS. A QUEST FOR ARTICULAR CARTILAGE PROGENITOR CELLS LEADS TO TEMPORAL REGULATION OF HYALURONAN REQUIRED FOR 3T3-L1 ADIPOGENESIS. [Doctoral Dissertation]. East Carolina University; 2017. Available from: http://hdl.handle.net/10342/6366

Georgia State University

4. Chen, Yii-Shyuan. Role of DNA Methylation in Adipogenesis.

Degree: MS, Biology, 2014, Georgia State University

URL: https://scholarworks.gsu.edu/biology_theses/57

► The increase in the prevalence of obesity and obesity-related diseases has caused greater attention to be placed on the molecular mechanisms controlling adipogenesis. In… (more)

Subjects/Keywords: Adipogenesis; DNA Methylation; Osteoblastogenesis; ST2 Cells; Wnt10a; Wnt signaling inhibitor; 3T3-L1 Cells

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chen, Y. (2014). Role of DNA Methylation in Adipogenesis. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/biology_theses/57

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chen, Yii-Shyuan. “Role of DNA Methylation in Adipogenesis.” 2014. Thesis, Georgia State University. Accessed January 16, 2021. https://scholarworks.gsu.edu/biology_theses/57.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chen, Yii-Shyuan. “Role of DNA Methylation in Adipogenesis.” 2014. Web. 16 Jan 2021.

Vancouver:

Chen Y. Role of DNA Methylation in Adipogenesis. [Internet] [Thesis]. Georgia State University; 2014. [cited 2021 Jan 16]. Available from: https://scholarworks.gsu.edu/biology_theses/57.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chen Y. Role of DNA Methylation in Adipogenesis. [Thesis]. Georgia State University; 2014. Available from: https://scholarworks.gsu.edu/biology_theses/57

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McMaster University

5. Josan, Chitmandeep. Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells.

Degree: MSc, 2018, McMaster University

URL: http://hdl.handle.net/11375/23716

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Studying molecular mechanisms underlying adipocyte differentiation is imperative to understanding adipocyte function and its role in obesity. However, the majority of research exploring adipogenesis is… (more)

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Studying molecular mechanisms underlying adipocyte differentiation is imperative to understanding adipocyte function and its role in obesity. However, the majority of research exploring adipogenesis is conducted with cell lines cultured directly on tissue culture plastic. Culturing cells on plastic may result in altered proliferation and differentiation, and subsequent change in pharmacological response. The extracellular matrix (ECM) plays a critical role in adipocyte development and survival. It is suggested that cells in vitro express high levels of ECM proteins to compensate for lack of an ECM. Differentiating preadipocytes on a substrate representative of the mature adipocyte extracellular environment may provide a more physiological response to drugs and environmental chemicals. The purpose of this study was to investigate the impact of Matrigel on 3T3-L1 cell growth, differentiation, lipid accumulation and responsiveness to Rosiglitazone. Matrigel decreased 3T3-L1 cell proliferation, enhanced lipid accumulation, and increased expression of adipogenic and lipogenic markers, including PPARγ, C/EBPα, SREBP1c, FAS, LPL, FABP4 and PLIN1. This was accompanied by a decrease in gene expression of ECM proteins, including fibronectin, collagen 1, collagen 3, collagen 4, laminin and collagen 6 in 3T3-L1 cells on Matrigel. Finally, Matrigel enhanced the response of 3T3-L1 cells to Rosiglitazone, which is a known PPARγ agonist and significantly increases lipid accumulation in 3T3-L1 cells. Our results suggest that enhanced lipid accumulation in 3T3-L1 cells on Matrigel is associated with decreased expression of ECM genes. Future studies require investigation of the cell-to-ECM interaction to confirm these findings. This study proposes that the nature of the ECM for cultured adipocytes alters temporal lipid accumulation patterns and response to various drugs as compared to 3T3-L1 cells grown on tissue culture plastic.

Thesis

Master of Science (MSc)

Advisors/Committee Members: Raha, Sandeep, Medical Sciences.

Subjects/Keywords: White adipose tissue; Obesity; Extracellular Matrix; Matrigel; Adipogenesis; Adipocyte differentiation; 3T3-L1 cells

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Josan, C. (2018). Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells. (Masters Thesis). McMaster University. Retrieved from http://hdl.handle.net/11375/23716

Chicago Manual of Style (16^th Edition):

Josan, Chitmandeep. “Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells.” 2018. Masters Thesis, McMaster University. Accessed January 16, 2021. http://hdl.handle.net/11375/23716.

MLA Handbook (7^th Edition):

Josan, Chitmandeep. “Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells.” 2018. Web. 16 Jan 2021.

Vancouver:

Josan C. Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells. [Internet] [Masters thesis]. McMaster University; 2018. [cited 2021 Jan 16]. Available from: http://hdl.handle.net/11375/23716.

Council of Science Editors:

Josan C. Matrigel alters the expression of genes related to adipogenesis and the production of extracellular matrix in 3T3-L1 cells. [Masters Thesis]. McMaster University; 2018. Available from: http://hdl.handle.net/11375/23716

6. Dingels, Nicole Katherine. Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells.

Degree: MS, Nutrition, 2012, Georgia State University

URL: https://scholarworks.gsu.edu/nutrition_theses/40

► Background: The typical western diet contains foods with modest amounts of lipid oxidation products. Previous work by us and others have demonstrated that mildly… (more)

▼ Background: The typical western diet contains foods with modest amounts of lipid oxidation products. Previous work by us and others have demonstrated that mildly oxidized lipids promote a gain in fat mass while highly oxidized lipids decrease fat mass in rodents and triglyceride (TAG) accumulation in 3T3-L1 cells. Adipocyte differentiation is regulated by a key nuclear transcription factor known as PPARγ. Objective: To investigate if the alterations in triglyceride accumulation in 3T3-L1 cells pretreated with oxidized soy oil are due to 1) a change in PPARg DNA interactions 2) changes in the expression of SREBP-1c, PPARg, and/or its target genes. Main Methods: Confluent 3T3-L1 cells were pretreated for 24hours with 0.01% soy oil (SO) which was either unheated (unheated SO) or heated for 3, (3h-SO), 6 (6h-SO), or 9hours (9h-SO). The effect of 24hour soy oil exposure was assessed at several time points throughout the differentiation process. Alterations in PPARg DNA interaction was assessed using a PPARγ transcription factor assay kit while alterations in the expression of genes upstream and downstream of PPARγ was determined by RT-PCR. Primary and secondary products of oxidation within the SO were determined by spectrophotometry. Results: The 6hr-SO contained the greatest concentration of peroxides whereas both the 6hr-SO and 9hr-SO contained a significantly higher concentration of conjugated dienes and aldehydes.Nuclear extracts from 3T3-L1 cells pretreated with 6h-SO demonstrated the greatest reduction in PPARγ DNA binding. Compared to the unheated SO and mildly oxidized 3h-SO, cells treated with the 6h-SO had a significant reduction in SREBP-1c, PPARg, LPL, and GLUT4 expression occurring early in the differentiation process. Variations in the gene expression of 6hr-SO pretreated cells persisted within partially differentiated and mature adipocytes. Conclusions: Pre-treatment of preadipocytes with soy oil heated for ³ 6h greatly decreases the activity of PPARγ in the nucleus and adipogenic gene expression . These changes seen in early differentiation seem to correlate the best with the phenotype of reduced triglyceride accumulation seen in mature adipocytes. Advisors/Committee Members: Meera Penumetcha, Nalini Santanam, Barbara Hopkins.

Subjects/Keywords: PPAR gamma; oxidized lipids; gene expression; adipocyte differentiation; triglyceride accumulation; 3T3-L1 cells

…untreated 3T3-L1 cells 23 4 PPARγ transcription factor binding in nuclear extracts from 3T3-L1… …previously demonstrated a noteworthy interaction between TAG accumulation within 3T3-L1 cells and… …of 3T3-L1 cells exposed to unheated and mildly oxidized soy oil was unaltered. Oxidized… …accumulation in 3T3-L1 cells mediated by oxidized soy oil are due to 1) a change in the ability… …within 3T3-L1 PPARγ knockout cells based on their inability to differentiate after exposure to…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dingels, N. K. (2012). Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells. (Thesis). Georgia State University. Retrieved from https://scholarworks.gsu.edu/nutrition_theses/40

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dingels, Nicole Katherine. “Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells.” 2012. Thesis, Georgia State University. Accessed January 16, 2021. https://scholarworks.gsu.edu/nutrition_theses/40.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dingels, Nicole Katherine. “Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells.” 2012. Web. 16 Jan 2021.

Vancouver:

Dingels NK. Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells. [Internet] [Thesis]. Georgia State University; 2012. [cited 2021 Jan 16]. Available from: https://scholarworks.gsu.edu/nutrition_theses/40.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dingels NK. Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells. [Thesis]. Georgia State University; 2012. Available from: https://scholarworks.gsu.edu/nutrition_theses/40

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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