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You searched for subject:(1 4 anthraquinone). Showing records 1 – 3 of 3 total matches.

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Utah State University

1. Shrestha, Jaya P. Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents.

Degree: PhD, Chemistry and Biochemistry, 2016, Utah State University

Synthesizing bioactive small molecules by structural modification of 1,4-naphthoquinone was the primary goal of this research. Several bioactive compounds with anticancer, antifungal, and antibacterial activities were synthesized. All the synthetic protocols were optimized in such ways that do not require cumbersome purification. First, a new protocol for the synthesis of NQM111 was developed. NQM111 is a highly potent anticancer agent developed in our laboratory, but the old protocol does not provide enough quantity for in vivo study. Therefore, a new safe and improved method was developed which provides enough quantity for in vivo study. The second project involves the synthesis of 1,4-naphthoquinone conjugated with an aromatic group. These compounds are a highly potent anticancer agent with ~8-fold selectivity towards cancer cell lines than the non-cancer cell line. A mode of action study of this compound was identified, and it was observed that these compounds generate reactive oxygen species,which triggers apoptosis. The final project involves the synthesis of 1,4-naphthoquinone based antifungal, and antibacterial compounds. These compounds are multi-cationic in nature with a hydrophobic tail. Six different analogs with varying hydrophobic tails were synthesized and tested for their antibacterial and antifungal activity. These compounds showed excellent activity against wide range of fungi including resistant strains. Advisors/Committee Members: Cheng-Wei Tom Chang, ;.

Subjects/Keywords: 1; 4-Naphthoquinone; Anthraquinone; Antibiotics; Anticancer; Antifungal; Triazole; Chemistry

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APA (6th Edition):

Shrestha, J. P. (2016). Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents. (Doctoral Dissertation). Utah State University. Retrieved from https://digitalcommons.usu.edu/etd/4925

Chicago Manual of Style (16th Edition):

Shrestha, Jaya P. “Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents.” 2016. Doctoral Dissertation, Utah State University. Accessed December 15, 2019. https://digitalcommons.usu.edu/etd/4925.

MLA Handbook (7th Edition):

Shrestha, Jaya P. “Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents.” 2016. Web. 15 Dec 2019.

Vancouver:

Shrestha JP. Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents. [Internet] [Doctoral dissertation]. Utah State University; 2016. [cited 2019 Dec 15]. Available from: https://digitalcommons.usu.edu/etd/4925.

Council of Science Editors:

Shrestha JP. Synthesis, Structure-Activity Relationship Study, and Mode of Action Study of 1,4-Naphthoquinone Based Anticancer and Antimicrobial Agents. [Doctoral Dissertation]. Utah State University; 2016. Available from: https://digitalcommons.usu.edu/etd/4925


NSYSU

2. Tsai, Chia-jung. Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone.

Degree: Master, Chemistry, 2015, NSYSU

Poly(4-(bicycle[2.2.1]hept-1-en-4-yl)-anthraquinone), PBHEAQ, has been polymerized by ring opening metathesis polymerization, and the electrochemical properties of the polymer are studied. The 4-(bicycle[2.2.1]hept-1-en-4-yl)- anthraquinone (BHEAQ) monomer is synthesized by Heck reaction. Various carbon materials were mixed with the PBHEAQ polymer to fabricate PBHEAQ/carbon composite electrodes using slurry coating. The carbon materials are graphene, Super P, and carbon nanotubes. The electrochemical properties of the Li|PBHEAQ cell are investigated by cyclic voltammetry (CV), charge-discharge measurements, and cycle-life tests. The CV results show a redox couple at 2.0-2.5 V vs. Li/Li+. The charge-discharge result show that the energy capacity of the PBHEAQ is 110 mAh/g. Furthermore, the cycle-life results show that the cells having promising cyclability. Advisors/Committee Members: Chun-hu Chen (chair), Mao-Sung Wu (chair), Jyh-Tsung Lee (committee member).

Subjects/Keywords: organic batteries; ring opening metathesis polymerization; poly(4-(bicycle[2.2.1]hept-1-en-4-yl)-anthraquinone); rechargeable

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Tsai, C. (2015). Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0620115-153801

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Tsai, Chia-jung. “Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone.” 2015. Thesis, NSYSU. Accessed December 15, 2019. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0620115-153801.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Tsai, Chia-jung. “Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone.” 2015. Web. 15 Dec 2019.

Vancouver:

Tsai C. Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone. [Internet] [Thesis]. NSYSU; 2015. [cited 2019 Dec 15]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0620115-153801.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tsai C. Synthesis and Electrochemical Studies of Poly(4-(bicyclo[2.2.1]hept-1-en-4-yl)-anthraquinone. [Thesis]. NSYSU; 2015. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0620115-153801

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Aboytes, Peter. Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone.

Degree: 1959, North Texas State College

The purpose of this investigation was the synthesis of some 1,4-naphthoquinones and 1,4-anthraquinones. It will be shown that some of these substituted quinones exhibit physiological properties. Advisors/Committee Members: Truitt, Price, York, Carl T..

Subjects/Keywords: 1, 4-naphthoquinone; 1,4-anthraquinone; chemistry; Naphthoquinone  – Derivatives.; Anthraquinones  – Derivatives.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Aboytes, P. (1959). Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone. (Thesis). North Texas State College. Retrieved from https://digital.library.unt.edu/ark:/67531/metadc108043/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Aboytes, Peter. “Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone.” 1959. Thesis, North Texas State College. Accessed December 15, 2019. https://digital.library.unt.edu/ark:/67531/metadc108043/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Aboytes, Peter. “Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone.” 1959. Web. 15 Dec 2019.

Vancouver:

Aboytes P. Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone. [Internet] [Thesis]. North Texas State College; 1959. [cited 2019 Dec 15]. Available from: https://digital.library.unt.edu/ark:/67531/metadc108043/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Aboytes P. Derivatives of 1,4-Naphthoquinone and 1,4-Anthraquinone. [Thesis]. North Texas State College; 1959. Available from: https://digital.library.unt.edu/ark:/67531/metadc108043/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.