subject:( conjugated linoleic acid)

University of Manitoba

1. DeClercq, Vanessa. The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function.

Degree: Food Science, 2010, University of Manitoba

URL: http://hdl.handle.net/1993/4085

► Enlargement of adipocytes in obesity leads to alteration in adipokine production and these changes are linked to the development of obesity-related cardiovascular diseases. Adipokines specifically… (more)

▼ Enlargement of adipocytes in obesity leads to alteration in adipokine production and these changes are linked to the development of obesity-related cardiovascular diseases. Adipokines specifically associated with obesity-related hypertension include angiotensinogen and adiponectin. Conjugated linoleic acid (CLA) has been reported to reduce blood pressure in obese insulin-resistant rats, but its mechanism of action has not been identified. The objective of this study was to determine whether CLA’s ability to improve obesity-related hypertension involves reducing adipocyte size and altering adipokine production. Fa/fa Zucker rats (6 or 16 week old) were fed diets containing CLA isomers for 8 weeks. The trans(t)10,cis(c)12-CLA isomer reduced adipocyte size in both younger and older rats. Despite beneficial changes in cell size of rats fed the t10,c12-CLA isomer, there were no changes in the renin-angiotensin system or pro-inflammatory cytokines such as tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 or the anti-inflammatory cytokine IL-10. In contrast, the t10,c12-CLA isomer increased adiponectin levels both in the circulation and in adipose tissue. This was associated with increased phosphorylation of endothelial nitric oxide synthase (eNOS) in adipose tissue and aorta. Direct treatment of CLA isomers in cultured endothelial cells did not increase eNOS phosphorylation but increases were observed with adiponectin treatment. In vivo, infusion with adiponectin increased eNOS phosphorylation in adipose of fa/fa Zucker rats in parallel with improvements in blood pressure. Similarly, when circulating levels of adiponectin increased in rats fed the t10,c12-CLA isomer diet, blood pressure was also attenuated. In younger rats, both the t10-c12 and c9,t11-CLA isomers were significantly different from the control group at week 8, however, only the t10,c12-CLA isomer was comparable to the commonly used anti-hypertensive medication captopril. In conclusion, the beneficial effects of the t10,c12-CLA isomer on blood pressure may in part be due to its ability to reduce the number of large adipocytes in vivo, thus increasing the production of adiponectin which subsequently activates vascular eNOS. Advisors/Committee Members: Zahradka, Peter (Human Nutritional Sciences), Aukema, Harold (Human Nutritional Sciences).

Subjects/Keywords: obesity; hypertension; conjugated linoleic acid; adipocyte; adipokines

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

DeClercq, V. (2010). The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/4085

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

DeClercq, Vanessa. “The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function.” 2010. Thesis, University of Manitoba. Accessed March 07, 2021. http://hdl.handle.net/1993/4085.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

DeClercq, Vanessa. “The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function.” 2010. Web. 07 Mar 2021.

Vancouver:

DeClercq V. The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function. [Internet] [Thesis]. University of Manitoba; 2010. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1993/4085.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

DeClercq V. The effects of conjugated linoleic acid (CLA) isomers on obesity-related hypertension: insight into possible mechanisms involving adipocyte function. [Thesis]. University of Manitoba; 2010. Available from: http://hdl.handle.net/1993/4085

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

2. Wadowski, Michael C. Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System.

Degree: MS, Department of Agricultural, Food, and Nutritional Science, 2012, University of Alberta

URL: https://era.library.ualberta.ca/files/zg64tm31z

► Obesity is a major risk factor for the development of type 2 diabetes (T2D). While altered systemic inflammation is associated with the development T2D, the… (more)

▼ Obesity is a major risk factor for the development of type 2 diabetes (T2D). While altered systemic inflammation is associated with the development T2D, the effects of obesity on immune function are not well known. It is not known why some obese individuals develop T2D, and some remain healthy. Dietary components may result in inflammation; relationships between industrially-produced trans fatty acids and inflammation have been established but there is a lack of research focusing on the effects of ruminant-derived trans fatty acids (conjugated linoleic acid (CLA) and vaccenic acid (VA)). The purpose of this study is to compare peripheral immune cell types and function between healthy obese and diabetic obese subjects, and to examine the effect of ruminant-derived trans fats on cytokine expression in adipose tissue of obese rats. Peripheral blood was obtained from healthy obese (n=10) and diabetic obese (n=9) subjects. Immune cell phenotypes were determined by flow cytometry. T cell proportions were not different between healthy obese and diabetic obese subject; however, diabetic obese subjects had a significantly higher (p<0.05) percentage of CD71-expressing T cells compared with healthy obese subjects. Diabetic subjects also had a significantly higher percentage of regulatory and naïve T cells. After stimulating with the polyclonal T cell mitogen phytohemagglutinin, cells from diabetic obese subjects produced less (P<0.05) IL-6 and TNF-α; IL-2 did not differ between the groups. Obese JCR:LA-cp rats (n=20) were fed a control, VA or CLA diet for 8 weeks. Perirenal fat pads were extracted and cytokine expression measured by qRT-PCR. Obese rats had higher expression (p<0.05) of TGF-β, IL-6, and IL-12 in adipose tissue compared to lean rats. Obese rats fed CLA had higher IL-6 expression in adipose tissue compared with rats fed the VA diet. These results suggest that when T2D accompanies obesity, T cell and neutrophil dysfunction occurs. Furthermore, naturally occurring trans fatty acids do not appear to exacerbate the production of cytokines in obese rats.

Subjects/Keywords: Type 2 Diabetes; Vaccenic Acid; Obesity; Conjugated Linoleic Acid; Immune System

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wadowski, M. C. (2012). Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/zg64tm31z

Chicago Manual of Style (16^th Edition):

Wadowski, Michael C. “Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System.” 2012. Masters Thesis, University of Alberta. Accessed March 07, 2021. https://era.library.ualberta.ca/files/zg64tm31z.

MLA Handbook (7^th Edition):

Wadowski, Michael C. “Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System.” 2012. Web. 07 Mar 2021.

Vancouver:

Wadowski MC. Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System. [Internet] [Masters thesis]. University of Alberta; 2012. [cited 2021 Mar 07]. Available from: https://era.library.ualberta.ca/files/zg64tm31z.

Council of Science Editors:

Wadowski MC. Effects of Trans Fats, Obesity, and Type 2 Diabetes on the Immune System. [Masters Thesis]. University of Alberta; 2012. Available from: https://era.library.ualberta.ca/files/zg64tm31z

Univerzitet u Beogradu

3. Pantić, Srđan M., 1985-. Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu.

Degree: Fakultet veterinarske medicine, 2016, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:10464/bdef:Content/get

►

Veterinarska medicina - Higijena i tehnologija mesa / Veterinary medicine - Hygiene and Meat Technology

Osnovni cilj istraživanja u okviru ove doktorske disertacije je bio… (more)

▼

Veterinarska medicina - Higijena i tehnologija mesa / Veterinary medicine - Hygiene and Meat Technology

Osnovni cilj istraživanja u okviru ove doktorske disertacije je bio ispitivanje efekata primene CLA na proizvodne rezultate svinja u tovu (dnevna potrošnja hrane, dnevni prirast, konverzija). Od posebnog značaja su rezultati uticaja CLA na parametre prinosa mesa (debljina leđne slanine, procenat mesa u trupu, količina mesa u trupu), parametre kvaliteta mesa (hemijski i masnokiselinski sastav, pH, mramoriranost, boja, senzorne osobine) i proizvoda od mesa kao što su fermentisane kobasice, hladno dimljeni vrat i hladno dimljena slanina. Stoga ispitivanja u okviru ove doktorske disertacije ukazuju i na uticaj CLA u ishrani svinja na parametre kvaliteta odabranih proizvoda od mesa. Za ogled su korištene svinje od majki meleza jorkšira i landrasa, a oca durok, sa početnom telesnom masom od 60 kg. Svinje su podeljene u dve ogledne grupe od po 20 svinja i hranjene standardnom smešom (NRC, 1998) za završni tov svinja od 60-100 kg (finišer), s tim što su se grupe razlikovale jedino u tome što je ogledna grupa imala u obroku preparat Lutalin ® proizvođača BASF (Nemačka), u količini od 2% u smeši. Za ispitivanja su korišćene standardne i priznate metode. Utvrđene su statistički značajne razlike između prosečnih sadržaja zasićenih, mononezasićenih, polinezasićenih, n-3 i n-6 masnih kiselina u hrani za svinje. Utvrđena je statistički značajna razlika između odnosa n-3 i n-6 masnih kiselina. Prosečan ukupan sadržaj konjugovane linolne kiseline u smeši za ishranu ogledne grupe svinja bio je 5,12±0,01%. U hrani za kontrolnu grupu svinja nije utvrđeno prisustvo konjugovane linolne kiseline.Nisu utvrđene statistički značajne razlike između prosečne dnevne potrošnje hrane, dnevnog prirasta i konzumacije hrane između kontrolne i ogledne grupe svinja. Konverzija hrane bila je veća kod kontrolne grupe svinje.Na početku i na kraju tova mase kontrolnih i oglednih grupa svinja bile su ujednačene. Nisu utvrđene statistički značajne razlike između prosečne mase ohlađenih polutki, randmana, zbira debljine leđne slanine i procenta mesa u trupu oglednih i kontrolnih grupa svinja. Između pH vrednosti merene posle 60 minuta, odnosno merenih 24, 48 i 72 sata posle klanja nije utvrđena statistički značajna razlika. Nisu utvrđene statistički značajne razlike između prosečnih temperatura 60 minuta posle klanja, a takođe nisu utvrđene statistički značajne razlike između između prosečnih senzornih ocena boje, odnosno mramoriranosti mesa. Između prosečnih vrednosti sposobnosti vezivanja vode mesa ogledne i kontrolne grupe svinja nisu utvrđene statistički značajne razlike...

Advisors/Committee Members: Baltić, Milan Ž., 1948-.

Subjects/Keywords: pigs; conjugated linoleic acid; meat quality; fatty acid composition

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Pantić, Srđan M., 1. (2016). Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:10464/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Pantić, Srđan M., 1985-. “Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu.” 2016. Thesis, Univerzitet u Beogradu. Accessed March 07, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:10464/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Pantić, Srđan M., 1985-. “Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu.” 2016. Web. 07 Mar 2021.

Vancouver:

Pantić, Srđan M. 1. Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu. [Internet] [Thesis]. Univerzitet u Beogradu; 2016. [cited 2021 Mar 07]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:10464/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Pantić, Srđan M. 1. Uticaj konjugovane linolne kiseline na proizvodne rezultate, kvalitet mesa i proizvoda od mesa svinja u tovu. [Thesis]. Univerzitet u Beogradu; 2016. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:10464/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Univerzitet u Beogradu

4. Branković Lazić, Ivana M. Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera.

Degree: Fakultet veterinarske medicine, 2016, Univerzitet u Beogradu

URL: https://fedorabg.bg.ac.rs/fedora/get/o:10634/bdef:Content/get

►

Veterinarska medicina - Ishrana / Veterinary medicine - Nutrition

Osnovni cilj istraživanja u okviru ove doktorske disertacije je bio da se ispita uticaj konjugovane linolne… (more)

▼

Veterinarska medicina - Ishrana / Veterinary medicine - Nutrition

Osnovni cilj istraživanja u okviru ove doktorske disertacije je bio da se ispita uticaj konjugovane linolne kiseline (conjugated linoleic acid-CLA) na proizvodne rezultate (potrošnja hrane, prirast, konverzija), parametre mesnatosti (pocenat mesa u trupu) i kvalitet mesa brojlera (hemijski sastav, senzorne osobine, masnokiselinski sastav, uključujući sadržaj CLA, sadržaj malondialdehida). Za ogled su korišćeni brojleri Cobb 500 provenijencije podeljeni u četiri grupe po 30 životinja i hranjeni standardnim smešama po preporuci proizvođača, s tim što su se grupe razlikovale jedino u tome što su ogledne grupe imale u obroku dodat komercijalni preparat konjugovane kiseline, u preporučenoj količini od 2% u smeši u različitim fazama tova (O-I grupa 2% CLA od početka tova, O-II grupa 2% CLA od 11. dana tova, O-III grupa 2% CLA od 22. dana tova) i kontrolna grupa (K grupa) bez dodatka CLA. Smeše su bile izbalansirane i u potpunosti zadovoljavale potrebe životinja u svim fazama tova. Na kraju tova životinje su izmerene, izračunata je potrošena količina hrane, a na klanici uzeti uzorci masnog tkiva i mesa za hemijske analze (hemijski sastav mesa, MDA i masnokiselinski sastav) i senzorne analize. Uzorci mesa bataka sa karabatakom za određivanje sadržaja MDA zamrznuti su pri -18 °C. Na klanici su posle rasecanja izmerene mase osnovnih delova (grudi, batak sa karabatakom) trupa. Kod izoenergetskih i izoproteinskih smeša za ishranu brojlera utvrđene su statistički značajne razlike između prosečnih sadržaja zasićenih, mononezasićenih, polinezasićenih, n-3 i n-6 masnih kiselina. Utvrđena je statistički značajna razlika između odnosa n-3 i n-6 masnih kiselina. Prosečan ukupan sadržaj konjugovane linolne kiseline u smeši za ishranu oglednih grupa brojlera bio je 4,43 %. U hrani za kontrolnu grupu brojlera nije utvrđeno prisustvo konjugovane linolne kiseline. Na početku tova, a zatim na kraju prve i druge faze tova, kao i na kraju tova nisu utvrđene statistički značajne razlike između prosečnih masa ispitivanih grupa brojlera. Prosečan prirast za ceo period tova bio je najveći kod O-I grupe a najmanji kod K grupe brojlera, dok je ukupna konzumacija bila najveća kod K grupe a najmanja kod O-I grupe. Konverzija hrane bila je najbolja kod O-I grupe a najlošija kod kontrolne grupe brojlera. Prosečne mase trupova pre i posle hlađenja, zatim prosečne mase grudi i prosečne mase bataka sa karabatakom kao i njihova zastupljenost u masi trupa nisu se statistički značajno razlikovale između poređenih grupa brojlera. Takođe nije utvrđena statistički značajna razlika između prosečnih masa, odnosno učešća mesa u grudima, odnosno bataku sa karabatakom ispitivanih grupa brojlera. Između prosečnih pH vrednosti, odnosno prosečnih temperatura mesa merenih nakon 45 minuta, odnosno posle 24 sata od klanja nisu utvrđene statistički značajne razlike...

Advisors/Committee Members: Marković, Radmila, 1965-.

Subjects/Keywords: broilers; conjugated linoleic acid; production results; meat quality; fatty acid composition

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Branković Lazić, I. M. (2016). Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera. (Thesis). Univerzitet u Beogradu. Retrieved from https://fedorabg.bg.ac.rs/fedora/get/o:10634/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Branković Lazić, Ivana M. “Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera.” 2016. Thesis, Univerzitet u Beogradu. Accessed March 07, 2021. https://fedorabg.bg.ac.rs/fedora/get/o:10634/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Branković Lazić, Ivana M. “Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera.” 2016. Web. 07 Mar 2021.

Vancouver:

Branković Lazić IM. Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera. [Internet] [Thesis]. Univerzitet u Beogradu; 2016. [cited 2021 Mar 07]. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:10634/bdef:Content/get.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Branković Lazić IM. Uticaj primene konjugovane linolne kiseline na proizvodne rezultate i kvalitet mesa brojlera. [Thesis]. Univerzitet u Beogradu; 2016. Available from: https://fedorabg.bg.ac.rs/fedora/get/o:10634/bdef:Content/get

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Clemson University

5. Headley, Shannon. Effects of dietary supplementation of conjugated linoleic acid in horses.

Degree: MS, Animal and Veterinary Sciences, 2011, Clemson University

URL: https://tigerprints.clemson.edu/all_theses/1223

► Conjugated linoleic acid (CLA) reduces inflammation via the inhibition of cyclooxygenase II , thus reducing prostaglandin E2 (PGE2) production. Conjugated linoleic acid has a suggested… (more)

▼ Conjugated linoleic acid (CLA) reduces inflammation via the inhibition of cyclooxygenase II , thus reducing prostaglandin E2 (PGE2) production. Conjugated linoleic acid has a suggested osteoclast-suppressive role in bone remodeling and osteoarthritis, which are dependent on bone resorptive stimulator PGE2. Bone resorption marker, deoxypyridinoline (DPD), and bone formation marker, bone alkaline phosphatase (BAP), have been modulated by CLA supplementation in other species. Recent research in equine exercise physiology investigated dietary supplementation of polyunsaturated fatty acids as a possible prevention and treatment for osteoarthritis, but CLA supplementation has putative effects on skeletal function or inflammation in horses has not been reported. Our objective was to determine the effects of CLA supplementation on PGE2 in synovial fluid, BAP and DPD in serum, stride length and fetlock flexion and extension at the walk and trot, and body condition in healthy horses at maintenance. In a crossover study, 12 mares were blocked by breed, age, and body condition score (BCS) and separated into 2 treatment groups (n = 6/group). Groups were subjected to CLA and corn oil (CO) as an isocaloric control for 6 weeks (wk) separated by a 4-wk period during which treatment was withheld. Corn oil or CLA supplement (mixed isomers; source contained 55% CLA isomers) were incorporated into maintenance-level diets at 0.01% body weight (BW) per d over a six week period. Mares were fed individually and were restricted to dry lots to quantify forage intake. Synovial fluid, blood, rump fat thickness (RFT), BW and BCS were sampled before (d 0) and after (d42) of each feeding period. Walk and trot stride length and fetlock range of motion were assessed on d 0 and d 42 of feeding period 1 only. Immunoassay kits were used to quantify BAP and DPD in serum and PGE2 in synovial fluid. There were no observed differences in BW, RFT or BCS between the CLA and CO groups. While plasma CLA concentrations were higher in horses fed CLA compared to controls (P < 0.001), synovial fluid PGE2, serum BAP and serum DPD did not differ with treatment. Additionally, stride length and fetlock extension were not different at the walk or trot between treatments, nor was fetlock flexion at the walk. Despite absorption and incorporation of CLA into plasma, mares did not experience treatment effects on biochemical markers of joint inflammation, bone metabolism or kinematic performance. Examining the effects of CLA supplementation on horses at varying levels of growth, exercise, and progression of osteoarthritis may reveal more effects as to its potential benefits in the horse. Rate of dietary CLA incorporation, duration of supplementation, and isolated isomer studies may improve our understanding of these fatty acids in the equine diet. Advisors/Committee Members: Vernon, Kristine, Coverdale , Josie, Jenkins , Thomas, Sharp , Julia.

Subjects/Keywords: arachidonic acid; conjugated linoleic acid; horse; nutrition; prostaglandin E2; Animal Sciences

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Headley, S. (2011). Effects of dietary supplementation of conjugated linoleic acid in horses. (Masters Thesis). Clemson University. Retrieved from https://tigerprints.clemson.edu/all_theses/1223

Chicago Manual of Style (16^th Edition):

Headley, Shannon. “Effects of dietary supplementation of conjugated linoleic acid in horses.” 2011. Masters Thesis, Clemson University. Accessed March 07, 2021. https://tigerprints.clemson.edu/all_theses/1223.

MLA Handbook (7^th Edition):

Headley, Shannon. “Effects of dietary supplementation of conjugated linoleic acid in horses.” 2011. Web. 07 Mar 2021.

Vancouver:

Headley S. Effects of dietary supplementation of conjugated linoleic acid in horses. [Internet] [Masters thesis]. Clemson University; 2011. [cited 2021 Mar 07]. Available from: https://tigerprints.clemson.edu/all_theses/1223.

Council of Science Editors:

Headley S. Effects of dietary supplementation of conjugated linoleic acid in horses. [Masters Thesis]. Clemson University; 2011. Available from: https://tigerprints.clemson.edu/all_theses/1223

University of Georgia

6. Gillis, Margaret Hopson. Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/20565

► Lipid was supplied to feedlot cattle diets as either corn oil or rumen-protected conjugated linoleic acid (CLA) for two specific treatment periods of 32 d… (more)

Subjects/Keywords: Conjugated linoleic acid; Beef cattle; Leptin; Fatty acid composition

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gillis, M. H. (2014). Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/20565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gillis, Margaret Hopson. “Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots.” 2014. Thesis, University of Georgia. Accessed March 07, 2021. http://hdl.handle.net/10724/20565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gillis, Margaret Hopson. “Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots.” 2014. Web. 07 Mar 2021.

Vancouver:

Gillis MH. Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10724/20565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gillis MH. Effects of supplemental lipids on leptin levels and fatty acid composition of bovine adipose depots. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/20565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Georgia

7. Long, Jared Woodrow. Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle.

Degree: 2014, University of Georgia

URL: http://hdl.handle.net/10724/22958

► Lipid was supplied to feedlot cattle diets in the form of corn oil for 90 d in efforts to alter muscle fatty acid composition. Forty-one… (more)

Subjects/Keywords: Conjugated linoleic acid; Beef cattle; Anabolic implants; Fatty acid composition.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Long, J. W. (2014). Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/22958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Long, Jared Woodrow. “Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle.” 2014. Thesis, University of Georgia. Accessed March 07, 2021. http://hdl.handle.net/10724/22958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Long, Jared Woodrow. “Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle.” 2014. Web. 07 Mar 2021.

Vancouver:

Long JW. Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10724/22958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Long JW. Effects of supplemental lipid and anabolic growth implants on carcass characteristics, meat quality, and fatty acid composition of finishing beef cattle. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/22958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

8. Martinez, Sergio I. Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization.

Degree: PhD, Department of Agricultural, Food, and Nutritional Science, 2013, University of Alberta

URL: https://era.library.ualberta.ca/files/d504rm26z

► Conjugated linoleic acid (CLA), a bioactive lipid naturally found in milk, is thermally degraded through oxidation during thermal processing. Finding alternatives to enhance the retention… (more)

▼ Conjugated linoleic acid (CLA), a bioactive lipid naturally found in milk, is thermally degraded through oxidation during thermal processing. Finding alternatives to enhance the retention of CLA is challenging. In this thesis, high-pressure sterilization (HPS) was used to enhance CLA retention in milk. In addition, the effect of HPS on some quality indicators was evaluated, including lactulose formation, inactivation of alkaline phosphatase, and retention of CLA during storage. When HPS was applied (600 MPa and 120˚C), 78% of the CLA was retained after 15 min, while only 20% was retained after 15 min at 0.1 MPa and 120˚C. The retention kinetics was represented with Weibull model. To further improve the retention of CLA in milk, seven antioxidants, mainly phenolic acids, were evaluated. Gallic acid and catechin resulted in the highest retention of CLA after treatments at 600 MPa and 120˚C. Temperature and pressure accelerated the formation of lactulose, with a maximum value of 650 mg L-1 at 120˚C, 600 MPa and 15 min. The HPS conditions needed to reduce 7-log of Bacillus amyloliquefaciens endospores in inoculated milk were determined as well as the effect of adding nisin (4-64 mg L-1 milk). The inactivation kinetics of alkaline phosphatase was determined. Results showed that the addition of nisin (≥16 mg L-1) significantly enhanced the inactivation of Bacillus amyloliquefaciens (7-log reduction) after 5 min of treatment at 600 MPa and 120˚C, while without nisin 10 min were required to achieve the same log reduction. For storage, milk treated at 600 MPa and 120˚C for 5 min was selected to evaluate the impact of HPS on the CLA retention and formation of hydroperoxides. During storage, milk with nisin added and treated with HPS delivered higher CLA retention and lower hydroperoxides concentration compared with the UHT equivalent process. The kinetic information obtained was used to build pressure-temperature diagrams for CLA retention and lactulose formation. These data can be further used to design HPS processes, achieving high CLA retention.

Subjects/Keywords: High-pressure sterilization; Milk; Retention; Kinetics; Modeling; Conjugated linoleic acid

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Martinez, S. I. (2013). Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization. (Doctoral Dissertation). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/d504rm26z

Chicago Manual of Style (16^th Edition):

Martinez, Sergio I. “Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization.” 2013. Doctoral Dissertation, University of Alberta. Accessed March 07, 2021. https://era.library.ualberta.ca/files/d504rm26z.

MLA Handbook (7^th Edition):

Martinez, Sergio I. “Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization.” 2013. Web. 07 Mar 2021.

Vancouver:

Martinez SI. Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization. [Internet] [Doctoral dissertation]. University of Alberta; 2013. [cited 2021 Mar 07]. Available from: https://era.library.ualberta.ca/files/d504rm26z.

Council of Science Editors:

Martinez SI. Kinetics studies of chemical reactions and quality changes in conjugated linoleic acid (CLA) enriched milk treated with high-pressure sterilization. [Doctoral Dissertation]. University of Alberta; 2013. Available from: https://era.library.ualberta.ca/files/d504rm26z

University of Louisville

9. Van Hoose, Patrick. Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury.

Degree: PhD, 2015, University of Louisville

URL: 10.18297/etd/2293 ; https://ir.library.louisville.edu/etd/2293

► Cardiovascular disease and subsequent complications, such as myocardial infarction (MI), is the leading cause of death within the United States. Clinical intervention to reduce… (more)

▼ Cardiovascular disease and subsequent complications, such as myocardial infarction (MI), is the leading cause of death within the United States. Clinical intervention to reduce cardiac damage following myocardial ischemia is limited. Polyunsaturated fatty acids have been linked to an overall beneficial effect on cardiovascular health and function. Conjugated linoleic acid (cLA) is an 18:2 unsaturated fatty acid found within the diet in ruminant meat and dairy products. The cis-9 trans-11 isomer of cLA is the most prominent isomer within the diet and cLA has been linked to favorable outcomes in numerous disease states. The mechanism mediating the effects of cLA are still unclear but mitochondria appear to be playing a prominent role. Nitrite (NO₂^-) is a dietary source of nitric oxide (NO), as it is found within green leafy vegetables and it is linked to cardioprotection in ischemia reperfusion injury models. Alterations in mitochondrial function and electron transport chain enzymatic activity have been elucidated as the mechanisms mediating nitrite cardioprotection. However, recent clinical trials have reported no positive outcome in patients undergoing MI who have been supplemented with nitrite. A combination treatment of cLA and nitrite preserves cardiac function following MI, highlighting that the interaction between dietary constituents may influence cardioprotective effects. In the first step of this study, we examine whether the combination treatment of cLA and nitrite influenced mitochondrial respiration and electron transport chain activity under baseline conditions. In the second step of this study, we examine the impact of co-treatment with cLA and nitrite on mitochondrial function following MI and aging. Under baseline conditions, we found that co-administration of cLA and nitrite decreased mitochondrial respiration and complex III activity. Following MI, the co-treatment of cLA and nitrite attenuated MI-induced increases in mitochondrial respiration, complex III activity, and hydrogen peroxide levels. However, following aging the co-treatment was unable to restore aging induced mitochondrial dysfunction. These results demonstrate that in combination the dietary constituents, cLA and nitrite, are able to influence mitochondrial function under non-injury setting and following MI. Overall, this supports a role of mitochondria in the cardioprotective effects mediated by a combination treatment of cLA and nitrite. Advisors/Committee Members: Cole, Marsha, Hill, Brad, Hill, Brad, Clark, Barbara, Cheng, Alan, Schaner-Tooley, Christine.

Subjects/Keywords: mitochondria; conjugated linoleic acid; nitrite; myocardial injury; Biochemistry; Molecular Biology

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Van Hoose, P. (2015). Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. (Doctoral Dissertation). University of Louisville. Retrieved from 10.18297/etd/2293 ; https://ir.library.louisville.edu/etd/2293

Chicago Manual of Style (16^th Edition):

Van Hoose, Patrick. “Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury.” 2015. Doctoral Dissertation, University of Louisville. Accessed March 07, 2021. 10.18297/etd/2293 ; https://ir.library.louisville.edu/etd/2293.

MLA Handbook (7^th Edition):

Van Hoose, Patrick. “Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury.” 2015. Web. 07 Mar 2021.

Vancouver:

Van Hoose P. Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. [Internet] [Doctoral dissertation]. University of Louisville; 2015. [cited 2021 Mar 07]. Available from: 10.18297/etd/2293 ; https://ir.library.louisville.edu/etd/2293.

Council of Science Editors:

Van Hoose P. Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. [Doctoral Dissertation]. University of Louisville; 2015. Available from: 10.18297/etd/2293 ; https://ir.library.louisville.edu/etd/2293

Texas A&M University

10. Nall, Jennifer L. Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats.

Degree: MS, Nutrition, 2010, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2008-05-16

► We hypothesized that subcutaneous (s.c.) adipose tissue would differ in monounsaturated (MUFA) and saturated fatty acid (SFA) composition among different depots throughout a beef carcass.… (more)

Subjects/Keywords: arginine; conjugated linoleic acid

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Nall, J. L. (2010). Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats. (Masters Thesis). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2008-05-16

Chicago Manual of Style (16^th Edition):

Nall, Jennifer L. “Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats.” 2010. Masters Thesis, Texas A&M University. Accessed March 07, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2008-05-16.

MLA Handbook (7^th Edition):

Nall, Jennifer L. “Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats.” 2010. Web. 07 Mar 2021.

Vancouver:

Nall JL. Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats. [Internet] [Masters thesis]. Texas A&M University; 2010. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2008-05-16.

Council of Science Editors:

Nall JL. Arginine and Conjugated Linoleic Acid Reduce Fat Mass in Rats. [Masters Thesis]. Texas A&M University; 2010. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2008-05-16

11. Peters, Leah. The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice.

Degree: Human Nutritional Sciences, 2011, University of Manitoba

URL: http://hdl.handle.net/1993/4793

► Fertility in human males is negatively correlated with obesity and diabetes mellitus (DM). Whether CLA influences obesity and DM associated infertility has not been studied.… (more)

Subjects/Keywords: Conjugated Linoleic Acid; Spermatogenesis

…Seminolipid synthesis �� ........... …11 Figure I-4A Linoleic acid and conjugated… …CLA conjugated linoleic acid CPT carnitine palmitoyl transferase cst cerebroside-3… …Acid (CLA) 5.1. Structure, Metabolism and Absorption Conjugated linoleic acid… …Figure I-4A: Linoleic acid and conjugated linoleic acid isomers, cis-9, trans-11 and trans-10… …linoleic acid isomers, cis-9, trans-11 and trans-10, cis-12 �� ….. …25 Figure I-4B…

8 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Peters, L. (2011). The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/4793

Chicago Manual of Style (16^th Edition):

Peters, Leah. “The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice.” 2011. Masters Thesis, University of Manitoba. Accessed March 07, 2021. http://hdl.handle.net/1993/4793.

MLA Handbook (7^th Edition):

Peters, Leah. “The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice.” 2011. Web. 07 Mar 2021.

Vancouver:

Peters L. The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice. [Internet] [Masters thesis]. University of Manitoba; 2011. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1993/4793.

Council of Science Editors:

Peters L. The effects of conjugated linoleic acid on spermatogenesis in DB/DB mice. [Masters Thesis]. University of Manitoba; 2011. Available from: http://hdl.handle.net/1993/4793

University of Manitoba

12. Yeganeh, Azadeh. Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice.

Degree: Physiology and Pathophysiology, 2015, University of Manitoba

URL: http://hdl.handle.net/1993/31099

► The high rate of obesity is having a significant impact on human health. Understanding the underlying biological mechanisms that regulate adipogenesis and adipocyte lipid metabolism… (more)

▼ The high rate of obesity is having a significant impact on human health. Understanding the underlying biological mechanisms that regulate adipogenesis and adipocyte lipid metabolism is necessary to identify novel approaches that promote weight loss. Conjugated linoleic acid (CLA) is an example of a naturally-derived product reported to exhibit an anti-obesity effect. For this thesis, it was hypothesized that the anti-obesity effects of the t10-c12 CLA isomer is due to lipid droplet dynamics alteration through activation of the Wnt/β-catenin pathway, which leads to weight loss via affecting adipogenesis and/or adipocyte death. Testing of this hypothesis was achieved by examining the effects of the most biologically active CLA isomers, cis-9, trans-11 (c9-t11), trans-10, cis-12 (t10-c12) CLA using in vitro (3T3-L1 cell line) and in vivo (mouse) models. In 3T3-L1 preadipocytes, both c9-t11 and t10-c12 CLA stimulated early stage differentiation, while t10-c12 CLA inhibited late differentiation as indicated by fewer lipid droplets, lower adipokine levels, and decreased levels of perilipin-1 and phospho-perilipin-1 compared to null. The t10-c12 CLA isomer decreased hormone-sensitive lipase (HSL) levels and inhibited lipolysis by activating protein kinase Cα (PKCα). As well, t10-c12-CLA inhibited adipocyte differentiation by stabilizing β-catenin, which sequesters peroxisome proliferator-activated receptor-γ in an inactive complex. Reduced body weight in both db/db and C57B/L6 mice fed t10-c12 CLA was due to less white and brown fat mass without changes in lean body mass or an alteration in feed intake compared to their respective control. t10-c12 CLA did not stimulate cell death in white adipose tissue. Immune cell infiltration was decreased in calorie restricted pair weight control mice, but not with CLA. t10-c12 CLA-induced weight loss did not improve hyperglycemia in db/db mice. In conclusion, the anti-adipogenic effects of t10-c12 CLA in vitro result from stabilization of β-catenin, which alters lipid droplet dynamics through HSL levels and perilipin-1 phosphorylation via the activation of PKCα. In contrast, t10-c12 CLA promotes loss of adipose tissue in vivo, possibly by activating β-catenin, but without influencing either adipogenesis or adipocyte clearance. This study suggests a novel mechanism for the anti-obesity effect of t10-c12 CLA, and highlights the possible side-effects associated with t10-c12 CLA consumption. Advisors/Committee Members: Zahradka, Peter (Physiology and Pathophysiology) Taylor, Carla (Human Nutritional Sciences) (supervisor), Cattini, Peter (Physiology and Pathophysiology) Kardami, Elissavet ( Human anatomy and Cell Science) Wigle, Jeffrey (Biochemistry and Medical Genetics) Tchernof, Andre (Endocrinology and nephrology, Universite Laval) (examiningcommittee).

Subjects/Keywords: Obesity; Adipocytes; Conjugated linoleic acid; Beta-catenin; Perilipin

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Yeganeh, A. (2015). Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/31099

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Yeganeh, Azadeh. “Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice.” 2015. Thesis, University of Manitoba. Accessed March 07, 2021. http://hdl.handle.net/1993/31099.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Yeganeh, Azadeh. “Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice.” 2015. Web. 07 Mar 2021.

Vancouver:

Yeganeh A. Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice. [Internet] [Thesis]. University of Manitoba; 2015. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1993/31099.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Yeganeh A. Investigating the mechanisms involved in the anti-obesity effect of conjugated linoleic acid (CLA) isomers in 3T3-L1 adipocytes, and in obese db/db and lean C57BL/6 mice. [Thesis]. University of Manitoba; 2015. Available from: http://hdl.handle.net/1993/31099

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manitoba

13. Liu, Xiaoran. Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model.

Degree: Food Science, 2010, University of Manitoba

URL: http://hdl.handle.net/1993/4112

► The objectives of this study was to examine the efficacy and safety of graded doses of c9, t11, t10, c12 CLA isomers on body composition,… (more)

Subjects/Keywords: Conjugated linoleic acid; hamster; body composition; lipid profile; liver biomarker

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Liu, X. (2010). Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model. (Masters Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/4112

Chicago Manual of Style (16^th Edition):

Liu, Xiaoran. “Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model.” 2010. Masters Thesis, University of Manitoba. Accessed March 07, 2021. http://hdl.handle.net/1993/4112.

MLA Handbook (7^th Edition):

Liu, Xiaoran. “Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model.” 2010. Web. 07 Mar 2021.

Vancouver:

Liu X. Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model. [Internet] [Masters thesis]. University of Manitoba; 2010. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1993/4112.

Council of Science Editors:

Liu X. Dosage ranging effect and safety evaluation of conjugated linoleic acid (CLA) in a hamster model. [Masters Thesis]. University of Manitoba; 2010. Available from: http://hdl.handle.net/1993/4112

University of the Western Cape

14. Arendse, Lyle. The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro .

Degree: 2014, University of the Western Cape

URL: http://hdl.handle.net/11394/4665

► Conjugated linoleic acids (CLA) are geometrical and positional isomers of n-6 octadecadenoic acid (linoleic acid, LA, 18:2n-6), which form part of a family of essential… (more)

Subjects/Keywords: Conjugated linoleic acid; Cancer; Lipid peroxidation; Cell cycle

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Arendse, L. (2014). The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/4665

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Arendse, Lyle. “The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro .” 2014. Thesis, University of the Western Cape. Accessed March 07, 2021. http://hdl.handle.net/11394/4665.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Arendse, Lyle. “The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro .” 2014. Web. 07 Mar 2021.

Vancouver:

Arendse L. The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro . [Internet] [Thesis]. University of the Western Cape; 2014. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/11394/4665.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Arendse L. The modulating effect of conjugated linoleic acid (CLA) on cancer cell survival in vitro . [Thesis]. University of the Western Cape; 2014. Available from: http://hdl.handle.net/11394/4665

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Illinois – Urbana-Champaign

15. Weitekamp, Catherine. Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem.

Degree: MS, 0002, 2014, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/50556

► The effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on Longissiumus… (more)

▼ The effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on Longissiumus muscle quality, belly characteristics, and fat quality measured post mortem was evaluated in a study carried out on a commercial wean-to-finish facility. A randomized complete block design with 15 treatments consisting of different combinations of Dietary Program (i.e., 0% DDGS, 30% DDGS, and DDGS withdrawal [30% DDGS from week 0 to approximately 104 kg and 0% DDGS from approximately 104 kg to end of study]), CLA Inclusion Level (i.e., 0, 0.5, and 1.0%), and CLA Feeding Duration (i.e., 0, 14, and 28 days prior to harvest). The treatments (Trt.) were defined by the combination of Dietary Program, CLA Inclusion level, and CLA Feeding Duration and were as follows: Trt. 1 (0%, 0%, and 0 days), Trt. 2 (30%, 0%, and 0 days), Trt. 3 (Withdrawal, 0%, and 0 days), Trt. 4 (0%, 0.5%, 14 days), Trt. 5 (30%, 0.5%, 14 days), Trt. 6 (Withdrawal, 0.5%, 14 days), Trt. 7 (0%, 0.5%, 28 days), Trt. 8 (30%, 0.5%, 28 days), Trt. 9 (Withdrawal, 0.5%, 28 days), Trt. 10 (0%, 1.0%, 14 days), Trt. 11 (30%, 1.0%, 14 days), Trt. 12 (Withdrawal, 1.0%, 14 days), Trt. 13 (0%, 1.0%, 28 days), Trt. 14 (30%, 1.0%, 28 days), Trt. 15 (Withdrawal, 1.0%, 28 days). Pen was the experimental unit. The study used a total of 3,300 pigs housed in pens of 20 with 11 pens per treatment. This study was carried out from an initial live weight of 92.2 ± 1.20 kg for a fixed-time feeding period of 70 days (to Week 10 of the study), with CLA being fed for the last 14 or 28 days prior to harvest according to treatment. All pigs were individually weighed at the start of the study. Group pen weights were collected on all replicates at the start of study, week 3, 6, 8, and 10 of the study period. At the end of Week 10 of study, all pens in a replicate were taken off test, and sent for harvest on the same day. Carcass, Longissiumus muscle, belly, and fat quality measures were collected after harvest. At approximately 24 h post mortem, a fat sample was taken and near-infrared spectroscopy (NIR) was performed on the sample, to measure iodine value. Including 30% DDGS in the diet reduced (P < 0.05) growth performance (i.e., ADG and G:F), carcass characteristics (i.e., carcass yield and 10th rib backfat depth), belly firmness (i.e., belly flop distance and subjective firmness score), and increased (P < 0.05) iodine value by on average 7.46 g/100g (68.88 to 76.34 g/100g), when compared to pigs fed 0% DDGS. Withdrawing DDGS from the diet for the last 4 wk before harvest increased (P < 0.05) growth performance, carcass yield, belly firmness (i.e., belly flop distance and subjective firmness score), and reduced (P < 0.05) iodine value by on average 3.61 units (76.34 to 72.73 g/100g), when compared to pigs fed 30% DDGS. The level and duration of feeding CLA had no effect (P > 0.05) on growth performance; however, feeding diets with 1% CLA for 28 days increased (P < 0.05) flop distance and subjective… Advisors/Committee Members: Ellis, Michael (advisor).

Subjects/Keywords: Pigs; Conjugated Linoleic Acid; Corn Distiller Dried Grain with Solubles

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Weitekamp, C. (2014). Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/50556

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Weitekamp, Catherine. “Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem.” 2014. Thesis, University of Illinois – Urbana-Champaign. Accessed March 07, 2021. http://hdl.handle.net/2142/50556.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Weitekamp, Catherine. “Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem.” 2014. Web. 07 Mar 2021.

Vancouver:

Weitekamp C. Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2014. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2142/50556.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Weitekamp C. Effect of level and duration of feeding conjugated linoleic acid in different dietary programs on the growth performance of growing-finishing pigs and on longissiumus muscle quality, belly characteristics, and fat quality measured post mortem. [Thesis]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/50556

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

16. Miller, Elizabeth F. The effect of CLA supplementation on fat deposition and lean muscle mass in horses.

Degree: 2017, Sam Houston State University

URL: http://hdl.handle.net/20.500.11875/2178

► Fatty acids are utilized within the equine industry to increase the caloric density of a diet as well as replace soluble carbohydrates. Omega-3 fatty acids… (more)

▼ Fatty acids are utilized within the equine industry to increase the caloric density of a diet as well as replace soluble carbohydrates. Omega-3 fatty acids are the most commonly supplemented fatty acids due to their potential health benefits; however, palatability limitations have spurred an investigation into alternative fatty acids like conjugated linoleic acid (CLA). CLA has shown health benefits similar to that of omega-3s, but the effect of CLA on equine fat deposition and lean muscle mass has yet to be established. The purpose of this investigation was to evaluate the effects of supplementing elevated levels of CLA on both lean muscle mass and fat deposition in young growing horses. In phase I of this study, 10 Quarter horses were fed between 5.0% and 10.0% of the concentrate diet, increasing the supplementation level every 3 d to determine the maximum inclusion rate of CLA in horses. In phase II, 9 Quarter horses were separated into 2 treatment groups fed either a control diet of soybean oil or CLA (n = 4 and 5/group, respectively) for 12-wks with BW and sex evenly distributed across treatments. Diets were formulated to be isocaloric and isonitrogenous and each treatment was offered at 0.015% BW/d. Growth measurements were collected weekly; rump fat thickness (RFT), ribeye area (REA), back fat (BF) and intramuscular fat (IMF) were measured on d 7, d 42, and d 84 of the feeding period. The MIXED procedure in SAS was used with repeated measures to detect differences in growth performance and ultrasound measurements. There were no differences in performance characteristics or fat content between treatment groups (P > 0.05). In order to account for initial differences between treatments (P < 0.05); REA between the 17th and 18th ribs (REA17) was run with d 7 as a covariate. Mean REA17 tended to be higher in CLA supplemented horses (P < 0.07) when compared to controls. These results suggest that in an equine model, CLA does not affect growth performance or fat deposition, but may increase lean muscle mass in young growing horses. Further studies examining these effects over longer supplementation periods or in obese or insulin-resistant horses may offer insight to potential benefits of CLA in the horse. Advisors/Committee Members: Beverly, Marcy M. (advisor), Leatherwood, Jessica L. (committee member), Anderson, Mark J. (committee member).

Subjects/Keywords: Conjugated linoleic acid; CLA; Horses; Fat deposition; Lean muscle mass

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Miller, E. F. (2017). The effect of CLA supplementation on fat deposition and lean muscle mass in horses. (Thesis). Sam Houston State University. Retrieved from http://hdl.handle.net/20.500.11875/2178

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Miller, Elizabeth F. “The effect of CLA supplementation on fat deposition and lean muscle mass in horses.” 2017. Thesis, Sam Houston State University. Accessed March 07, 2021. http://hdl.handle.net/20.500.11875/2178.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Miller, Elizabeth F. “The effect of CLA supplementation on fat deposition and lean muscle mass in horses.” 2017. Web. 07 Mar 2021.

Vancouver:

Miller EF. The effect of CLA supplementation on fat deposition and lean muscle mass in horses. [Internet] [Thesis]. Sam Houston State University; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/20.500.11875/2178.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Miller EF. The effect of CLA supplementation on fat deposition and lean muscle mass in horses. [Thesis]. Sam Houston State University; 2017. Available from: http://hdl.handle.net/20.500.11875/2178

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Brno University of Technology

17. Ruprichová, Lenka. Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA).

Degree: 2019, Brno University of Technology

URL: http://hdl.handle.net/11012/11795

► This work deals with the optimization of the method for determination of conjugated linoleic acid (CLA) using gas chromatography. The summary about formation and occurrence… (more)

Subjects/Keywords: Konjugovaná linolová kyselina; plynová chromatografie.; Conjugated linoleic acid; gas chromatography.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ruprichová, L. (2019). Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA). (Thesis). Brno University of Technology. Retrieved from http://hdl.handle.net/11012/11795

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ruprichová, Lenka. “Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA).” 2019. Thesis, Brno University of Technology. Accessed March 07, 2021. http://hdl.handle.net/11012/11795.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ruprichová, Lenka. “Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA).” 2019. Web. 07 Mar 2021.

Vancouver:

Ruprichová L. Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA). [Internet] [Thesis]. Brno University of Technology; 2019. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/11012/11795.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ruprichová L. Zavedení metody stanovení konjugované linolové kyseliny (CLA): Introduction of the method for assessment of conjugated linoleic acid (CLA). [Thesis]. Brno University of Technology; 2019. Available from: http://hdl.handle.net/11012/11795

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Santo, Ana Paula do Espirito. Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total.

Degree: PhD, Tecnologia de Alimentos, 2012, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/9/9133/tde-21032013-143954/ ;

►

Novas tendências para desenvolvimento de leites fermentados com elevado valor agregados são o uso de frutos da Amazônia e a utilização de subprodutos de certas… (more)

▼

Novas tendências para desenvolvimento de leites fermentados com elevado valor agregados são o uso de frutos da Amazônia e a utilização de subprodutos de certas frutas como forma de aproveitamento integral do fruto e para minimizar a produção de resíduos. Dentre os frutos da Amazônia o açaí (Euterpe oleracea Mart., Arecaceae) tem o maior potencial enquanto alguns subprodutos de frutos como as cascas de maçã, banana e maracujá são promissores como ingredientes especialmente devido ao seu conteúdo em fibras dietéticas solúveis prebióticas como pectina e frutooligossacarídeos, que conferem propriedades funcionais além das características nutricionais das frutas. Assim, esse trabalho visou o desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total. Os efeitos da suplementação do leite com polpa de açaí e fibras de maçã, banana e maracujá e, diferentes bactérias probióticas - Lactobacillus acidophilus L10, Bifidobacterium animalis ssp. lactis Bl04 e B94 e Bifidobacterium longum Bl05 na cinética de acidificação, viabilidade dos probióticos, perfil de ácidos graxos, textura, reologia e microestrutura foram estudados. A polpa de açaí favoreceu uma maior contagem de L. acidophilus L10, B. animalis ssp. lactis Bl04 e B. longum Bl05 em relação aos respectivos controles ao final de quatro semanas de vida de prateleira. Além disso, em relação aos controles sem polpa, a polpa de açaí aumentou o conteúdo de ácidos graxos mono e poliinsaturados e a produção de ácido α-linolênico (ALA) e ácido linoléico conjugado (CLA) em iogurtes desnatados co-fermentados com B. animalis ssp. lactis cepas Bl04 e B94. Todas as fibras foram capazes de aumentar a concentração de ácidos graxos de cadeia curta e poliinsaturados nos iogurtes, mas, apenas as fibras de maçã e banana aumentaram a viabilidade das bactérias probióticas durante a vida de prateleira em relação aos controles sem fibra. Foi observado um efeito sinérgico entre o tipo de fibra e a cepa probiótica sobre o teor de CLA. Por outro lado, a quantidade de ALA foi significativamente aumentada pela adição de fibra de banana, independentemente da cepa probiótica utilizada. A fibra de maracujá promoveu o aumento CLA em todos os iogurtes probióticos. Os resultados demonstram, pela primeira vez, que tanto a polpa de açaí quanto as fibras oriundas do subproduto do processamento de maçã, banana ou maracujá podem melhorar o perfil de ácidos graxos e a viabilidade de bactérias probióticas. Além disso, a fibra de casca de maracujá teve um efeito positivo sobre a textura de iogurtes desnatados co-fermentados por bifidobacteria.

New trends for development of fermented milk products with high added value are the use of fruits from Amazon, and the use of by-products of certain fruits as ingredients as a way to take full advantage of the fruit and to minimize the waste. Among the fruits of the Amazon, açai (Euterpe oleracea Mart., Arecaceae) has the most potential, and byproducts of some fruits such as apple peels, banana and passion fruit as…

Advisors/Committee Members: Oliveira, Marice Nogueira de.

Subjects/Keywords: Ácido linoléico conjugado; Conjugated linoleic acid; Iogurte; Probiotic; Probiótico; Textura; Texture; Viabilidade; Viability; Yoghurt

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Santo, A. P. d. E. (2012). Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/9/9133/tde-21032013-143954/ ;

Chicago Manual of Style (16^th Edition):

Santo, Ana Paula do Espirito. “Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total.” 2012. Doctoral Dissertation, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/9/9133/tde-21032013-143954/ ;.

MLA Handbook (7^th Edition):

Santo, Ana Paula do Espirito. “Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total.” 2012. Web. 07 Mar 2021.

Vancouver:

Santo APdE. Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total. [Internet] [Doctoral dissertation]. University of São Paulo; 2012. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/9/9133/tde-21032013-143954/ ;.

Council of Science Editors:

Santo APdE. Desenvolvimento de iogurte probiótico com adição de polpa de frutos brasileiros e fibra dietética total. [Doctoral Dissertation]. University of São Paulo; 2012. Available from: http://www.teses.usp.br/teses/disponiveis/9/9133/tde-21032013-143954/ ;

Texas A&M University

19. Shin, Dae Keun. Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat.

Degree: PhD, Poultry Science, 2011, Texas A&M University

URL: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7698

► Two different studies were conducted to reduce the overall amount of omega-6 fatty acids in broiler chickens. The first experiment was performed to determine the… (more)

▼ Two different studies were conducted to reduce the overall amount of omega-6 fatty acids in broiler chickens. The first experiment was performed to determine the effects of dietary conjugated linoleic acid (CLA) and omega-3 fatty acid combination on the omega-6 fatty acid accumulation in broiler chicken breast and thigh meat. Eight broilers from each treatment were processed at 4 and 6 weeks of age, respectively. Regarding the diets containing five different fat sources, broiler chickens fed CLA and fish oil diet had a lower C20:4 (arachidonic acid, AA, n-6) deposition but showed a higher n-3/n-6 ratio in breast and thigh meat than those fed a flaxseed oil diet and CLA and flaxseed oil diet (P < 0.05). The C20:4 and n-3/n-6 ratio of breast and thigh samples from fish oil diet was similar to those of the conjugated linoleic acid and fish oil combination diet (P > 0.05). However, the addition of CLA and fish oil to the diet resulted in a increase of polyunsaturated fatty acid (PUFA) concentration in broiler chicken breast and thigh meat when compared to that of fish oil diet (P<0.05). The second experiment was conducted based on six different combination of n-3 and n-9 fatty acids. One bird per pen was processed, and each bird was weighed, and blood, liver, breast and thigh samples from the bird were collected. Although the generation of prostaglandin E2 (PGE2) was not affected due to combination of n-3 and n-9 fatty acids in our diets, the deposition of n-6 fatty acids including C18:2 and C20:4 was decreased in broiler chicken breast and/or thigh muscles as n-3 fatty acids were supplied to broiler chickens for 9 weeks. Eicosapentaenoic acid (C20:5, EPA, n-3) addition to poultry diet (FEO) did not reduce the deposition of C18:2 and/or C20:4 as much as C22:6 (FDO) did. When C20:5 and C22:6 were blended to poultry diet (FHO) and fed to broiler chickens for 9 weeks, synergistic effects were observed. Reduction of C20:4 was obtained when FHO diet was fed to broiler chickens, and it may be induced due to decreased expression of delta-6 desaturase mRNA. Advisors/Committee Members: Sanchez-Plata, Marcos X. (advisor), Ruiz-Feria, Ciro A. (advisor), Smith, Stephen B. (committee member), Morgan, Caurnel A. (committee member), Cisneros-Zevallos, Luis (committee member).

Subjects/Keywords: Omega-3; omega-6; fatty acids; conjugated linoleic acid; omega-9; inflammation

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shin, D. K. (2011). Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7698

Chicago Manual of Style (16^th Edition):

Shin, Dae Keun. “Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat.” 2011. Doctoral Dissertation, Texas A&M University. Accessed March 07, 2021. http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7698.

MLA Handbook (7^th Edition):

Shin, Dae Keun. “Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat.” 2011. Web. 07 Mar 2021.

Vancouver:

Shin DK. Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat. [Internet] [Doctoral dissertation]. Texas A&M University; 2011. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7698.

Council of Science Editors:

Shin DK. Effect of Conjugated Linoleic Acid or Oleic Acid Addition on Fatty Acid Composition Profiles of Poultry Meat. [Doctoral Dissertation]. Texas A&M University; 2011. Available from: http://hdl.handle.net/1969.1/ETD-TAMU-2010-05-7698

Texas A&M University

20. Hossen, Md Monjur. Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols.

Degree: PhD, Food Science and Technology, 2006, Texas A&M University

URL: http://hdl.handle.net/1969.1/3748

► Structured phospholipids with functional ingredients like conjugated linoleic acid (CLA) and plant sterols to deliver their physiological effects in different food formulations were synthesized. The… (more)

▼ Structured phospholipids with functional ingredients like conjugated linoleic acid (CLA) and plant sterols to deliver their physiological effects in different food formulations were synthesized. The lipase and phospholipase A2 catalyzed enzymatic acidolysis reaction between phospholipids (PLs) and CLA was used for fatty acid modification, while the phospholipase D catalyzed transphosphatidylation reaction between PLs and sterol was used for head group modification. Enzymatic processes were an effective way to produce structured phospholipids. Screening of four lipases and immobilized phospholipase A2 and combination of lipase and phospholipase showed that only Lipozyme RM IM and Lipozyme TL IM were effective in incorporation of CLA into PLs. The maximum incorporation achieved by the latter enzyme was 16% with soy PLs in 72 h. The class of phospholipids had a significant effect on the rate of incorporation of CLA compare to source of PLs. A method capable of predicting the rate of incorporation of CLA into phospholipids was developed using response surface methodology. A three-level four-factor Central Composite Rotatable Design (CCRD) was used. The four factors selected were lipase dosage (Ed, wt.% of substrate), substrate ratio (Sr,mol%), reaction time (ti, h) and reaction temperature (Te,oC). The enzyme load and substrate ratio had a greater effect on the rate of incorporation than did reaction time and temperature. A polynomial regression equation was developed to predict the reaction rate. The new phosphatidyl derivative, phosphatidyl-sitosterol, was found to be synthesized by the transfer reaction of phosphatidyl residue from phosphatidylcholine to β-sitosterol by phospholipase D from Streptomyces sp. in biphasic medium. The novel phosphatidyl .sitosterol derivative was identified by MALDI-TOF mass spectrometry. Plant sterols were modified to a more polar lipid class by synthesizing phospholipid derivatives of them. When these structured phospholipids were added to a whey protein based oil-in-water emulsion, the CLA incorporated structured phospholipids (CLA-PL) had higher heat stability and oxidative stability compared to the controls. Advisors/Committee Members: , (advisor), Hernandez, Ernesto (advisor), Rooney, Lloyd (advisor), Richter, Ronald (committee member), Walzem, Rosemary (committee member).

Subjects/Keywords: Phospholipids; Conjugated linoleic acid; plant sterol

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hossen, M. M. (2006). Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols. (Doctoral Dissertation). Texas A&M University. Retrieved from http://hdl.handle.net/1969.1/3748

Chicago Manual of Style (16^th Edition):

Hossen, Md Monjur. “Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols.” 2006. Doctoral Dissertation, Texas A&M University. Accessed March 07, 2021. http://hdl.handle.net/1969.1/3748.

MLA Handbook (7^th Edition):

Hossen, Md Monjur. “Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols.” 2006. Web. 07 Mar 2021.

Vancouver:

Hossen MM. Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols. [Internet] [Doctoral dissertation]. Texas A&M University; 2006. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1969.1/3748.

Council of Science Editors:

Hossen MM. Enzyme catalyzed synthesis of structured phospholipids with conjugated linoleic acid and plant sterols. [Doctoral Dissertation]. Texas A&M University; 2006. Available from: http://hdl.handle.net/1969.1/3748

21. Li, Jing. Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice.

Degree: MS, 0191, 2011, University of Illinois – Urbana-Champaign

URL: http://hdl.handle.net/2142/24310

► Trans-10, cis-12-conjugated linoleic acid (trans-10, cis-12-CLA) has been reported to reduce body fat mass but accompanied by increased liver mass. However, the cellular and molecular… (more)

Subjects/Keywords: Conjugated linoleic acid; hepatic steatosis

…effect of 6 weeks of supplementation of 0.5% linoleic acid, cis-9, trans-11-CLA or trans-10… …that in the linoleic acid group; and, that reduced fat deposition in liver was not apparently… …x29; and lipid disposal (via fatty acid oxidation or TG-rich lipoprotein secretion)… …fatty acid oxidation, lipolysis, differentiation and lipogenesis (6, 32). A study… …trans-10, cis-12-CLA-induced hyperinsulinemia, by inducing both fatty acid uptake and…

5 more images…

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Li, J. (2011). Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/24310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Li, Jing. “Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice.” 2011. Thesis, University of Illinois – Urbana-Champaign. Accessed March 07, 2021. http://hdl.handle.net/2142/24310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Li, Jing. “Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice.” 2011. Web. 07 Mar 2021.

Vancouver:

Li J. Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2011. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/2142/24310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Li J. Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice. [Thesis]. University of Illinois – Urbana-Champaign; 2011. Available from: http://hdl.handle.net/2142/24310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Maryland

22. Vyas, Diwakar. Denovo synthesized fatty acids as regulators of milk fat synthesis.

Degree: Animal Sciences, 2011, University of Maryland

URL: http://hdl.handle.net/1903/12306

► The objectives of the dissertation research were to determine the role of denovo synthesized fatty acids (DNFA) in the regulation of milk fat synthesis. Milk… (more)

▼ The objectives of the dissertation research were to determine the role of denovo synthesized fatty acids (DNFA) in the regulation of milk fat synthesis. Milk fat responses to increasing amounts of short- and medium-chain fatty acids (SMCFA), added in the proportion as synthesized denovo, were studied in lactating dairy cows. The results showed a significant linear increase in milk fat concentration with SMCFA supplementation. However, milk fat yield was similar for all treatments. A subsequent study was aimed at increasing the availability of SMCFA during trans-10, cis-12 CLA-induced milk fat depression (MFD) in lactating dairy cows to determine whether SMCFA can rescue part of CLA-induced MFD. Post-ruminal infusion of butterfat (BF) was used as a source of SMCFA. The BF treatment was compared to a mixture of fats containing only the long-chain FA (LCFA) with or without trans-10, cis-12 CLA infusion. Milk fat content and yield were significantly reduced with trans-10, cis-12 CLA. However, increased availability of SMCFA with BF infusion had no effects on milk fat yield and concentration. Trans-10, cis-12 CLA significantly reduced the mRNA expression of transcription factor SREBP-1c along with its downstream targets including ACC,FASN, LPL, SCD and AGPAT. The increased availability of SMCFA had no effect on either lipogenic gene or protein expression suggesting that nutritional manipulation was not sufficient to rescue trans-10, cis-12 CLA-induced MFD. Finally, the effects of combination of a Rosiglitazone (ROSI), a PPAR-γ agonist, and trans-10, cis-12 CLA were examined on mammary and hepatic lipogenesis in lactating mice. Mammary lipogenesis was significantly reduced with trans-10, cis-12 CLA, reducing the milk fat content and mRNA expression of lipogenic transcription factors SREBP1-c and PPAR- γ. Trans-10, cis-12 CLA significantly increased hepatic lipid accumulation, while the mRNA expression of SREBP1-c and PPAR- γ were not altered. On the contrary, ROSI had no effects on mammary lipogenesis. However, ROSI significantly rescued trans-10, cis-12 CLA-induced hepatic steatosis. Advisors/Committee Members: Erdman, Richard A (advisor).

Subjects/Keywords: Animal sciences; Biochemistry; Nutrition; Conjugated linoleic acid; Dairy; Fatty acids; Lipid; Mammary; Milk fat

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Vyas, D. (2011). Denovo synthesized fatty acids as regulators of milk fat synthesis. (Thesis). University of Maryland. Retrieved from http://hdl.handle.net/1903/12306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vyas, Diwakar. “Denovo synthesized fatty acids as regulators of milk fat synthesis.” 2011. Thesis, University of Maryland. Accessed March 07, 2021. http://hdl.handle.net/1903/12306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vyas, Diwakar. “Denovo synthesized fatty acids as regulators of milk fat synthesis.” 2011. Web. 07 Mar 2021.

Vancouver:

Vyas D. Denovo synthesized fatty acids as regulators of milk fat synthesis. [Internet] [Thesis]. University of Maryland; 2011. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1903/12306.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vyas D. Denovo synthesized fatty acids as regulators of milk fat synthesis. [Thesis]. University of Maryland; 2011. Available from: http://hdl.handle.net/1903/12306

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

23. Ferreira, Evandro Maia. Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos.

Degree: PhD, Ciência Animal e Pastagens, 2011, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-20102011-105509/ ;

►

Três experimentos foram conduzidos com o objetivo de avaliar os efeitos do fornecimento de baixos teores de óleo de peixe em substituição parcial ao óleo… (more)

▼

Três experimentos foram conduzidos com o objetivo de avaliar os efeitos do fornecimento de baixos teores de óleo de peixe em substituição parcial ao óleo de soja, sobre o consumo de matéria seca (CMS), produção e perfil de ácidos graxos do leite de ovelhas, ganho médio diário de peso corporal (GMD), características da carcaça e composição de ácidos graxos da carne de cordeiros, digestibilidade dos nutrientes, características de fermentação ruminal e metabolismo ruminal dos ácidos graxos. Os tratamentos consistiram de uma dieta controle (CONT), sem adição de óleo; e 4 dietas adicionadas com 4,0% de óleo, consistindo de 0,0% (0P); 0,25% (25P); 0,50% (50P) e 0,75% de óleo de peixe (75P), com o óleo de soja completando o teor de 4,0% de óleo adicionado (% MS). No Experimento I a dieta controle foi composta por 70% de concentrado e 30% de volumoso, nos Experimentos II e III a dieta controle foi composta por 90% de concentrado e 10% de volumoso. Experimento I: Foram utilizadas 50 ovelhas, distribuídas em delineamento experimental de blocos completos casualizados. Verificouse aumento linear na produção de leite das ovelhas e no GMD das crias com a inclusão de óleo de peixe nas dietas. As concentrações de ácido vacênico, CLA C18:2 trans-10, cis-12, ácido eicosapentaenóico (EPA) e ácido docosahexaenóico (DHA) também aumentaram linearmente com os teores crescentes de inclusão de óleo de peixe. Experimento II: Foram utilizados 50 cordeiros, distribuídos em delineamento experimental de blocos completos casualizados. O CMS expresso em % do peso corporal (PC) e em g/kg de PC0,75 aumentou linearmente com os teores crescentes de inclusão de óleo de peixe, o que resultou em aumento linear no GMD dos cordeiros. A concentração de ácido esteárico reduziu com os teores crescentes de substituição do óleo de soja pelo óleo de peixe. Verificou-se aumento linear na concentração de ácido vacênico à medida que o óleo de peixe foi adicionado à dieta. Em comparação ao tratamento controle, os animais alimentados com as dietas contendo óleo de peixe apresentaram maior concentração de CLA C18:2 cis-9, trans-11 na carne. Experimento III: Foram utilizados cinco borregos, canulados no rúmen e no duodeno, distribuídos em delineamento experimental quadrado latino 5 x 5. A suplementação com as fontes de óleo reduziu a digestibilidade da PB. A concentração de acetato, butirato e dos ácidos graxos de cadeia curta (AGCC) totais foi maior no conteúdo ruminal dos animais alimentados com a dieta controle em relação aos das dietas contendo óleo, como conseqüência, o pH ruminal destes animais foi inferior. O fluxo duodenal de C18:1 trans-11 e CLA C18:2 cis-9, trans-11 foi superior para os animais que receberam gordura suplementar. Observou-se aumento linear no fluxo duodenal de ácido C18:1 trans-11 em resposta a inclusão de óleo de peixe nas dietas. A inclusão de 0,75% de óleo de peixe na dieta misturado à 3,25% de óleo de soja mostrou-se como a melhor alternativa avaliada.

Three trials were conducted to evaluate the effects of small amounts of fish oil…

Advisors/Committee Members: Pires, Alexandre Vaz.

Subjects/Keywords: Ácido linoléico; Ácidos graxos; Biohydrogenation; Conjugated linoleic acid; Dieta animal; Fatty acid; Óleo de peixe; Óleo de soja; Ovinos

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ferreira, E. M. (2011). Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/11/11139/tde-20102011-105509/ ;

Chicago Manual of Style (16^th Edition):

Ferreira, Evandro Maia. “Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos.” 2011. Doctoral Dissertation, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/11/11139/tde-20102011-105509/ ;.

MLA Handbook (7^th Edition):

Ferreira, Evandro Maia. “Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos.” 2011. Web. 07 Mar 2021.

Vancouver:

Ferreira EM. Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-20102011-105509/ ;.

Council of Science Editors:

Ferreira EM. Óleo de peixe em substituição parcial ao óleo de soja em dietas para ovinos. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/11/11139/tde-20102011-105509/ ;

Cal Poly

24. Fesler, Jeff. Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks.

Degree: MS, Animal Science, 2013, Cal Poly

URL: https://digitalcommons.calpoly.edu/theses/1172 ; 10.15368/theses.2013.234

► Conjugated linoleic acids (CLA) have been shown to have remarkable yet inconsistent metabolic effects in mice, rats, hamsters, chickens, cattle, and humans. In particular,… (more)

Subjects/Keywords: conjugated linoleic acid; body composition; adipose; duck; fatty acid synthase; acetyl Co-A carboxylase; Poultry or Avian Science

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fesler, J. (2013). Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks. (Masters Thesis). Cal Poly. Retrieved from https://digitalcommons.calpoly.edu/theses/1172 ; 10.15368/theses.2013.234

Chicago Manual of Style (16^th Edition):

Fesler, Jeff. “Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks.” 2013. Masters Thesis, Cal Poly. Accessed March 07, 2021. https://digitalcommons.calpoly.edu/theses/1172 ; 10.15368/theses.2013.234.

MLA Handbook (7^th Edition):

Fesler, Jeff. “Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks.” 2013. Web. 07 Mar 2021.

Vancouver:

Fesler J. Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks. [Internet] [Masters thesis]. Cal Poly; 2013. [cited 2021 Mar 07]. Available from: https://digitalcommons.calpoly.edu/theses/1172 ; 10.15368/theses.2013.234.

Council of Science Editors:

Fesler J. Conjugated linoleic acids alter body composition differently according to physiological age in Moulard ducks. [Masters Thesis]. Cal Poly; 2013. Available from: https://digitalcommons.calpoly.edu/theses/1172 ; 10.15368/theses.2013.234

Virginia Tech

25. Shafer, Brian David. Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content.

Degree: MS, Human Nutrition, Foods, and Exercise, 2006, Virginia Tech

URL: http://hdl.handle.net/10919/33835

► Dairy products are a primary source of c9, t11-CLA, an anti-carcinogenic agent, in the diet of humans. The t10, c12-CLA isomer, typically in trace amounts… (more)

Subjects/Keywords: Conjugated Linoleic Acid; Plasma Fatty Acid Concentrations; Functional Food

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Shafer, B. D. (2006). Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/33835

Chicago Manual of Style (16^th Edition):

Shafer, Brian David. “Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content.” 2006. Masters Thesis, Virginia Tech. Accessed March 07, 2021. http://hdl.handle.net/10919/33835.

MLA Handbook (7^th Edition):

Shafer, Brian David. “Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content.” 2006. Web. 07 Mar 2021.

Vancouver:

Shafer BD. Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content. [Internet] [Masters thesis]. Virginia Tech; 2006. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10919/33835.

Council of Science Editors:

Shafer BD. Concentrations of Conjugated Linoleic Acid Isomers in Human Plasma Reflect Intake of Dairy Products with Enhanced cis-9, trans-11 or tran-10, cis-12 Isomer Content. [Masters Thesis]. Virginia Tech; 2006. Available from: http://hdl.handle.net/10919/33835

26. Bortoleto, João Fernando. Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados.

Degree: PhD, Genética e Melhoramento de Plantas, 2010, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/11/11137/tde-26112010-145918/ ;

►

Plantas transgênicas constituem interessantes alternativas para a produção de compostos com elevado valor agregado como polímeros industriais, proteínas farmacológicas e lipídios nutracêuticos. Como candidata à… (more)

▼

Plantas transgênicas constituem interessantes alternativas para a produção de compostos com elevado valor agregado como polímeros industriais, proteínas farmacológicas e lipídios nutracêuticos. Como candidata à biofábrica, a cana-de-açúcar (Saccharum spp.) apresenta características agronômicas favoráveis, além de versatilidade de matéria-prima, que é empregada em fins tradicionais, como produção de álcool e açúcar, e até mesmo para geração de energia ou como forragem para alimentação de gado. Em nutrição animal, uma molécula bastante estudada é o ácido linoleico conjugado (CLA), que tem atividades anticarcinogênica, antidiabética, antiaterosclerose e moduladora do sistema imune e metabolismo de lipídios. O isômero t10,c12- CLA tem sido particularmente promissor na agropecuária por conta de inibição da síntese de gordura do leite e na melhoria do desempenho reprodutivo de vacas. Com o objetivo de avaliar a cana-de-açúcar como sistema biotecnológico para produção de CLA, o gene da isomerase do ácido linoleico de Propionibacterium acnes (pai) foi isolado e clonado, previamente caracterizado em Escherichia coli e, em seguida, utilizado na biolística de calos embriogênicos para regeneração de plantas transgênicas. No sistema procariótico, foi induzida a expressão de pai e a proteína heteróloga foi verificada como uma banda de 50 kDa, porém não houve alteração evidente do perfil de ácidos graxos da bactéria. Na cotransformação de cana-de-açúcar, o vetor pHA9, que contém o gene de seleção da neomicina fosfotransferase (nptII), foi bombardeado com uma das duas construções desenvolvidas com o promotor da poliubiquitina 1 de milho (pUbi1) dirigindo a expressão de pai adicionado ou não de sequência sinal da proteína de reparo de DNA recA para direcionamento para cloroplasto. Das cultivares CTC2 e IACSP9303046, foram obtidas eficiências de transformações de 2,2% e 1,7-7,1%, respectivamente. Um total de 156 plântulas foram regeneradas após regime de seleção com geneticina. Em seguida, 115 plântulas transgênicas foram identificadas por PCR para nptII e, entre essas, 29 e 48 foram PCRpositivas para pai e rec-pai, respectivamente. De 50 plantas aclimatizadas, 12 foram analisadas por Southern blot para nptII e 4 para pai, confirmando-se a transformação genética. Para comprovar a expressão de mRNA de pai, 27 plantas foram averiguadas por RT-PCR e RT-qPCR e indicaram produção de transcritos estudados. A análise de expressão das proteínas de folha por Western blot em 21 plantas selecionadas não produziu resultados conclusivos quanto à detecção de PAI. Essas mesmas foram analisadas por Cromatografia Gasosa, mas não foi detectado acúmulo de CLA. Embora seja possível a introdução e expressão do gene pai em cana-de-açúcar, é necessário avaliar em maior detalhe os fatores que possam afetar positivamente a produção de CLA, como tipo de tecido, compartimentos subcelulares para direcionamento proteico ou coexpressão de fosfolipases.

Transgenic plants are attractive alternatives for the production of high value compounds as industrial…

Advisors/Committee Members: Figueira, Antonio Vargas de Oliveira.

Subjects/Keywords: Ácido linoleico; Ácidos graxos; Biolistcs; Biolística; Biotecnologia de plantas; Cana-deaçúcar; Conjugated linoleic acid; Engenharia genética; Genetic transformation; Isômeros; Linoleic acid isomerase; Plantas transgênicas.

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Bortoleto, J. F. (2010). Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/11/11137/tde-26112010-145918/ ;

Chicago Manual of Style (16^th Edition):

Bortoleto, João Fernando. “Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados.” 2010. Doctoral Dissertation, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/11/11137/tde-26112010-145918/ ;.

MLA Handbook (7^th Edition):

Bortoleto, João Fernando. “Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados.” 2010. Web. 07 Mar 2021.

Vancouver:

Bortoleto JF. Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados. [Internet] [Doctoral dissertation]. University of São Paulo; 2010. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/11/11137/tde-26112010-145918/ ;.

Council of Science Editors:

Bortoleto JF. Modificação genética de cana-de-açúcar (Saccharum spp.) visando à produção de ácidos graxos conjugados. [Doctoral Dissertation]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/11/11137/tde-26112010-145918/ ;

Universidade do Rio Grande do Sul

27. Soares, Marcio Pereira. Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros.

Degree: 2012, Universidade do Rio Grande do Sul

URL: http://hdl.handle.net/10183/62058

►

O objetivo foi avaliar os efeitos da adição de diferentes concentrações dos isômeros cis-9, trans-11 e trans-10, cis-12 do ácido linoleico conjugado (CLA) ao meio… (more)

▼

O objetivo foi avaliar os efeitos da adição de diferentes concentrações dos isômeros cis-9, trans-11 e trans-10, cis-12 do ácido linoleico conjugado (CLA) ao meio de congelação sobre a motilidade espermática, a integridade da membrana plasmática, acrossomal e mitocondrial dos espermatozoides de touros. No experimento foram utilizados 4 touros Jersey, sendo os ejaculados processados na forma de “pool” (experimento 1) e individualmente (experimento 2). O meio base (MB) era constituído de tris (Dilutris®-SEMENCOM, Brasil) + 20 % de gema de ovo. Os tratamentos com CLA (Luta-CLA®-BASF, Brasil), tinham apresentação oleosa por isso foram preparados a partir do MB com adição de 1% de lauril sulfato de sódio (MBL). Os tratamentos foram compostos por: controle positivo (CP) = MB, controle negativo (CN) = MBL; tratamento 50 (T50) = MBL+50μM CLA; tratamento 100 (T100) = MBL+100μM CLA e tratamento 150 (T150) = MBL+150μM CLA. Após o descongelamento a qualidade espermática foi analisada pelo CASA, e a integridade das membranas plasmática, acrossomal e função mitocondrial através da associação das sondas PI, FITC-PSA, JC-1 e H-342. Em ambos os experimentos não foram observadas diferenças entre os tratamentos nas concentrações utilizadas, para os parâmetros avaliados, porém no experimento 2 houve diferenças entre indivíduos.

The objective was to evaluate the effects of addition of different concentrations of the isomers cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) to the freezing medium on sperm motility, the plasma membrane integrity, acrosomal and mitochondrial of bovine sperm. In the experiment, four Jersey bulls were used, and the ejaculates processed as "pool" (experiment 1) and individually (experiment 2). The diluent medium was based on tris (Dilutris®-SEMENCOM, Brazil) + 20% egg yolk (MB). The treatments with CLA (CLA-Luta®-BASF, Brazil), which had oily presentation, were prepared from MB with addition of 1% sodium lauryl sulfate (MBL). The treatments were: positive control (CP) = MB, negative control (CN) = MBL; treatment 50 (T50) = MBL+50μM CLA; treatment 100 (T100) = MBL+100μM CLA and treatment 150 (T150) = MBL+150μM CLA. After thawing the semen, the characteristics were analyzed by CASA, and the integrity of plasma and acrosomal membranes and mitochondrial function of sperm by association probes PI, FITC-PSA, JC-1 and H-342. In both experiments there were no differences between treatments and the conjugated linoleic acid (CLA), at the concentrations used, had no effect on the integrity and superior functionality of spermatozoa that underwent cryopreservation. However, but in experiment 2, there were differences between individuals.

Advisors/Committee Members: Brandelli, Adriano.

Subjects/Keywords: Bull; Touro; Semen; Sêmen animal; Criopreservação; Cryopreservation; Ácidos graxos; Fatty acids; Conjugated linoleic acid (CLA); Reproducao animal : Touros

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Soares, M. P. (2012). Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros. (Thesis). Universidade do Rio Grande do Sul. Retrieved from http://hdl.handle.net/10183/62058

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Soares, Marcio Pereira. “Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros.” 2012. Thesis, Universidade do Rio Grande do Sul. Accessed March 07, 2021. http://hdl.handle.net/10183/62058.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Soares, Marcio Pereira. “Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros.” 2012. Web. 07 Mar 2021.

Vancouver:

Soares MP. Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros. [Internet] [Thesis]. Universidade do Rio Grande do Sul; 2012. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/10183/62058.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Soares MP. Adição do ácido linoleico conjugado (cla) no diluidor de Congelação de sêmen de touros. [Thesis]. Universidade do Rio Grande do Sul; 2012. Available from: http://hdl.handle.net/10183/62058

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. Maria, Roberta Manzano. Análise do ácido linoléico conjugado em carne bovina por RMN.

Degree: Mestrado, Química Analítica, 2010, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17052010-082337/ ;

►

A carne bovina é considerada um alimento altamente nutritivo, sendo uma fonte de proteínas e vitaminas, além de minerais tal como ferro e zinco. Por… (more)

▼

A carne bovina é considerada um alimento altamente nutritivo, sendo uma fonte de proteínas e vitaminas, além de minerais tal como ferro e zinco. Por outro lado, a carne vermelha atualmente tem sido associada a doenças cardiovasculares e ao câncer. No entanto, essa associação vem sendo contestada, pois a carne de ruminantes bem como o leite são fontes naturais do ácido linoléico conjugado (CLA, do inglês \"conjugated linoleic acid\"), o qual possui várias propriedades benéficas, como atividade anticarcinogênica, redução de gordura corporal, entre outras. Essas propriedades têm sido observadas em estudos com animais modelos, mas também pesquisas apontam tais benefícios para os humanos. Vários estudos têm sido realizados para aumentar a produção de CLA pelos ruminantes no Brasil. Nesse contexto, se faz necessário o desenvolvimento de métodos rápidos e eficazes para a determinação de CLA em carnes de ruminantes e no leite, pois o método atual é baseado na análise dos ésteres metílicos dos ácidos graxos por cromatografia gasosa, que envolve várias etapas, sendo um método laborioso. Assim, o principal objetivo deste trabalho foi o desenvolvimento de uma metodologia rápida, baseada na técnica de ressonância magnética nuclear de hidrogênio (RMN de 1H) para a determinação do teor do CLA na gordura de carne bovina. Para isso foi avaliada a influência dos principais parâmetros experimentais de RMN de 1H, como a largura do pulso de radiofrequência, o tempo de repetição, método de excitação seletiva, entre outros parâmetros que podem interferir na razão sinal/ruído e na reprodutibilidade das medidas. Os resultados mostraram que a utilização da RMN de 1H para a determinação do teor de CLA em carne bovina, além de ser coerente com os dados obtidos por cromatografia gasosa, representa uma abordagem mais rápida e simples para a determinação do teor de CLA em carne bovina.

Beef is considered a very nutritive food, since it is a source of proteins and vitamins, besides minerals such as iron and zinc, on the other hand it has been associated to heart diseases and cancer. However, this association has been contested because ruminant meat as well as milk, is a natural source of conjugated linoleic acid (CLA), that has several benefic properties such as anticarcinogenic activity, reduction of body fat and others. These properties have been observed in studies with animals and can be extended to humans. Several studies have been done to increase the concentration of CLA in Brazilian ruminant meat. In this context, it is necessary to develop fast and effective analytical methods to determine CLA in ruminant meat and milk, because the current method, based on the analysis of fatty acid methyl esters by gas chromatography (GC), involves several stages, being laborious. Thus, the main purpose of this work was the development of a fast methodology, based on hydrogen nuclear magnetic resonance technique (1H NMR) to determine CLA content in beef fat. In consequence, it was evaluated the influence of main experimental parameters from 1H NMR,…

Advisors/Committee Members: Colnago, Luiz Alberto.

Subjects/Keywords: Ácido linoléico conjugado; Beef; Carne bovina; Conjugated linoleic acid; Nuclear magnetic resonance spectroscopy; Ressonância magnética nuclear

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Maria, R. M. (2010). Análise do ácido linoléico conjugado em carne bovina por RMN. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17052010-082337/ ;

Chicago Manual of Style (16^th Edition):

Maria, Roberta Manzano. “Análise do ácido linoléico conjugado em carne bovina por RMN.” 2010. Masters Thesis, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17052010-082337/ ;.

MLA Handbook (7^th Edition):

Maria, Roberta Manzano. “Análise do ácido linoléico conjugado em carne bovina por RMN.” 2010. Web. 07 Mar 2021.

Vancouver:

Maria RM. Análise do ácido linoléico conjugado em carne bovina por RMN. [Internet] [Masters thesis]. University of São Paulo; 2010. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17052010-082337/ ;.

Council of Science Editors:

Maria RM. Análise do ácido linoléico conjugado em carne bovina por RMN. [Masters Thesis]. University of São Paulo; 2010. Available from: http://www.teses.usp.br/teses/disponiveis/75/75132/tde-17052010-082337/ ;

29. Campos, Tarcila Beatriz Ferraz de. A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal.

Degree: Mestrado, Fisiologia Humana, 2008, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-04082008-151839/ ;

►

O ácido linoléico conjugado (CLA) é um ácido graxo poliinsaturado, encontrado nos produtos da alimentação. Estudos indicam que o CLA possui ações contra câncer, aterogênese… (more)

▼

O ácido linoléico conjugado (CLA) é um ácido graxo poliinsaturado, encontrado nos produtos da alimentação. Estudos indicam que o CLA possui ações contra câncer, aterogênese e DM 2 e obesidade. O presente trabalho avaliou os efeitos da suplementação crônica com CLA em ratos Wistar machos e teve como objetivo investigar o desenvolvimento corporal e o perfil metabólico dos animais e dos adipócitos isolados do tecido adiposo branco periepididimal. Após quatro semanas de suplementação os animais apresentaram redução no ritmo de ganho de peso, acompanhado de redução da ingestão alimentar, redução da massa adiposa e do volume celular dos adipócitos. A menor incorporação dos substratos acetato e glicose em lipídeos, o aumento lipólise e diminuição da expressão do PPAR?, também contribuíram para menor adiposidade encontrada. A redução de massa adiposa foi acompanhada por resistência à insulina, elevados níveis de citocinas inflamatórias e desenvolvimento de esteatose hepática. Esses fatores estão relacionados com o desenvolvimento de síndrome lipodistrófica em animais. Portanto, a efetividade do CLA em reduzir massa adiposa foi comprovada no presente estudo, mas os efeitos devem ser considerados.

Conjugated linoleic acid (CLA) is a natural polyunsatured fatty acid found in many dietary sources. Animal studies demonstrated that CLA has properties against cancer, atherogenesis, diabetes and obesity. This work evaluated the effects with chronic CLA supplementation in young adults Wistar male rats for four weeks, aiming to investigate the possible changes in corporal development and metabolic profile as well as the effects in isolated adipocytes of periepidydimal white adipose tissue of these supplemented animals. We observed a reduction of the rhythym of body weight gain, followed by diminished food intake, regression of adipose mass, and also a reduction of adipocyte volume. The findings of low incorporation of acetate and glucose substrates into lipids, elevation on the lipolytic response and reduction of PPAR-gamma gene expression, also contributed to the lower adiposity. This reduction in adipose mass was followed by insulin resistance, high levels of inflammatory citokines and the development of hepatic steatosis, features related to the development of lipodystrophic syndrome. Therefore, this study demonstrated the CLA effect on reduction of adipose mass, although adverse effects associated with CLA chronic supplementation must be considered.

Advisors/Committee Members: Lima, Fabio Bessa.

Subjects/Keywords: Ácido linoléico conjugado; Conjugated linoleic acid; Insulin resistance; Lipogênese; Lipogenesis; Lipólise; Lipolysis; Resistência à insulina; Tecido adiposo branco; White adipose tissue

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Campos, T. B. F. d. (2008). A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal. (Masters Thesis). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/42/42137/tde-04082008-151839/ ;

Chicago Manual of Style (16^th Edition):

Campos, Tarcila Beatriz Ferraz de. “A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal.” 2008. Masters Thesis, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/42/42137/tde-04082008-151839/ ;.

MLA Handbook (7^th Edition):

Campos, Tarcila Beatriz Ferraz de. “A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal.” 2008. Web. 07 Mar 2021.

Vancouver:

Campos TBFd. A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal. [Internet] [Masters thesis]. University of São Paulo; 2008. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-04082008-151839/ ;.

Council of Science Editors:

Campos TBFd. A suplementação crônica com ácido linoléico conjugado promove redução da massa adiposa e compromete a sensibilidade à insulina no tecido adiposo branco periepididimal. [Masters Thesis]. University of São Paulo; 2008. Available from: http://www.teses.usp.br/teses/disponiveis/42/42137/tde-04082008-151839/ ;

30. Carvalho, Eliane Bonifácio Teixeira de. Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos.

Degree: PhD, Bromatologia, 2011, University of São Paulo

URL: http://www.teses.usp.br/teses/disponiveis/9/9131/tde-12092012-111528/ ;

►

Ácidos graxos conjugados (AGCs) é o termo geral para descrever os isômeros posicionais e geométricos dos ácidos graxos poliinsaturados com duplas ligações conjugadas. Inúmeros efeitos… (more)

▼

Ácidos graxos conjugados (AGCs) é o termo geral para descrever os isômeros posicionais e geométricos dos ácidos graxos poliinsaturados com duplas ligações conjugadas. Inúmeros efeitos benéficos para a saúde como: anti-cancerígeno, anti-aterogênicos, anti-adipogênicos e anti-inflamatórios, tem sido atribuídos ao consumo dos AGCs. Entretanto, estudos sobre os efeitos dos AGCs no organismo ainda são inconclusivos e por isso o interesse em pesquisas visando a sua participação em processos fisiológicos. O objetivo deste estudo foi avaliar em ratos o efeito dos isômeros conjugados do ácido linoleico (9cis, 11trans e 10trans, 12cis) sobre o perfil lipídico tecidual e sua influência sobre parâmetros bioquímicos em processos oxidativos. Não foi possível detectar a atividade antioxidante in vitro dos CLAs. Os resultados obtidos demonstraram que o FFA-CLA foi capaz de reagir apenas com o radical DPPH. No experimento in vivo uma mistura comercial dos isômeros (9cis, 11trans e 10trans, 12 cis) foi utilizada como fonte de CLAs, e a influência da suplementação desses isômeros, foi avaliada e comparada com um grupo controle suplementado com água e com grupos experimentais suplementados com óleo de soja. O primeiro experimento foi realizado com animais Wistar saudáveis e teve duração de 40 dias, as amostras de ácidos graxos livres de CLAs, (FFACLAs) e óleo de soja foram fornecidas aos animais por meio de entubação orogástrica nas concentrações de 1%, 2% e 4% em relação ao consumo diário de dieta, o grupo controle recebeu 1% de água. A suplementação da dieta dos animais com os CLAs leva ao aumento nos níveis de triglicérides, mas não interfere nos parâmetros de estresse oxidativo, embora haja incorporação dose-dependente nos tecidos hepático, muscular e adiposo, não foram observadas alterações no volume das células adiposas, e na área e diâmetro do tecido muscular. No segundo experimento, com duração de 21 dias, ao avaliar o efeito da suplementação na dose de 2% de CLAs em ratos Wistar induzidos a peroxidação, pelo tratamento com tetracloreto de carbono. Pôde-se observar efeitos hepatoprotetor, dos CLAs atribuídos a sua prevenção na peroxidação lipídica e ao aumento da atividade das enzimas catalase (CAT), glutatina redutase (GR) e glutationa reduzida (GSH).

Conjugated fatty acids (CFAs) is the general term to describe positional and geometric isomers of polyunsaturated fatty acids with conjugated double bonds. Many beneficial health effects such as anti-cancer, anti-atherogenic, anti-adipogenic and anti-inflammatory, has been attributed to the consumption of the CFAs. However, studies on the effects of the CFAs in the body are still inconclusive and therefore the interest in research aimed at their participation in processes physiological. The objective of this study was to evaluate in rats the effect of conjugated linoleic acid isomers (9cis, 11trans and 10trans, 12cis) on lipid profile tissue and its effect on biochemical parameters in oxidative processes. It was not possible to detect the in vitro antioxidant activity of CLAs.…

Advisors/Committee Members: Mancini Filho, Jorge.

Subjects/Keywords: Ácido linoleico conjugado; Antioxidant activity; Atividade antioxidante; Carbon tetrachloride; Conjugated linoleic acid; Lipid Profile; Perfil Lipídico; Tetracloreto de carbono

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Carvalho, E. B. T. d. (2011). Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos. (Doctoral Dissertation). University of São Paulo. Retrieved from http://www.teses.usp.br/teses/disponiveis/9/9131/tde-12092012-111528/ ;

Chicago Manual of Style (16^th Edition):

Carvalho, Eliane Bonifácio Teixeira de. “Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos.” 2011. Doctoral Dissertation, University of São Paulo. Accessed March 07, 2021. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-12092012-111528/ ;.

MLA Handbook (7^th Edition):

Carvalho, Eliane Bonifácio Teixeira de. “Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos.” 2011. Web. 07 Mar 2021.

Vancouver:

Carvalho EBTd. Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos. [Internet] [Doctoral dissertation]. University of São Paulo; 2011. [cited 2021 Mar 07]. Available from: http://www.teses.usp.br/teses/disponiveis/9/9131/tde-12092012-111528/ ;.

Council of Science Editors:

Carvalho EBTd. Efeitos dos isômeros conjugados do ácido linoleico sobre a peroxidação lipídica em ratos. [Doctoral Dissertation]. University of São Paulo; 2011. Available from: http://www.teses.usp.br/teses/disponiveis/9/9131/tde-12092012-111528/ ;

		in
And / Or
		in
And / Or
		in
And / Or
		in

Open Access Theses and Dissertations