subject:( Quantitative)

1. Télot, Lorène. Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms.

Degree: Docteur es, Physiologie et biologie des organismes - populations - interactions. Biologie moléculaire, 2017, Sorbonne Paris Cité

URL: http://www.theses.fr/2017USPCC301

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L’ataxie de Friedreich (AF) est une maladie neurodégénérative à transmission autosomique récessive. Cette pathologie se caractérise par une dégénérescence spinocérébelleuse, une cardiomyopathie hypertrophique qui est… (more)

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L’ataxie de Friedreich (AF) est une maladie neurodégénérative à transmission autosomique récessive. Cette pathologie se caractérise par une dégénérescence spinocérébelleuse, une cardiomyopathie hypertrophique qui est la cause majeure du décès des patients, et un risque accru de diabète. La mutation majoritaire causant l’AF est une hyper-expansion de triplet GAA dans le premier intron du gène FXN codant la frataxine, une protéine mitochondriale ubiquitaire codée par le génome nucléaire. Ces hyper-expansions instables conduisent à une inhibition de la transcription du gène FXN et donc à une baisse d’expression de la frataxine. Aucun traitement curatif n’est disponible à l’heure actuelle pour cette maladie. Seule une meilleure compréhension de la physiopathologie de l’AF permettra d’envisager le développement de stratégies thérapeutiques efficaces. Plusieurs travaux montrent que la frataxine intervient dans la biosynthèse des centres Fe-S, mais son rôle exact dans cette voie, et sa possible contribution dans d’autres processus biochimiques, doivent encore être élucidés. Par une approche de protéomique quantitative utilisée pour la première fois sur des lignées lymphocytaires issues d’un patient AF et d’un individu non atteint, nous avons pu établir le profil d’expression des protéines associées à un déficit en frataxine. Ces nouvelles données confirment les processus altérés décrits pour l’AF, et ont permis la mise en exergue de nouveaux mécanismes mitochondriaux impactés, comme l’altération de la voie d’importation via CHCHD4. La mitochondrie interagissant avec le réticulum endoplasmique (RE), nous avons analysé et comparé l’impact d’un stress induit par la thapsigargine ciblant le RE sur le profil d’expression des protéines des lymphocytes B AF et contrôles. Ces analyses montrent que le déficit en frataxine rend les mitochondries des cellules de patients AF plus sensibles à un stress du RE, nécessitant la mise en place de réponses adaptatives spécifiques. L’approfondissement des mécanismes altérés associés au déficit en frataxine, avec et sans stress exogène, permettront d’une part, de mieux comprendre la pathogenèse de l’AF et d’autre part, de proposer des stratégies thérapeutiques adaptées.

Friedreich’s ataxia (FRDA) represents the most frequent type of autosomal-recessively inherited ataxia associated with a cardiomyopathy, which is the main cause of the death, and a risk of diabetes. FRDA is caused by mutations in the FXN gene, encoding mitochondrial frataxin, arising from an unstable hyperexpansion of GAA triplet repeats in the first intron of the gene. This hyperexpansion leads to FXN gene silencing and a quantitative decreased expression of frataxin. However despite many efforts to overcome any of these abnormalities, there is currently no efficient treatment to cure or even stop the progression of this disease, mostly because many aspects of the pathological consequences of frataxin depletion are still not fully understood. The precise role of frataxin is still under debate. A key function of frataxin in…

Advisors/Committee Members: Serre, Valérie (thesis director).

Subjects/Keywords: Protéomique quantitative; Proteomic quantitative approach

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Télot, L. (2017). Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms. (Doctoral Dissertation). Sorbonne Paris Cité. Retrieved from http://www.theses.fr/2017USPCC301

Chicago Manual of Style (16^th Edition):

Télot, Lorène. “Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms.” 2017. Doctoral Dissertation, Sorbonne Paris Cité. Accessed April 21, 2021. http://www.theses.fr/2017USPCC301.

MLA Handbook (7^th Edition):

Télot, Lorène. “Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms.” 2017. Web. 21 Apr 2021.

Vancouver:

Télot L. Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms. [Internet] [Doctoral dissertation]. Sorbonne Paris Cité; 2017. [cited 2021 Apr 21]. Available from: http://www.theses.fr/2017USPCC301.

Council of Science Editors:

Télot L. Pour une meilleure compréhension de la physiopathologie de l'Ataxie de Friedreich : apport de protéomique quantitative pour la caractérisation des mécanismes moléculaires altérés : For a better understanding of the physiopathology of Friedreich’ataxia : the contribution of quantitative proteomics for the characterization of altered molecular mechanisms. [Doctoral Dissertation]. Sorbonne Paris Cité; 2017. Available from: http://www.theses.fr/2017USPCC301

2. Cao, Lulu. Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways.

Degree: PhD, Chemistry, 2010, Brown University

URL: https://repository.library.brown.edu/studio/item/bdr:11036/

► Reversible protein phosphorylation plays a vital role in the regulation of cellular signaling pathways. With recent breakthrough developments in mass spectrometry-based proteomics technologies, including phosphopeptide… (more)

▼ Reversible protein phosphorylation plays a vital role in the regulation of cellular signaling pathways. With recent breakthrough developments in mass spectrometry-based proteomics technologies, including phosphopeptide enrichment and separation techniques, high-accuracy mass spectrometry and associated bioinformatics, MS-based quantitative phosphoproteomics have now gained great popularity. This technology has enabled the simultaneous identification and quantification of thousands of phosphorylation sites from entire phosphoproteomes. Mast cells play a central role in type I hypersensitivity reactions and allergic disorders such as anaphylaxis and asthma. In order to understand the molecular architecture underlying mast cell signaling, a systematic, quantitative analysis of the global tyrosine phosphorylation events triggered by activation of the mast cell receptor was performed. We have for the first time substantially characterized and quantified hundreds of tyrosine phosphorylation events in both mouse mast cell line MCP5 cells and mouse bone marrow-derived mast cells, with their temporal phosphorylation profiles providing preliminary insights into the newly discovered phosphorylation sites. However, this type of analysis does not provide enough information to make precise predictions of the placement of individual phosphorylation events within signaling pathways. Protein disruption and site-directed mutagenesis are essential to clearly define the precise biological roles of the newly discovered phosphorylation sites. To better understand the molecular mechanism underlying complex cellular signaling networks, we have also developed a hybrid quantitative approach that combines label free and SILAC quantification techniques. Label free quantification is applied to assemble high-density temporal data within a single cell type, either wide-type (WT) or mutant (Mut) cells, providing a list of phosphorylation sites that change in abundance after stimulation of a cellular receptor. SILAC quantification is then used to compare WT and Mut cells across a timecourse of receptor stimulation, providing direct information about how the newly observed phosphorylation sites respond to the mutagenesis. We have successfully applied this approach to ZAP-70 and SLP-76 deficient Jurkat T cell lines. These studies have provided great insights into the essential roles of these proteins in T cell signaling. Many hypotheses have been drawn and follow-up studies could provide directions for future investigation. Advisors/Committee Members: Salomon, Arthur (Director), Bazemore-Walker, Carthene (Reader), Peti, Wolfgang (Reader).

Subjects/Keywords: Quantitative Proteomics

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APA (6^th Edition):

Cao, L. (2010). Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways. (Doctoral Dissertation). Brown University. Retrieved from https://repository.library.brown.edu/studio/item/bdr:11036/

Chicago Manual of Style (16^th Edition):

Cao, Lulu. “Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways.” 2010. Doctoral Dissertation, Brown University. Accessed April 21, 2021. https://repository.library.brown.edu/studio/item/bdr:11036/.

MLA Handbook (7^th Edition):

Cao, Lulu. “Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways.” 2010. Web. 21 Apr 2021.

Vancouver:

Cao L. Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways. [Internet] [Doctoral dissertation]. Brown University; 2010. [cited 2021 Apr 21]. Available from: https://repository.library.brown.edu/studio/item/bdr:11036/.

Council of Science Editors:

Cao L. Quantitative Phosphoproteomic Analysis to Unravel Mast Cell and T Cell Signaling Pathways. [Doctoral Dissertation]. Brown University; 2010. Available from: https://repository.library.brown.edu/studio/item/bdr:11036/

West Virginia University

3. Weinstein, Ben. Development of an Emotional Pain Interview.

Degree: PhD, Psychology, 2011, West Virginia University

URL: https://doi.org/10.33915/etd.4813 ; https://researchrepository.wvu.edu/etd/4813

► This study developed and tested the Emotional Pain Interview (EPI), a semi-structured interview measuring emotional pain, using community dwelling adults with a significant history of… (more)

Subjects/Keywords: Quantitative psychology

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APA (6^th Edition):

Weinstein, B. (2011). Development of an Emotional Pain Interview. (Doctoral Dissertation). West Virginia University. Retrieved from https://doi.org/10.33915/etd.4813 ; https://researchrepository.wvu.edu/etd/4813

Chicago Manual of Style (16^th Edition):

Weinstein, Ben. “Development of an Emotional Pain Interview.” 2011. Doctoral Dissertation, West Virginia University. Accessed April 21, 2021. https://doi.org/10.33915/etd.4813 ; https://researchrepository.wvu.edu/etd/4813.

MLA Handbook (7^th Edition):

Weinstein, Ben. “Development of an Emotional Pain Interview.” 2011. Web. 21 Apr 2021.

Vancouver:

Weinstein B. Development of an Emotional Pain Interview. [Internet] [Doctoral dissertation]. West Virginia University; 2011. [cited 2021 Apr 21]. Available from: https://doi.org/10.33915/etd.4813 ; https://researchrepository.wvu.edu/etd/4813.

Council of Science Editors:

Weinstein B. Development of an Emotional Pain Interview. [Doctoral Dissertation]. West Virginia University; 2011. Available from: https://doi.org/10.33915/etd.4813 ; https://researchrepository.wvu.edu/etd/4813

University of Cape Town

4. Giuricich, Mario Nicolo. Index-linked catastrophe instrument valuation.

Degree: PhD, Division of Actuarial Science, 2018, University of Cape Town

URL: http://hdl.handle.net/11427/29642

► This thesis proposes four contributions to the literature on index-linked catastrophe instrument valuation. Invariably, any exercise to find index-linked catastrophe instrument prices involves three key… (more)

▼ This thesis proposes four contributions to the literature on index-linked catastrophe instrument valuation. Invariably, any exercise to find index-linked catastrophe instrument prices involves three key steps: construct a suitable arbitrage-free valuation model, estimate the parameters for the underlying loss process and simulate the instrument prices. Chapters 3 to 5 of this thesis loosely follow this process. In Chapter 3 we propose an index-linked catastrophe bond pricing model, which pervades in subsequent chapters. We furthermore show how, under certain assumptions, our model can use real-world catastrophe loss-data to find arbitrage-free, index-linked catastrophe bond prices. Chapter 4 demonstrates how we estimate parameters for the catastrophe-related insuranceloss process on which our pricing model relies. In practice, data from such insurance-loss processes is both left-truncated and heavy tailed. We build on ? ]’s procedure for modelling left-truncated data via a compound non-homogeneous Poisson process, and modify their fitting process so that it becomes systematically applicable in the context of heavy-tailed data. We close this chapter by presenting an importance sampling technique for simulating index-linked catastrophe bond prices. Chapter 5 treats the new problem of finding simple, closed-form expressions for indexlinked catastrophe bond prices. By using the weak convergence of compound renewal processes to α-stable Levy motion, we derive weak approximations to these catastrophe bond prices. ´ Their applicability is then highlighted in the context of our catastrophe-bond pricing model. Chapter 6 deviates from the ambit of catastrophe bond pricing, and considers a new type of insurance-linked security, namely the contingent convertible catastrophe bond. Our foremost contribution is that we comprehensively formalise the design and features of this instrument. Subsequently, we derive analytical valuation formulae for index-linked contingent-convertible catastrophe bonds. Using selected parameter values in line with earlier research, we empirically analyse our valuation formulae for index-linked contingent-convertible catastrophe bonds. Advisors/Committee Members: Burnecki, Krzysztof (advisor), Ouwehand, Peter (advisor), Platen, Eckhard (advisor).

Subjects/Keywords: Quantitative Finance

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APA (6^th Edition):

Giuricich, M. N. (2018). Index-linked catastrophe instrument valuation. (Doctoral Dissertation). University of Cape Town. Retrieved from http://hdl.handle.net/11427/29642

Chicago Manual of Style (16^th Edition):

Giuricich, Mario Nicolo. “Index-linked catastrophe instrument valuation.” 2018. Doctoral Dissertation, University of Cape Town. Accessed April 21, 2021. http://hdl.handle.net/11427/29642.

MLA Handbook (7^th Edition):

Giuricich, Mario Nicolo. “Index-linked catastrophe instrument valuation.” 2018. Web. 21 Apr 2021.

Vancouver:

Giuricich MN. Index-linked catastrophe instrument valuation. [Internet] [Doctoral dissertation]. University of Cape Town; 2018. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/11427/29642.

Council of Science Editors:

Giuricich MN. Index-linked catastrophe instrument valuation. [Doctoral Dissertation]. University of Cape Town; 2018. Available from: http://hdl.handle.net/11427/29642

5. Moura, Alban. Essays in Empirical Macroeconomics : Essais en macroéconomie empirique.

Degree: Docteur es, Sciences économiques, 2017, Université Toulouse I – Capitole

URL: http://www.theses.fr/2017TOU10017

► Cette thèse contribue à deux débats récurrents de la macroéconomie quantitative : la taille des multiplicateurs budgétaires pour le Chapitre 1 et les origines du… (more)

▼ Cette thèse contribue à deux débats récurrents de la macroéconomie quantitative : la taille des multiplicateurs budgétaires pour le Chapitre 1 et les origines du cycle des affaires pour les Chapitres 2 et 3. Les trois essais qui la composent partagent en outre un thème commun. Ils illustrent comment l'utilisation de modèles structurels enrichis permet, à l'aide des données macroéconomiques, d'améliorer certaines stratégies d'identification et d'obtenir des résultats parfois contraires aux théories établies. Le premier chapitre de la thèse étudie l'impact sur l'estimation des multiplicateurs budgétaires des mouvements endogènes dans les dépenses publiques aux Etats-Unis. Un modèle DSGE avec règles fiscales, estimé sur données trimestrielles, est utilisé pour identifier et quantifier les ajustements automatiques des dépenses de consommation publique. Les résultats confirment le rôle significatif de ces mouvements endogènes dans les données. Le modèle est ensuite employé comme laboratoire pour tester la qualité des multiplicateurs estimés par trois approches classiques : un modèle DSGE avec politique fiscale exogène, des modèles VARs identifiés par restrictions d'exogénéité et des modèles VARs identifiés par restrictions de signe. Ces expériences indiquent que les multiplicateurs estimés à l'aide de DSGEs sont plutôt robustes aux erreurs de spécification, tandis que ceux obtenus par VARs structurels peuvent être largement biaisés et imprécis. En particulier, les restrictions de signe apparaissent incapables de gérer correctement les problèmes d'endogénéité, alors même qu'elles ont été développées dans ce but. Le second chapitre, coécrit avec Paul Beaudry et Franck Portier, documente les propriétés empiriques de plusieurs mesures du prix relatif des biens d'investissement, une variable souvent utilisée pour identifier les chocs technologiques spécifiques au secteur de l'investissement. Les données étudiées proviennent en majorité des Etats-Unis, mais les autres pays du G7 sont également considérés. Deux faits stylisés émergent : (i) Le prix relatif de l'investissement n'est pas fortement contracyclique, contrairement à une idée répandue parmi les économistes. (ii) Il est même procyclique après 1985, et ce de manière significative, tout comme les prix relatifs des sous-composantes de l'investissement total. Ainsi, l'analyse agnostique des données contredit la théorie selon laquelle les chocs technologiques spécifiques au secteur de l'investissement, qui sont associés à des mouvements contracycliques du prix relatif, constituent la source majeure des fluctuations économiques dans les économies développées. A la place, les résultats suggèrent un rôle important pour les chocs affectant la demande en biens d'investissement. Le troisième et dernier chapitre étend l'analyse du Chapitre 2 en incorporant des rigidités de prix sur les biens d'investissement dans un modèle DSGE monétaire à deux secteurs. L'estimation du modèle sur données trimestrielles américaines, à l'aide de techniques bayésiennes, suggère que ces rigidités… Advisors/Committee Members: Portier, Franck (thesis director).

Subjects/Keywords: Macroéconomie quantitative

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APA (6^th Edition):

Moura, A. (2017). Essays in Empirical Macroeconomics : Essais en macroéconomie empirique. (Doctoral Dissertation). Université Toulouse I – Capitole. Retrieved from http://www.theses.fr/2017TOU10017

Chicago Manual of Style (16^th Edition):

Moura, Alban. “Essays in Empirical Macroeconomics : Essais en macroéconomie empirique.” 2017. Doctoral Dissertation, Université Toulouse I – Capitole. Accessed April 21, 2021. http://www.theses.fr/2017TOU10017.

MLA Handbook (7^th Edition):

Moura, Alban. “Essays in Empirical Macroeconomics : Essais en macroéconomie empirique.” 2017. Web. 21 Apr 2021.

Vancouver:

Moura A. Essays in Empirical Macroeconomics : Essais en macroéconomie empirique. [Internet] [Doctoral dissertation]. Université Toulouse I – Capitole; 2017. [cited 2021 Apr 21]. Available from: http://www.theses.fr/2017TOU10017.

Council of Science Editors:

Moura A. Essays in Empirical Macroeconomics : Essais en macroéconomie empirique. [Doctoral Dissertation]. Université Toulouse I – Capitole; 2017. Available from: http://www.theses.fr/2017TOU10017

University of Houston

6. Vu, Thai. Quantifying T cell Mediated Killing for Melanoma Immunotherapy.

Degree: MS, Chemical Engineering, 2014, University of Houston

URL: http://hdl.handle.net/10657/1684

► Adoptive cell therapy (ACT), based on the adoptive transfer of tumor-infiltrating lymphocytes (TILs) has well-recognized advantages such as (1) high specificity for target cells; (2)… (more)

Subjects/Keywords: Quantitative; Immunology

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APA (6^th Edition):

Vu, T. (2014). Quantifying T cell Mediated Killing for Melanoma Immunotherapy. (Masters Thesis). University of Houston. Retrieved from http://hdl.handle.net/10657/1684

Chicago Manual of Style (16^th Edition):

Vu, Thai. “Quantifying T cell Mediated Killing for Melanoma Immunotherapy.” 2014. Masters Thesis, University of Houston. Accessed April 21, 2021. http://hdl.handle.net/10657/1684.

MLA Handbook (7^th Edition):

Vu, Thai. “Quantifying T cell Mediated Killing for Melanoma Immunotherapy.” 2014. Web. 21 Apr 2021.

Vancouver:

Vu T. Quantifying T cell Mediated Killing for Melanoma Immunotherapy. [Internet] [Masters thesis]. University of Houston; 2014. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/10657/1684.

Council of Science Editors:

Vu T. Quantifying T cell Mediated Killing for Melanoma Immunotherapy. [Masters Thesis]. University of Houston; 2014. Available from: http://hdl.handle.net/10657/1684

7. Kinney, Deborah L. Examining Construct Stability Across Career Stage Cohorts.

Degree: MS, Psychology, 2011, Encompass Digital Archive, Eastern Kentucky University

URL: https://encompass.eku.edu/etd/15

► The purpose of this study is to evaluate construct stability of the same certification test taken at different points in a test taker's career,… (more)

Subjects/Keywords: Quantitative Psychology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kinney, D. L. (2011). Examining Construct Stability Across Career Stage Cohorts. (Masters Thesis). Encompass Digital Archive, Eastern Kentucky University. Retrieved from https://encompass.eku.edu/etd/15

Chicago Manual of Style (16^th Edition):

Kinney, Deborah L. “Examining Construct Stability Across Career Stage Cohorts.” 2011. Masters Thesis, Encompass Digital Archive, Eastern Kentucky University. Accessed April 21, 2021. https://encompass.eku.edu/etd/15.

MLA Handbook (7^th Edition):

Kinney, Deborah L. “Examining Construct Stability Across Career Stage Cohorts.” 2011. Web. 21 Apr 2021.

Vancouver:

Kinney DL. Examining Construct Stability Across Career Stage Cohorts. [Internet] [Masters thesis]. Encompass Digital Archive, Eastern Kentucky University; 2011. [cited 2021 Apr 21]. Available from: https://encompass.eku.edu/etd/15.

Council of Science Editors:

Kinney DL. Examining Construct Stability Across Career Stage Cohorts. [Masters Thesis]. Encompass Digital Archive, Eastern Kentucky University; 2011. Available from: https://encompass.eku.edu/etd/15

California State Polytechnic University – Pomona

8. Zuo, Yinjie. The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach.

Degree: MS, Economics, 2014, California State Polytechnic University – Pomona

URL: http://hdl.handle.net/10211.3/123925

► This paper analyses the dynamic macroeconomic effect of the 4 round Quantitative Easing (QE) adopted by the Federal Reserve (Fed) that started in November 2008.… (more)

Subjects/Keywords: quantitative easing

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APA (6^th Edition):

Zuo, Y. (2014). The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach. (Masters Thesis). California State Polytechnic University – Pomona. Retrieved from http://hdl.handle.net/10211.3/123925

Chicago Manual of Style (16^th Edition):

Zuo, Yinjie. “The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach.” 2014. Masters Thesis, California State Polytechnic University – Pomona. Accessed April 21, 2021. http://hdl.handle.net/10211.3/123925.

MLA Handbook (7^th Edition):

Zuo, Yinjie. “The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach.” 2014. Web. 21 Apr 2021.

Vancouver:

Zuo Y. The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach. [Internet] [Masters thesis]. California State Polytechnic University – Pomona; 2014. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/10211.3/123925.

Council of Science Editors:

Zuo Y. The Effect of Quantitative Easing to the U.S. Economy: Under TVP-VAR Approach. [Masters Thesis]. California State Polytechnic University – Pomona; 2014. Available from: http://hdl.handle.net/10211.3/123925

The Ohio State University

9. Sun, Yinghao. Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value.

Degree: PhD, Psychology, 2015, The Ohio State University

URL: http://rave.ohiolink.edu/etdc/view?acc_num=osu1449097866

► Item response theory (IRT) models are usually built on a set of statistical assumptions which may not necessarily hold in real data. Understanding the behavior… (more)

▼ Item response theory (IRT) models are usually built on a set of statistical assumptions which may not necessarily hold in real data. Understanding the behavior of IRT models in response to deviations from these assumptions can provide valuable information as how to apply IRT models in practice and how to interpret results. One way to study the behavior of IRT models when their assumptions do not hold exactly is through simulations, where data can be generated from a model constructed by deliberately violating some of the IRT model assumptions.This dissertation presents a method to perturb an IRT model so that its particular structure only holds approximately. The departure of the original IRT model from the perturbed model is operationalized by an exact value of model misfit. Meanwhile, maximum likelihood estimates (MLEs) of parameters in the original IRT model given data generated from the perturbed model converge almost surely to specified values. Therefore, starting from an IRT model with a set of specified parameter values, the proposed method allows us to construct a perturbed (or misspecified) IRT model such that MLEs remain unchanged and yet there is a specified degree of model misfit. It is then possible to construct a simulated environment where the original IRT model only holds approximately through generating data from the perturbed model.The proposed perturbation method can be formulated as a constrained optimization problem, which can be solved by several commonly available optimization routines, such as the interior-point method. Illustrated through a few simulation studies using the 1- and 2-parameter logistic model, it is shown that the perturbation method is working as expected, yielding specified estimates and specified model misfit values. Despite its application to IRT models in this dissertation, the perturbation method is generic and can be applied to a wide range of statistical models with different measures of model misfit. Advisors/Committee Members: Edwards, Michael (Advisor).

Subjects/Keywords: Quantitative Psychology

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APA (6^th Edition):

Sun, Y. (2015). Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value. (Doctoral Dissertation). The Ohio State University. Retrieved from http://rave.ohiolink.edu/etdc/view?acc_num=osu1449097866

Chicago Manual of Style (16^th Edition):

Sun, Yinghao. “Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value.” 2015. Doctoral Dissertation, The Ohio State University. Accessed April 21, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1449097866.

MLA Handbook (7^th Edition):

Sun, Yinghao. “Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value.” 2015. Web. 21 Apr 2021.

Vancouver:

Sun Y. Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value. [Internet] [Doctoral dissertation]. The Ohio State University; 2015. [cited 2021 Apr 21]. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1449097866.

Council of Science Editors:

Sun Y. Constructing a Misspecified Item Response Model That Yields a Specified Estimate and a Specified Model Misfit Value. [Doctoral Dissertation]. The Ohio State University; 2015. Available from: http://rave.ohiolink.edu/etdc/view?acc_num=osu1449097866

Rutgers University

10. Zhou, Anbo, 1991-. Understanding the functional impact of genomic variants.

Degree: PhD, Pipeline, 2020, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/64813/

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Structural variations (SV) can lead to DNA rearrangements and frequently cause diseases such as neurological disorders. SVs account for more total nucleotide changes and occur… (more)

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Structural variations (SV) can lead to DNA rearrangements and frequently cause diseases such as neurological disorders. SVs account for more total nucleotide changes and occur more frequently than single nucleotide polymorphisms (SNPs) (Stankiewicz and Lupski, 2010). As we continue to gain knowledge, SV has surpassed SNPs in its effects on human evolution, population diversity, and genetic diseases (Stankiewicz and Lupski, 2010). Compared to SNP, SV is more challenging to study due to its complex configuration, large size, and repetitive arrangement. Meanwhile, sequencing technologies including Illumina and Oxford Nanopore sequencing platform are being actively developed to generate sequencing data of human whole genomes, which can then be analyzed to study genetic variations. This series of studies aims to employ contemporary sequencing technologies and computational workflows to unravel the functional impact of SVs. Good tools are prerequisite to the successful execution of a job. My study starts from developing a pipeline construction tool called PipelineDog that can be used throughout the work. PipelineDog is a web-based integrated development environment (IDE) that represents a novel way to arrange and define workflows while promoting code scalability and reusability. I then apply established tools and workflows to analyze a 192-invidual cohort, surveying the large structural genetic etiology of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) co-occurrence. Lastly, the newly commercialized Nanopore sequencing technique was tested and evaluated on both existing and simulated data. The Nanopore sequencing is anticipated to improve the SV identification, as it generates longer reads and will enrich the SV determining evidence. I improved the overall SV identification accuracy by employing a random forest machine learning model to classify the combined dataset from different workflows. This analysis shed light on how to determine which SV identification workflow to use based on specific use cases for future projects.

Advisors/Committee Members: Veerzi, Mikeal (chair), Xing, Jinchuan (co-chair), Brzustowicz, Linda (internal member), Kwan, Kelvin (outside member), School of Graduate Studies.

Subjects/Keywords: Quantitative Biomedicine

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zhou, Anbo, 1. (2020). Understanding the functional impact of genomic variants. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/64813/

Chicago Manual of Style (16^th Edition):

Zhou, Anbo, 1991-. “Understanding the functional impact of genomic variants.” 2020. Doctoral Dissertation, Rutgers University. Accessed April 21, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/64813/.

MLA Handbook (7^th Edition):

Zhou, Anbo, 1991-. “Understanding the functional impact of genomic variants.” 2020. Web. 21 Apr 2021.

Vancouver:

Zhou, Anbo 1. Understanding the functional impact of genomic variants. [Internet] [Doctoral dissertation]. Rutgers University; 2020. [cited 2021 Apr 21]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64813/.

Council of Science Editors:

Zhou, Anbo 1. Understanding the functional impact of genomic variants. [Doctoral Dissertation]. Rutgers University; 2020. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64813/

11. Chasse, Brandon Michael. Relationship between Vividness of Visual Imagery and Self-Regulation.

Degree: 2018, Pacifica Graduate Institute

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=10824026

► Self-regulation is considered one of the most important operations of the human self and is correlated with multiple variables. The objective of this quantitative… (more)

Subjects/Keywords: Psychology; Quantitative psychology

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APA (6^th Edition):

Chasse, B. M. (2018). Relationship between Vividness of Visual Imagery and Self-Regulation. (Thesis). Pacifica Graduate Institute. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=10824026

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chasse, Brandon Michael. “Relationship between Vividness of Visual Imagery and Self-Regulation.” 2018. Thesis, Pacifica Graduate Institute. Accessed April 21, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=10824026.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chasse, Brandon Michael. “Relationship between Vividness of Visual Imagery and Self-Regulation.” 2018. Web. 21 Apr 2021.

Vancouver:

Chasse BM. Relationship between Vividness of Visual Imagery and Self-Regulation. [Internet] [Thesis]. Pacifica Graduate Institute; 2018. [cited 2021 Apr 21]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10824026.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chasse BM. Relationship between Vividness of Visual Imagery and Self-Regulation. [Thesis]. Pacifica Graduate Institute; 2018. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10824026

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Université de Grenoble

12. Von Essen, Christian. Quantitative Verification and Synthesis : Vérification et synthèse quantitative.

Degree: Docteur es, Informatique, 2014, Université de Grenoble

URL: http://www.theses.fr/2014GRENM090

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Cette thèse contribue à l'étude théorique et a l'application de la vérification et de la synthèse quantitative. Nous étudions les stratégies qui optimisent la fraction… (more)

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Cette thèse contribue à l'étude théorique et a l'application de la vérification et de la synthèse quantitative. Nous étudions les stratégies qui optimisent la fraction de deux récompenses des MDPs. L'objectif est la synthèse de régulateurs efficaces dans des environnements probabilistes. Premièrement nous montrons que les stratégies déterministes et sans mémoire sont suffisants. Sur la base de ces résultats, nous proposons trois algorithmes pour traiter des modèles explicitement encodées. Notre évaluation de ces algorithmes montre que l'un de ces derniers est plus rapide que les autres. Par la suite nous proposons et mettons en place une variante symbolique basé sur les diagrammes de décision binaire.Deuxièmement, nous étudions le problème de réparation des programmes d'un point de vue quantitatif. Cela conduit à une reformulation de la réparation d'un log: que seules les exécutions fautives du programme soient modifiées. Nous étudions les limites de cette approche et montrons comment nous pouvons assouplir cette nouvelle exigence. Nous concevons et mettons en œuvre un algorithme pour trouver automatiquement des réparations, et montrons qu'il améliore les modifications apportées aux programmes. Troisièmement, nous étudions une nouvelle approche au framework pour la vérification et synthèse quantitative. La vérification et la synthèse fonctionnent en tandem pour analyser la qualité d'un contrôleur en ce qui concerne, par exemple , de robustesse contre des erreurs de modélisation. Nous considérons également la possibilité d'approximer la courbure de Pareto, qui appataît de la combinaison du modèle avec de multiples récompenses. Cela nous permet à la fois d'étudier les compromis inhérents au système et de choisir une configuration adéquate. Nous appliquons notre framework aux plusieurs études de cas. La majorité de l'étude de cas est concernée par un système anti-collision embarqué (ACAS X). Nous utilisons notre framework pour aider à analyser l'espace de conception du système et de valider le contrôleur en cours d'investigation par la FAA. En particulier, nous contribuons l'analyse par PCTL et stochastic model checking.

This thesis contributes to the theoretical study and application of quantitative verification and synthesis. We first study strategies that optimize the ratio of two rewards in MDPs. The goal is the synthesis of efficient controllers in probabilistic environments. We prove that deterministic and memoryless strategies are sufficient. Based on these results we suggest 3 algorithms to treat explicitly encoded models. Our evaluation of these algorithms shows that one of these is clearly faster than the others. To extend its scope, we propose and implement a symbolic variant based on binary decision diagrams, and show that it cope with millions of states. Second, we study the problem of program repair from a quantitative perspective. This leads to a reformulation of program repair with the requirement that only faulty runs of the program be changed. We study the limitations of this approach and show how…

Advisors/Committee Members: Bensalem, Saddek (thesis director), Jobstmann, Barbara (thesis director).

Subjects/Keywords: Vérification quantitative; Synthèse quantitative; Systèmes adaptatifs; Quantitative Verification; Quantitative Synthesis; Adaptive Systems; Program Repair; 004

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Von Essen, C. (2014). Quantitative Verification and Synthesis : Vérification et synthèse quantitative. (Doctoral Dissertation). Université de Grenoble. Retrieved from http://www.theses.fr/2014GRENM090

Chicago Manual of Style (16^th Edition):

Von Essen, Christian. “Quantitative Verification and Synthesis : Vérification et synthèse quantitative.” 2014. Doctoral Dissertation, Université de Grenoble. Accessed April 21, 2021. http://www.theses.fr/2014GRENM090.

MLA Handbook (7^th Edition):

Von Essen, Christian. “Quantitative Verification and Synthesis : Vérification et synthèse quantitative.” 2014. Web. 21 Apr 2021.

Vancouver:

Von Essen C. Quantitative Verification and Synthesis : Vérification et synthèse quantitative. [Internet] [Doctoral dissertation]. Université de Grenoble; 2014. [cited 2021 Apr 21]. Available from: http://www.theses.fr/2014GRENM090.

Council of Science Editors:

Von Essen C. Quantitative Verification and Synthesis : Vérification et synthèse quantitative. [Doctoral Dissertation]. Université de Grenoble; 2014. Available from: http://www.theses.fr/2014GRENM090

Florida State University

13. Basik, Kevin J. (Kevin Joseph). Expanding the Boundaries of Behavioral Integrity in Organizations.

Degree: PhD, Management, 2010, Florida State University

URL: http://purl.flvc.org/fsu/fd/FSU_migr_etd-1125 ;

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Leaders' actions often speak louder than words, and when a pattern of incongruity between leaders' espoused values and their actions is perceived by subordinates, the… (more)

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Leaders' actions often speak louder than words, and when a pattern of incongruity between leaders' espoused values and their actions is perceived by subordinates, the individual and organizational consequences can be significant. Behavioral integrity (BI), defined as a perceived pattern of alignment (or misalignment) between a target's words and deeds (Simons, 2002: 19), has recently emerged as an interesting organizational construct, predicting a number of important outcomes. BI represents a potentially critical antecedent to trust formation, and may be an important cognitive mechanism in other related areas of interest (i.e., cynicism, deviant behavior, accountability, and political skill). This dissertation conceptually discusses potential antecedents to BI perceptions (i.e., managers' political skill and felt accountability intensity), and empirically examines the causal paths relating subordinates' BI perceptions to their trust in their managers, cynicism toward the organization, job satisfaction, organizational commitment, task performance, and deviant behavior. In addition, it proposed that organizational cynicism mediated the relationship between trust and attitudinal, but not behavioral, outcomes. The structural equation model confirmed BI's role as a significant antecedent of trust, which, in turn, was related to cynicism, commitment, and deviant behavior. In addition, cynicism demonstrated the hypothesized distinction between attitudinal and behavioral outcomes by mediating only the role between trust and both job satisfaction and commitment, but not between trust and deviant behavior or performance. This study answered a number of calls from different research streams, empirically tested BI relationships heretofore only conceptually proposed, and expanded the boundaries of BI literature to include cynicism and objectively-measured deviant behavior. Additionally, it provided further evidence for the unique role of organizational cynicism in trust-based outcomes. Finally, this study examined a number of exploratory constructs (i.e., effort, tension, political skill, and LMX) in an effort to initiate future BI-related research.

A Dissertation submitted to the Department of Management in partial fulfillment of the requirements for the degree of Doctor of Philosophy.

Summer Semester, 2010.

June 25, 2010.

Behavioral Integrity, Integrity, Leadership, Ethics, Deviant Behavior, Political Skill, Cynicism, Character

Gerald R. Ferris, Professor Directing Dissertation; Michael K. Brady, University Representative; Pamela L. Perrewé, Committee Member; Wayne A. Hochwarter, Committee Member.

Advisors/Committee Members: Gerald R. Ferris (professor directing dissertation), Michael K. Brady (university representative), Pamela L. Perrewé (committee member), Wayne A. Hochwarter (committee member).

Subjects/Keywords: Management; Quantitative research

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Basik, K. J. (. J. (2010). Expanding the Boundaries of Behavioral Integrity in Organizations. (Doctoral Dissertation). Florida State University. Retrieved from http://purl.flvc.org/fsu/fd/FSU_migr_etd-1125 ;

Chicago Manual of Style (16^th Edition):

Basik, Kevin J (Kevin Joseph). “Expanding the Boundaries of Behavioral Integrity in Organizations.” 2010. Doctoral Dissertation, Florida State University. Accessed April 21, 2021. http://purl.flvc.org/fsu/fd/FSU_migr_etd-1125 ;.

MLA Handbook (7^th Edition):

Basik, Kevin J (Kevin Joseph). “Expanding the Boundaries of Behavioral Integrity in Organizations.” 2010. Web. 21 Apr 2021.

Vancouver:

Basik KJ(J. Expanding the Boundaries of Behavioral Integrity in Organizations. [Internet] [Doctoral dissertation]. Florida State University; 2010. [cited 2021 Apr 21]. Available from: http://purl.flvc.org/fsu/fd/FSU_migr_etd-1125 ;.

Council of Science Editors:

Basik KJ(J. Expanding the Boundaries of Behavioral Integrity in Organizations. [Doctoral Dissertation]. Florida State University; 2010. Available from: http://purl.flvc.org/fsu/fd/FSU_migr_etd-1125 ;

Florida State University

14. Breaux, Denise Marie. An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice.

Degree: PhD, Management, 2010, Florida State University

URL: http://purl.flvc.org/fsu/fd/FSU_migr_etd-3059 ;

►

A recent trend in organizational research has shifted our focus toward dysfunctional behaviors in the workplace. We understand how and why many employees behave badly,… (more)

▼

A recent trend in organizational research has shifted our focus toward dysfunctional behaviors in the workplace. We understand how and why many employees behave badly, and we acknowledge that at times, supervisors are to blame. Abusive supervision represents one such body of literature describing the effects of hostile management on employees and organizations. Our knowledge of the outcomes of this type of supervision is sound and based on an increasingly large number of investigative studies. However, we still have little awareness of the reasons abusive supervision continues to occur. The present study sought to provide an enhanced understanding of the antecedents to abusive supervision. Building on the work of three previous studies and incorporating recent theoretical developments, this research examined the effects of justice violations, emotions, and subordinate behaviors on abusive supervision. Experimental findings indicated that supervisors' experiences of interpersonal justice from their own superiors determined their interpretations of and responses to subordinates' behaviors through an underlying emotional mechanism. In addition, this study provided support for the Affective Model of Justice Reasoning and introduced a new lens through which to view the entire process of abusive supervision. The implications include a deeper understanding of the reasons supervisors engage in behaviors that are detrimental to their employees and organizations, and a more informed picture of the far-reaching effects of organizational justice.

A Dissertation submitted to the Department of Management in partial fulfillment of the requirements for the degree of Doctor of Philosophy.

Spring Semester, 2010.

December 11, 2009.

Displaced Aggression, Anger, Emotions, Affect, Organizational Justice, Abusive Supervision

Pamela L. Perrewé, Professor Directing Dissertation; Robert Brymer, University Representative; Gerald R. Ferris, Committee Member; Jack T. Fiorito, Committee Member; Chad Van Iddekinge, Committee Member.

Advisors/Committee Members: Pamela L. Perrewé (professor directing dissertation), Robert Brymer (university representative), Gerald R. Ferris (committee member), Jack T. Fiorito (committee member), Chad Van Iddekinge (committee member).

Subjects/Keywords: Management; Quantitative research

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Breaux, D. M. (2010). An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice. (Doctoral Dissertation). Florida State University. Retrieved from http://purl.flvc.org/fsu/fd/FSU_migr_etd-3059 ;

Chicago Manual of Style (16^th Edition):

Breaux, Denise Marie. “An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice.” 2010. Doctoral Dissertation, Florida State University. Accessed April 21, 2021. http://purl.flvc.org/fsu/fd/FSU_migr_etd-3059 ;.

MLA Handbook (7^th Edition):

Breaux, Denise Marie. “An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice.” 2010. Web. 21 Apr 2021.

Vancouver:

Breaux DM. An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice. [Internet] [Doctoral dissertation]. Florida State University; 2010. [cited 2021 Apr 21]. Available from: http://purl.flvc.org/fsu/fd/FSU_migr_etd-3059 ;.

Council of Science Editors:

Breaux DM. An Experimental Investigation of Abusive Supervision as an Emotional Reaction to Injustice. [Doctoral Dissertation]. Florida State University; 2010. Available from: http://purl.flvc.org/fsu/fd/FSU_migr_etd-3059 ;

University of Kansas

15. Gu, Fei. Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model.

Degree: PhD, Psychology & Research in Education, 2013, University of Kansas

URL: http://hdl.handle.net/1808/15100

► In this work, two types of bootstrap methods are used to evaluate the absolute goodness-of-fit for the linear state space model. The first bootstrap is… (more)

Subjects/Keywords: Quantitative psychology; Psychometrics

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gu, F. (2013). Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model. (Doctoral Dissertation). University of Kansas. Retrieved from http://hdl.handle.net/1808/15100

Chicago Manual of Style (16^th Edition):

Gu, Fei. “Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model.” 2013. Doctoral Dissertation, University of Kansas. Accessed April 21, 2021. http://hdl.handle.net/1808/15100.

MLA Handbook (7^th Edition):

Gu, Fei. “Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model.” 2013. Web. 21 Apr 2021.

Vancouver:

Gu F. Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model. [Internet] [Doctoral dissertation]. University of Kansas; 2013. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/1808/15100.

Council of Science Editors:

Gu F. Using Parametric and Residual-based Bootstrap to Assess the Absolute Goodness-of-fit for State Space Model. [Doctoral Dissertation]. University of Kansas; 2013. Available from: http://hdl.handle.net/1808/15100

16. Fitzpatrick, Berne. Men in Groups| Attachment and Masculinity.

Degree: 2017, Pacifica Graduate Institute

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=10259251

► This quantitative study examines how attachment and masculinity influence men in their participation in social groups and support or therapy groups as measured by… (more)

Subjects/Keywords: Quantitative psychology; Gender studies

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Fitzpatrick, B. (2017). Men in Groups| Attachment and Masculinity. (Thesis). Pacifica Graduate Institute. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=10259251

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Fitzpatrick, Berne. “Men in Groups| Attachment and Masculinity.” 2017. Thesis, Pacifica Graduate Institute. Accessed April 21, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=10259251.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Fitzpatrick, Berne. “Men in Groups| Attachment and Masculinity.” 2017. Web. 21 Apr 2021.

Vancouver:

Fitzpatrick B. Men in Groups| Attachment and Masculinity. [Internet] [Thesis]. Pacifica Graduate Institute; 2017. [cited 2021 Apr 21]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10259251.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Fitzpatrick B. Men in Groups| Attachment and Masculinity. [Thesis]. Pacifica Graduate Institute; 2017. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10259251

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

17. Hallett, Elyse C. Reading without bounds| How different magnification methods affect the performance of students with low vision.

Degree: 2015, California State University, Long Beach

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=1601318

► Computer users with low vision must use additional methods to enlarge content in order to perceive content comfortably. One common method is a screen… (more)

Subjects/Keywords: Educational psychology; Quantitative psychology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Hallett, E. C. (2015). Reading without bounds| How different magnification methods affect the performance of students with low vision. (Thesis). California State University, Long Beach. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=1601318

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Hallett, Elyse C. “Reading without bounds| How different magnification methods affect the performance of students with low vision.” 2015. Thesis, California State University, Long Beach. Accessed April 21, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=1601318.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Hallett, Elyse C. “Reading without bounds| How different magnification methods affect the performance of students with low vision.” 2015. Web. 21 Apr 2021.

Vancouver:

Hallett EC. Reading without bounds| How different magnification methods affect the performance of students with low vision. [Internet] [Thesis]. California State University, Long Beach; 2015. [cited 2021 Apr 21]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=1601318.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Hallett EC. Reading without bounds| How different magnification methods affect the performance of students with low vision. [Thesis]. California State University, Long Beach; 2015. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=1601318

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Carnegie Mellon University

18. Qualizza, Andrea. Cutting Planes for Mixed Integer Programming.

Degree: 2011, Carnegie Mellon University

URL: http://repository.cmu.edu/dissertations/106

► My work focuses on cutting planes technology in Mixed Integer Programming. I explore novel classes of valid linear inequalities to strengthen linear relaxations of both… (more)

▼ My work focuses on cutting planes technology in Mixed Integer Programming. I explore novel classes of valid linear inequalities to strengthen linear relaxations of both Linear and Nonlinear Mixed Integer problems. My dissertation consists of three chapters that investigate theoretically and computationally the families of cuts considered. The first chapter is based on joint work with Prof. Pietro Belotti and Prof. Francois Margot. We study linear relaxations of Quadratically Constrained Quadratic Programs. The proposed relaxations are models with both semi-definite constraints (PSD) and linear constraints given by the Reformulation Linearization Technique (RLT). It is known from the literature (Anstreicher, 2007) that PSD and RLT used together yield better bounds than each technique used separately. We adopt a linear outer-approximation of the PSD cone, and we use exclusively linear programming tools to enforce the PSD condition via a cutting plane approach in the lifted space containing the Yij = xixj variables. We study new classes of valid linear inequalities and we test their effectiveness empirically. These include sparse PSD cuts and cuts derived from principal minors. Computational results based on instances from the GLOBALLib and Boxed Constrained Quadratic Programs show that this approach yields better bounds than using solely the standard PSD cuts on top of the RLT inequalities. The C++ code developed for this study has been included in Coin-OR as part of the Couenne project (exact solver for MINLPs). In the second chapter I present a work closely related to the recent developments in the area of \cuts from multiple rows of the simplex tableau" (Andersen et al., 2007). This chapter is based on joint work with Prof. Egon Balas. We generate intersection cuts from lattice-free convex sets as lift-and-project cuts from multiple-term disjunctions. We use the concept of \Disjunctive Hull" defined for a Mixed Integer Program at a fractional vertex v of its linear relaxation P as the convex hull of points in P satisfying all basic disjunctions that cut off v but no integer point. We examine the relationship between the Disjunctive Hull and the Integer Hull and we give procedures to generate inequalities for the Integer Hull derived from the Cut Generating Linear Program associated to the Disjunctive Hull. Strengthening techniques based on coefficient modularization and monoidal strengthening are also discussed. In this chapter we also analyze the case of 0-1 programming which has not been covered in the literature. Our framework applies to this setting with minor changes and produces valid families of cuts for the 0-1 case but invalid for general integer programs. These cuts include the triangle, quadrilateral, split cuts for the MIP case, and cuts from cones and truncated cones for the 0-1 setting. Moreover we run an experiment in which we separate two families of non facet defining cuts: we consider cuts from fixed shape triangles of type 1 and conic disjunctions having the apex at one vertex of the unit cube and…

Subjects/Keywords: Management Sciences and Quantitative Methods

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Qualizza, A. (2011). Cutting Planes for Mixed Integer Programming. (Thesis). Carnegie Mellon University. Retrieved from http://repository.cmu.edu/dissertations/106

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Qualizza, Andrea. “Cutting Planes for Mixed Integer Programming.” 2011. Thesis, Carnegie Mellon University. Accessed April 21, 2021. http://repository.cmu.edu/dissertations/106.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Qualizza, Andrea. “Cutting Planes for Mixed Integer Programming.” 2011. Web. 21 Apr 2021.

Vancouver:

Qualizza A. Cutting Planes for Mixed Integer Programming. [Internet] [Thesis]. Carnegie Mellon University; 2011. [cited 2021 Apr 21]. Available from: http://repository.cmu.edu/dissertations/106.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Qualizza A. Cutting Planes for Mixed Integer Programming. [Thesis]. Carnegie Mellon University; 2011. Available from: http://repository.cmu.edu/dissertations/106

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pittsburgh

19. Zigler, Christina Kelsey. The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes.

Degree: 2018, University of Pittsburgh

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=10692474

► The main goal of this project was to develop and provide validity evidence for a diseasespecific quality of life survey to be used with… (more)

Subjects/Keywords: Statistics; Health sciences; Quantitative psychology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Zigler, C. K. (2018). The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes. (Thesis). University of Pittsburgh. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=10692474

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zigler, Christina Kelsey. “The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes.” 2018. Thesis, University of Pittsburgh. Accessed April 21, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=10692474.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zigler, Christina Kelsey. “The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes.” 2018. Web. 21 Apr 2021.

Vancouver:

Zigler CK. The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes. [Internet] [Thesis]. University of Pittsburgh; 2018. [cited 2021 Apr 21]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10692474.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zigler CK. The Localized Scleroderma Quality of Life Instrument (LoSQI)| A Disease-Specific Survey Using Anchoring Vignettes. [Thesis]. University of Pittsburgh; 2018. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10692474

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of California – Riverside

20. Bannon, Brittany Lynn. Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood.

Degree: Psychology, 2017, University of California – Riverside

URL: http://www.escholarship.org/uc/item/3z62d72j

► The primary purpose of this dissertation was to examine age-related trajectories in illness behavior—or perceptions, evaluations, and responses to symptoms—across the late-life transition, the predictive… (more)

▼ The primary purpose of this dissertation was to examine age-related trajectories in illness behavior—or perceptions, evaluations, and responses to symptoms—across the late-life transition, the predictive role of perceived social support availability, and the extent to which illness behavior mediates the association of social support with subsequent functional decline. For Study 1, two large population-based samples were drawn from the Swedish Adoption/Twin Study of Aging (SATSA) and the Sex Differences in Health and Aging study (GENDER) to examine longitudinal measurement invariance in illness behavior. The extent to which social support availability from friends versus family members predicted reduced levels and change in illness behavior across 17 years from mid- to late-adulthood in SATSA was also examined. Confirmatory factor analyses supported strict factorial invariance in the illness behavior factor across four waves in SATSA, whereas partial, weak factorial invariance was supported in GENDER. Latent growth models suggested, a small, linear increase in illness behavior across age, and perceived support from friends and family both predicted reduced levels of illness behavior—but not change—after controlling for sex, comorbidity, SES, marital status, and age at study entry. For Study 2, age-related change in functional difficulty was evaluated across 23 years in SATSA, as well as the extent to which social support availability (again, from friends versus family) buffered decline. Additionally, longitudinal mediation models evaluated the extent to which illness behavior explained the association between social support availability and subsequent functional status and change. Overall, findings suggested piecewise growth in functional difficulty, with stability prior to age 75 and a linear increase afterward. Higher family support availability predicted faster decline, whereas friend support was not associated. Furthermore, illness behavior status mediated the association between social support availability and functional status; whereas intra-individual growth in illness behavior separately predicted a faster rate of functional decline. Collectively, these results suggest that illness behavior, as a unifying individual difference construct, exhibits systematic intra-individual change and significant variability during the transition to late adulthood, and represents a potentially important mediating and independent pathway linking perceived social support availability with subsequent physical functioning.

Subjects/Keywords: Social psychology; Quantitative psychology; Aging

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APA (6^th Edition):

Bannon, B. L. (2017). Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood. (Thesis). University of California – Riverside. Retrieved from http://www.escholarship.org/uc/item/3z62d72j

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bannon, Brittany Lynn. “Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood.” 2017. Thesis, University of California – Riverside. Accessed April 21, 2021. http://www.escholarship.org/uc/item/3z62d72j.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bannon, Brittany Lynn. “Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood.” 2017. Web. 21 Apr 2021.

Vancouver:

Bannon BL. Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood. [Internet] [Thesis]. University of California – Riverside; 2017. [cited 2021 Apr 21]. Available from: http://www.escholarship.org/uc/item/3z62d72j.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bannon BL. Psychosocial Pathways and Functional Consequences of Illness Behavior Trajectories Across Late Adulthood. [Thesis]. University of California – Riverside; 2017. Available from: http://www.escholarship.org/uc/item/3z62d72j

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Cornell University

21. Larsson, Sara. Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize.

Degree: PhD, Plant Breeding, 2013, Cornell University

URL: http://hdl.handle.net/1813/33936

► Maize (Zea mays L.) is an important crop and an excellent model organism to study genetic systems. It captures remarkable diversity, which can be observed… (more)

▼ Maize (Zea mays L.) is an important crop and an excellent model organism to study genetic systems. It captures remarkable diversity, which can be observed on both the genotypic and phenotypic level. Because of its diversity, maize responded very effectively to artificial selection during domestication and improvement. Maize adapted to very diverse environments. This adaptation has been possible through heritable changes in flowering time, responses to photoperiod and temperature, and plant architecture. Understanding the underlying architecture of these traits will allow us to utilize all the variation offered and increase productivity for a more sustainable agriculture. The following studies focus on analysis of three different traits. First, is a reanalysis of one of the first generation structured association mapping studies of the Dwarf8 locus with flowering time, using new mapping populations and statistical approaches. This trait is highly correlated with population structure, and we found that basic structured association methods overestimate the phenotypic effect in the region, while mixed model approaches perform better. Combined with analysis of the maize NAM population, it is concluded that the QTL effects at the general location of the d8 locus are from extended haplotypes and that d8 is not associated with flowering time. Second, hybrids were developed using the NAM inbred population crossed to a common tester to examine hybrid vigor in terms of plant height and flowering time, as well as yield. A number of QTL were identified for all three traits using joint linkage mapping. Additionally, reasonable prediction accuracies (~0.55) were obtained using ridge regression in the hybrids. This study gives us a better understanding of yield and hybrid vigor. Last, damage caused by lodging is a significant problem in maize production, resulting in 5-20 % annual loss in yield. In this study, more than 1,500 diverse inbred lines crossed to a common tester were evaluated across multiple environments. Due to a large sample size and despite multiple environments with lodging events occurring at different points in time, we were able to utilize joint linkage mapping to identify a number of QTL with small effects for lodging. Advisors/Committee Members: Buckler, Edward S (chair), Setter, Timothy Lloyd (committee member), Smith Einarson, Margaret Elizabeth (committee member).

Subjects/Keywords: maize; quantitative geneics; hybrids

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Larsson, S. (2013). Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/33936

Chicago Manual of Style (16^th Edition):

Larsson, Sara. “Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize.” 2013. Doctoral Dissertation, Cornell University. Accessed April 21, 2021. http://hdl.handle.net/1813/33936.

MLA Handbook (7^th Edition):

Larsson, Sara. “Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize.” 2013. Web. 21 Apr 2021.

Vancouver:

Larsson S. Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize. [Internet] [Doctoral dissertation]. Cornell University; 2013. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/1813/33936.

Council of Science Editors:

Larsson S. Analysis Of Flowering Time, Hybrid Vigor, Yield, And Lodging In Maize. [Doctoral Dissertation]. Cornell University; 2013. Available from: http://hdl.handle.net/1813/33936

Vanderbilt University

22. Chumbley, Chad Walter. Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens.

Degree: PhD, Chemistry, 2016, Vanderbilt University

URL: http://hdl.handle.net/1803/11346

► Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) allows for the high-throughput analysis of plasma samples for pharmaceutical drugs. A new multiplexing time-of-flight instrument with a… (more)

▼ Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) allows for the high-throughput analysis of plasma samples for pharmaceutical drugs. A new multiplexing time-of-flight instrument with a continuous raster laser was used to improve the accurate quantitation of drugs in plasma samples using internal standards. This instrument has the capability of isolating and fragmenting multiple analytes of interest from a single laser shot. Quantitative assays of plasma for enalapril using ramipril as the internal standard and for verapamil, enalapril, and promethazine with their respective isotopically labeled internal standards were developed using this instrumentation. Verapamil, enalapril, and ramipril are all drugs used to treat hypertension, while promethazine is an antihistamine. The quantitative accuracies and precision for each analyte improved greatly upon normalization to their respective internal standard. MALDI imaging mass spectrometry (IMS) allows for the elucidation of the distribution of pharmaceutical drugs within tissue sections. Absolute pixel-to-pixel quantitation by MALDI IMS is challenging because of matrix and tissue heterogeneities. Through careful application of isotopically labeled internal standards, accurate quantitative results can be obtained. A homogenously dosed standard tissue was developed to assess different methods of internal standard application. Internal standards with calibration standards on an adjacent non-dosed section were then used to quantitatively determine the distributions of rifampicin, an antibiotic used to treat tuberculosis, and of promethazine when dosed in animal models. The quantitative distribution of rifampicin was elucidated in rabbit livers, while the quantitative distribution of promethazine was elucidated in mouse livers and kidneys. The MALDI IMS data were compared to conventional quantitation methods using HPLC-MS/MS for further validation. The results from all experiments compared favorably to HPLC-MS/MS (>90% similarities), but quantitative MALDI IMS provided the localization of the drugs within the tissue sections. This information is lost when homogenizing the tissue for HPLC-MS/MS analysis. These studies allow for the direct quantitation of pharmaceutical drugs in relation to histological and anatomical features within tissue sections, providing unparalleled information about drugs and their targets. Advisors/Committee Members: John A. McLean (committee member), Kevin L. Schey (committee member), David E. Cliffel (committee member), Richard M. Caprioli (Committee Chair).

Subjects/Keywords: MALDI IMS; MALDI MS; Quantitative

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APA (6^th Edition):

Chumbley, C. W. (2016). Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11346

Chicago Manual of Style (16^th Edition):

Chumbley, Chad Walter. “Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens.” 2016. Doctoral Dissertation, Vanderbilt University. Accessed April 21, 2021. http://hdl.handle.net/1803/11346.

MLA Handbook (7^th Edition):

Chumbley, Chad Walter. “Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens.” 2016. Web. 21 Apr 2021.

Vancouver:

Chumbley CW. Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens. [Internet] [Doctoral dissertation]. Vanderbilt University; 2016. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/1803/11346.

Council of Science Editors:

Chumbley CW. Absolute Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Imaging Mass Spectrometry of Pharmaceutical Drugs from Biological Specimens. [Doctoral Dissertation]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/11346

23. Sharma, Aditya. Heterosis its components and inheritance studies of some quantitative characters in mungbean;.

Degree: Agriculture Botany, 2014, Chaudhary Charan Singh University

URL: http://shodhganga.inflibnet.ac.in/handle/10603/19528

Heterosis its components and inheritance studies of some quantitative characters in mungbean newline

Advisors/Committee Members: Sharma, S. P..

Subjects/Keywords: inheritance studies; quantitative characters; mungbean

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APA (6^th Edition):

Sharma, A. (2014). Heterosis its components and inheritance studies of some quantitative characters in mungbean;. (Thesis). Chaudhary Charan Singh University. Retrieved from http://shodhganga.inflibnet.ac.in/handle/10603/19528

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Sharma, Aditya. “Heterosis its components and inheritance studies of some quantitative characters in mungbean;.” 2014. Thesis, Chaudhary Charan Singh University. Accessed April 21, 2021. http://shodhganga.inflibnet.ac.in/handle/10603/19528.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Sharma, Aditya. “Heterosis its components and inheritance studies of some quantitative characters in mungbean;.” 2014. Web. 21 Apr 2021.

Vancouver:

Sharma A. Heterosis its components and inheritance studies of some quantitative characters in mungbean;. [Internet] [Thesis]. Chaudhary Charan Singh University; 2014. [cited 2021 Apr 21]. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/19528.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sharma A. Heterosis its components and inheritance studies of some quantitative characters in mungbean;. [Thesis]. Chaudhary Charan Singh University; 2014. Available from: http://shodhganga.inflibnet.ac.in/handle/10603/19528

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

24. Soomro, Wali M 1966-. Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada.

Degree: 2016, University of Saskatchewan

URL: http://hdl.handle.net/10388/7655

► Blackleg of canola, caused by Leptosphaeria maculans (Desmaz.) Ces. & de Not, is a serious concern in western Canada. The disease had been managed successfully… (more)

▼ Blackleg of canola, caused by Leptosphaeria maculans (Desmaz.) Ces. & de Not, is a serious concern in western Canada. The disease had been managed successfully since 1990s with use of resistant cultivars and extended crop rotations until recent years when both blackleg incidence and severity increased noticeably. This may be attributed to changes in the pathogen population that erodes the resistance of canola cultivars. The resistance associated with Canadian canola (Brassica napus L.) cultivars (CCCs) in Canada is not clearly understood. The current study was conducted to investigate the race structure of L. maculans in commercial canola fields and determine its role in blackleg incidence and severity. In addition, resistance (R) genes in representative CCCs were characterized to understand their role in blackleg control against the current population of L. maculans. A total of 372 L. maculans isolates collected from 16 canola fields with different levels of blackleg severity in 2012 and 2013 were analysed for the presence or absence of particular avirulence (Avr) alleles by inoculating 12 lines of a host differential set with known R genes. The results indicated that the alleles AvrLm1, AvrLm3, AvrLm9 and AvrLep2 were at very low or undetectable levels in these fields, while AvrLm2, AvrLm4, AvrLm6 and AvrLm7 were generally common. Since only the R genes Rlm1 and Rlm3 are found commonly in CCCs, this result indicates that most of our cultivars are no longer effective against the current pathogen population on the prairies.Variation in Avr gene frequency was observed, depending on the cultivar, field or region studied, but these differences alone appeared insufficient to explain the variability in blackleg severity in these fields, and the erosion of Rlm1 and Rlm3 would unlikely be the primary cause of isolated blackleg outbreaks for most of the fields investigated. Advisors/Committee Members: Peng, Gary, Kutcher, Randy H, Banniza, Sabine, Booker, Helen, Warkentin , Tom.

Subjects/Keywords: Blackleg; Leptospsphaeria maculans quantitative resistance

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APA (6^th Edition):

Soomro, W. M. 1. (2016). Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7655

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Soomro, Wali M 1966-. “Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada.” 2016. Thesis, University of Saskatchewan. Accessed April 21, 2021. http://hdl.handle.net/10388/7655.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Soomro, Wali M 1966-. “Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada.” 2016. Web. 21 Apr 2021.

Vancouver:

Soomro WM1. Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada. [Internet] [Thesis]. University of Saskatchewan; 2016. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/10388/7655.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Soomro WM1. Characterizing Avr genes of Leptosphaeria maculans and resistance responses among Canadian canola cultivars in western Canada. [Thesis]. University of Saskatchewan; 2016. Available from: http://hdl.handle.net/10388/7655

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Stellenbosch University

25. Visser, Cobus. A micro approach to quantitative dehydration sensor development.

Degree: MEng, Mechanical and Mechatronic Engineering, 2015, Stellenbosch University

URL: http://hdl.handle.net/10019.1/97137

►

ENGLISH ABSTRACT: The assessment of dehydration is an ever elusive golden standard, even given the plethora of hydration markers that exist to date. Many literature… (more)

▼

ENGLISH ABSTRACT: The assessment of dehydration is an ever elusive golden standard, even given the plethora of hydration markers that exist to date. Many literature sources acknowledge the need for a portable device that can be used as an indicative tool for hydration. This project sought to find a solution for assessing dehydration on a micro level looking for an indication of hydration by investigating the levels of water concentration in the skin and water compartments of the body using bioelectrical impedance, stratum corneum impedance and infrared spectrometry. Two studies were conducted to evaluate the efficacy of these devices: an infield study to assess the efficacy of the devices for measuring dehydration brought on by exercise in adults and an infant study where the devices where used to assess its ability to measure dehydration in infants who have succumbed to diarrhoea. The studies showed that the devices are not applicable in measuring real time hydration in exercising subjects as sweat was a perturbing factor in the measurements. The infant study provided promising results with regards to the usage of the infrared device. It is believed that these results could spur further investigation into the field of using infrared spectrometry as a dehydration marker. Dehydration still remains to be an ever elusive standard but the importance of finding a solution to quantitatively assess hydration is a field which could benefit the general population and its importance should not be underestimated.

AFRIKAANSE OPSOMMING: Die assessering van dehidrasie is steeds 'n ontwykende goue standaard selfs gegewe die oorvloed van hidrasiemerkers wat bestaan tot op datum. Baie literatuurbronne erken egter die behoefte aan 'n draagbare toestel wat as 'n hulpmiddel kan dien vir die evaluering van die vlakke van dehidrasie. Hierdie projek streef daarna om ondersoek in te stel tot die assessering van dehidrasie op 'n mikrovlak deur die waterkonsentrasies te meet in die vel en die verskeie waterkompartemente in die liggaam via die gebruik van bio-elektriese impedansie analise, stratum corneum impedansie analise en infrarooi-spektrometrie. Twee studies is gedoen om die doeltreffendheid van die toestelle te evalueer: 'n inveldstudie wat die hidrasievlakke van volwassenes meet wat ly aan dehidrasie weens oefening en 'n studie wat dehidrasie meet in neonate wat ly aan dehidrasie weens diarree. Die studies het bewyse gelewer dat die toestelle nie effektief is met betrekking tot die meet van dehidrasie in aktiewe volwassenes nie, weens die rede dat sweet 'n verstorende faktor is. Die neonate studie het belowende resultate verskaf met betrekking tot die gebruik van die infrarooi toestel. Daar word geglo dat hierdie resultate verdere ondersoek in die veld met betrekking tot infrarooi spektrometrie as 'n hidrasie merker kan motiveer. Finale bevindinge wys dat die kwantifisering van dehidrasie steeds 'n ontwykende standaard is, maar die belangrikheid van 'n moontlike oplossing sal voordelig wees vir…

Advisors/Committee Members: Scheffer, C., Stellenbosch University. Faculty of Engineering. Dept. of Mechanical and Mechatronic Engineering..

Subjects/Keywords: Quantitative dehydration sensor – Development; UCTD

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APA (6^th Edition):

Visser, C. (2015). A micro approach to quantitative dehydration sensor development. (Thesis). Stellenbosch University. Retrieved from http://hdl.handle.net/10019.1/97137

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Visser, Cobus. “A micro approach to quantitative dehydration sensor development.” 2015. Thesis, Stellenbosch University. Accessed April 21, 2021. http://hdl.handle.net/10019.1/97137.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Visser, Cobus. “A micro approach to quantitative dehydration sensor development.” 2015. Web. 21 Apr 2021.

Vancouver:

Visser C. A micro approach to quantitative dehydration sensor development. [Internet] [Thesis]. Stellenbosch University; 2015. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/10019.1/97137.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Visser C. A micro approach to quantitative dehydration sensor development. [Thesis]. Stellenbosch University; 2015. Available from: http://hdl.handle.net/10019.1/97137

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University

26. Marceau, Kristine P. Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior .

Degree: 2011, Penn State University

URL: https://submit-etda.libraries.psu.edu/catalog/11641

► Pubertal development is a socially salient, physiological process that may impact concurrent internalizing problems via physiological, genetic and/or environmental pathways. The present study uses two… (more)

Subjects/Keywords: Puberty; Quantitative Genetics; Internalizing

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APA (6^th Edition):

Marceau, K. P. (2011). Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior . (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/11641

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Marceau, Kristine P. “Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior .” 2011. Thesis, Penn State University. Accessed April 21, 2021. https://submit-etda.libraries.psu.edu/catalog/11641.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Marceau, Kristine P. “Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior .” 2011. Web. 21 Apr 2021.

Vancouver:

Marceau KP. Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior . [Internet] [Thesis]. Penn State University; 2011. [cited 2021 Apr 21]. Available from: https://submit-etda.libraries.psu.edu/catalog/11641.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Marceau KP. Pubertal Maturation as a Moderator of Genetic and Environmental Influences on Internalizing Behavior . [Thesis]. Penn State University; 2011. Available from: https://submit-etda.libraries.psu.edu/catalog/11641

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Pretoria

27. Sham, Tsz Ching Emic. Determining whether active investment, using a combination of investment styles, out-performs passive investment.

Degree: MBA, Gordon Institute of Business Science (GIBS), 2014, University of Pretoria

URL: http://hdl.handle.net/2263/43995

► The objective of this research paper was to examine the possibility of active investment out-performing the passive investment by using a combination-based investment style for… (more)

Subjects/Keywords: UCTD; Investments; Quantitative research

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APA (6^th Edition):

Sham, T. C. E. (2014). Determining whether active investment, using a combination of investment styles, out-performs passive investment. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/43995

Chicago Manual of Style (16^th Edition):

Sham, Tsz Ching Emic. “Determining whether active investment, using a combination of investment styles, out-performs passive investment.” 2014. Masters Thesis, University of Pretoria. Accessed April 21, 2021. http://hdl.handle.net/2263/43995.

MLA Handbook (7^th Edition):

Sham, Tsz Ching Emic. “Determining whether active investment, using a combination of investment styles, out-performs passive investment.” 2014. Web. 21 Apr 2021.

Vancouver:

Sham TCE. Determining whether active investment, using a combination of investment styles, out-performs passive investment. [Internet] [Masters thesis]. University of Pretoria; 2014. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/2263/43995.

Council of Science Editors:

Sham TCE. Determining whether active investment, using a combination of investment styles, out-performs passive investment. [Masters Thesis]. University of Pretoria; 2014. Available from: http://hdl.handle.net/2263/43995

University of Pretoria

28. Meloa, Tebogo. The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets.

Degree: Gordon Institute of Business Science (GIBS), 2014, University of Pretoria

URL: http://hdl.handle.net/2263/45235

► A wealth of studies indicates that good corporate governance has a positive impact on company performance. However, it is not always understood how this positive… (more)

▼ A wealth of studies indicates that good corporate governance has a positive impact on company performance. However, it is not always understood how this positive relationship is achieved. In firms where shareholders and management are misaligned and agency costs are high, cash and cash equivalents can be used in ways that lead to poor company performance and to the destruction of shareholder value. In addition to this problem, very few studies on corporate governance focus on emerging markets: “most studies of corporate governance focus on one or a few wealthy economies” (La Porta, Lopez-De-Silanes, Shleifer & Vishny, 1998, p.1117). Therefore, the focus of this study was to address these two main issues. The author of this report set out to understand the impact of corporate governance on corporate cash holdings by focusing on emerging markets. This was first done by reviewing the extensive literature on agency theory, firm-level corporate governance, cash holdings and the three hypotheses for reasons why firms hold cash. Firm-level corporate governance, corporate cash holdings and total assets data was collected for 620 firms in 17 emerging market economies using Thomson Reuters DataStream for the period 2009 to 2012. The data was then used to determine whether firm-level corporate governance, board characteristics, shareholder rights and vision and strategy are associated with corporate cash holdings. The study found that for the selected sample, firm-level corporate governance is negatively correlated to corporate cash holdings in emerging markets. This implies that the flexibility hypothesis is the dominant reason why firms hold cash in emerging markets. Emerging market firms tend to hoard cash because it provides the flexibility for these firms to take advantage of profitable opportunities as they present themselves. This outcome is contrary to the results obtained in prior studies done on firms in developed economies: these firms tend to spend cash quickly on acquisitions and capital projects (spending hypothesis) or they keep cash to avoid under-investing in case they cannot access external credit lines.(shareholder power hypothesis). Advisors/Committee Members: Chiba, Manoj (advisor).

Subjects/Keywords: UCTD; Corporate governance; Quantitative research

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Meloa, T. (2014). The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets. (Masters Thesis). University of Pretoria. Retrieved from http://hdl.handle.net/2263/45235

Chicago Manual of Style (16^th Edition):

Meloa, Tebogo. “The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets.” 2014. Masters Thesis, University of Pretoria. Accessed April 21, 2021. http://hdl.handle.net/2263/45235.

MLA Handbook (7^th Edition):

Meloa, Tebogo. “The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets.” 2014. Web. 21 Apr 2021.

Vancouver:

Meloa T. The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets. [Internet] [Masters thesis]. University of Pretoria; 2014. [cited 2021 Apr 21]. Available from: http://hdl.handle.net/2263/45235.

Council of Science Editors:

Meloa T. The association between firm-level corporate governance and corporate cash holdings: evidence from some emerging markets. [Masters Thesis]. University of Pretoria; 2014. Available from: http://hdl.handle.net/2263/45235

University of Nairobi

29. Ivara, J. Quantitative studies in grain amaranth populations .

Degree: 1988, University of Nairobi

URL: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24551

► Twenty-two grain amaranth populations were subjected to comparative evaluation for the number of days to flowering, the number of leaves on the main stem, the… (more)

▼ Twenty-two grain amaranth populations were subjected to comparative evaluation for the number of days to flowering, the number of leaves on the main stem, the number of leaves on the main branches, leaf length, leaf width, the number of days to maturity, plant height, plant weight, seed yield and harvest index in a randomised block design during the short rains of 1986 and long rains of 1987 at Kabete. The populations were Jumla, 125A, 1024, 718, UNK47 , UNK44 , 723, 674, 1023, 1008, 51, 84, 862, and 812 (all Amaranthus hypochondriacus); 1011, 434, UC87, and UC100 A. cruentus) 1113A and 982 (A. caudatus)f 1004 and 386 CA. hybridus). The results indicated that A. cruentus gave the highest means for the number of leaves on the main stem, leaf length, leaf width, plant height, plant weight and seed yield. A. hybridus gave the highest means for harvest index and the lowest means for the number of days to flowering, and the number of days to maturity, while A.caudatus gave the highest mean for the number of leaves on the main branches. Six of the above populations, namely, Jumla, 1023, 434, 1011, 982 and 1113A were investigated for within population variation for the above traits by planting eight Sl families from each population in a three-replicate compact family block design at Kabete in 1987. The amount of variability inherent within each of the six populations varied for the various traits. Population 1011 was the most heterogenous population as it showed significant variation among the families for all the traits except the number of days to flowering. Population 434 was the least variable population as it showed significant variation among its families for leaf length only. Population Jumla had significant variation for all the other traits except plant weight, the number of days to maturity and the number of leaves on the main stem. Population 1023 showed significant variability for the number of days to flowering, the number of days to maturity, leaf width, plant height and plant weight. Population 982 showed significant variation for the number of leaves on the main stem, the number of leaves on the main branches, leaf length, leaf width and plant height. Population 1113A showed significant variation for only four traits, namely, the number of days to flowering, the number of leaves on the main stem, plant height and seed yield. The variability within the populations was reflected in the values of broad sense heritability and selection response estimates which were estimated for each population separately. Traits like the number of leaves on the main stem, leaf length, leaf width, and plant height had high heritability estimates in population 1011. Likewise high expected selection response estimates were obtained for seed yield in populations Jumla, and 1113A, and the number of days to flowering in populations 1023 and 1113A. The data from the six populations were subjected to phenotypic, correlation and path-coefficient analyses to help identify the best metric traits that can be used as seed…

Subjects/Keywords: Quantitative studies

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ivara, J. (1988). Quantitative studies in grain amaranth populations . (Thesis). University of Nairobi. Retrieved from http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24551

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ivara, J. “Quantitative studies in grain amaranth populations .” 1988. Thesis, University of Nairobi. Accessed April 21, 2021. http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24551.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ivara, J. “Quantitative studies in grain amaranth populations .” 1988. Web. 21 Apr 2021.

Vancouver:

Ivara J. Quantitative studies in grain amaranth populations . [Internet] [Thesis]. University of Nairobi; 1988. [cited 2021 Apr 21]. Available from: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24551.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ivara J. Quantitative studies in grain amaranth populations . [Thesis]. University of Nairobi; 1988. Available from: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24551

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Nairobi

30. Ayiecho, P O. Quantitative studies in two grain amaranth populations using two selection methods .

Degree: 2013, University of Nairobi

URL: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24803

► A population of Amaranthus cruentus (UC87) and another of hypochondriacus (UC99) were subjected to Sl (selfed) family analysis of genetic variation for plant height, plant… (more)

▼ A population of Amaranthus cruentus (UC87) and another of hypochondriacus (UC99) were subjected to Sl (selfed) family analysis of genetic variation for plant height, plant weight, head length, head weight, threshing percentage, seed yield:height ratio, days to flowering, 500 seed weight, harvest index and seed yield per plant during the summer of 1982. Mass and recurrent Sl selections were initiated on the two populations for yield:height ratio and harvest index. These selections were advanced to second generation by mass selection in the summer of 1983. The Sl selection was also done for plant weight in UC87 and days to flowering in UC99. All generations of these selection experiments were evaluated together during the summer of 1984. Population UC87 had significant variation for threshing percentage, 500 seed weight and harvest index as indicated by Sl family analysis. High direct and indirect selection gains indicated presence of additive and additive x additive effects. This was confirmed for harvest index by component variance estimates. There were signs of overdominance in Sl selections. Population UC99 had significant genotypic variation for all traits except plant weight, head length and head weight. High direct and correlated selection gains indicated high additive and additive x additive effects. This was also confirmed by the genetic component estimates for yield:height ratio and harvest index. Realized gains from mass selection were higher than their expected values and the gains from Sl selection. Gains from the second cycle mass selection were lower than gains from the first cycle mass selection. These observations were attributed to the heterogeneity of UC99, which most likely involved competition, natural selection and higher homozygosity levels. In both populations mass selection was more efficient than S1 selection. This suggested a greater role of additive than the dominance component of variation. Based on correlation coefficients and multiple stepwise regression, the best yield predictors were plant height, head weight, threshing percentage and yield:height ratio. Harvest index was an important predictor for the yield of UC99 original population in 1984 only. Yield:height ratio was the most consistent predictor; the path-coefficient analyses indicated that most other variables influenced yield through yield:height ratio. Head weight was also an important indirect path for some predictors.

Subjects/Keywords: Quantitative study; Two grain amaranth

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ayiecho, P. O. (2013). Quantitative studies in two grain amaranth populations using two selection methods . (Thesis). University of Nairobi. Retrieved from http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24803

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ayiecho, P O. “Quantitative studies in two grain amaranth populations using two selection methods .” 2013. Thesis, University of Nairobi. Accessed April 21, 2021. http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24803.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ayiecho, P O. “Quantitative studies in two grain amaranth populations using two selection methods .” 2013. Web. 21 Apr 2021.

Vancouver:

Ayiecho PO. Quantitative studies in two grain amaranth populations using two selection methods . [Internet] [Thesis]. University of Nairobi; 2013. [cited 2021 Apr 21]. Available from: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24803.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ayiecho PO. Quantitative studies in two grain amaranth populations using two selection methods . [Thesis]. University of Nairobi; 2013. Available from: http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24803

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Open Access Theses and Dissertations