subject:( Pregnancy)

Rutgers University

1. Moscovitz, Jamie Esther, 1989-. Enterohepatic nuclear receptor signaling during pregnancy.

Degree: PhD, Toxicology, 2016, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/

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Physiological adaptations to the intestine-liver axis during pregnancy alter the disposition of xenobiotics and endobiotics. As a result, some pregnant women experience decreased efficacy or… (more)

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Physiological adaptations to the intestine-liver axis during pregnancy alter the disposition of xenobiotics and endobiotics. As a result, some pregnant women experience decreased efficacy or adverse reactions to prescription medications (xenobiotic effect), while others may become susceptible to cholestatic liver disease due to enhanced bile acid levels (endobiotic effect). The purpose of this dissertation research was to characterize molecular adaptations in enterohepatic nuclear receptor signaling and downstream bile acid and xenobiotic disposition pathways that can occur during late pregnancy. In ilea collected from mice in late gestation, an overall down-regulation of Farnesoid X Receptor (Fxr/Nr1h4) and Pregnane X Receptor (Pxr/Nr1i2) signaling, including target enzyme and transporter expression, was observed. To explore potential mechanisms, the ability of candidate sex hormones to alter the expression of enzyme and transport genes regulated by FXR and PXR were studied in human intestinal cells. In vitro studies suggest a prominent role for progesterone-mediated interference with PXR signaling in the intestine during pregnancy that could contribute to altered xenobiotic transport. Further assessment of the ability of activated Fxr to modulate hepatic and intestinal regulation of bile acid synthesis and transport pathways during pregnancy was investigated in mice. Treatment of pregnant mice with the specific Fxr agonist GW4064 restored the expression of bile acid synthesis enzymes and transporters towards levels typically observed in virgin mice. This study provides the molecular basis for a novel approach to restore bile acid homeostasis in patients with maternal cholestasis. Finally, loss-of-function studies in pregnant Fxr-null mice revealed that deficiency in the Fxr gene prevents pregnancy-mediated repression of key bile acid regulatory factors and transporters, largely in the intestines. Taken together, these data advance our understanding of alterations in chemical disposition during pregnancy, and the overall â€œprocholestaticâ€ state of pregnancy that sensitizes women to acquiring liver disease.

Advisors/Committee Members: Aleksunes, Lauren M (chair), Guo, Grace L (internal member), Roepke, Troy (internal member), Gallo, Michael (internal member), Thompson, Kary (outside member).

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Moscovitz, Jamie Esther, 1. (2016). Enterohepatic nuclear receptor signaling during pregnancy. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/51372/

Chicago Manual of Style (16^th Edition):

Moscovitz, Jamie Esther, 1989-. “Enterohepatic nuclear receptor signaling during pregnancy.” 2016. Doctoral Dissertation, Rutgers University. Accessed February 26, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/51372/.

MLA Handbook (7^th Edition):

Moscovitz, Jamie Esther, 1989-. “Enterohepatic nuclear receptor signaling during pregnancy.” 2016. Web. 26 Feb 2021.

Vancouver:

Moscovitz, Jamie Esther 1. Enterohepatic nuclear receptor signaling during pregnancy. [Internet] [Doctoral dissertation]. Rutgers University; 2016. [cited 2021 Feb 26]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/.

Council of Science Editors:

Moscovitz, Jamie Esther 1. Enterohepatic nuclear receptor signaling during pregnancy. [Doctoral Dissertation]. Rutgers University; 2016. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/

Rutgers University

2. Parobchak, Nataliya, 1987-. Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.

Degree: MS, Toxicology, 2020, Rutgers University

URL: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/

► The goal of this study was to characterize the expression and signaling of uterine GPR83 in vivo in the nonpregnant and pregnant mouse and in vitro in human endometrial… (more)

▼ The goal of this study was to characterize the expression and signaling of uterine GPR83 in vivo in the nonpregnant and pregnant mouse and in vitro in human endometrial and non-endometrial cells. Expression of uterine Gpr83 was determined by quantitative polymerase chain reaction throughout the estrous cycle and during early pregnancy in ovarian-stimulated and non−ovarian-stimulated mice and pregnant and pseudopregnant mice. Expression was also determined in ovariectomized mice after the administration of oil, E2, P4, or E2 + P4 and in stromal cells following 6 days of in vitro decidualization. GPR83 signaling was studied in human endometrial and embryonic kidney cell lines. Cells were treated with PEN, a GPR83 ligand, and PEN-induced extracellular signal-regulated kinase (ERK) phosphorylation was assayed under conditions that blocked Gαq/11 and/or β-arrestin signaling. Results show that uterine Gpr83 is expressed throughout the estrous cycle and during early pregnancy; expression increases dramatically at the time of uterine receptivity, embryo implantation, and stromal cell decidualization. In the ovariectomized mouse, hormone add-back reveals that Gpr83 expression is highly responsive to the combined treatment of E2 and P4, and studies in the ovarian-stimulated mouse show that expression is also very sensitive to changes in E2 and P4 and is therefore tightly regulated by E2 and P4. At the implantation site, expression is elevated up to D6 of pregnancy and then declines rapidly on D7 and D8, suggesting that if there is any involvement in decidualization, it is likely associated with primary but not secondary stromal cell decidualization. This premise was supported by the observation that stromal cell decidualization in vitro progresses with a decline in Gpr83 expression. In ERα/PR-expressing endometrial Ishikawa cells, GPR83 mediates PEN signals in a Gαq/11-dependent manner, and studies conducted in HEK 293 cells lacking β-arrestin revealed that GPR83 also signals via a β-arrestin−dependent manner. When signaling by either one or both pathways is downregulated, cells exhibit a major reduction in responsiveness to PEN treatment, demonstrating that signaling by both pathways is significant. Based on our findings, we hypothesize that PEN/GPR83 signaling regulates uterine receptivity, embryo implantation, and primary stromal cell decidualization by coupling to Gαq/11- and β-arrestin−dependent pathways. Advisors/Committee Members: Babwah, Andy (chair), Aleksunes, Lauren (internal member), Reuhl, Kenneth (internal member), School of Graduate Studies.

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Parobchak, Nataliya, 1. (2020). Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/64942/

Chicago Manual of Style (16^th Edition):

Parobchak, Nataliya, 1987-. “Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.” 2020. Masters Thesis, Rutgers University. Accessed February 26, 2021. https://rucore.libraries.rutgers.edu/rutgers-lib/64942/.

MLA Handbook (7^th Edition):

Parobchak, Nataliya, 1987-. “Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.” 2020. Web. 26 Feb 2021.

Vancouver:

Parobchak, Nataliya 1. Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. [Internet] [Masters thesis]. Rutgers University; 2020. [cited 2021 Feb 26]. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/.

Council of Science Editors:

Parobchak, Nataliya 1. Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. [Masters Thesis]. Rutgers University; 2020. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/

University of Auckland

3. Atkinson, Kelly Rene LeFevre. Proteomic biomarker discovery for preeclampsia.

Degree: 2008, University of Auckland

URL: http://hdl.handle.net/2292/2565

► Preeclampsia is a serious multisystem complication of late pregnancy with adverse effects for mothers and babies. Currently this disorder is diagnosed from clinical observations occurring… (more)

▼ Preeclampsia is a serious multisystem complication of late pregnancy with adverse effects for mothers and babies. Currently this disorder is diagnosed from clinical observations occurring late in the disease process. Unknown factors in the maternal circulation, possibly released by the preeclamptic placenta, have been linked to the pathophysiological changes characteristic of the disorder. The research in this thesis used proteomic techniques to identify putative preeclampsia biomarkers from two sources: secreted from a placental cell line undergoing differentiation, and directly sampled from the serum and plasma of women with late-onset preeclampsia. The first part of this research examined the secreted proteome of a placental choriocarcinoma cell line (BeWo) undergoing forskolin-mediated differentiation. Development of serum-free culture techniques enabled analysis of these secreted proteins by two-dimensional gel electrophoresis (2DE). Statistical testing revealed the significant involvement of seven spots during this differentiation model, with VE-cadherin and matrix metalloproteinase 2 among the proteins identified. In the second part of this research, maternal serum and plasma proteins were compared from women with preeclampsia and healthy pregnant women. Serum samples were analyzed using 2DE, and plasma was subjected to difference gel electrophoresis (DIGE). Bioinformatic analysis of both datasets identified multiple spot clusters able to classify samples according to disease state. Five of these serum proteins were differentially regulated in preeclampsia, including two isoforms of apolipoprotein E whose isoform-specific expression was confirmed using western blots. Analysis of plasma from preeclamptic women identified six proteins, again including apolipoprotein E. Proteins from both studies are linked to preeclampsia pathophysiology through lipid transport, complement, and retinol transport systems. The culture methods and secreted proteomic techniques developed in this work have uncovered proteins in a placental cell line and maternal serum and plasma that are associated with preeclampsia. These methods can be extended to any system where secreted proteins are of interest. The differentially regulated proteins found in this study provide an important first step towards developing effective biomarkers for diagnosing and/or predicting preeclampsia. Advisors/Committee Members: Garth Cooper, Robyn North.

Subjects/Keywords: proteomics; pregnancy

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APA (6^th Edition):

Atkinson, K. R. L. (2008). Proteomic biomarker discovery for preeclampsia. (Doctoral Dissertation). University of Auckland. Retrieved from http://hdl.handle.net/2292/2565

Chicago Manual of Style (16^th Edition):

Atkinson, Kelly Rene LeFevre. “Proteomic biomarker discovery for preeclampsia.” 2008. Doctoral Dissertation, University of Auckland. Accessed February 26, 2021. http://hdl.handle.net/2292/2565.

MLA Handbook (7^th Edition):

Atkinson, Kelly Rene LeFevre. “Proteomic biomarker discovery for preeclampsia.” 2008. Web. 26 Feb 2021.

Vancouver:

Atkinson KRL. Proteomic biomarker discovery for preeclampsia. [Internet] [Doctoral dissertation]. University of Auckland; 2008. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2292/2565.

Council of Science Editors:

Atkinson KRL. Proteomic biomarker discovery for preeclampsia. [Doctoral Dissertation]. University of Auckland; 2008. Available from: http://hdl.handle.net/2292/2565

University of Namibia

4. Mungoba, TN. Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati .

Degree: 2015, University of Namibia

URL: http://hdl.handle.net/11070/1697

► Globally an estimate of 350 000 to 500 000 women die annually from preventable causes related to pregnancy and childbirth. An adverse pregnancy outcome is… (more)

▼ Globally an estimate of 350 000 to 500 000 women die annually from preventable causes related to pregnancy and childbirth. An adverse pregnancy outcome is an incident which reduces the chance of having a healthy baby, two or more 1st trimester miscarriage. Previous studies reveal that adverse pregnancy outcomes were threatening the lives of both the mother and child. The burden of adverse pregnancy outcomes among women who deliver at Intermediate Hospital Oshakati is a major public health concern. It has frequently been reported in the local media that adverse pregnancy outcomes among women in Namibia is a common occurrence. The objective of this study was to determine and describe the factors associated with adverse pregnancy outcomes and compare the adverse pregnancy outcomes between teenage and older mothers. A quantitative analytical, contextual, cross-sectional study was conducted. Pregnant women who delivered at Intermediate Hospital Oshakati from July to September 2015 were interviewed, using a structured questionnaire. Information on demographic, potential risk factors and adverse pregnancy outcomes were collected and analyzed using Epi info. We enrolled a total of 306 pregnant women of whom 50% (n=153) were teenage and 50% (n=153) were older mothers. A total of n=164 (53.60%) had adverse pregnancy outcomes, whereas n=142 (46.40%) did not have adverse pregnancy outcomes. Significant bivariate results included regions (OR 0.33, 95%CI: 0.12-0.94, p=0.0314), residential areas (OR=0.43, 95%CI: 0.25-0.74, p=0.0021), gestational weeks (OR 0.75, 95%CI: 0.65-0.88, p=0.0004), BMI (OR 0.56, 95%CI: 0.32-0.98, p=0.0430), haemoglobin (OR 0.33, 95%CI: 0.16-0.69, p=0.0029), and blood pressure (OR 9.56, 95%CI: 1.19-77.5, p=0.0334). The adverse pregnancy outcomes are a real public health issue, which need to be addressed. It is recommended that each district hospitals have specialists in obstetric care and advanced midwifery, and to sensitize all pregnant women about the adverse pregnancy outcomes and how to prevent it.

Subjects/Keywords: Adverse pregnancy

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APA (6^th Edition):

Mungoba, T. (2015). Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati . (Thesis). University of Namibia. Retrieved from http://hdl.handle.net/11070/1697

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Mungoba, TN. “Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati .” 2015. Thesis, University of Namibia. Accessed February 26, 2021. http://hdl.handle.net/11070/1697.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Mungoba, TN. “Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati .” 2015. Web. 26 Feb 2021.

Vancouver:

Mungoba T. Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati . [Internet] [Thesis]. University of Namibia; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/11070/1697.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Mungoba T. Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati . [Thesis]. University of Namibia; 2015. Available from: http://hdl.handle.net/11070/1697

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

5. Nusraat, Gangat. Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka .

Degree: 2016, University of Zambia

URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796

► Background: The latent phase of labour is poorly understood and duration of this phase is significantly difficult to measure. Prolonged latent phase (PLP) accounts for… (more)

Subjects/Keywords: pregnancy complications.

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APA (6^th Edition):

Nusraat, G. (2016). Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka . (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4796

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Nusraat, Gangat. “Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka .” 2016. Thesis, University of Zambia. Accessed February 26, 2021. http://dspace.unza.zm:8080/xmlui/handle/123456789/4796.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Nusraat, Gangat. “Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka .” 2016. Web. 26 Feb 2021.

Vancouver:

Nusraat G. Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka . [Internet] [Thesis]. University of Zambia; 2016. [cited 2021 Feb 26]. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nusraat G. Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka . [Thesis]. University of Zambia; 2016. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University

6. Redhead, MacKenzie. The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development .

Degree: Anatomy and Cell Biology, 2015, Queens University

URL: http://hdl.handle.net/1974/13694

► Uterine natural killer (uNK) cells are the most abundant lymphocyte in early human and mouse decidua. UNK cell functions have been deduced by histopathologic comparisons… (more)

▼ Uterine natural killer (uNK) cells are the most abundant lymphocyte in early human and mouse decidua. UNK cell functions have been deduced by histopathologic comparisons of implantation sites between alymphoid (NK-T-B-), NK cell reconstituted alymphoid (NK+T-B-) and normal NK+T+B+ mice. Circulating (c)NK cells are reported to be absent from C57BL/6 mice genetically ablated for the transcription factor Nfil3 (cNK-T+B+) and these mice experience midgestation Th17 cell-mediated fetal loss when mated by BALB/c males. Recently, tissue resident subsets of NK cells have been described in this mouse. A histological time-course examination of syngeneic Nfil3-/- male x Nfil3-/- female and allogeneic BALB/c-Tg(UBC-GFP)30Scha/J male x Nfil3-/- female pregnancy (gestation day; GD 6.5-15.5) was performed to determine the consequences of a maternal cNK-T+B+ phenotype on pregnancy with an Nfil3-/- or Nfil3+/- conceptus. Whole mount immunofluorescence (WM-IF) was used as an additional technique to provide greater insights at midgestation. Nfil3 is a pleiotrophic factor; to examine Nfil3-dependent uNK cell-specific effects, pregnancies in Nfil3-/- bone marrow engrafted alymphoid mice (BME) were studied. UNK cells were less frequent in Nfil3-/- pregnancies and viability of Nfil3-/- implantation sites (IS) did not differ from wild type (WT) matings. Early gestation pathologies included impaired antimesometrial decidualization (AMD) and delays in lumen closure and embryo development (ED). WM examination revealed an enrichment of CD45+CD11c+ cells at GD 8.5 in Nfil3-/- IS compared to WT. Mid-late gestation placental development, including labyrinth vascular space area and interhemal membrane width, deviated significantly less from WT in allogeneic compared to syngeneic matings. BME and alymphoid placental development was similar to WT. Spiral artery (SA) remodeling did not occur in any experimental mating. Results of the present investigation suggest Nfil3-independent uNK cells do not promote AMD or GD 8.5 ED and cannot remodel SAs. Nfil3 plays a role in placental tissue layer (specifically labyrinth) development possibly through trophoblast-dependent mechanisms. The absence of Nfil3 may promote recruitment or differentiation of CD45+CD11c+ cells in the early gestation implantation site. Although not an effective model for studying NK-T+B+ pregnancy, the Nfil3-/- mouse deepens the understanding of innate lymphoid cells and their respective subsets.

Subjects/Keywords: Pregnancy ; NFIL3

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APA (6^th Edition):

Redhead, M. (2015). The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development . (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/13694

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Redhead, MacKenzie. “The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development .” 2015. Thesis, Queens University. Accessed February 26, 2021. http://hdl.handle.net/1974/13694.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Redhead, MacKenzie. “The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development .” 2015. Web. 26 Feb 2021.

Vancouver:

Redhead M. The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development . [Internet] [Thesis]. Queens University; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1974/13694.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Redhead M. The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development . [Thesis]. Queens University; 2015. Available from: http://hdl.handle.net/1974/13694

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Nairobi

7. Kato, Dismas Kituyi. Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County .

Degree: 2015, University of Nairobi

URL: http://hdl.handle.net/11295/90755

► Retention of students from the beginning of their education to completion at any level is the hallmark and the ultimate goal of any education system… (more)

▼ Retention of students from the beginning of their education to completion at any level is the hallmark and the ultimate goal of any education system in any country. Compared to boys, girls face numerous hurdles in their pursuit of education that causes unanticipated school interruptions and the likely eventuality of school dropout; a phenomenon that affects equitable human capital formation. Specific to the girl child, is the menace of teenage pregnancy and the associated secondary school dropout that this study sought to address. The study was guided by human capital theory. The specific objectives were: to establish the extent to which individual factors influence teenage pregnancy in public day secondary schools in Kimilili Sub-County, to examine the extent to which home based factors influence teenage pregnancy in public day secondary schools in Kimilili Sub-County, to determine the extent to which school factors influence teenage pregnancy in public day secondary schools in Kimilili Sub-County and to assess the extent to which teenage pregnancy influence completion rate of girls in public day secondary schools Kimilili Sub-County. The study deployed descriptive survey research design. The accessible population was 300 form four girls, 18 Directors of Study and 1 D. o. E. Stratified random sampling was used to come up with 90 form four girls from 8 schools and 8 Directors of Study while census sampling was used to select the D.o.E. The study used questionnaires for students and Directors of Study and an interview schedule was administered on the Sub County D.o.E. Validity of the instruments was determined by the researcher who formulated items according to the research objectives. Experts from the Department of Educational Administration and Planning verified content validity. The instruments were piloted in two schools that were excluded in the actual study and test re-test method was used to calculate reliability. A reliability coefficient of 0.6 was attained and hence accepted as reliable. Data collected was analyzed using measures of central tendency. Results were then presented using tables. The study found out that individual sexual behaviour of students, lack of strict parental supervision and monitoring, home poverty, poor academic performance at school, and sexual harassment by both boys and teachers exposed girls to the problem of teenage pregnancy. The study also established that over 40% of the girls‟ dropout cases were due to teenage pregnancy over the four year cycle in day secondary schools in Kimilili Sub-County. The study recommended the creation of clear partnerships between public health facilities and schools to promote effective utilization of YFRHS, sensitization of parents on their roles, monitoring of poor academic performers at school and legal prosecution of teachers found harassing school girls.

Subjects/Keywords: Teenage pregnancy

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APA (6^th Edition):

Kato, D. K. (2015). Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County . (Thesis). University of Nairobi. Retrieved from http://hdl.handle.net/11295/90755

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kato, Dismas Kituyi. “Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County .” 2015. Thesis, University of Nairobi. Accessed February 26, 2021. http://hdl.handle.net/11295/90755.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kato, Dismas Kituyi. “Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County .” 2015. Web. 26 Feb 2021.

Vancouver:

Kato DK. Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County . [Internet] [Thesis]. University of Nairobi; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/11295/90755.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kato DK. Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County . [Thesis]. University of Nairobi; 2015. Available from: http://hdl.handle.net/11295/90755

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

8. Chisha, Percival Sume. Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka .

Degree: 2016, University of Zambia

URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701

► Background: Ectopic pregnancy is defined as a pregnancy outside the uterine cavity and is a life-threatening emergency in the field of obstetrics and gynaecology. It… (more)

▼ Background: Ectopic pregnancy is defined as a pregnancy outside the uterine cavity and is a life-threatening emergency in the field of obstetrics and gynaecology. It is a most common cause of maternal morbidity and mortality in the first trimester of pregnancy. In resource-constrained settings, where trained specialists are limited in number and geographic location, outcomes are worse. Diagnosis is frequently missed, partly because the patient may not be aware that she is pregnant. However, timely diagnosis accompanied by appropriate management of ectopic pregnancy can alter the clinical course from death to life. The study aims to determine the epidemiology of ectopic pregnancies at University Teaching Hospital (UTH). Methods: A cross sectional study conducted between May, 2014 to November, 2014 in the Department of Obstetrics and Gynaecology at the University Teaching Hospital, Lusaka, Zambia. Women treated for ectopic pregnancies were recruited from the gynaecology ward, interviewed by research assistants and data abstracted from their medical files. Results: A total of 90 women with ectopic pregnancies were enrolled representing 0.5% of early and late pregnancy admissions (total 19,600 pregnant women reviewed between May 2014 –November, 2014). Over 70% were from high residential areas, 52% had at least secondary education, and 81.1% were married or co-habiting. Although 27.8% were HIV positive, 37.8% did not have a known status. Almost half (46.6%) were in their first or second pregnancy. Though 10% were in the second trimester (13-19weeks) gestation, most (67.8%) were below 12 weeks and in 22% the gestation was not known. The commonest risk factors were: more than one sexual partner ever (55.6%) with 10% ever treated for a sexually transmitted disease. The commonest symptoms were lower abdominal pain (97.8%) and amaenorrhea (83.3%). Dizziness was reported in 48.9%. About a quarter (24.4%) were considered in shock on admission and most had abdominal tenderness (86.7%). Where an ultrasound was done (n=57, 63.3%) this was helpful in 86% of cases (n=49). Haemoperitnem was reported in 59.6%. In 65 cases (72.2%) either paracentesis or culdocentesis was done and was positive for blood in 49 (75.4%) of cases. Apart from only one case treated with methotrexate, all other had a laparotomy and 70% were found ruptured. The commonest sites for the ectopic were infundibulum (33.3%) and ampulla (28.9%). Salpingectomy was the commonest procedure (84.4%). Over half (54.3%) had blood loss greater than 500mls. And 44 (48.9%) were transfused. In 34 cases of those transfused, one or two units were transfused. Four patients (4.4%) were recovered in a high dependency unit – the rest in an ordinary ward. One patient died (case fatality of 1.1%). Conclusion: The series at UTH showed that ectopic pregnancy had a low prevalence and had a risk factor profile and clinical presentation like that described elsewhere in the region. Most cases presented with a ruptured ectopic requiring blood transfusion.…

Subjects/Keywords: ectopic pregnancy.

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APA (6^th Edition):

Chisha, P. S. (2016). Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka . (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4701

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chisha, Percival Sume. “Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka .” 2016. Thesis, University of Zambia. Accessed February 26, 2021. http://dspace.unza.zm:8080/xmlui/handle/123456789/4701.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chisha, Percival Sume. “Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka .” 2016. Web. 26 Feb 2021.

Vancouver:

Chisha PS. Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka . [Internet] [Thesis]. University of Zambia; 2016. [cited 2021 Feb 26]. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chisha PS. Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka . [Thesis]. University of Zambia; 2016. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

North-West University

9. Gaoaketse, Violet Keitumetsi. Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse .

Degree: 2013, North-West University

URL: http://hdl.handle.net/10394/14412

► Learner pregnancy is regarded as a major concern and a serious threat to gender parity in education. Addressing learner pregnancy is not a challenge facing… (more)

▼ Learner pregnancy is regarded as a major concern and a serious threat to gender parity in education. Addressing learner pregnancy is not a challenge facing only Department of Education, it is a battle that requires the active involvement of all stakeholders that is educators, Non -governmental organisation, Department of Education, Health and Social Development. The rate of learner pregnancy in public schools, prompted the Department of Education to release the policy of Learner Pregnancy Policy which ensures the rights of pregnant learners to continue with schools. The policy is based on prevention and management. This research study investigate how schools implement learner pregnancy policy. The objectives of the study are: • To investigate how schools encourage the prevention strategies of learner pregnancy policy; • To investigate how schools manage learner pregnancy; • To identify how Department of Education are involved in monitoring of the schools in implementing the pregnant learner policy. The study was conducted in four targeted high schools in the Lichtenburg area A qualitative approach and quantitative approach was used. Questionnaires and interviews were used as instruments. A purposeful sampling of 100 educators and 10 managers was selected. Statistical Package for Social Sciences was used for data analysis. The Findings of the study revealed that schools are not doing enough to provide learners with prevention strategies of learner pregnancy; Even though the policy encourages managers and educators to support learners who are pregnant, educators and managers still need to encourage pregnant learners to continue with their education when they are pregnant in line with the policy. Department of Education does not monitor and evaluate the effectiveness of the policy regularly in schools. Recommendation of the study revealed that: Learners must be engaged in extra mural activities to keep them busy, Educators and managers must help, support and encourage pregnant learners to continue with their education and that the Provincial Department of Education must appoint a person at the department to monitor the effectiveness of the policy in schools, to visits schools regularly and to ensure their compliance.

Subjects/Keywords: Teenage pregnancy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gaoaketse, V. K. (2013). Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse . (Thesis). North-West University. Retrieved from http://hdl.handle.net/10394/14412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gaoaketse, Violet Keitumetsi. “Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse .” 2013. Thesis, North-West University. Accessed February 26, 2021. http://hdl.handle.net/10394/14412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gaoaketse, Violet Keitumetsi. “Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse .” 2013. Web. 26 Feb 2021.

Vancouver:

Gaoaketse VK. Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse . [Internet] [Thesis]. North-West University; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10394/14412.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gaoaketse VK. Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse . [Thesis]. North-West University; 2013. Available from: http://hdl.handle.net/10394/14412

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape

10. Johnstone, Muriel. Teenage mothers’ reflections of their unintended, repeat pregnancies .

Degree: 2013, University of the Western Cape

URL: http://hdl.handle.net/11394/3574

► Globally, teenage pregnancy remains a disturbing phenomenon which impacts on the lives of teenagers, their families and society as a whole. Numerous attempts at addressing… (more)

▼ Globally, teenage pregnancy remains a disturbing phenomenon which impacts on the lives of teenagers, their families and society as a whole. Numerous attempts at addressing the problem have seen a decline in fertility rates but agreement still exists that the incidence of young girls bearing children is unacceptably high. Studies conducted over the years have emphasised both the causes and consequences of teenage births. Many studies too have explored the benefits of preventative strategies. Yet, despite all this, teenage pregnancy remains a cause for concern with many teenage girls remaining sexually active after a first pregnancy, and exposing themselves to subsequent pregnancies and births. This study was focused on teenage girls who had experienced unintended repeat pregnancies. Through the research a deeper understanding of the meanings that female teenagers ascribe to repeat pregnancies, were sought. A sample group of teenage mothers were allowed to take a step back from their experience of the repeat pregnancy; to think deeply about the experience, and to reflect on what they had learnt and how it has impacted on their current lives. The researcher employed a qualitative approach with a descriptive, explorative design in order to obtain a rich description of the experiences of teenage mothers who have been through a repeat pregnancy. The goal of the study was to explore and describe the reflections of these teenage mothers who had experienced unintended, repeat pregnancies. Data was obtained through semi-structured individual interviews where an interview guide was used. The data was analysed according to the steps outlined by Creswell (2009). Findings were noted and recommendations made. These recommendations are designed for role-players involved with teenagers and youth in general. Emphasis was placed on recommendations to professionals, like educators, healthcare workers and social workers who are at the coalface of dealing with teenagers who engage in sexual activity. Finally, recommendations for further research were made. Advisors/Committee Members: Jager, M. de (advisor).

Subjects/Keywords: Reflections; Teenager/Adolescent; Pregnancy; Teenage/Adolescent pregnancy; Repeat pregnancy; Unintended pregnancy

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APA (6^th Edition):

Johnstone, M. (2013). Teenage mothers’ reflections of their unintended, repeat pregnancies . (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/3574

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Johnstone, Muriel. “Teenage mothers’ reflections of their unintended, repeat pregnancies .” 2013. Thesis, University of the Western Cape. Accessed February 26, 2021. http://hdl.handle.net/11394/3574.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Johnstone, Muriel. “Teenage mothers’ reflections of their unintended, repeat pregnancies .” 2013. Web. 26 Feb 2021.

Vancouver:

Johnstone M. Teenage mothers’ reflections of their unintended, repeat pregnancies . [Internet] [Thesis]. University of the Western Cape; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/11394/3574.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Johnstone M. Teenage mothers’ reflections of their unintended, repeat pregnancies . [Thesis]. University of the Western Cape; 2013. Available from: http://hdl.handle.net/11394/3574

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University

11. Palmer, Helen Jean. Factors affecting hypertriglyceridemia during pregnancy.

Degree: MS, Department of Food Science and Human Nutrition, 1979, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:42319

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Palmer, H. J. (1979). Factors affecting hypertriglyceridemia during pregnancy. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:42319

Chicago Manual of Style (16^th Edition):

Palmer, Helen Jean. “Factors affecting hypertriglyceridemia during pregnancy.” 1979. Masters Thesis, Michigan State University. Accessed February 26, 2021. http://etd.lib.msu.edu/islandora/object/etd:42319.

MLA Handbook (7^th Edition):

Palmer, Helen Jean. “Factors affecting hypertriglyceridemia during pregnancy.” 1979. Web. 26 Feb 2021.

Vancouver:

Palmer HJ. Factors affecting hypertriglyceridemia during pregnancy. [Internet] [Masters thesis]. Michigan State University; 1979. [cited 2021 Feb 26]. Available from: http://etd.lib.msu.edu/islandora/object/etd:42319.

Council of Science Editors:

Palmer HJ. Factors affecting hypertriglyceridemia during pregnancy. [Masters Thesis]. Michigan State University; 1979. Available from: http://etd.lib.msu.edu/islandora/object/etd:42319

Addis Ababa University

12. Emshaw, Tirfe. Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.

Degree: 2019, Addis Ababa University

URL: http://10.6.20.92/handle/123456789/20909

► Background: Globally every day 830 women die from preventable causes related to pregnancy and childbirth and 99% of maternal deaths occur in developing countries. Young… (more)

▼ Background: Globally every day 830 women die from preventable causes related to pregnancy and childbirth and 99% of maternal deaths occur in developing countries. Young people and adolescents face higher risk of complication. Unintended pregnancy among young people increases risk of maternal morbidity and mortality. Objectives: The objectives of this study are to estimate the prevalence of unintended pregnancy among youth in Ethiopia and to explore the factors associated with the unintended pregnancy. Methods: We employed mixed methods. The quantitative part applied cross sectional study design using data from Ethiopian Demographic and Health Survey (EDHS) 2016. The dataset was accessed online www.measuredhs.com. The qualitative method applied in- depth interview of purposively selected 15-24 years old female who visited health facilities for antenatal or abortion care service. Quantitative data was analyzed using STATA version 14 software. Descriptive and binary logistical regression analysis techniques were used to estimate the prevalence unintended pregnancy and identify factors associated with unintended pregnancy. Qualitative data was analyzed by open code version 4.02 using content analysis method. Result: Four hundred youths (6.5%) were found to be pregnant from a total of 6,143 (weighted) youths who participated in the 2016 EDHS. Among the pregnant youths 141(35.3%) had no education, 197(49.3%) attended primary school, 372 (93%) were married, 235(58.8%) were unemployed, and 343(85.7%) live in rural area. The prevalence of unintended pregnancy among pregnant youth was 25%. In-depth interview data analysis showed contraceptive failure, not using any modern contraceptive, low risk prediction, lack of support by family, partner disagreement and desire to continue education were found to be the main reasons for having unintended pregnancy. Conclusion and Recommendation: The prevalence of unintended pregnancy among youth in Ethiopia is high. Effort should focus on empowering women to make them psychological and economic independent to enable them decide about their pregnancy. Changing the wrong belief and perception on modern contraception in the community is important to improve utilization of those methods by young women. Advisors/Committee Members: Assegid, Meselech(B.Sc., MPH) (advisor), Seifu, Abiy(B.Sc., MPH) (advisor).

Subjects/Keywords: Unintended pregnancy

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APA (6^th Edition):

Emshaw, T. (2019). Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019. (Thesis). Addis Ababa University. Retrieved from http://10.6.20.92/handle/123456789/20909

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Emshaw, Tirfe. “Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019. ” 2019. Thesis, Addis Ababa University. Accessed February 26, 2021. http://10.6.20.92/handle/123456789/20909.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Emshaw, Tirfe. “Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019. ” 2019. Web. 26 Feb 2021.

Vancouver:

Emshaw T. Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019. [Internet] [Thesis]. Addis Ababa University; 2019. [cited 2021 Feb 26]. Available from: http://10.6.20.92/handle/123456789/20909.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Emshaw T. Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019. [Thesis]. Addis Ababa University; 2019. Available from: http://10.6.20.92/handle/123456789/20909

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McGill University

13. Philip, Anie. Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.

Degree: PhD, Department of Physiology, 1986, McGill University

URL: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g

►

Sex hormone-binding globulin ( SHBG) is a plasma protein which binds testosterone and estradiol in vitro with high affinity and specificity. There is conflicting evidence… (more)

▼

Sex hormone-binding globulin ( SHBG) is a plasma protein which binds testosterone and estradiol in vitro with high affinity and specificity. There is conflicting evidence as to the role of SHBG in the transport of estradiol under in vive conditions. Studies describing the distribution of estradiol and testosterone into SHBG-bound, albumin-bound and unbound fractions were carried out using equilibrium dialysis of whole serum at 37°C under isosmotic conditions. The results showed that SHBG was an important binder of estradiol in both pregnant and non-pregnant women, but of minimal significance in men and in newborn infants. Testosterone was significantly bound to SHBG under all circumstances. In order to characterize previously unrecognized substances that may bind to SHBG in pregnancy, maternal serum was fractionated on Sephadex LH-20. A substantial part of the SHBG-bound material eluted as 4 major peaks which did not correspond to any of the steroids thought to bind to SHBG. Comparison of levels in maternal, fetal and placental compartments suggested that all 4 peaks were of placental origin. Three were identified as 5 a-pregnane-3, 20-dione, progesterone and 2-methoxyestrone on the basis of elution pattern on Sephadex LH-20, binding characteristics, high performance liquid chromatography, and gas chromatography-mass spectrometry. The fourth peak was identified as a 19-nor androgen, i.e. 17B-hydroxy-1, 5-estradiene-3-one, on the basis of similar kinds of evidence and in addition, solubility characteristics and ultra-violet absorption spectrum. Since its level fell in association with premature and term labour, its decrease may be involved in the initiation of labour.

La globuline liant les hormones sexuelles (Sex Hormone Binding Globulin, SHBG) est une protéine plasmatique qui se lie spécifiquement à la testostérone et a l'estradiol in vitro. Cette liaison est de haute affinité. Toutefois, le rôle de la SHBG dans le transport de l'estradiol in vivo est mal connu. Nous avons procédé à l'étude des fractions d'estradiol et de testostérone liées à la SHBG ou à l'albumine ou simplement libres en effectuant une dialyse a l'équilibre du sérum à 37°C en conditions isosmotiques. Les résultats ont démontré que la SHBG constitue un facteur important dans la liaison de l'estradiol sérique chez la femme gravide et non gravide. Toutefois, la liaison à l'estradiol s'est avérée minime chez l'homme et chez le nouveau-né. La testostérone était liée à la SHBG en quantité significative dans toutes les conditions que nous avons étudiées. Afin de procéder à la caractérisation de substances liées à la SHBG durant la grossesse et jusqu'à présent non identifiés, le sérum maternel a été fractionné sur Sephadex LH-20. Une proportion importante du matériel lie à la SHBG éluait en 4 principaux pies lesquels ne correspondaient à aucune des stéroïdes que l'on pense se lient à la SHBG. La comparaison des niveaux des quatres pies dans les compartiments maternel, fétal et placentaire suggérait que ces derniers étaient d'origine placentaire. Trois…

Advisors/Committee Members: Pearson, Beverley E..

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Philip, A. (1986). Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g

Chicago Manual of Style (16^th Edition):

Philip, Anie. “Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.” 1986. Doctoral Dissertation, McGill University. Accessed February 26, 2021. https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g.

MLA Handbook (7^th Edition):

Philip, Anie. “Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.” 1986. Web. 26 Feb 2021.

Vancouver:

Philip A. Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. [Internet] [Doctoral dissertation]. McGill University; 1986. [cited 2021 Feb 26]. Available from: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g.

Council of Science Editors:

Philip A. Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. [Doctoral Dissertation]. McGill University; 1986. Available from: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g

University of Manchester

14. Mcdermott, Siofra. Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function.

Degree: 2015, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718

► Since the introduction of coffee to Europe in the early 17th century its popularity has steadily increased and, water apart, is the most widely consumed… (more)

▼ Since the introduction of coffee to Europe in the early 17th century its popularity has steadily increased and, water apart, is the most widely consumed beverage globally. Being derived from a plant, a cup of coffee represents a complex mixture of naturally occurring chemicals such as caffeine, coffee oils and chlorogenic acid. As the popularity for coffee has grown so too has the interest surrounding its possible biological and pharmacological effects. A small number of studies suggest potential risks and benefits associated with coffee consumption in pregnancy; however these have yet to provide definitive conclusions. Furthermore government advice does not directly address coffee intake during pregnancy and there is no information regarding womens’ and midwives’ views and opinions on this increasingly important issue. This was a mixed-method research study, with both a qualitative and quantitative components. Firstly, I aimed to gain insight into womens’ and midwives’ views and opinions on coffee consumption during pregnancy. Informed written consent was obtained from women attending the hospital for their antenatal care. These women were of varying gestational age, ethnic background, socioeconomic status and age. Informed written consent was also obtained from midwives from varying disciplines and experience levels; those from academia, research and practicing midwives included. I recruited twenty participants in each group. Information and perspectives were gathered through semi-structured face-to-face or telephone interviews. Interviews were analysed with the Framework method of analysis. The second quantitative arm of my study investigated the effect of specific coffee chemicals on placental and myometrial vascular function. Human chorionic plate arteries, isolated from placental biopsies, and maternal myometrial arteries isolated from myometrial biopsies, were assessed by wire myography. Contraction and relaxation were determined to incremental doses of caffeic acid, chlorogenic acid and caffeine. The antioxidative properties of these chemicals were also assessed in response to application of reactive oxygen species.My findings indicated that women and midwives’ were unsure of the information surrounding coffee consumption. Pregnant women and midwives’ discussed the provision of information, sources of information and supplementing information. Findings also indicated that the relationship between health care professional and pregnant women can influence willingness to accept information and womens’ level of pregnancy stress. My laboratory studies indicated that the active coffee chemicals did not significantly impact on placental or myometrial arterial function. The chemicals investigated did not elicit any significant protective antioxidative effects. Combining methods allowed for a more comprehensive primary study to be completed. My literature search indicated that there was a clear gap in the knowledge surrounding coffee and its consumption during pregnancy. There is a clear lack of evidence-based… Advisors/Committee Members: LAVENDER, TINA T, Wareing, Mark, Lavender, Tina.

Subjects/Keywords: Coffee; Pregnancy

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APA (6^th Edition):

Mcdermott, S. (2015). Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718

Chicago Manual of Style (16^th Edition):

Mcdermott, Siofra. “Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function.” 2015. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718.

MLA Handbook (7^th Edition):

Mcdermott, Siofra. “Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function.” 2015. Web. 26 Feb 2021.

Vancouver:

Mcdermott S. Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2021 Feb 26]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718.

Council of Science Editors:

Mcdermott S. Coffee and Pregnancy: Attitudes, Consumption and Maternal Vascular Function. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718

University of British Columbia

15. Powell, Martha Bauder. Ethnography of pregnancy in our culture.

Degree: MA- MA, Sociology, 1972, University of British Columbia

URL: http://hdl.handle.net/2429/33438

► The essay describes ethnographically some of the special experiences of married women during pregnancy. Data were collected among middle class women in Vancouver, British Columbia,… (more)

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Powell, M. B. (1972). Ethnography of pregnancy in our culture. (Masters Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/33438

Chicago Manual of Style (16^th Edition):

Powell, Martha Bauder. “Ethnography of pregnancy in our culture.” 1972. Masters Thesis, University of British Columbia. Accessed February 26, 2021. http://hdl.handle.net/2429/33438.

MLA Handbook (7^th Edition):

Powell, Martha Bauder. “Ethnography of pregnancy in our culture.” 1972. Web. 26 Feb 2021.

Vancouver:

Powell MB. Ethnography of pregnancy in our culture. [Internet] [Masters thesis]. University of British Columbia; 1972. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2429/33438.

Council of Science Editors:

Powell MB. Ethnography of pregnancy in our culture. [Masters Thesis]. University of British Columbia; 1972. Available from: http://hdl.handle.net/2429/33438

Michigan State University

16. Does, Richard Bowditch. Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.

Degree: MA, Dept. of Psychology, 1965, Michigan State University

URL: http://etd.lib.msu.edu/islandora/object/etd:15764

Subjects/Keywords: Pregnancy

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APA (6^th Edition):

Does, R. B. (1965). Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:15764

Chicago Manual of Style (16^th Edition):

Does, Richard Bowditch. “Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.” 1965. Masters Thesis, Michigan State University. Accessed February 26, 2021. http://etd.lib.msu.edu/islandora/object/etd:15764.

MLA Handbook (7^th Edition):

Does, Richard Bowditch. “Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.” 1965. Web. 26 Feb 2021.

Vancouver:

Does RB. Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. [Internet] [Masters thesis]. Michigan State University; 1965. [cited 2021 Feb 26]. Available from: http://etd.lib.msu.edu/islandora/object/etd:15764.

Council of Science Editors:

Does RB. Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. [Masters Thesis]. Michigan State University; 1965. Available from: http://etd.lib.msu.edu/islandora/object/etd:15764

University of Aberdeen

17. Lamont, Kathleen A. Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.

Degree: PhD, 2019, University of Aberdeen

URL: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011

► Background: Previous meta-analyses assessing risk of recurrent stillbirth were limited by clinical and statistical heterogeneity. This study aimed to address these limitations using individual participant… (more)

▼ Background: Previous meta-analyses assessing risk of recurrent stillbirth were limited by clinical and statistical heterogeneity. This study aimed to address these limitations using individual participant data (IPD). Methods: An online survey of perinatal databases in high-income countries identified potential datasets for inclusion in the IPD meta-analysis. IPD from Scotland, Finland and Malta were analysed to calculate risk of stillbirth in a second or subsequent pregnancy using logistic regression and survival analysis. The chance of having another stillbirth if previous stillbirth was explained or unexplained was also investigated. Results: The pooled dataset included 1,068,258 women, 3,529 with a stillbirth and 1,064,729 with a livebirth in a second pregnancy. Women with a stillbirth in a second pregnancy had increased odds of stillbirth in a previous pregnancy, adjusted OR 3.41, 95% CI (2.72 TO 4.28). Increasing maternal age, overweight and obesity, having no partner, lower social class, smoking during pregnancy and short (1 year or less) and long (≥6 years) interpregnancy intervals were independent risk factors for stillbirth in a second pregnancy as were placental abruption, diabetes, threatened miscarriage, intra-uterine growth restriction and cord or hand prolapse. Compared to women who had a livebirth in a first pregnancy, women who had a stillbirth were more likely to have a subsequent stillbirth, adjusted HR 2.25, 95% CI (1.86 to 2.72). Women who were younger than 20, smoked, deprived, had no partner, had diabetes mellitus, preeclampsia, placental abruption or growth restricted foetus in their first pregnancy were also more likely to have a subsequent stillbirth. There was no difference in the risk of subsequent stillbirth whether the previous stillbirth was explained or unexplained (OR .0.92, 95% CI 0.64 to 1.32). Conclusion: Women with a stillbirth in a first pregnancy have a higher risk of recurrence in a subsequent pregnancy even when the cause is unknown.

Subjects/Keywords: Pregnancy; Stillbirth

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APA (6^th Edition):

Lamont, K. A. (2019). Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. (Doctoral Dissertation). University of Aberdeen. Retrieved from https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011

Chicago Manual of Style (16^th Edition):

Lamont, Kathleen A. “Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.” 2019. Doctoral Dissertation, University of Aberdeen. Accessed February 26, 2021. https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011.

MLA Handbook (7^th Edition):

Lamont, Kathleen A. “Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.” 2019. Web. 26 Feb 2021.

Vancouver:

Lamont KA. Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. [Internet] [Doctoral dissertation]. University of Aberdeen; 2019. [cited 2021 Feb 26]. Available from: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011.

Council of Science Editors:

Lamont KA. Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. [Doctoral Dissertation]. University of Aberdeen; 2019. Available from: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011

University of Zambia

18. Kakonkanya-Kambole, Gertrude Namunji. Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District .

Degree: 2011, University of Zambia

URL: http://hdl.handle.net/123456789/564

► Malaria infection during pregnancy is a major public health problem in the tropical and subtropical regions of the world. Pregnant women in developing countries are… (more)

▼ Malaria infection during pregnancy is a major public health problem in the tropical and subtropical regions of the world. Pregnant women in developing countries are the worst affected. Malaria in pregnancy has serious consequences both to the mother and her baby. It leads to abortion, prematurity, low birth weight, foetal death, neonatal death, severe anaemia and maternal death. The current stratagem in the prevention of malaria in pregnancy includes use of ITNs and IPT/SP. The purpose of this study was to determine the effectiveness of IPT/SP in clearing placental malaria parasites in pregnant women in Kafue District. A case-control study was conducted in two health centres in Kafue District. The cases were the postnatal women whose placentas had malaria parasites. The controls comprised of postnatal women whose placentas had no malaria parasites. The study was conducted in two health centres in Kafue District. Data was analyzed using SPSS software. Chi-Squared [x²], Fisher’s exact test and Odds Ratio (OR) were used. Multivariate logistic regression analysis was used to control for confounding factors. Statistical significance was achieved if p<0.05. Totals of 25 cases and 146 controls were enrolled into the study. Compared to the age at which the woman started attending ANC [booking] of above 20 weeks, those who started at gestational age of 12-20 weeks were 49% [p=0.002] less likely to be cases. Compared to the gestational age when the woman had her last dose of IPT of more than 36 weeks, those who had the last dose at less than 36 weeks of gestational period/age were 4.46 [p=0.001] times more likely to be cases. Compared to HIV negative women, those who were positive were 1.73 [p=0.014] times more likely to be cases.In conclusion, the study revealed that the effectiveness of IPT/SP in clearance of placental malaria parasites in pregnancy in Kafue District is affected by three factors. These include timing for antenatal booking, frequency of antenatal visits as well as the HIV status of the antenatal woman.

Subjects/Keywords: Sulphadoxine-Pyrimethamine-Pregnancy; Malaria Parasites-Pregnancy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kakonkanya-Kambole, G. N. (2011). Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District . (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/564

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kakonkanya-Kambole, Gertrude Namunji. “Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District .” 2011. Thesis, University of Zambia. Accessed February 26, 2021. http://hdl.handle.net/123456789/564.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kakonkanya-Kambole, Gertrude Namunji. “Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District .” 2011. Web. 26 Feb 2021.

Vancouver:

Kakonkanya-Kambole GN. Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District . [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/123456789/564.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kakonkanya-Kambole GN. Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District . [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/564

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

19. Katayamoyo, Patrick. Determinants of Teenage Pregnancy in Lusaka District .

Degree: 2011, University of Zambia

URL: http://hdl.handle.net/123456789/752

► A pregnant teenager who drops out of school has her child predisposed to live in abject poverty as she joins the poverty cycle. Society pays… (more)

▼ A pregnant teenager who drops out of school has her child predisposed to live in abject poverty as she joins the poverty cycle. Society pays a heavy price for children who are likely to lack proper parenting, economic security and at high risk of behavioral problems and vices such as crime, substance abuse and prostitution. Additionally there are serious and sometimes irreversible effects on the mother such as the emotional, psychological and gynaecological complications. The burden of reproductive health problems falls largely on female adolescents. Maternity registry statistics specifically reveal significantly high numbers of teenagers passing through these centers. This was a major thrust of this study, which intended to determine the predisposing factors to teenage pregnancy in order to add to the body of knowledge on the subject of teenage pregnancy and make necessary recommendations based on evidence. This research was a case control study. The study population were female teenagers (13 to 19 years old) attending clinic at centers where antenatal services are available. The sample populations were two groups of female teenagers. One group constituted cases comprising pregnant teenagers attending antenatal clinic and another group constituted controls comprising female non-pregnant teenagers attending same clinic for any other ailments (with no reported history of pregnancy or abortion). Selection of sites was purposive of four clinics with the highest teenage delivery rates in Lusaka as well as University Teaching Hospital (UTH). Sample size was determined through an initial pilot study. Data was collected using a structured questionnaire through direct (one to one) interviews. Analysis of data resulted in testing the association of the various exposure factors i.e. socio-demographic, contraception, tradition and culture and illicit sex. The results on multivariate backward logistics regression indicated the following: teenagers below 16 years were 70% less likely to get pregnant compared to those above, singles were 60% less likely to be pregnant compared to those who are married, while participants with breadwinners who were not in gainful employment were two times more likely to get pregnant. Parental/guardian reprimand was shown to have a deterrent effect on teenage pregnancy. Lack of knowledge on female physiology or hormones was shown to predispose to teenage pregnancy by three times whereas lack of knowledge on condoms had similar effect by twofold. Shyness to access contraceptives by teenagers increased chances of pregnancy by fifty percent.

Subjects/Keywords: Pregnancy; Pregnant School Girls; Teenage Pregnancy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Katayamoyo, P. (2011). Determinants of Teenage Pregnancy in Lusaka District . (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/752

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Katayamoyo, Patrick. “Determinants of Teenage Pregnancy in Lusaka District .” 2011. Thesis, University of Zambia. Accessed February 26, 2021. http://hdl.handle.net/123456789/752.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Katayamoyo, Patrick. “Determinants of Teenage Pregnancy in Lusaka District .” 2011. Web. 26 Feb 2021.

Vancouver:

Katayamoyo P. Determinants of Teenage Pregnancy in Lusaka District . [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/123456789/752.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Katayamoyo P. Determinants of Teenage Pregnancy in Lusaka District . [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/752

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia

20. Kaluba, Longa. Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia .

Degree: 2015, University of Zambia

URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310

► Background: Hypertensive disease in pregnancy continues to be one of the leading cause of maternal death. Pregnancy induced hypertension (PIH) is said to be accompanied… (more)

▼ Background: Hypertensive disease in pregnancy continues to be one of the leading cause of maternal death. Pregnancy induced hypertension (PIH) is said to be accompanied by several cardiovascular pathophysiological changes including increases in arterial stiffness. Pulse wave velocity (PWV) is the method for measuring arterial stiffness. Both the pulse wave form and the velocity are said to change in PIH. However, studies documenting these characteristics of PWV have mainly been in the Caucasian population. Aims & Objectives: To establish the characteristics of PWV in normotensive and hypertensive pregnant women at the UTH in Lusaka, Zambia. Methodology: This cross-sectional study comprised of 34 systemically selected pregnant women between the ages 18-45 years old who met the criteria. A structured interview was used to collect socio demographic data. Participants’ weights and heights were then measured. After a 15 minute rest, peripheral systolic and diastolic BP were measured using an Omron M6 comfort automatic BP monitor. The PWV measurement involved applying non-invasive piezoelectric sensors over the skin after palpating for the carotid artery on the neck and the radial artery on the wrist (carotid-radial segment C-R PWV); and for the carotid-femoral segment (C-F PWV) palpation was donefor the carotid artery on the neck and the femoral artery on the inner thigh. Using IBM® SPSS® version 20.0, analyses included: kruskal-wallis, mann- whitney tests and spearman correlation tests. A 95% confidence interval (CI) and P-value of < 0.05 were set. Results: Quality recordings were obtained from C-R PWV process (p=0.041) between normotensive and hypertensive participants. There were significant increase in AP indicating an increase in pressure difference from the systolic shoulder to its peak (p=0.046). There is also a significant increase in Aix indicating an increase in arterial stiffness (p=0.031). This is further supported by a significant difference in PWV. Results from the C-F procedure experienced severe anatomical influences of the pregnant uterus and should therefore be ignored. Conclusion: Distinct differences were seen in the waveform and PWV amongst individuals with PIH. This supports the vascular changes said to take place in PIH. Thus, PWV can be used as a measure for arterial stiffness and in the screening of PIH and possible treatment

Subjects/Keywords: Hypertension in pregnancy; Pregnancy Complications, Cardiovascular

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Kaluba, L. (2015). Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia . (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kaluba, Longa. “Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia .” 2015. Thesis, University of Zambia. Accessed February 26, 2021. http://dspace.unza.zm:8080/xmlui/handle/123456789/4310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kaluba, Longa. “Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia .” 2015. Web. 26 Feb 2021.

Vancouver:

Kaluba L. Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia . [Internet] [Thesis]. University of Zambia; 2015. [cited 2021 Feb 26]. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kaluba L. Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia . [Thesis]. University of Zambia; 2015. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hawaii – Manoa

21. Elia, Jennifer. An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.

Degree: 2017, University of Hawaii – Manoa

URL: http://hdl.handle.net/10125/51039

►

D.P.H. University of Hawaii at Manoa 2015.

About half of all pregnancies in the United States are unintended (mistimed or unwanted), and this figure has… (more)

▼

D.P.H. University of Hawaii at Manoa 2015.

About half of all pregnancies in the United States are unintended (mistimed or unwanted), and this figure has held steady for decades despite recognition as a public health priority and efforts to reduce it. Unintended pregnancy has been associated with negative health and social outcomes for mother and child. Hawai‘i has the second highest unintended pregnancy rate in the U.S., and Native Hawaiians appear to have the highest rates of unintended pregnancy among the state’s major ethnic groups. The purpose of this dissertation was to examine unintended pregnancy in Hawai‘i, with a particular focus on Native Hawaiians, in terms of how different groups are affected (disparities), how it is assessed (measurement), and how it is conceptualized (meanings). The first of three studies used data from the Hawai‘i Pregnancy Risk Assessment Monitoring System to examine disparities by race/ethnicity and other maternal characteristics in: pregnancy intention; trying to get pregnant; discordant responses for intention and trying; contraceptive use before pregnancy; and “didn’t mind” pregnancy as a reason for contraceptive non-use. The second study examined three measures of pregnancy intention – the London Measure of Unplanned Pregnancy (LMUP), National Survey of Family Growth (NSFG) intention categories, and “trying” to get pregnant – in relation to demographic characteristics and pregnancy outcome (prenatal care vs. abortion) through a survey of pregnant women in Honolulu. With eight focus groups of Native Hawaiian women and men, the third study qualitatively described factors related to pregnancy planning and decision-making within this community. Findings from these three studies speak to the complexity of pregnancy intention and its importance to public health. Many women in Hawai‘i became pregnant when they were not intending, trying, and/or wanting to get pregnant. Furthermore, a substantial proportion of women reported ambivalence towards their pregnancies and did not use contraception despite being “at risk” for unintended pregnancy. Disparities by race/ethnicity and other demographic characteristics were significant in bivariate and multivariate analyses. Cultural factors and social norms may influence the perception and impact of unintended pregnancy among Native Hawaiians. Suggestions for further quantitative and qualitative research and other implications are described.

Subjects/Keywords: Native Hawaiian; unintended pregnancy; pregnancy ambivalence; disparities

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Elia, J. (2017). An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/51039

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Elia, Jennifer. “An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.” 2017. Thesis, University of Hawaii – Manoa. Accessed February 26, 2021. http://hdl.handle.net/10125/51039.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Elia, Jennifer. “An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.” 2017. Web. 26 Feb 2021.

Vancouver:

Elia J. An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. [Internet] [Thesis]. University of Hawaii – Manoa; 2017. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10125/51039.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Elia J. An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. [Thesis]. University of Hawaii – Manoa; 2017. Available from: http://hdl.handle.net/10125/51039

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech

22. Labrum, Mandaran Lynn. Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.

Degree: MS, Human Development, 2014, Virginia Tech

URL: http://hdl.handle.net/10919/64196

► This research explores the influence of pregnancy loss and coping strategies employed while connecting to the fetus in a subsequent pregnancy following a late term… (more)

Subjects/Keywords: pregnancy loss; subsequent pregnancy; coping; connection; attachment

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APA (6^th Edition):

Labrum, M. L. (2014). Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/64196

Chicago Manual of Style (16^th Edition):

Labrum, Mandaran Lynn. “Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.” 2014. Masters Thesis, Virginia Tech. Accessed February 26, 2021. http://hdl.handle.net/10919/64196.

MLA Handbook (7^th Edition):

Labrum, Mandaran Lynn. “Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.” 2014. Web. 26 Feb 2021.

Vancouver:

Labrum ML. Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. [Internet] [Masters thesis]. Virginia Tech; 2014. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/10919/64196.

Council of Science Editors:

Labrum ML. Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. [Masters Thesis]. Virginia Tech; 2014. Available from: http://hdl.handle.net/10919/64196

Drexel University

23. Evans, Amy N. Social Problem Solving and Psychological Distress among Pregnant Women.

Degree: 2013, Drexel University

URL: http://hdl.handle.net/1860/idea:6547

►

Animal and human studies have provided evidence that psychological distress during pregnancy may adversely affect the physical and psychological health of the child and mother.… (more)

Subjects/Keywords: Psychology; Pregnancy – Psychological aspects; Pregnancy – Social aspects

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Evans, A. N. (2013). Social Problem Solving and Psychological Distress among Pregnant Women. (Thesis). Drexel University. Retrieved from http://hdl.handle.net/1860/idea:6547

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Evans, Amy N. “Social Problem Solving and Psychological Distress among Pregnant Women.” 2013. Thesis, Drexel University. Accessed February 26, 2021. http://hdl.handle.net/1860/idea:6547.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Evans, Amy N. “Social Problem Solving and Psychological Distress among Pregnant Women.” 2013. Web. 26 Feb 2021.

Vancouver:

Evans AN. Social Problem Solving and Psychological Distress among Pregnant Women. [Internet] [Thesis]. Drexel University; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1860/idea:6547.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Evans AN. Social Problem Solving and Psychological Distress among Pregnant Women. [Thesis]. Drexel University; 2013. Available from: http://hdl.handle.net/1860/idea:6547

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta

24. Merchant, Neelam. Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda.

Degree: MSin Global Health, Department of Public Health Sciences, 2010, University of Alberta

URL: https://era.library.ualberta.ca/files/fq977v02q

► The focus of this study is to understand why, despite high uptake of antenatal care, women in Uganda continue to deliver without skilled birth attendants.… (more)

Subjects/Keywords: childbirth; Uganda; pregnancy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Merchant, N. (2010). Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/fq977v02q

Chicago Manual of Style (16^th Edition):

Merchant, Neelam. “Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda.” 2010. Masters Thesis, University of Alberta. Accessed February 26, 2021. https://era.library.ualberta.ca/files/fq977v02q.

MLA Handbook (7^th Edition):

Merchant, Neelam. “Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda.” 2010. Web. 26 Feb 2021.

Vancouver:

Merchant N. Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda. [Internet] [Masters thesis]. University of Alberta; 2010. [cited 2021 Feb 26]. Available from: https://era.library.ualberta.ca/files/fq977v02q.

Council of Science Editors:

Merchant N. Decision-making related to pregnancy and childbirth in Kabarole district, western Uganda. [Masters Thesis]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/fq977v02q

University of Alberta

25. Dolson, Kirsti. Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy.

Degree: MA, Faculty of Physical Education and Recreation, 2011, University of Alberta

URL: https://era.library.ualberta.ca/files/vx021f40t

► The purpose of this study was to determine how two elite female marathon runners used narrative to describe their lived bodily experiences during pregnancy. Information… (more)

Subjects/Keywords: pregnancy; narratives; runners

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Dolson, K. (2011). Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/vx021f40t

Chicago Manual of Style (16^th Edition):

Dolson, Kirsti. “Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy.” 2011. Masters Thesis, University of Alberta. Accessed February 26, 2021. https://era.library.ualberta.ca/files/vx021f40t.

MLA Handbook (7^th Edition):

Dolson, Kirsti. “Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy.” 2011. Web. 26 Feb 2021.

Vancouver:

Dolson K. Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy. [Internet] [Masters thesis]. University of Alberta; 2011. [cited 2021 Feb 26]. Available from: https://era.library.ualberta.ca/files/vx021f40t.

Council of Science Editors:

Dolson K. Narratives of Elite Runners: descriptions of their bodily experiences during pregnancy. [Masters Thesis]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/vx021f40t

26. 阿南, あゆみ. Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.

Degree: 博士（看護学）, 2013, Kyushu University / 九州大学

URL: http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736

► This study aimed to investigate the effects of working during gestation on pregnant women by evaluating their mental and physical stress. The subjects were 62… (more)

Subjects/Keywords: Pregnancy; Working; Stress

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APA (6^th Edition):

阿南, �. (2013). Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. (Thesis). Kyushu University / 九州大学. Retrieved from http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

阿南, あゆみ. “Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.” 2013. Thesis, Kyushu University / 九州大学. Accessed February 26, 2021. http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

阿南, あゆみ. “Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.” 2013. Web. 26 Feb 2021.

Vancouver:

阿南 �. Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. [Internet] [Thesis]. Kyushu University / 九州大学; 2013. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

阿南 �. Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. [Thesis]. Kyushu University / 九州大学; 2013. Available from: http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manchester

27. Hannam, Kimberly. The effects of air pollution on perinatal outcomes in North West England.

Degree: 2013, University of Manchester

URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713

► Over the past decade there has been a substantial increase in evidence suggesting an increased risk of adverse pregnancy outcomes from ambient air pollution exposure.… (more)

▼ Over the past decade there has been a substantial increase in evidence suggesting an increased risk of adverse pregnancy outcomes from ambient air pollution exposure. However, there is yet to be enough convincing evidence to confirm a causal link between specific air pollutants and adverse pregnancy outcomes. The objective of this project was to address the paucity of evidence from the UK on the risk from air pollution in pregnancy. The research aim was to investigate the effects of ambient air pollution on adverse pregnancy outcomes using retrospective birth outcome data from the ‘North West Perinatal Survey Unit’ (NWPSU) during the period 2004 to 2008.In addition, primarily to determine the most appropriate exposure estimation method, a prospective comparison study (n=85) was performed to compare personal measurements of nitrogen oxides (NOx) and specifically nitrogen dioxide (NO₂) with commonly used exposure estimation techniques. This study informed two further studies which quantified the effects from air pollution in pregnancy using a large retrospective cohort from the NWPSU. The first, investigated the effects of maternal residential proximity to major roads on low birthweight (LBW), small for gestational age (SGA) and preterm birth (PTB). The second, investigated the effects of NOx, NO₂, carbon monoxide (CO) and particulate matter (PM₂.₅ and PM₁₀) based on estimates from a novel spatio-temporal air pollution model and stationary monitor sites on SGA, PTB and mean birth weight change. Linear and logistic regression models were used to quantify the risk of adverse pregnancy outcomes from living in close proximity to a major road and to specific ambient pollutants. Odds ratio (OR) associations and mean birth weight change were calculated for each of the pollutants with exposure averaged over the entire pregnancy and for specific pregnancy periods to establish critical windows of exposure. Models were adjusted for maternal age, ethnicity, parity, socio-economic status, birth season, body mass index and smoking.No statistically significant associations were found between living <200m from a major road and adverse pregnancy outcomes. Based on the spatio-temporal modelled air pollution estimates, an increased risk of SGA was found in later pregnancy with NO₂ (OR=1.14, 95%CI= 1.00-1.30), CO (OR=1.21, 1.02-1.42), PM₂.₅ (OR=1.10, 1.00-1.21) and PM₁₀ (OR=1.12, 1.00-1.25). This study provides additional evidence that women exposed to high air pollution concentrations in pregnancy are at an increased risk of an SGA birth, but not for PTB. However, there was no evidence of an effect on SGA for exposures below the current legal air quality limits. Advisors/Committee Members: SIBLEY, COLIN CP, AGIUS, RAYMOND R, Mcnamee, Roseanne, Sibley, Colin, Agius, Raymond.

Subjects/Keywords: Air pollution; Pregnancy

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APA (6^th Edition):

Hannam, K. (2013). The effects of air pollution on perinatal outcomes in North West England. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713

Chicago Manual of Style (16^th Edition):

Hannam, Kimberly. “The effects of air pollution on perinatal outcomes in North West England.” 2013. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021. http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713.

MLA Handbook (7^th Edition):

Hannam, Kimberly. “The effects of air pollution on perinatal outcomes in North West England.” 2013. Web. 26 Feb 2021.

Vancouver:

Hannam K. The effects of air pollution on perinatal outcomes in North West England. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2021 Feb 26]. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713.

Council of Science Editors:

Hannam K. The effects of air pollution on perinatal outcomes in North West England. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713

Cornell University

28. Sones, Jenny. Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.

Degree: PhD, Physiology, 2015, Cornell University

URL: http://hdl.handle.net/1813/39356

► Preeclampsia (PE) is a devastating disorder of pregnancy that affects 10% of pregnancies worldwide. While it is a leading cause of perinatal morbidity and mortality,… (more)

▼ Preeclampsia (PE) is a devastating disorder of pregnancy that affects 10% of pregnancies worldwide. While it is a leading cause of perinatal morbidity and mortality, the cause of PE is unknown. To date the only definitive treatment is delivery of the placenta and the baby, which is often preterm and/or growth restricted. The origins of PE are generally regarded to be early in pregnancy at the time of placenta formation as placental developmental abnormalities often characterize PE pregnancies. In these thesis studies, early pregnancy events required for proper placentation, implantation and decidualization, were investigated in the BPH/5 spontaneous mouse model of PE. We discovered profound developmental defects in implantation, decidualization, and placentation in BPH/5 mice. Along with evidence of decidual hypoxia, these defects were associated with a distinct molecular signature of aberrant embryo-uterine interactions. We identified significant dysregulation in the periimplantation period, particularly in the overexpression of cyclooxygenase 2 (Cox2) in the maternal uterine environment. Using pharmacological intervention at early pregnancy with a selective Cox2 inhibitor, we confirmed that defects in Cox2 signaling during the periimplantation period have "ripple effects" impacting downstream adverse pregnancy outcomes at mid and late gestation in BPH/5 mice, including fetal growth restriction and demise. Finally, investigations in the periimplantation period lead us to discover deficiencies in immunoregulatory pathways crucial for placental development at the maternal-fetal interface in BPH/5 mice. We showed dramatic loss of decidual Natural Killer (dNK) cells and this was associated with overexpression of IL-15 in BPH/5 implantation sites. Furthermore, we linked Cox2 inhibition with a reduction in IL-15. Altogether, this points towards inflammation in the maternal uterine environment during early pregnancy having a central role in the poor fetoplacental and pregnancy outcomes associated with this model and highlights Cox2 inhibitors as potential therapeutics to prevent fetal morbidity/mortality associated with PE. Importantly, our data supports the "ripple effect" hypothesis that defects in early pregnancy events are the source of downstream adverse pregnancy outcomes using the BPH/5 mouse model of PE. Advisors/Committee Members: Davisson, Robin L (chair), Cohen, Paula (committee member), Roberson, Mark Stephen (committee member), Quirk, Susan Mary (committee member).

Subjects/Keywords: preeclampsia; pregnancy; placenta

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sones, J. (2015). Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/39356

Chicago Manual of Style (16^th Edition):

Sones, Jenny. “Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.” 2015. Doctoral Dissertation, Cornell University. Accessed February 26, 2021. http://hdl.handle.net/1813/39356.

MLA Handbook (7^th Edition):

Sones, Jenny. “Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.” 2015. Web. 26 Feb 2021.

Vancouver:

Sones J. Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1813/39356.

Council of Science Editors:

Sones J. Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/39356

Cornell University

29. Wilkinson, Amanda. Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.

Degree: PhD, Nutrition, 2015, Cornell University

URL: http://hdl.handle.net/1813/40599

► Maternal HIV infection during pregnancy is associated with increased risk of adverse obstetric and infant outcomes, and understanding the factors responsible for this association is… (more)

▼ Maternal HIV infection during pregnancy is associated with increased risk of adverse obstetric and infant outcomes, and understanding the factors responsible for this association is essential for designing effective interventions. Maternal malnutrition is an important determinant of maternal and infant health for both HIV-infected and - uninfected women. However, the relative contributions of food insecurity and infectioninduced changes in appetite and body weight regulation that alone, or in combination, contribute to malnutrition among HIV-infected women is largely unknown. The goal of this research was to advance the understanding of the underlying mechanisms by which maternal HIV infection influences pregnancy and early childhood outcomes. A prospective cohort of 114 pregnant women of mixed HIV-status was established in northwestern Tanzania. Pregnant women were followed through delivery and mother-infant dyads participated in follow-up visits at 1, 2, 3 and 6 months postpartum. This study had three main research aims: (1) to investigate maternal HIV and maternal anthropometric indicators as potential determinants of infant outcomes, (2) to characterize maternal and umbilical cord blood cytokine profiles and relate these to infant outcomes, and (3) to evaluate maternal cachexia characteristics during pregnancy. Maternal HIV status and maternal gestational mid-upper arm circumference (MUAC) were compared to infant anthropometric measurements from birth to six months of age. Infants born to HIV-infected mothers weighed, on average, 235 g less and were 1 cm shorter at birth compared to those born to HIV-uninfected mothers. Among mothers of mixed HIV-status, infants born to women with low MUAC had lower birth length and head circumference than infants born to women with higher MUAC. Maternal HIVinfection and low MUAC were also associated with poorer infant growth indicators through six months postpartum. Examination of cytokine profiles during pregnancy in this cohort revealed that HIV-infected pregnant women experienced elevated tumor necrosis factor (TNF)-[alpha]inflammation compared to HIV-uninfected pregnant women. On average, TNF-[alpha] concentrations were 14% higher among HIV-infected pregnant women. Among HIVinfected women, longer duration of antiretroviral therapy and more aggressive antiretroviral therapy were associated with more favorable cytokine profiles. Umbilical cord blood cytokine concentrations were used as a proxy for intrauterine exposure. Elevated umbilical cord blood cytokine concentrations were associated with lower infant birth weight and length. Pregnant women were also evaluated based on biopsychosocial characteristics related to cachexia. Based on a modified cachexia scoring system, HIV-infected and HIV-uninfected pregnant women had comparable cachexia symptoms. Evidence of increased gestational cachexia was associated with less favorable infant birth anthropometrics; and, among HIV-infected mothers, cachexia score was associated with lower infant weight-for-age and length-for-age… Advisors/Committee Members: McDermid,Joann M. (chair), Lujan,Marla E. (committee member), Booth,James (committee member), Brannon,Patsy Marie (committee member).

Subjects/Keywords: HIV; Pregnancy; Cytokines

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wilkinson, A. (2015). Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/40599

Chicago Manual of Style (16^th Edition):

Wilkinson, Amanda. “Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.” 2015. Doctoral Dissertation, Cornell University. Accessed February 26, 2021. http://hdl.handle.net/1813/40599.

MLA Handbook (7^th Edition):

Wilkinson, Amanda. “Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.” 2015. Web. 26 Feb 2021.

Vancouver:

Wilkinson A. Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1813/40599.

Council of Science Editors:

Wilkinson A. Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/40599

Cornell University

30. Young, Melissa. Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.

Degree: PhD, Nutrition, 2011, Cornell University

URL: http://hdl.handle.net/1813/33570

► Iron deficiency anemia is the most common nutrient deficiency in the world , with highest rates in pregnant women and young children. Despite the magnitude… (more)

▼ Iron deficiency anemia is the most common nutrient deficiency in the world , with highest rates in pregnant women and young children. Despite the magnitude and severity of iron deficiency, there remains gaps in our knowledge of iron metabolism. Hepcidin is a key regulator of iron homeostasis yet limited data is available on its role during pregnancy. Although our knowledge of non-heme iron metabolism has increased substantially in recent years, the mechanisms regulating heme iron metabolism remain elusive. The overall goal o f this research is to further understand the primary determinants of iron absorption and placental iron transfer in women of childbearing age. To address these issues stable iron isotopes (57Fe and 58Fe) were used to measure iron absorption in non-pregnant (ages 18-32 years, n = 30) and pregnant (ages 16-32 years, n = 20) subjects and placental iron transfer in pregnant women. Nonheme iron absorption was inversely associated with iron status and serum hepcidin. However, heme iron absorption was not signif icantly associated with serum hepcidin or iron stores, suggesting differential regulation. In a subset of 18 non-pregnant subjects serum prohepcidin (hepcidin precursor) was also assessed but was not significantly associated with measures of iron absorptio n or serum hepcidin. Both pregnant and non-pregnant women absorbed significantly more iron from a heme based meal compared to a non-heme iron supplement. Interestingly there also appears to be preferential fetal utilization of maternally ingested heme iron compared to nonheme iron during pregnancy. Iron status in the maternal-neonatal dyad and maternal serum hepcidin were inversely associated with heme and non-heme placental iron transfer. In a cohort of 92 pregnant adolescents (ages 14-18 years), the placental protein expression of transferrin receptor was likewise increased in response to altered iron stores in the mother and neonate. Despite increased iron absorption by women during pregnancy, placental iron transporter expression and placental iron tr ansfer, many of the mothers and the neonates had suboptimal iron status at the time of delivery. Based on study results, further research on the mechanisms of heme iron metabolism and mechanisms of placental iron transfer are warranted. Advisors/Committee Members: O'Brien, Kimberly O (chair), Haas, Jere Douglas (committee member), Pinstrup-Anderson, Per (committee member), Olson, Christine Marie (committee member).

Subjects/Keywords: Iron; Pregnancy; Hepcidin

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Young, M. (2011). Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/33570

Chicago Manual of Style (16^th Edition):

Young, Melissa. “Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.” 2011. Doctoral Dissertation, Cornell University. Accessed February 26, 2021. http://hdl.handle.net/1813/33570.

MLA Handbook (7^th Edition):

Young, Melissa. “Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.” 2011. Web. 26 Feb 2021.

Vancouver:

Young M. Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. [Internet] [Doctoral dissertation]. Cornell University; 2011. [cited 2021 Feb 26]. Available from: http://hdl.handle.net/1813/33570.

Council of Science Editors:

Young M. Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. [Doctoral Dissertation]. Cornell University; 2011. Available from: http://hdl.handle.net/1813/33570

Open Access Theses and Dissertations