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Rutgers University
1.
Moscovitz, Jamie Esther, 1989-.
Enterohepatic nuclear receptor signaling during pregnancy.
Degree: PhD, Toxicology, 2016, Rutgers University
URL: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/
► Physiological adaptations to the intestine-liver axis during pregnancy alter the disposition of xenobiotics and endobiotics. As a result, some pregnant women experience decreased efficacy or…
(more)
▼ Physiological adaptations to the intestine-liver axis during pregnancy alter the disposition of xenobiotics and endobiotics. As a result, some pregnant women experience decreased efficacy or adverse reactions to prescription medications (xenobiotic effect), while others may become susceptible to cholestatic liver disease due to enhanced bile acid levels (endobiotic effect). The purpose of this dissertation research was to characterize molecular adaptations in enterohepatic nuclear receptor signaling and downstream bile acid and xenobiotic disposition pathways that can occur during late pregnancy. In ilea collected from mice in late gestation, an overall down-regulation of Farnesoid X Receptor (Fxr/Nr1h4) and Pregnane X Receptor (Pxr/Nr1i2) signaling, including target enzyme and transporter expression, was observed. To explore potential mechanisms, the ability of candidate sex hormones to alter the expression of enzyme and transport genes regulated by FXR and PXR were studied in human intestinal cells. In vitro studies suggest a prominent role for progesterone-mediated interference with PXR signaling in the intestine during pregnancy that could contribute to altered xenobiotic transport. Further assessment of the ability of activated Fxr to modulate hepatic and intestinal regulation of bile acid synthesis and transport pathways during pregnancy was investigated in mice. Treatment of pregnant mice with the specific Fxr agonist GW4064 restored the expression of bile acid synthesis enzymes and transporters towards levels typically observed in virgin mice. This study provides the molecular basis for a novel approach to restore bile acid homeostasis in patients with maternal cholestasis. Finally, loss-of-function studies in pregnant Fxr-null mice revealed that deficiency in the Fxr gene prevents pregnancy-mediated repression of key bile acid regulatory factors and transporters, largely in the intestines. Taken together, these data advance our understanding of alterations in chemical disposition during pregnancy, and the overall “procholestatic†state of pregnancy that sensitizes women to acquiring liver disease.
Advisors/Committee Members: Aleksunes, Lauren M (chair), Guo, Grace L (internal member), Roepke, Troy (internal member), Gallo, Michael (internal member), Thompson, Kary (outside member).
Subjects/Keywords: Pregnancy
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APA ·
Chicago ·
MLA ·
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Manager
APA (6th Edition):
Moscovitz, Jamie Esther, 1. (2016). Enterohepatic nuclear receptor signaling during pregnancy. (Doctoral Dissertation). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/51372/
Chicago Manual of Style (16th Edition):
Moscovitz, Jamie Esther, 1989-. “Enterohepatic nuclear receptor signaling during pregnancy.” 2016. Doctoral Dissertation, Rutgers University. Accessed February 26, 2021.
https://rucore.libraries.rutgers.edu/rutgers-lib/51372/.
MLA Handbook (7th Edition):
Moscovitz, Jamie Esther, 1989-. “Enterohepatic nuclear receptor signaling during pregnancy.” 2016. Web. 26 Feb 2021.
Vancouver:
Moscovitz, Jamie Esther 1. Enterohepatic nuclear receptor signaling during pregnancy. [Internet] [Doctoral dissertation]. Rutgers University; 2016. [cited 2021 Feb 26].
Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/.
Council of Science Editors:
Moscovitz, Jamie Esther 1. Enterohepatic nuclear receptor signaling during pregnancy. [Doctoral Dissertation]. Rutgers University; 2016. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/51372/

Rutgers University
2.
Parobchak, Nataliya, 1987-.
Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.
Degree: MS, Toxicology, 2020, Rutgers University
URL: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/
► The goal of this study was to characterize the expression and signaling of uterine GPR83 in vivo in the nonpregnant and pregnant mouse and in vitro in human endometrial…
(more)
▼ The goal of this study was to characterize the expression and signaling of uterine GPR83 in vivo in the nonpregnant and pregnant mouse and in vitro in human endometrial and non-endometrial cells. Expression of uterine Gpr83 was determined by quantitative polymerase chain reaction throughout the estrous cycle and during early
pregnancy in ovarian-stimulated and non−ovarian-stimulated mice and pregnant and pseudopregnant mice. Expression was also determined in ovariectomized mice after the administration of oil, E2, P4, or E2 + P4 and in stromal cells following 6 days of in vitro decidualization. GPR83 signaling was studied in human endometrial and embryonic kidney cell lines. Cells were treated with PEN, a GPR83 ligand, and PEN-induced extracellular signal-regulated kinase (ERK) phosphorylation was assayed under conditions that blocked Gαq/11 and/or β-arrestin signaling. Results show that uterine Gpr83 is expressed throughout the estrous cycle and during early
pregnancy; expression increases dramatically at the time of uterine receptivity, embryo implantation, and stromal cell decidualization. In the ovariectomized mouse, hormone add-back reveals that Gpr83 expression is highly responsive to the combined treatment of E2 and P4, and studies in the ovarian-stimulated mouse show that expression is also very sensitive to changes in E2 and P4 and is therefore tightly regulated by E2 and P4. At the implantation site, expression is elevated up to D6 of
pregnancy and then declines rapidly on D7 and D8, suggesting that if there is any involvement in decidualization, it is likely associated with primary but not secondary stromal cell decidualization. This premise was supported by the observation that stromal cell decidualization in vitro progresses with a decline in Gpr83 expression. In ERα/PR-expressing endometrial Ishikawa cells, GPR83 mediates PEN signals in a Gαq/11-dependent manner, and studies conducted in HEK 293 cells lacking β-arrestin revealed that GPR83 also signals via a β-arrestin−dependent manner. When signaling by either one or both pathways is downregulated, cells exhibit a major reduction in responsiveness to PEN treatment, demonstrating that signaling by both pathways is significant. Based on our findings, we hypothesize that PEN/GPR83 signaling regulates uterine receptivity, embryo implantation, and primary stromal cell decidualization by coupling to Gαq/11- and β-arrestin−dependent pathways.
Advisors/Committee Members: Babwah, Andy (chair), Aleksunes, Lauren (internal member), Reuhl, Kenneth (internal member), School of Graduate Studies.
Subjects/Keywords: Pregnancy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
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APA (6th Edition):
Parobchak, Nataliya, 1. (2020). Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. (Masters Thesis). Rutgers University. Retrieved from https://rucore.libraries.rutgers.edu/rutgers-lib/64942/
Chicago Manual of Style (16th Edition):
Parobchak, Nataliya, 1987-. “Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.” 2020. Masters Thesis, Rutgers University. Accessed February 26, 2021.
https://rucore.libraries.rutgers.edu/rutgers-lib/64942/.
MLA Handbook (7th Edition):
Parobchak, Nataliya, 1987-. “Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse.” 2020. Web. 26 Feb 2021.
Vancouver:
Parobchak, Nataliya 1. Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. [Internet] [Masters thesis]. Rutgers University; 2020. [cited 2021 Feb 26].
Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/.
Council of Science Editors:
Parobchak, Nataliya 1. Uterine Gpr83 expression and Gpr83 signaling during early pregnancy in the mouse. [Masters Thesis]. Rutgers University; 2020. Available from: https://rucore.libraries.rutgers.edu/rutgers-lib/64942/

University of Auckland
3.
Atkinson, Kelly Rene LeFevre.
Proteomic biomarker discovery for preeclampsia.
Degree: 2008, University of Auckland
URL: http://hdl.handle.net/2292/2565
► Preeclampsia is a serious multisystem complication of late pregnancy with adverse effects for mothers and babies. Currently this disorder is diagnosed from clinical observations occurring…
(more)
▼ Preeclampsia is a serious multisystem complication of late
pregnancy with adverse effects for mothers and babies. Currently this disorder is diagnosed from clinical observations occurring late in the disease process. Unknown factors in the maternal circulation, possibly released by the preeclamptic placenta, have been linked to the pathophysiological changes characteristic of the disorder. The research in this thesis used proteomic techniques to identify putative preeclampsia biomarkers from two sources: secreted from a placental cell line undergoing differentiation, and directly sampled from the serum and plasma of women with late-onset preeclampsia.
The first part of this research examined the secreted proteome of a placental choriocarcinoma cell line (BeWo) undergoing forskolin-mediated differentiation. Development of serum-free culture techniques enabled analysis of these secreted proteins by two-dimensional gel electrophoresis (2DE). Statistical testing revealed the significant involvement of seven spots during this differentiation model, with VE-cadherin and matrix metalloproteinase 2 among the proteins identified.
In the second part of this research, maternal serum and plasma proteins were compared from women with preeclampsia and healthy pregnant women. Serum samples were analyzed using 2DE, and plasma was subjected to difference gel electrophoresis (DIGE). Bioinformatic analysis of both datasets identified multiple spot clusters able to classify samples according to disease state. Five of these serum proteins were differentially regulated in preeclampsia, including two isoforms of apolipoprotein E whose isoform-specific expression was confirmed using western blots. Analysis of plasma from preeclamptic women identified six proteins, again including apolipoprotein E. Proteins from both studies are linked to preeclampsia pathophysiology through lipid transport, complement, and retinol transport systems.
The culture methods and secreted proteomic techniques developed in this work have uncovered proteins in a placental cell line and maternal serum and plasma that are associated with preeclampsia. These methods can be extended to any system where secreted proteins are of interest. The differentially regulated proteins found in this study provide an important first step towards developing effective biomarkers for diagnosing and/or predicting preeclampsia.
Advisors/Committee Members: Garth Cooper, Robyn North.
Subjects/Keywords: proteomics; pregnancy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Atkinson, K. R. L. (2008). Proteomic biomarker discovery for preeclampsia. (Doctoral Dissertation). University of Auckland. Retrieved from http://hdl.handle.net/2292/2565
Chicago Manual of Style (16th Edition):
Atkinson, Kelly Rene LeFevre. “Proteomic biomarker discovery for preeclampsia.” 2008. Doctoral Dissertation, University of Auckland. Accessed February 26, 2021.
http://hdl.handle.net/2292/2565.
MLA Handbook (7th Edition):
Atkinson, Kelly Rene LeFevre. “Proteomic biomarker discovery for preeclampsia.” 2008. Web. 26 Feb 2021.
Vancouver:
Atkinson KRL. Proteomic biomarker discovery for preeclampsia. [Internet] [Doctoral dissertation]. University of Auckland; 2008. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/2292/2565.
Council of Science Editors:
Atkinson KRL. Proteomic biomarker discovery for preeclampsia. [Doctoral Dissertation]. University of Auckland; 2008. Available from: http://hdl.handle.net/2292/2565

University of Namibia
4.
Mungoba, TN.
Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
.
Degree: 2015, University of Namibia
URL: http://hdl.handle.net/11070/1697
► Globally an estimate of 350 000 to 500 000 women die annually from preventable causes related to pregnancy and childbirth. An adverse pregnancy outcome is…
(more)
▼ Globally an estimate of 350 000 to 500 000 women die annually from preventable causes related to pregnancy and childbirth. An adverse pregnancy outcome is an incident which reduces the chance of having a healthy baby, two or more 1st trimester miscarriage. Previous studies reveal that adverse pregnancy outcomes were threatening the lives of both the mother and child. The burden of adverse pregnancy outcomes among women who deliver at Intermediate Hospital Oshakati is a major public health concern. It has frequently been reported in the local media that adverse pregnancy outcomes among women in Namibia is a common occurrence. The objective of this study was to determine and describe the factors associated with adverse pregnancy outcomes and compare the adverse pregnancy outcomes between teenage and older mothers. A quantitative analytical, contextual, cross-sectional study was conducted. Pregnant women who delivered at Intermediate Hospital Oshakati from July to September 2015 were interviewed, using a structured questionnaire. Information on demographic, potential risk factors and adverse pregnancy outcomes were collected and analyzed using Epi info. We enrolled a total of 306 pregnant women of whom 50% (n=153) were teenage and 50% (n=153) were older mothers. A total of n=164 (53.60%) had adverse pregnancy outcomes, whereas n=142 (46.40%) did not have adverse pregnancy outcomes. Significant bivariate results included regions (OR 0.33, 95%CI: 0.12-0.94, p=0.0314), residential areas (OR=0.43, 95%CI: 0.25-0.74, p=0.0021), gestational weeks (OR 0.75, 95%CI: 0.65-0.88, p=0.0004), BMI (OR 0.56, 95%CI: 0.32-0.98, p=0.0430), haemoglobin (OR 0.33, 95%CI: 0.16-0.69, p=0.0029), and blood pressure (OR 9.56, 95%CI: 1.19-77.5, p=0.0334). The adverse pregnancy outcomes are a real public health issue, which need to be addressed. It is recommended that each district hospitals have specialists in obstetric care and advanced midwifery, and to sensitize all pregnant women about the adverse pregnancy outcomes and how to prevent it.
Subjects/Keywords: Adverse pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mungoba, T. (2015). Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
. (Thesis). University of Namibia. Retrieved from http://hdl.handle.net/11070/1697
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Mungoba, TN. “Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
.” 2015. Thesis, University of Namibia. Accessed February 26, 2021.
http://hdl.handle.net/11070/1697.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Mungoba, TN. “Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
.” 2015. Web. 26 Feb 2021.
Vancouver:
Mungoba T. Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
. [Internet] [Thesis]. University of Namibia; 2015. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/11070/1697.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Mungoba T. Factors associated with adverse pregnancy outcomes among women who delivered at Intermediate Hospital Oshakati
. [Thesis]. University of Namibia; 2015. Available from: http://hdl.handle.net/11070/1697
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia
5.
Nusraat, Gangat.
Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
.
Degree: 2016, University of Zambia
URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796
► Background: The latent phase of labour is poorly understood and duration of this phase is significantly difficult to measure. Prolonged latent phase (PLP) accounts for…
(more)
▼ Background: The latent phase of labour is poorly understood and duration of this phase
is significantly difficult to measure. Prolonged latent phase (PLP) accounts for
abnormalities in both nulliparous and multiparous mothers and is associated with
increased risks of obstetric interventions and poor fetal outcomes.
Objectives: This study aimed to determine fetal outcomes in women admitted with a
diagnosis of PLP at the UTH.
Methods: A case control study of ratio 1:1 comprising 171 women with PLP and 168
with normal labour was examined at the UTH from July 2015 to October 2015. An
investigator administered questionnaire was used to collect data along with medical
records of neonates and mothers. Bivariate analysis and multiple logistic regression was
carried out to compare fetal outcomes in cases and controls.
Results: There were 12.3% admissions to NICU from among women with PLP and none
from controls (with normal labour). Furthermore, 9.9% of newborns with Apgar score <
7 were in women with PLP and 1.2% in controls. Caesarean section and post-partum
hemorrhage was more frequent in women with PLP than controls: 15 (8.8%) vs. 2 (1.2 %)
and (5.8% vs. 1.2%) respectively. Moreover, younger mothers had marginally higher
odds of PLP [Odds Ratio (OR) 1.10, 95% CI 1.05 – 1.15, P-value < 0.01] and women
with parity 0 had over 12 times increased odds for PLP (OR 12.29, 95% CI 4.62 – 32.67,
P-value < 0.01).
Conclusion: This study has shown that prolonged latent phase of labour is a predictor of
labour dystocia and neonatal morbidity. It is manifested by higher intervention rates such
as augmentation and operative deliveries amongst women with PLP than controls. Babies
delivered following PLP require more neonatal attention than controls. Therefore, all
women with PLP should be referred to UTH to reduce on morbidity and mortality.
Subjects/Keywords: pregnancy complications.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Nusraat, G. (2016). Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
. (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4796
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Nusraat, Gangat. “Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
.” 2016. Thesis, University of Zambia. Accessed February 26, 2021.
http://dspace.unza.zm:8080/xmlui/handle/123456789/4796.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Nusraat, Gangat. “Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
.” 2016. Web. 26 Feb 2021.
Vancouver:
Nusraat G. Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
. [Internet] [Thesis]. University of Zambia; 2016. [cited 2021 Feb 26].
Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Nusraat G. Fetal outcomes in antenatal women admitted with a diagnosis of prolonged latent phase of labour at university teaching hospital Lusaka
. [Thesis]. University of Zambia; 2016. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4796
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Queens University
6.
Redhead, MacKenzie.
The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
.
Degree: Anatomy and Cell Biology, 2015, Queens University
URL: http://hdl.handle.net/1974/13694
► Uterine natural killer (uNK) cells are the most abundant lymphocyte in early human and mouse decidua. UNK cell functions have been deduced by histopathologic comparisons…
(more)
▼ Uterine natural killer (uNK) cells are the most abundant lymphocyte in early human and mouse decidua. UNK cell functions have been deduced by histopathologic comparisons of implantation sites between alymphoid (NK-T-B-), NK cell reconstituted alymphoid (NK+T-B-) and normal NK+T+B+ mice. Circulating (c)NK cells are reported to be absent from C57BL/6 mice genetically ablated for the transcription factor Nfil3 (cNK-T+B+) and these mice experience midgestation Th17 cell-mediated fetal loss when mated by BALB/c males. Recently, tissue resident subsets of NK cells have been described in this mouse.
A histological time-course examination of syngeneic Nfil3-/- male x Nfil3-/- female and allogeneic BALB/c-Tg(UBC-GFP)30Scha/J
male x Nfil3-/- female pregnancy (gestation day; GD 6.5-15.5) was performed to determine the consequences of a maternal cNK-T+B+ phenotype on pregnancy with an Nfil3-/- or Nfil3+/- conceptus. Whole mount immunofluorescence (WM-IF) was used as an additional technique to provide greater insights at midgestation. Nfil3 is a pleiotrophic factor; to examine Nfil3-dependent uNK cell-specific effects, pregnancies in Nfil3-/- bone marrow engrafted alymphoid mice (BME) were studied.
UNK cells were less frequent in Nfil3-/- pregnancies and viability of Nfil3-/- implantation sites (IS) did not differ from wild type (WT) matings. Early gestation pathologies included impaired antimesometrial decidualization (AMD) and delays in lumen closure and embryo development (ED). WM examination revealed an enrichment of CD45+CD11c+ cells at GD 8.5 in Nfil3-/- IS compared to WT. Mid-late gestation placental development, including labyrinth vascular space area and interhemal membrane width, deviated significantly less from WT in allogeneic compared to syngeneic matings. BME and alymphoid placental development was similar to WT. Spiral artery (SA) remodeling did not occur in any experimental mating.
Results of the present investigation suggest Nfil3-independent uNK cells do not promote AMD or GD 8.5 ED and cannot remodel SAs. Nfil3 plays a role in placental tissue layer (specifically labyrinth) development possibly through trophoblast-dependent mechanisms. The absence of Nfil3 may promote recruitment or differentiation of CD45+CD11c+ cells in the early gestation implantation site. Although not an effective model for studying NK-T+B+ pregnancy, the Nfil3-/- mouse deepens the understanding of innate lymphoid cells and their respective subsets.
Subjects/Keywords: Pregnancy
;
NFIL3
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Redhead, M. (2015). The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
. (Thesis). Queens University. Retrieved from http://hdl.handle.net/1974/13694
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Redhead, MacKenzie. “The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
.” 2015. Thesis, Queens University. Accessed February 26, 2021.
http://hdl.handle.net/1974/13694.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Redhead, MacKenzie. “The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
.” 2015. Web. 26 Feb 2021.
Vancouver:
Redhead M. The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
. [Internet] [Thesis]. Queens University; 2015. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/1974/13694.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Redhead M. The Transcription Factor NFIL3 Is Not Required For Uterine Natural Killer Cell Differentiation But Contributes To Placental And Conceptus Development
. [Thesis]. Queens University; 2015. Available from: http://hdl.handle.net/1974/13694
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Nairobi
7.
Kato, Dismas Kituyi.
Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
.
Degree: 2015, University of Nairobi
URL: http://hdl.handle.net/11295/90755
► Retention of students from the beginning of their education to completion at any level is the hallmark and the ultimate goal of any education system…
(more)
▼ Retention of students from the beginning of their education to completion at any
level is the hallmark and the ultimate goal of any education system in any
country. Compared to boys, girls face numerous hurdles in their pursuit of
education that causes unanticipated school interruptions and the likely eventuality
of school dropout; a phenomenon that affects equitable human capital formation.
Specific to the girl child, is the menace of teenage pregnancy and the associated
secondary school dropout that this study sought to address. The study was guided
by human capital theory. The specific objectives were: to establish the extent to
which individual factors influence teenage pregnancy in public day secondary
schools in Kimilili Sub-County, to examine the extent to which home based
factors influence teenage pregnancy in public day secondary schools in Kimilili
Sub-County, to determine the extent to which school factors influence teenage
pregnancy in public day secondary schools in Kimilili Sub-County and to assess
the extent to which teenage pregnancy influence completion rate of girls in public
day secondary schools Kimilili Sub-County. The study deployed descriptive
survey research design. The accessible population was 300 form four girls, 18
Directors of Study and 1 D. o. E. Stratified random sampling was used to come up
with 90 form four girls from 8 schools and 8 Directors of Study while census
sampling was used to select the D.o.E. The study used questionnaires for students
and Directors of Study and an interview schedule was administered on the Sub
County D.o.E. Validity of the instruments was determined by the researcher who
formulated items according to the research objectives. Experts from the
Department of Educational Administration and Planning verified content validity.
The instruments were piloted in two schools that were excluded in the actual
study and test re-test method was used to calculate reliability. A reliability
coefficient of 0.6 was attained and hence accepted as reliable. Data collected was
analyzed using measures of central tendency. Results were then presented using
tables. The study found out that individual sexual behaviour of students, lack of
strict parental supervision and monitoring, home poverty, poor academic
performance at school, and sexual harassment by both boys and teachers exposed
girls to the problem of teenage pregnancy. The study also established that over
40% of the girls‟ dropout cases were due to teenage pregnancy over the four year
cycle in day secondary schools in Kimilili Sub-County. The study recommended
the creation of clear partnerships between public health facilities and schools to
promote effective utilization of YFRHS, sensitization of parents on their roles,
monitoring of poor academic performers at school and legal prosecution of
teachers found harassing school girls.
Subjects/Keywords: Teenage pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kato, D. K. (2015). Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
. (Thesis). University of Nairobi. Retrieved from http://hdl.handle.net/11295/90755
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kato, Dismas Kituyi. “Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
.” 2015. Thesis, University of Nairobi. Accessed February 26, 2021.
http://hdl.handle.net/11295/90755.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kato, Dismas Kituyi. “Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
.” 2015. Web. 26 Feb 2021.
Vancouver:
Kato DK. Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
. [Internet] [Thesis]. University of Nairobi; 2015. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/11295/90755.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kato DK. Influence of teenage pregnancy on completion rates among girls in public day secondary schools in Kimilili Sub-County
. [Thesis]. University of Nairobi; 2015. Available from: http://hdl.handle.net/11295/90755
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia
8.
Chisha, Percival Sume.
Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
.
Degree: 2016, University of Zambia
URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701
► Background: Ectopic pregnancy is defined as a pregnancy outside the uterine cavity and is a life-threatening emergency in the field of obstetrics and gynaecology. It…
(more)
▼ Background: Ectopic pregnancy is defined as a pregnancy outside the uterine cavity and
is a life-threatening emergency in the field of obstetrics and gynaecology. It is a most
common cause of maternal morbidity and mortality in the first trimester of pregnancy. In
resource-constrained settings, where trained specialists are limited in number and
geographic location, outcomes are worse. Diagnosis is frequently missed, partly because
the patient may not be aware that she is pregnant. However, timely diagnosis
accompanied by appropriate management of ectopic pregnancy can alter the clinical
course from death to life. The study aims to determine the epidemiology of ectopic
pregnancies at University Teaching Hospital (UTH).
Methods: A cross sectional study conducted between May, 2014 to November, 2014 in
the Department of Obstetrics and Gynaecology at the University Teaching Hospital,
Lusaka, Zambia. Women treated for ectopic pregnancies were recruited from the
gynaecology ward, interviewed by research assistants and data abstracted from their
medical files.
Results: A total of 90 women with ectopic pregnancies were enrolled representing 0.5%
of early and late pregnancy admissions (total 19,600 pregnant women reviewed between
May 2014 –November, 2014). Over 70% were from high residential areas, 52% had at
least secondary education, and 81.1% were married or co-habiting. Although 27.8% were
HIV positive, 37.8% did not have a known status. Almost half (46.6%) were in their first
or second pregnancy. Though 10% were in the second trimester (13-19weeks) gestation,
most (67.8%) were below 12 weeks and in 22% the gestation was not known. The
commonest risk factors were: more than one sexual partner ever (55.6%) with 10% ever
treated for a sexually transmitted disease. The commonest symptoms were lower
abdominal pain (97.8%) and amaenorrhea (83.3%). Dizziness was reported in 48.9%.
About a quarter (24.4%) were considered in shock on admission and most had abdominal
tenderness (86.7%). Where an ultrasound was done (n=57, 63.3%) this was helpful in
86% of cases (n=49). Haemoperitnem was reported in 59.6%. In 65 cases (72.2%) either
paracentesis or culdocentesis was done and was positive for blood in 49 (75.4%) of cases.
Apart from only one case treated with methotrexate, all other had a laparotomy and 70%
were found ruptured. The commonest sites for the ectopic were infundibulum (33.3%)
and ampulla (28.9%). Salpingectomy was the commonest procedure (84.4%). Over half
(54.3%) had blood loss greater than 500mls. And 44 (48.9%) were transfused. In 34 cases
of those transfused, one or two units were transfused. Four patients (4.4%) were
recovered in a high dependency unit – the rest in an ordinary ward. One patient died (case
fatality of 1.1%).
Conclusion: The series at UTH showed that ectopic pregnancy had a low prevalence and
had a risk factor profile and clinical presentation like that described elsewhere in the
region. Most cases presented with a ruptured ectopic requiring blood transfusion.…
Subjects/Keywords: ectopic pregnancy.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Chisha, P. S. (2016). Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
. (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4701
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Chisha, Percival Sume. “Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
.” 2016. Thesis, University of Zambia. Accessed February 26, 2021.
http://dspace.unza.zm:8080/xmlui/handle/123456789/4701.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Chisha, Percival Sume. “Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
.” 2016. Web. 26 Feb 2021.
Vancouver:
Chisha PS. Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
. [Internet] [Thesis]. University of Zambia; 2016. [cited 2021 Feb 26].
Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Chisha PS. Epidemiology of ectopic pregnancy at the university teaching hospital,Lusaka
. [Thesis]. University of Zambia; 2016. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4701
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

North-West University
9.
Gaoaketse, Violet Keitumetsi.
Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
.
Degree: 2013, North-West University
URL: http://hdl.handle.net/10394/14412
► Learner pregnancy is regarded as a major concern and a serious threat to gender parity in education. Addressing learner pregnancy is not a challenge facing…
(more)
▼ Learner pregnancy is regarded as a major concern and a serious threat to gender
parity in education. Addressing learner pregnancy is not a challenge facing only
Department of Education, it is a battle that requires the active involvement of all
stakeholders that is educators, Non -governmental organisation, Department of
Education, Health and Social Development.
The rate of learner pregnancy in public schools, prompted the Department of
Education to release the policy of Learner Pregnancy Policy which ensures the rights
of pregnant learners to continue with schools. The policy is based on prevention and
management.
This research study investigate how schools implement learner pregnancy policy.
The objectives of the study are:
• To investigate how schools encourage the prevention strategies of learner
pregnancy policy;
• To investigate how schools manage learner pregnancy;
• To identify how Department of Education are involved in monitoring of the
schools in implementing the pregnant learner policy.
The study was conducted in four targeted high schools in the Lichtenburg area
A qualitative approach and quantitative approach was used. Questionnaires and
interviews were used as instruments. A purposeful sampling of 100 educators
and 10 managers was selected. Statistical Package for Social Sciences was
used for data analysis. The Findings of the study revealed that schools are not
doing enough to provide learners with prevention strategies of learner
pregnancy; Even though the policy encourages managers and educators to
support learners who are pregnant, educators and managers still need to
encourage pregnant learners to continue with their education when they are
pregnant in line with the policy. Department of Education does not monitor and
evaluate the effectiveness of the policy regularly in schools.
Recommendation of the study revealed that: Learners must be engaged in extra
mural activities to keep them busy, Educators and managers must help, support
and encourage pregnant learners to continue with their education and that the
Provincial Department of Education must appoint a person at the department to monitor the effectiveness of the policy in schools, to visits schools regularly and
to ensure their compliance.
Subjects/Keywords: Teenage pregnancy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Gaoaketse, V. K. (2013). Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
. (Thesis). North-West University. Retrieved from http://hdl.handle.net/10394/14412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Gaoaketse, Violet Keitumetsi. “Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
.” 2013. Thesis, North-West University. Accessed February 26, 2021.
http://hdl.handle.net/10394/14412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Gaoaketse, Violet Keitumetsi. “Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
.” 2013. Web. 26 Feb 2021.
Vancouver:
Gaoaketse VK. Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
. [Internet] [Thesis]. North-West University; 2013. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/10394/14412.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Gaoaketse VK. Assessing the implementation of learner pregnancy policy in high schools in the Lichtenburg area / Violet Keitumetsi Gaoaketse
. [Thesis]. North-West University; 2013. Available from: http://hdl.handle.net/10394/14412
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of the Western Cape
10.
Johnstone, Muriel.
Teenage mothers’ reflections of their unintended, repeat pregnancies
.
Degree: 2013, University of the Western Cape
URL: http://hdl.handle.net/11394/3574
► Globally, teenage pregnancy remains a disturbing phenomenon which impacts on the lives of teenagers, their families and society as a whole. Numerous attempts at addressing…
(more)
▼ Globally, teenage
pregnancy remains a disturbing phenomenon which impacts on the lives of teenagers, their families and society as a whole. Numerous attempts at addressing the problem have seen a decline in fertility rates but agreement still exists that the incidence of young girls bearing children is unacceptably high. Studies conducted over the years have emphasised both the causes and consequences of teenage births. Many studies too have explored the benefits of preventative strategies. Yet, despite all this, teenage
pregnancy remains a cause for concern with many teenage girls remaining sexually active after a first
pregnancy, and exposing themselves to subsequent pregnancies and births.
This study was focused on teenage girls who had experienced unintended repeat
pregnancies. Through the research a deeper understanding of the meanings that female teenagers ascribe to repeat pregnancies, were sought. A sample group of teenage mothers were allowed to take a step back from their experience of the repeat
pregnancy; to think deeply about the experience, and to reflect on what they had learnt and how it has impacted on their current lives. The researcher employed a qualitative approach with a descriptive, explorative design in order to obtain a rich description of the experiences of teenage mothers who have been through a repeat
pregnancy. The goal of the study was to explore and describe the reflections of these teenage mothers who had experienced unintended, repeat pregnancies. Data was obtained through semi-structured individual interviews where an interview guide was used. The data was analysed according to the
steps outlined by Creswell (2009). Findings were noted and recommendations made. These recommendations are designed for role-players involved with teenagers and youth in general. Emphasis was placed on recommendations to professionals, like educators, healthcare workers and social workers who are at the coalface of dealing with teenagers who engage in sexual activity. Finally, recommendations for further research were made.
Advisors/Committee Members: Jager, M. de (advisor).
Subjects/Keywords: Reflections;
Teenager/Adolescent;
Pregnancy;
Teenage/Adolescent pregnancy;
Repeat pregnancy;
Unintended pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Johnstone, M. (2013). Teenage mothers’ reflections of their unintended, repeat pregnancies
. (Thesis). University of the Western Cape. Retrieved from http://hdl.handle.net/11394/3574
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Johnstone, Muriel. “Teenage mothers’ reflections of their unintended, repeat pregnancies
.” 2013. Thesis, University of the Western Cape. Accessed February 26, 2021.
http://hdl.handle.net/11394/3574.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Johnstone, Muriel. “Teenage mothers’ reflections of their unintended, repeat pregnancies
.” 2013. Web. 26 Feb 2021.
Vancouver:
Johnstone M. Teenage mothers’ reflections of their unintended, repeat pregnancies
. [Internet] [Thesis]. University of the Western Cape; 2013. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/11394/3574.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Johnstone M. Teenage mothers’ reflections of their unintended, repeat pregnancies
. [Thesis]. University of the Western Cape; 2013. Available from: http://hdl.handle.net/11394/3574
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Michigan State University
11.
Palmer, Helen Jean.
Factors affecting hypertriglyceridemia during pregnancy.
Degree: MS, Department of Food Science and Human Nutrition, 1979, Michigan State University
URL: http://etd.lib.msu.edu/islandora/object/etd:42319
Subjects/Keywords: Pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Palmer, H. J. (1979). Factors affecting hypertriglyceridemia during pregnancy. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:42319
Chicago Manual of Style (16th Edition):
Palmer, Helen Jean. “Factors affecting hypertriglyceridemia during pregnancy.” 1979. Masters Thesis, Michigan State University. Accessed February 26, 2021.
http://etd.lib.msu.edu/islandora/object/etd:42319.
MLA Handbook (7th Edition):
Palmer, Helen Jean. “Factors affecting hypertriglyceridemia during pregnancy.” 1979. Web. 26 Feb 2021.
Vancouver:
Palmer HJ. Factors affecting hypertriglyceridemia during pregnancy. [Internet] [Masters thesis]. Michigan State University; 1979. [cited 2021 Feb 26].
Available from: http://etd.lib.msu.edu/islandora/object/etd:42319.
Council of Science Editors:
Palmer HJ. Factors affecting hypertriglyceridemia during pregnancy. [Masters Thesis]. Michigan State University; 1979. Available from: http://etd.lib.msu.edu/islandora/object/etd:42319

Addis Ababa University
12.
Emshaw, Tirfe.
Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
Degree: 2019, Addis Ababa University
URL: http://10.6.20.92/handle/123456789/20909
► Background: Globally every day 830 women die from preventable causes related to pregnancy and childbirth and 99% of maternal deaths occur in developing countries. Young…
(more)
▼ Background: Globally every day 830 women die from preventable causes related to
pregnancy and childbirth and 99% of maternal deaths occur in developing countries. Young people and adolescents face higher risk of complication. Unintended
pregnancy among young people increases risk of maternal morbidity and mortality.
Objectives: The objectives of this study are to estimate the prevalence of unintended
pregnancy among youth in Ethiopia and to explore the factors associated with the unintended
pregnancy.
Methods: We employed mixed methods. The quantitative part applied cross sectional study design using data from Ethiopian Demographic and Health Survey (EDHS) 2016. The dataset was accessed online www.measuredhs.com. The qualitative method applied in- depth interview of purposively selected 15-24 years old female who visited health facilities for antenatal or abortion care service. Quantitative data was analyzed using STATA version 14 software. Descriptive and binary logistical regression analysis techniques were used to estimate the prevalence unintended
pregnancy and identify factors associated with unintended
pregnancy. Qualitative data was analyzed by open code version 4.02 using content analysis method.
Result: Four hundred youths (6.5%) were found to be pregnant from a total of 6,143 (weighted) youths who participated in the 2016 EDHS. Among the pregnant youths 141(35.3%) had no education, 197(49.3%) attended primary school, 372 (93%) were married, 235(58.8%) were unemployed, and 343(85.7%) live in rural area. The prevalence of unintended
pregnancy among pregnant youth was 25%. In-depth interview data analysis showed contraceptive failure, not using any modern contraceptive, low risk prediction, lack of support by family, partner disagreement and desire to continue education were found to be the main reasons for having unintended
pregnancy.
Conclusion and Recommendation: The prevalence of unintended
pregnancy among youth in Ethiopia is high. Effort should focus on empowering women to make them psychological and economic independent to enable them decide about their
pregnancy. Changing the wrong belief and perception on modern contraception in the community is important to improve utilization of those methods by young women.
Advisors/Committee Members: Assegid, Meselech(B.Sc., MPH) (advisor), Seifu, Abiy(B.Sc., MPH) (advisor).
Subjects/Keywords: Unintended pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Emshaw, T. (2019). Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
(Thesis). Addis Ababa University. Retrieved from http://10.6.20.92/handle/123456789/20909
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Emshaw, Tirfe. “Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
” 2019. Thesis, Addis Ababa University. Accessed February 26, 2021.
http://10.6.20.92/handle/123456789/20909.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Emshaw, Tirfe. “Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
” 2019. Web. 26 Feb 2021.
Vancouver:
Emshaw T. Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
[Internet] [Thesis]. Addis Ababa University; 2019. [cited 2021 Feb 26].
Available from: http://10.6.20.92/handle/123456789/20909.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Emshaw T. Assessment of prevalence of unintended pregnancy and understanding the reasons in preventing unintended pregnancy among youth in Ethiopia, 2019.
[Thesis]. Addis Ababa University; 2019. Available from: http://10.6.20.92/handle/123456789/20909
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

McGill University
13.
Philip, Anie.
Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.
Degree: PhD, Department of Physiology, 1986, McGill University
URL: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf
;
https://escholarship.mcgill.ca/concern/theses/z890rw87g
► Sex hormone-binding globulin ( SHBG) is a plasma protein which binds testosterone and estradiol in vitro with high affinity and specificity. There is conflicting evidence…
(more)
▼ Sex hormone-binding globulin ( SHBG) is a plasma protein which binds testosterone and estradiol in vitro with high affinity and specificity. There is conflicting evidence as to the role of SHBG in the transport of estradiol under in vive conditions. Studies describing the distribution of estradiol and testosterone into SHBG-bound, albumin-bound and unbound fractions were carried out using equilibrium dialysis of whole serum at 37°C under isosmotic conditions. The results showed that SHBG was an important binder of estradiol in both pregnant and non-pregnant women, but of minimal significance in men and in newborn infants. Testosterone was significantly bound to SHBG under all circumstances. In order to characterize previously unrecognized substances that may bind to SHBG in pregnancy, maternal serum was fractionated on Sephadex LH-20. A substantial part of the SHBG-bound material eluted as 4 major peaks which did not correspond to any of the steroids thought to bind to SHBG. Comparison of levels in maternal, fetal and placental compartments suggested that all 4 peaks were of placental origin. Three were identified as 5 a-pregnane-3, 20-dione, progesterone and 2-methoxyestrone on the basis of elution pattern on Sephadex LH-20, binding characteristics, high performance liquid chromatography, and gas chromatography-mass spectrometry. The fourth peak was identified as a 19-nor androgen, i.e. 17B-hydroxy-1, 5-estradiene-3-one, on the basis of similar kinds of evidence and in addition, solubility characteristics and ultra-violet absorption spectrum. Since its level fell in association with premature and term labour, its decrease may be involved in the initiation of labour.
La globuline liant les hormones sexuelles (Sex Hormone Binding Globulin, SHBG) est une protéine plasmatique qui se lie spécifiquement à la testostérone et a l'estradiol in vitro. Cette liaison est de haute affinité. Toutefois, le rôle de la SHBG dans le transport de l'estradiol in vivo est mal connu. Nous avons procédé à l'étude des fractions d'estradiol et de testostérone liées à la SHBG ou à l'albumine ou simplement libres en effectuant une dialyse a l'équilibre du sérum à 37°C en conditions isosmotiques. Les résultats ont démontré que la SHBG constitue un facteur important dans la liaison de l'estradiol sérique chez la femme gravide et non gravide. Toutefois, la liaison à l'estradiol s'est avérée minime chez l'homme et chez le nouveau-né. La testostérone était liée à la SHBG en quantité significative dans toutes les conditions que nous avons étudiées. Afin de procéder à la caractérisation de substances liées à la SHBG durant la grossesse et jusqu'à présent non identifiés, le sérum maternel a été fractionné sur Sephadex LH-20. Une proportion importante du matériel lie à la SHBG éluait en 4 principaux pies lesquels ne correspondaient à aucune des stéroïdes que l'on pense se lient à la SHBG. La comparaison des niveaux des quatres pies dans les compartiments maternel, fétal et placentaire suggérait que ces derniers étaient d'origine placentaire. Trois…
Advisors/Committee Members: Pearson, Beverley E..
Subjects/Keywords: Pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Philip, A. (1986). Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. (Doctoral Dissertation). McGill University. Retrieved from https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g
Chicago Manual of Style (16th Edition):
Philip, Anie. “Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.” 1986. Doctoral Dissertation, McGill University. Accessed February 26, 2021.
https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g.
MLA Handbook (7th Edition):
Philip, Anie. “Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy.” 1986. Web. 26 Feb 2021.
Vancouver:
Philip A. Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. [Internet] [Doctoral dissertation]. McGill University; 1986. [cited 2021 Feb 26].
Available from: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g.
Council of Science Editors:
Philip A. Steroid Binding to Sex Hormone-Binding Globulin: Studies on Relative Binding of Estradiol and Testosterone, and Characterization of Certain Previously Unrecognized Ligands in Pregnancy. [Doctoral Dissertation]. McGill University; 1986. Available from: https://escholarship.mcgill.ca/downloads/1c18dj061.pdf ; https://escholarship.mcgill.ca/concern/theses/z890rw87g

University of Manchester
14.
Mcdermott, Siofra.
Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function.
Degree: 2015, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718
► Since the introduction of coffee to Europe in the early 17th century its popularity has steadily increased and, water apart, is the most widely consumed…
(more)
▼ Since the introduction of coffee to Europe in the
early 17th century its popularity has steadily increased and, water
apart, is the most widely consumed beverage globally. Being derived
from a plant, a cup of coffee represents a complex mixture of
naturally occurring chemicals such as caffeine, coffee oils and
chlorogenic acid. As the popularity for coffee has grown so too has
the interest surrounding its possible biological and
pharmacological effects. A small number of studies suggest
potential risks and benefits associated with coffee consumption in
pregnancy; however these have yet to provide definitive
conclusions. Furthermore government advice does not directly
address coffee intake during
pregnancy and there is no information
regarding womens’ and midwives’ views and opinions on this
increasingly important issue. This was a mixed-method research
study, with both a qualitative and quantitative components.
Firstly, I aimed to gain insight into womens’ and midwives’ views
and opinions on coffee consumption during
pregnancy. Informed
written consent was obtained from women attending the hospital for
their antenatal care. These women were of varying gestational age,
ethnic background, socioeconomic status and age. Informed written
consent was also obtained from midwives from varying disciplines
and experience levels; those from academia, research and practicing
midwives included. I recruited twenty participants in each group.
Information and perspectives were gathered through semi-structured
face-to-face or telephone interviews. Interviews were analysed with
the Framework method of analysis. The second quantitative arm of my
study investigated the effect of specific coffee chemicals on
placental and myometrial vascular function. Human chorionic plate
arteries, isolated from placental biopsies, and maternal myometrial
arteries isolated from myometrial biopsies, were assessed by wire
myography. Contraction and relaxation were determined to
incremental doses of caffeic acid, chlorogenic acid and caffeine.
The antioxidative properties of these chemicals were also assessed
in response to application of reactive oxygen species.My findings
indicated that women and midwives’ were unsure of the information
surrounding coffee consumption. Pregnant women and midwives’
discussed the provision of information, sources of information and
supplementing information. Findings also indicated that the
relationship between health care professional and pregnant women
can influence willingness to accept information and womens’ level
of
pregnancy stress. My laboratory studies indicated that the
active coffee chemicals did not significantly impact on placental
or myometrial arterial function. The chemicals investigated did not
elicit any significant protective antioxidative effects. Combining
methods allowed for a more comprehensive primary study to be
completed. My literature search indicated that there was a clear
gap in the knowledge surrounding coffee and its consumption during
pregnancy. There is a clear lack of evidence-based…
Advisors/Committee Members: LAVENDER, TINA T, Wareing, Mark, Lavender, Tina.
Subjects/Keywords: Coffee; Pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mcdermott, S. (2015). Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718
Chicago Manual of Style (16th Edition):
Mcdermott, Siofra. “Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function.” 2015. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718.
MLA Handbook (7th Edition):
Mcdermott, Siofra. “Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function.” 2015. Web. 26 Feb 2021.
Vancouver:
Mcdermott S. Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function. [Internet] [Doctoral dissertation]. University of Manchester; 2015. [cited 2021 Feb 26].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718.
Council of Science Editors:
Mcdermott S. Coffee and Pregnancy: Attitudes, Consumption and Maternal
Vascular Function. [Doctoral Dissertation]. University of Manchester; 2015. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:277718

University of British Columbia
15.
Powell, Martha Bauder.
Ethnography of pregnancy in our culture.
Degree: MA- MA, Sociology, 1972, University of British Columbia
URL: http://hdl.handle.net/2429/33438
► The essay describes ethnographically some of the special experiences of married women during pregnancy. Data were collected among middle class women in Vancouver, British Columbia,…
(more)
▼ The essay describes ethnographically some of the special experiences of married women during pregnancy. Data were collected among middle class women in Vancouver, British Columbia, by means of observation, interviews, and a questionnaire.
.
Material relates to 1) the social relationships of pregnant women to other people, 2) some of the social customs practiced during pregnancy, 3) the social readjustments which occur as a result of pregnancy, and 4) preconceived notions about pregnancy in our culture.
The essay concludes that during pregnancy, certain kinds of communication with other persons (particularly kin, good friends, and medical personnel) provide a means by which women learn to orient themselves to the physical and social realities of pregnancy and motherhood. This communication entails the mutual exchange of knowledge and feelings, and the content and function of these exchanges are discussed
Subjects/Keywords: Pregnancy
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APA (6th Edition):
Powell, M. B. (1972). Ethnography of pregnancy in our culture. (Masters Thesis). University of British Columbia. Retrieved from http://hdl.handle.net/2429/33438
Chicago Manual of Style (16th Edition):
Powell, Martha Bauder. “Ethnography of pregnancy in our culture.” 1972. Masters Thesis, University of British Columbia. Accessed February 26, 2021.
http://hdl.handle.net/2429/33438.
MLA Handbook (7th Edition):
Powell, Martha Bauder. “Ethnography of pregnancy in our culture.” 1972. Web. 26 Feb 2021.
Vancouver:
Powell MB. Ethnography of pregnancy in our culture. [Internet] [Masters thesis]. University of British Columbia; 1972. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/2429/33438.
Council of Science Editors:
Powell MB. Ethnography of pregnancy in our culture. [Masters Thesis]. University of British Columbia; 1972. Available from: http://hdl.handle.net/2429/33438

Michigan State University
16.
Does, Richard Bowditch.
Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.
Degree: MA, Dept. of Psychology, 1965, Michigan State University
URL: http://etd.lib.msu.edu/islandora/object/etd:15764
Subjects/Keywords: Pregnancy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Does, R. B. (1965). Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. (Masters Thesis). Michigan State University. Retrieved from http://etd.lib.msu.edu/islandora/object/etd:15764
Chicago Manual of Style (16th Edition):
Does, Richard Bowditch. “Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.” 1965. Masters Thesis, Michigan State University. Accessed February 26, 2021.
http://etd.lib.msu.edu/islandora/object/etd:15764.
MLA Handbook (7th Edition):
Does, Richard Bowditch. “Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing.” 1965. Web. 26 Feb 2021.
Vancouver:
Does RB. Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. [Internet] [Masters thesis]. Michigan State University; 1965. [cited 2021 Feb 26].
Available from: http://etd.lib.msu.edu/islandora/object/etd:15764.
Council of Science Editors:
Does RB. Acceptance and rejection in attitudes toward pregnancy, child bearing and child rearing. [Masters Thesis]. Michigan State University; 1965. Available from: http://etd.lib.msu.edu/islandora/object/etd:15764

University of Aberdeen
17.
Lamont, Kathleen A.
Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.
Degree: PhD, 2019, University of Aberdeen
URL: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941
;
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011
► Background: Previous meta-analyses assessing risk of recurrent stillbirth were limited by clinical and statistical heterogeneity. This study aimed to address these limitations using individual participant…
(more)
▼ Background: Previous meta-analyses assessing risk of recurrent stillbirth were limited by clinical and statistical heterogeneity. This study aimed to address these limitations using individual participant data (IPD). Methods: An online survey of perinatal databases in high-income countries identified potential datasets for inclusion in the IPD meta-analysis. IPD from Scotland, Finland and Malta were analysed to calculate risk of stillbirth in a second or subsequent pregnancy using logistic regression and survival analysis. The chance of having another stillbirth if previous stillbirth was explained or unexplained was also investigated. Results: The pooled dataset included 1,068,258 women, 3,529 with a stillbirth and 1,064,729 with a livebirth in a second pregnancy. Women with a stillbirth in a second pregnancy had increased odds of stillbirth in a previous pregnancy, adjusted OR 3.41, 95% CI (2.72 TO 4.28). Increasing maternal age, overweight and obesity, having no partner, lower social class, smoking during pregnancy and short (1 year or less) and long (≥6 years) interpregnancy intervals were independent risk factors for stillbirth in a second pregnancy as were placental abruption, diabetes, threatened miscarriage, intra-uterine growth restriction and cord or hand prolapse. Compared to women who had a livebirth in a first pregnancy, women who had a stillbirth were more likely to have a subsequent stillbirth, adjusted HR 2.25, 95% CI (1.86 to 2.72). Women who were younger than 20, smoked, deprived, had no partner, had diabetes mellitus, preeclampsia, placental abruption or growth restricted foetus in their first pregnancy were also more likely to have a subsequent stillbirth. There was no difference in the risk of subsequent stillbirth whether the previous stillbirth was explained or unexplained (OR .0.92, 95% CI 0.64 to 1.32). Conclusion: Women with a stillbirth in a first pregnancy have a higher risk of recurrence in a subsequent pregnancy even when the cause is unknown.
Subjects/Keywords: Pregnancy; Stillbirth
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Lamont, K. A. (2019). Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. (Doctoral Dissertation). University of Aberdeen. Retrieved from https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011
Chicago Manual of Style (16th Edition):
Lamont, Kathleen A. “Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.” 2019. Doctoral Dissertation, University of Aberdeen. Accessed February 26, 2021.
https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011.
MLA Handbook (7th Edition):
Lamont, Kathleen A. “Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis.” 2019. Web. 26 Feb 2021.
Vancouver:
Lamont KA. Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. [Internet] [Doctoral dissertation]. University of Aberdeen; 2019. [cited 2021 Feb 26].
Available from: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011.
Council of Science Editors:
Lamont KA. Risk of recurrent stillbirth : an Individual Participant Data (IPD) meta-analysis. [Doctoral Dissertation]. University of Aberdeen; 2019. Available from: https://abdn.alma.exlibrisgroup.com/view/delivery/44ABE_INST/12152646070005941 ; https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.774011

University of Zambia
18.
Kakonkanya-Kambole, Gertrude Namunji.
Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
.
Degree: 2011, University of Zambia
URL: http://hdl.handle.net/123456789/564
► Malaria infection during pregnancy is a major public health problem in the tropical and subtropical regions of the world. Pregnant women in developing countries are…
(more)
▼ Malaria infection during pregnancy is a major public health problem in the tropical and subtropical regions of the world. Pregnant women in developing countries are the worst affected. Malaria in pregnancy has serious consequences both to the mother and her baby. It leads to abortion, prematurity, low birth weight, foetal death, neonatal death, severe anaemia and maternal death. The current stratagem in the prevention of malaria in pregnancy includes use of ITNs and IPT/SP. The purpose of this study was to determine the effectiveness of IPT/SP in clearing placental malaria parasites in pregnant women in Kafue District.
A case-control study was conducted in two health centres in Kafue District. The cases were the postnatal women whose placentas had malaria parasites. The controls comprised of postnatal women whose placentas had no malaria parasites.
The study was conducted in two health centres in Kafue District. Data was analyzed using SPSS software. Chi-Squared [x²], Fisher’s exact test and Odds Ratio (OR) were used. Multivariate logistic regression analysis was used to control for confounding factors. Statistical significance was achieved if p<0.05.
Totals of 25 cases and 146 controls were enrolled into the study. Compared to the age at which the woman started attending ANC [booking] of above 20 weeks, those who started at gestational age of 12-20 weeks were 49% [p=0.002] less likely to be cases. Compared to the gestational age when the woman had her last dose of IPT of more than 36 weeks, those who had the last dose at less than 36 weeks of gestational period/age were 4.46 [p=0.001] times more likely to be cases. Compared to HIV negative women, those who were positive were 1.73 [p=0.014] times more likely to be cases.In conclusion, the study revealed that the effectiveness of IPT/SP in clearance of placental malaria parasites in pregnancy in Kafue District is affected by three factors. These include timing for antenatal booking, frequency of antenatal visits as well as the HIV status of the antenatal woman.
Subjects/Keywords: Sulphadoxine-Pyrimethamine-Pregnancy;
Malaria Parasites-Pregnancy
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kakonkanya-Kambole, G. N. (2011). Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
. (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/564
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kakonkanya-Kambole, Gertrude Namunji. “Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
.” 2011. Thesis, University of Zambia. Accessed February 26, 2021.
http://hdl.handle.net/123456789/564.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kakonkanya-Kambole, Gertrude Namunji. “Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
.” 2011. Web. 26 Feb 2021.
Vancouver:
Kakonkanya-Kambole GN. Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
. [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/123456789/564.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kakonkanya-Kambole GN. Effectiveness of intermittent Preventive Treatment of Full Course Of Sulphadoxine-Pyrimethamine in Clearance of Placenta Malaria Parasites In Pregnance in Kafue District
. [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/564
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia
19.
Katayamoyo, Patrick.
Determinants of Teenage Pregnancy in Lusaka District
.
Degree: 2011, University of Zambia
URL: http://hdl.handle.net/123456789/752
► A pregnant teenager who drops out of school has her child predisposed to live in abject poverty as she joins the poverty cycle. Society pays…
(more)
▼ A pregnant teenager who drops out of school has her child predisposed to live in abject poverty as she joins the poverty cycle. Society pays a heavy price for children who are likely to lack proper parenting, economic security and at high risk of behavioral problems and vices such as crime, substance abuse and prostitution. Additionally there are serious and sometimes irreversible effects on the mother such as the emotional, psychological and gynaecological complications. The burden of reproductive health problems falls largely on female adolescents. Maternity registry statistics specifically reveal significantly high numbers of teenagers passing through these centers. This was a major thrust of this study, which intended to determine the predisposing factors to teenage pregnancy in order to add to the body of knowledge on the subject of teenage pregnancy and make necessary recommendations based on evidence.
This research was a case control study. The study population were female teenagers (13 to 19 years old) attending clinic at centers where antenatal services are available. The sample populations were two groups of female teenagers. One group constituted cases comprising pregnant teenagers attending antenatal clinic and another group constituted controls comprising female non-pregnant teenagers attending same clinic for any other ailments (with no reported history of pregnancy or abortion). Selection of sites was purposive of four clinics with the highest teenage delivery rates in Lusaka as well as University Teaching Hospital (UTH). Sample size was determined through an initial pilot study. Data was collected using a structured questionnaire through direct (one to one) interviews. Analysis of data resulted in testing the association of the various exposure factors i.e. socio-demographic, contraception, tradition and culture and illicit sex.
The results on multivariate backward logistics regression indicated the following: teenagers below 16 years were 70% less likely to get pregnant compared to those above, singles were 60% less likely to be pregnant compared to those who are married, while participants with breadwinners who were not in gainful employment were two times more likely to get pregnant. Parental/guardian reprimand was shown to have a deterrent effect on teenage pregnancy. Lack of knowledge on female physiology or hormones was shown to predispose to teenage pregnancy by three times whereas lack of knowledge on condoms had similar effect by twofold. Shyness to access contraceptives by teenagers increased chances of pregnancy by fifty percent.
Subjects/Keywords: Pregnancy;
Pregnant School Girls;
Teenage Pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Katayamoyo, P. (2011). Determinants of Teenage Pregnancy in Lusaka District
. (Thesis). University of Zambia. Retrieved from http://hdl.handle.net/123456789/752
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Katayamoyo, Patrick. “Determinants of Teenage Pregnancy in Lusaka District
.” 2011. Thesis, University of Zambia. Accessed February 26, 2021.
http://hdl.handle.net/123456789/752.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Katayamoyo, Patrick. “Determinants of Teenage Pregnancy in Lusaka District
.” 2011. Web. 26 Feb 2021.
Vancouver:
Katayamoyo P. Determinants of Teenage Pregnancy in Lusaka District
. [Internet] [Thesis]. University of Zambia; 2011. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/123456789/752.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Katayamoyo P. Determinants of Teenage Pregnancy in Lusaka District
. [Thesis]. University of Zambia; 2011. Available from: http://hdl.handle.net/123456789/752
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Zambia
20.
Kaluba, Longa.
Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
.
Degree: 2015, University of Zambia
URL: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310
► Background: Hypertensive disease in pregnancy continues to be one of the leading cause of maternal death. Pregnancy induced hypertension (PIH) is said to be accompanied…
(more)
▼ Background: Hypertensive disease in pregnancy continues to be one of the leading cause of maternal death. Pregnancy induced hypertension (PIH) is said to be accompanied by several cardiovascular pathophysiological changes including increases in arterial stiffness. Pulse wave velocity (PWV) is the method for measuring arterial stiffness. Both the pulse wave form and the velocity are said to change in PIH. However, studies documenting these characteristics of PWV have mainly been in the Caucasian population.
Aims & Objectives: To establish the characteristics of PWV in normotensive and hypertensive pregnant women at the UTH in Lusaka, Zambia.
Methodology: This cross-sectional study comprised of 34 systemically selected pregnant women between the ages 18-45 years old who met the criteria. A structured interview was used to collect socio demographic data. Participants’ weights and heights were then measured. After a 15 minute rest, peripheral systolic and diastolic BP were measured using an Omron M6 comfort automatic BP monitor. The PWV measurement involved applying non-invasive piezoelectric sensors over the skin after palpating for the carotid artery on the neck and the radial artery on the wrist (carotid-radial segment C-R PWV); and for the carotid-femoral segment (C-F PWV) palpation was donefor the carotid artery on the neck and the femoral artery on the inner thigh. Using IBM® SPSS® version 20.0, analyses included: kruskal-wallis, mann- whitney tests and spearman correlation tests. A 95% confidence interval (CI) and P-value of < 0.05 were set.
Results: Quality recordings were obtained from C-R PWV process (p=0.041) between normotensive and hypertensive participants. There were significant increase in AP indicating an increase in pressure difference from the systolic shoulder to its peak (p=0.046). There is also a significant increase in Aix indicating an increase in arterial stiffness (p=0.031). This is further supported by a significant difference in PWV. Results from the C-F procedure experienced severe anatomical influences of the pregnant uterus and should therefore be ignored.
Conclusion: Distinct differences were seen in the waveform and PWV amongst individuals with PIH. This supports the vascular changes said to take place in PIH. Thus, PWV can be used as a measure for arterial stiffness and in the screening of PIH and possible treatment
Subjects/Keywords: Hypertension in pregnancy;
Pregnancy Complications, Cardiovascular
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kaluba, L. (2015). Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
. (Thesis). University of Zambia. Retrieved from http://dspace.unza.zm:8080/xmlui/handle/123456789/4310
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kaluba, Longa. “Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
.” 2015. Thesis, University of Zambia. Accessed February 26, 2021.
http://dspace.unza.zm:8080/xmlui/handle/123456789/4310.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kaluba, Longa. “Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
.” 2015. Web. 26 Feb 2021.
Vancouver:
Kaluba L. Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
. [Internet] [Thesis]. University of Zambia; 2015. [cited 2021 Feb 26].
Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kaluba L. Pulse wave velocity in normotensive and hypertensive pregnant women at University Teaching Hospital (UTH), Lusaka, Zambia
. [Thesis]. University of Zambia; 2015. Available from: http://dspace.unza.zm:8080/xmlui/handle/123456789/4310
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Hawaii – Manoa
21.
Elia, Jennifer.
An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.
Degree: 2017, University of Hawaii – Manoa
URL: http://hdl.handle.net/10125/51039
► D.P.H. University of Hawaii at Manoa 2015.
About half of all pregnancies in the United States are unintended (mistimed or unwanted), and this figure has…
(more)
▼ D.P.H. University of Hawaii at Manoa 2015.
About half of all pregnancies in the United States are unintended (mistimed or unwanted), and this figure has held steady for decades despite recognition as a public health priority and efforts to reduce it. Unintended pregnancy has been associated with negative health and social outcomes for mother and child. Hawai‘i has the second highest unintended pregnancy rate in the U.S., and Native Hawaiians appear to have the highest rates of unintended pregnancy among the state’s major ethnic groups.
The purpose of this dissertation was to examine unintended pregnancy in Hawai‘i, with a particular focus on Native Hawaiians, in terms of how different groups are affected (disparities), how it is assessed (measurement), and how it is conceptualized (meanings). The first of three studies used data from the Hawai‘i Pregnancy Risk Assessment Monitoring System to examine disparities by race/ethnicity and other maternal characteristics in: pregnancy intention; trying to get pregnant; discordant responses for intention and trying; contraceptive use before pregnancy; and “didn’t mind” pregnancy as a reason for contraceptive non-use. The second study examined three measures of pregnancy intention – the London Measure of Unplanned Pregnancy (LMUP), National Survey of Family Growth (NSFG) intention categories, and “trying” to get pregnant – in relation to demographic characteristics and pregnancy outcome (prenatal care vs. abortion) through a survey of pregnant women in Honolulu. With eight focus groups of Native Hawaiian women and men, the third study qualitatively described factors related to pregnancy planning and decision-making within this community.
Findings from these three studies speak to the complexity of pregnancy intention and its importance to public health. Many women in Hawai‘i became pregnant when they were not intending, trying, and/or wanting to get pregnant. Furthermore, a substantial proportion of women reported ambivalence towards their pregnancies and did not use contraception despite being “at risk” for unintended pregnancy. Disparities by race/ethnicity and other demographic characteristics were significant in bivariate and multivariate analyses. Cultural factors and social norms may influence the perception and impact of unintended pregnancy among Native Hawaiians. Suggestions for further quantitative and qualitative research and other implications are described.
Subjects/Keywords: Native Hawaiian; unintended pregnancy; pregnancy ambivalence; disparities
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Elia, J. (2017). An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. (Thesis). University of Hawaii – Manoa. Retrieved from http://hdl.handle.net/10125/51039
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Elia, Jennifer. “An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.” 2017. Thesis, University of Hawaii – Manoa. Accessed February 26, 2021.
http://hdl.handle.net/10125/51039.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Elia, Jennifer. “An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians.” 2017. Web. 26 Feb 2021.
Vancouver:
Elia J. An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. [Internet] [Thesis]. University of Hawaii – Manoa; 2017. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/10125/51039.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Elia J. An Investigation of Pregnancy Intention Disparities, Measurement, and Meanings in Hawaii and Among Native Hawaiians. [Thesis]. University of Hawaii – Manoa; 2017. Available from: http://hdl.handle.net/10125/51039
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Virginia Tech
22.
Labrum, Mandaran Lynn.
Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.
Degree: MS, Human Development, 2014, Virginia Tech
URL: http://hdl.handle.net/10919/64196
► This research explores the influence of pregnancy loss and coping strategies employed while connecting to the fetus in a subsequent pregnancy following a late term…
(more)
▼ This research explores the influence of
pregnancy loss and coping strategies employed while connecting to the fetus in a subsequent
pregnancy following a late term loss. Nine participants were interviewed using a qualitative, phenomenological methodology to determine participant's experience. Four themes emerged within the data: (1) support network – participants acknowledged who was there for them and who was not, (2) emotional ups and downs – participants reported the emotional ups and downs from loss to the subsequent
pregnancy to delivery and after birth, and how they connected during this process (3) coping – participants describe coping strategies used throughout their experience, and (4) moving forward – participants reported their process of finding their new normal and how this event changed their perspective on life. Limitations, future research and clinical implications were all identified and discussed.
Advisors/Committee Members: Huebner, Angela J. (committeechair), Wittenborn, Andrea K. (committee member), Falconier, Mariana (committee member).
Subjects/Keywords: pregnancy loss; subsequent pregnancy; coping; connection; attachment
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Labrum, M. L. (2014). Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/64196
Chicago Manual of Style (16th Edition):
Labrum, Mandaran Lynn. “Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.” 2014. Masters Thesis, Virginia Tech. Accessed February 26, 2021.
http://hdl.handle.net/10919/64196.
MLA Handbook (7th Edition):
Labrum, Mandaran Lynn. “Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy.” 2014. Web. 26 Feb 2021.
Vancouver:
Labrum ML. Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. [Internet] [Masters thesis]. Virginia Tech; 2014. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/10919/64196.
Council of Science Editors:
Labrum ML. Hesitantly Happy: The Influence of a Late Term Pregnancy Loss during the Subsequent Pregnancy. [Masters Thesis]. Virginia Tech; 2014. Available from: http://hdl.handle.net/10919/64196

Drexel University
23.
Evans, Amy N.
Social Problem Solving and Psychological Distress among Pregnant Women.
Degree: 2013, Drexel University
URL: http://hdl.handle.net/1860/idea:6547
► Animal and human studies have provided evidence that psychological distress during pregnancy may adversely affect the physical and psychological health of the child and mother.…
(more)
▼ Animal and human studies have provided evidence that psychological distress during pregnancy may adversely affect the physical and psychological health of the child and mother. Given this evidence, it is important to learn about the ways in which women cope with stressors during pregnancy. Social problem-solving is the cognitive-behavioral process whereby an individual copes with stressful problems. As such, the purpose of this study was to determine if social problem-solving statistically predicted psychological distress (i.e., depressive and anxious symptomatology) during pregnancy. It was hypothesized that social problem-solving would statistically predict psychological distress above and beyond demographic variables, stressful life events, and pregnancy related-stressors. Additionally, it was believed that negative problem orientation would be the most predictive. Pregnant women (n = 31; 58.1% white, 16.1% black, 12.9% Latina, 9.7% Asian, and 3.2% other/multiracial; mean age = 30.43 years, SD = 4.99; mean gestational age = 30.23 weeks, SD = 9.18) seeking prenatal care from two university-based obstetric and gynecologic offices in Philadelphia, Pennsylvania were recruited to fill out a series of self-report questionnaires, including the LES, PES, EPDS, PRAQ-R, and SPSI-R. Hierarchical multiple regressions demonstrated that social problem-solving did not statistically predict psychological distress among pregnant women (depression: R2 = 0.47, F(5, 25) = 1.41, p = .25; anxiety: R2 = 0.22, F(5, 24) = 0.58, p = .72). Additional research is needed to determine if social problem-solving predicts psychological distress among pregnant women.
Keywords: pregnancy, anxiety, depression, psychological distress, social problem solving
M.S., Psychology – Drexel University, 2013
Advisors/Committee Members: Nezu, Arthur M..
Subjects/Keywords: Psychology; Pregnancy – Psychological aspects; Pregnancy – Social aspects
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
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APA (6th Edition):
Evans, A. N. (2013). Social Problem Solving and Psychological Distress among Pregnant Women. (Thesis). Drexel University. Retrieved from http://hdl.handle.net/1860/idea:6547
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Evans, Amy N. “Social Problem Solving and Psychological Distress among Pregnant Women.” 2013. Thesis, Drexel University. Accessed February 26, 2021.
http://hdl.handle.net/1860/idea:6547.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Evans, Amy N. “Social Problem Solving and Psychological Distress among Pregnant Women.” 2013. Web. 26 Feb 2021.
Vancouver:
Evans AN. Social Problem Solving and Psychological Distress among Pregnant Women. [Internet] [Thesis]. Drexel University; 2013. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/1860/idea:6547.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Evans AN. Social Problem Solving and Psychological Distress among Pregnant Women. [Thesis]. Drexel University; 2013. Available from: http://hdl.handle.net/1860/idea:6547
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Alberta
24.
Merchant, Neelam.
Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda.
Degree: MSin Global Health, Department of Public Health Sciences, 2010, University of Alberta
URL: https://era.library.ualberta.ca/files/fq977v02q
► The focus of this study is to understand why, despite high uptake of antenatal care, women in Uganda continue to deliver without skilled birth attendants.…
(more)
▼ The focus of this study is to understand why, despite
high uptake of antenatal care, women in Uganda continue to deliver
without skilled birth attendants. A critical gap in our knowledge
is an understanding of the decisions women make during pregnancy
and childbirth that determine the services they seek. Using a
focused ethnography, we explored cultural knowledge and perceptions
related to pregnancy and childbirth in Kabarole district.
Interviews and focus group discussions were conducted with women
that had recently given birth, their husbands/partners, biomedical
and traditional health workers, and older women. HIV was identified
as an important reason for seeking antenatal care. Other services
used during pregnancy, biomedical and traditional, were accessed
based on a complex array of beliefs and advice given to women.
Thaddeus and Maine’s Three Delays Model provided a framework for
analysis of barriers to skilled attendance at birth, which include
distance, support from partners, and quality of health
services.
Subjects/Keywords: childbirth; Uganda; pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Merchant, N. (2010). Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/fq977v02q
Chicago Manual of Style (16th Edition):
Merchant, Neelam. “Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda.” 2010. Masters Thesis, University of Alberta. Accessed February 26, 2021.
https://era.library.ualberta.ca/files/fq977v02q.
MLA Handbook (7th Edition):
Merchant, Neelam. “Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda.” 2010. Web. 26 Feb 2021.
Vancouver:
Merchant N. Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda. [Internet] [Masters thesis]. University of Alberta; 2010. [cited 2021 Feb 26].
Available from: https://era.library.ualberta.ca/files/fq977v02q.
Council of Science Editors:
Merchant N. Decision-making related to pregnancy and childbirth in
Kabarole district, western Uganda. [Masters Thesis]. University of Alberta; 2010. Available from: https://era.library.ualberta.ca/files/fq977v02q

University of Alberta
25.
Dolson, Kirsti.
Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy.
Degree: MA, Faculty of Physical Education and
Recreation, 2011, University of Alberta
URL: https://era.library.ualberta.ca/files/vx021f40t
► The purpose of this study was to determine how two elite female marathon runners used narrative to describe their lived bodily experiences during pregnancy. Information…
(more)
▼ The purpose of this study was to determine how two
elite female marathon runners used narrative to describe their
lived bodily experiences during pregnancy. Information for the
analysis of this phenomenon was derived from two elite runners’
personal narratives obtained from their internet dairies (blogs).
This study employed phenomenology as a form of inquiry and used a
paradigmatic analysis of narratives (Polkinghorne, 1995) to capture
the essence of the runners’ experiences with pregnancy. This study
found that the elite runners wrote about their pregnancies as
something both public and medical. They wrote about their unborn
children as distinct entities and continued to write about their
elite running bodies, despite pregnancy. This study concluded that
the runners had identity struggles as they shifted from being elite
runners to mothers, all while attempting to balance the social
expectations of sport and motherhood.
Subjects/Keywords: pregnancy; narratives; runners
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Dolson, K. (2011). Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy. (Masters Thesis). University of Alberta. Retrieved from https://era.library.ualberta.ca/files/vx021f40t
Chicago Manual of Style (16th Edition):
Dolson, Kirsti. “Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy.” 2011. Masters Thesis, University of Alberta. Accessed February 26, 2021.
https://era.library.ualberta.ca/files/vx021f40t.
MLA Handbook (7th Edition):
Dolson, Kirsti. “Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy.” 2011. Web. 26 Feb 2021.
Vancouver:
Dolson K. Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy. [Internet] [Masters thesis]. University of Alberta; 2011. [cited 2021 Feb 26].
Available from: https://era.library.ualberta.ca/files/vx021f40t.
Council of Science Editors:
Dolson K. Narratives of Elite Runners: descriptions of their bodily
experiences during pregnancy. [Masters Thesis]. University of Alberta; 2011. Available from: https://era.library.ualberta.ca/files/vx021f40t
26.
阿南, あゆみ.
Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.
Degree: 博士(看護学), 2013, Kyushu University / 九州大学
URL: http://hdl.handle.net/2324/21736
;
http://dx.doi.org/10.15017/21736
► This study aimed to investigate the effects of working during gestation on pregnant women by evaluating their mental and physical stress. The subjects were 62…
(more)
▼ This study aimed to investigate the effects of working during gestation on pregnant women by evaluating their mental and physical stress. The subjects were 62 women during natural
pregnancy with a singleton who were not in a state of illness. The survey was conducted by a Questionnaire to clarify their general background, daily activities, working status, mental stress (GHQ28) and measurement of antioxidant capacity (Potential Anti-Oxidant (PAO)) and oxidative stress urinary 8-hydroxydeoxy guanosine (8-OHdG) in early (12-16w) and late (32-36w)
pregnancy. Of the 62 females (primigravida:23, multigravida:39), 41(66.1%) worked in early
pregnancy and 17 (27.4 %) continued to work in late
pregnancy, while the other, i.e. 24, discontinued working. Eight took maternal leave of absence and 16 resigned their jobs during the gestation period. The total GHQ28 scores fell significantly in late
pregnancy compared with early
pregnancy, mainly caused by the relief of Somatic Symptoms. In addition, urinary 8-OHdG lowered significantly in late
pregnancy whereas PAO rose significantly. The reduction of physical stress was recognized in late
pregnancy. The urinary 8-OHdG of working pregnant women was lower than non-working pregnant women in early
pregnancy. The PAO levels were not changed by working status. GHQ28, PAO and urinary 8-OHdG were not significantly related with life activities, such as going up/down, sleep, house-hold work and so on. Mental and physical stress caused by
pregnancy was high in early
pregnancy and decreased as
pregnancy progressed. Working during
pregnancy did not adversely influence mental and physical stress of pregnant women, while working in early
pregnancy reduced physical stress levels.
Advisors/Committee Members: 樗木, 晶子, 川本, 利恵子.
Subjects/Keywords: Pregnancy; Working; Stress
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
阿南, . (2013). Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. (Thesis). Kyushu University / 九州大学. Retrieved from http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
阿南, あゆみ. “Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.” 2013. Thesis, Kyushu University / 九州大学. Accessed February 26, 2021.
http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
阿南, あゆみ. “Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働.” 2013. Web. 26 Feb 2021.
Vancouver:
阿南 . Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. [Internet] [Thesis]. Kyushu University / 九州大学; 2013. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
阿南 . Mental and Physical Stress of Pregnant Women and Work : 妊婦の精神的・身体的ストレスと労働. [Thesis]. Kyushu University / 九州大学; 2013. Available from: http://hdl.handle.net/2324/21736 ; http://dx.doi.org/10.15017/21736
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Manchester
27.
Hannam, Kimberly.
The effects of air pollution on perinatal outcomes in
North West England.
Degree: 2013, University of Manchester
URL: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713
► Over the past decade there has been a substantial increase in evidence suggesting an increased risk of adverse pregnancy outcomes from ambient air pollution exposure.…
(more)
▼ Over the past decade there has been a substantial
increase in evidence suggesting an increased risk of adverse
pregnancy outcomes from ambient air pollution exposure. However,
there is yet to be enough convincing evidence to confirm a causal
link between specific air pollutants and adverse
pregnancy
outcomes. The objective of this project was to address the paucity
of evidence from the UK on the risk from air pollution in
pregnancy. The research aim was to investigate the effects of
ambient air pollution on adverse
pregnancy outcomes using
retrospective birth outcome data from the ‘North West Perinatal
Survey Unit’ (NWPSU) during the period 2004 to 2008.In addition,
primarily to determine the most appropriate exposure estimation
method, a prospective comparison study (n=85) was performed to
compare personal measurements of nitrogen oxides (NOx) and
specifically nitrogen dioxide (NO₂) with commonly used exposure
estimation techniques. This study informed two further studies
which quantified the effects from air pollution in
pregnancy using
a large retrospective cohort from the NWPSU. The first,
investigated the effects of maternal residential proximity to major
roads on low birthweight (LBW), small for gestational age (SGA) and
preterm birth (PTB). The second, investigated the effects of NOx,
NO₂, carbon monoxide (CO) and particulate matter (PM₂.₅ and PM₁₀)
based on estimates from a novel spatio-temporal air pollution model
and stationary monitor sites on SGA, PTB and mean birth weight
change. Linear and logistic regression models were used to quantify
the risk of adverse
pregnancy outcomes from living in close
proximity to a major road and to specific ambient pollutants. Odds
ratio (OR) associations and mean birth weight change were
calculated for each of the pollutants with exposure averaged over
the entire
pregnancy and for specific
pregnancy periods to
establish critical windows of exposure. Models were adjusted for
maternal age, ethnicity, parity, socio-economic status, birth
season, body mass index and smoking.No statistically significant
associations were found between living <200m from a major road
and adverse
pregnancy outcomes. Based on the spatio-temporal
modelled air pollution estimates, an increased risk of SGA was
found in later
pregnancy with NO₂ (OR=1.14, 95%CI= 1.00-1.30), CO
(OR=1.21, 1.02-1.42), PM₂.₅ (OR=1.10, 1.00-1.21) and PM₁₀ (OR=1.12,
1.00-1.25). This study provides additional evidence that women
exposed to high air pollution concentrations in
pregnancy are at an
increased risk of an SGA birth, but not for PTB. However, there was
no evidence of an effect on SGA for exposures below the current
legal air quality limits.
Advisors/Committee Members: SIBLEY, COLIN CP, AGIUS, RAYMOND R, Mcnamee, Roseanne, Sibley, Colin, Agius, Raymond.
Subjects/Keywords: Air pollution; Pregnancy
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Hannam, K. (2013). The effects of air pollution on perinatal outcomes in
North West England. (Doctoral Dissertation). University of Manchester. Retrieved from http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713
Chicago Manual of Style (16th Edition):
Hannam, Kimberly. “The effects of air pollution on perinatal outcomes in
North West England.” 2013. Doctoral Dissertation, University of Manchester. Accessed February 26, 2021.
http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713.
MLA Handbook (7th Edition):
Hannam, Kimberly. “The effects of air pollution on perinatal outcomes in
North West England.” 2013. Web. 26 Feb 2021.
Vancouver:
Hannam K. The effects of air pollution on perinatal outcomes in
North West England. [Internet] [Doctoral dissertation]. University of Manchester; 2013. [cited 2021 Feb 26].
Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713.
Council of Science Editors:
Hannam K. The effects of air pollution on perinatal outcomes in
North West England. [Doctoral Dissertation]. University of Manchester; 2013. Available from: http://www.manchester.ac.uk/escholar/uk-ac-man-scw:209713

Cornell University
28.
Sones, Jenny.
Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.
Degree: PhD, Physiology, 2015, Cornell University
URL: http://hdl.handle.net/1813/39356
► Preeclampsia (PE) is a devastating disorder of pregnancy that affects 10% of pregnancies worldwide. While it is a leading cause of perinatal morbidity and mortality,…
(more)
▼ Preeclampsia (PE) is a devastating disorder of
pregnancy that affects 10% of pregnancies worldwide. While it is a leading cause of perinatal morbidity and mortality, the cause of PE is unknown. To date the only definitive treatment is delivery of the placenta and the baby, which is often preterm and/or growth restricted. The origins of PE are generally regarded to be early in
pregnancy at the time of placenta formation as placental developmental abnormalities often characterize PE pregnancies. In these thesis studies, early
pregnancy events required for proper placentation, implantation and decidualization, were investigated in the BPH/5 spontaneous mouse model of PE. We discovered profound developmental defects in implantation, decidualization, and placentation in BPH/5 mice. Along with evidence of decidual hypoxia, these defects were associated with a distinct molecular signature of aberrant embryo-uterine interactions. We identified significant dysregulation in the periimplantation period, particularly in the overexpression of cyclooxygenase 2 (Cox2) in the maternal uterine environment. Using pharmacological intervention at early
pregnancy with a selective Cox2 inhibitor, we confirmed that defects in Cox2 signaling during the periimplantation period have "ripple effects" impacting downstream adverse
pregnancy outcomes at mid and late gestation in BPH/5 mice, including fetal growth restriction and demise. Finally, investigations in the periimplantation period lead us to discover deficiencies in immunoregulatory pathways crucial for placental development at the maternal-fetal interface in BPH/5 mice. We showed dramatic loss of decidual Natural Killer (dNK) cells and this was associated with overexpression of IL-15 in BPH/5 implantation sites. Furthermore, we linked Cox2 inhibition with a reduction in IL-15. Altogether, this points towards inflammation in the maternal uterine environment during early
pregnancy having a central role in the poor fetoplacental and
pregnancy outcomes associated with this model and highlights Cox2 inhibitors as potential therapeutics to prevent fetal morbidity/mortality associated with PE. Importantly, our data supports the "ripple effect" hypothesis that defects in early
pregnancy events are the source of downstream adverse
pregnancy outcomes using the BPH/5 mouse model of PE.
Advisors/Committee Members: Davisson, Robin L (chair), Cohen, Paula (committee member), Roberson, Mark Stephen (committee member), Quirk, Susan Mary (committee member).
Subjects/Keywords: preeclampsia; pregnancy; placenta
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sones, J. (2015). Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/39356
Chicago Manual of Style (16th Edition):
Sones, Jenny. “Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.” 2015. Doctoral Dissertation, Cornell University. Accessed February 26, 2021.
http://hdl.handle.net/1813/39356.
MLA Handbook (7th Edition):
Sones, Jenny. “Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia.” 2015. Web. 26 Feb 2021.
Vancouver:
Sones J. Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/1813/39356.
Council of Science Editors:
Sones J. Defects In Periimplantation Signaling Contribute To Adverse Pregnancy Outcomes In The Bph/5 Mouse Model Of Preeclampsia. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/39356

Cornell University
29.
Wilkinson, Amanda.
Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.
Degree: PhD, Nutrition, 2015, Cornell University
URL: http://hdl.handle.net/1813/40599
► Maternal HIV infection during pregnancy is associated with increased risk of adverse obstetric and infant outcomes, and understanding the factors responsible for this association is…
(more)
▼ Maternal HIV infection during
pregnancy is associated with increased risk of adverse obstetric and infant outcomes, and understanding the factors responsible for this association is essential for designing effective interventions. Maternal malnutrition is an important determinant of maternal and infant health for both HIV-infected and - uninfected women. However, the relative contributions of food insecurity and infectioninduced changes in appetite and body weight regulation that alone, or in combination, contribute to malnutrition among HIV-infected women is largely unknown. The goal of this research was to advance the understanding of the underlying mechanisms by which maternal HIV infection influences
pregnancy and early childhood outcomes. A prospective cohort of 114 pregnant women of mixed HIV-status was established in northwestern Tanzania. Pregnant women were followed through delivery and mother-infant dyads participated in follow-up visits at 1, 2, 3 and 6 months postpartum. This study had three main research aims: (1) to investigate maternal HIV and maternal anthropometric indicators as potential determinants of infant outcomes, (2) to characterize maternal and umbilical cord blood cytokine profiles and relate these to infant outcomes, and (3) to evaluate maternal cachexia characteristics during
pregnancy. Maternal HIV status and maternal gestational mid-upper arm circumference (MUAC) were compared to infant anthropometric measurements from birth to six months of age. Infants born to HIV-infected mothers weighed, on average, 235 g less and were 1 cm shorter at birth compared to those born to HIV-uninfected mothers. Among mothers of mixed HIV-status, infants born to women with low MUAC had lower birth length and head circumference than infants born to women with higher MUAC. Maternal HIVinfection and low MUAC were also associated with poorer infant growth indicators through six months postpartum. Examination of cytokine profiles during
pregnancy in this cohort revealed that HIV-infected pregnant women experienced elevated tumor necrosis factor (TNF)-[alpha]inflammation compared to HIV-uninfected pregnant women. On average, TNF-[alpha] concentrations were 14% higher among HIV-infected pregnant women. Among HIVinfected women, longer duration of antiretroviral therapy and more aggressive antiretroviral therapy were associated with more favorable cytokine profiles. Umbilical cord blood cytokine concentrations were used as a proxy for intrauterine exposure. Elevated umbilical cord blood cytokine concentrations were associated with lower infant birth weight and length. Pregnant women were also evaluated based on biopsychosocial characteristics related to cachexia. Based on a modified cachexia scoring system, HIV-infected and HIV-uninfected pregnant women had comparable cachexia symptoms. Evidence of increased gestational cachexia was associated with less favorable infant birth anthropometrics; and, among HIV-infected mothers, cachexia score was associated with lower infant weight-for-age and length-for-age…
Advisors/Committee Members: McDermid,Joann M. (chair), Lujan,Marla E. (committee member), Booth,James (committee member), Brannon,Patsy Marie (committee member).
Subjects/Keywords: HIV; Pregnancy; Cytokines
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Wilkinson, A. (2015). Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/40599
Chicago Manual of Style (16th Edition):
Wilkinson, Amanda. “Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.” 2015. Doctoral Dissertation, Cornell University. Accessed February 26, 2021.
http://hdl.handle.net/1813/40599.
MLA Handbook (7th Edition):
Wilkinson, Amanda. “Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants.” 2015. Web. 26 Feb 2021.
Vancouver:
Wilkinson A. Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. [Internet] [Doctoral dissertation]. Cornell University; 2015. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/1813/40599.
Council of Science Editors:
Wilkinson A. Maternal Determinants Of Fetal Growth, Pregnancy Outcomes, And Early Childhood Growth And Development Among Hiv-Exposed And Hiv-Unexposed Infants. [Doctoral Dissertation]. Cornell University; 2015. Available from: http://hdl.handle.net/1813/40599

Cornell University
30.
Young, Melissa.
Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.
Degree: PhD, Nutrition, 2011, Cornell University
URL: http://hdl.handle.net/1813/33570
► Iron deficiency anemia is the most common nutrient deficiency in the world , with highest rates in pregnant women and young children. Despite the magnitude…
(more)
▼ Iron deficiency anemia is the most common nutrient deficiency in the world , with highest rates in pregnant women and young children. Despite the magnitude and severity of iron deficiency, there remains gaps in our knowledge of iron metabolism. Hepcidin is a key regulator of iron homeostasis yet limited data is available on its role during
pregnancy. Although our knowledge of non-heme iron metabolism has increased substantially in recent years, the mechanisms regulating heme iron metabolism remain elusive. The overall goal o f this research is to further understand the primary determinants of iron absorption and placental iron transfer in women of childbearing age. To address these issues stable iron isotopes (57Fe and 58Fe) were used to measure iron absorption in non-pregnant (ages 18-32 years, n = 30) and pregnant (ages 16-32 years, n = 20) subjects and placental iron transfer in pregnant women. Nonheme iron absorption was inversely associated with iron status and serum hepcidin. However, heme iron absorption was not signif icantly associated with serum hepcidin or iron stores, suggesting differential regulation. In a subset of 18 non-pregnant subjects serum prohepcidin (hepcidin precursor) was also assessed but was not significantly associated with measures of iron absorptio n or serum hepcidin. Both pregnant and non-pregnant women absorbed significantly more iron from a heme based meal compared to a non-heme iron supplement. Interestingly there also appears to be preferential fetal utilization of maternally ingested heme iron compared to nonheme iron during
pregnancy. Iron status in the maternal-neonatal dyad and maternal serum hepcidin were inversely associated with heme and non-heme placental iron transfer. In a cohort of 92 pregnant adolescents (ages 14-18 years), the placental protein expression of transferrin receptor was likewise increased in response to altered iron stores in the mother and neonate. Despite increased iron absorption by women during
pregnancy, placental iron transporter expression and placental iron tr ansfer, many of the mothers and the neonates had suboptimal iron status at the time of delivery. Based on study results, further research on the mechanisms of heme iron metabolism and mechanisms of placental iron transfer are warranted.
Advisors/Committee Members: O'Brien, Kimberly O (chair), Haas, Jere Douglas (committee member), Pinstrup-Anderson, Per (committee member), Olson, Christine Marie (committee member).
Subjects/Keywords: Iron; Pregnancy; Hepcidin
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APA (6th Edition):
Young, M. (2011). Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. (Doctoral Dissertation). Cornell University. Retrieved from http://hdl.handle.net/1813/33570
Chicago Manual of Style (16th Edition):
Young, Melissa. “Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.” 2011. Doctoral Dissertation, Cornell University. Accessed February 26, 2021.
http://hdl.handle.net/1813/33570.
MLA Handbook (7th Edition):
Young, Melissa. “Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer.” 2011. Web. 26 Feb 2021.
Vancouver:
Young M. Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. [Internet] [Doctoral dissertation]. Cornell University; 2011. [cited 2021 Feb 26].
Available from: http://hdl.handle.net/1813/33570.
Council of Science Editors:
Young M. Iron Absortpion In Pregnant And Non-Pregnant Women And Mechanisms Of Placental Iron Transfer. [Doctoral Dissertation]. Cornell University; 2011. Available from: http://hdl.handle.net/1813/33570
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