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You searched for subject:( Glomeruloesclerose). Showing records 1 – 2 of 2 total matches.

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Universidade do Rio Grande do Norte

1. Lima, Kaio Ramon de Aguiar. Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 .

Degree: 2018, Universidade do Rio Grande do Norte

Cancer-related cachexia leads to metabolic changes leading to increased oxidative stress and inflammation that may promote morphological and physiological changes in different organs. This work aimed to describe morphologically the glomerular changes due to cachexia and the effect of supplementation with L-glutamine (2%) on renal protection. Twenty male Wistar rats were used, distributed in four groups: control (C); tumor carriers of Walker-256 (TW); control supplemented with 2% L-glutamine (CG) and Walker-256 tumor carriers supplemented with 2% L-glutamine (TWG). The results demonstrated a reduction of the glomerular density in the TW group and a decrease in the glomerular loss in TWG. There was an increase in the area of the glomerular tuft and reduction of the urinary space in TW. The area of the glomerular mesangium was larger in the TW and TWG than in the C groups, but TWG was smaller than TW. The percentage of the area occupied by extracellular matrix in the glomerular tuft was higher in TW and TWG. The glomerular area occupied by collagen was higher in TW and TWG, but it was lower in the treated group. FGF-2 expression was higher in the TW group, whereas TWG showed the lowest immunolabelling of all groups. The data indicate that the cachexia in the kidney changes the glomerular morphology with loss of glomeruli and glomerular fibrosis. Such changes can lead to functional renal impairment compromising renal filtration and levels of eliminated substances, which serve as indicators for drug dose adequacy and for treatment. On the other hand, supplementation with L-glutamine improves most of the analyzed parameters, minimizing the effects of cachexia in the treated animals, especially glomerular density and renal fibrosis, justifying its use in the treatment of cancer patients. Advisors/Committee Members: Clebis, Naianne Kelly (advisor), 02441924990 (advisor).

Subjects/Keywords: Câncer; Rim; Antioxidantes; Glomeruloesclerose

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Lima, K. R. d. A. (2018). Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 . (Masters Thesis). Universidade do Rio Grande do Norte. Retrieved from http://repositorio.ufrn.br/handle/123456789/25209

Chicago Manual of Style (16th Edition):

Lima, Kaio Ramon de Aguiar. “Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 .” 2018. Masters Thesis, Universidade do Rio Grande do Norte. Accessed October 16, 2019. http://repositorio.ufrn.br/handle/123456789/25209.

MLA Handbook (7th Edition):

Lima, Kaio Ramon de Aguiar. “Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 .” 2018. Web. 16 Oct 2019.

Vancouver:

Lima KRdA. Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 . [Internet] [Masters thesis]. Universidade do Rio Grande do Norte; 2018. [cited 2019 Oct 16]. Available from: http://repositorio.ufrn.br/handle/123456789/25209.

Council of Science Editors:

Lima KRdA. Efeito da L-glutamina na morfologia glomerular de ratos portadores de tumor de Walker-256 . [Masters Thesis]. Universidade do Rio Grande do Norte; 2018. Available from: http://repositorio.ufrn.br/handle/123456789/25209

2. Priscylla Aparecida Vieira do Carmo. ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA.

Degree: 2008, Universidade Federal de Juiz de Fora

As glomerulopatias persistem entre as principais causas de doença renal crônica dialítica em nosso país. Traçar um perfil destas doenças assume importância não só como fonte para investigações clínicas e epidemiológicas, como também constitui-se em importante passo para o conhecimento da história natural das doenças glomerulares. O presente estudo avaliou o perfil das doenças glomerulares na Zona da Mata Mineira, estabelecendo a distribuição e freqüência dos tipos histológicos das glomerulopatias primárias e secundárias, relacionando-os com os achados clínicolaboratoriais. Foram realizadas 261 biópsias, sendo que 126 delas correspondiam a rins nativos de adultos e foram consideradas para análise. A síndrome glomerular mais freqüente foi a nefrótica (55,2%), seguida da síndrome de anormalidades urinárias (28,8%). As glomerulopatias primárias e secundárias predominantes foram a glomeruloesclerose segmentar e focal (40,8%) e a nefrite lúpica (80,7%), respectivamente. Considerando-se toda a população, a GESF foi a glomerulopatia predominante (n=31; 24,6%), seguida pela nefrite lúpica (n=21; 16,6%) e pela nefropatia por IgA (n=16; 12,6%). Dentre as principais causas de síndrome nefrótica, a 10 GESF foi a glomerulopatia mais freqüentemente encontrada (27,5%), seguida pela nefrite lúpica (23,1%). Na síndrome de anormalidades urinárias, os diagnósticos mais freqüentes foram o rim normal (27,7%) e a nefropatia por IgA (22,2%). A maioria dos pacientes avaliados apresentavam algum grau de cronicidade à biópsia renal (56,3%), que se relacionou com menores valores de filtração glomerular. Este estudo forneceu informações importantes sobre as glomerulopatias na nossa região, contribuindo não só para uma adequada documentação da distribuição destas doenças entre nós, mas sobretudo para definição de melhores condutas visando terapêuticas cada vez mais específicas para diferentes tipos histológicos

Glomerulopathies are still among the main causes of chronic kidney diseases requiring dialysis in our country. It is important to establish a profile of these diseases not only as a source for clinical and epidemiological investigations, but also because this is an important step for the knowledge of the natural history of glomerular diseases. This study assessed the profile of glomerular diseases in the Zona da Mata region of Minas Gerais, and established the distribution and frequency of the histological types of primary and secondary glomerulopathies, comparing them to clinical-laboratorial results. 261 biopsies were carried out, 126 of which were native adult kidneys and which were submitted to analysis. The most common glomerular syndrome was nephrotic syndrome (55.2%), followed by urinary abnormality syndrome (28.8%). The predominant primary and secondary glomerulopathies were focal segmental glomerulosclerosis (40.8%) and lupus nephritis (80.7%), respectively. Considering the whole population, FSGS was the predominant glomerulopathy (n=31; 24.6%), followed by lupus nephritis (n=21; 16.6%) and IgA nephropathy (n=16; 12.6%). Among…

Advisors/Committee Members: Marcello Fabiano de Franco, Patricia Ferreira Abreu, Hélady Sanders Pinheiro, Sonia Maria Neumann Cupolilo, Luiz Carlos Ferreira de Andrade.

Subjects/Keywords: SAUDE COLETIVA; glomerulopatias; biópsia renal; glomeruloesclerose segmentar e focal; nefrite lúpica; síndrome nefrótica; anormalidades urinárias; Glomerulopathies; Renal Biopsy; Focal Segmental Glomerulosclerosis Lupus Nephritis; Nephrotic Syndrome; Urinary Abnormalities

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Carmo, P. A. V. d. (2008). ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA. (Thesis). Universidade Federal de Juiz de Fora. Retrieved from http://www.bdtd.ufjf.br/tde_busca/arquivo.php?codArquivo=183

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Carmo, Priscylla Aparecida Vieira do. “ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA.” 2008. Thesis, Universidade Federal de Juiz de Fora. Accessed October 16, 2019. http://www.bdtd.ufjf.br/tde_busca/arquivo.php?codArquivo=183.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Carmo, Priscylla Aparecida Vieira do. “ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA.” 2008. Web. 16 Oct 2019.

Vancouver:

Carmo PAVd. ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA. [Internet] [Thesis]. Universidade Federal de Juiz de Fora; 2008. [cited 2019 Oct 16]. Available from: http://www.bdtd.ufjf.br/tde_busca/arquivo.php?codArquivo=183.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Carmo PAVd. ESTUDO DAS DOENÇAS GLOMERULARES NA ZONA DA MATA MINEIRA. [Thesis]. Universidade Federal de Juiz de Fora; 2008. Available from: http://www.bdtd.ufjf.br/tde_busca/arquivo.php?codArquivo=183

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.