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1.
[No author].
Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
.
Degree: 2009, Fundação Escola de Comércio Ãlvares Penteado
URL: http://132.0.0.61:8080/tede/handle/tede/546
► Aiming to understand the relationship between the collection of the major state taxes - ICMS (VAT) and IPVA - and GDP in all units of…
(more)
▼ Aiming to understand the relationship between the collection of the major state taxes - ICMS (VAT) and IPVA - and GDP in all units of the Federation in the period 1997 to 2006, it is an expression statistic for estimating this relationship and a ranking showing the degree of affinity between the collection of taxes mentioned state and GDP statistics for the equation, using the simple linear regression with its main premises in order to understand this relationship, whereas the GDP reflects the size of the economy of each state. The data concerning the current GDP was taken from the IBGE site which was used for comparison with the collection of IPVA. The current GDP, also served as a basis for calculating the adjusted GDP, of which exports were removed (free of VAT) and imports added (taxed by ICMS) to compare with the ICMS through simple linear regressions, while the values of the collections the ICMS and IPVA were taken from the site CONFAZ, organ of the Ministry of Finance to disclose such data. In the results, the equations are seen statistics that could estimate the tax, in addition to providing the development of the ranking. The survey results showed that 77.78% of the units in the Federation there is a greater increase in the collection of VAT and IPVA on the increase in GDP, ie, in most states to collect such taxes had a greater proportional increase that
the increase of wealth in their economies.
Advisors/Committee Members: Gallo, Mauro Fernando (advisor), CPF:18398782820 (advisor), http://lattes.cnpq.br/5908013690653416 (advisor).
Subjects/Keywords: Impostos - Brasil;
Imposto sobre circula????o de mercadorias e servicos;
Imposto sobre a propriedade de ve??culos automotores;
Produto interno bruto;
Gross state product;
Brazil;
Motor vehicles taxation;
Value-added tax
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2009). Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
. (Thesis). Fundação Escola de Comércio Ãlvares Penteado. Retrieved from http://132.0.0.61:8080/tede/handle/tede/546
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
.” 2009. Thesis, Fundação Escola de Comércio Ãlvares Penteado. Accessed January 26, 2021.
http://132.0.0.61:8080/tede/handle/tede/546.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
.” 2009. Web. 26 Jan 2021.
Vancouver:
author] [. Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
. [Internet] [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2009. [cited 2021 Jan 26].
Available from: http://132.0.0.61:8080/tede/handle/tede/546.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Avalia????o da arrecada????o dos principais impostos estaduais - ICMS e IPVA - em rela????o ao Produto Interno Bruto
. [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2009. Available from: http://132.0.0.61:8080/tede/handle/tede/546
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
2.
[No author].
Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
.
Degree: 2016, Fundação Escola de Comércio Ãlvares Penteado
URL: http://tede.fecap.br:8080/jspui/handle/jspui/703
► The Government Accounting Brazilian converges IPSAS, were created several standards, impacting Demonstrative and Subsystems. Meantime, there are conflicting aspects and HEI are to prepare the…
(more)
▼ The Government Accounting Brazilian converges IPSAS, were created several standards, impacting Demonstrative and Subsystems. Meantime, there are conflicting aspects and HEI are to prepare the graduate with skills required. Having that said, this research objective to identify the perception of teachers of the Government Accounting about the teaching conditions and the need in Courses of Accounting in the Baixada Santista region. Was conducted exploratory and qualitative research; data collection techniques were interview and document analysis. Were taken sample, 7 teachers who teach the discipline in 7 courses in accounting sciences in HEI in the region in 2015. It requested the teaching plans to 7 teachers. The results showed that 42.85% are accountants, 42.85% has Masters, 71.42% have up to 6 years of experience. In teaching strategies and evaluation, expositive classes and exercises were the most mentioned. All use tests, practical exercises and assignments. Regarding workload, 71.42% have reported failure. As for literature, lack autonomy of teachers, most use outdated plans. As for NBCT16, 57.14% say they consider the program. About the last question, it was sought to go deeper concerning what??s taught, 100% do not address differences between MCASP and IPSAS, 42,85% use the current subsystems and property aspects. It got to the conclusion and, it??s recommended, changing plans after 6 months, sources?? inclusion teacher autonomy in preparing the plan, expansion of the workload and expansion of content regarding on MCASP / IFAC / NBCT16. Though there??s an affirmation from all teachers that applied content so far meets the demands of the contests for Accountant, the results demonstrate that there are need to expand the expertise to students.
Advisors/Committee Members: PELEIAS, Ivam Ricardo (advisor), http://lattes.cnpq.br/1583907056732686 (advisor).
Subjects/Keywords: Contabilidade ??? Estudo e ensino - Baixada Santista (SP). Curr??culos ??? Educa????o - Baixada Santista (SP). Contabilidade p??blica - Estudo e ensino (Superior).;
Accounting - Study and teaching - Baixada Santista (SP). Education - Curricula - Baixada Santista (SP). Finance public - Study and teaching (Higher).
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2016). Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
. (Thesis). Fundação Escola de Comércio Ãlvares Penteado. Retrieved from http://tede.fecap.br:8080/jspui/handle/jspui/703
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
.” 2016. Thesis, Fundação Escola de Comércio Ãlvares Penteado. Accessed January 26, 2021.
http://tede.fecap.br:8080/jspui/handle/jspui/703.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
.” 2016. Web. 26 Jan 2021.
Vancouver:
author] [. Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
. [Internet] [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2016. [cited 2021 Jan 26].
Available from: http://tede.fecap.br:8080/jspui/handle/jspui/703.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Percep????es de professores de contabilidade governamental sobre as condi????es de ensino e necessidade da disciplina em cursos de ci??ncias cont??beis da regi??o metropolitana da baixada santista
. [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2016. Available from: http://tede.fecap.br:8080/jspui/handle/jspui/703
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
3.
[No author].
Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
.
Degree: 2018, Fundação Escola de Comércio Ãlvares Penteado
URL: http://tede.fecap.br:8080/jspui/handle/jspui/792
► his research had as objective to analyze the perceptions about functions and competences of the coordinator as manager of the undergraduate course in Accounting Sciences…
(more)
▼ his research had as objective to analyze the perceptions about functions and competences of the coordinator as manager of the undergraduate course in Accounting Sciences offered by private higher education institutions in Brazil. For this, a descriptive research with a quantitative approach was carried out. The data were collected through an online questionnaire with structured and "free" questions. Data analysis was performed using statistical methods and content analysis. It was verified that in the dimension of the
competences the pedagogic one stands out being more expressive the "Knowledge of the
curricular management and the articulation between its components and processes" with
(4.37) and the administrative one, being less expressive the "Elaboration and control of the budget course" with (3.21). In the dimension of the functions, the most important is the institutional one, with the most expressive being the "Search for the success of the students in the National Exam of the course and in the tests of order" with (4.63), and the managerial one being less expressive the "Contractual students and the use of negotiation criteria" with (2.42). As for the factors that hinder the management of the course, the coordinators cite as the most expressive the centralized university management (20%); lack of time to manage the course (16%); the lack of training in academic management (10%). Already as factors that facilitates citation training for academic management (24%); the exercise of leadership (20%) and the. This seems to be the profile of a manager put into practice in order to meet the educational demands, which require, in addition to technical knowledge for the performance of bureaucratic functions, also cognitive and socioaffective capacities in the execution of complex tasks such as those of a political-pedagogical, administrative, institutional and relational. It can be concluded that the professional who acts as manager of the course in Accounting Sciences guides his actions in the search for the preparation of the egress to obtain professional success and, thus, the achievement of institutional success, based less on the knowledge of academic management and relational (attitudes) and more in the knowledge of the exercise of the profession (know - how).
Advisors/Committee Members: SLOMSKI, Vilma Geni (advisor), http://lattes.cnpq.br/4037547425398159 (advisor).
Subjects/Keywords: 1. Contabilidade - Estudo e Ensino - Brasil. 2. Educa????o Baseada na compet??ncia. 3. Compet??ncias essenciais - Estudo e ensino. 4. Curr??culos - Mudan??as - Contabilidade.;
1. Accounting - Study and teaching - Brazil. 2. Competency based educatio. 3. Core competencies - Study and teaching. 4. Courses of study - Accounting .
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2018). Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
. (Thesis). Fundação Escola de Comércio Ãlvares Penteado. Retrieved from http://tede.fecap.br:8080/jspui/handle/jspui/792
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
.” 2018. Thesis, Fundação Escola de Comércio Ãlvares Penteado. Accessed January 26, 2021.
http://tede.fecap.br:8080/jspui/handle/jspui/792.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
.” 2018. Web. 26 Jan 2021.
Vancouver:
author] [. Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
. [Internet] [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2018. [cited 2021 Jan 26].
Available from: http://tede.fecap.br:8080/jspui/handle/jspui/792.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Percep????es sobre fun????es e compet??ncias do coordenador como gestor do curso de gradua????o em ci??ncias cont??beis oferecido por institui????es privadas de ensino superior brasileiras
. [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2018. Available from: http://tede.fecap.br:8080/jspui/handle/jspui/792
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
4.
[No author].
An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
.
Degree: 2001, Fundação Escola de Comércio Ãlvares Penteado
URL: http://132.0.0.61:8080/tede/handle/tede/296
► The purpose of this work is to determine what is being taught in the discipline of Statistic in the Business Administration courses of the city…
(more)
▼ The purpose of this work is to determine what is being taught in the discipline of Statistic in the Business Administration courses of the city of S??
o Paulo. This study begins with an explanation of the development of the college education and of Business Administration courses in Brazil. It analyzes the planing of the Business Administration course in an attempt to verify whether the teaching of Statistics complies with the current legislation. It examines the proposals of the Curricula Guidelines, which have been submitted to the Ministry of Education - MEC for approval. The methodology used in this study included surveying the course planning programs adopted by the institutions in the city of Sao Paulo, which have their Business Administration course approved by the MEC. This data gathering resulted in 18 planing programs collected among 35 institutions. The analyses of these plans included all topics they should cover. However the findings showed that the institutions do not take plans totally into consideration and, although they are compatible with their stated purposes, their contents are not consistent with the actual demands of the professional market. Basically, all institutions employ the same methods and teaching techniques mentioned in the planning programs, that is, lecture sessions followed by practical exercises. The assessment criteria is practically the same among all institutions with testes and lists of exercises. More importantly, there is an excessive number of reference books of which many titles are sold out or outdated. We believe that this study may be useful not only for university teachers but also for School Managers. The conclusions may lead teachers to reflect on needed improvements in the teaching of Statistics, and School Managers, to reflect on the course curricula.
Advisors/Committee Members: Godoy, Arilda Schimidt (advisor), CPF:88888888888 (advisor).
Subjects/Keywords: Administra????o de empresas - Estudo e ensino (Superior);
Estat??stica - Curr??culos - Planejamento;
Statistics - Curriculum planning;
Business management - Study and teaching (Higher)
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2001). An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
. (Thesis). Fundação Escola de Comércio Ãlvares Penteado. Retrieved from http://132.0.0.61:8080/tede/handle/tede/296
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
.” 2001. Thesis, Fundação Escola de Comércio Ãlvares Penteado. Accessed January 26, 2021.
http://132.0.0.61:8080/tede/handle/tede/296.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
.” 2001. Web. 26 Jan 2021.
Vancouver:
author] [. An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
. [Internet] [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2001. [cited 2021 Jan 26].
Available from: http://132.0.0.61:8080/tede/handle/tede/296.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. An??lise da disciplina "Estat??stica" no curso de administra????o de empresas
. [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2001. Available from: http://132.0.0.61:8080/tede/handle/tede/296
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
5.
[No author].
Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
Degree: 2016, Fundação Escola de Comércio Ãlvares Penteado
URL: http://tede.fecap.br:8080/jspui/handle/jspui/721
► The aim of this research was to analyze the consistency between the Teaching Project, the legislation relevant to the university education in Brazil, and the…
(more)
▼ The aim of this research was to analyze the consistency between the Teaching Project, the legislation relevant to the university education in Brazil, and the teaching practices, in the view of the coordinator and professors from an Accounting Sciences graduation course in the city of S??
o Paulo. It was a qualitative research. Firstly, it was applied an interview scrip. Secondly, with the professors. The results from the first stage show that, according to the coordinator, the competency approach is dealt with since the beginning of the course, and in all disciplines: basic, professional, theoretical and practical. The results from the second stage show that, despite working the competency approach, most professors do not know the concept of competency-based education, but apply this concept, although not knowing the theory. This stage also verified that the Teaching Project is in accordance with the National Curricular Guidelines.
Advisors/Committee Members: PELEIAS, Ivam Ricardo (advisor), http://lattes.cnpq.br/1583907056732686 (advisor).
Subjects/Keywords: Ensino superior - Pesquisa. Curr??culos. Compet??ncias;
Education, Higher - Research. Education - Curricula. Core competencies.
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
author], [. (2016). Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
(Thesis). Fundação Escola de Comércio Ãlvares Penteado. Retrieved from http://tede.fecap.br:8080/jspui/handle/jspui/721
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
author], [No. “Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
” 2016. Thesis, Fundação Escola de Comércio Ãlvares Penteado. Accessed January 26, 2021.
http://tede.fecap.br:8080/jspui/handle/jspui/721.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
author], [No. “Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
” 2016. Web. 26 Jan 2021.
Vancouver:
author] [. Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
[Internet] [Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2016. [cited 2021 Jan 26].
Available from: http://tede.fecap.br:8080/jspui/handle/jspui/721.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
author] [. Estudo da percep????o sobre a no????o de compet??ncias no projeto pol??tico pedag??gico em um curso superior de Ci??ncias Cont??beis sob o olhar do Coordenador e dos Professores.
[Thesis]. Fundação Escola de Comércio Ãlvares Penteado; 2016. Available from: http://tede.fecap.br:8080/jspui/handle/jspui/721
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
6.
Malet, Julien.
Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes.
Degree: Docteur es, Biologie. Microbiologie Procaryote et Eucaryote, 2016, Sorbonne Paris Cité
URL: http://www.theses.fr/2016USPCC165
► Listeria monocytogenes est une bactérie pathogène responsable de la listériose chez l’homme. Cette bactérie est capable d’envahir et de se répliquer dans des cellules phagocytaires…
(more)
▼ Listeria monocytogenes est une bactérie pathogène responsable de la listériose chez l’homme. Cette bactérie est capable d’envahir et de se répliquer dans des cellules phagocytaires et non-phagocytaires de l’hôte. De fait, Listeria interagit et interfère avec de nombreux composants cellulaires au cours de sa réplication. Mon projet de thèse s’est focalisé sur les altérations du protéome des cellules infectées par Listeria. Je me suis en particulier intéressé à l’activation de protéases de l’hôte et aux dégradations de certains facteurs cellulaires en réponse à l’infection.Une analyse protéomique de cellules humaines traitées avec la Listeriolysine O (LLO), une toxine secrétée par Listeria formant des pores dans les membranes cellulaires, nous a permis d’identifier plusieurs dizaines de facteurs cellulaires dégradés en réponse à l’exposition à cette toxine.Nous avons pu confirmer la dégradation de ces protéines dans le contexte d’une infection par Listeria in vitro (dans un modèle de cellules en culture) et in vivo (dans un modèle animal). Nous anticipons que la dégradation de ces protéines, impliquées dans différentes fonctions cellulaires, joue un rôle au cours de l’infection par Listeria en modifiant la physiologie des cellules hôte.Nous avons en parallèle mis en évidence que Listeria interfère avec le fonctionnement des lysosomes. Nous avons montré que la LLO déstabilise les lysosomes des cellules hôtes et induit leur perméabilisation. Ceci permet la libération de certaines protéases lysosomales, telles que les cathepsines, dans le cytosol des cellules hôte. Ces cathepsines, une fois libérées, pourraient alors cliver différentes protéines cytosoliques et ainsi modifier la physiologie des cellules infectées.L’ensemble de mes travaux a permis de montrer que Listeria interfère avec le fonctionnement de nombreuses protéases de l’hôte et induit la dégradation de plusieurs facteurs cellulaires. Ces cibles dégradées constituent une nouvelle classe de protéines dont nous pouvons maintenant tester le rôle potentiel dans l’infection. Mes travaux ont d’autre part permis de montrer que d’autres toxines bactériennes, similaires à la LLO, induisent également des altérations du protéome des cellules hôtes. Ceci suggère que les mécanismes identifiés avec Listeria sont conservés entre différentes classes de pathogènes bactériens.
Listeria monocytogenes is a foodborne pathogen responsible for human listeriosis which invade and replicate in both phagocytic and non-phagocytic cells. Listeria intracellular life cycle involves interference with host cell components. My PhD project aims to characterize host cell proteome modifications in cells infected by Listeria. I focused my research on host proteases activation and the degradation of host cell proteins in response to infection. A proteomic analysis performed on cells treated with purified Listeriolysin O (LLO), a pore forming toxin secreted by Listeria, identified more than 90 proteins degraded in response to the toxin. We validated the degradation of these proteins using both in…
Advisors/Committee Members: Cossart, Pascale (thesis director).
Subjects/Keywords: Listeriolysine O; Listeriolysin O
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Malet, J. (2016). Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes. (Doctoral Dissertation). Sorbonne Paris Cité. Retrieved from http://www.theses.fr/2016USPCC165
Chicago Manual of Style (16th Edition):
Malet, Julien. “Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes.” 2016. Doctoral Dissertation, Sorbonne Paris Cité. Accessed January 26, 2021.
http://www.theses.fr/2016USPCC165.
MLA Handbook (7th Edition):
Malet, Julien. “Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes.” 2016. Web. 26 Jan 2021.
Vancouver:
Malet J. Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes. [Internet] [Doctoral dissertation]. Sorbonne Paris Cité; 2016. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2016USPCC165.
Council of Science Editors:
Malet J. Altération du protéome de la cellule hôte en réponse à l'infection par listeria monocytogenes : Alteration of host cell proteome during infection by Listeria monocytogenes. [Doctoral Dissertation]. Sorbonne Paris Cité; 2016. Available from: http://www.theses.fr/2016USPCC165
7.
Lafont, Florian.
Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response.
Degree: Docteur es, Aspects moléculaires et cellulaires de la biologie, 2017, Nantes
URL: http://www.theses.fr/2017NANT1023
► Les cellules humaines sont soumises à des stress induisant des cassures double-brin de l’ADN principalement réparées par la voie NHEJ, où la kinase DNA-PKcs joue…
(more)
▼ Les cellules humaines sont soumises à des stress induisant des cassures double-brin de l’ADN principalement réparées par la voie NHEJ, où la kinase DNA-PKcs joue un rôle central. L’activité de DNA-PKcs, régulée par de nombreuses phosphorylations, est cruciale pour le maintien de l’intégrité génomique. Plus récemment, il a été montré que cette protéine était également modifiée par l’O-GlcNAcylation dans la lignée COS7. Sachant l’équilibre existant entre phosphorylation et O-GlcNAcylation, nous avons étudié le rôle de cette nouvelle MPT dans la régulation de l’activité de DNA- PKcs. Nous avons montré que DNA-PKcs est O-GlcNAcylée dans les cellules HeLa. Puis nous avons montré que la modulation de l’O-GlcNAcylation de DNA-PKcs impacte son autophosphorylation en Ser2056, suggérant l’existence d’une balance O-GlcNAcylation /phosphorylation, ainsi que la capacité des cellules à réparer les DSBs par la voie NHEJ. De plus, nos résultats nous laissent envisager que cette modification puisse jouer un rôle dans la stabilité de la protéine. DNA-PKcs est une cible potentielle dans les stratégies de lutte contre le cancer. Nous avons étudié l’impact d’un composé sur DNA-PKcs. Cette molécule provoque une réduction de la quantité et de l’activité de DNA-PKcs, impliquant son ubiquitinylation et sa dégradation par le protéasome et menant à une sensibilisation des cellules à un traitement génotoxique. Dans ce contexte, nous avons développé une puce à anticorps pour évaluer le profil phosphoprotéique des voies de réparation de l’ADN et ainsi évaluer l’effet d’inhibiteurs de DNA-PKcs. L’ensemble de ces résultats contribuent à une meilleure compréhension de la régulation de DNA-PKcs.
Human cells are subjected to stresses inducing DNA double-strand breaks mainly repaired by the NHEJ pathway, where the kinase DNA-PKcs plays a central role. The activity of DNA-PKcs, regulated by numerous phosphorylations, is crucial for the maintenance of genomic integrity. More recently, it has been shown that this protein is also modified by O-GlcNAcylation in the COS7 cell line. Knowing the balance between phosphorylation and O-GlcNAcylation, we studied the role of this new PTM in the regulation of DNA-PKcs activity. We have shown that DNA-PKcs is O-GlcNAcylated in HeLa cells. We then showed that the modulation of DNA-PKcs O-GlcNAcylation affects its autophosphorylation on Ser2056, suggesting an O-GlcNAcylation/phosphorylation balance, as well as the ability of cells to repair DSBs by NHEJ pathway. Moreover, our results allow us to consider that this modification may play a role in protein stability. DNA-PKcs is a potential target in anticancer strategies. We studied the impact of a chemical compound on DNA-PKcs activity. This molecule causes a reduction in the amount and activity of DNA-PKcs, through its ubiquitinylation and its degradation by the proteasome and leading to sensitization of the cells to genotoxic treatment. In this context, we have developed an antibody microarray to evaluate the phosphoprotein level of DNA repair pathways and thus…
Advisors/Committee Members: Fleury, Fabrice (thesis director), Benhelli Mokrani, Houda (thesis director).
Subjects/Keywords: O-GlcNAcylation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Lafont, F. (2017). Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response. (Doctoral Dissertation). Nantes. Retrieved from http://www.theses.fr/2017NANT1023
Chicago Manual of Style (16th Edition):
Lafont, Florian. “Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response.” 2017. Doctoral Dissertation, Nantes. Accessed January 26, 2021.
http://www.theses.fr/2017NANT1023.
MLA Handbook (7th Edition):
Lafont, Florian. “Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response.” 2017. Web. 26 Jan 2021.
Vancouver:
Lafont F. Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response. [Internet] [Doctoral dissertation]. Nantes; 2017. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2017NANT1023.
Council of Science Editors:
Lafont F. Implication des modifications post-traductionnelles de DNA-PKcs dans la régulation de la réponse aux dommages à l'ADN. : Involvement of DNA-PKcs post-translational modifications in the regulation of DNA damage response. [Doctoral Dissertation]. Nantes; 2017. Available from: http://www.theses.fr/2017NANT1023
8.
Ortega, Frank J.
Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers.
Degree: 2013, Texas Digital Library
URL: http://hdl.handle.net/1969;
http://hdl.handle.net/2249.1/66683
► Latina/o health discourses stem from historical and social notions of biological, cultural, and racial inferiority. Popular U.S. newspapers pay scant attention to Latina/o health concerns…
(more)
▼ Latina/
o health discourses stem from historical and social notions of biological, cultural, and racial inferiority. Popular U.S. newspapers pay scant attention to Latina/
o health concerns and often inaccurately portray Latinas/os as undeserving foreigners that continue to drain social services such as health care. A content analysis of 291 New York Times, Los Angeles Times, Chicago Tribune, and Houston Chronicle newspaper articles (2006-2010) reveals that Latina/
o health discourses are grounded in a racialized medical narrative that justifies and sustains white racial oppression. Systemic racism and the white racial frame are utilized as theoretical frameworks to better understand how mainstream newspapers construct the medical racialization of Latinas/os and contribute to health disparities, unequal access to health services, and inadequate health care. The findings reveal that Latina/
o health issues concerning high costs, population increase, and political marginality, influence anti-Latina/
o legislation, sustain prevailing racism, and create exclusionary health practices. Fundamentally the anti-Latina/
o sentiment presented in the newspapers and disseminated throughout society equates to the denial of resources, the denial of health care, and thus the denial of life. Challenging racist Latina/
o perceptions is an important area of social science and anti-racism research. Ultimately, without a healthy Latina/
o workforce, the economy could not sustain itself and society would be susceptible to economic, social, and political collapse.
Advisors/Committee Members: Feagin, Joe (advisor).
Subjects/Keywords: Latina/o
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ortega, F. J. (2013). Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers. (Thesis). Texas Digital Library. Retrieved from http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66683
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Ortega, Frank J. “Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers.” 2013. Thesis, Texas Digital Library. Accessed January 26, 2021.
http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66683.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Ortega, Frank J. “Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers.” 2013. Web. 26 Jan 2021.
Vancouver:
Ortega FJ. Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers. [Internet] [Thesis]. Texas Digital Library; 2013. [cited 2021 Jan 26].
Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66683.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Ortega FJ. Latina/o Health Discourses in Newsprint Media from 2006-2010: A Content Analysis of Four Syndicated Newspapers. [Thesis]. Texas Digital Library; 2013. Available from: http://hdl.handle.net/1969; http://hdl.handle.net/2249.1/66683
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
9.
Ferron, Marine.
Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock.
Degree: Docteur es, Biologie, médecine et santé, 2017, Nantes
URL: http://www.theses.fr/2017NANT1046
► L'insuffisance cardiaque (IC) touche 1-2% des adultes dans les pays développés. On distingue classiquement 2 formes d’IC : l’IC chronique, dont la mise en place…
(more)
▼ L'insuffisance cardiaque (IC) touche 1-2% des adultes dans les pays développés. On distingue classiquement 2 formes d’IC : l’IC chronique, dont la mise en place est lente, et l’IC aigue dont l’apparition est rapide ou due à l'aggravation des symptômes et/ou des signes de l’IC. Quelles soient chroniques ou aigues, certaines formes d'IC n'ont pas de traitement efficace. L'insuffisance cardiaque à fraction d'éjection préservée (ICFEp) devient la forme prédominante d'IC chronique mais la compréhension de sa physiopathologie reste encore incomplète. Un modèle de rat transgénique sur-exprimant le récepteur β3- adrénergique humain au niveau endothélial a été développé dans l'équipe. Comme les patients, ce modèle développe une ICFEp avec l’âge qui se manifeste notamment par une dysfonction diastolique et une intolérance au stress. Dans le cadre de ma thèse et sur la base d'une étude transcriptomique, j'ai évalué les altérations du cycle du calcium, du métabolisme ainsi que l'apparition de fibrose et d'inflammation. Le choc septique est considéré comme une IC aigue particulièrement violente. Le deuxième axe de ma thèse a été de développer des modèles pertinents de choc septique et d’évaluer le potentiel thérapeutique d’une modification post-traductionnelle : la O-GlcNAcylation, déjà connue pour ses effets bénéfiques dans des formes d’IC aigues. Ainsi, une augmentation des niveaux de l'O-GlcNAc, grâce à un agent pharmacologique, le NButGT, améliore la fonction cardiovasculaire et la survie des animaux en choc septique.
Heart failure (HF) affects 1-2% of adults in developed countries. There are two distinct forms of HF: chronic HF, with a slow development, and acute HF that appears rapidly or is due to an aggravation of the symptoms and/or signs of HF. For some forms of HF, acute or chronic, no effective treatment exists. Heart failure with preserved ejection fraction (HFpEF) is becoming the predominant form of chronic HF but the understanding of its pathophysiology remains incomplete. A transgenic rat model over-expressing the human endothelial β3-adrenergic receptor has been developed in the team. As in patients, this model develops HFpEF with age, and is characterized by diastolic dysfunction and stress intolerance. During my thesis and based on transcriptome data, I evaluated alterations of the calcium cycle, metabolism as well as the appearance of fibrosis and inflammation. Septic shock is considered to be a form of severe acute HF. The second axis of my thesis was to develop relevant models of septic shock and to evaluate the therapeutic potential of a post-translational modification: O-GlcNAcylation, already known for its beneficial effects in acute HF forms. Indeed, an increase in levels of O-GlcNAc, through a pharmacological agent, NButGT, improved cardiovascular function and survival of animals in septic shock.
Advisors/Committee Members: Gauthier-Erfanian, Chantal (thesis director), Lauzier, Benjamin (thesis director).
Subjects/Keywords: O-GlcNAc
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Ferron, M. (2017). Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock. (Doctoral Dissertation). Nantes. Retrieved from http://www.theses.fr/2017NANT1046
Chicago Manual of Style (16th Edition):
Ferron, Marine. “Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock.” 2017. Doctoral Dissertation, Nantes. Accessed January 26, 2021.
http://www.theses.fr/2017NANT1046.
MLA Handbook (7th Edition):
Ferron, Marine. “Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock.” 2017. Web. 26 Jan 2021.
Vancouver:
Ferron M. Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock. [Internet] [Doctoral dissertation]. Nantes; 2017. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2017NANT1046.
Council of Science Editors:
Ferron M. Identification de nouvelles cibles thérapeutique dans l'insuffisance cardiaque à fraction d'éjection préservée et le choc septique : Identification of new therapeutic targets for heart failure with preserved ejection fraction and septic shock. [Doctoral Dissertation]. Nantes; 2017. Available from: http://www.theses.fr/2017NANT1046

Tampereen ammattikorkeakoulu
10.
Matikka, Teemu.
I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet.
Degree: 2018, Tampereen ammattikorkeakoulu
URL: http://www.theseus.fi/handle/10024/157983
► Tämä opinnäytetyön aihe on I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet. Työ tehtiin Valmet Automationille. I/O-liitynnät, I/O-laitteet ja kenttäväyliin liitetyt laitteet muodostavat Valmetin automaatiotoimitusten laitekokonaisuudet. Testausohjeiden…
(more)
▼ Tämä opinnäytetyön aihe on I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet. Työ tehtiin Valmet Automationille. I/O-liitynnät, I/O-laitteet ja kenttäväyliin liitetyt laitteet muodostavat Valmetin automaatiotoimitusten laitekokonaisuudet. Testausohjeiden tarkoitus on toimia yleisesti kattavina ohjeina tyypillisimmille projektitoimituksille. Laitteiston perusteellinen testaus on olennainen osa Valmetin projektin toimitusprosessia. Testausohjeilla pyritään tehostamaan laitteiston testausprosessia, ja varmistamaan turvallisuus.
Testaus tapahtuu kahdessa vaiheessa. Laitteistolle tehdään ensin tehdaskoestus Valmetin toimitiloissa. Laitteiston tehtaaseen asennuksen jälkeen suoritetaan käyttöönottotestaus. Tämä opinnäytetyö sisältää testausohjeet projektin molempiin vaiheisiin. Testausohjeiden laatimiseksi seurattiin usean projektin tehdaskoestusta ja yhden projektin käyttöönottotestausta.
Tuotetut testausohjeet ovat salassapidettäviä, ja ne jäävät Valmetin käyttöön. Opinnäytetyö ei sisällä testausohjeita. Tämän opinnäytetyön julkaistavassa raporttiosiossa käsitellään testausohjeiden tekoprosessi ja testausohjeiden sisältö yleisesti. Työhön kuuluu myös sähkötyöturvallisuuden huomioiminen tehdaskoestuksessa ja käyttöönotossa. Sähkötyöturvallisuuden varmistaminen huomioitiin testausohjeissa, ja sähkötyöturvallisuutta käsitellään raporttiosiossa. EU:n konedirektiivin ja siihen liittyvien standardien vaatimukset ovat myös osa tätä työtä. Direktiivin vaatimukset ohjasivat testausohjeiden laatimista, ja opinnäytetyöhön sisältyy direktiivissä käsitelty vikatilanneanalyysi.
The topic of this thesis is Testing manuals for I/O interfaces and devices connected to fieldbus. Thesis was produced for Valmet Automation. Hardware of automation systems delivered by Valmet consists of I/O interfaces, I/O devices and devices connected to fieldbus. The purpose for testing manuals is to serve as universally comprehensive instructions for typical projects delivered by Valmet. Thorough testing of the hardware is essential part of the project delivery process of Valmet. Testing manuals aim at optimizing and securing the testing process of the hardware.
Testing is done in two parts. At first, factory acceptance testing is done in facility of Valmet. Site acceptance testing is done after hardware has been installed in factory. This thesis includes testing manuals for the both phases of testing. Factory acceptance testing of several projects and site acceptance testing of one project were observed to produce testing manuals.
Produced testing manuals are confidential and remain in the use of Valmet. Process of producing testing manuals and general content is included in published report of this thesis. Part of thesis was also electrical work safety in factory acceptance testing and deployment. Ensuring electrical work safety was acknowledged in testing manuals and electrical work safety is covered in report. Part of this thesis are also requirements of the European Union machinery directive and standards related…
Advisors/Committee Members: Tampereen ammattikorkeakoulu.
Subjects/Keywords: I/O
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Matikka, T. (2018). I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet. (Thesis). Tampereen ammattikorkeakoulu. Retrieved from http://www.theseus.fi/handle/10024/157983
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Matikka, Teemu. “I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet.” 2018. Thesis, Tampereen ammattikorkeakoulu. Accessed January 26, 2021.
http://www.theseus.fi/handle/10024/157983.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Matikka, Teemu. “I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet.” 2018. Web. 26 Jan 2021.
Vancouver:
Matikka T. I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet. [Internet] [Thesis]. Tampereen ammattikorkeakoulu; 2018. [cited 2021 Jan 26].
Available from: http://www.theseus.fi/handle/10024/157983.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Matikka T. I/O-liityntöjen ja kenttäväyliin liitettyjen laitteiden testausohjeet. [Thesis]. Tampereen ammattikorkeakoulu; 2018. Available from: http://www.theseus.fi/handle/10024/157983
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
11.
Mehdy, Ali.
Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism.
Degree: Docteur es, Sciences de la Vie et de la Santé, 2011, Université Lille I – Sciences et Technologies
URL: http://www.theses.fr/2011LIL10121
► Les Oligosaccharides soluble (OS) sont essentiellement générés durant le processus de dégradation des N-glycoprotéines nouvellement synthétisées et mal conformées (ERAD) et durant la voie «…
(more)
▼ Les Oligosaccharides soluble (OS) sont essentiellement générés durant le processus de dégradation des N-glycoprotéines nouvellement synthétisées et mal conformées (ERAD) et durant la voie « turn-over » des glycoprotéines matures. Dans le but de déterminer si la modification post-traductionnelle O-GlcNAc est effectivement impliquée dans le processus de dégradation des N-glycoprotéines, nous avons analysé par spectrométrie de masse les OS provenant des cellules CHO après traitement par l’inhibiteur PUGNAc. Le PUGNAc ou « O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbanate » est un inhibiteur puissant de l’O-GlcNAcase (OGA) qui catalyse l’hydrolyse du résidu O-GlcNAc des résidus sérine et thréonine des protéines O-GlcNAcylées.L’analyse par spectrométrie de masse révèle l’apparition d’une population d’OS de structures anormaux dans les cellules CHO suite au traitement par le PUGNAc. Cette population a été identifiée comme ayant des structures possédant des résidus GlcNAc au niveau de leur extrémité non-réductrice issues d’une dégradation lysosomale incomplète des glycoprotéines. Contrairement au PUGNAc, le NButGT, un autre inhibiteur de l’OGA, n’aboutit pas à l’apparition de cette population. Ainsi, Nous avons démontré que ces structures s’accumulent exclusivement dans la fraction membranaire conséquence de l’inhibition des β-hexosaminidases lysosomaux par le PUGNAc. Notre étude avait permis, d’un part, de mettre en évidence la capacité du PUGNAc de mimer une maladie de surcharge lysosomale et, d’autre part, de montrer un autre aspect des effets indésirables induits par le PUGNAc et qui nécessite d’être pris en considération lors de l’utilisation de cet inhibiteur.
Free oligosaccharides (fOS) are generated as a result of glycoproteins catabolism that occurs in two principal distinct pathways: the endoplasmic reticulum-associated degradation (ERAD) of misfolded newly synthesized N-glycoproteins and the mature N-glycoproteins turnover pathway. We analyzed fOS by Mass spectrometry in PUGNAc CHO treated cells in order to investigate whether O-GlcNAc modified proteins were involved in N-glycoprotein degradation process. The O-(2-acetamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbanate (PUGNAc) is a potent inhibitor of the O-GlcNAcase (OGA) catalyzing the cleavage of β-O-linked 2-acetamido-2-deoxy-beta-D-glucopyranoside (O-GlcNAc) from serine and threonine residues of post-translationally modified proteins. Mass spectrometry (MS) analysis revealed the appearance of an unusual population of fOS after PUGNAc treatment. The structures representing this population have been identified as containing non-reducing end GlcNAc residues resulting from incomplete lysosomal fOS degradation. Only observed after PUGNAc treatment, the NButGt, another OGA inhibitor, did not lead to the appearance of the population. These structures have clearly been shown to accumulate in membrane fractions as the consequence of lysosomal β-hexosaminidases inhibition by PUGNAc. As Lysosomal Storage Disorders (LSD) are…
Advisors/Committee Members: Foulquier, François (thesis director), Duvet, Sandrine (thesis director).
Subjects/Keywords: O-GlcNAc; O-GlcNAcase – Inhibiteurs; 572.68
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Record Details
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mehdy, A. (2011). Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2011LIL10121
Chicago Manual of Style (16th Edition):
Mehdy, Ali. “Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism.” 2011. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 26, 2021.
http://www.theses.fr/2011LIL10121.
MLA Handbook (7th Edition):
Mehdy, Ali. “Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism.” 2011. Web. 26 Jan 2021.
Vancouver:
Mehdy A. Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2011. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2011LIL10121.
Council of Science Editors:
Mehdy A. Impact du PUGNAc sur le catabolisme des N-glycoprotéines : Impact of PUGNAc on N-glycoproteins catabolism. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2011. Available from: http://www.theses.fr/2011LIL10121

University of Guelph
12.
Hunt, Brittany.
Investigation of the Expression of the O:54 antigen from Salmonella enterica.
Degree: MS, Department of Molecular and Cellular Biology, 2013, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7624
► WbbF is a proposed member of the synthase family of dual glycosyltransferase-exporter proteins. WbbF assembles the O:54 antigen from Salmonella enterica. The wb*O:54 operon (encoding…
(more)
▼ WbbF is a proposed member of the synthase family of dual glycosyltransferase-exporter proteins. WbbF assembles the
O:54 antigen from Salmonella enterica. The wb*
O:54 operon (encoding wbbE, wbbF and mnaA) is found on a naturally-occuring plasmid (pWQ799). Previous research suggested only WbbE and WbbF are necessary for
O:54 antigen assembly due to the presence of a chromosomal gene encoding WecB, a functional homolog of MnaA. WecB and MnaA synthesize the essential UDP-ManNAc donor. However, this study determined optimal production of
O:54 in E. coli was dependent on the presence of MnaA. A growth defect was observed in cells producing
O:54 antigen, but unable to ligate it to the lipopolysaccharide acceptor (due to ΔwaaL). Cells recovered growth over time via mutations that turned off (or down)
O:54 antigen biosynthesis. During this study, a cysteine-free version of WbbF that retained function was established, providing a key resource for future topology mapping experiments.
Advisors/Committee Members: Whitfield, Chris (advisor).
Subjects/Keywords: O-antigen; lipopolysaccharide; synthase; O:54; WbbF
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APA (6th Edition):
Hunt, B. (2013). Investigation of the Expression of the O:54 antigen from Salmonella enterica. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7624
Chicago Manual of Style (16th Edition):
Hunt, Brittany. “Investigation of the Expression of the O:54 antigen from Salmonella enterica.” 2013. Masters Thesis, University of Guelph. Accessed January 26, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7624.
MLA Handbook (7th Edition):
Hunt, Brittany. “Investigation of the Expression of the O:54 antigen from Salmonella enterica.” 2013. Web. 26 Jan 2021.
Vancouver:
Hunt B. Investigation of the Expression of the O:54 antigen from Salmonella enterica. [Internet] [Masters thesis]. University of Guelph; 2013. [cited 2021 Jan 26].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7624.
Council of Science Editors:
Hunt B. Investigation of the Expression of the O:54 antigen from Salmonella enterica. [Masters Thesis]. University of Guelph; 2013. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7624

University of Georgia
13.
El-Katri, Fares A.
Photochemical generation & hydration of isomeric naphthaquinone methides.
Degree: 2014, University of Georgia
URL: http://hdl.handle.net/10724/23106
► The ortho-quinone methides (o-QMs) are potentially very important intermediates in organic and biochemistry. This work is a contribution to th e chemistry of the o-QMs.…
(more)
▼ The ortho-quinone methides (o-QMs) are potentially very important intermediates in organic and biochemistry. This work is a contribution to th e chemistry of the o-QMs. Different ways to produce o-QMs are explored. The focus in this work is
on the photogeneration of the ortho- naphthaquinone methide isomers with possible sp ectroscopic and kinetic investigation for their hydration back to their synthetic precursors.
Subjects/Keywords: o-quinone methides; methides; o-naphthaquinone methides
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
El-Katri, F. A. (2014). Photochemical generation & hydration of isomeric naphthaquinone methides. (Thesis). University of Georgia. Retrieved from http://hdl.handle.net/10724/23106
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
El-Katri, Fares A. “Photochemical generation & hydration of isomeric naphthaquinone methides.” 2014. Thesis, University of Georgia. Accessed January 26, 2021.
http://hdl.handle.net/10724/23106.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
El-Katri, Fares A. “Photochemical generation & hydration of isomeric naphthaquinone methides.” 2014. Web. 26 Jan 2021.
Vancouver:
El-Katri FA. Photochemical generation & hydration of isomeric naphthaquinone methides. [Internet] [Thesis]. University of Georgia; 2014. [cited 2021 Jan 26].
Available from: http://hdl.handle.net/10724/23106.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
El-Katri FA. Photochemical generation & hydration of isomeric naphthaquinone methides. [Thesis]. University of Georgia; 2014. Available from: http://hdl.handle.net/10724/23106
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
14.
Fleurence, Julien.
Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform.
Degree: Docteur es, Recherche clinique, innovation thérapeutique, santé publique, 2017, Nantes
URL: http://www.theses.fr/2017NANT1007
► Le glioblastome multiforme (GBM) est la tumeur cérébrale maligne la plus fréquente et la plus agressive chez l’adulte. Malgré l’utilisation concomitante de la chirurgie avec…
(more)
▼ Le glioblastome multiforme (GBM) est la tumeur cérébrale maligne la plus fréquente et la plus agressive chez l’adulte. Malgré l’utilisation concomitante de la chirurgie avec la radiothérapie et la chimiothérapie (protocole de Stupp), le pronostic des patients reste sombre avec un taux de survie à 5 ans inférieur à 10 %. La présence de cellules souches cancéreuses (CSC) favorise le maintien de la tumeur puis l’échappement tumoral responsable de la rechute des patients. Il est donc nécessaire d’identifier de nouvelles cibles thérapeutiques pour améliorer la prise en charge de ces patients. Dans ce contexte, l’immunothérapie, stratégie utilisant le système immunitaire pour traiter le cancer, représente une voie prometteuse.Nous identifions ici le OAcGD2 comme un nouvel antigène tumoral du GBM et a partir de biopsie tumorale provenant d’une cohorte de 37 patients. L’utilisation de primoculture de GBM nous permet de plus de démontrer que ce marqueur est également exprimé par les cellules souches de GBM. Nous apportons la preuve de concept de l’immunothérapie du GBM à l’aide d’anticorps monoclonaux anti-OAcGD2 in vitro et in vivo. A côté de la cytotoxicté immunologique, nous identifions un nouveau mécanisme de mort programmé, l’oncose, mis en jeu par les AcM anti-OAcGD2 permettant de sensibiliser ces cellules aux agents de chimiothérapie comme le témolozomide. L’utilisation de l’immunothérapie ciblant le marqueur gangliosidique tumoral OAcGD2 pourrait ainsi permettre d’améliorer l’efficacité de la thérapeutique actuelle (protocole de Stupp) du GBM
Glioblastoma multiforme (GBM) is the most common and agressive primary brain tumors in adults. Despite the concomitant use of surgery with radiotherapy and chemotherapy, the prognosis of patients remains extremely low. The presence of cancer stem cells (CSC) promotes the maintenance of the tumor and then the tumor escape responsible for the relapse of the patients. Therefore it is necessary to identify new therapeutic targets to improve the management of these patients. In the past few decades, immunotherapy represents an important part of treating certain type of cancer. It uses the immune system to treat cancer. Here, we found that O-acetyl GD2 (OAcGD2) is expressed in surgically resected human glioblastoma tissue. In addition, we demonstrated that 8B6 monoclonal antibody specific for OAcGD2 could effectively inhibit glioblastoma cell proliferation in vitro and in vivo. Mostly, we found that OAcGD2 was expressed on the GBM stem cells. We also observed that mAb 8B6 promoted the elimination of GBM via a oncosis-like mechanism. Moreover, this mechanism of programmed cell death induced by anti-OAcGD2 mAbs, sensitizes GBM cells and CSCs to chemotherapy agents such as temolozomide (TMZ). Taken together, these results indicate that O-acetylated GD2 represents a novel antigen for immunotherapeutic-based treatment of high-grade gliomas, and that anti-OAcGD2 mAbs combined with TMZ could enhance therapeutic response in GBM.
Advisors/Committee Members: Birklé, Stéphane (thesis director), Paris, François (thesis director).
Subjects/Keywords: GD2-O-acétylé
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Fleurence, J. (2017). Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform. (Doctoral Dissertation). Nantes. Retrieved from http://www.theses.fr/2017NANT1007
Chicago Manual of Style (16th Edition):
Fleurence, Julien. “Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform.” 2017. Doctoral Dissertation, Nantes. Accessed January 26, 2021.
http://www.theses.fr/2017NANT1007.
MLA Handbook (7th Edition):
Fleurence, Julien. “Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform.” 2017. Web. 26 Jan 2021.
Vancouver:
Fleurence J. Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform. [Internet] [Doctoral dissertation]. Nantes; 2017. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2017NANT1007.
Council of Science Editors:
Fleurence J. Ciblage du GD2-O-acétylé par un anticorps monoclonal dans le glioblastome multiforme : Targeting of GD2-O-acetylated by monoclonal antibody in glioblastoma multiform. [Doctoral Dissertation]. Nantes; 2017. Available from: http://www.theses.fr/2017NANT1007

San Jose State University
15.
Mercado, Juan Pablo.
Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation.
Degree: MA, Mexican American Studies, 2011, San Jose State University
URL: https://doi.org/10.31979/etd.r8d3-w7yc
;
https://scholarworks.sjsu.edu/etd_projects/192
► Traditional U.S. historical scholars, as a matter of practice, carelessly push the history of the Mexican American community to the fringes of the collective…
(more)
▼ Traditional U.S. historical scholars, as a matter of practice, carelessly push the history of the Mexican American community to the fringes of the collective historical consciousness of this country by selecting the common stories that students of all races learn. This study examines the problem of insufficient and inadequate historical scholarship pertaining to people of Mexican ancestry of the United States. By providing a local history of Mexican Americans in the Sacramento Valley this project provides a challenge to the legacy of historical exclusion by documenting the contributions and experiences of the Mexican American World War II generation and provides an alternative historical perspective to the World War II narrative.
Advisors/Committee Members: Gregorio Mora Torres, Julia E. Curry Rodríguez.
Subjects/Keywords: Chicana/o Studies
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Mercado, J. P. (2011). Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation. (Masters Thesis). San Jose State University. Retrieved from https://doi.org/10.31979/etd.r8d3-w7yc ; https://scholarworks.sjsu.edu/etd_projects/192
Chicago Manual of Style (16th Edition):
Mercado, Juan Pablo. “Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation.” 2011. Masters Thesis, San Jose State University. Accessed January 26, 2021.
https://doi.org/10.31979/etd.r8d3-w7yc ; https://scholarworks.sjsu.edu/etd_projects/192.
MLA Handbook (7th Edition):
Mercado, Juan Pablo. “Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation.” 2011. Web. 26 Jan 2021.
Vancouver:
Mercado JP. Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation. [Internet] [Masters thesis]. San Jose State University; 2011. [cited 2021 Jan 26].
Available from: https://doi.org/10.31979/etd.r8d3-w7yc ; https://scholarworks.sjsu.edu/etd_projects/192.
Council of Science Editors:
Mercado JP. Re-envisioning the Mexican American Experience in World War II: A Local History of Sacramento & the Mexican American WWII Generation. [Masters Thesis]. San Jose State University; 2011. Available from: https://doi.org/10.31979/etd.r8d3-w7yc ; https://scholarworks.sjsu.edu/etd_projects/192
16.
Pérez-Cervera, Yobana.
Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation".
Degree: Docteur es, Sciences de la vie et de la santé, 2012, Université Lille I – Sciences et Technologies
URL: http://www.theses.fr/2012LIL10105
► La O-GlcNAcylation est une modification post-traductionnelle appartenant au groupe des glycosylations. C’est une modification dynamique, analogue à la phosphorylation, dont la réversibilité est contrôlée par…
(more)
▼ La O-GlcNAcylation est une modification post-traductionnelle appartenant au groupe des glycosylations. C’est une modification dynamique, analogue à la phosphorylation, dont la réversibilité est contrôlée par un couple d’enzymes, la O-GlcNAc transférase (OGT) et la O-GlcNAcase (OGA). Bien que les fonctions de la O-GlcNAcylation aient été étudiées à différents niveaux de régulation cellulaire, aucune étude n’a porté jusqu’ici sur sa localisation potentielle au niveau des radeaux lipidiques (rafts). Or, il a été récemment démontré que l’élévation des niveaux de O-GlcNAcylation participait activement au phénomène de résistance à l’insuline et un nombre important de preuves a également été apporté sur le rôle critique des microdomaines lipidiques dans ce phénomène de résistance. On sait également depuis peu qu’après stimulation par l'insuline, l’OGT est recrutée à la membrane plasmique par l'intermédiaire de son domaine PPO (PIP-binding activity of OGT), et que cette relocalisation inactive la voie de signalisation PI3-kinase/Akt par antagonisme vis-à-vis de la phosphorylation. Ces trois observations suggèrent que l’OGT puisse constituer un relai essentiel permettant de transmettre l’information portée par des stimuli externes au travers de la membrane plasmique, et plus particulièrement des rafts, par le biais d’une régulation des voies de signalisation. Au cours de ma thèse, nous avons adapté une technique permettant de purifier les microdomaines lipidiques, en procédant par une extraction par le détergent CHAPSO suivi d'une étape d'ultracentrifugation. Nos expériences ont montré pour la première fois la localisation de l’OGT et de protéines O-GlcNAcylées, parmi lesquelles nous avons identifié la chaîne bêta du récepteur de l'insuline et Hsp70, au niveau des microdomaines lipidiques. Le recrutement de ces éléments est contrôlé par l’insuline: nous avons en effet observé une association progressive de la glycosyltransférase aux microdomaines lipidiques après stimulation par cette hormone. Nous avons démontré que, en réponse à l'insuline, l’OGT est recrutée au niveau des lipides rafts, ce qui suggère une régulation négative de la voie PI3-Kinase/Akt par O-GlcNAcylation, au niveau des microdomaines lipidiques. Cette étude est la première suggérant une relation directe entre la O-GlcNAcylation des protéines associées aux rafts et la régulation de la signalisation cellulaire par l'insuline. En marge de ses travaux, nous avons mis en évidence l'existence de la O-GlcNAcylation chez les deux parasites apicomplexes Toxoplasma gondii et Plasmodium falciparum. Une approche biochimique et bioinformatique a également permis de prouver l'existence propre de l'OGT chez le toxoplasme.
The attachment of O-linked beta-N-acetylglucosamine (O-GlcNAc) to proteins is a post-translational modification belonging to the group of glycosylations. This is a dynamic modification, analogous to phosphorylation, which reversibility is controlled by a couple of enzymes, namely the O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Although the…
Advisors/Committee Members: Lefebvre, Tony (thesis director).
Subjects/Keywords: O-GlcNAcylation; 572.68
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Pérez-Cervera, Y. (2012). Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation". (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2012LIL10105
Chicago Manual of Style (16th Edition):
Pérez-Cervera, Yobana. “Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation".” 2012. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 26, 2021.
http://www.theses.fr/2012LIL10105.
MLA Handbook (7th Edition):
Pérez-Cervera, Yobana. “Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation".” 2012. Web. 26 Jan 2021.
Vancouver:
Pérez-Cervera Y. Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation". [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2012. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2012LIL10105.
Council of Science Editors:
Pérez-Cervera Y. Etude des relations "O-GlcNAcylation et microdomaines lipidiques" : Study of relationship "lipid microdomaines and O-GlcNAcylation". [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2012. Available from: http://www.theses.fr/2012LIL10105

University of Otago
17.
McKenzie, Katherine.
Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
.
Degree: 2012, University of Otago
URL: http://hdl.handle.net/10523/2319
► The purpose of this study was to investigate the increasing importance of person-organisation fit in organisations and how this might be attained during the recruitment…
(more)
▼ The purpose of this study was to investigate the increasing importance of person-organisation fit in organisations and how this might be attained during the recruitment and selection process. It achieved this aim by examining Schneider’s (1987) attraction-selection-attrition model within a graduate recruitment context. Three stakeholder perspectives were studied – job seekers, recruiters and employees – with each perspective assigned to one element of the model.
The study consisted of three distinct parts. First, an online survey was completed by 137 university students to understand the ‘attraction’ element of the model, and to gauge the importance placed on person-organisation fit by job seekers. Second, 26 graduate recruiters were surveyed, and a further seven interviewed, to ascertain the emphasis placed on person-organisation fit during the ‘selection’ phase, and to gain an understanding of how ‘fit’ is assessed. Finally, ‘attrition’ to the firm was explored by surveying graduates and measuring the level of values congruence obtained with their employing organisation.
The results revealed that although job seekers do consciously assess the values of the organisations to which they apply, person-organisation fit was not found to be of much importance to them. Instead, self-selection was based upon more tangible elements, such as reputation, of a firm. On the other hand, it was found that person-organisation fit has become a prevailing feature of the graduate selection process, with organisations spending a large percentage of time evaluating a candidate’s ‘fit’ to the firm rather than their ‘fit’ to the specific requirements of the job. Person-organisation fit was typically assessed during in-person interactions, with recruiters evaluating a range of behavioural competencies that related back to the firm’s core values. This study also revealed a low level of values congruence (i.e. person-organisation fit) is actually achieved in the appointment of university graduates. Overall, support for the attraction-selection-attrition framework is not found, as person-organisation fit appears to be neither of great importance to job seekers, nor is a high level of ‘fit’ attained in the recruitment and selection of graduates.
Advisors/Committee Members: Edgar, Fiona (advisor).
Subjects/Keywords: P-O Fit
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APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
McKenzie, K. (2012). Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
. (Masters Thesis). University of Otago. Retrieved from http://hdl.handle.net/10523/2319
Chicago Manual of Style (16th Edition):
McKenzie, Katherine. “Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
.” 2012. Masters Thesis, University of Otago. Accessed January 26, 2021.
http://hdl.handle.net/10523/2319.
MLA Handbook (7th Edition):
McKenzie, Katherine. “Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
.” 2012. Web. 26 Jan 2021.
Vancouver:
McKenzie K. Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
. [Internet] [Masters thesis]. University of Otago; 2012. [cited 2021 Jan 26].
Available from: http://hdl.handle.net/10523/2319.
Council of Science Editors:
McKenzie K. Enhancing Person-Organization Fit: An investigation into the recruitment and selection of university graduates
. [Masters Thesis]. University of Otago; 2012. Available from: http://hdl.handle.net/10523/2319
18.
สุขเอก, พิชิตชัย.
การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
.
Degree: คณะศึกษาศาสตร์ ภาควิชาประเมินผลและวิจัยทางการศึกษา, Prince of Songkla University
URL: http://kb.psu.ac.th/psukb/handle/2016/11839
► การวิจัยครั้งนี้ มีวัตถุประสงค์เพื่อวิเคราะห์คุณภาพแบบทดสอบการทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน (O-NET) และตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค (Multiple Indicators and Multiple Causes : MIMIC) เมื่อจำแนกตามเพศและที่ตั้งของสถานศึกษา ระหว่างปีการศึกษา 2556 – 2558 ประชากรที่ใช้ในการวิจัยครั้งนี้เป็นนักเรียนชั้นมัธยมศึกษาปีที่ 6 เครื่องมือที่ใช้ในการวิจัยคือแบบทดสอบการทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน (O-NET) ชั้นมัธยมศึกษาปีที่ 6 ปีการศึกษา 2556 –…
(more)
▼ การวิจัยครั้งนี้ มีวัตถุประสงค์เพื่อวิเคราะห์คุณภาพแบบทดสอบการทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน (
O-NET) และตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค (Multiple Indicators and Multiple Causes : MIMIC) เมื่อจำแนกตามเพศและที่ตั้งของสถานศึกษา ระหว่างปีการศึกษา 2556 – 2558 ประชากรที่ใช้ในการวิจัยครั้งนี้เป็นนักเรียนชั้นมัธยมศึกษาปีที่ 6 เครื่องมือที่ใช้ในการวิจัยคือแบบทดสอบการทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน (
O-NET) ชั้นมัธยมศึกษาปีที่ 6 ปีการศึกษา 2556 – 2558 โดยมีรายวิชาภาษาไทย ภาษาอังกฤษ คณิตศาสตร์ และวิทยาศาสตร์ ซึ่งเป็นข้อมูลทุติยภูมิ ผลการวิจัยพบว่า
1. ผลการประมาณค่าพารามิเตอร์ความยาก อำนาจจำแนกของข้อสอบ และระดับความสามารถของผู้สอบของแบบทดสอบการทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน (
O-NET) ปีการศึกษา 2556 – 2558 พบว่ารายวิชาภาษาไทย มีค่าความยากน้อยสุดเท่ากับ .01 และสูงสุดเท่ากับ 8.32 ค่าอำนาจจำแนกน้อยสุดเท่ากับ .01 และสูงสุดเท่ากับ 1.03 ค่าความสามารถของผู้สอบน้อยสุด -3.73 และสูงสุดเท่ากับ 3.41 รายวิชาภาษาอังกฤษ มีค่าความยากน้อยสุดเท่ากับ .00 และสูงสุดเท่ากับ 8.31 ค่าอำนาจจำแนกน้อยสุดเท่ากับ .00 และสูงสุดเท่ากับ 1.18 ค่าความสามารถของผู้สอบน้อยสุด -2.83 และสูงสุดเท่ากับ 5.05 รายวิชาคณิตศาสตร์ มีค่าความยากน้อยสุดเท่ากับ .05 และสูงสุดเท่ากับ 8.14 ค่าอำนาจจำแนกน้อยสุดเท่ากับ .02 และสูงสุดเท่ากับ .70 ค่าความสามารถของผู้สอบน้อยสุด -2.11 และสูงสุดเท่ากับ 3.90 รายวิชาวิทยาศาสตร์ มีค่าความยากน้อยสุดเท่ากับ -82.66 และสูงสุดเท่ากับ 494.63 ค่าอำนาจจำแนกน้อยสุดเท่ากับ -1.09 และสูงสุดเท่ากับ 1.18 ความสามารถของผู้สอบน้อยสุด -2.74 และสูงสุดเท่ากับ 4.75
2. ผลการตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค จำแนกตามเพศ พบว่ารายวิชาภาษาไทยและวิทยาศาสตร์ เพศชายมีโอกาสตอบข้อสอบถูกมากกว่าเพศหญิง และรายวิชาภาษาอังกฤษ เพศหญิงมีโอกาสตอบข้อสอบถูกมากกว่าเพศชาย เมื่อจำแนกตามที่ตั้งของสถานศึกษา พบว่ารายวิชาภาษาไทย และภาษาอังกฤษ ที่ตั้งของสถานศึกษาในเมืองมีโอกาสตอบข้อสอบถูกมากกว่านอกเมือง และรายวิชาคณิตศาสตร์และวิทยาศาสตร์ ที่ตั้งของสถานศึกษานอกเมืองมีโอกาสตอบข้อสอบถูกมากกว่าในเมือง
The objective of this research were to check test quality analysis of Ordinary National Educational Test (
O-NET) and Differential Item Functioning (DIF) by using Multiple Indicators and Multiple Causes (MIMIC) when distinguish by genders and school locations, during 2013-2015 academic years. Parameters that used in this research were grade 12 students by using multistage stage sampling. The research instrument was test of Ordinary National Educational Test (
O-NET) grade 12 students, 2013-2015 academic years, including Thai, English Mathematics and Sciences that were minor information. This research found that
1. Analysis of Parameter of Difficulty, Test Discrimination and Ability Parameters of Ordinary National Educational Test (
O-NET), during 2013-2015 academic years revealed that Thai had the fewest difficulty was .01 and the highest difficulty was 8.32, the fewest test discrimination was .01 and the highest test discrimination was 1.03, the fewest ability parameters was -3.73 and the highest ability parameters was 3.41. English had the fewest difficulty was .00 and the highest difficulty was 8.31 ,the…
Advisors/Committee Members: ตันสกุล, จิระวัฒน์ (advisor).
Subjects/Keywords: การทดสอบทางการศึกษาระดับชาติขั้นพื้นฐาน;
O-NET
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APA (6th Edition):
สุขเอก, . (n.d.). การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
. (Thesis). Prince of Songkla University. Retrieved from http://kb.psu.ac.th/psukb/handle/2016/11839
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
สุขเอก, พิชิตชัย. “การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
.” Thesis, Prince of Songkla University. Accessed January 26, 2021.
http://kb.psu.ac.th/psukb/handle/2016/11839.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
สุขเอก, พิชิตชัย. “การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
.” Web. 26 Jan 2021.
Note: this citation may be lacking information needed for this citation format:
No year of publication.
Vancouver:
สุขเอก . การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
. [Internet] [Thesis]. Prince of Songkla University; [cited 2021 Jan 26].
Available from: http://kb.psu.ac.th/psukb/handle/2016/11839.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.
Council of Science Editors:
สุขเอก . การตรวจสอบการทำหน้าที่ต่างกันของข้อสอบโดยใช้วิธีมิมิค
. [Thesis]. Prince of Songkla University; Available from: http://kb.psu.ac.th/psukb/handle/2016/11839
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
No year of publication.

University of Guelph
19.
Moynihan, Patrick J.
Biochemical Characterization of Peptidoglycan O-Acetyltransferases.
Degree: PhD, Department of Molecular and Cellular Biology, 2014, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7759
► The O-acetylation of the essential cell wall polymer peptidoglycan is a major virulence factor identified in many bacteria, both Gram positive and Gram negative, including…
(more)
▼ The
O-acetylation of the essential cell wall polymer peptidoglycan is a major virulence factor identified in many bacteria, both Gram positive and Gram negative, including Staphylococcus aureus, Bacillus anthracis, Neisseria gonorrhoeae and N. meningitidis. With Gram-negative bacteria, the translocation of acetate from the cytoplasm is thought to be performed by an integral membrane protein, PatA. The acetate is then transferred to peptidoglycan by a peripheral membrane
O-acetyltransferase PatB, whereas a single bimodal membrane protein, OatA, appears to catalyze both reactions of the process in Gram-positive bacteria. Only phenotypic evidence existed in support of these pathways because no in vitro biochemical assay was available for their analysis, which reflected the complexities of investigating integral membrane proteins that act on a totally insoluble and heterogeneous substrate such as peptidoglycan. In this thesis, I present the first kinetic and biochemical analysis of a PG
O-acetyltransferase using PatB from N. gonorrhoeae as the model system. The enzyme has specificity for muropeptides that possess tetrapeptide stems on muramoyl residue sand with simple chitooligosaccharides as substrates, rates of reaction increase with increasing degrees of polymerization to 5/6. The data provided here strongly supports a mechanism whereby catalysis occurs by a double-displacement nucleophilic pathway involving a ping-pong bi-bi mechanism that proceeds through a covalent acetyl-serine intermediate. In addition to the catalytic serine, the aspartic acid and histidine residues that complete the catalytic triad were identified. I then applied the tools developed for the analysis of PatB to the Gram-positive
O-acetyltransferase, OatA. The preliminary characterization of the catalytic domain of that enzyme detailed in this thesis will form the basis for future high-throughput screening with the goal of identifying OatA inhibitors. This information will be valuable for the identification and development of peptidoglycan
O-acetyltransferase inhibitors, which could represent potential leads to novel classes of antibiotics. Together, these data solidify our understanding of the mechanism by which an important bacterial virulence factor is produced and pave the way for future development of novel antimicrobials.
Advisors/Committee Members: Clarke, Anthony J. (advisor).
Subjects/Keywords: peptidoglycan; O-acetylation
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moynihan, P. J. (2014). Biochemical Characterization of Peptidoglycan O-Acetyltransferases. (Doctoral Dissertation). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7759
Chicago Manual of Style (16th Edition):
Moynihan, Patrick J. “Biochemical Characterization of Peptidoglycan O-Acetyltransferases.” 2014. Doctoral Dissertation, University of Guelph. Accessed January 26, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7759.
MLA Handbook (7th Edition):
Moynihan, Patrick J. “Biochemical Characterization of Peptidoglycan O-Acetyltransferases.” 2014. Web. 26 Jan 2021.
Vancouver:
Moynihan PJ. Biochemical Characterization of Peptidoglycan O-Acetyltransferases. [Internet] [Doctoral dissertation]. University of Guelph; 2014. [cited 2021 Jan 26].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7759.
Council of Science Editors:
Moynihan PJ. Biochemical Characterization of Peptidoglycan O-Acetyltransferases. [Doctoral Dissertation]. University of Guelph; 2014. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7759

University of Guelph
20.
Sychantha, David.
Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987.
Degree: MS, Department of Molecular and Cellular Biology, 2014, University of Guelph
URL: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7771
► O-acetylation of the essential bacterial heteropolymer peptidoglycan is required for modulation of host-pathogen interactions and proper cell growth. Given this, the O- acetylation pathway is…
(more)
▼ O-acetylation of the essential bacterial heteropolymer peptidoglycan is required for modulation of host-pathogen interactions and proper cell growth. Given this, the
O- acetylation pathway is thought to present a novel drug target. Our current understanding of the enzymes involved in this process lacks the key structural information required for better identification and design of novel inhibitors. This work demonstrates the production and purification of a stable and active recombinant form of peptidoglycan
O-acetyltransferase B (PatB1) from Bacillus cereus for use in crystallization studies. The enzymatic function of PatB1 was demonstrated to be dependent on the presence of the sugar-based acetyl acceptor chitobiose, in a manner similar to PatB from Neisseria gonorrhoeae. Using a method which combines surface entropy reduction and in situ proteolysis, single crystals of PatB1 were produced in sparse matrix crystallization screens and diffracted to 2.0 Å resolution.
Advisors/Committee Members: Clarke, Anthony (advisor).
Subjects/Keywords: O-acetylation Peptidoglycan
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Sychantha, D. (2014). Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987. (Masters Thesis). University of Guelph. Retrieved from https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7771
Chicago Manual of Style (16th Edition):
Sychantha, David. “Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987.” 2014. Masters Thesis, University of Guelph. Accessed January 26, 2021.
https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7771.
MLA Handbook (7th Edition):
Sychantha, David. “Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987.” 2014. Web. 26 Jan 2021.
Vancouver:
Sychantha D. Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987. [Internet] [Masters thesis]. University of Guelph; 2014. [cited 2021 Jan 26].
Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7771.
Council of Science Editors:
Sychantha D. Crystallization of Peptidoglycan O-acetyltransferase B from Bacillus cereus 10987. [Masters Thesis]. University of Guelph; 2014. Available from: https://atrium.lib.uoguelph.ca/xmlui/handle/10214/7771
21.
Biwi, James Tapiwa.
Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines.
Degree: Docteur es, Biomolécules, pharmacologie, thérapeutique, 2019, Université Lille I – Sciences et Technologies
URL: http://www.theses.fr/2019LIL1S104
► Le cancer colorectal (CCR) est une pathologie dont les causes tiennent en partie d’un style de vie basé sur un régime alimentaire de type occidental…
(more)
▼ Le cancer colorectal (CCR) est une pathologie dont les causes tiennent en partie d’un style de vie basé sur un régime alimentaire de type occidental et un mode de vie sédentaire. Cela implique par conséquent que le CCR soit associé à d’autres troubles métaboliques tels que l’obésité et le diabète. D’un consensus général on considère que le CCR est une maladie qui est mieux traitée si elle est dépistée relativement tôt ; malheureusement il n’existe toujours pas d’outils de diagnostic suffisamment fiables. A ce propos, différents types de glycosylation ont été proposés comme de potentiels biomarqueurs de cette maladie. Les travaux abordés dans cette thèse ont concerné l'influence de la
O-GlcNAcylation (consistant en le transfert d'un seul monosaccharide de N-acétylglucosamine sur des résidus de sérine/thréonine de protéines cytoplasmiques, nucléaires et mitochondriales), sur la glycosylation complexe dans des lignées cellulaires coliques (HT29, HCT116 et CCD841CoN). La
O-GlcNAcylation est intimement liée au statut nutritionnel, il est d’ailleurs proposé que son niveau soit plus élevé dans les pathologies métaboliques. Néanmoins il est clairement montré que les cellules et les tumeurs coliques expriment des niveaux plus élevés de
O-GlcNAcylation. Plusieurs études ont montré que l’inhibition ou la délétion de la
O-GlcNAc transférase (OGT), l’enzyme responsable des processus de
O-GlcNAcylation, réduisait l'agressivité ou les propriétés associées au caractère tumoral dans différents modèles de cancer. Quelques études ont également montré que la sous-régulation de l’OGT se répercutait sur les glycosylations complexes : N- et
O-glycanes, et glycosphingolipides (GSLs). La
O-GlcNAcylation participe à des processus cellulaires clés tels que la transcription et la traduction. Dans une étude préliminaire, nous avons examiné les niveaux de transcrits de quatre-vingt-six glycosyltransférases et glycosidases dans des conditions de siOGT. Le siOGT a permis de constater que plusieurs de ces gènes étaient régulés positivement ou négativement, bien que parmi ces gènes seuls 10 étaient régulés négativement de manière significative. L'influence de l’OGT sur l’expression protéique de plusieurs glycosyltransférases a également été explorée. Nous avons ensuite utilisé plusieurs lectines en microscopie par fluorescence et en cytométrie en flux ainsi que la spectrométrie de masse (glycomique) afin d'élucider les structures complexes des glycanes et leur niveau d’expression dans les cellules coliques traitées par des siOGT. La diminution de
O-GlcNAcylation n'a eu qu’un effet modéré sur les N- et
O-glycanes globaux. Cependant, l'expression de plusieurs antigènes de surface a été modifiée par le siOGT. La E-cadhérine, un facteur majeur de la transition épithéliale-mésenchymateuse, a été régulée positivement dans les cellules HT29 traitées par le siOGT. De plus, les glycanes complexes portés par la E-cadhérine ont été eux-mêmes modifiés dans les cellules traitées par le siOGT. L'analyse MALDI des GSLs extraits de cellules HCT116 a révélé une…
Advisors/Committee Members: Biot, Christophe (thesis director), Lefebvre, Tony (thesis director).
Subjects/Keywords: O-GlcNAcylation; 571.978
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Biwi, J. T. (2019). Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2019LIL1S104
Chicago Manual of Style (16th Edition):
Biwi, James Tapiwa. “Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines.” 2019. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 26, 2021.
http://www.theses.fr/2019LIL1S104.
MLA Handbook (7th Edition):
Biwi, James Tapiwa. “Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines.” 2019. Web. 26 Jan 2021.
Vancouver:
Biwi JT. Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2019. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2019LIL1S104.
Council of Science Editors:
Biwi JT. Nouvelles connaissances sur la régulation de la glycosylation complexe par O-GlcNAcylation dans des lignées coliques saines et cancéreuses : Novel insights on complex glycosylation regulation by O-GlcNAcylation in healthy and cancer colon cell lines. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2019. Available from: http://www.theses.fr/2019LIL1S104
22.
Fourneau, Julie.
Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation.
Degree: Docteur es, Neursciences, 2018, Université Lille I – Sciences et Technologies
URL: http://www.theses.fr/2018LIL1S105
► La sédentarité ou un alitement prolongé sont des situations ayant en commun une perturbation sensorimotrice (PSM), conduisant à une dégradation de la posture et la…
(more)
▼ La sédentarité ou un alitement prolongé sont des situations ayant en commun une perturbation sensorimotrice (PSM), conduisant à une dégradation de la posture et la locomotion, dont l’origine est à la fois musculaire et nerveuse. Des études réalisées sur un modèle animal de PSM ont notamment montré des modifications biochimiques et morphologiques au niveau du cortex sensorimoteur. Cependant, les mécanismes sous-jacents ne sont tous pas élucidés. La O-GlcNAcylation, une glycosylation atypique, est une bonne candidate pour participer à cette neuroplasticité. Par interaction avec la phosphorylation, ces modifications post-traductionnelles sont impliquées dans des processus essentiels tels que l'activité synaptique ou la morphogenèse neuronale. L’objectif principal de cette thèse a été d’étudier les mécanismes moléculaires de la plasticité synaptique du cortex sensorimoteur et d’examiner l’implication potentielle de la O-GlcNAcylation au cours d’une période de PSM. Des changements d’activation et d’expression de protéines synaptiques ont été mis en évidence, montrant une diminution de la libération des neurotransmetteurs et une réduction de l’efficacité synaptique. La O-GlcNAcylation et la phosphorylation interviennent dans ces modifications en régulant finement l’activité de protéines spécifiques. La modulation des taux corticaux de O-GlcNAcylation permet de prévenir la réorganisation du cortex somesthésique, et prévient partiellement certaines altérations des performances sensorimotrices induite par une PSM. En conclusion, ces travaux montrent que la O-GlcNAcylation, en interaction avec la phosphorylation, participe activement à la plasticité synaptique induite par une PSM.
Sensorimotor perturbation (SMP) is frequently encountered in various situations, such as a sedentary lifestyle or prolonged bed rest. They all lead to postural and locomotor issues; whose origin is both muscular and nervous. Studies performed in a SMP animal model have shown changes in the sensorimotor cortex such as biochemical changes, somatotopic maps reorganization, morphological modifications of dendritic spines…. However, the underlying mechanisms are still unclear. O-GlcNAcylation, an atypical glycosylation, is a good candidate to participate in this neuroplasticity. By interplays with phosphorylation, these posttranslational modifications are both involved in essential cellular and physiological processes such as synaptic activity or neuronal morphogenesis. The main objective of this thesis was to study the molecular mechanisms of synaptic plasticity of the sensorimotor cortex and to examine the potential involvement of O-GlcNAcylation during a SMP period. We have shown that a period of SMP induces changes in activation and expression of synaptic proteins, leading to a decrease of neurotransmitters release and synaptic efficacy reduction. O-GlcNAcylation and phosphorylation appear to be involved in this synaptic plasticity by finely regulating the activity of specific synaptic proteins. Cortical modulation of O-GlcNAcylation level prevents…
Advisors/Committee Members: Canu, Marie-Hélène (thesis director), Dupont, Erwan (thesis director).
Subjects/Keywords: O-GlcNAcylation; 573.86
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Fourneau, J. (2018). Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation. (Doctoral Dissertation). Université Lille I – Sciences et Technologies. Retrieved from http://www.theses.fr/2018LIL1S105
Chicago Manual of Style (16th Edition):
Fourneau, Julie. “Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation.” 2018. Doctoral Dissertation, Université Lille I – Sciences et Technologies. Accessed January 26, 2021.
http://www.theses.fr/2018LIL1S105.
MLA Handbook (7th Edition):
Fourneau, Julie. “Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation.” 2018. Web. 26 Jan 2021.
Vancouver:
Fourneau J. Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation. [Internet] [Doctoral dissertation]. Université Lille I – Sciences et Technologies; 2018. [cited 2021 Jan 26].
Available from: http://www.theses.fr/2018LIL1S105.
Council of Science Editors:
Fourneau J. Conséquences d’une perturbation de l’expérience sensorimotrice sur la plasticité synaptique du cortex cérébral : implication de deux modifications post-traductionnelles, la phosphorylation et la O-GlcNAcylation : Consequences of sensorimotor perturbation on synaptic plasticity of the cerebral cortex : involvement of two post-translational modifications, phosphorylation and O-GlcNAcylation. [Doctoral Dissertation]. Université Lille I – Sciences et Technologies; 2018. Available from: http://www.theses.fr/2018LIL1S105
23.
Alencar, Sim?ne de Oliveira.
A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM).
Degree: 2018, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/6915
► Esta tese analisa a precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o Agricultura e Ambiente (IEAA), da Universidade Federal do Amazonas (UFAM),…
(more)
▼ Esta tese analisa a precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o Agricultura e Ambiente (IEAA), da Universidade Federal do Amazonas (UFAM), buscando compreender como a precariza??o do trabalho docente se acentua no contexto que ? desenvolvido este programa. A tese que sustentamos foi: A precariza??o do trabalho docente no Brasil vem se evidenciando no processo de expans?o do ensino superior a partir da d?cada de 1995 e se acentua no PARFOR desenvolvido no IEEA da UFAM. Nossa escolha te?rico-metodol?gica sustentou-se no Materialismo Hist?rico-dial?tico, para a compreens?o do objeto e da realidade, o qual traz como categorias inerentes a contradi??o, a totalidade e a media??o. Os dados coletados foram tratados, organizados e analisados a partir da an?lise tem?tica. As categorias de an?lise foram o trabalho como categoria central, a precariza??o, a flexibiliza??o e a intensifica??o. Para o recolhimento dos dados coletamos documentos e entrevistamos 10 (dez) professores do IEAA que trabalharam no PARFOR no per?odo de 2010 a 2015. Com base na pesquisa, verificamos que o trabalho docente ? precarizado desde a sua g?nese, todavia, no PARFOR, h? uma intensifica??o maior da explora??o da for?a de trabalho docente. A aus?ncia do trip? universit?rio (ensino, pesquisa e extens?o), a redu??o do tempo da carga hor?ria, a densidade laboral, s?o fatores que acentuam a precariza??o do trabalho docente.
This thesis analyzes the precariousness of teaching work in PARFOR developed at the Instituto de Educa??o, Agricultura e Ambiente (IEAA), from Universidade Federal do Amazonas (UFAM), seeking to understand how the precariousness of teaching work is emphasized in the context that this program is developed. The thesis we undertook was: The precariousness of teaching work in Brazil has been evidenced in the process of expansion of higher education since the 1995s and is emphasized in PARFOR developed at UFAM/IEEA. Our theoretical-methodological choices were based on historical-dialectical materialism, in order to understand the object and reality, which brings as inherent categories as contradiction, totality and mediation. The collected data were treated, organized and analyzed from the thematic analysis. The categories of analysis were work as a central category, precariousness, flexibilization and intensification. In order to collect the data, we collected documents and interviewed 10 (ten) IEAA/UFAM professors who worked at PARFOR in the period from 2010 to 2015. Based on the research, we verified that the teaching work has been precarious since its genesis, however, in PARFOR there are a greater intensification of the exploitation of the teaching workforce. The absence of the university tripod (teaching, research and extension), the reduction of the time of the workload, the labor density, are factors that accentuate the precariousness of the teaching work.
FAPEAM - Funda??o de Amparo ? Pesquisa do Estado do Amazonas
n?o encontrei dificuldades. Tudo explicado no tutorial e no manual
Advisors/Committee Members: Mour?o, Arminda Rachel Botelho, http://lattes.cnpq.br/3864748731992379, Batista, Eliane Regina Martins, http://lattes.cnpq.br/6865614032821482, Nogueira, Eulina Maria Leite, http://lattes.cnpq.br/7518673342621764, Silva, Paulo Aparecido Dias da, http://lattes.cnpq.br/9966733160906645.
Subjects/Keywords: Precariza??o; Trabalho docente; PARFOR; Expans?o; Itensifica??o; CI?NCIAS HUMANAS: EDUCA??O
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Alencar, S. d. O. (2018). A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM). (Doctoral Dissertation). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/6915
Chicago Manual of Style (16th Edition):
Alencar, Sim?ne de Oliveira. “A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM).” 2018. Doctoral Dissertation, Universidade Federal do Amazonas. Accessed January 26, 2021.
https://tede.ufam.edu.br/handle/tede/6915.
MLA Handbook (7th Edition):
Alencar, Sim?ne de Oliveira. “A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM).” 2018. Web. 26 Jan 2021.
Vancouver:
Alencar SdO. A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM). [Internet] [Doctoral dissertation]. Universidade Federal do Amazonas; 2018. [cited 2021 Jan 26].
Available from: https://tede.ufam.edu.br/handle/tede/6915.
Council of Science Editors:
Alencar SdO. A precariza??o do trabalho docente no PARFOR desenvolvido no Instituto de Educa??o, Agricultura e Ambiente (IEAA) da Universidade Federal do Amazonas (UFAM). [Doctoral Dissertation]. Universidade Federal do Amazonas; 2018. Available from: https://tede.ufam.edu.br/handle/tede/6915

Universidade do Estado do Rio de Janeiro
24.
Girliane Medeiros da Silva.
Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes.
Degree: Master, 2012, Universidade do Estado do Rio de Janeiro
URL: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4061
;
► O presente trabalho tem como propósito refletir sobre a questão da identidade do sujeito de Os cus de Judas, de Lobo Antunes, a partir do…
(more)
▼ O presente trabalho tem como propósito refletir sobre a questão da identidade do sujeito de Os cus de Judas, de Lobo Antunes, a partir do momento em que há um deslocamento espacial do narrador-personagem. Em tempos de guerra colonial, tal deslocamento para o continente africano faz com que o sujeito da narrativa se depare com o outro; isso reflete em sua existência provocando uma crise de identidade a partir da qual ele passa a questionar sua nacionalidade, sua pátria. Ao contestar seu país e suas raízes, o personagem-narrador acaba por macular a identidade portuguesa sustentada tantos séculos por um imaginário que já não mais existe.Obrigado a participar da guerra como combatente, o narrador-personagem observa que aqueles que estão do outro lado, os colonizados, também sofrem com o sistema de governo instituído por Salazar. O processo de alteridade é rasurado e/ou quase desfeito à medida que os laços entre colonizado e colonizador se tornam mais estreitos e se rasuram.Na obra Os cus de Judas, a experiência traumática da guerra instiga o narrador-personagem ao autoexílio, pois o sujeito, ao retornar da guerra na África, torna-se um refugiado dentro de si mesmo e de sua própria nação, ensimesmado e expatriado. Tais considerações colocam em cena os conceitos de identidade do sujeito e da nação revisitados pela memória
El presente trabajo tiene como objetivo reflexionar sobre la cuestión de la identidad en el tema de Los culos de Judas, de Lobo Antunes, desde el momento en que hay un desplazamiento espacial del narrador-personaje. En tiempo de guerra colonial, el desplazamiento para el continente africano hace que el sujeto de la historia cumple con el outro; eso refleja en su existencia provocando una crisis de identidad de la que empieza a cuestionar su nacionalidad, su tierra natal. Al contestar su país y sus raíces, el narrador convierte el significado de la identidad portuguesa, la deshonra , una identidad sostenida a lo largo de siglos, un imaginário que ya no exite más. Con la obligación de participar como combatente de la guerra, el narrador-personaje observa los que están al outro lado, los colonizados, pues también sufren con el sistema de gobierno instituído por Salazar. El proceso de alteridad se desarolla al modo que los vínculos entre el colonizador y el colonizado se vuelven más estrechos. En la obra Los culos de Judas, la experiencia traumática de la guerra le instiga al autoexilio, le convierte en un refugiado en su propia nación, y él se percibe un expatriado cuando regresa a Portugal. Tales consideraciones ponen en juego los conceptos del sujeto y de la nación revisitados por la memória
Advisors/Committee Members: Maria Helena Sansão Fontes, Ângela Beatriz de Carvalho Faria, Claudia Maria de Souza Amorim.
Subjects/Keywords: Guerra colonial; Os cus de Judas; Lobo Antunes; Deslocamento; Identidade; Memória; Fragmentação; Los culos de Judas; Desplazamiento; Identidad; Memoria; Fragmentación; OUTRAS LITERATURAS VERNACULAS; Antunes, Antônio Lobo, 1942-. Os cus de Judas; Identidade (Conceito filosófico) na literatura; Memória na literatura; Análise do discurso narrativo; Portugal Colônias
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Silva, G. M. d. (2012). Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes. (Masters Thesis). Universidade do Estado do Rio de Janeiro. Retrieved from http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4061 ;
Chicago Manual of Style (16th Edition):
Silva, Girliane Medeiros da. “Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes.” 2012. Masters Thesis, Universidade do Estado do Rio de Janeiro. Accessed January 26, 2021.
http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4061 ;.
MLA Handbook (7th Edition):
Silva, Girliane Medeiros da. “Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes.” 2012. Web. 26 Jan 2021.
Vancouver:
Silva GMd. Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes. [Internet] [Masters thesis]. Universidade do Estado do Rio de Janeiro; 2012. [cited 2021 Jan 26].
Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4061 ;.
Council of Science Editors:
Silva GMd. Nos labirintos da memória: o resgate da história e da identidade em Os cus de Judas, de Lobo Antunes. [Masters Thesis]. Universidade do Estado do Rio de Janeiro; 2012. Available from: http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4061 ;
25.
Arrais, Maria do Socorro dos Santos Montoia.
Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada.
Degree: 2019, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/7672
► O mercado educacional no Brasil tem se tornado muito competitivo, conforme o senso da educa??o superior 2019 ? Instituto Nacional de Estudos e Pesquisas Educacionais…
(more)
▼ O mercado educacional no Brasil tem se tornado muito competitivo, conforme o senso da educa??o superior 2019 ? Instituto Nacional de Estudos e Pesquisas Educacionais An?sio Teixeira INEP (dados 2018), 88,20% das Institui??es de Ensino Superior ? IES, s?o particulares. Essas institui??es devidamente credenciadas pelo Minist?rio da Educa??o ? MEC, podem ofertar cursos de Especializa??o Lato Sensu. Conforme a Resolu??o n? 1, de 8 de abril de 2018, as Institui??es de Ensino Superior - IES independem de autoriza??o, reconhecimento e renova??o do reconhecimento (o que lhes garante manter as caracter?sticas de flexibilidade, dinamicidade e agilidade), desde que oferecidos por institui??es credenciadas. Para fazer a diferen?a no mercado, as IES devem oferecer servi?os de qualidade que exige muito investimento tanto intelectual como financeiro. Diante dessa realidade os gestores precisam utilizar as ferramentas de controle para entender melhor o panorama geral entre os custos suas receitas, mas principalmente controlar seus custos, que para esse ramo de neg?cios, s?o muito altos. Os gestores precisam adotar m?todos de gest?o estrat?gica de custos, de forma que tenham condi??es de saber como sua empresa est? diante de sua pr?pria realidade, fazer compara??es com outras empresas do mesmo setor, bem como ter subs?dios suficientes para a tomada de decis?es. Este trabalho, atrav?s de uma pesquisa da an?lise de dados em uma Institui??o de Ensino Superior privadas que oferecem cursos de Especializa??o na modalidade Lato Sensu, situada na cidade de Porto Velho, busca, atrav?s de uma metodologia apropriada, demonstrar a import?ncia da aplica??o de m?todos adequados de gest?o de custos.
The educational market in Brazil has become very competitive, according to the sense of higher education 2019 - National Institute of Educational Studies and Research An?sio Teixeira INEP (data 2018), 88.20% of Higher Education Institutions - IES, are private. These institutions, duly accredited by the Ministry of Education - MEC, can offer Lato Sensu Specialization courses. According to Resolution No. 1, of April 8, 2018, Higher Education Institutions (HEIs) are independent of authorization, recognition and renewal of recognition (which guarantees them to maintain the characteristics of flexibility, dynamism and agility), as long as offered by accredited institutions. To make a difference in the market, HEIs must offer quality services that require a lot of investment, both intellectual and financial. Given this reality, managers need to use the control tools to better understand the general picture between their revenue costs, but mainly to control their costs, which for this line of business are very high. Managers need to adopt strategic cost management methods, so that they are able to know how their company is facing their own reality, make comparisons with other companies in the same sector, as well as have sufficient subsidies for decision making. This work, through a research of data analysis in a private Higher Education Institution that…
Advisors/Committee Members: Oliveira, Marcelo Albuquerque de, http://lattes.cnpq.br/3181349086683086, Reis, D?rcio Luiz, http://lattes.cnpq.br/0744595360592397, Medeiros, Hyggor da Silva, http://lattes.cnpq.br/0036449305312107.
Subjects/Keywords: Educa??o - Aspectos econ?micos; Educa??o - Custos; Pesquisa educacional; Gest?o escolar; Ensino Superior no Brasil; GEST?O DA PRODU??O; Custo; Educa??o; Gest?o; Resultado
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Arrais, M. d. S. d. S. M. (2019). Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/7672
Chicago Manual of Style (16th Edition):
Arrais, Maria do Socorro dos Santos Montoia. “Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada.” 2019. Masters Thesis, Universidade Federal do Amazonas. Accessed January 26, 2021.
https://tede.ufam.edu.br/handle/tede/7672.
MLA Handbook (7th Edition):
Arrais, Maria do Socorro dos Santos Montoia. “Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada.” 2019. Web. 26 Jan 2021.
Vancouver:
Arrais MdSdSM. Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2019. [cited 2021 Jan 26].
Available from: https://tede.ufam.edu.br/handle/tede/7672.
Council of Science Editors:
Arrais MdSdSM. Gest?o de custos nos servi?os educacionais: modelo de controle estrat?gico de custos nos cursos de especializa??o em uma institui??o de ensino superior privada. [Masters Thesis]. Universidade Federal do Amazonas; 2019. Available from: https://tede.ufam.edu.br/handle/tede/7672
26.
Costa, Tereza Raquel Negreiros do Nascimento; http://lattes.cnpq.br/8130378775526282.
O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas.
Degree: 2020, Universidade Federal do Amazonas
URL: https://tede.ufam.edu.br/handle/tede/8065
► A forma??o profissional em Servi?o Social tem objetivo de proporcionar a constru??o de perfis profissionais alinhados com o projeto profissional que se direciona, de modo…
(more)
▼ A forma??o profissional em Servi?o Social tem objetivo de proporcionar a constru??o de perfis profissionais alinhados com o projeto profissional que se direciona, de modo geral, ? compreens?o e interven??o cr?tica diante das express?es da quest?o social da sociedade capitalista, portanto, ? necess?ria avalia??o da forma??o e observa??o dos meios adotados para sua avalia??o a fim de que seja observada se h? coer?ncia e real contribui??o ao processo formativo. Assim, a pesquisa teve como objetivo geral: analisar a avalia??o da forma??o profissional em Servi?o Social por meio do Exame Nacional de Desempenho de Estudantes (ENADE), com ?nfase ? aprecia??o dada aos cursos existentes no Estado do Amazonas nas v?rias edi??es deste instrumento avaliativo, com o intuito de contribuir para o aprimoramento do processo avaliativo. Para isto, os objetivos espec?ficos foram problematizar a ado??o do ENADE como meio de avalia??o da forma??o em Servi?o Social; avaliar os conte?dos das provas do ENADE com base nos n?cleos de fundamenta??o da forma??o profissional em Servi?o Social; e identificar a avalia??o dada ? forma??o profissional em Servi?o Social no Amazonas a partir da ?tica do ENADE. Foram desenvolvidas pesquisa bibliogr?fica e documental, sob abordagem do enfoque misto (que engloba tanto os aspectos quantitativos quanto os qualitativos do objeto), de natureza explicativa, sob direcionamento do m?todo cr?tico-dial?tico. Os materiais primordiais ? an?lise foram as provas do ENADE, as legisla??es que regulamentam o exame e as diretrizes curriculares da forma??o em Servi?o Social, como tamb?m os relat?rios de ?rea e de cada institui??o que oferece o curso de Servi?o Social do Amazonas, possibilitando que, por meio destes ?ltimos documentos, visualiz?ssemos o dom?nio dos estudantes sobre os conte?dos da forma??o a partir dos acertos e erros nas provas, e o conhecimento do perfil dos estudantes participantes do exame. Para capta??o dos dados a partir documentos, foram adotadas as t?cnicas de an?lise documental e an?lise de conte?do que possibilitaram o conhecimento da estrutura e organiza??o deles, bem como das intencionalidades entranhadas. Diante disto, foi identificado que o ENADE ? insuficiente para avaliar a forma??o profissional, aqui em quest?o a forma??o em Servi?o Social, representando reducionismo ao ser conduzido sem articula??o com as demais propostas trazidas pelo SINAES (avalia??o interna e externa, com visita in loco, alcan?ando discentes, docentes e t?cnicos-administrativos, dentre outras), mas, por outro lado, no que tange ? sua fun??o de exame de desempenho, possibilita aproxima??o sobre os conhecimentos obtidos pelos discentes durante a gradua??o.
Professional training in Social Work aims to provide the construction of professional profiles aligned with the professional project that is directed, in general, to understanding and critical intervention in the face of the expressions of the social issue of capitalist society, therefore, it is necessary to evaluate the training and observation of the means adopted…
Advisors/Committee Members: Andrade, Roberta Ferreira Coelho de, http://lattes.cnpq.br/6518749034599659, Prates, Jane Cruz, http://lattes.cnpq.br/1901733198724508, Pinheiro, Hamida Assun??o, http://lattes.cnpq.br/6392995719018586.
Subjects/Keywords: Estudantes de servi?o social; Servi?o social - Orienta??o profissional; CIENCIAS SOCIAIS APLICADAS; Forma??o Profissional; Servi?o Social; ENADE; Avalia??o da Forma??o
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Costa, T. R. N. d. N. h. c. b. (2020). O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from https://tede.ufam.edu.br/handle/tede/8065
Chicago Manual of Style (16th Edition):
Costa, Tereza Raquel Negreiros do Nascimento; http://lattes cnpq br/8130378775526282. “O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas.” 2020. Masters Thesis, Universidade Federal do Amazonas. Accessed January 26, 2021.
https://tede.ufam.edu.br/handle/tede/8065.
MLA Handbook (7th Edition):
Costa, Tereza Raquel Negreiros do Nascimento; http://lattes cnpq br/8130378775526282. “O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas.” 2020. Web. 26 Jan 2021.
Vancouver:
Costa TRNdNhcb. O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2020. [cited 2021 Jan 26].
Available from: https://tede.ufam.edu.br/handle/tede/8065.
Council of Science Editors:
Costa TRNdNhcb. O ENADE constr?i pontes ou edifica muros? Uma leitura da forma??o profissional em Servi?o Social no Amazonas. [Masters Thesis]. Universidade Federal do Amazonas; 2020. Available from: https://tede.ufam.edu.br/handle/tede/8065
27.
Mônica Ribeiro Falcão.
As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem.
Degree: 2007, Universidade Católica de Santos
URL: http://biblioteca.unisantos.br/tede/tde_busca/arquivo.php?codArquivo=218
► O presente trabalho enfoca o papel do professor no processo ensino-aprendizagem. Sendo assim, buscamos, nas relações pedagógicas desenvolvidas num contexto escolar, retratar a ação docente…
(more)
▼ O presente trabalho enfoca
o papel do professor no processo ensino-aprendizagem. Sendo assim, buscamos, nas relações pedagógicas desenvolvidas num contexto escolar, retratar a açã
o docente para compreender
o que tem se concretizado em sala de aula através da prática dos professores.
O problema da pesquisa se constitui através da questã
o: de que maneira
o professor, como mediador do conhecimento no processo educativo, tem se utilizado de práticas pedagógicas que conduzam os alunos a uma aprendizagem mais significativa? Para tanto, estabelece como objetivo principal compreender como professores e alunos conduzem as relações entre ensinar e aprender, cotidianamente, e de que modo
o professor exerce
o seu papel de mediador do conhecimento nessas relações.
O objeto de estudo sã
o as relações entre ensinar e aprender e seu foco é a atividade docente que intervém e envolve
o aluno no processo pedagógico, verificando em que medida as práticas dos professores estã
o voltadas para a aquisiçã
o de uma aprendizagem mais significativa. À luz do referencial teórico de Vygotsky (1987, 1998), Cunha (1989), Libâneo (1994, 2001, 2004), Sacristan e Pérez Gómez (1998), Charlot (2000, 2005), Fontana (2000), Abdalla (2002, 2006), Gadotti (2003), Tardif e Lessard (2005), e Rios (2006) que analisam as relações de ensino e aprendizagem,
o trabalho docente, a prática pedagógica e as relações interpessoais em sala de aula. A pesquisa de cunho qualitativo
utiliza, para a coleta de registros e abordagem do objeto,
o estudo de caso. Como fonte dessa coleta,
utiliza-se de entrevistas semi-estruturadas com seis professores e dez alunos, a observaçã
o do cotidiano escolar e a produçã
o textual dos estudantes. Como forma de registro das observações, recorre ao diário de campo. A organizaçã
o dos dados proporcionou a elaboraçã
o de três quadros de categorias de análise: Mediaçã
o Pedagógica, a categoria principal, que estruturou as seguintes:
o Sentido do Ensinar e
o Sentido do Aprender. Este estudo buscou apresentar alguns conceitos teóricos, no sentido de colaborar para a compreensã
o do papel do professor no processo ensino-aprendizagem. Os resultados demonstram que professores e alunos, apesar das adversidades, têm procurado caminhos para a construçã
o do conhecimento em sala de aula. Os professores têm superado a deficiência dos cursos de formaçã
o, que nã
o os preparam para a realidade escolar, e elaboram estratégias particulares de atuaçã
o. Embora, muitas vezes, as maneiras de interaçã
o estabelecidas em sala de aula nã
o sejam ideais e as relações entre professores e alunos e, conseqüentemente, entre ensinar e aprender dependam da intervençã
o desse professor para que os caminhos para uma aprendizagem mais significativa sejam fortalecidos.
Advisors/Committee Members: Maria de Fátima Barbosa Abdalla.
Subjects/Keywords: relações entre o ensinar e o aprender; o papel do professor; mediação pedagógica.; EDUCACAO
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Falcão, M. R. (2007). As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem. (Thesis). Universidade Católica de Santos. Retrieved from http://biblioteca.unisantos.br/tede/tde_busca/arquivo.php?codArquivo=218
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Falcão, Mônica Ribeiro. “As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem.” 2007. Thesis, Universidade Católica de Santos. Accessed January 26, 2021.
http://biblioteca.unisantos.br/tede/tde_busca/arquivo.php?codArquivo=218.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Falcão, Mônica Ribeiro. “As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem.” 2007. Web. 26 Jan 2021.
Vancouver:
Falcão MR. As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem. [Internet] [Thesis]. Universidade Católica de Santos; 2007. [cited 2021 Jan 26].
Available from: http://biblioteca.unisantos.br/tede/tde_busca/arquivo.php?codArquivo=218.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Falcão MR. As relações entre o ensinar e o aprender : o professor como mediador no processo ensino-aprendizagem. [Thesis]. Universidade Católica de Santos; 2007. Available from: http://biblioteca.unisantos.br/tede/tde_busca/arquivo.php?codArquivo=218
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
28.
MICHELLE ORANE SCHEMBERGER.
CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES).
Degree: 2009, UNIVERSIDADE ESTADUAL DE PONTA GROSSA
URL: http://www.bicen-tede.uepg.br/tde_busca/arquivo.php?codArquivo=469
► Neste estudo, a fra??o heterocrom?tica do cromossomo W de Apareiodon sp. foi isolado por microdissec??o com posterior amplifica??o por DOP-PCR. As seq??ncias obtidas foram utilizadas…
(more)
▼ Neste estudo, a fra??o heterocrom?tica do cromossomo W de Apareiodon sp. foi isolado por microdissec??o com posterior amplifica??o por DOP-PCR. As seq??ncias obtidas foram utilizadas no procedimento de hibrida??o in situ fluorescente em cromossomos de esp?cies de Parodontidae. Esta sonda foi denominada WAp. Assim, de posse deste marcador e de outros j? dispon?veis o trabalho apresentou uma an?lise de citogen?tica molecular em exemplares da fam?lia presentes em diferentes bacias hidrogr?ficas brasileiras. Foram analisadas as esp?cies: Apareiodon sp., A. ibitiensis, A. vladii, A. piracicabae, A. vittatus, A. affinis, P. hilarii, P. moreirai, P. nasus e P. pongoensis. Os resultados evidenciaram a proximidade da localiza??o do marcador do rDNA 18S encontrado em esp?cies de Parodon em compara??o ao grupo irm?o Anostomidae. Ainda, foi visualizado um alta identidade do par cromoss?mico portador dos s?tios de rDNA 5S em todos Parodontidae estudados. Com o mapeamento dos DNAs repetitivos WAp e pPh2004 por hibrida??o in situ fluorescente nos cromossomos de algumas esp?cies de Parodontidae foram lan?adas hip?teses de origem e diferencia??o do sistema de cromossomos sexuais ZZ/ZW a partir de uma invers?o alocando s?tios WAp em regi?o proximal de um par cromoss?mico metac?ntrico. Esses resultados permitiram inferir tamb?m que o sistema de cromossomos sexuais m?ltiplos ZZ/ZW1W2 de A. affinis pode ter origem de um sistema ZW similar ao encontrado em popula??es ancestrais da esp?cie P. hilarii. Assim, este trabalho contribui para o entendimento da evolu??o e diversifica??o do genoma de algumas esp?cies de Parodontidae, principalmente para o esclarecimento da origem e diferencia??o dos cromossomos sexuais.
In this study, the fraction of the heterochromatin of the Apareiodon sp. chromosome W was isolated by microdissection with subsequent amplification by DOP-PCR. The sequences obtained were used in the procedure of the fluorescence in situ hybridization in Parodontidae species chromosomes. This probe was named WAp. Then, with this marker and others available, the study presented a molecular cytogenetic analysis in Parodontidae species present in different Brazilian hydrographic basin. The species analyzed were: Apareiodon sp., A. ibitiensis, A. vladii, A. piracicabae, A. vittatus, A. affinis, P. hilarii, P. moreirai, P. nasus and P. pongoensis. The results reveal closeness of the location of 18S rDNA marker found in Parodon species compared to the sister group Anostomidae. Still, it has been viewed a high identity chromosome pair bearing the rDNA 5S sites in all Parodontidae studied. Mapping of repetitive DNAs WAp and pPh2004 by fluorescence in situ hybridization in chromosomes of some species of Parodontidae permitted deduce the origin and differentiation of sex chromosome system ZZ/ZW from a inversion allocating proximal region WAp sites of a chromosome metacentric pair. These results allowed inferring that the sex chromosome system multiple ZZ/ZW1W2 of A. affinis can originate from one system ZW similar to that found in ancient…
Advisors/Committee Members: Marcelo Ricardo Vicari, Marta Margarete Cestari, Rafael Bueno Noleto, Mara Cristina de Almeida.
Subjects/Keywords: Parodontidae; Dispers?o de sitio rDNA; evolu??o cariotipica; microdissec??o do cromossomoW; BIOLOGIA MOLECULAR
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
SCHEMBERGER, M. O. (2009). CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES). (Thesis). UNIVERSIDADE ESTADUAL DE PONTA GROSSA. Retrieved from http://www.bicen-tede.uepg.br/tde_busca/arquivo.php?codArquivo=469
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
SCHEMBERGER, MICHELLE ORANE. “CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES).” 2009. Thesis, UNIVERSIDADE ESTADUAL DE PONTA GROSSA. Accessed January 26, 2021.
http://www.bicen-tede.uepg.br/tde_busca/arquivo.php?codArquivo=469.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
SCHEMBERGER, MICHELLE ORANE. “CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES).” 2009. Web. 26 Jan 2021.
Vancouver:
SCHEMBERGER MO. CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES). [Internet] [Thesis]. UNIVERSIDADE ESTADUAL DE PONTA GROSSA; 2009. [cited 2021 Jan 26].
Available from: http://www.bicen-tede.uepg.br/tde_busca/arquivo.php?codArquivo=469.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
SCHEMBERGER MO. CITOGEN?TICA MOLECULAR EM ESP?CIES DA FAM?LIA PARODONTIDAE (PISCES; CHARACIFORMES). [Thesis]. UNIVERSIDADE ESTADUAL DE PONTA GROSSA; 2009. Available from: http://www.bicen-tede.uepg.br/tde_busca/arquivo.php?codArquivo=469
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Penn State University
29.
Kim, Seong Jo.
PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O.
Degree: 2011, Penn State University
URL: https://submit-etda.libraries.psu.edu/catalog/12561
► Efficient execution of large-scale scientific applications requires high-performance computing systems designed to meet the I/O requirements. Most I/O- and data-intensive parallel applications access multiple layers…
(more)
▼ Efficient execution of large-scale scientific applications requires high-performance
computing systems designed to meet the I/
O requirements. Most I/
O- and data-intensive
parallel applications access multiple layers in the I/
O stack during the operations. Typ-
ical I/
O requests from these applications may include accesses to high-level I/
O libraries
such as Parallel netCDF and HDF5, the MPI I/
O library, and parallel file systems such
as PVFS, in turn supported by native file systems in Linux. To design and implement
parallel applications that exercise this I/
O stack, one must understand the flow and in-
teraction of I/
O calls through the entire I/
O stack. Such understanding helps identify
I/
O bottlenecks and thus exploit the potential performance in different layers of the
storage hierarchy. To trace the execution of I/
O calls and to understand the complex
interactions among multiple user libraries and file systems, we implement a GUI-based
integrated profiling and analysis environment, PAVIS. Our implementation automati-
cally generates an instrumented I/
O stack, runs applications, and visualizes detailed
statistics in terms of user-specified metrics of interest.
Advisors/Committee Members: Mahmut Taylan Kandemir, Thesis Advisor/Co-Advisor, Mahmut Taylan Kandemir, Thesis Advisor/Co-Advisor, Chitaranjan Das, Thesis Advisor/Co-Advisor.
Subjects/Keywords: MPI-IO; PVFS; collective I/O; I/O stack; code instrumentation; Parallel I/O visualization
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Kim, S. J. (2011). PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O. (Thesis). Penn State University. Retrieved from https://submit-etda.libraries.psu.edu/catalog/12561
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Kim, Seong Jo. “PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O.” 2011. Thesis, Penn State University. Accessed January 26, 2021.
https://submit-etda.libraries.psu.edu/catalog/12561.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Kim, Seong Jo. “PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O.” 2011. Web. 26 Jan 2021.
Vancouver:
Kim SJ. PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O. [Internet] [Thesis]. Penn State University; 2011. [cited 2021 Jan 26].
Available from: https://submit-etda.libraries.psu.edu/catalog/12561.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Kim SJ. PERFORMANCE ANALYSIS AND VISUALIZATION FOR HIGH PERFORMANCE PARALLEL I/O. [Thesis]. Penn State University; 2011. Available from: https://submit-etda.libraries.psu.edu/catalog/12561
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
30.
Oliveira, Ana Cec?lia Marques de.
A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011.
Degree: 2014, Universidade Federal do Amazonas
URL: http://tede.ufam.edu.br/handle/tede/4094
► Em raz?o da crescente globaliza??o da economia, com as disputas por mercados a n?vel mundial, s?o evidentes as mudan?as socioecon?micas, pol?ticas, culturais, jur?dicas e tecnol?gicas…
(more)
▼ Em raz?o da crescente globaliza??o da economia, com as disputas por mercados a n?vel mundial, s?o evidentes as mudan?as socioecon?micas, pol?ticas, culturais, jur?dicas e tecnol?gicas no chamado mundo do trabalho. Em meio a essas mudan?as uma importante quest?o emerge no conjunto de transforma??es que est?o reconfigurando o mundo do trabalho, ? a da qualifica??o do trabalhador. Que novas demandas s?o postas ao trabalhador para atuar neste cen?rio? Pensar os desafios da qualifica??o no e para o trabalho nos insere em um ?ngulo que interliga os complexos processos de transforma??o no mundo do trabalho, as pol?ticas voltadas para lidar com os subprodutos, especialmente o desemprego, as a??es das diversas institui??es educacionais e de forma??o do trabalhador. A quest?o sobre a forma??o do homem em sua totalidade, perante o modo de produ??o capitalista, ? central para a compreens?o das rela??es sociais e sua poss?vel transforma??o. A import?ncia da rela??o trabalho-educa??o se justifica porque justamente a partir dela a forma??o humana configura-se como processo contradit?rio e marcado pelos valores capitalistas. Esse processo, ? medida que se institucionaliza, cria categorias apropriadas para defini-lo socialmente, como, por exemplo: educa??o, trabalho e qualifica??o profissional. A relev?ncia dessa tem?tica nos imp?e o desafio de desvelar as concep??es e as a??es que, velada ou explicitamente, contemplam as pol?ticas p?blicas de qualifica??o profissional no e para o Estado do Amazonas. Vislumbramos o Centro de Educa??o Tecnol?gica do Amazonas ? CETAM - enquanto pol?tica p?blica de educa??o profissional - como poss?vel cen?rio para a investiga??o de como o poder p?blico amazonense trata a qualifica??o profissional do trabalhador mediante os imperativos do mercado de trabalho e os desafios amaz?nicos. Faz-se necess?rio fazer um levantamento dos programas ofertados e de como ? composta a estrutura organizacional do CETAM, investigando as a??es, perspectivas de sociedade, as concep??es de rela??o entre trabalho, educa??o e sociedade que norteiam este enfoque.
Due to the increasing globalization of the economy, with disputes for markets in a global level, the socioeconomic, political, cultural, legal and technological changes are blatant in the world of work. Amidst these changes an important issue emerges from the set of transformations which are reconfiguring the world of work, it is the qualification of the worker. Which new demands are posed to the worker in this scenario? Thinking about the challenges of qualification in and for the work places us in an angle which connects the complex transformation processes in the world of work, the policies to deal with byproducts, especially unemployment, the actions from various educational institutions and the training of the worker. The issue about the shaping of the man in his totallity, before the capitalist mode of production, is central to the understanding of the social relations and its possible transformation. The importance of the work-education relation is justified…
Advisors/Committee Members: Mour?o, Arminda Rachel Botelho, Oliveira, Selma Suely Ba?al de, http://lattes.cnpq.br/5050471052673175, Pinheiro, Maria das Gra?as S? Peixoto, Santos, ?gida Maria Cavalcante dos.
Subjects/Keywords: Educa??o; Trabalho; Educa??o Profissional; education; work; Professional Education; CI?NCIAS HUMANAS: EDUCA??O
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Oliveira, A. C. M. d. (2014). A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011. (Masters Thesis). Universidade Federal do Amazonas. Retrieved from http://tede.ufam.edu.br/handle/tede/4094
Chicago Manual of Style (16th Edition):
Oliveira, Ana Cec?lia Marques de. “A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011.” 2014. Masters Thesis, Universidade Federal do Amazonas. Accessed January 26, 2021.
http://tede.ufam.edu.br/handle/tede/4094.
MLA Handbook (7th Edition):
Oliveira, Ana Cec?lia Marques de. “A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011.” 2014. Web. 26 Jan 2021.
Vancouver:
Oliveira ACMd. A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011. [Internet] [Masters thesis]. Universidade Federal do Amazonas; 2014. [cited 2021 Jan 26].
Available from: http://tede.ufam.edu.br/handle/tede/4094.
Council of Science Editors:
Oliveira ACMd. A implanta??o dos programas de qualifica??o profissional Centro de Educa??o Tecnol?gica do Amazonas ? CETAM ? 2003 a 2011. [Masters Thesis]. Universidade Federal do Amazonas; 2014. Available from: http://tede.ufam.edu.br/handle/tede/4094
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