publisher:("University of Michigan")

University of Michigan

1. Zehnpfennig, John D., II. Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere.

Degree: 2011, University of Michigan

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=1496248

► Here we provide the theoretical background, calculate expected results, and experimentally show optically-induced Surface Acoustic Waves (SAW) of three distinct families of material deformation… (more)

Subjects/Keywords: Engineering, Electronics and Electrical; Physics, Optics; Engineering, Materials Science

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APA (6^th Edition):

Zehnpfennig, John D., I. (2011). Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere. (Thesis). University of Michigan. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=1496248

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zehnpfennig, John D., II. “Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere.” 2011. Thesis, University of Michigan. Accessed April 20, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=1496248.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zehnpfennig, John D., II. “Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere.” 2011. Web. 20 Apr 2021.

Vancouver:

Zehnpfennig, John D. I. Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere. [Internet] [Thesis]. University of Michigan; 2011. [cited 2021 Apr 20]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=1496248.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zehnpfennig, John D. I. Surface Optomechanics| Forward and Backward Scattered Surface Acoustic Waves in Silica Microsphere. [Thesis]. University of Michigan; 2011. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=1496248

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Martens, Jennifer. Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department.

Degree: 2018, University of Michigan-Flint

URL: http://pqdtopen.proquest.com/#viewpdf?dispub=10680642

► The purpose of this exploratory qualitative study was to identify experiences or barriers that arise during the first year as Certified Registered Nurse Anesthetists… (more)

▼ The purpose of this exploratory qualitative study was to identify experiences or barriers that arise during the first year as Certified Registered Nurse Anesthetists (CRNAs) transition into management and; if these shared experiences can prepare future CRNA managers by providing insight into what knowledge, skills, and abilities are necessary to ensure a smooth and successful career transition. A representative sample by email and Facebook (FB) elicited 18 phone interviews of current and past Certified Registered Nurse Anesthetist (CRNA) managers. One interviewer asked 16 questions: seven demographic and nine open-ended. Survey information was (1) transcribed, (2) reviewed and de-identified, and (3) coded for content and classical analysis by two experienced independent coders. A coding tree was developed by coders after independent and random assessment of codes with an IRR (0.93). NVivo 11 software was used to assist with analysis of codes. CRNA participants (66%) had less than five years of CRNA management experience, and 61% had no previous management experience or education before accepting their first role as a CRNA manager. An incidental finding, 83% of participants were reluctant managers and 76% of CRNA managers devoted greater than 50% of their time to performing clinical duties over managerial duties. Two resources that CRNA participants agreed were helpful resources during transition included: mentors (83%) and previous education or experiences (44%), especially in business, finance, or management. The skills CRNA participants believed were important during transition included people skills (56%), financial knowledge (33%), and communication (28%). CRNA managers are more likely to be reluctant managers that may be relatively new in the role, and with no previous management experience or education. Recommendations for new CRNA managers during transition included; mastering “people skills,” either through relationship management or communication skills. Derailment may be avoided if new managers consider the results of this investigation.

Subjects/Keywords: Management; Nursing; Health care management

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APA (6^th Edition):

Martens, J. (2018). Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department. (Thesis). University of Michigan-Flint. Retrieved from http://pqdtopen.proquest.com/#viewpdf?dispub=10680642

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Martens, Jennifer. “Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department.” 2018. Thesis, University of Michigan-Flint. Accessed April 20, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=10680642.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Martens, Jennifer. “Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department.” 2018. Web. 20 Apr 2021.

Vancouver:

Martens J. Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department. [Internet] [Thesis]. University of Michigan-Flint; 2018. [cited 2021 Apr 20]. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10680642.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Martens J. Certified Registered Nurse Anesthetists' Transition to Manager of an Anesthesia Department. [Thesis]. University of Michigan-Flint; 2018. Available from: http://pqdtopen.proquest.com/#viewpdf?dispub=10680642

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Borovika, Alina. Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions.

Degree: PhD, Chemistry, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113511

► Oxocarbenium ions are common intermedates or transition states for a variety of biological and synthetic transformations. Due to the fact that oxocarbenium ions are typically… (more)

▼ Oxocarbenium ions are common intermedates or transition states for a variety of biological and synthetic transformations. Due to the fact that oxocarbenium ions are typically much more reactive than iminium ions, their reactivity is difficult to control. Especially challenging reactions of oxocarbeniums are stereoselective transformations. While there are several approaches to perform reactions of oxocarbeniums asymetrically, the Nagorny group is particularly interested in using chiral hydrogen bond donors and Brønsted acids as catalysts for these reactions. Chapter 1 of this thesis provides an introduction to chemistry of oxocarbenium ions, their generation and use in asymmetric reactions. Both anion activation and protonation of acetals and vinyl ethers with chiral hydrogen bond donors and chiral Brønsted acids are covered in this chapter. Chapter 2 discusses ionic Diels-Alder reaction as well as the use of thiophosphoramide as a co-catalysts for promoting this transformation. Thiophosphoramide catalyst was found to bind sulfonate anions and was used to separate the vinyl oxocarbenium/sulfonate ion pair. This effect leads to acceleration of the Diels-Alder reaction of unsaturated acetals. Thiophosphoramides are the most effective cocatalysts because of the stronger counterion activation effect resulting from three, rather than two, hydrogen bonds involved in anion binding. Chapter 3 of this manuscript describes development of the first chiral catalyst-controlled enantioselective ionic Diels-Alder reaction of unsaturated acetals. Chiral BINOL-based N-triflylphosphoramides were used as catalysts for this transformation. Moderate enantioselectivities (up to 80:20 e.r.) have been obtained when α,β-unsaturated dioxolanes were employed as the dienophiles. These reactions demonstrate strong dependence on the counterion coordinating properties and solvent polarity, a behavior characteristic of oxocarbenium ions. Finally, Chapter 4 describes attempts of stereo- and regioselective aminoglycosides via desymmetrization of meso-2-deoxystreptamine using chiral phosphoric acids as catalysts. We showed that chiral phosphoric acids facilitate desymmetrization of meso-diols via glycosylation reactions using mannose-α-trichloroacetimidate. Chiral phosphoric acid-promoted mannosylation of 2-deoxystreptamine produces a mixture of two α-mannosides with up to 1:5 (O-4 : O-6) regioselectivity. This is the first report of desymmetrization of meso-diols via glycosylation using chiral phosphoric acids as catalysts. This method has a potential to be applied for glycodiversification of 2-deoxystreptamine and synthesis of new aminoglycoside antibiotics. Advisors/Committee Members: Nagorny, Pavel (committee member), Grembecka, Jolanta E. (committee member), Montgomery, John (committee member), Sanford, Melanie (committee member).

Subjects/Keywords: chiral Bronsted acids; hydrogen bond donors; oxocarbenium ions; [4+2] cycloaddition; glycosylation; 2-deoxystreptamine; Chemistry; Science

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APA (6^th Edition):

Borovika, A. (2015). Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113511

Chicago Manual of Style (16^th Edition):

Borovika, Alina. “Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113511.

MLA Handbook (7^th Edition):

Borovika, Alina. “Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions.” 2015. Web. 20 Apr 2021.

Vancouver:

Borovika A. Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113511.

Council of Science Editors:

Borovika A. Advances in Bronsted Acid Catalysis: Reactions of Oxocarbenium Ions. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113511

4. Peczalski, Adam. Piezoelectric Fused Silica Resonators for Timing References.

Degree: PhD, Electrical Engineering, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/135878

► MEMS resonators have the capability to match or exceed the performance of state-of-the-art quartz timing references at a fraction of the size, power, and cost.… (more)

▼ MEMS resonators have the capability to match or exceed the performance of state-of-the-art quartz timing references at a fraction of the size, power, and cost. To enable this capability, this work investigates the use of fused silica as a substrate for piezoelectrically actuated resonators for applications in timing references. This thesis presents the design and fabrication of a piezoelectrically actuated fused silica resonator. The fabricated resonators show a quality factor (Q) of 19,671 at 4.96 MHz with an insertion loss of 16.9 dB, and is the first reported example of a piezoelectrically actuated fused silica resonator in literature. An in-depth investigation into loss mechanisms in fused silica is performed in order to identify and address the major losses in the device and maximize potential performance. Multiple experimental and analytical investigations are presented, with a new form of loss, known as charge redistribution, presented as a possible dominant loss in these piezoelectric resonators. This loss mechanism is analytically modeled and simulated to have a Q of 25,100, within 20% of the experimentally measured devices. The temperature sensitivity of fused silica is also addressed; as fused silica shows a temperature coefficient of elasticity almost three times higher than that shown in uncompensated silicon. Both active and passive methods of temperature compensation are implemented, including a fused silica ovenized platform and nickel-refilled trenches for temperature compensation. The nickel-refilled trenches are shown to reduce temperature sensitivity in piezoelectrically actuated fused silica resonators from 78 ppm/K to 50 ppm/K, with larger compensation possible but complete compensation infeasible from passive techniques alone. From this, a dual-mode system is proposed for use in ovenized systems where two modes are simultaneously activated in a single device volume. In this system, one mode acts as a stable reference frequency and the second mode acts as a temperature sensor, allowing for extremely accurate ovenization. A silicon-based prototype is developed, showing a +14 ppm/K temperature difference between the two modes, with additional temperature differential possible through the addition of material-based passive compensation. Advisors/Committee Members: Raieszadeh, Mina (committee member), Grosh, Karl (committee member), Gianchandani, Yogesh B (committee member), Najafi, Khalil (committee member).

Subjects/Keywords: MEMS; Resonator; Fused Silica; Piezoelectric Actuation; Timing References; Charge Redistribution; Electrical Engineering; Engineering

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APA (6^th Edition):

Peczalski, A. (2016). Piezoelectric Fused Silica Resonators for Timing References. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/135878

Chicago Manual of Style (16^th Edition):

Peczalski, Adam. “Piezoelectric Fused Silica Resonators for Timing References.” 2016. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/135878.

MLA Handbook (7^th Edition):

Peczalski, Adam. “Piezoelectric Fused Silica Resonators for Timing References.” 2016. Web. 20 Apr 2021.

Vancouver:

Peczalski A. Piezoelectric Fused Silica Resonators for Timing References. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/135878.

Council of Science Editors:

Peczalski A. Piezoelectric Fused Silica Resonators for Timing References. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/135878

University of Michigan

5. Lipsius, Benjamin. Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics.

Degree: PhD, Economics, 2019, University of Michigan

URL: http://hdl.handle.net/2027.42/153467

► This dissertation is comprised of three essays. The first and third chapter explore possible causes of the falling U.S. labor share. They show, first, that… (more)

▼ This dissertation is comprised of three essays. The first and third chapter explore possible causes of the falling U.S. labor share. They show, first, that labor-market concentration is an implausible driver of the falling labor share and, second, that within-industry wages are not keeping up with output. The second chapter ins concerned with private equity and the financialization of the U.S. economy. Using U.S. administrative data, Chapter 1 shows that the employment-weighted average labor market concentration has been declining since 1980 – the opposite of the change needed to explain the falling labor share. The relationship between wages and labor market concentration has also weakened (become less negative) over that time. Together, these results make labor market concentration an implausible driver of the falling labor share despite a strong, negative relationship between labor market concentration and wages. Chapter 2, work with Steven J. Davis, John Haltiwanger, Kyle Handley, Josh Lerner, and Javier Miranda, studies the impact of U.S. private equity buyouts on firm-level employment, job reallocation, wages, and labor productivity. Our sample covers thousands of buyouts from 1980 to 2013, which we link to Census micro data on the target firms, their establishments, and millions of comparable firms and establishments that serve as controls. Our results uncover striking differences in the real effects of buyouts, depending on the nature of the target firm, GDP growth, and credit market conditions. Employment at target firms shrinks by nearly 13% relative to controls over two years in buyouts of publicly listed firms but expands by 11% in buyouts of privately held firms. Slower GDP growth after the buyout brings lower employment growth at targets (relative to controls), as does a widening of credit spreads. Buyouts lead to productivity gains at target firms relative to controls – nine percentage points, on average, over two years post buyout. Tighter credit conditions at the time of the buyout are associated with much larger post-buyout productivity gains in target firms. A post-buyout widening of credit spreads or slowdown in GDP growth sharply curtails or reverses productivity gains in public-to-private deals. Chapter 3 documents that the falling labor share comes entirely from decreases of within-sector labor shares… Advisors/Committee Members: Shapiro, Matthew D (committee member), Schmalz, Martin C (committee member), Brown, Charles C (committee member), Handley, Kyle (committee member).

Subjects/Keywords: Macroeconomics; Economics; Business and Economics

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APA (6^th Edition):

Lipsius, B. (2019). Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/153467

Chicago Manual of Style (16^th Edition):

Lipsius, Benjamin. “Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics.” 2019. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/153467.

MLA Handbook (7^th Edition):

Lipsius, Benjamin. “Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics.” 2019. Web. 20 Apr 2021.

Vancouver:

Lipsius B. Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/153467.

Council of Science Editors:

Lipsius B. Labor Market Concentration Does Not Explain the Falling Labor Share and Other Essays in Economics. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/153467

University of Michigan

6. Sanders, Jaclyn R. Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars.

Degree: PhD, Physics, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/120826

► The equations of General Relativity admit wave solutions, known as gravitational waves. Gravitational waves have been indirectly detected through observations of the decay of binary… (more)

Subjects/Keywords: gravitational waves; gravitational wave interferometry; multimessenger astronomy; neutron stars; Physics; Science

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APA (6^th Edition):

Sanders, J. R. (2016). Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120826

Chicago Manual of Style (16^th Edition):

Sanders, Jaclyn R. “Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars.” 2016. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/120826.

MLA Handbook (7^th Edition):

Sanders, Jaclyn R. “Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars.” 2016. Web. 20 Apr 2021.

Vancouver:

Sanders JR. Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/120826.

Council of Science Editors:

Sanders JR. Advanced Gravitational Wave Detectors and Detection: Arm Length Stabilization and Directed Searches for Isolated Neutron Stars. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120826

University of Michigan

7. Easley, Kathleen. Simulations and Sensemaking in Elementary Project-Based Science.

Degree: PhD, Educational Studies, 2020, University of Michigan

URL: http://hdl.handle.net/2027.42/155050

► In recent years, there have been many calls for engaging students in sensemaking while interpreting computerized representations. The US Department of Education has called for… (more)

▼ In recent years, there have been many calls for engaging students in sensemaking while interpreting computerized representations. The US Department of Education has called for educators to close the “digital use divide” by supporting all learners to actively engage in sensemaking while working with technology. Literacy scholars have called for students to spend more time working with multimodal, digital, and interactive texts (Dalton & Proctor, 2008; Jewitt, 2008; Kress, 2009). The Next Generation Science Standards have called for students to spend more time interpreting models, including dynamic simulations. All these calls support the integration of computer-based simulations into science instruction. However, we still have much to learn about the enactment of simulation-based lessons in elementary classrooms. In this dissertation study, I investigated the enactment of simulation-based lessons in an elementary project-based science curriculum. The following research questions guided this study: (1) How do teachers support student sensemaking while working with simulations in the context of 3rd grade project-based science? Does this support, or student response to this support, shift across the three simulations? (2) What are the teachers' perspectives regarding the use of simulations as sensemaking tools? This study took place in two third-grade classrooms with a total of 2 teachers and 54 students across a full semester of project-based science instruction. The focal curriculum, Multiple Literacies in Project-based Learning (MLs) integrates science, language arts, and math while addressing all NGSS standards and select CCSS standards. Both teachers were experienced elementary school teachers with prior experience in the ML project. I used case study methods (Dyson & Genishi, 2005; Stake, 1995) to investigate how teachers supported student sensemaking while working with simulations. Data sources for this study included videos of classrooms observations, interviews with teachers, content assessments, artifacts, and the designed curriculum materials. Focal students were selected to represent the range of demographics and reading levels present in each class. With respect to the first research question, findings indicated that teachers used a variety of strategies to support student sensemaking during simulation-based lessons. These included: (a) identifying both conceptual goals and potential learning challenges prior to teaching with the simulation, (b) supporting students to articulate and share observations, predictions, reasoning and claims while working with the simulation, (c) supporting students to plan and conduct investigations using the simulation, (d) supporting students to interpret complex visual representations found within the simulations, (e) supporting student understanding of key scientific concepts, (f) repeating and extending student sensemaking, (g) guiding student use of the simulation by setting specific challenges or goals, (h) publicly recording student learning from the simulations, and (i)… Advisors/Committee Members: Palincsar, Annemarie Sullivan (committee member), Fishman, Barry Jay (committee member), Cervetti, Gina N (committee member), Herrenkohl, Leslie Rupert (committee member).

Subjects/Keywords: sensemaking; simulation; project-based learning; elementary education; literacy education; science education; Education; Social Sciences

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APA (6^th Edition):

Easley, K. (2020). Simulations and Sensemaking in Elementary Project-Based Science. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/155050

Chicago Manual of Style (16^th Edition):

Easley, Kathleen. “Simulations and Sensemaking in Elementary Project-Based Science.” 2020. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/155050.

MLA Handbook (7^th Edition):

Easley, Kathleen. “Simulations and Sensemaking in Elementary Project-Based Science.” 2020. Web. 20 Apr 2021.

Vancouver:

Easley K. Simulations and Sensemaking in Elementary Project-Based Science. [Internet] [Doctoral dissertation]. University of Michigan; 2020. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/155050.

Council of Science Editors:

Easley K. Simulations and Sensemaking in Elementary Project-Based Science. [Doctoral Dissertation]. University of Michigan; 2020. Available from: http://hdl.handle.net/2027.42/155050

University of Michigan

8. Trizila, Patrick Clark. Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions.

Degree: PhD, Aerospace Engineering, 2011, University of Michigan

URL: http://hdl.handle.net/2027.42/86503

► Micro air vehicles (MAVs) are defined by all spatial dimensions being less than 15 cm. Equipped with a video camera or a sensor, these vehicles… (more)

▼ Micro air vehicles (MAVs) are defined by all spatial dimensions being less than 15 cm. Equipped with a video camera or a sensor, these vehicles could perform surveillance and reconnaissance with low rates of detection, or environmental and bio-chemical sensing at remote or otherwise hazardous locations. Its size makes the MAV easily transported and deployed as well as inexpensive and more expendable than alternatives, e.g. an airplane, a satellite, or a human. The ability to hover for an MAV is highly desirable in these contexts. The approach taken in the current studies is to numerically simulate the aerodynamics about flapping wings while controlling the kinematic motions and environmental conditions. Two complementary sets of tools were used in the investigations. Navier-Stokes solvers were used to obtain detailed fluid physics information, instantaneous force data, and to train the surrogate models. The surrogate models were used to estimate the average lift and power required over a flapping cycle while also providing information on the sensitivity of the kinematic variables, to identify trends in lift and power required as a function of the kinematic variables, and to construct a Pareto front showing the trade-offs between the competing objectives. Findings include i) an examination of the competing influences introduced by tip vortices, and it was seen that they could increase lift compared to their analogous 2D cases, counter to classical steady state theory. ii) The highest time averaged lift values were found during kinematics with high angles of attack during advanced rotation as they promoted LEV generation and subsequently took advantage of them during wake capture. iii) Kinematics with synchronized rotation and low angles of attack had surprisingly similar 2D and low-aspect-ratio force histories. iv) Modest environmental perturbations, those a fraction of the translational wing velocity, can have a profound impact on the resulting forces. Closely related open questions regard how the Reynolds number, planform shape, and the flapping about a point, with the resulting centripetal accelerations, affect the LEV and tip vortex development. Particularly what guiding principles should be kept in mind when exploring these degrees of freedom in the context of MAV design? Advisors/Committee Members: Shyy, Wei (committee member), Bernal, Luis P. (committee member), Cesnik, Carlos E. (committee member), Daly, Samantha Hayes (committee member), Friedmann, Peretz P. (committee member), Girard, Anouck Renee (committee member).

Subjects/Keywords: MAV; Aerodynamics; Flapping Wing; Vortex Dynamics; Surrogate Model; Low Reynolds Number; Aerospace Engineering; Engineering

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APA (6^th Edition):

Trizila, P. C. (2011). Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/86503

Chicago Manual of Style (16^th Edition):

Trizila, Patrick Clark. “Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions.” 2011. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/86503.

MLA Handbook (7^th Edition):

Trizila, Patrick Clark. “Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions.” 2011. Web. 20 Apr 2021.

Vancouver:

Trizila PC. Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions. [Internet] [Doctoral dissertation]. University of Michigan; 2011. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/86503.

Council of Science Editors:

Trizila PC. Aerodynamics of Low Reynolds Number Rigid Flapping Wing Under Hover and Freestream Conditions. [Doctoral Dissertation]. University of Michigan; 2011. Available from: http://hdl.handle.net/2027.42/86503

University of Michigan

9. Watkins, Ryan. Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames.

Degree: PhD, Aerospace Engineering, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113455

► Of existing applications, the majority of shape memory alloy (SMA) devices consist of beam (orthodontic wire, eye glasses frames, catheter guide wires) and framed structures… (more)

▼ Of existing applications, the majority of shape memory alloy (SMA) devices consist of beam (orthodontic wire, eye glasses frames, catheter guide wires) and framed structures (cardiovascular stents, vena cava filters). Although uniaxial tension data is often sufficient to model basic beam behavior (which has been the main focus of the research community), the tension-compression asymmetry and complex phase transformation behavior of SMAs suggests more information is necessary to properly model higher complexity states of loading. In this work, SMA beams are experimentally characterized under general loading conditions (including tension, compression, pure bending, and buckling); furthermore, a model is developed with respect to general beam deformation based on the relevant phenomena observed in the experimental characterization. Stress induced phase transformation within superelastic SMA beams is shown to depend on not only the loading mode, but also kinematic constraints imposed by beam geometry (such as beam cross-section and length). In the cases of tension and pure bending, the structural behavior is unstable and corresponds to phase transformation localization and propagation. This unstable behavior is the result of a local level up-down-up stress/strain response in tension, which is measured here using a novel composite – based experimental technique. In addition to unstable phase transformation, intriguing post-buckling straightening is observed in short SMA columns during monotonic loading (termed unbuckling here). Based on this phenomenological understanding of SMA beam behavior, a trilinear based material law is developed in the context of a Shanley column model and is found to capture many of the relevant features of column buckling, including the experimentally observed unbuckling behavior. Due to the success of this model, it is generalized within the context of beam theory and, in conjunction with Bloch wave stability analysis, is used to model and design SMA honeycombs. Advisors/Committee Members: Shaw, John A. (committee member), Daly, Samantha Hayes (committee member), Triantafyllidis, Nicolas (committee member), Grummon, David S. (committee member), Waas, Anthony M. (committee member).

Subjects/Keywords: shape memory alloys (SMAs); beams and frames; NiTi; experimental characterization; constitutive modeling; Aerospace Engineering; Materials Science and Engineering; Mechanical Engineering; Engineering

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APA (6^th Edition):

Watkins, R. (2015). Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113455

Chicago Manual of Style (16^th Edition):

Watkins, Ryan. “Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113455.

MLA Handbook (7^th Edition):

Watkins, Ryan. “Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames.” 2015. Web. 20 Apr 2021.

Vancouver:

Watkins R. Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113455.

Council of Science Editors:

Watkins R. Thermomechanical Characterization and Modeling of Superelastic Shape Memory Alloy Beams and Frames. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113455

10. Hinten, Michael R. An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation.

Degree: PhD, Human Genetics, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/133519

► Abstract Polycomb proteins comprise two major classes of evolutionarily conserved epigenetic transcription repressors, Polycomb repressive complex 2 and 1 (PRC2 and PRC1). PRCs are thought… (more)

▼ Abstract Polycomb proteins comprise two major classes of evolutionarily conserved epigenetic transcription repressors, Polycomb repressive complex 2 and 1 (PRC2 and PRC1). PRCs are thought to catalyze epigenetic silencing via histone modifications and/or physical compaction of the surrounding chromatin. The inactive X-chromosome is a common target of PRCs. X-chromosome inactivation is a paradigmatic epigenetic phenomenon resulting in the equal expression of genes from the X-chromosome between XY male and XX female mammals. The initial form of X-inactivation during murine embryogenesis is imprinted X-inactivation, during which the paternally inherited X-chromosome is preferentially silenced. In my thesis work, I tested the hypothesis that PRC2 proteins orchestrate gene silencing on the paternal X-chromosome during imprinted X-inactivation. To test if PRC2 subunits are required to propagate the X-inactive state, I derived and investigated X-linked gene silencing in mouse trophoblast stem cells (TSCs), an ex vivo model of imprinted X-inactivation. In TSCs lacking the core PRC2 proteins EZH2 and its homologue EZH1, which catalyze trimethylation of histone H3 at lysine 27 (H3-K27me3), I found that X-inactivation was unperturbed. In TSCs lacking EED, which is required for the assembly of PRC2, I found that imprinted X-inactivation was defective. In Eed-/- TSCs, enrichment of H3-K27me3 and the Xist long non-coding RNA, which is required for stable X-inactivation, are lost from the inactive-X. Despite the absence of H3-K27me3 and Xist RNA, only a subset of the genes on the inactive X-chromosome is reactivated in Eed-/- TSCs. Lack of a silencing defect for a majority of X-linked genes in Eed-/- TSCs suggests that factors other than EED, H3-K27me3, and Xist RNA are essential for propagating X-chromosome inactivation. To assess if my findings from TSCs applied in vivo, I generated embryos lacking maternal and zygotic EZH2, or EZH2 and 1, or EED. I discovered that EED, but not EZH2/1, is necessary to trigger imprinted X-inactivation in the embryo. This comparative analysis of PRC2 components suggests a PRC2 independent role for EED in imprinted X-inactivation. Moreover, these results are the initial demonstration that maternal factors control the silencing of the X-chromosome in the embryo, an example of a transgenerational epigenetic regulation. Advisors/Committee Members: Kalantry, Sundeep (committee member), Dou, Yali (committee member), Kim, John (committee member), Burke, David T (committee member).

Subjects/Keywords: Epigenetic Regulation of Mouse Imprinted X-chromosome Inactivation; Genetics; Health Sciences

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APA (6^th Edition):

Hinten, M. R. (2016). An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/133519

Chicago Manual of Style (16^th Edition):

Hinten, Michael R. “An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation.” 2016. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/133519.

MLA Handbook (7^th Edition):

Hinten, Michael R. “An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation.” 2016. Web. 20 Apr 2021.

Vancouver:

Hinten MR. An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/133519.

Council of Science Editors:

Hinten MR. An Analysis of Polycomb Repressive Complex 2 Function Through Imprinted Mouse X-chromosome Inactivation. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/133519

University of Michigan

11. Lemon, Tracie. Public Administrators against Prisoner Reentry and Reintegration.

Degree: Master's, College of Arts and Sciences: Public Administration, 2012, University of Michigan

URL: http://hdl.handle.net/2027.42/117720

► Every year, the criminal justice system releases thousands of offenders back into society, usually into the communities where the offender first committed their crime. Within… (more)

▼ Every year, the criminal justice system releases thousands of offenders back into society, usually into the communities where the offender first committed their crime. Within three years, as many as two-thirds of all released offenders will return to the criminal justice system by means of arrest or incarcerations for new crimes, or recidivating, falling back on the same ciminal behaviors that landed them in the criminal justice program in the first place. Currently there are prisoner reentry programs, such as parole, that exist to help offenders reenter society and not fall back on their criminal behaviors. However, if as many as two-thirds are returning to the criminal justice system, the programs are not working. The offenders are returning to prison and go through the reentry process again. If released offenders are continuing to recidivate, fall back on criminal behaviors, prisoner reentry programs are not working. This study will attempt to identify what factors affect the ability of offenders to complete community supervision programs, such as parole and probation, and what is causing them to be re-incarcerated, or reduce their ability to graduate from their designated reentry program, therefore, jeopardizing their chance at reintegration. Research has found that technical violations, too many strict parole conditions, education, mental illness, drug addictions, and probation officer personalities, lack of employment, or ties to the community lead to the inability of released offenders to complete their parole sentence or graduate from a reentry program. Groups such as the Serious and Violent Offender Reentry Program, Step-Down Program, Preventing Parolee Crime Program, Mental Health and Drug Courts have seen these barriers and have made moves to address them. To confirm the literature collected, the methodology will consist of a summary of Michigan Governer Rick Snyder's Public Safety Plan and a critique of the Plan against collected literature. Advisors/Committee Members: Price, Albert C. (committee member), Schellenberg, Kathryn (committee member), Flint (affiliationumcampus).

Subjects/Keywords: prisoner reentry programs; parole; re-incarceration

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APA (6^th Edition):

Lemon, T. (2012). Public Administrators against Prisoner Reentry and Reintegration. (Masters Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/117720

Chicago Manual of Style (16^th Edition):

Lemon, Tracie. “Public Administrators against Prisoner Reentry and Reintegration.” 2012. Masters Thesis, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/117720.

MLA Handbook (7^th Edition):

Lemon, Tracie. “Public Administrators against Prisoner Reentry and Reintegration.” 2012. Web. 20 Apr 2021.

Vancouver:

Lemon T. Public Administrators against Prisoner Reentry and Reintegration. [Internet] [Masters thesis]. University of Michigan; 2012. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/117720.

Council of Science Editors:

Lemon T. Public Administrators against Prisoner Reentry and Reintegration. [Masters Thesis]. University of Michigan; 2012. Available from: http://hdl.handle.net/2027.42/117720

University of Michigan

12. Sun, Yuqing. The Mechanisms of HOXA9-Mediated Oncogenic Transformation.

Degree: PhD, Molecular & Cellular Pathology, 2017, University of Michigan

URL: http://hdl.handle.net/2027.42/138797

► Hox genes encode a family of homeodomain-containing transcription factors that are critical for body plan specification and tissue morphogenesis during embryonic development. Hoxa9, in particular,… (more)

▼ Hox genes encode a family of homeodomain-containing transcription factors that are critical for body plan specification and tissue morphogenesis during embryonic development. Hoxa9, in particular, is required for adult hematopoiesis in which it promotes stem cell renewal and expansion. Most importantly, Hoxa9 is commonly dysregulated in various types of acute leukemia, including acute myeloid leukemia (AML), and T- and B-precursor acute lymphoblastic leukemia (B-ALL and T-ALL). Together with its co-factor MEIS1, HOXA9 plays a causal role in driving leukemic transformation. Hoxa9 dysregulation is also linked to various types of solid tumors, and both gain and loss of function have been implicated in tumorigenesis. Despite its central role, the mechanism through which HOXA9 mediates oncogenic transformation remains poorly understood. Previous work in our lab found that in a HOXA9/MEIS1-driven AML cell line, HOXA9 primarily binds to promoter-distal regions of the genome. Its target regions predominately carry the epigenetic signatures indicative of active enhancers. A substantial portion of HOXA9 binding sites are co-occupied by lineage-determining factors, such as C/EBPα and PU.1. However, it remains unknown 1) whether HOXA9 drives the formation of active enhancers and globally alters the enhancer landscape; 2) whether HOXA9 strictly acts downstream of other transcription factors, or it can play a pioneer role and acts upstream of all other transcription factors and chromatin regulators; 3) if its regulatory functions are conserved in other cell lineages. To address these questions, I show that in the myeloid lineage, HOXA9/MEIS1-transformed cells are characterized by significant alterations of the enhancer landscape and exhibit prominent emergence of de novo enhancers. These de novo enhancers are absent of enhancer modifications in any hematopoietic cells, and are associated with activation of a leukemia-specific transcription program. HOXA9 acts as a pioneer factor at these de novo regions and is required for the recruitment of myeloid lineage factor C/EBPα while it is dispensable for the formation of the normal hematopoietic enhancers. Together, these results suggest an active role of HOXA9 in altering enhancer landscapes during leukemic transformation. To explore the mechanisms of HOXA9-mediated enhancer formation, I assessed the role of the histone H3K4 methyltransferase MLL3/MLL4 complex in this alteration of enhancer landscape. Using immunoprecipitation and ChIP-seq analysis, I found physical interaction between HOXA9 and the MLL3/MLL4 complex. In addition, I determined that the MLL3/MLL4 complex is required for formation of de novo enhancers, as well as for in vivo leukemogenesis driven by HOXA9/MEIS1. Collectively, these findings provide strong evidence for an essential role for the MLL3/MLL4 complex in HOXA9-mediated leukemic transformation. I have also collected preliminary data pertaining to HOXA9’s function in other cell lineages. I found that HOXA9 localizes to active enhancer regions in B-lineage… Advisors/Committee Members: Dou, Yali (committee member), Hess, Jay L (committee member), Maillard, Ivan Patrick (committee member), Engel, James Douglas (committee member), Figueroa, Maria (committee member), Muntean, Andrew G (committee member).

Subjects/Keywords: HOXA9; enhancers; acute leukemia; Oncology and Hematology; Health Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sun, Y. (2017). The Mechanisms of HOXA9-Mediated Oncogenic Transformation. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/138797

Chicago Manual of Style (16^th Edition):

Sun, Yuqing. “The Mechanisms of HOXA9-Mediated Oncogenic Transformation.” 2017. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/138797.

MLA Handbook (7^th Edition):

Sun, Yuqing. “The Mechanisms of HOXA9-Mediated Oncogenic Transformation.” 2017. Web. 20 Apr 2021.

Vancouver:

Sun Y. The Mechanisms of HOXA9-Mediated Oncogenic Transformation. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/138797.

Council of Science Editors:

Sun Y. The Mechanisms of HOXA9-Mediated Oncogenic Transformation. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/138797

University of Michigan

13. Smith, Broc D. Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene.

Degree: PhD, Chemistry, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/116703

► 7-dehydrocholesterol and stilbene are model systems for the molecules used within the fast-growing field of molecular motors and switches. One of the significant problems facing… (more)

▼ 7-dehydrocholesterol and stilbene are model systems for the molecules used within the fast-growing field of molecular motors and switches. One of the significant problems facing the development of effective motors and switches is the quantum yield of the photoisomerization reactions that these materials undergo. This dissertation describes the use of optical control methods to improve the yields of ring-opening and isomerization of 7-dehydrocholesterol and stilbene following UV excitation. The effects of both single-pulse and two-pulse control schemes using UV and visible excitation pulses were investigated. First, the dependence of the 7-dehydrocholesterol ring-opening on excess vibrational energy was studied by exciting with pump pulses tunable over a broad range of wavelengths. Based on these measurements, it appears that either the vibrational mode in which the excess energy is deposited does not play a role in the ring-opening reaction, or the excess energy is quickly dispersed to the remaining vibrational modes by intramolecular vibrational distribution. Next, the effect of chirp on the dynamics and photoproducts of 7-dehydrocholesterol and cis-stilbene was explored through the use of UV pump pulses with chirp between about 10000 fs2 and 10000 fs2. These experiments showed that there was no measurable change in the amount of photoproduct formed following excitation with these pulses. Finally, a two-pulse pump-repump design was used to first place a population of molecules into the lowest electronic excited state before re-exciting to an even higher state. This technique had little effect on the reaction dynamics of 7-dehydrocholesterol, but successfully modified the isomerization yield for both cis- and trans-stilbene. After the arrival of a visible repump pulse, cis-stilbene showed a small change in reaction dynamics, and the yield of trans-stilbene photoproduct was increased. Trans-stilbene showed a large depletion of the excited state population following repumping, and the yield of cis-stilbene photoproduct was increased. Trans-stilbene also demonstrated a distinct change in the recovery of the ground state population, indicating that the re-excited trans-stilbene molecules utilize a different decay pathway that bypasses the S1 state. These results show that a two-pulse excitation scheme may provide the means to modify the isomerization yield in stilbene based molecular motors. Advisors/Committee Members: Sension, Roseanne J (committee member), Ogilvie, Jennifer P (committee member), Kopelman, Raoul (committee member), Kubarych, Kevin J (committee member).

Subjects/Keywords: Optical Control; Stilbene; 7-dehydrocholesterol; Chemistry; Science

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APA (6^th Edition):

Smith, B. D. (2015). Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/116703

Chicago Manual of Style (16^th Edition):

Smith, Broc D. “Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/116703.

MLA Handbook (7^th Edition):

Smith, Broc D. “Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene.” 2015. Web. 20 Apr 2021.

Vancouver:

Smith BD. Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/116703.

Council of Science Editors:

Smith BD. Ultrafast Optical Control of Ring-Opening and Isomerization in 7-Dehydrocholesterol and Stilbene. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/116703

University of Michigan

14. Weskamp, Kaitlin. Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis.

Degree: PhD, Neuroscience, 2019, University of Michigan

URL: http://hdl.handle.net/2027.42/153387

► Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder in which the progressive loss of motor neurons results in paralysis and respiratory failure. Though the… (more)

▼ Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder in which the progressive loss of motor neurons results in paralysis and respiratory failure. Though the study of ALS is complicated by its heterogeneous biochemical, genetic, and clinical features, dysregulation of the RNA-binding protein TDP43 is observed in the vast majority of ALS cases. Although TARDBP mutations account for only a small proportion of the disease burden (2-5%), cytoplasmic TDP43 mislocalization and accumulation are observed in >90% of individuals with ALS. Moreover, mutations in several other ALS-associated genes result in TDP43 pathology. TDP43 is an essential protein involved in several RNA processing events, including splicing, translation, and degradation, and small changes in its localization and expression level are sufficient to disrupt critical cell processes (Chapter 1). As such, accumulating evidence implicates TDP43 and TDP43-dependent RNA processing in neurodegenerative disease (Chapter 2), but drivers of TDP43 accumulation and mislocalization remain fundamentally unclear. Here, we seek to identify phenomena that initiate TDP43 dyshomeostasis and develop techniques to better monitor TDP43 metabolism in the context of ALS. Much like TDP43 pathology, neuronal hyperexcitability is a conserved feature observed in both familial and sporadic ALS. However, its relation to neurodegeneration and TDP43 deposition in disease remains unknown. In Chapter 3, we show that hyperexcitability recapitulates TDP43 pathology by upregulating shortened (s) TDP43 splice isoforms. These truncated isoforms accumulate in the cytosol, where they form insoluble inclusions that sequester full-length TDP43 via preserved N-terminal interactions. Consistent with these findings, sTDP43 overexpression is toxic to mammalian neurons, suggesting that neurodegeneration results from complementary gain- and loss-of-function mechanisms. In humans and mice, sTDP43 transcripts are enriched in vulnerable motor neurons, and we observed a striking accumulation of sTDP43 within neurons and glia of ALS patients. These studies uncover a hitherto unknown role of alternative TDP43 isoforms, and indicate that sTDP43 production may be a key contributor to the susceptibility of motor neurons in ALS. In Appendix A, we establish a technique to monitor TDP43 metabolism at the endogenous level. To do so, we developed induced pluripotent stem cell (iPSC)-derived neurons in which we can monitor the synthesis and degradation of native TDP43 in a non-invasive manner. Following these measurements, each neuron is tracked over time to determine its time of death via longitudinal fluorescence microscopy (Appendix B), enabling us to determine how TDP43 synthesis and decay rates impact neuronal survival. Future work can utilize this methodology to determine if TDP43 metabolism is altered in neurons derived from ALS patients with C9orf72 and TARDBP mutations to further elucidate mechanisms of TDP43 dyshomeostasis. Chapter 4 concludes the dissertation and describes… Advisors/Committee Members: Barmada, Sami J (committee member), Murphy, Geoffrey G (committee member), Parent, Jack M (committee member), Todd, Peter (committee member), Uhler, Michael D (committee member).

Subjects/Keywords: TDP43; ALS; hyperexcitability; alternative splicing; TDP43 pathology; iPSC; Neurosciences; Health Sciences; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Weskamp, K. (2019). Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/153387

Chicago Manual of Style (16^th Edition):

Weskamp, Kaitlin. “Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis.” 2019. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/153387.

MLA Handbook (7^th Edition):

Weskamp, Kaitlin. “Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis.” 2019. Web. 20 Apr 2021.

Vancouver:

Weskamp K. Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/153387.

Council of Science Editors:

Weskamp K. Drivers of TDP43 Dyshomeostasis in Amyotrophic Lateral Sclerosis. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/153387

University of Michigan

15. Lu, William. Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function.

Degree: PhD, Cellular and Molecular Biology, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113621

► The generation of antigen receptors requires a gene rearrangement process known as V(D)J recombination. Double stranded breaks produced during recombination must be repaired by the… (more)

▼ The generation of antigen receptors requires a gene rearrangement process known as V(D)J recombination. Double stranded breaks produced during recombination must be repaired by the nonhomologous end joining pathway. One critical factor important for this recombination event is the Artemis nuclease, which processes the DNA ends before ligation. Patients with mutations affecting the catalytic N-terminal domain of Artemis are radiosensitive and do not produce B and T cells. Hypomorphic Artemis mutations involving the nonconserved C-terminus have also been described. These patients have a partial B and T cell deficiency but exhibit a predisposition to lymphoid malignancies. Here, I study the regulation of the Artemis nuclease during V(D)J recombination and the genetic interactions between the Artemis C-terminal domain and DNA damage inducible protein kinase, ATM. I define a region in the C-terminus that is required for endonucleolytic activity and preventing aberrant V(D)J recombination. The findings presented here also suggest that there may be previously undescribed regulatory features located in the Artemis N-terminus that are separate from catalytic activity. To analyze the in vivo consequences resulting from the loss of the Artemis C-terminus, I utilized a hypomorphic Artemis mouse model harboring an allele that results in C-terminal truncation, Artemis-P70. Cellular and in vivo assays suggest that the Artemis C-terminus and the ATM kinase cooperate to facilitate V(D)J recombination and loss of both factors can result in a lymphocyte deficiency that is more severe than in mice deficient for one factor. Although ATM deficient mice succumb to thymic lymphoma, mice harboring homozygous mutations in both Artemis-P70 and ATM are surprisingly tumor-free. These mice, however, had inflamed colons with T cell and neutrophil infiltration. These findings together emphasize the importance of the regulatory domains of Artemis. A disregulated nuclease can facilitate aberrant recombination and that can disrupt proper lymphocyte development. A lymphocyte defect may operate in concert with other factors such as DNA repair deficiency and cytokine imbalance which together could promote chronic inflammation. Finally, results presented here suggest that there may be other means of Artemis regulation that are dependent on features located in the conserved N-terminal domain. Advisors/Committee Members: Sekiguchi, Joann (committee member), Canman, Christine (committee member), Chan, Raymond C. (committee member), Ljungman, Mats E D (committee member), Meek, Katheryn (committee member).

Subjects/Keywords: Artemis; V(D)J recombination; Nonhomologous end joining; Molecular, Cellular and Developmental Biology; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lu, W. (2015). Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113621

Chicago Manual of Style (16^th Edition):

Lu, William. “Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113621.

MLA Handbook (7^th Edition):

Lu, William. “Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function.” 2015. Web. 20 Apr 2021.

Vancouver:

Lu W. Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113621.

Council of Science Editors:

Lu W. Consequence of a Hypomorphic Artemis Mutation on V(D)J Recombination and Proper Immune Function. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113621

University of Michigan

16. Gamboa, Thomas. Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals.

Degree: AMU, Music: Conducting, 2018, University of Michigan

URL: http://hdl.handle.net/2027.42/143910

► The following dissertation recitals included music from the Renaissance to the present. Compositions for both large and chamber ensembles were represented. Each of the three… (more)

▼ The following dissertation recitals included music from the Renaissance to the present. Compositions for both large and chamber ensembles were represented. Each of the three recitals had created an underlying theme; the first recital as Inspirations, the second recital as Reflections, and the third recital as Musical Forms: The Road Map of Expression. The first recital, Inspirations, was a collection of performances with the University of Michigan Symphony Band, Symphony Band Chamber Winds, and Concert Band, which took place during the 2016–2017 academic year. Works for this recital, which examined the various motives and muses that stimulated the composers’ ideas, consisted of the following works: Reflections on a Sixteenth-Century Tune by Richard Rodney Bennett; Chester: Overture for Band by William Schuman; Dreamcatcher by Walter Mays; and Partita in B-flat Major, op. 67 by Franz Krommer. The second recital, Reflections, was a compilation of performances presented throughout fall 2017. Three of the performances were with the University of Michigan Symphony Band and Symphony Band Chamber Winds, while the remaining two pieces were part of an ad hoc performance in Britton Recital Hall on Thursday, October 26, 2017. Works for this recital, which represented the composers, their thoughts, and surroundings, consisted of the following: Three Dances and Final Scene from Der Mond by Carl Orff arranged by Friedrich Wanek; Trauermusik, WWV 73 by Richard Wagner; cheating, lying, stealing by David Lang; Aria della battaglia by Andrea Gabrieli; Octet by Igor Stravinsky. The final recital, Musical Forms: The Road Map of Expression, took place as an ad hoc performance in the McIntosh Theatre on Sunday, January 21, 2018. The works on the recital, which illustrated the use of traditional musical forms underlying developments in harmonic language, consisted of the following: Overture from the Music for the Royal Fireworks, HWV 351 by George Frideric Handel; Concerto for Cello and Wind Ensemble by Daron Aric Hagen; Octet, op. 216 by Carl Reinecke. Advisors/Committee Members: Haithcock, Michael L (committee member), Wakefield, Gregory H (committee member), Heneghan, Aine (committee member), Porter, Amy K (committee member), Snyder, Courtney Kristen (committee member).

Subjects/Keywords: Music Wind Band Bennett Schuman Mays Krommer Orff Wagner Lang Gabrieli Stravinsky Handel Hagen Reinecke; Music and Dance; Arts

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APA (6^th Edition):

Gamboa, T. (2018). Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals. (Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/143910

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gamboa, Thomas. “Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals.” 2018. Thesis, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/143910.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gamboa, Thomas. “Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals.” 2018. Web. 20 Apr 2021.

Vancouver:

Gamboa T. Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals. [Internet] [Thesis]. University of Michigan; 2018. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/143910.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gamboa T. Wind Music from the Renaissance to the Present: A Summary of Dissertation Recitals. [Thesis]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/143910

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Michigan

17. Melnysyn, Shana. Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910.

Degree: PhD, Anthropology and History, 2017, University of Michigan

URL: http://hdl.handle.net/2027.42/138655

► At the end of the nineteenth century, Angola was ostensibly “Portuguese.” But colonial settlement and bureaucracy in the south central African territory were limited to… (more)

▼ At the end of the nineteenth century, Angola was ostensibly “Portuguese.” But colonial settlement and bureaucracy in the south central African territory were limited to the Atlantic ports of Luanda and Benguela and a few small military outposts in the hinterland. The transatlantic slave trade had brought an influx of novel commodities and people to Angola’s shores since the end of the fifteenth century, gradually transforming the modes through which people defined identities and loyalties. Against the notion that a “slaving frontier” moved steadily inland and left relative stability in its wake, this dissertation shows how a diverse patchwork of political structures and authorities persisted into the twentieth century, confounding metropolitan Portuguese agents. Following Vellut’s articulation of a “lusoafrican frontier, some historians have grouped the motley mix of exiles from Portugal who ran off into the bush, mestiços born of their local liaisons, and black Angolans adopting Portuguese language, dress, and religion as “Luso-Africans.” While this classification performed useful work in previous histories of Angola, I argue that we should only use it carefully and critically, giving preference to emic categories to broaden the descriptive range. Locally forged categories of people— intermediary traders and scribes such as Ambaquistas and Mambari—performed and disseminated colonial authority from an early date by building trade networks deep into the continent. Their social and racial fluidity enabled them to navigate political and commercial networks with ease and diplomacy, bridging worlds. Luso-Africans and colonial agents had to contend with existing idioms of power recognized by people whom the state classified as gentio (unassimilated “gentiles”) well into the twentieth century. These gentio frequently rejected colonial influence through violent uprisings such as the Mbailundu Revolt of 1902—one of the largest in Angolan history and an important conflict that has received relatively scant attention from researchers. Political elites from the Mbailundu Kingdom in Angola’s mostly Umbunduspeaking central highlands targeted Luso-African traders and Portuguese colonial agents, suggesting they were attempting to draw stricter boundaries between subjects of Mbailundu and all others who did not belong in their territory. Contributing to scholarly debates on Portuguese colonial power as “weak” or “subaltern,” this dissertation shows how traders of indigenous and mixed descent circulated European objects and affects, spreading colonial aesthetics and logics. Despite the dearth of Portuguese institutions such as schools, courts, or missions throughout most of the vast territory of Angola, these new players created their own niche. When the Mbailundu Revolt broke out in 1902, local elites defending “traditional” authority targeted intermediaries and Europeans as threatening outsiders who would no longer be tolerated. Portuguese authorities condemned Luso-African traders as instigators who stoked moral outrage. The state… Advisors/Committee Members: Hunt, Nancy Rose (committee member), Ashforth, Adam Philip (committee member), Askew, Kelly M (committee member), Johnson, Paul Christopher (committee member), Pitcher, Anne (committee member).

Subjects/Keywords: Portuguese colonialism; Racial identity & "creolization"; Anticolonial rebellion; History (General); African Studies; Anthropology and Archaeology; Humanities; Social Sciences

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APA (6^th Edition):

Melnysyn, S. (2017). Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/138655

Chicago Manual of Style (16^th Edition):

Melnysyn, Shana. “Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910.” 2017. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/138655.

MLA Handbook (7^th Edition):

Melnysyn, Shana. “Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910.” 2017. Web. 20 Apr 2021.

Vancouver:

Melnysyn S. Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/138655.

Council of Science Editors:

Melnysyn S. Vagabond States: Boundaries and Belonging in Portuguese Angola, c. 1880-1910. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/138655

University of Michigan

18. Gelman, Michael. Understanding Household Consumption and Saving Behavior using Account Data.

Degree: PhD, Economics, 2017, University of Michigan

URL: http://hdl.handle.net/2027.42/138492

► The first chapter examines the result that cash on hand is the most important source of variation in explaining heterogeneity in the marginal propensity to… (more)

▼ The first chapter examines the result that cash on hand is the most important source of variation in explaining heterogeneity in the marginal propensity to consume (MPC). While the standard hypothesis is that differences in financial circumstances caused by temporary income shocks explain this result, this paper finds that differences across persistent characteristics are just as important. To reach this finding, this paper develops a buffer stock model with discount factor heterogeneity and estimates it using a novel panel data set from a personal finance app that jointly measures spending, income, and liquid assets. In the model, within-individual variation in cash on hand results from temporary income shocks while across-individual variation in cash on hand results from differences in persistent characteristics. The panel nature of the data separately identifies temporary and persistent drivers of the MPC while previous studies using cross-sectional data typically confound these concepts. Simulations from the estimated model imply that ignoring heterogeneity in persistent characteristics leads to underestimating the aggregate MPC. The second chapter examines how individuals adjusted spending and saving in response to a temporary drop in income due to the 2013 U.S. government shutdown. The shutdown cut paychecks by 40% for affected employees, which was recovered within 2 weeks. Because it affected only the timing of payments, the shutdown provides a distinct experiment allowing estimates of the response to a liquidity shock holding income constant. Spending dropped sharply implying a naive estimate of the marginal propensity to spend of 0.58. This estimate overstates how consumption responded. While many individuals had low liquidity, they used multiple strategies to smooth consumption including delay of recurring payments such as mortgages and credit card balances. This is joint with Shachar Kariv, Matthew D. Shapiro, Dan Silverman, and Steven Tadelis. The third chapter estimates how overall consumer spending responds to changes in gasoline prices. It uses the differential impact across consumers of the sudden, large drop in gasoline prices in 2014 for identification. This estimation strategy is implemented using comprehensive, daily transaction-level data for a large panel of individuals. The estimated marginal propensity to consume (MPC) is approximately one, a higher estimate than that found in less comprehensive or well-measured data. This estimate takes into account the elasticity of demand for gasoline and potential slow adjustment to changes in prices. The high MPC implies that changes in gasoline prices have large aggregate effects. This is joint with Yuriy Gorodnichenko, Shachar Kariv, Dmitri Koustas, Matthew D. Shapiro, Dan Silverman, and Steven Tadelis. The fourth chapter examines the response of food expenditures to the receipt of paychecks using financial account data from a personal finance app. Similar to previous studies, this paper finds that food expenditures increase during the week the… Advisors/Committee Members: Shapiro, Matthew D (committee member), Schmalz, Martin C (committee member), Leahy, John (committee member), Stephens Jr, Melvin (committee member).

Subjects/Keywords: household finance; big data; Economics; Business and Economics

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APA (6^th Edition):

Gelman, M. (2017). Understanding Household Consumption and Saving Behavior using Account Data. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/138492

Chicago Manual of Style (16^th Edition):

Gelman, Michael. “Understanding Household Consumption and Saving Behavior using Account Data.” 2017. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/138492.

MLA Handbook (7^th Edition):

Gelman, Michael. “Understanding Household Consumption and Saving Behavior using Account Data.” 2017. Web. 20 Apr 2021.

Vancouver:

Gelman M. Understanding Household Consumption and Saving Behavior using Account Data. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/138492.

Council of Science Editors:

Gelman M. Understanding Household Consumption and Saving Behavior using Account Data. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/138492

University of Michigan

19. Ajdaroski, Mirel. Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing.

Degree: MSin Engineering, Bioengineering, College of Engineering & Computer Science, 2020, University of Michigan

URL: http://hdl.handle.net/2027.42/154871

► Participation in sports has been on the rise in the last few years, and while regular activity in sports has many benefits, there is always… (more)

Subjects/Keywords: Internal measurement units; Anterior cruciate ligament; ACL injury; Sports medicine; Biomedical engineering

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APA (6^th Edition):

Ajdaroski, M. (2020). Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing. (Masters Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/154871

Chicago Manual of Style (16^th Edition):

Ajdaroski, Mirel. “Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing.” 2020. Masters Thesis, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/154871.

MLA Handbook (7^th Edition):

Ajdaroski, Mirel. “Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing.” 2020. Web. 20 Apr 2021.

Vancouver:

Ajdaroski M. Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing. [Internet] [Masters thesis]. University of Michigan; 2020. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/154871.

Council of Science Editors:

Ajdaroski M. Validation of an Internal Measurement Unit to Measure Knee Kinematics and ACL Fatigue in Cadaveric Specimens During Simulated One-Legged Landing. [Masters Thesis]. University of Michigan; 2020. Available from: http://hdl.handle.net/2027.42/154871

University of Michigan

20. Richardson, Donald. Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers.

Degree: PhD, Industrial & Operations Engineering, 2019, University of Michigan

URL: http://hdl.handle.net/2027.42/151706

► Outpatient chemotherapy infusion is one of the most common forms of treatment used to cure, control, and ease symptoms of cancer. Patients who require outpatient… (more)

▼ Outpatient chemotherapy infusion is one of the most common forms of treatment used to cure, control, and ease symptoms of cancer. Patients who require outpatient chemotherapy infusion undergo lengthy and physically demanding infusion sessions over the course of their treatment. While the frequency and duration of visits vary by patient, drug, and cancer type, most patients will require several treatments over the course of months or years to complete their regimen/treat their disease. Receiving infusion is just one part of the complex treatment process. Patients may have their blood work done, wait for the results to process, visit their oncologist, wait on their order to be placed by their oncologist and prepared by the pharmacy, and then have the infusion administered by infusion clinic staff. Each step introduces randomness which can lead to propagated delays. These delays negatively affect patients as well as clinical operation cost and staff workload. We focus on optimizing drug preparation at the pharmacy to reduce patient delays. Drugs can be prepared the morning before patients arrive to prevent the patient from waiting the additional time needed to prepare their prescribed drugs in addition to any other wait time incurred during peak pharmacy hours. However, patients scheduled for outpatient chemotherapy infusion sometimes may need to cancel at the last minute even after arriving for their appointment (i.e. patient may be deemed too ill to receive treatment). This results in the health system incurring waste cost if the drug was made ahead since the drugs are patient specific and have a short shelf life. Infusion centers must implement policies to balance this potential waste cost with the time savings for their patients and staff. In support of this effort, this dissertation focuses on methods and strategies to improve the process flow of chemotherapy infusion outpatients by optimizing pharmacy make-ahead policies. We propose using three different methods which build upon each other. First we develop a predictive model which utilizes patient-specific data to estimate the probability that a patient will defer or not show for treatment on a given day. Generally, the ability to generate high-quality predictions of patient deferrals can be highly valuable in managing clinical operations, such as scheduling patients, determining which drugs to make before patients arrive, and establishing the proper staffing for a given day. We also introduce how the patient-specific probability of deferral can help determine a ``general rule of thumb" policy for what should be made ahead on a given day. Next we utilize these probabilities in two integer programming models. These multi-criteria optimization models prioritize which and how many drugs to make ahead given a fixed window of time. This is done with the dual objectives of reducing the expected waste cost as well as the expected value of reduced patient waiting time. Lastly, we utilize simulation to better quantify the impact of our proposed policies. We show that… Advisors/Committee Members: Cohn, Amy Ellen Mainville (committee member), Prosser, Lisa (committee member), Guikema, Seth David (committee member), Lavieri, Mariel (committee member).

Subjects/Keywords: Linear Integer Programming, Simulation, Predictive Modeling, Cancer Center Pharmacy; Industrial and Operations Engineering; Engineering

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APA (6^th Edition):

Richardson, D. (2019). Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/151706

Chicago Manual of Style (16^th Edition):

Richardson, Donald. “Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers.” 2019. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/151706.

MLA Handbook (7^th Edition):

Richardson, Donald. “Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers.” 2019. Web. 20 Apr 2021.

Vancouver:

Richardson D. Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/151706.

Council of Science Editors:

Richardson D. Operations Research Frameworks for Improving Make-Ahead Drug Policies at Outpatient Chemotherapy Infusion Centers. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/151706

21. Kickert, Conrad Christiaan. Active Centers - Interactive Edges.

Degree: PhD, Architecture, 2014, University of Michigan

URL: http://hdl.handle.net/2027.42/110405

► This dissertation explores the deteriorating relationship between architecture and public space plaguing many Western urban cores as a result of economic, cultural, political and social… (more)

▼ This dissertation explores the deteriorating relationship between architecture and public space plaguing many Western urban cores as a result of economic, cultural, political and social forces. It investigates the question of how and why ground floor frontages have been transformed, by comparing the urban cores of The Hague (Netherlands) and Detroit (United States) over the past century. Frontage interactivity is defined as the combination of physical transparency, functional permeability and perceptual hospitality, and is mapped in both urban cores over the span of a century in 10 to 25 year intervals. Interactivity is categorized into four tiers, based on fourteen functional frontage types, ranging from highly interactive retail businesses to dwellings and less interactive offices, parking structures and warehouses. Patterns of physical and functional fringe belt formation and urban erosion are found in the maps and statistical analyses. These analyses demonstrate a pattern of fringe interactivity decline, amplified by an acceleration of decline at the level of the street segment – pointing to the contagion of vacancy and inactive land uses. This interactivity erosion is usually followed and amplified by a rapid morphological change, often fueled by large-scale urban renewal interventions – a pattern that is surprisingly similar in both cities. The forces behind frontage transformation are illustrated by separate histories of The Hague and Detroit. The demonstrated forces and patterns of change are integrated into a set of conclusions, finding significant similarities between both case studies. From an economic, social and cultural perspective both cities have faced and still face similar challenges, albeit amplified in Detroit. The relationship between buildings and public space has deteriorated significantly in downtown Detroit as a result of socio-economic decline, amplified by a culture favoring progress over sustaining a collective memory. The Hague’s inner city has benefited from a somewhat finer balance between progress and permanence, often due to fierce public and political debates. The conclusions are followed by a set of recommendations for how to counter frontage deactivation, focusing on the role of economics, diversity, curbing fear and auto-mobility, and critical mass in reshaping the architecture of public life. Advisors/Committee Members: Fishman, Robert L. (committee member), Groat, Linda N. (committee member), Thomas, June Manning (committee member), Bekkering, Hendrik Cornelis (committee member).

Subjects/Keywords: Interactive frontages; Downtown Detroit; Inner city The Hague; Urban morphology; Urban design; Architecture; Urban Planning; Arts; Social Sciences

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APA (6^th Edition):

Kickert, C. C. (2014). Active Centers - Interactive Edges. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/110405

Chicago Manual of Style (16^th Edition):

Kickert, Conrad Christiaan. “Active Centers - Interactive Edges.” 2014. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/110405.

MLA Handbook (7^th Edition):

Kickert, Conrad Christiaan. “Active Centers - Interactive Edges.” 2014. Web. 20 Apr 2021.

Vancouver:

Kickert CC. Active Centers - Interactive Edges. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/110405.

Council of Science Editors:

Kickert CC. Active Centers - Interactive Edges. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/110405

University of Michigan

22. Sowden, Walter James. Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning.

Degree: PhD, Psychology, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113467

► What factors determine how people decide whether a behavior is right or wrong, good or bad, moral or immoral? Over the past decade-and-a-half, moral psychologists… (more)

Subjects/Keywords: Moral judgment and decision making; Interpersonal relationships; Moral regulaiton; Moral self-control; Psychology; Social Sciences

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APA (6^th Edition):

Sowden, W. J. (2015). Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113467

Chicago Manual of Style (16^th Edition):

Sowden, Walter James. “Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113467.

MLA Handbook (7^th Edition):

Sowden, Walter James. “Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning.” 2015. Web. 20 Apr 2021.

Vancouver:

Sowden WJ. Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113467.

Council of Science Editors:

Sowden WJ. Self-Distance Mitigates the Effect of Close Relationships on Moral Reasoning. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113467

University of Michigan

23. Oyler, Dave Wilson. Contributions To Pursuit-Evasion Game Theory.

Degree: PhD, Aerospace Engineering, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/120650

► This dissertation studies adversarial conflicts among a group of agents moving in the plane, possibly among obstacles, where some agents are pursuers and others are… (more)

▼ This dissertation studies adversarial conflicts among a group of agents moving in the plane, possibly among obstacles, where some agents are pursuers and others are evaders. The goal of the pursuers is to capture the evaders, where capture requires a pursuer to be either co-located with an evader, or in close proximity. The goal of the evaders is to avoid capture. These scenarios, where different groups compete to accomplish conflicting goals, are referred to as pursuit-evasion games, and the agents are called players. Games featuring one pursuer and one evader are analyzed using dominance, where a point in the plane is said to be dominated by a player if that player is able to reach the point before the opposing players, regardless of the opposing players' actions. Two generalizations of the Apollonius circle are provided. One solves games with environments containing obstacles, and the other provides an alternative solution method for the Homicidal Chauffeur game. Optimal pursuit and evasion strategies based on dominance are provided. One benefit of dominance analysis is that it extends to games with many players. Two foundational games are studied; one features multiple pursuers against a single evader, and the other features a single pursuer against multiple evaders. Both are solved using dominance through a reduction to single pursuer, single evader games. Another game featuring competing teams of pursuers is introduced, where an evader cooperates with friendly pursuers to rendezvous before being captured by adversaries. Next, the assumption of complete and perfect information is relaxed, and uncertainties in player speeds, player positions, obstacle locations, and cost functions are studied. The sensitivity of the dominance boundary to perturbations in parameters is provided, and probabilistic dominance is introduced. The effect of information is studied by comparing solutions of games with perfect information to games with uncertainty. Finally, a pursuit law is developed that requires minimal information and highlights a limitation of dominance regions. These contributions extend pursuit-evasion game theory to a number of games that have not previously been solved, and in some cases, the solutions presented are more amenable to implementation than previous methods. Advisors/Committee Members: Girard, Anouck Renee (committee member), Bloch, Anthony M (committee member), Kabamba, Pierre Tshimanga (committee member), Inman, Daniel J (committee member), Kolmanovsky, Ilya Vladimir (committee member).

Subjects/Keywords: Pursuit-Evasion Games; Adversarial Games; Dominance Regions; Multi-Agent Systems; Autonomous Mobile Robotics; Homing Guidance; Aerospace Engineering; Engineering (General); Engineering

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APA (6^th Edition):

Oyler, D. W. (2016). Contributions To Pursuit-Evasion Game Theory. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120650

Chicago Manual of Style (16^th Edition):

Oyler, Dave Wilson. “Contributions To Pursuit-Evasion Game Theory.” 2016. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/120650.

MLA Handbook (7^th Edition):

Oyler, Dave Wilson. “Contributions To Pursuit-Evasion Game Theory.” 2016. Web. 20 Apr 2021.

Vancouver:

Oyler DW. Contributions To Pursuit-Evasion Game Theory. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/120650.

Council of Science Editors:

Oyler DW. Contributions To Pursuit-Evasion Game Theory. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120650

24. Kim, Jiyoon. Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households.

Degree: PhD, Economics, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113362

► The overarching theme of the dissertation is to examine the impacts of government assistance programs on the economic behaviors of disadvantaged groups such as low-income… (more)

Subjects/Keywords: Poverty; Welfare program; Temporary Assistance for Needy Families (TANF); Supplemental Nutrition Assistance Program (SNAP); Program valuation; Social safety net; Social Sciences (General); Social Sciences

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APA (6^th Edition):

Kim, J. (2015). Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113362

Chicago Manual of Style (16^th Edition):

Kim, Jiyoon. “Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113362.

MLA Handbook (7^th Edition):

Kim, Jiyoon. “Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households.” 2015. Web. 20 Apr 2021.

Vancouver:

Kim J. Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113362.

Council of Science Editors:

Kim J. Three Essays on the Impact of Government Assistance Programs on Economic Behaviors of Vulnerable Households. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113362

University of Michigan

25. Leon, Evan. An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs.

Degree: MS, School for Environment and Sustainability, 2020, University of Michigan

URL: http://hdl.handle.net/2027.42/154776

► Current lithium-ion battery (LiB) recycling infrastructure is limited for strategic metals such as lithium and cobalt, despite projections that millions of electric vehicles (EVs) will… (more)

Subjects/Keywords: metals; recycling; sustainability; lithium-ion batteries; electric vehicles

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APA (6^th Edition):

Leon, E. (2020). An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs. (Masters Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/154776

Chicago Manual of Style (16^th Edition):

Leon, Evan. “An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs.” 2020. Masters Thesis, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/154776.

MLA Handbook (7^th Edition):

Leon, Evan. “An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs.” 2020. Web. 20 Apr 2021.

Vancouver:

Leon E. An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs. [Internet] [Masters thesis]. University of Michigan; 2020. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/154776.

Council of Science Editors:

Leon E. An Applied Analysis of the Recyclability of Electric Vehicle Battery Packs. [Masters Thesis]. University of Michigan; 2020. Available from: http://hdl.handle.net/2027.42/154776

University of Michigan

26. Weberg, Micah. Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes.

Degree: PhD, Atmospheric, Oceanic and Space Sciences, 2015, University of Michigan

URL: http://hdl.handle.net/2027.42/113476

► Heavy ions in the solar wind record the history of physical events occurring to a given parcel of plasma during its escape from the solar… (more)

▼ Heavy ions in the solar wind record the history of physical events occurring to a given parcel of plasma during its escape from the solar atmosphere. Heating, acceleration, and interactions with waves, particles, and magnetic fields all imprint their signatures in the elemental composition and ionic charge states of heavy ions which carry the information unchanged from a few solar radii all the way to the edge of the heliosphere. Therefore by studying heavy ions in the solar wind near-Earth, we are able to peer back into the corona and gain valuable insight concerning physical processes within a region currently inaccessible to direct satellite exploration. Understanding how mass and energy is released from the Sun and transported into interplanetary space is of increasing importance to our modern society which depends on space-based technology for global navigation and communications. In this work we explore the source regions, release and acceleration mechanisms, and elemental fractionation of the slow solar wind. In particular we seek to answer the following questions: (1) “How much plasma, if any, do the largest coronal loops contribute to the solar wind?”, (2) “Where and how does closed filed plasma escape into the solar wind and become accelerated?”, and (3) “What are the physical conditions and time scales required for gravitational settling?”. Towards these ends, we delve into over 20 years of solar wind data from two nearly identical Solar Wind Ion Composition Spectrometer (SWICS) instruments which flew onboard the Ulysses (1990 – 2009) and Advanced Composition Explorer (ACE; 1998 - present) spacecraft. We utilize novel analysis methods and discover the existence of a new class of solar wind events which we call “heavy ion dropouts”. These dropouts have distinctive, mass-fractionated elemental composition indicative of specific coronal conditions and probable source regions. By analyzing the temporal and spatial variability of heavy ion dropouts and comparing our observations to basic simulations of the solar corona, we are able to provide fresh insight which may be used to constrain, validate, and refine prevailing solar wind theories. Advisors/Committee Members: Lepri, Susan Therese (committee member), Zurbuchen, Thomas H. (committee member), Kushner, Mark (committee member), Landi, Enrico (committee member).

Subjects/Keywords: Solar Wind; Corona; Sun; Heliophysics; Atmospheric, Oceanic and Space Sciences; Science

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APA (6^th Edition):

Weberg, M. (2015). Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/113476

Chicago Manual of Style (16^th Edition):

Weberg, Micah. “Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes.” 2015. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/113476.

MLA Handbook (7^th Edition):

Weberg, Micah. “Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes.” 2015. Web. 20 Apr 2021.

Vancouver:

Weberg M. Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes. [Internet] [Doctoral dissertation]. University of Michigan; 2015. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/113476.

Council of Science Editors:

Weberg M. Elemental Fractionation of the Solar Wind as Indicators of Coronal Source Regions and Physical Processes. [Doctoral Dissertation]. University of Michigan; 2015. Available from: http://hdl.handle.net/2027.42/113476

University of Michigan

27. Szymanski, Melissa. Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI.

Degree: MS, Biology, 2016, University of Michigan

URL: http://hdl.handle.net/2027.42/136883

► When implementing management decisions managers should utilize the most cost-effective strategies that also provide the most benefit for the managed species. There are many different… (more)

▼ When implementing management decisions managers should utilize the most cost-effective strategies that also provide the most benefit for the managed species. There are many different management options to consider when the objective is conservation of long lived reptiles (e.g., turtles) with one of them being headstarting. Headstarting is when reptile eggs are collected by managers, hatched in captivity, and hatchlings are raised for a certain time before being released into their native habitat. Blanding’s Turtles (Emydoidea blandingii) are a state species of special concern in Michigan, where this study takes place. Headstarted Blanding’s Turtles were raised for one and a half years and should benefit from being released in a suitable microhabitat within a wetland. This study’s aim was to investigate the success of varying release locations and the headstart program by measuring thermoregulation patterns, survival, and movements of juvenile headstarted Blanding’s Turtles. During June 2014, twenty-four Blanding’s Turtles were released and tracked for eighteen months using radio telemetry to measure survival and to look at the movements among microhabitats; water and carapace temperature data were used to measure thermoregulation patterns. The headstarted juvenile Blanding’s Turtles had an average carapace temperature lower than adults from previous studies and used basking as a thermoregulatory behavior. To evaluate factors that may potentially affect survival of Blanding’s Turtles microhabitat factors at turtle relocation points within Shiawassee National Wildlife Refuge, Saginaw, MI, USA were recorded, including water depth, vegetation type and dominance, substrate depth, and air and water temperature. GIS and ground truth data were used to investigate microhabitat factors and map turtle locations. All of the headstarted Blanding’s Turtles survived overwintering through spring 2015. Turtles were released in four different locations with different microhabitats. Minimum convex polygon home ranges and movement patterns were analyzed to see if differences occurred across release groups and age classes. Significant differences were found between turtle home range size per release group. Comparisons to studies on wild-hatched Blanding’s Turtles were made and showed that these headstarted Blanding’s Turtles behaved similar to their wild-hatched counterparts when comparing behaviors at relocations and home range sizes. Use versus availability showed that the juvenile headstarted Blanding’s Turtles avoided open water, willows, and lowland forest while preferring muskrat dens and cattails. Geographically weighted regression modeling predicted that these turtles would move towards preferred habitats and away from release sites with avoided non-preferred habitats. This research identified an estimated survival of between 63 and 96% over the eighteen month study period with all Blanding’s Turtles surviving their first winter in the refuge. This research suggests that headstarting programs for Blanding’s Turtles should… Advisors/Committee Members: Yoder-Nowak, Teresa (advisor), Dawson, Heather (committee member), Rybarczyk, Greg (committee member).

Subjects/Keywords: Blanding's turtle; geographic information system (GIS); habitat space use; headstarting; home range; thermoregulation; Wildlife conservation; Wildlife management; Ecology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Szymanski, M. (2016). Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI. (Masters Thesis). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/136883

Chicago Manual of Style (16^th Edition):

Szymanski, Melissa. “Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI.” 2016. Masters Thesis, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/136883.

MLA Handbook (7^th Edition):

Szymanski, Melissa. “Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI.” 2016. Web. 20 Apr 2021.

Vancouver:

Szymanski M. Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI. [Internet] [Masters thesis]. University of Michigan; 2016. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/136883.

Council of Science Editors:

Szymanski M. Investigation of Headstarted Blanding’s Turtles (Emydoidea blandingii) in Shiawassee National Wildlife Refuge, Saginaw, MI. [Masters Thesis]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/136883

University of Michigan

28. La Cruz, Nikita Latesha. Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains.

Degree: PhD, Earth and Environmental Sciences, 2019, University of Michigan

URL: http://hdl.handle.net/2027.42/153392

► Minerals are a key constituent of ore deposits that are the source of metals and non-metals required for our global society to function. In this… (more)

▼ Minerals are a key constituent of ore deposits that are the source of metals and non-metals required for our global society to function. In this dissertation, I use field and laboratory methods to understand the processes that lead to the formation of iron oxide - apatite deposits — an important source of iron — and as a tool for discovering new ore deposits. The analytical methods used include backscattered electron (BSE) imaging, cathodoluminescence (CL) imaging, and energy dispersive X-ray spectroscopy (EDS) element mapping, as well as electron probe micro-analysis (EPMA) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Chapter 2 describes an investigation of the chemistry of apatite from the Los Colorados iron - oxide apatite deposit, in Chile, that tested existing ore genesis hypotheses. My work indicates that apatite grains in the deposit contain distinct domains with chemistries that show statistically significant differences. The major, minor, and trace element chemistry of the apatite grains are consistent with growth from silicate melt and magmatic-hydrothermal fluid. The data are supportive of ore formation via magmatic/magmatic-hydrothermal fluids, according to a new model developed at the University of Michigan. In Chapter 3, I investigated the chemistry of magnetite and apatite from outcrop and drill core samples from five of the seven ore bodies at the El Laco iron - oxide apatite deposit, in Chile. Magnetite grains in the deepest samples have chemistries and textures consistent with growth of magnetite from a silicate melt, whereas the chemistries and textures of magnetite from the shallow samples and outcrops indicate growth of magnetite from magmatic-hydrothermal fluid. Apatite grains have major, minor, and trace element chemistry consistent with growth from a silicate melt or a magmatic-hydrothermal fluid. Magnetite and apatite grains contain mineral inclusions that preserve evidence for re-equilibration with hydrothermal fluids. Together, the data suggest that the ore bodies at El Laco formed via shallow emplacement and venting of magmatic-hydrothermal fluid suspensions that contained igneous magnetite microlites. In Chapter 4, I test the hypothesis that magnetite in stream sediment can be used as a tool for exploration in covered terrains, such as Guyana, located in the Guiana Shield. Similarities in the chemistries and textures of magnetite from outcrops and detrital grains in the same catchment indicate that the detrital grains can be used to gain insight about geological processes/sources in the catchments. However, the data also indicate changes in chemistry and loss of texture related to weathering and transport. Specifically, the concentrations of Mg, Ni, Cr, Ti, and Mn in magnetite are preserved in grains transported < 1.5 km in streams, whereas the concentrations of V and Al are preserved for transport distances up to 5 km. In order to test the hypothesis, I developed a new model that predicts the ore deposit sources of magnetite grains collected in… Advisors/Committee Members: Simon, Adam Charles (committee member), Oey, Sally (committee member), Kesler, Stephen E (committee member), Lange, Rebecca Ann (committee member), Wolf, Aaron Samuel (committee member).

Subjects/Keywords: Apatite Geochemistry; Magnetite Geochemistry; Iron oxide - apatite deposits; Mineral Exploration; Geochemical Discriminant Models; Guyana; Geology and Earth Sciences; Natural Resources and Environment; Statistics and Numeric Data; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

La Cruz, N. L. (2019). Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/153392

Chicago Manual of Style (16^th Edition):

La Cruz, Nikita Latesha. “Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains.” 2019. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/153392.

MLA Handbook (7^th Edition):

La Cruz, Nikita Latesha. “Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains.” 2019. Web. 20 Apr 2021.

Vancouver:

La Cruz NL. Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains. [Internet] [Doctoral dissertation]. University of Michigan; 2019. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/153392.

Council of Science Editors:

La Cruz NL. Using the Geochemistry of Magnetite and Apatite to Gain Insights Into the Genesis of Kiruna-type Ore Deposits and for Exploration in Densely Covered Terrains. [Doctoral Dissertation]. University of Michigan; 2019. Available from: http://hdl.handle.net/2027.42/153392

University of Michigan

29. Keerthi, Shamitha. Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2.

Degree: PhD, Natural Resources and Environment, 2017, University of Michigan

URL: http://hdl.handle.net/2027.42/137155

► The Renewable Fuels Standard (RFS2) under the Energy Independence and Security Act (EISA 2007) mandates the production of 36 billion gallons of biofuel by 2022… (more)

▼ The Renewable Fuels Standard (RFS2) under the Energy Independence and Security Act (EISA 2007) mandates the production of 36 billion gallons of biofuel by 2022 for use in the transportation sector. Although the mandate seeks to reduce greenhouse gas emissions by reducing our dependence on oil, there is concern that consequent land-use/cover (LULC) changes could result in significant unintended environmental impacts. The evaluation of water quality impacts from the mandate is challenging, especially for cellulosic and other advanced biofuels because the bioenergy supply chain is an emerging system with inherent uncertainties. This research addresses several gaps in the literature on the water quality impacts of the mandate and is organized into three chapters. The first chapter addresses the regional differences in impacts to water quality from a similar land-use change for two watersheds in the Midwest (Upper Cedar) and Southeast (Lumber). The Soil and Water Assessment Tool, a hydrological model that is able to simulate crop growth and water and nutrient outputs is set up, calibrated and validated. The potential reduction in nitrogen loading per potential gallon of ethanol to surface waters, for a change from baseline corn/soy to switchgrass, is about 40% in the Midwest and around 80% in the Southeast. Although, the trend in reduction is similar in both watersheds, this study shows that results extrapolated from the Midwest, where a lot of the bioenergy literature is based, may not be representative of other bioenergy producing regions. The second chapter investigates the impact of uncertainties in production costs of perennials on three objectives incentivizing different aspects of the biofuel industry – maximizing farmer profitability, surplus from feedstock production and ethanol production and land-use efficiency, using a Monte-Carlo Analysis. The study also investigates the impact of current farmer safety net for corn-soy production and bioenergy subsidies on the feedstock choice in each region. The analysis indicates that the three objectives result in different feedstock options in the two regions. Further, results indicate that the current incentive structure for perennial biomass is insufficient to encourage production on cropland, especially because the commodity crop alternative has better risk management. The final chapter of the dissertation links the feedstock production and ethanol production stages of the bioenergy supply chain. A Mixed Integer Linear Programming (MILP) optimization is used to drive land-use change at the Hydrologic Response Unit (HRU) level for the three objectives investigated in the second chapter. Results indicate there are tradeoffs between profitability and water quality for the three objectives. When the location of the biorefinery was considered, the supply of biomass and changes to water quality were localized around it, and these changes were significant at the sub-watershed scale. Optimization of biorefineries is usually done at the county or other large… Advisors/Committee Members: Miller, Shelie (committee member), Keoleian, Gregory A (committee member), Nassauer, Joan I (committee member), Xu, Ming (committee member).

Subjects/Keywords: Agricultural land-use change from Bioenergy; Water quality Impacts from the Bioenergy Mandate; Land-use tradeoff analysis; Regional water quality impacts from bioenergy; SWAT model for Bioenergy production; Natural Resources and Environment; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Keerthi, S. (2017). Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/137155

Chicago Manual of Style (16^th Edition):

Keerthi, Shamitha. “Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2.” 2017. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/137155.

MLA Handbook (7^th Edition):

Keerthi, Shamitha. “Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2.” 2017. Web. 20 Apr 2021.

Vancouver:

Keerthi S. Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/137155.

Council of Science Editors:

Keerthi S. Regional Differences in Water Quality Impacts from the Bioenergy Mandate: A Scenario-Based Approach to Quantifying the Impacts from RFS2. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/137155

University of Michigan

30. Sympson, Melanie Garcia. Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405.

Degree: PhD, History of Art, 2014, University of Michigan

URL: http://hdl.handle.net/2027.42/110492

► The Roman de la rose, by far the most popular romance in medieval Europe, was also one of the most richly and imaginatively illuminated works… (more)

▼ The Roman de la rose, by far the most popular romance in medieval Europe, was also one of the most richly and imaginatively illuminated works in French vernacular literature. Illuminators began providing miniatures in the late thirteenth century, focusing first on narrative episodes contained in the portion of the text composed by Guillaume de Lorris c. 1225-40, but increasingly coming to terms with Jean de Meun’s continuation, written about forty years later. In the course of more than two centuries of illumination, no single set of images emerged to accompany the narrative: pictorial cycles varied greatly in number of images, placement, and iconographic content. Over time, artists distinguished their copies from the work of predecessors by changing their manner of rendering and clothing the large cast of characters according to the latest fashions. Toward the end of the fourteenth century, when intellectuals in court circles began to debate the morality of Jean’s continuation, patrons became eager to own deluxe versions of a text that had by now become a classic. In this dissertation, I trace the nature and extent of these visual transformations over time by focusing on the production of Rose manuscripts in four shops active in Paris from c. 1338–c.1405. Richard and Jeanne de Montbaston (active c. 1338–1353), a husband and wife team, developed image cycles for at least seventeen manuscripts that exhibit the range of variation found in later copies of the text. Artist L of the Bible moralisée of John the Good (active c. 1350–65), working at a moment of market saturation, responded with image cycles that highlighted new fashions and more fully articulated the romance’s narrative. Four copies of the Rose illuminated by the Maître du Policratique de Charles V (active c. 1366–1403), and a singleton volume illuminated by an artist participating in a style known as the “Bedford Trend” (c. 1405–15), provide evidence that their artists collaborated with planners to create image cycles that reflected contemporary interests in the ethical and philosophical aspects of the text. Advisors/Committee Members: Sears, Elizabeth L. (committee member), McCracken, Peggy S. (committee member), Brusati, Celeste A. (committee member), Timmermann, Achim (committee member).

Subjects/Keywords: medieval illumination; Romance of the Rose (Roman de la rose); medieval manuscripts; Art History; Arts

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Sympson, M. G. (2014). Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/110492

Chicago Manual of Style (16^th Edition):

Sympson, Melanie Garcia. “Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405.” 2014. Doctoral Dissertation, University of Michigan. Accessed April 20, 2021. http://hdl.handle.net/2027.42/110492.

MLA Handbook (7^th Edition):

Sympson, Melanie Garcia. “Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405.” 2014. Web. 20 Apr 2021.

Vancouver:

Sympson MG. Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405. [Internet] [Doctoral dissertation]. University of Michigan; 2014. [cited 2021 Apr 20]. Available from: http://hdl.handle.net/2027.42/110492.

Council of Science Editors:

Sympson MG. Experiment and Visual Transformation in Illuminated Manuscripts of the Roman de la rose, c. 1338 – c. 1405. [Doctoral Dissertation]. University of Michigan; 2014. Available from: http://hdl.handle.net/2027.42/110492

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