publisher:("University of Bath")

University of Bath

1. Alhusein, Nour. Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs.

Degree: 2014, University of Bath

URL: http://opus.bath.ac.uk/41350/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629665

► Poly-ε-caprolactone (PCL), a semi-crystalline, linear polyester that is biocompatible and US Food and Drug Administration (FDA) approved, is investigated here in electrospinning research due to… (more)

▼ Poly-ε-caprolactone (PCL), a semi-crystalline, linear polyester that is biocompatible and US Food and Drug Administration (FDA) approved, is investigated here in electrospinning research due to its superior rheological and viscoelastic properties over other polymers. Tetracycline (Tet) was successfully incorporated and controlled release achieved from multilayered electrospun fibrous matrices consisting of PCL and poly(ethylene-co-vinyl acetate) (PEVA) with potential applications in wound healing. The formulation PCL/PEVA/PCL with Tet HCl in each layer gave a large initial (burst) release followed by a sustained release, to more than 15 days. There was no detectable loss of Tet chemical stability (as shown by NMR) or bioactivity (as shown by a modified Kirby–Bauer disc assay). Using Tet HCl sensitive bacteria, Staphylococcus aureus (ATCC 25923), the Tet HCl-loaded three-layered matrix formulations showed high antibacterial effects on days 4 and 5. Tet release was controlled from triple-layered electrospun matrices of zein or a zein/PCL blend, where the drug was loaded in the central layer with the outer two layers acting as diffusion barriers. Whilst untreated zein fibres are unstable in an aqueous environment, rapidly shrinking due to plasticization and film formation, blending zein with PCL stabilized the electrospun matrices and prevented them from shrinking. Death of a meticillin-resistant S. aureus strain MRSA252 was also demonstrated in a modified Kirby-Bauer disc assay over five days. Antibiotic nafcillin sodium was co-electrospun with PCL to investigate the incorporation and controlled release of nafcillin from PCL electrospun fibres, but results showed nafcillin degradation over time. Controlled release of siRNA from PCL electrospun fibres was also investigated. siRNA nanoparticle adsorption on the surface of PCL electrospun fibres did not lead to sustained release of siRNA. The antibacterial effects of Tet encapsulated fibrous matrices were further investigated against S. aureus MRSA252 biofilms. Results showed high biological activity in increasingly complex models of biofilm formation (models that are closer to the situation in a wound) by stopping biofilm formation, by killing preformed biofilms, and by killing mature, dense biofilm colonies of S. aureus MRSA252.

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APA (6^th Edition):

Alhusein, N. (2014). Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/41350/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629665

Chicago Manual of Style (16^th Edition):

Alhusein, Nour. “Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs.” 2014. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/41350/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629665.

MLA Handbook (7^th Edition):

Alhusein, Nour. “Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs.” 2014. Web. 17 Feb 2019.

Vancouver:

Alhusein N. Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs. [Internet] [Doctoral dissertation]. University of Bath; 2014. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/41350/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629665.

Council of Science Editors:

Alhusein N. Polymeric delivery systems : electrospun nanofibre layers for controlled delivery of drugs. [Doctoral Dissertation]. University of Bath; 2014. Available from: http://opus.bath.ac.uk/41350/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629665

University of Bath

2. Walsh, Emily Jane. Moving mesh methods for problems in meteorology.

Degree: 2010, University of Bath

URL: http://eprints.uwe.ac.uk/23629/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538285

► This thesis considers the development and implementation of a moving mesh strategy which is suitable for the numerical solution of partial differential equations (PDEs) that… (more)

▼ This thesis considers the development and implementation of a moving mesh strategy which is suitable for the numerical solution of partial differential equations (PDEs) that arise in problems relevant to meteorology. We concentrate primarliy on developing the Parabolic Monge-Ampère (PMA) moving mesh method. This is an r-adaptive method which is based on ideas from optimal transportation combined with the equidistribution principle applied to a (time varying) scalar monitor function (used successfully in moving mesh methods in one-dimension). The mesh is obtained by taking the gradient of a (scalar) mesh potential function which satisfies an appropriate nonlinear parabolic partial differential equation. This method is straightforward to program and implement, requiring the solution of only one simple scalar time-dependent equation in arbitrary dimension. Furthermore it produces meshes of provable regularity and smoothness. The mesh equation is augmented with suitable Neumann or periodic boundary conditions, with adaptivity along the boundaries handled automatically. Examples are presented of periodic and non-periodic meshes generated for a prescribed monitor function. The PMA mesh equation is then successfully coupled to a number of convection dominated PDEs in 1D and 2D and the relative merits of solving the resultant systems, using a simultaneous or an alternate solution procedure, are explored. The main test problem considered is the two-dimensional Eady problem, a meteorological problem which models the development of cyclones at mid-latitudes. Numerical solutions obtained on an adaptive grid using PMA are presented. The results show improved resolution of the front when compared to uniform grid solutions with an equivalent number of mesh points and computed with the same time step. A pressure-correction method is implemented on a semi-staggered adaptive grid that also conserves important physical properties of the solution. All numerical solutions presented involve discretising the underlying equations in the computational domain, which is fixed and uniform, using a finite difference scheme. An alternating strategy is implemented whereby the Eady equations are integrated first and then the mesh is updated. A conservative interpolation scheme is used to interpolate the updated solution from the old grid onto the new grid.

Subjects/Keywords: 518

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APA (6^th Edition):

Walsh, E. J. (2010). Moving mesh methods for problems in meteorology. (Doctoral Dissertation). University of Bath. Retrieved from http://eprints.uwe.ac.uk/23629/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538285

Chicago Manual of Style (16^th Edition):

Walsh, Emily Jane. “Moving mesh methods for problems in meteorology.” 2010. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://eprints.uwe.ac.uk/23629/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538285.

MLA Handbook (7^th Edition):

Walsh, Emily Jane. “Moving mesh methods for problems in meteorology.” 2010. Web. 17 Feb 2019.

Vancouver:

Walsh EJ. Moving mesh methods for problems in meteorology. [Internet] [Doctoral dissertation]. University of Bath; 2010. [cited 2019 Feb 17]. Available from: http://eprints.uwe.ac.uk/23629/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538285.

Council of Science Editors:

Walsh EJ. Moving mesh methods for problems in meteorology. [Doctoral Dissertation]. University of Bath; 2010. Available from: http://eprints.uwe.ac.uk/23629/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538285

University of Bath

3. Al-Qenaei, Abdullah. The role of iron in rheumatoid arthritis.

Degree: 2008, University of Bath

URL: http://opus.bath.ac.uk/12866/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492287

► Iron plays a potential role in oxidative stress-mediated injuries and pathologies e.g. rheumatoid arthritis (RA). Four decades ago it was suggested that iron may have… (more)

▼ Iron plays a potential role in oxidative stress-mediated injuries and pathologies e.g. rheumatoid arthritis (RA). Four decades ago it was suggested that iron may have a crucial role in the progression of inflammation in RA. Indeed, free radicals generated by iron can cause damage to lipids, proteins, carbohydrates, and DNA. It is this destructive process that is believed to occur in rheumatoid joints. However, none had differentiated between the role of iron in both acute and chronic phases of the disease and the origin of this 'labile' iron. Since RA cells are chronically exposed to oxidative stress, we have therefore chosen Jurkat cells to be our cell model. We used the parental (J16) cell line was used to mimic the acute phase of oxidative stress and the H2O2-resistant (HJ16) cells to mimic the chronic phase. By using hydrogen peroxide (H2O2) as the oxidising agent, we aim to study the role of iron in acute and chronic phase of oxidative stress and to know its origin. In the present study, we found that both antioxidants and H2O2-induced labile iron are modulated when cells are chronically exposed to H2O2. HJ16 cells contain higher total intracellular glutathione levels and glutathione peroxidase activity than J16 cells while the superoxide dismutase and catalase activity are similar. Haem oxygenase-1 (HO-1) was not detectable nor was it induced in these cell lines; HO-2 on the other hand was expressed but not induced. Although they had the same ‘basal’ LIP and L-Ft levels, J16 cells contain more than 7-fold higher H-Ft levels than in HJ16 cells. It was also found that H2O2-induced labile iron is directly correlated with necrotic cell death. These results are consistent with the conclusion that both antioxidant defence mechanism and labile iron status are modulated in cells chronically exposed to H2O2. We have also shown that the ‘basal’ and ‘H2O2-induced’ NFκB activation was higher in the HJ16 cells. We have also provided a link between labile iron release, lysosomal membrane damage and the ensuing necrotic cell death following H2O2 treatment.

Subjects/Keywords: 615.1

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APA (6^th Edition):

Al-Qenaei, A. (2008). The role of iron in rheumatoid arthritis. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/12866/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492287

Chicago Manual of Style (16^th Edition):

Al-Qenaei, Abdullah. “The role of iron in rheumatoid arthritis.” 2008. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/12866/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492287.

MLA Handbook (7^th Edition):

Al-Qenaei, Abdullah. “The role of iron in rheumatoid arthritis.” 2008. Web. 17 Feb 2019.

Vancouver:

Al-Qenaei A. The role of iron in rheumatoid arthritis. [Internet] [Doctoral dissertation]. University of Bath; 2008. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/12866/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492287.

Council of Science Editors:

Al-Qenaei A. The role of iron in rheumatoid arthritis. [Doctoral Dissertation]. University of Bath; 2008. Available from: http://opus.bath.ac.uk/12866/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492287

University of Bath

4. Guillén Marín, Clara. The representation of migrants in contemporary Spanish cinema.

Degree: PhD, 2015, University of Bath

URL: http://opus.bath.ac.uk/47054/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665442

► This study will focus on the analysis of eight films representing migrants in Spain. The films are documentaries and fiction films made by Spanish and… (more)

Subjects/Keywords: 791.43

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APA (6^th Edition):

Guillén Marín, C. (2015). The representation of migrants in contemporary Spanish cinema. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/47054/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665442

Chicago Manual of Style (16^th Edition):

Guillén Marín, Clara. “The representation of migrants in contemporary Spanish cinema.” 2015. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/47054/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665442.

MLA Handbook (7^th Edition):

Guillén Marín, Clara. “The representation of migrants in contemporary Spanish cinema.” 2015. Web. 17 Feb 2019.

Vancouver:

Guillén Marín C. The representation of migrants in contemporary Spanish cinema. [Internet] [Doctoral dissertation]. University of Bath; 2015. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/47054/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665442.

Council of Science Editors:

Guillén Marín C. The representation of migrants in contemporary Spanish cinema. [Doctoral Dissertation]. University of Bath; 2015. Available from: http://opus.bath.ac.uk/47054/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665442

University of Bath

5. Abdullah, Sabah. Willingness to pay for renewable energy options in developing countries : the case of Kenya.

Degree: PhD, 2009, University of Bath

URL: http://opus.bath.ac.uk/18617/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503705

► Modern energy services such as electricity offer social, economic and health benefits, particularly for rural households who depend wholly and solely on traditional fuels. However,… (more)

▼ Modern energy services such as electricity offer social, economic and health benefits, particularly for rural households who depend wholly and solely on traditional fuels. However, one of the impediments faced by rural households in connecting to these services is the high cost of connection. Once a household is electrified by the grid, another problem emerges which is service reliability from the grid-option. Some examples of such reliability problems are: high frequency of outages and their substantial duration. Hence, it is important to consider both the connection costs for nonelectrified households and service reliability for those who are already electrified. In this vein, this research aims to explore the most efficient pathways to achieve higher levels of electricity connection and greater reliability, focusing on rural households in Kenya. To achieve this, a face-to-face household survey consisting of 200 nonelectrified and 202 electrified households was conducted in Kisumu district in August 2007. Two hypothetical stated preference methods are employed, these being a contingent valuation approach for nonelectrified households and a choice experiment for electrified households. The empirical model used for the contingent valuation includes a double bounded logit, whereas for choice experiment a mixed logit is applied. In the case of contingent valuation, the double bounded logit is preferable due to the double bounded question format used in the household survey. For the choice experiment, the mixed logit is applied owing to the preference heterogeneity which was found among respondents with regards to the reliability of electricity services. The results from the double bounded logit model revealed that among nonelectrified households the willingness to pay for two electricity sources, namely grid and photovoltaic systems, differed. Respondents were willing to pay more for grid electricity than a solar photovoltaic system. Moreover, those who were older and had lived longer in the area were less inclined to pay for electricity connection, whereas those who had higher incomes and those interested in using electricity for home business purposes, were found to be more in favour of connection to electricity services than those exhibiting the converse xi characteristics. Question order effect was also investigated for the contingent valuation method, and it emerged that the overall mean/median willingness to pay was unaffected by the product and payment effects. In addition, monthly payments were found to be more popular than lump sum for connection. The mixed logit estimation for choice experiment provided insights into respondents’ heterogeneity with regards to the socio-economic and demographic variables. It emerged that those who were: unemployed, older and lived longer in the area, were less likely than their counterparts to pay in excess of their monthly electricity bill to reduce outages. Moreover, those who had a larger family, were engaged in farming and/or had a bank account were willing to pay more for…

Subjects/Keywords: 333

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Abdullah, S. (2009). Willingness to pay for renewable energy options in developing countries : the case of Kenya. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/18617/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503705

Chicago Manual of Style (16^th Edition):

Abdullah, Sabah. “Willingness to pay for renewable energy options in developing countries : the case of Kenya.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/18617/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503705.

MLA Handbook (7^th Edition):

Abdullah, Sabah. “Willingness to pay for renewable energy options in developing countries : the case of Kenya.” 2009. Web. 17 Feb 2019.

Vancouver:

Abdullah S. Willingness to pay for renewable energy options in developing countries : the case of Kenya. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/18617/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503705.

Council of Science Editors:

Abdullah S. Willingness to pay for renewable energy options in developing countries : the case of Kenya. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/18617/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503705

University of Bath

6. Ferrero, Juan Pablo. The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil.

Degree: PhD, 2012, University of Bath

URL: http://opus.bath.ac.uk/34851/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569759

► The Transition School helped to understand interactions between elites and popular mobilisation both favouring and conditioning the establishment of democratic rule in Latin America. As… (more)

▼ The Transition School helped to understand interactions between elites and popular mobilisation both favouring and conditioning the establishment of democratic rule in Latin America. As the reestablishment of authoritarian regimes became no longer a serious risk, the debate shifted towards ideas of ‘regime consolidation’ and the ‘quality of democracy’ highlighting the importance of (consolidated or better) political institutions as primary locus to achieve it. As a consequence, the study of social movement organisations and trade unions remained to a large extent disconnected to the quest for democratisation. In order to advance the latter I engage with Radical Democracy as it provides new elements to unravel processes of deepening democracy, i.e., to reconnects the quest for democracy with egalitarian struggles upon the contingent structuration of antagonistic conflict. My argument is that the politics of democratisation in post-transition contexts concerns the formation of democratic subjectivities as the production of transformative action and the expansion of equality. More specifically, I suggest that in the context of Argentina and Brazil, the formation of democratic subjectivities was the result of three overlapping though differentiable ‘internal’ dynamics in relation to the institution of two ‘external’ temporal limits. The relationship between the former (self-organising, networking and demanding) and the latter (‘anti-neoliberalism’ and ‘beyond-governments’) explains the displacement from ‘disagreement’ to ‘participation’ resonating both socio-political conflict and its effects on change and continuity in the politics of post-transition (1990s - 2000s). Methodologically, I explore the discourse and practice of a qualitatively significant number case studies constructed upon trade unions (Central de Trabajadores Argentinos and Central Única dos Trabalhadores) and social movement organisations (Federación de Tierra, Vivienda y Hábitat and Movimento dos Trabalhadores Rurais Sem Terra) and, only indirectly, political parties and other political institutions. Their clear involvement in political mobilisation though less clear engagement on electoral politics justifies the exploration of the democracy question on new sources under a qualitative perspective. The argument is organised in three parts and seven chapters. I firstly discuss Radical Democracy in relation to alternative interpretations and also present the reasons for the selection of case studies. The second part explains the formation of democratic subjectivities in Argentina and Brazil by drawing on the analysis of first and secondary data. Thirdly, I narrate the ‘politics of democratisation’ in post-transition contexts based exclusively on research findings. Finally, I critically reassess Radical Democracy which has been heavily theorised but insufficiently empirically scrutinised. I aim to fill this gap as well as to further the understanding on the formation of disagreement, where the drivers for further democratisation lie in ongoing contention.

Subjects/Keywords: 320.48

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Ferrero, J. P. (2012). The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/34851/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569759

Chicago Manual of Style (16^th Edition):

Ferrero, Juan Pablo. “The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil.” 2012. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/34851/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569759.

MLA Handbook (7^th Edition):

Ferrero, Juan Pablo. “The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil.” 2012. Web. 17 Feb 2019.

Vancouver:

Ferrero JP. The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil. [Internet] [Doctoral dissertation]. University of Bath; 2012. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/34851/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569759.

Council of Science Editors:

Ferrero JP. The politics of democratisation in post-transition contexts : social movement organisations and trade unions in the production of democratic subjectivities in Argentina and Brazil. [Doctoral Dissertation]. University of Bath; 2012. Available from: http://opus.bath.ac.uk/34851/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569759

University of Bath

7. Gesell, Anne E. Investigating the role of Yes-associated protein (YAP) in neural crest development.

Degree: phd, 2014, University of Bath

URL: http://opus.bath.ac.uk/49307/

► The neural crest (NC) is a multipotent embryonic cell type derived from the ectoderm during neurulation giving rise to a variety of cell lineages such… (more)

▼ The neural crest (NC) is a multipotent embryonic cell type derived from the ectoderm during neurulation giving rise to a variety of cell lineages such as neurons, glia and pigment cells. Most genes associated with the correct initiation, differentiation and migration of the neural crest have been found through reverse genetics. Similarities between neural crest development and some features of cancer progression are remarkable. For instance, it has been suggested that some cancer types recapitulate NC processes in an unregulated manner such as epithelial-mesenchymal transition or active cell migration throughout the body to form distant metastases. However, to date very little is known about initiators and drivers that direct neural crest cell migration to specific target sites. The Medaka mutant hirame represents an interesting melanocyte specific migration defect on the yolk sac caused by a loss of functional Yes-associated protein (YAP). Medaka hirame mutants were initially studied for their profound changes in body morphology. Genomic mapping identified the causal mutation as a nonsense point mutation within the first WW domain in the Yes-associated protein 1 (YAP1), causing translation of a dysfunctional YAP protein. YAP is a downstream transcriptional co-activator of the recently discovered and evolutionarily conserved Hippo pathway. Alterations within Hippo signalling are linked to cell survival, proliferation and abnormal tissue overgrowth. We demonstrate that hirame melanocyte precursors (melanoblasts) are initially present in normal abundance, but show an early migration defect with a lack of melanoblasts on the yolk sac, and corresponding accumulation in the lateral parts of the body. Subsequently, we observe an overall decline in differentiated melanocyte numbers during late stage embryogenesis. We designed an overexpression cassette linking enhanced GFP to either wild type or a mutated activated version of YAP and present evidence that it can efficiently rescue the melanocyte defect after injection of mRNA into one-cell stage embryos. Furthermore, analysis of the yolk sac anatomy via transmission electron microscopy indicates that a fraction of yolk membrane cells undergo apoptosis and we propose that this may contribute to the establishment of altered environmental cues leading to abnormal melanoblast migration onto the yolk sac. Injection of yap mRNA directly into the yolk sac however, failed to rescue melanoblast patterning. To advance our study, we isolated and characterised a 3.6 kb Medaka dopachrome tautomerase (Dct) promoter fragment, and used it to drive expression of enhanced green fluorescent protein (eGFP) in vivo. We generated germline transgenics with this construct that showed lineage-specific expression of eGFP within early migrating melanoblasts, a phenotype that is maintained in differentiated melanocytes throughout embryogenesis. In addition, using this promoter we overexpressed our egfp-yap fusion cassette and established transgenic lines to assess the cell autonomy of YAP within the…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gesell, A. E. (2014). Investigating the role of Yes-associated protein (YAP) in neural crest development. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/49307/

Chicago Manual of Style (16^th Edition):

Gesell, Anne E. “Investigating the role of Yes-associated protein (YAP) in neural crest development.” 2014. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/49307/.

MLA Handbook (7^th Edition):

Gesell, Anne E. “Investigating the role of Yes-associated protein (YAP) in neural crest development.” 2014. Web. 17 Feb 2019.

Vancouver:

Gesell AE. Investigating the role of Yes-associated protein (YAP) in neural crest development. [Internet] [Doctoral dissertation]. University of Bath; 2014. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/49307/.

Council of Science Editors:

Gesell AE. Investigating the role of Yes-associated protein (YAP) in neural crest development. [Doctoral Dissertation]. University of Bath; 2014. Available from: http://opus.bath.ac.uk/49307/

University of Bath

8. Grieve, Tigist. Seeing the Social:Understanding why children are out of school in rural Ethiopia.

Degree: phd, 2016, University of Bath

URL: http://opus.bath.ac.uk/51011/

► The promotion of education has long been a priority of the successive regimes of Ethiopia. Combined with the momentum of Education for All (EFA) and… (more)

▼ The promotion of education has long been a priority of the successive regimes of Ethiopia. Combined with the momentum of Education for All (EFA) and the Millennium Development Goals (MDGs) in recent years Ethiopia’s education sector has experienced a major expansion of primary school enrolment which has earned Ethiopia international acclaim and so much optimism in meeting the MDGs set for 2015. Despite this, however, large numbers of primary school aged children remain out of school, most of these are found in rural areas and many of them are girls. Many of the children that enrol do not stay on to complete the full cycle of their primary schooling. While there are numerous studies looking at rural children’s schooling, village-based ethnographic studies are rare, particularly in Ethiopia. The thesis offers a sociological insight as to why low enrolment and incompletion persist in rural areas. Drawing on an ethnographic approach study over extended period this thesis presents analysis of data from two local communities. Methodologically the analysis are anchored on the voices of the children, their parents and teachers and make a valuable contribution in emphasising not only the importance of bringing local people’s own voices into the debate, but also drawing attention to the ways voice may be utilised and calling for greater sensitivity to the way it is interpreted in scholarly and policy circles. Theoretically, the study shows the value of applying Bourdieu’s approach to social reproduction in analysing the challenges faced by rural children in completing primary school. Time spent with children, their families and their teachers suggests reproduction of educational inequality at all levels (home, school, community). While these are certainly important, this thesis argues that more attention needs to be paid to the social context in which children and their schooling are embedded. It suggests the challenges in schooling rural children are not simply explained either by the quantity of primary schools available, or a lack of value being accorded to education, or deliberate acts of discrimination (e.g. against girls). Rather, it has argued that discriminatory outcomes, or the reproduction of social inequality, have to be understood as the outcome of social practice, where ‘choices’ are made in circumstances of considerable constraint. Furthermore, it has shown that these patterns of social reproduction are as characteristic of teachers and the field of the school as they are of parents and children and the field of home and community. Rather than the school operating as an external change agent, as imagined in much of the education literature, the school is very much part of the local social context. The application of policies and the social practice of staff are significantly marked by their positionality within the communities which they serve.

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APA (6^th Edition):

Grieve, T. (2016). Seeing the Social:Understanding why children are out of school in rural Ethiopia. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/51011/

Chicago Manual of Style (16^th Edition):

Grieve, Tigist. “Seeing the Social:Understanding why children are out of school in rural Ethiopia.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/51011/.

MLA Handbook (7^th Edition):

Grieve, Tigist. “Seeing the Social:Understanding why children are out of school in rural Ethiopia.” 2016. Web. 17 Feb 2019.

Vancouver:

Grieve T. Seeing the Social:Understanding why children are out of school in rural Ethiopia. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/51011/.

Council of Science Editors:

Grieve T. Seeing the Social:Understanding why children are out of school in rural Ethiopia. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/51011/

University of Bath

9. Jamshidi, Akbar. Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME.

Degree: 2016, University of Bath

URL: http://opus.bath.ac.uk/56430/

► This thesis examines the implementation of an improved manufacturing information system for production engineering that was carried out over a period of 30 months within… (more)

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APA (6^th Edition):

Jamshidi, A. (2016). Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME. (Thesis). University of Bath. Retrieved from http://opus.bath.ac.uk/56430/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Jamshidi, Akbar. “Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME.” 2016. Thesis, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/56430/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Jamshidi, Akbar. “Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME.” 2016. Web. 17 Feb 2019.

Vancouver:

Jamshidi A. Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME. [Internet] [Thesis]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/56430/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Jamshidi A. Improved Manufacturing Processes for Machining of Hard Metal Alloys in an SME. [Thesis]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/56430/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Bath

10. Gregory, Georgina. Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications.

Degree: phd, 2017, University of Bath

URL: http://opus.bath.ac.uk/56713/

► The biodegradability and when functionalised biocompatibility of aliphatic polycarbonates (APCs) makes them an attractive class of materials for biomedical applications such as tissue engineering scaffolds… (more)

▼ The biodegradability and when functionalised biocompatibility of aliphatic polycarbonates (APCs) makes them an attractive class of materials for biomedical applications such as tissue engineering scaffolds and drug-delivery carriers. One route to accessing a wide-range of well-defined and functional APCs is the controlled ring-opening polymerisation (ROP) of cyclic carbonates. In turn, these would ideally be prepared by the direct coupling of CO2 with diols to give water as the only by-product. In this way, the combination of CO2 and sugar-derived diols draws upon two natural renewable building blocks for the construction of polycarbonates that are anticipated to show good biocompatibility properties. Chapter 2 develops a simple and mild alternative to the traditional use of phosgene derivatives for the synthesis of six-membered cyclic carbonates from 1,3-diols and CO2. DFT calculations highlighted the need to lower both the CO2-insertion and ring-closing kinetic barriers to cyclic carbonate formation. Organic superbase, 1,8- diazabicyclo[5.4.0]undec-7-ene (DBU) enabled the formation of carbonate species at 1 atm CO2 pressure whereas, the introduction of a leaving group strategy lowered the cyclisation barrier. Mechanistic considerations suggested a kinetic preference for ring- closing via a nucleophilic addition-elimination pathway rather than a SN2-like intramolecular cyclisation. Chapter 3 applies the procedure with CO2 to the preparation of a novel monomer from natural sugar, ᴅ-mannose. ROP was carried out via an organocatalytic approach and a preference for head-tail linkages in the polycarbonate backbone indicated by NMR spectroscopy and supported by DFT calculations. Chapter 4 utilises CO2 to invert the natural stereochemistry of sugars and create a thymidine-based monomer. The thermodynamic parameters of the ROP with 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) catalyst are determined and the properties of the polycarbonates investigated to include preliminary cell attachment studies. Finally, chapter 5 details the synthesis of cyclic carbonates from 2- deoxy-ᴅ-ribose and the investigation into the different ROP behaviour of the α- and β- anomers. The ability to tune the polymer properties through copolymerisation with trimethylene carbonate (TMC) is also discussed.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gregory, G. (2017). Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/56713/

Chicago Manual of Style (16^th Edition):

Gregory, Georgina. “Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications.” 2017. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/56713/.

MLA Handbook (7^th Edition):

Gregory, Georgina. “Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications.” 2017. Web. 17 Feb 2019.

Vancouver:

Gregory G. Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications. [Internet] [Doctoral dissertation]. University of Bath; 2017. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/56713/.

Council of Science Editors:

Gregory G. Cyclic Carbonates from Sugars and Carbon Dioxide: Synthesis, Polymerisation and Biomedical Applications. [Doctoral Dissertation]. University of Bath; 2017. Available from: http://opus.bath.ac.uk/56713/

University of Bath

11. Enang, Wisdom. Robust real-time control of a parallel hybrid electric vehicle.

Degree: phd, 2016, University of Bath

URL: http://opus.bath.ac.uk/56714/

► The gradual decline in global oil reserves and the presence of ever so stringent emissions rules around the world have created an urgent need for… (more)

▼ The gradual decline in global oil reserves and the presence of ever so stringent emissions rules around the world have created an urgent need for the production of automobiles with improved fuel economy. HEVs (hybrid electric vehicles) have proved a viable option to guaranteeing improved fuel economy and reduced emissions. The fuel consumption benefits which can be realised when utilising HEV architecture are dependent on how much braking energy is regenerated, and how well the regenerated energy is utilised. The challenge in developing a real-time HEV control strategy lies in the satisfaction of often conflicting control constraints involving fuel consumption, emissions and driveability without over-depleting the battery state of charge at the end of the defined driving cycle. Reviewed literature indicates some research gaps and hence exploitable study areas for which this thesis intends to address. For example, despite the research advances made, HEV energy management is still lacking in several key areas: optimisation of braking energy regeneration; real-time sub-optimal control of HEV for robustness, charge sustenance and fuel reduction; and real-time vehicle speed control. Consequently, this thesis aims to primarily develop novel real-time near-optimal control strategies for a parallel HEV, with a view to achieving robustness, fuel savings and charge sustenance simultaneously, under various levels of obtainable driving information (no route preview information, partial route preview information). Using a validated HEV dynamic simulation model, the following novel formulations are proposed in this thesis and subsequently evaluated in real time: 1. A simple grouping system useful for classifying standard and real-world driving cycles on the basis of aggressivity and road type. 2. A simple and effective near-optimal heuristic control strategy with no access to route preview information. 3. A dynamic programming-inspired real-time near-optimal control strategy with no access to route preview information. 4. An ECMS (Equivalent Consumption Minimisation Strategy) inspired real-time near-optimal control strategy with no access to route preview information. 5. An ECMS-inspired real-time near-optimal control strategy with partial access to route preview information. 6. A dynamic programming based route-optimal vehicle speed control strategy which accounts for real-time dynamic effects like engine braking, while solving an optimisation problem involving the maximisation of fuel savings with little or no penalty to trip time. 7. A real-time vehicle speed control approach, which is based on smoothing the speed trajectory of the lead vehicle, consequently reducing the acceleration and deceleration events that the intelligent vehicle (follower vehicle) will undergo. This smoothing effect translates into reduced fuel consumption, which tends to increase with increasing traffic preview window. Among other studies performed in this thesis, the fuel savings potential of the proposed near-optimal controllers was investigated in…

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APA (6^th Edition):

Enang, W. (2016). Robust real-time control of a parallel hybrid electric vehicle. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/56714/

Chicago Manual of Style (16^th Edition):

Enang, Wisdom. “Robust real-time control of a parallel hybrid electric vehicle.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/56714/.

MLA Handbook (7^th Edition):

Enang, Wisdom. “Robust real-time control of a parallel hybrid electric vehicle.” 2016. Web. 17 Feb 2019.

Vancouver:

Enang W. Robust real-time control of a parallel hybrid electric vehicle. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/56714/.

Council of Science Editors:

Enang W. Robust real-time control of a parallel hybrid electric vehicle. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/56714/

University of Bath

12. Douglas, Josephine Marie. The importance of hydrodynamics and mechanical action in fabric washing.

Degree: phd, 2017, University of Bath

URL: http://opus.bath.ac.uk/56715/

► Washing fabrics is a ubiquitous process that has been found to have been common even in early civilisations. The process can be performed by hand… (more)

▼ Washing fabrics is a ubiquitous process that has been found to have been common even in early civilisations. The process can be performed by hand or with the aid of a washing machine, giving rise to a wide range of wash conditions. Although this process is very common the mechanisms involved are poorly understood, but are thought to involve chemical, mechanical and hydrodynamic inputs. The main aim of this project is to test whether these inputs can be used to improve the efficiency of cleaning fabrics at lower temperatures, and to better understand the mechanisms involved in these individual actions. The cleaning of polyester and cotton fabrics soiled with artificial sebum has been investigated with 20 °C, 40 °C and 60 °C wash solutions. Fabrics have been cleaned with a model surfactant system consisting of Linear Alkylbenzene Sulfonate (LAS) at 0.1 times and twice the Critical Micelle Concentration (CMC), and results compared to water. Bespoke rigs to simulate rubbing, stretching and flow have been optimised and methods developed for cleaning and analysis of fabrics. Cleaning has been characterised by mass change, colour change and resistance change. Mass change gives an indication of the overall removal, whereas colour gives an analytical measure of the difference in the appearance of the fabrics, and change in resistance to flow of water through the fabric shows how much sebum has been removed from the pores. Additional analysis has been completed on the fabrics including FTIR, mass per unit area, SEM and zeta potential measurements. Removal was highest when the fabric was washed at 60 °C with a high concentration of surfactant. Soaking alone removed some of the mass, but this increased when mechanical action was also used. Of the mechanical actions, rubbing was found to be the most effective under most conditions. On the whole, cleaning was more effective at 40 °C than 20 °C, and a higher concentration of surfactant aided removal of soil to a greater extent that at a lower concentration or with water alone. However, some exceptions to these trends have been identified.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Douglas, J. M. (2017). The importance of hydrodynamics and mechanical action in fabric washing. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/56715/

Chicago Manual of Style (16^th Edition):

Douglas, Josephine Marie. “The importance of hydrodynamics and mechanical action in fabric washing.” 2017. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/56715/.

MLA Handbook (7^th Edition):

Douglas, Josephine Marie. “The importance of hydrodynamics and mechanical action in fabric washing.” 2017. Web. 17 Feb 2019.

Vancouver:

Douglas JM. The importance of hydrodynamics and mechanical action in fabric washing. [Internet] [Doctoral dissertation]. University of Bath; 2017. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/56715/.

Council of Science Editors:

Douglas JM. The importance of hydrodynamics and mechanical action in fabric washing. [Doctoral Dissertation]. University of Bath; 2017. Available from: http://opus.bath.ac.uk/56715/

University of Bath

13. Thake, Anne Marie. A critical review of graduate employability skills : lessons from the Maltese experience.

Degree: phd, 2016, University of Bath

URL: http://opus.bath.ac.uk/56716/

► This study examines how institutional actors interpret, influence and respond to skills availability in the labour market for graduates. It researches and draws lessons from… (more)

▼ This study examines how institutional actors interpret, influence and respond to skills availability in the labour market for graduates. It researches and draws lessons from the Maltese experience of managing graduate employability over three decades, focusing on the three fastest-growing economic sectors, namely, Accountancy, Pharmachem and ICT, each of which is the subject of a case study. The study investigates the interaction of governments, firms, higher education institutions and professional associations in identifying skills shortages and gaps, as well as in devising policy frameworks and skills regimes at national, sectoral and corporate levels. Drawing upon theories of employability and employee skills, first, there is development of an analytical framework to examine how these institutional actors affect the labour market, which informs the analysis of the three case studies. The qualitative research involved an interpretative analysis of key policy documents related to graduate employability and seventy in-depth interviews with interlocutors positioned in strategic policy making, senior management, academic, expert and professional leadership roles within government, regulators, major corporations, higher education institutions, training providers and professional associations. The data was thematically analysed. Twelve key themes emerged from the in-depth interviews, which included the following: use of different language; the meaning of employability; the value of credentials; the role of the University; perceptions; expectations; competitiveness; modes of training provision; labour mobility; placements and incentives; collaboration and skills gap. The institutional actors across the three focal sectors, namely, accountancy, pharmachem and ICT tended to emphasise some themes more than others, these having previously been identified in scholarly literature (Appendix 1). Both patterns and inconsistencies emerged from a comparison of the accountancy, pharmachem and ICT sectors. In so far as the labour market is concerned, the study revealed a lack of technical skills and major non-technical graduate skills gaps, specifically, in the aspects of communication, teamwork and problem-solving. A number of professional characteristics or behaviours were also identified as lacking with Accountancy, Pharmachem and ICT graduates, namely, attitude, confidence, drive, professional outlook, independent working, personality fit and a ‘can do’ approach. The study revealed the absence of permanent systemic connections between the formulation of national and sectoral economic strategies on the one hand, and higher education and training policies on the other. Consequently, state higher education institutions have been responding reactively to labour market needs, which could explain the endemic skills gap which the study found. The study concludes by discussing limitations and limits to this research as well as recommending policy initiatives and further research that could contribute to the science and practice of public…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Thake, A. M. (2016). A critical review of graduate employability skills : lessons from the Maltese experience. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/56716/

Chicago Manual of Style (16^th Edition):

Thake, Anne Marie. “A critical review of graduate employability skills : lessons from the Maltese experience.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/56716/.

MLA Handbook (7^th Edition):

Thake, Anne Marie. “A critical review of graduate employability skills : lessons from the Maltese experience.” 2016. Web. 17 Feb 2019.

Vancouver:

Thake AM. A critical review of graduate employability skills : lessons from the Maltese experience. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/56716/.

Council of Science Editors:

Thake AM. A critical review of graduate employability skills : lessons from the Maltese experience. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/56716/

University of Bath

14. Papacharalampou, Chrysoula. Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach.

Degree: phd, 2017, University of Bath

URL: http://opus.bath.ac.uk/57357/

► In the water utility sector, traditional asset management focusses on the maintenance and provision of physical assets (infrastructure) that allow water companies to deliver their… (more)

▼ In the water utility sector, traditional asset management focusses on the maintenance and provision of physical assets (infrastructure) that allow water companies to deliver their services, meet their customers’ expectations and achieve their economic objectives. Nevertheless, the serviceability of the sector heavily depends on natural elements (e.g. rain, land). The importance of Natural Capital (i.e. the natural systems and their deriving ecosystem services) has been at the core of policy recommendations which have shaped regulatory changes in the water sector of England and Wales. Water companies are now required to explicitly account for and report their inter-dependencies on the natural environment and adopt systems-oriented approaches in their Asset Management Programmes (AMPs). These reforms will enable the sector to become resilient to the environmental and societal challenges faced at urban and rural contexts. Responding to the regulatory demands, the research introduces a novel and structured approach for integrating natural capital in the asset management portfolio of the water industry. The work is built on a transdisciplinary research framework and demonstrates that a new scale needs to be considered for the implementation of Holistic Asset Management: the water basin or catchment. A Catchment Metabolism modelling schema was created, grounded on the principles of Integrated Catchment Management and ecosystems services. The schema is based on the robust synthesis of concepts, tools and methods from a spectrum of disciplines. These include Industrial Ecology, Water Accounting, Environmental Regional Input-Output Analysis, hydrology, software engineering and functional modelling. Catchment Metabolism introduces a holistic perspective in asset management and expands its scope. The schema enables the conceptualisation, modelling and management of catchments as complex asset systems. It, thus, forms the ground for structured collaboration among experts for integrated water resources planning and decision-making. The schema allows for the design and implementation of catchment-based strategies and the assessment of their environmental performance. An industrial case study for a pilot catchment system (Poole Harbour Catchment) is used to demonstrate the application of the Catchment Metabolism. Alternative strategies for nitrogen pollution mitigation are assessed. The application of winter cover crops across the catchment appears to be the optimum strategy. The case study demonstrates the practical and modular implementation of the schema, reveals its methodological strengths and limitations and evaluates its applicability in the asset management planning and decision-making of the water sector.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Papacharalampou, C. (2017). Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/57357/

Chicago Manual of Style (16^th Edition):

Papacharalampou, Chrysoula. “Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach.” 2017. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/57357/.

MLA Handbook (7^th Edition):

Papacharalampou, Chrysoula. “Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach.” 2017. Web. 17 Feb 2019.

Vancouver:

Papacharalampou C. Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach. [Internet] [Doctoral dissertation]. University of Bath; 2017. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/57357/.

Council of Science Editors:

Papacharalampou C. Integrated water resources and asset management at a catchment scale:a life-cycle improvement approach. [Doctoral Dissertation]. University of Bath; 2017. Available from: http://opus.bath.ac.uk/57357/

University of Bath

15. Lawrence, Ruth. N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions.

Degree: phd, 2016, University of Bath

URL: http://opus.bath.ac.uk/57365/

► This thesis is concerned with exploring novel applications of N-oxides as organocatalysts. Specifically, aromatic N-oxides have been successfully implemented as catalysts within the Baeyer-Villiger oxidation… (more)

▼ This thesis is concerned with exploring novel applications of N-oxides as organocatalysts. Specifically, aromatic N-oxides have been successfully implemented as catalysts within the Baeyer-Villiger oxidation of α,β-unsaturated ketones and electrophilic aromatic bromination reactions. Chapter 1 provides a review of the current applications of N-oxides, highlighting their use as organic oxidants, neutral ligands and in particular organocatalysts. These roles exploit several key features of the N-oxide, including the intrinsic weakness and polarity of the N→O bond, their Lewis basicity and ability to function as hydrogen bond acceptors. As organocatalysts, these species have predominantly been utilised as nucleophilic catalysts, however their potential to act as hydrogen bond catalysts represents an emerging area of interest. Chapter 2 describes the development of an organocatalysed Baeyer-Villiger oxidation, for which N-oxides and carboxylates have been identified as suitable catalysts. The optimised protocol, which employs DMAP as the pre-catalyst, was applied to a wide range of saturated and more specifically α,β-unsaturated ketones, with enhanced reaction rates and/or chemoselectivities achieved in the majority of cases. From extensive mechanistic studies, it is proposed that the N-oxide functions as a hydrogen bond acceptor; facilitating concerted proton transfer within the addition step. The unique role of the catalyst allowed for predictions to be made about the rate determining step of the oxidations performed. A series of by-products obtained from the over oxidation of (E)-4-phenyl-3-buten-2-one were characterised and the mechanistic pathway for their formation has been fully elucidated. Development of the reaction conditions for the selective formation of many of these species is also provided. Additionally, the novel reactions of 3-(4-methoxyphenyl)but-3-en-2-one are examined. Chapter 3 details investigations into the applicability of the novel, relatively bench stable formate ester, (formyloxy)(phenyl)methyl acetate, as a formylating reagent. A high yielding and operationally simple procedure for the synthesis of this formate ester from commercially available, inexpensive (E)-4-phenyl-3-buten-2-one is described in Chapter 2. A solvent and catalyst free protocol has been developed for the N-formylation of various amino species including primary and secondary (aliphatic and aromatic) amines and an amino acid ester as well as the O-formylation of alcohols. Demonstrating its synthetic utility, the developed methodology was applied to the one-pot synthesis of an isocyanide from the corresponding amine as well as the N-formylation of an unprotected amino acid under aqueous conditions. Chapter 4 outlines preliminary studies into the application of N-oxides as nucleophilic catalysts for electrophilic aromatic bromination reactions with elemental bromine. The development of novel methodology for the 4-picoline N-oxide catalysed regioselective monobromination of tert-butylbenzene is discussed, for which a reactive…

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Lawrence, R. (2016). N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/57365/

Chicago Manual of Style (16^th Edition):

Lawrence, Ruth. “N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/57365/.

MLA Handbook (7^th Edition):

Lawrence, Ruth. “N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions.” 2016. Web. 17 Feb 2019.

Vancouver:

Lawrence R. N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/57365/.

Council of Science Editors:

Lawrence R. N-Oxides as Organocatalysts for the Baeyer-Villiger Oxidation and Bromination Reactions. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/57365/

University of Bath

16. Petratou, Kleio. Investigating gene regulatory networks underlying zebrafish pigment cell development.

Degree: phd, 2016, University of Bath

URL: http://opus.bath.ac.uk/57367/

► The multipotent cells comprising the vertebrate neural crest (NC) generate an astonishing array of derivatives, including neuronal, skeletal and adrenal components and pigment cells. Zebrafish… (more)

▼ The multipotent cells comprising the vertebrate neural crest (NC) generate an astonishing array of derivatives, including neuronal, skeletal and adrenal components and pigment cells. Zebrafish possess three chromatophores lineages, melanophores, iridophores and xanthophores, which lend themselves to investigating the complex gene regulatory networks (GRNs) underlying fate segregation of NC progenitors. Although the core GRN governing melanophore specification has been previously established, those guiding iridophore and xanthophore development remain elusive. This study explores the iridophore specification GRN via a previously employed systems biology approach. Loss and gain of function experiments were used to derive a preliminary GRN (model A), mathematically modelled using a system of differential equations and computationally simulated to predict gene expression dynamics. Predictions were experimentally evaluated and testable hypotheses were derived to render simulations of the resulting model B consistent with experimental observations. Iterations of this process led to a more sophisticated model D, which accurately predicted observed expression dynamics. Firstly, mutant phenotypes identified the transcription factors Sox10, Tfec and Mitfa and the receptor tyrosine kinase, Ltk, as key players for model A. Regulatory interactions were derived by analysing the spatiotemporal gene expression patterns on wild-type and mutant embryos by in situ hybridisation. Data indicated a sox10-dependent tfec/ltk positive feedback loop driving iridophore specification. Cycles of mathematical modelling and experimentation revealed important regulatory features, such as sox10 maintenance throughout iridophore development and its cooperation with tfec to activate the differentiation gene, pnp4a. Candidate repressors of mitfa, a melanocyte-specific target of sox10, were investigated. Surprisingly, data presented challenge the reported role of Foxd3, an established mitfa repressor, in iridophores. This study established the core GRN guiding specification of the NC-derived iridophore lineage using systems biology. Presented results reveal previously unacknowledged molecular mechanisms underlying fate choice and demonstrate the value of integrating experimental and mathematical approaches when investigating GRNs.

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APA (6^th Edition):

Petratou, K. (2016). Investigating gene regulatory networks underlying zebrafish pigment cell development. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/57367/

Chicago Manual of Style (16^th Edition):

Petratou, Kleio. “Investigating gene regulatory networks underlying zebrafish pigment cell development.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/57367/.

MLA Handbook (7^th Edition):

Petratou, Kleio. “Investigating gene regulatory networks underlying zebrafish pigment cell development.” 2016. Web. 17 Feb 2019.

Vancouver:

Petratou K. Investigating gene regulatory networks underlying zebrafish pigment cell development. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/57367/.

Council of Science Editors:

Petratou K. Investigating gene regulatory networks underlying zebrafish pigment cell development. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/57367/

University of Bath

17. Rushworth, Andrew. Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates.

Degree: phd, 2017, University of Bath

URL: http://opus.bath.ac.uk/57368/

► This thesis ‘’Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates.’’ encompasses a range of research areas,… (more)

▼ This thesis ‘’Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates.’’ encompasses a range of research areas, all under the umbrella of chemical vapour deposition (CVD). Within this report, two types of deposition techniques are compared, high temperature CVD and aerosol assisted CVD (AA-CVD). Chapter 1 presents an up-to-date review of the literature landscape pertaining to graphene and graphene-like materials, including their history, synthesis and properties. Additionally, the various CVD techniques and growth mechanisms are presented. In Chapter 2 we describe the design and use of a CVD reactor to produce graphene. It was found through optimisation of reaction conditions, graphene could be grown on cm length scales on copper foil. Graphene samples were then successfully transferred onto SiO2 substrates, onto which tin sulphides and tungsten disulphide could be grown. An atomic layer deposition (ALD) technique was also used to deposit graphitic carbon films onto copper foil at temperatures as low as 250 °C, which could be transferred to SiO2 without the need of a polymer support. Chapter 3 explores the CVD of tungsten disulphide (WS2) on various substrates including CVD grown graphene. The first example of the AACVD of WS2 onto graphene is reported, where it was shown films as thin as 5 nm could be grown. Using high temperature CVD of tungsten oxide and sulphur, monolayer WS2 was also successfully grown on silicon dioxide and graphene. The characteristic photoluminescent response of monolayer WS2 could be observed on graphene. Materials were analysed using microscopy and spectroscopic techniques such as scanning electron microscopy (SEM), atomic force microscopy (AFM), Raman spectroscopy and powder x-ray diffraction (PXRD). These techniques identified the increased orientation of WS2 deposited onto graphene versus amorphous substrates. Chapter 4 presents findings on how depositing onto graphene substrates may affect the growth and behaviour of tin sulphide materials. Using high temperature CVD, the largest tin sulphide single crystals grown to date from CVD are reported. At lower deposition temperatures, we report the first examples of tin and sulphides deposited onto graphene using an AA-CVD approach. The photoactivity of the tin sulphide-graphene heterostructures has been successfully analysed using photoelectrochemical techniques, where it was found the quality of the graphene substrate had a large effect on device performance. Additionally, bandgaps of the tin sulphides were affected when deposited onto graphene, indicating graphene substrates effect strain in heterostructure materials. As with WS2 depositing onto graphene altered the orientation of tin disulphide, which could be observed by SEM, AFM and PXRD.

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APA (6^th Edition):

Rushworth, A. (2017). Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/57368/

Chicago Manual of Style (16^th Edition):

Rushworth, Andrew. “Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates.” 2017. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/57368/.

MLA Handbook (7^th Edition):

Rushworth, Andrew. “Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates.” 2017. Web. 17 Feb 2019.

Vancouver:

Rushworth A. Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates. [Internet] [Doctoral dissertation]. University of Bath; 2017. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/57368/.

Council of Science Editors:

Rushworth A. Heterostructures from Chemical Vapour Deposition. The Synthesis and Characterisation of Tungsten and Tin Chalcogenides on Graphene Substrates. [Doctoral Dissertation]. University of Bath; 2017. Available from: http://opus.bath.ac.uk/57368/

University of Bath

18. Lazetic, Predrag. The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries.

Degree: phd, 2017, University of Bath

URL: http://opus.bath.ac.uk/57374/

► This thesis investigates the diversity in job quality of university graduates in 17 European countries using multilevel regression modelling, based on combined REFLEX and HEGESCO… (more)

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APA (6^th Edition):

Lazetic, P. (2017). The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/57374/

Chicago Manual of Style (16^th Edition):

Lazetic, Predrag. “The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries.” 2017. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/57374/.

MLA Handbook (7^th Edition):

Lazetic, Predrag. “The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries.” 2017. Web. 17 Feb 2019.

Vancouver:

Lazetic P. The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries. [Internet] [Doctoral dissertation]. University of Bath; 2017. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/57374/.

Council of Science Editors:

Lazetic P. The differences in job quality among higher education graduates in Europe:a cross-national analysis of 17 countries. [Doctoral Dissertation]. University of Bath; 2017. Available from: http://opus.bath.ac.uk/57374/

University of Bath

19. Mahmod, Nor. Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes.

Degree: PhD, 2015, University of Bath

URL: http://opus.bath.ac.uk/49074/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678848

► Cassava is the sixth most important food crop in the world, where it is the staple food for over 500 million people. Its ability to… (more)

▼ Cassava is the sixth most important food crop in the world, where it is the staple food for over 500 million people. Its ability to grow on marginal soil conditions and under minimal care makes cassava a vital ‘food security’ crop for resource-poor farmers. However, cassava production is constrained by post-harvest physiological deterioration (PPD), a storage root disorder characterised by vascular streaking and discolouration of parenchymal tissue. PPD, which renders the roots unpalatable and unmarketable, leads to significant yield loss in global cassava production. The cause of PPD is not yet fully understood but accumulation of reactive oxygen species (ROS) has been observed in the harvested storage root. It is hypothesised that the ROS, which is triggered by wounding during harvesting, is not modulated due to deficiencies in the ROS-detoxifying system in cassava roots, causing oxidative stress to occur, which then leads to symptom formation. To investigate this, transgenic cassavas containing five separate anti-oxidant genes were studied– superoxide dismutase (SOD), ascorbate peroxidase (APX), catalase (CAT), gamma glutamyl cysteine synthetase (GCS) and galacturonic acid reductase (GAR). Each gene was controlled by a root-specific promoter, Patatin, which is also wound-inducible. A high percentage of single-insert lines were recovered, which retained the outward phenotype of WT cassava. While this enabled comparative PPD assessment between the transgenics and the WT, this was complicated by the challenge of reproducibly measuring PPD in greenhouse-grown plants. Therefore, a reliable assay to measure PPD in greenhouse-grown samples was developed and a robust method to assess the symptoms with high confidence was devised. Scopoletin, a fluorescent compound was initially tested as an alternative PPD marker but was dismissed as it did not correlate well with PPD symptom development. Overexpression of anti-oxidant genes was observed in selected lines – between 4- to 5-fold increase of relative transcriptional level was achieved in fresh roots and up to 20-fold was achieved in transgenic roots that had been harvested after 24 hours. However, as the increase did not alter the activity of anti-oxidant enzymes, the transgenic cassava plants generally exhibited similar levels of tolerance to oxidative stress and PPD as the WT plants. This result may be partly due to the difficulty of producing sufficient numbers of replicates for analysis, the behaviour of the Patatin promoter in cassava, and the complexity of anti-oxidant responses. Hence, while this thesis has clarified aspects of the PPD response in cassava and the role of anti-oxidant genes in it, it has not been able to identify definitive means to control the problem through altering the expression of individual genes.

Subjects/Keywords: 633.6

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APA (6^th Edition):

Mahmod, N. (2015). Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/49074/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678848

Chicago Manual of Style (16^th Edition):

Mahmod, Nor. “Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes.” 2015. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/49074/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678848.

MLA Handbook (7^th Edition):

Mahmod, Nor. “Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes.” 2015. Web. 17 Feb 2019.

Vancouver:

Mahmod N. Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes. [Internet] [Doctoral dissertation]. University of Bath; 2015. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/49074/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678848.

Council of Science Editors:

Mahmod N. Analysis of post-harvest physiological deterioration in cassava transformed with anti-oxidant genes. [Doctoral Dissertation]. University of Bath; 2015. Available from: http://opus.bath.ac.uk/49074/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678848

University of Bath

20. Bhooshan, Shajay. Interactive design of curved-crease-folding.

Degree: PhD, 2016, University of Bath

URL: http://opus.bath.ac.uk/48924/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678856

► Building on the historic work of Huffman (Demaine et al. 2011), there has been increasing recent interest in the digital design and architectural application of… (more)

Subjects/Keywords: 620

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APA (6^th Edition):

Bhooshan, S. (2016). Interactive design of curved-crease-folding. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/48924/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678856

Chicago Manual of Style (16^th Edition):

Bhooshan, Shajay. “Interactive design of curved-crease-folding.” 2016. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/48924/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678856.

MLA Handbook (7^th Edition):

Bhooshan, Shajay. “Interactive design of curved-crease-folding.” 2016. Web. 17 Feb 2019.

Vancouver:

Bhooshan S. Interactive design of curved-crease-folding. [Internet] [Doctoral dissertation]. University of Bath; 2016. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/48924/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678856.

Council of Science Editors:

Bhooshan S. Interactive design of curved-crease-folding. [Doctoral Dissertation]. University of Bath; 2016. Available from: http://opus.bath.ac.uk/48924/ ; http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.678856

University of Bath

21. Pasic, Vedad. New vacuum solutions for quadratic metric–affine gravity.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/14074/

► In this thesis we deal with quadratic metric–affine gravity, which is an alternative theory of gravity. We present new vacuum solutions for this theory and… (more)

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APA (6^th Edition):

Pasic, V. (2009). New vacuum solutions for quadratic metric–affine gravity. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/14074/

Chicago Manual of Style (16^th Edition):

Pasic, Vedad. “New vacuum solutions for quadratic metric–affine gravity.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/14074/.

MLA Handbook (7^th Edition):

Pasic, Vedad. “New vacuum solutions for quadratic metric–affine gravity.” 2009. Web. 17 Feb 2019.

Vancouver:

Pasic V. New vacuum solutions for quadratic metric–affine gravity. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/14074/.

Council of Science Editors:

Pasic V. New vacuum solutions for quadratic metric–affine gravity. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/14074/

University of Bath

22. Booth, Tony. ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/14953/

► This research addresses pedagogy in relation to Information & Communication Technology (ICT) in secondary education. Computers have been used in classrooms for approximately thirty years,… (more)

▼ This research addresses pedagogy in relation to Information & Communication Technology (ICT) in secondary education. Computers have been used in classrooms for approximately thirty years, but it remains unclear whether teachers’ pedagogies have changed much in consequence. Thus this research explores the transformation of pedagogy through Information and Communication Technology (ICT). In 1998 a 2-year, multi-site case study linking teams of students and teachers within four broad UK regions was begun. A further six-year period allowed analysis of research data, to support theory building in relation to transformation of teachers’ pedagogy and the conditions necessary to make pedagogical transformation possible. The research made use of Grounded Theory within a case study methodology. Varied data were collected through my records of planning meetings with teachers and engineers during the project; of pedagogical transformation while visiting schools involved in the project; of teachers’, engineers’ and pupils’ case study interview data where more insightful and directly focused questions on pedagogical issues from their different perspectives were involved, and of teachers’ subject knowledge arising from the combined school and industrial manufacturing situated context of the project. The case study interviews involved a representative sample of those taking part in the two-year school and industry project. Theory on pedagogical transformation has resulted from the analysis of these data. Developing this involved modelling alternative meanings of phenomena observed during the case study and developing new concepts as building blocks of the theory. I also used NVivo as a tool to help with handling the mass of raw data collected during the project and with aspects of the qualitative data management. The research concludes that teachers may personally reconstruct their pedagogies when faced in certain ways with certain new pedagogy precedents, and develops precedence as a pre-condition of pedagogical transformation.

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APA (6^th Edition):

Booth, T. (2009). ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/14953/

Chicago Manual of Style (16^th Edition):

Booth, Tony. “ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/14953/.

MLA Handbook (7^th Edition):

Booth, Tony. “ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching.” 2009. Web. 17 Feb 2019.

Vancouver:

Booth T. ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/14953/.

Council of Science Editors:

Booth T. ICT and Pedagogy in the Context of Transformation and Design & Technology Teaching. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/14953/

University of Bath

23. Wells, Maxine H. A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15589/

► This thesis identifies the nature of the values that students hold about business and whether they are acquired through education; the uniformity of the transmission/communication… (more)

▼ This thesis identifies the nature of the values that students hold about business and whether they are acquired through education; the uniformity of the transmission/communication process is addressed. The study traces the views of policy makers and teachers in the policy chain, interviews students and observes classroom interactions in a longitudinal study. The research has been conducted at a time of increasing student numbers on Business Studies courses and during an ongoing debate about the sources of values students hold about business. A distinction is drawn between the values intrinsic to AngloAmerican capitalism and the values that students espouse enabling insight as to whether students are taught and hold AngloAmerican capitalist values or not. Other sources of values such as gender and students’ parttime jobs are considered. Seven policy makers (individuals influencing the creation of the ‘hidden’ or ‘overt’ curriculum) and four groups comprising ‘A’ level and GNVQ Advanced in Business Studies students and their respective teachers participated in the research. The study draws the following conclusions: students, typically, see profit as the primary business objective and this view is framed by the values intrinsic to AngloAmerican capitalism, with other values such as customer service seen as ‘instrumental’ in the pursuit of profitability. Values intrinsic to AngloAmerican capitalism were not directly being transmitted down the policy chain; however, work socialisation values were. The students were able to distinguish between their own personal values and those of business organisations; their personal values often conflicted with those of business. Factors extraneous to education, for example, students’ parttime jobs appear to have a greater influence over their knowledge of business values than that of their teachers. The students often expressed scepticism at business activities, despite no clear evidence that teachers ‘transmit’ antibusiness sentiments. Gender had some influence on the values that students held.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wells, M. H. (2009). A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15589/

Chicago Manual of Style (16^th Edition):

Wells, Maxine H. “A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15589/.

MLA Handbook (7^th Edition):

Wells, Maxine H. “A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies.” 2009. Web. 17 Feb 2019.

Vancouver:

Wells MH. A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15589/.

Council of Science Editors:

Wells MH. A policy inquiry into the development of Business Studies within the curriculum in England focussing on the transmission of implicit and explicit values within ‘A’ Level and GNVQ Advanced Business Studies. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15589/

University of Bath

24. Webb, Adam. An Investigation into the Role of Protein Kinases in T lymphocyte Migration.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15590/

► The migration of T lymphocytes is a vital component of the immune system, with roles in immunosurveillance and inflammation. The role of Phosphoinositide 3-kinase within… (more)

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APA (6^th Edition):

Webb, A. (2009). An Investigation into the Role of Protein Kinases in T lymphocyte Migration. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15590/

Chicago Manual of Style (16^th Edition):

Webb, Adam. “An Investigation into the Role of Protein Kinases in T lymphocyte Migration.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15590/.

MLA Handbook (7^th Edition):

Webb, Adam. “An Investigation into the Role of Protein Kinases in T lymphocyte Migration.” 2009. Web. 17 Feb 2019.

Vancouver:

Webb A. An Investigation into the Role of Protein Kinases in T lymphocyte Migration. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15590/.

Council of Science Editors:

Webb A. An Investigation into the Role of Protein Kinases in T lymphocyte Migration. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15590/

University of Bath

25. Yousef, Kharsim. Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15591/

► For users away from the office or home, there is an increasing demand for mobile solutions that offer effective collaborative facilities on the move. The… (more)

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APA (6^th Edition):

Yousef, K. (2009). Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15591/

Chicago Manual of Style (16^th Edition):

Yousef, Kharsim. “Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15591/.

MLA Handbook (7^th Edition):

Yousef, Kharsim. “Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices.” 2009. Web. 17 Feb 2019.

Vancouver:

Yousef K. Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15591/.

Council of Science Editors:

Yousef K. Architecture and Remote Interaction Techniques for Digital Media Exchange across 3G Mobile Devices. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15591/

University of Bath

26. Song, Yi Zhe. Hierarchical Image Descriptions for Classification and Painting.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15592/

► The overall argument this thesis makes is that topological object structures captured within hierarchical image descriptions are invariant to depictive styles and offer a level… (more)

▼ The overall argument this thesis makes is that topological object structures captured within hierarchical image descriptions are invariant to depictive styles and offer a level of abstraction found in many modern abstract artworks. To show how object structures can be extracted from images, two hierarchical image descriptions are proposed. The first of these is inspired by perceptual organisation; whereas, the second is based on agglomerative clustering of image primitives. This thesis argues the benefits and drawbacks of each image description and empirically show why the second is more suitable in capturing object strucutures. The value of graph theory is demonstrated in extracting object structures, especially from the second type of image description. User interaction during the structure extraction process is also made possible via an image hierarchy editor. Two applications of object structures are studied in depth. On the computer vision side, the problem of object classification is investigated. In particular, this thesis shows that it is possible to classify objects regardless of their depictive styles. This classification problem is approached using a graph theoretic paradigm; by encoding object structures as feature vectors of fixed lengths, object classification can then be treated as a clustering problem in structural feature space and that actual clustering can be done using conventional machine learning techniques. The benefits of object structures in computer graphics are demonstrated from a Non-Photorealistic Rendering (NPR) point of view. In particular, it is shown that topological object structures deliver an appropriate degree of abstraction that often appears in well-known abstract artworks. Moreover, the value of shape simplification is demonstrated in the process of making abstract art. By integrating object structures and simple geometric shapes, it is shown that artworks produced in child-like paintings and from artists such as Wassily Kandinsky, Joan Miro and Henri Matisse can be synthesised and by doing so, the current gamut of NPR styles is extended. The whole process of making abstract art is built into a single piece of software with intuitive GUI.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Song, Y. Z. (2009). Hierarchical Image Descriptions for Classification and Painting. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15592/

Chicago Manual of Style (16^th Edition):

Song, Yi Zhe. “Hierarchical Image Descriptions for Classification and Painting.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15592/.

MLA Handbook (7^th Edition):

Song, Yi Zhe. “Hierarchical Image Descriptions for Classification and Painting.” 2009. Web. 17 Feb 2019.

Vancouver:

Song YZ. Hierarchical Image Descriptions for Classification and Painting. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15592/.

Council of Science Editors:

Song YZ. Hierarchical Image Descriptions for Classification and Painting. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15592/

University of Bath

27. Witkowska, Agata. Post-processing of Photonic Crystal Fibres and Standard Fibres.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15594/

► This thesis describes work on fibre transitions made in photonic crystal fibres (PCF) and conventional standard fibres. Three post-processing techniques were used to make the… (more)

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APA (6^th Edition):

Witkowska, A. (2009). Post-processing of Photonic Crystal Fibres and Standard Fibres. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15594/

Chicago Manual of Style (16^th Edition):

Witkowska, Agata. “Post-processing of Photonic Crystal Fibres and Standard Fibres.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15594/.

MLA Handbook (7^th Edition):

Witkowska, Agata. “Post-processing of Photonic Crystal Fibres and Standard Fibres.” 2009. Web. 17 Feb 2019.

Vancouver:

Witkowska A. Post-processing of Photonic Crystal Fibres and Standard Fibres. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15594/.

Council of Science Editors:

Witkowska A. Post-processing of Photonic Crystal Fibres and Standard Fibres. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15594/

University of Bath

28. Hartley, Benjamin C. Recent Advances in Tandem Reductive Processes.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15764/

► The research presented herein is concerned with the exploration of tandem processes initiated by the conjugate reduction of Michael acceptors, encompassing the asymmetric reductive Dieckmann… (more)

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APA (6^th Edition):

Hartley, B. C. (2009). Recent Advances in Tandem Reductive Processes. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15764/

Chicago Manual of Style (16^th Edition):

Hartley, Benjamin C. “Recent Advances in Tandem Reductive Processes.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15764/.

MLA Handbook (7^th Edition):

Hartley, Benjamin C. “Recent Advances in Tandem Reductive Processes.” 2009. Web. 17 Feb 2019.

Vancouver:

Hartley BC. Recent Advances in Tandem Reductive Processes. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15764/.

Council of Science Editors:

Hartley BC. Recent Advances in Tandem Reductive Processes. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15764/

University of Bath

29. Kontovourkis, Odysseas. Computer-generated Circulation Diagrams.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15766/

► The way in which computers are used is important in the theory, philosophy and practice of architecture. Architects are already using computers to construct complex… (more)

▼ The way in which computers are used is important in the theory, philosophy and practice of architecture. Architects are already using computers to construct complex three dimensional geometric models of their buildings and are beginning to analyse these models using environmental and structural software, a development which raises new questions about the role of architects and engineers. This dissertation puts forward the hypothesis that architects will at times need to be actively involved in computer programming by writing or modifying software. The hypothesis is based on the assumption that the form of a building and its spatial configuration are influenced by the nature of the design process itself. If architects are to have a complete and subtle control over design and to identify their own personal aesthetic language, they must also have control over the design process including the way computer software tools are developed and used. The hypothesis is tested using the example of a ferry terminal, a building type whose function is largely dominated by passenger circulation. Even thought passengers have a very straightforward aim to reach their final destination, the rules governing the way passengers move around the building are complex and a single computer program will not be able to cover all possible aspects of such behaviour. Thus, architects must have the freedom to formulate different rules and study the effects they have on their design. This particularly applies in non-emergency situations when each individual moves inside the building according to different needs and desires. A program was written which runs in real time so that the architect can see the effect of changing the parameters that control the process. The program can be used as evaluation mechanism to study the performance of postulated design or it can be use as creative mechanism where the design may emerge out of the process in the same way that animals create paths in the woods. Either way, the general aim is to optimize the design according to criteria over which the architect, again, must have complete control.

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APA (6^th Edition):

Kontovourkis, O. (2009). Computer-generated Circulation Diagrams. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15766/

Chicago Manual of Style (16^th Edition):

Kontovourkis, Odysseas. “Computer-generated Circulation Diagrams.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15766/.

MLA Handbook (7^th Edition):

Kontovourkis, Odysseas. “Computer-generated Circulation Diagrams.” 2009. Web. 17 Feb 2019.

Vancouver:

Kontovourkis O. Computer-generated Circulation Diagrams. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15766/.

Council of Science Editors:

Kontovourkis O. Computer-generated Circulation Diagrams. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15766/

University of Bath

30. Williams, Nathan M. Active Flow Control on a Nonslender Delta Wing.

Degree: phd, 2009, University of Bath

URL: http://opus.bath.ac.uk/15950/

► The effects of active flow control by oscillatory blowing at the leading edge of a nonslender delta wing with a Λ=50° sweep angle have been… (more)

▼ The effects of active flow control by oscillatory blowing at the leading edge of a nonslender delta wing with a Λ=50° sweep angle have been investigated. Pressure measurements and Particle Image Velocimetry measurements were conducted on a half wing to investigate the formation of leading edge vortices for oscillatory blowing, compared to the stalled flow for the no blowing case. Stall has been delayed by up to 8, and significant increases in the upper surface suction force have been observed. Velocity measurements show that shear layer reattachment is promoted with forcing, and a vortex flow pattern develops. The time averaged location of the centre of the vortical region moves outboard with increased excitation. The near-surface flow pattern obtained from the PIV measurements shows reattachment in the forward part of the wing. There is no measurable jet-like axial flow in the vortex core, which seems to break down at or very near the apex. This highlights that unlike slender delta wings, vortex breakdown is not a limiting factor in the generation of lift for nonslender delta wings. Phase averaged measurements reveal the perturbation due to the pulsed blowing, its interaction with the shear layer and vortex, apparent displacement of the vortex core, and relaxation of the reattachment region. The flow in a phase averaged sense is highly three dimensional. Experiments indicate that unsteady blowing at Strouhal numbers in the region of St=0.5 to St=0.75, and in the region of St=1.25 to St=1.5 can be a highly effective. Reattached flow can develop from stalled flow after pulsing has been initiated with a time constant of tU/c=5 for unsteady blowing at St=0.75, and tU/c=7 for St=1.5. Experiments with excitation from finite span slots located in the forward half of the wing show that partial blowing can be more effective at low momentum coefficients. Force measurements of a full delta wing confirmed that the effectiveness of this method of flow control was not only confined to half delta wings.

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APA (6^th Edition):

Williams, N. M. (2009). Active Flow Control on a Nonslender Delta Wing. (Doctoral Dissertation). University of Bath. Retrieved from http://opus.bath.ac.uk/15950/

Chicago Manual of Style (16^th Edition):

Williams, Nathan M. “Active Flow Control on a Nonslender Delta Wing.” 2009. Doctoral Dissertation, University of Bath. Accessed February 17, 2019. http://opus.bath.ac.uk/15950/.

MLA Handbook (7^th Edition):

Williams, Nathan M. “Active Flow Control on a Nonslender Delta Wing.” 2009. Web. 17 Feb 2019.

Vancouver:

Williams NM. Active Flow Control on a Nonslender Delta Wing. [Internet] [Doctoral dissertation]. University of Bath; 2009. [cited 2019 Feb 17]. Available from: http://opus.bath.ac.uk/15950/.

Council of Science Editors:

Williams NM. Active Flow Control on a Nonslender Delta Wing. [Doctoral Dissertation]. University of Bath; 2009. Available from: http://opus.bath.ac.uk/15950/

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