publisher:("Trinity College Dublin")

1. RIEDER, MARIA. Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant.

Degree: 2015, Trinity College Dublin

► The Irish Traveller community is traditionally a nomadic minority group that has very much held on to their own lifestyle, customs, and values. An important… (more)

▼ The Irish Traveller community is traditionally a nomadic minority group that has very much held on to their own lifestyle, customs, and values. An important component of their cultural heritage is Cant, a communicative code composed of Cant lexical items and an English morphosyntactical framework and used for private, in-group conversation. Due to its oral nature, which entails that there is little written historical evidence, and the secrecy with which it is often guarded, the information about it is very limited. This thesis asks what folk linguistics can contribute to our existing knowledge about Cant and its role in the Traveller community. Three points justify a folk linguistic perspective. Firstly, this study intends to enhance our knowledge about Cant. Due to the scarcity of material we can only find out more about it by speaking to the community. This thesis provides new material in the form of speakers? descriptions and interpretations of the nature and use of Cant. Secondly, language use and folk views about language are deeply interwoven with the language ideology of a group and with how community members view themselves in society. By taking a folk linguistic approach we not only gain functional and pragmatic information about Cant, but we also learn about beliefs and attitudes that govern speakers? language use and how language stands in relation to other elements in the cultural and linguistic repertoire. This latter point leads to the third rationale. Its interrelationship with other cultural elements means that language is in a constant flux. A folk linguistic study is about speakers? experiences of language in action, and therefore gives a dynamic view of language use. Folk-beliefs about Cant were studied during a two-year ethnographic project in two small communities of practice. The data consists of ethnographic fieldnotes and focus group interviews and were analysed by a combination of Ethnography of Communication and Critical Discourse Analysis.

Subjects/Keywords: Cant, Gammon, Irish Travellers, Folk Linguistics, Ethnography of Communication, Critical Discourse Analysis, Community of Practice, Sociolinguistics; Identities in Transformation; Inclusive Society; Intelligent Content & Communications; Making Ireland; Cant; Ethnography; Ethnography of Communication; Folk Linguistics; Gammon; Linguistic Anthropology; Shelta; bilingualism and multilingualism; irish travellers

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

RIEDER, M. (2015). Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/75310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

RIEDER, MARIA. “Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant.” 2015. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/75310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

RIEDER, MARIA. “Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant.” 2015. Web. 27 Feb 2020.

Vancouver:

RIEDER M. Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant. [Internet] [Thesis]. Trinity College Dublin; 2015. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/75310.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

RIEDER M. Codes in Transition: A Folk Linguistic Exploration of the Irish Traveller Cant. [Thesis]. Trinity College Dublin; 2015. Available from: http://hdl.handle.net/2262/75310

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. KELLY, STEPHEN. News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets.

Degree: 2016, Trinity College Dublin

URL: http://hdl.handle.net/2262/79727

► With the advent of the internet and digitisation of news and books, the volume of unstructured text has increased dramatically in recent years. This deluge… (more)

▼ With the advent of the internet and digitisation of news and books, the volume of unstructured text has increased dramatically in recent years. This deluge of information is set to grow and come from new and unconventional sources. New and innovative techniques and tools for manipulating this data and making sense of it will become essential. The work in this thesis consists of a system that analyses the content of news, extracting a sentiment time series variable, and uses this variable in a time series modelling component to determine any inter-relationships between changes in the price of financial assets. Each component of the system attempts to remove human subjectivity from the modelling process to allow the system to compute a sentiment variable and investigate its statistical significance and explanatory power by employing several time series models. The system includes a number of processes and components to achieve this goal such as data harvesting, processing, text analysis, time series modelling, hypothesis testing, and visualisation. The work described in this thesis includes contributions to the area of text and content analysis, information retrieval, time series analysis, statistical and econometric modelling. A number of methods studied in the literature have incorporated text data with financial analysis and prediction models. A review of some of the main studies and systems that have combined methods from each discipline is presented in Chapter 2. Chapter 3 describes the system developed in this thesis and its capabilities. The system is evaluated for different data inputs in Chapter 4, where the influence of different news types and sources is investigated for equity and commodity markets. The final chapter concludes the thesis by summarising the contributions and outlining future work. This thesis represents a combination of work that contributes to the areas of content analysis and financial and statistical modelling. The main contribution of this thesis is in the implementation and evaluation of a system that incorporates methods from text analysis and time series modelling. The novelty of the system lies in the ability to compute a time series from text that acts as a proxy for sentiment that can be aggregated with financial time series data in a statistical model to estimate the impact of news on the financial asset. An evaluation of this system is presented where the explanatory power of the sentiment variable for financial returns is investigated. It is shown that the news source and text type play an important role when computing a proxy for sentiment that has statistically significant explanatory power for financial returns. The time varying influence of sentiment on financial returns is noted with a relationship made between economic business cycles and volatility. The system is evaluated using data from two financial markets, the equity and commodities markets, and in both instances it is found that a proxy for sentiment extracted from news has a statistically significant influence on… Advisors/Committee Members: AHMAD, KHURSHID.

Subjects/Keywords: Data Analysis; Econometric and statistical analysis; Natural Language Processing; STATISTICAL ANALYSIS

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

KELLY, S. (2016). News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/79727

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

KELLY, STEPHEN. “News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets.” 2016. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/79727.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

KELLY, STEPHEN. “News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets.” 2016. Web. 27 Feb 2020.

Vancouver:

KELLY S. News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets. [Internet] [Thesis]. Trinity College Dublin; 2016. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/79727.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

KELLY S. News, Sentiment, and Financial Markets: A Computational System to Evaluate the Influence of Text Sentiment on Financial Assets. [Thesis]. Trinity College Dublin; 2016. Available from: http://hdl.handle.net/2262/79727

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

3. Stefanazzi, Mary. The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology.

Degree: School of Religions,Theology & Ecumenics. Loyola Institute, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/79899

► The research aim of this study is to determine the contemporary relevance of the collaboration between Victor White, theologian, and Carl Gustav Jung the founder… (more)

▼ The research aim of this study is to determine the contemporary relevance of the collaboration between Victor White, theologian, and Carl Gustav Jung the founder of Analytical Psychology. There are three objectives. The first is to place White s interest in Jung in a personal, professional and ecclesiastical context. Secondly, the intention is to try to understand the impasse that occurred between Jung and White about how evil is understood. The third objective of this thesis is to demonstrate that White s work, exploring the interdisciplinary frontier of theology and psychology is both valuable in its own terms, and of contemporary significance. This work explores the narrative of human flourishing based on a study of the interdisciplinary dialogue between White and Jung. The Jung-White dialogue is of particular interest because it demonstrates the challenge and the value of rigorous interdisciplinary engagement. Although theology and psychology each share the same subject matter the human person the distinction lies in the way in which the subject is knowable. White s investigation of the identity of soul and psyche demonstrates how the understanding of soul as a concept is reached by philosophical inference in theology. Inference is a different methodology to the field of investigation of the empirical psychologist. This work demonstrates that in working from two different methodologies the collaboration between Jung and White enabled conflicts in understanding to come to light that were unlikely to have been identified otherwise. This work recommends White s rational anthropology, which is grounded in the tradition of Aristotle and Aquinas, as a basis for interdisciplinary dialogue with view to paving the way towards a general consensus on what it means to be a flourishing human person. The aim is to draw attention to the value of White s scholarship as a potentially significant contribution to contemporary discourse on mental health. In providing a philosophical / theological / psychological synthesis of the flourishing human person White s corpus has much to contribute towards a greater understanding of what constitutes mental health. Although the times we live in have changed considerably, the essence of the human condition has not. Advisors/Committee Members: Ryan, Fainche.

Subjects/Keywords: Victor White OP; Human Flourishing; Carl Jung; Mental Health; Aquinas; Theology; Aristotle; Interdisciplinary research; Evil; Eranos; Jung-White dialogue; The common ground of Theology and Analytical Psychology; Identity of 'soul' and 'psyche'; Victor White OP on Rational Anthropology; Philosophical / Theological / Psychological synthesis of the flourishing human person; The human condition

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Stefanazzi, M. (2017). The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/79899

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Stefanazzi, Mary. “The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/79899.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Stefanazzi, Mary. “The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology.” 2017. Web. 27 Feb 2020.

Vancouver:

Stefanazzi M. The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/79899.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stefanazzi M. The Narrative of Human Flourishing: A study of the dialogue between Victor White (Theologian) and Carl Jung (Analytical Psychology) on the frontier between Theology and Psychology. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/79899

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

4. O'BRIEN, MARIA. Synthesis and raman characterisation of transition metal dichalcogenides.

Degree: School of Chemistry. Discipline of Chemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/80557

► In recent years there has been an increased interest in layered materials such as Transition Metal Dichalcogenides (TMDs). When isolated in their monolayer form, they… (more)

▼ In recent years there has been an increased interest in layered materials such as Transition Metal Dichalcogenides (TMDs). When isolated in their monolayer form, they are essentially a 2D material, with unique properties. The implementation of 2D materials into future electronic devices could be desirable for industry; as their potential applications include cheap, fast and flexible electronic devices. Furthermore, to fully exploit the unique electrical properties of these materials, such as high electron mobility, new synthesis, manipulation, integration and characterisation techniques must be developed. The first part of this thesis focuses on the reliable vapour phase synthesis of TMDs. Initial research focused on the thermally assisted chalcogenisation of pre-deposited layers. The successful growth of crystalline, uniform thin films of MoS2 indicated that this process was a significant step towards growth of TMD films in a manner compatible with techniques used in the semiconductor industry. Electrical transport in WS2 films was highly sensitive to the presence of NH3 gas, which was the first reported demonstration of a gas sensing response for WS2 thin films. A sensitivity of 1.4 ppm NH3 in nitrogen at room temperature was achieved, indicating device sensitivity comparable with commercially available metal-oxide-semiconductor and solid electrolyte sensors. However, films produced using these methods were typically polycrystalline, and therefore ?bottom-up? chemical vapour phase synthesis methods were required to create single crystals with a high degree of crystallinity in the lattice. Highly crystalline TMD monolayers were realised by using a close proximity precursor supply in a microreactor setup. Monolayer TMD single crystals were synthesised with high reproducibility. A wide range of spectroscopic, microscopic, and electrical characterisation techniques reveal the high quality of the TMD samples produced, which could be used in the future for the facile production of electronic device components. The second part of this thesis focuses on the spectroscopic characteristics of vapour phase grown TMDs. Raman characterisation of vapour phase grown PtSe2 thin polycrystalline films is presented. PtSe2 thin films were grown by conversion of Pt films to PtSe2 at low temperatures under Se atmosphere. Scanning transmission electron microscopy measurements of these films experimentally confirmed the crystal structure to be 1T, which allowed predictions to be made of the phonon dispersion curve and expected frequencies of vibrational modes. These modes were experimentally confirmed and found to depend on film thickness for a variety of laser excitation wavelengths. Chemical vapour deposition (CVD) grown TMDs were studied using low-frequency Raman spectroscopy. This allowed the measurement of the shear and layer-breathing modes in the multilayer crystals, which were visualised in maps. It was found that these low-energy Raman modes allowed the assessment of layer number, as well as stacking configuration (2H or 3R), of… Advisors/Committee Members: Duesberg, Georg.

Subjects/Keywords: Raman; Chemical Vapour Deposition; Transition Metal Dichalcogenides

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

O'BRIEN, M. (2017). Synthesis and raman characterisation of transition metal dichalcogenides. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80557

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'BRIEN, MARIA. “Synthesis and raman characterisation of transition metal dichalcogenides.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80557.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'BRIEN, MARIA. “Synthesis and raman characterisation of transition metal dichalcogenides.” 2017. Web. 27 Feb 2020.

Vancouver:

O'BRIEN M. Synthesis and raman characterisation of transition metal dichalcogenides. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80557.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'BRIEN M. Synthesis and raman characterisation of transition metal dichalcogenides. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/80557

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. MUNSHI, RAAFAT MOHAMMED. The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer.

Degree: School of Medicine. Discipline of Clinical Medicine, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/80368

► Fusobacterium nucleatum, a gram-negative spindle-shaped anaerobic bacterium, is a component of the human microbiome that primarily inhabits the oral cavity and is associated with many… (more)

▼ Fusobacterium nucleatum, a gram-negative spindle-shaped anaerobic bacterium, is a component of the human microbiome that primarily inhabits the oral cavity and is associated with many diseases, including sinusitis, tonsillitis, urinary tract infection, and inflammatory bowel disease. Recent research demonstrates an association between the presence of this bacterium and colorectal carcinoma. This study aimed to investigate the ability of this bacterium and its outer membrane vesicles (OMV) to modulate colonic cell function. Like other gram-negative bacteria, F. nucleatum secretes OMV, but little is known about how they interact with host tissue. To investigate the potential role of these structures in the host-pathogen interaction the OMV were purified, proteomically characterised and their interaction with colonic cells investigated. In this regard, the mass spectrometry-based proteomic analysis revealed the presence of 366 proteins including several biologically active proteases which appeared to be selectively enriched in the OMV. In addition, many other proteins with documented or likely roles in F. nucleatum-mediated pathogenesis were identified. The ability of the F. nucleatum OMV to modulate several colonic epithelial cellular behaviours was investigated and compared with the intact parental bacterium. The OMV induced a potent pro-inflammatory response in colonic epithelial cells, stimulating the expression and secretion of pro-inflammatory cytokines and chemokines. OMV also impaired the barrier function of model colonic epithelial monolayers, in part by degrading the tight junctional protein E-cadherin and down regulating the expression of CDH-1. This process was accompanied by cadherin switching and the induction of a mesenchymal phenotype in the colonic cells as judged prominent morphological changes, significantly increased cellular proliferation and migration and the appearance of several markers associated with EMT, including increased nuclear translocation of the pivotal EMT transcription factor, ZEB-1. Taken together, these findings and the observation that the OMV enhanced colonic resistance to the chemotherapeutic agent 5-FU, support the hypothesis that these nanostructures likely make a significant contribution to the pathogenesis of gastrointestinal disease in susceptible individuals. Advisors/Committee Members: WINDLE, HENRY.

Subjects/Keywords: Fusobacterium nucleatum; Outer Membrane Vesicles; Colonic; Cancer

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

MUNSHI, R. M. (2017). The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80368

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MUNSHI, RAAFAT MOHAMMED. “The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80368.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MUNSHI, RAAFAT MOHAMMED. “The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer.” 2017. Web. 27 Feb 2020.

Vancouver:

MUNSHI RM. The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80368.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MUNSHI RM. The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/80368

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

6. RODDY, STEPHEN. Embodied sonification.

Degree: School of Engineering. Department of Electronic and Electrical Engineering, 2015, Trinity College Dublin

URL: http://hdl.handle.net/2262/80558

► Sonification is the communication of data using sound. This thesis is concerned with meaning-making in sonification. It examines how meaning emerges during sonification listening through… (more)

▼ Sonification is the communication of data using sound. This thesis is concerned with meaning-making in sonification. It examines how meaning emerges during sonification listening through the lens of embodied cognitive science. It suggests that approaches to sonification which exploit the embodied nature of meaning-making can leverage aesthetic dimensions of sound which allow for more effective communication. This thesis employs a mixed methods research approach to empirically evaluate dimensions of sound which are traditionally categorised as aesthetic. Hypotheses about the embodied nature of meaning-making in sonification listening are developed through a reading of the literature, through exploration with prototyping platforms, and through exploratory data-driven composition. These hypotheses are then submitted to empirical listener evaluations, from which conclusions about embodied meaning-making in sonification listening can be drawn. Chapter 1 considers sonification in terms of two models of meaning-making: the computationalist model, which reduces meaning-making to information processing, and the embodied model, which treats embodied experience as the basis of all meaning. Aesthetic approaches, scientific approaches and leading sonification techniques are considered in reference to these models and it is argued that the embodied model is of more use to the development of communicatively effective sonifications than the popular computationalist model, which cannot account for the aesthetic dimensions of sound. The Embodied Sonification Listening Model (ESLM) is introduced in Chapter 2 to offer an embodied perspective on meaning-making during sonification listening. Chapter 2 also introduces and defines the Embodied Sonic Dimension and the Embodied Sonic Complex as novel conceptual measurement schemes for working with the aesthetic and embodied dimensions of sound in a sonification context. An empirical evaluation, which describes how a listener?s embodied schematic knowledge influences their interpretation of a sonification, is also presented in this chapter. The ELSM, embodied sonic dimensions and embodied sonic complex represent useful theoretical tools for guiding the design of sonifications, which can exploit the embodied nature of meaning-making to effectively communicate data to a listener. Chapter 3 investigates the communicative effectiveness of some of the embodied sonic dimensions afforded by vocal gestures. It presents a large number of evaluations, the results of which highlight useful synthesis strategies for modelling and controlling these dimensions in a sonification context. The embodied sonic dimensions explored in Chapter 3 represent a means for intuitively communicating data to a listener on the basis of their previous embodied experiences. Chapter 4 investigates the communicative effectiveness of some of the embodied sonic complexes which environmental soundscapes can offer to sonification. The research described in this chapter was intended to develop an embodied soundscape sonification… Advisors/Committee Members: Furlong, Dermot.

Subjects/Keywords: Sonification; Embodied Sonic Dimension; Embodies Sonic Complex; Telecommunications

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

RODDY, S. (2015). Embodied sonification. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80558

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

RODDY, STEPHEN. “Embodied sonification.” 2015. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80558.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

RODDY, STEPHEN. “Embodied sonification.” 2015. Web. 27 Feb 2020.

Vancouver:

RODDY S. Embodied sonification. [Internet] [Thesis]. Trinity College Dublin; 2015. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80558.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

RODDY S. Embodied sonification. [Thesis]. Trinity College Dublin; 2015. Available from: http://hdl.handle.net/2262/80558

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

7. Byrne, Mikaela. An investigation of epigenetic effects in Atherosclerosis.

Degree: School of Medicine. Discipline of Clinical Medicine, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/80565

► Epigenetic mechanisms may explain some of the missing heritability associated with CVD and how external factors such as diet, environment and lifestyle contribute to disease… (more)

▼ Epigenetic mechanisms may explain some of the missing heritability associated with CVD and how external factors such as diet, environment and lifestyle contribute to disease development and progression. This thesis aimed to investigate the role of epigenetics in atherosclerosis- from initiation to plaque development and its subsequent outcomes. Injury to the endothelium and subsequent inflammation represent a critical starting point for atherosclerosis. A primary objective of this study was to evaluate the use of epigenetic targeting agents SFN and SAHA (Vorinostat) on the expression of CXCL16, IL8, IL18 and miR210 and miR145, in TNFα stimulated endothelial (EA.hy926) and macrophage (THP-1) cell lines. The findings of this thesis suggest that the expression of CXCL16, IL8, IL18 and the indicated miRNAs can be altered by histone deacetylase inhibitors SFN and SAHA. However, the amount of HDACi (SFN and SAHA) and duration of treatment may have disparate effects and depend on the pre-existing inflammatory background in this case cytokine levels. This could limit potential use in the clinic. As CXCL16 plays a multifaceted role in all stages of atherosclerosis, genetic variation which influences gene expression is of particular interest. An AEI investigation of the CXCL16 SNP rs2277680 was undertaken to determine allelic expression imbalance in the presence and absence of epigenetic modifying agents. These experiments found that AEI can be induced following treatment with various ETAs, proposing an epigenetic mechanism for AEI. The question remains as to whether all cells produce mRNA from both alleles, albeit at different levels, or one allele is silenced completely (monoallelic expression) and the observations are the result of heterogeneous mixtures of cells with either one or the other allele silenced. However, monoallelic expression is unlikely as AEI can be observed following 6 h treatment, a time point which is too short to be attributed to cell turnover. This study also investigated the stability of AEI over multiple passages during cell culture. These results suggest that AEI is predominately stable, with considerable noise, over cell culture but becomes less predictable with increasing passage number. This study also raises the question as to the effectiveness and reproducibility of using cells which have been frozen in DMSO due to its potential for altering allelic expression imbalance. Finally, the expression of miRNAs 145 and 210 has previously been shown to be reduced in patients with plaques which are prone to rupture. However, an association in stroke recurrence prediction from an initial cardiac event has not been examined. This is the first study to demonstrate an inverse relationship between miR145 and CD68 macrophages in stroke recurrence in a clinical data set. This finding confirms the role of miR145 in CVD, and as a biomarker of decreased stroke recurrence, a potential therapeutic target and predictive marker. Data generated in this study suggest that decreased miR145 expression is… Advisors/Committee Members: Murphy, Ross.

Subjects/Keywords: Atherosclerosis; miRNAs; plaque rupture; epigenetics; AEI; stroke re-currence

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Byrne, M. (2017). An investigation of epigenetic effects in Atherosclerosis. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Byrne, Mikaela. “An investigation of epigenetic effects in Atherosclerosis.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Byrne, Mikaela. “An investigation of epigenetic effects in Atherosclerosis.” 2017. Web. 27 Feb 2020.

Vancouver:

Byrne M. An investigation of epigenetic effects in Atherosclerosis. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80565.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Byrne M. An investigation of epigenetic effects in Atherosclerosis. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/80565

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. COBAIN, EVE CLAIRE. "The soul has ears": Music and movement in the poetry of John Berryman.

Degree: School of English. Discipline of English, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/80588

► "The soul has ears": Music and Movement in the Poetry of John Berryman Berryman?s musical interest is consistently remarked on by readers of his work,… (more)

▼ "The soul has ears": Music and Movement in the Poetry of John Berryman Berryman?s musical interest is consistently remarked on by readers of his work, but remains vastly understudied, though it touches almost every aspect of his poetic project. The poet?s obsession with ?hearing? was one that spilled across from one art form into another, and his musical enthusiasm expresses itself in a way that is all-pervasive. Berryman?s work represents a deep enquiry into the influence of music on the mind and body, as well as its impact on the structures of the poem. As early as The Dispossessed (1948), his first major publication, the song emerges as an emotional yet social medium, and the poet?s interest in the human voice as a form of musical embodiment remains a feature until his final posthumous collection, Delusions, Etc., published in 1972. In fact, all of Berryman?s major poetic works demonstrate a general, and associated, interest in musical personalities ? such as Beethoven, Bach, and Bessie Smith ? particularly those whose experience Berryman felt most resonated with his own. Various musical traditions collide energetically within his work (most famously in The Dream Songs [1969]), and his thematic preoccupations often mark the site of deeper structural engagement. In many of these published works, though particularly Berryman?s Sonnets (1967), there is a further enquiry into the relationship between word and music and an examination of the musical integrity of language per se. Berryman?s musical explorations touch on almost all of his central themes: love, loss and the ability of artistic form to shape to human experience. Across his work, the poet uses music to express both personal and political traumas, and often through it he discovers a means of transcendence. Moreover, Berryman?s sense of memory, terminality and creative legacy emerges consistently in connection with music, themes that take precedence in his final two collections, Love & Fame (1970) and Delusions, Etc. (1972). Reading Berryman?s major books in chronological order, this study demonstrates how music enters the poetry and comes to shape the trajectory of his career. Indeed, as key archival findings show, some of the most notable developments in Berryman?s poetry can be understood as having their basis in his musical thinking, which allowed the poet to step outside his own discipline and enter into a broader creative continuum. Advisors/Committee Members: Matterson, Stephen.

Subjects/Keywords: John Berryman; Music; Poetics; Middle-Generation America; Twentieth-Century American Poetry

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APA (6^th Edition):

COBAIN, E. C. (2017). "The soul has ears": Music and movement in the poetry of John Berryman. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80588

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

COBAIN, EVE CLAIRE. “"The soul has ears": Music and movement in the poetry of John Berryman.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80588.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

COBAIN, EVE CLAIRE. “"The soul has ears": Music and movement in the poetry of John Berryman.” 2017. Web. 27 Feb 2020.

Vancouver:

COBAIN EC. "The soul has ears": Music and movement in the poetry of John Berryman. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80588.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

COBAIN EC. "The soul has ears": Music and movement in the poetry of John Berryman. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/80588

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

9. Metel, Sonia. Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology.

Degree: School of Chemistry. Discipline of Chemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/80589

► This PhD Thesis addresses a comprehensive study on the application of wet-chemistry methods to the preparation of layered nanostructured materials; namely 2-dimensional Mg-Al and Ni-Fe… (more)

▼ This PhD Thesis addresses a comprehensive study on the application of wet-chemistry methods to the preparation of layered nanostructured materials; namely 2-dimensional Mg-Al and Ni-Fe layered double hydroxides and 1-dimensional layered amine-templated gallium chalcogenides. The size and the shape of the obtained materials were tailored by suitably choosing the reaction conditions and were subsequently tested in selected applications. The wet-chemistry techniques used in this Thesis relied on the versatility of commonly used approaches, such as hydrothermal and colloidal processes, with simple modifications of the reaction and post-treatment conditions, which led to the formation of nanoparticles with defined morphology and composition. Mg-Al layered double hydroxides were produced in the form of platelets with two different size ranges: 20-250 nm and 2-3 μm. The flakes with diameter below 50 nm were tested as https://tcdlocalportal.tcd.ie/pls/webapps/cerif.cerif_launcher.mainplasmid-DNA delivery agents, while the bigger flakes (2-3 μm), in their exfoliated form, are proposed as catalysts. Also, ion-exchange was carried out to minimize the interlayer interactions and facilitate their further exfoliation. On the other hand, Ni-Fe layered double hydroxides in the form of flower-like particles and platelet-like hexagons with high crystallinity were synthesized by the use of different capping agents. Both nanomaterials were tested as electrocatalysts in water splitting reaction showing promising results. Finally, amine-templated gallium chalcogenide (sulfur and selenium) nanotubes were prepared by a heating-up method. Both nanomaterials presented a hollow tubular structure with lengths up to 500 nm and 2 μm for sulfur and selenium derivative, respectively. The long-chain amines acted as a template to produce a structure composed of alternating layers of amines and polymeric gallium chalcogenide. Preliminary tests of these compounds as active materials for lithium ion batteries anodes showed their potential in energy storage. In summary, the versatility of wet-chemistry methods was explored to synthesize several layered nanomaterials with a controlled morphology. The obtained nanostructures showed promising behaviour in biological application (Mg-Al layered double hydroxide), water splitting (Ni-Fe layered double hydroxide) and energy storage (AtGaS/Se nanotubes). Advisors/Committee Members: Nicolosi, Valeria.

Subjects/Keywords: wet-chemistry; layered nanomaterials

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APA (6^th Edition):

Metel, S. (2017). Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/80589

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Metel, Sonia. “Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/80589.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Metel, Sonia. “Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology.” 2017. Web. 27 Feb 2020.

Vancouver:

Metel S. Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/80589.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Metel S. Wet-chemistry synthesis and characterization of layered nanomaterials with tailored morphology. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/80589

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

10. O'REILLY, KLARA-MAEVE. Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961.

Degree: School of Lang, Lit. & Cultural Studies. Discipline of Russian, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81682

► The collectivisation of the East German and Polish agriculture in the 1950s and 1960s stands at the centre of this thesis. The diverging experiences of… (more)

▼ The collectivisation of the East German and Polish agriculture in the 1950s and 1960s stands at the centre of this thesis. The diverging experiences of collectivisation in East Germany and Poland are investigated through contemporary party reports and present-day memories. The thesis aims to open new perspectives on the history of collectivisation in both countries by studying two hitherto neglected aspects: the every-day, standardised negotiation of popular opinion on the farms and the present-day memories of the period. Collectivisation in a transnational and comparative framework has so far only been rarely studies. Most work concentrates on the political and economic history of the policy. Contemporary memories of collectivisation also remain understudied while no attempt at placing (the memories of) collectivisation in the post-Communist discourse in central and eastern Europe has been undertaken so far. This PhD thesis fills this gap in the academic literature by combining the analysis of memories of collectivisation with the close reading of contemporary party and mood reports. On the collective farms, the opinions of peasants on socialist agriculture were based on local and economic circumstances which eventually condensed into a mosaic of personal attitudes which were context-bound and diverse. Saxon and Lower Silesian villagers and functionaries were heteroglossic and constantly engaged in the expression of statements whose meanings were similarly pluralist and context-sensitive. The most profound difference between the Saxon and Lower Silesian interviews lies in the relative position afforded to memories of collectivisation. In the Lower Silesian memories, experiences of collective farming do not occupy a prominent position and could be described as already transformed into historical knowledge. By contrast, the Saxon experiences of collectivised agriculture constitute an integral part in the autobiographies of the speakers. Advisors/Committee Members: Apor, Balazs.

Subjects/Keywords: Collectivisation; GDR; PRL; popular opinion; memory studies

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APA (6^th Edition):

O'REILLY, K. (2017). Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81682

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'REILLY, KLARA-MAEVE. “Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81682.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'REILLY, KLARA-MAEVE. “Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961.” 2017. Web. 27 Feb 2020.

Vancouver:

O'REILLY K. Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81682.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'REILLY K. Perspectives of collectivisation: Popular opinion and memory in saxony and lower silesia, 1948-1961. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81682

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

11. MEEHAN, ALAN. The SPARQL usage for mapping maintenance and reuse methodology.

Degree: School of Computer Science & Statistics. Discipline of Computer Science, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81715

► This thesis presents the SPARQL Usage for Mapping Maintenance and Reuse (SUMMR) methodology, which is for the support of performing maintenance and reuse of Linked… (more)

▼ This thesis presents the SPARQL Usage for Mapping Maintenance and Reuse (SUMMR) methodology, which is for the support of performing maintenance and reuse of Linked Data mappings. The providers of Linked Data datasets have made a great effort in recent years to publish more Linked Data on the web. These datasets cover a wide range of knowledge domains. For some datasets, their knowledge domains overlap. Due to the de-centralised nature of their development, ownership and management they use heterogeneous vocabularies. This leads to diversity of vocabulary term representations and data instance representations for overlapping terms and instances. Mappings can be used to overcome these heterogeneities, but the creation of new mappings can be a difficult and time consuming task. Therefore, reusing existing mappings, to aid in the creation of new mappings becomes appealing to dataset maintainers. In addition datasets can change over time. These changes can effect existing mappings that reference the changed dataset, causing the mappings to become invalid and no longer produce correct results. Mapping maintenance is concerned with the discovery and repair of invalid mappings and this is also a difficult and time consuming task. Through a systematic literature review, modelling and evaluation, the SUMMR methodology unifies both mapping maintenance and mapping reuse, through identifying use cases from both and combining them together, along with specific tasks, into a common methodology. SUMMR provides standard SPARQL query templates to perform maintenance and reuse use cases and tasks over RDF-based mapping representations and datasets. SUMMR provides a specialised mapping representation ? named the SPARQL Centric Mapping Representation (SCMR). SCMR is designed to represent two categories of ontology mappings (i) those used to transform data described from one Linked Data vocabulary into another and (ii) interlinks between semantically similar instances in Linked Data datasets. The SCMR represents these categories of mappings with sufficient detail to maximise support for SUMMR templates. However, SUMMR can be used with alternative RDF-based mapping representations. The SUMMR methodology has been evaluated through three lab-based experiments and a case study which involved maintenance of interlink category mappings in the DBpedia dataset. The lab-based experiments provide evidence that SUMMR templates can perform all mapping maintenance and reuse tasks over mappings represented in vi SCMR. An additional lab-based experiment provides evidence the SCMR is sufficiently expressive for representing ontology mappings which are concerned with the transformation of data from one vocabulary to another. The case study evaluation was performed to evaluate the usefulness of SUMMR in a real world Linked Data dataset management situation. SUMMR was applied to the interlink management process of the DBpedia dataset, through an open-source software tool - named the SUMMR Interlink Validation Tool, to provide SUMMR-based invalid interlink… Advisors/Committee Members: O'Sullivan, Declan.

Subjects/Keywords: Mapping Reuse; Mapping Maintenace; Linked Data; SPARQL

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APA (6^th Edition):

MEEHAN, A. (2017). The SPARQL usage for mapping maintenance and reuse methodology. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81715

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MEEHAN, ALAN. “The SPARQL usage for mapping maintenance and reuse methodology.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81715.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MEEHAN, ALAN. “The SPARQL usage for mapping maintenance and reuse methodology.” 2017. Web. 27 Feb 2020.

Vancouver:

MEEHAN A. The SPARQL usage for mapping maintenance and reuse methodology. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81715.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MEEHAN A. The SPARQL usage for mapping maintenance and reuse methodology. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81715

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Trieu, Jennifer. Food and Power in Roald Dahl's Children's Fiction.

Degree: School of English. Discipline of English, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81722

► Food and Power in Roald Dahl's Children's Fiction Jennifer Trieu Trinity College Dublin 2017 Abstract This thesis examines the representation of food and power in… (more)

Subjects/Keywords: Children's Literature; Food; Literary Theory; British Food History; Power; Children; Roald Dahl

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APA (6^th Edition):

Trieu, J. (2017). Food and Power in Roald Dahl's Children's Fiction. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81722

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Trieu, Jennifer. “Food and Power in Roald Dahl's Children's Fiction.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81722.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Trieu, Jennifer. “Food and Power in Roald Dahl's Children's Fiction.” 2017. Web. 27 Feb 2020.

Vancouver:

Trieu J. Food and Power in Roald Dahl's Children's Fiction. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81722.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Trieu J. Food and Power in Roald Dahl's Children's Fiction. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81722

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

13. Vigne, Samuel. As good as gold? About the financial implications of gold and silver.

Degree: School of Business. Discipline of Business & Administrative Studies, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81710

► International currency or production asset? Safe haven or classical commodity? This thesis offers insights into the financial implications of gold and silver by focusing on… (more)

Subjects/Keywords: Gold; Silver; Precious Metals; Inflation; Finance

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APA (6^th Edition):

Vigne, S. (2017). As good as gold? About the financial implications of gold and silver. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81710

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vigne, Samuel. “As good as gold? About the financial implications of gold and silver.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81710.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vigne, Samuel. “As good as gold? About the financial implications of gold and silver.” 2017. Web. 27 Feb 2020.

Vancouver:

Vigne S. As good as gold? About the financial implications of gold and silver. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81710.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vigne S. As good as gold? About the financial implications of gold and silver. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81710

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. GLEESON, LAURA ELIZABETH. Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection.

Degree: School of Medicine. Discipline of Clinical Medicine, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81723

► Tuberculosis (TB) is the leading infectious disease killer in the world, alongside HIV. Our understanding of the complex host immune response to Mycobacterium tuberculosis (Mtb)… (more)

▼ Tuberculosis (TB) is the leading infectious disease killer in the world, alongside HIV. Our understanding of the complex host immune response to Mycobacterium tuberculosis (Mtb) remains incomplete, but varied clinical outcomes of infection seen in humans (ranging from death to complete asymptomatic clearance of the bug) suggest that understanding host defence mechanisms may provide new insights and novel approaches to vaccine and treatment development. Integral to the host immune response to infection is the tissue-resident alveolar macrophage (AM), capable of early eradication of the bacillus but, conversely, vulnerable to subversion by the bacillus to be used as a nidus for survival and replication. Specifically, the pro-inflammatory cytokine Interleukin-1? (IL-1?) is essential for its mycobactericidal activity. Recent work in the burgeoning field of immunometabolism has linked TLR-induced changes in intracellular macrophage glucose metabolism ? namely, a shift towards aerobic glycolysis, known as the Warburg effect ? to production of IL-1?. Thus, in this body of work we investigate the metabolic impact of Mtb infection on human macrophage glucose metabolism and examine downstream functional effects of infection-induced metabolic alterations. The results presented in this body of work offer new insights into the metabolic characteristics of primary human monocyte-derived macrophages (MDM) and primary human AM. We demonstrate infection-induced glycolytic reprogramming in human and murine macrophages, mediated through TLR2/6 signalling. We find glycolytic reprogramming to be essential for optimal production of IL1B mRNA at a transcriptional level, with consequent secretion of mature IL-1?. This glycolysis-driven increase in IL-1? leads to upregulation of the eicosanoid Prostaglandin E2 (PGE2) and suppression of the anti-inflammatory cytokine Interleukin-10 (IL-10), with ultimate enhancement of macrophage mycobactericidal activity in both human and murine macrophages. We further demonstrate a similar requirement for glycolytic reprogramming in Salmonella typhimurium-infected murine macrophages. Pharmacological augmentation of glycolysis using meclizine dihydrochloride enhanced early bacillary clearance by human MDM, suggesting this newly delineated pathway of host defence may warrant exploration in the search for host-directed therapies for TB disease. Finally, we demonstrate reduced baseline metabolic activity and reduced metabolic reserves in macrophages exposed to cigarette smoke. Smoke-exposed macrophages had an attenuated metabolic response to Mtb infection, concurrent with impaired production of IL-1? and PGE2. This work demonstrates for the first time a functional role for glycolytic reprogramming in the context of host defence. This novel mechanism of the anti-mycobacterial macrophage response may be targeted for the development of new therapies and vaccines to combat this global pathogen, particularly given our observation of pharmacological manipulation of glycolytic metabolism enhancing macrophage… Advisors/Committee Members: Joseph m b, Keane.

Subjects/Keywords: Tuberculosis; Immunometabolism; Macrophage; Host defence; Glycolytic reprogramming

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APA (6^th Edition):

GLEESON, L. E. (2017). Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81723

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

GLEESON, LAURA ELIZABETH. “Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81723.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

GLEESON, LAURA ELIZABETH. “Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection.” 2017. Web. 27 Feb 2020.

Vancouver:

GLEESON LE. Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81723.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

GLEESON LE. Macrophage immunometabolism in the host response to Mycobacterium tuberculosis infection. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81723

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

15. Munshi, Reema Mohammad. Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities.

Degree: School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81724

► Uncertainty remains concerning pharmacokinetics (PK) of antimicrobials in critically ill patients due to the scarcity of data and the variable physiology of the patient cohort.… (more)

▼ Uncertainty remains concerning pharmacokinetics (PK) of antimicrobials in critically ill patients due to the scarcity of data and the variable physiology of the patient cohort. This project incorporates two distinct aims. The first aim was to describe the population PK estimates and the influence of patient covariates on PK of vancomycin following intermittent infusion in critically ill patients receiving continuous venovenous hemodiafiltration (CVVHDF), and on different anticoagulant modalities. Whereas, the second aim was to explore the potential for automatic data extraction from the electronic health record (EHR) for population PK analysis. Vancomycin dose and concentration data (peak, trough) were collected retrospectively from 31 critically ill patients (n= 280 levels). A one-compartment model was used to describe the vancomycin concentration-time profiles, using Pmetrics software. A base structural model was developed and covariates assessed for inclusion in PK models were as follows: Dialysis status was categorised as 1) dialysis with regional citrate anticoagulation (RCA) (60 levels) 2) dialysis not using RCA (non-citrate) (120 levels) or 3) no dialysis (44 levels). Continuous covariates were: cumulative fluid balance (FB), effluent flow rate (EFR), blood flow rate, body weight, albumin concentration (Alb) and age. Considering the high inherent variability in this patient cohort, the structural base models were reasonable using both clearance (CL) with volume of distribution (V) and elimination rate constant (Ke) with V, even without addition of covariates, with observed vs. predicted (o-p) R2 values of 0.51 and 0.81 for population and posterior individual predicted models respectively. The mean ? SD of total vancomycin PK estimates were: CL: 2.16 ? 0.57 L/h, V: 80.65 ? 22.65 L, and Ke: 0.03 ? 0.01 h. The best population predicted models (o-p R2= 0.59) included FB as a continuous covariate applied to the V parameter and Alb applied to the Kei parameter (using the inverse approach). Interestingly, there was a suggested improvement in the population model of the RCA modality group over the non-dialysis cohort, with o-p R2 of 0.86 and 0.28, respectively (o-p R2 non-citrate dialysis= 0.58). The less variable PK estimates in the RCA group model suggests that initial vancomycin dosing in this type of patient might be more straightforward than in the other anticoagulant categories, due to the homogeneity of patients in the citrate group. No single covariate model using all patients provided a notable improvement simultaneously in both population predictions and posterior individual predictions. Inclusion of an intercept in the PK parameter-covariate relationship was necessary to detect significant covariate relationships with PK parameters. Furthermore, investigated automated data extraction method was potentially valuable for use in PK analysis, after further development to achieve a reliable automated extraction system. Ultimately, FB, Alb data and RCA status are suggested as covariates for further analysis with… Advisors/Committee Members: D'Arcy, Deirdre.

Subjects/Keywords: population pharmacokinetic; continuous venovenous hemodiafiltration

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APA (6^th Edition):

Munshi, R. M. (2017). Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81724

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Munshi, Reema Mohammad. “Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81724.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Munshi, Reema Mohammad. “Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities.” 2017. Web. 27 Feb 2020.

Vancouver:

Munshi RM. Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81724.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Munshi RM. Exploring population pharmacokinetic models in patients treated with vancomycin during continuous venovenous hemodiafiltration on different anticoagulant modalities. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81724

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

16. De Contreras, Catherine. A proposal for a single model of equitable estoppel.

Degree: School of Law. Discipline of Law, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81738

► The research objectives were to build a unified equitable estoppel model that simplified the irregularities in the equitable estoppels as identified in England, while consolidating… (more)

▼ The research objectives were to build a unified equitable estoppel model that simplified the irregularities in the equitable estoppels as identified in England, while consolidating the essential principles to be applied in a unified model, with a view to potentially applying the model generally. Other jurisdictions which received notable focus were Ireland and Australia, chosen respectively because of the fertile Irish ground for further development, and because the Australian approach diverges significantly from that in England. The model sought to simplify and consolidate equitable estoppel, and to make it generally applicable. The focus on English cases throughout the thesis served to highlight some difficulties within equitable estoppel as it has developed in that jurisdiction in particular and hence identify the most confusing features of the doctrine. Two surveys were conducted, which showed four key issues: an imprecision of terminology, a perception that estoppel is a fallback claim, a possible lack of development of the doctrine, and some welcoming attitudes towards a possible unified doctrine and of fulfilling such missing development. In particular, it was questioned whether these concerns were more broadly indicative of the existence of doctrinal inconsistencies, and whether a unified model could be proposed which would address those inconsistencies. A model was incrementally built by addressing some wider doctrinal concerns in the English law. A conceptual sketch found that there is space for welcome development of a doctrine reddressing detrimental reliance, and that this concept is associated with equitable estoppel. On the basis of the views of McFarlane and Liew respectively, it was, first, found that a possible unified equitable estoppel would be in the nature of a liability, and, it was, secondly, suggested that it would give rise to a reflective remedy in the shape of a minimum equity. Meanings of unconscionability, a concept in equitable estoppel which has led to a great deal of commentary, were separated and analysed. It was found that unconscionabilty can mean, first, the jurisdiction in the sense of a basis for the existence of equitable estoppel in the first place; secondly, the context in which v the reliance takes place; thirdly, the justifiability of the reliance; fourthly, whether it is unconscionable to move to an inconsistent position; fifthly, whether the court ought to grant a remedy; and, finally, what parameters aid the court in shaping the remedy. Meanwhile, several inconsistencies were found in the processes of shaping a liability and a remedy in English law. English law and doctrinal commentary generally prefers not to view some estoppels as giving rise to a cause of action, and not to accept a unified doctrine: contrasting views were put forward dealing with both matters. The liability-finding process itself was found to have a simpler basis than it currently has, and the remedy-finding process tending towards the award of an expectation was compared with similar processes in… Advisors/Committee Members: Biehler, Hilary.

Subjects/Keywords: Estoppel; Private law; Law of obligations; Promissory estoppel; Proprietary estoppel; Equity

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APA (6^th Edition):

De Contreras, C. (2017). A proposal for a single model of equitable estoppel. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81738

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

De Contreras, Catherine. “A proposal for a single model of equitable estoppel.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81738.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

De Contreras, Catherine. “A proposal for a single model of equitable estoppel.” 2017. Web. 27 Feb 2020.

Vancouver:

De Contreras C. A proposal for a single model of equitable estoppel. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81738.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

De Contreras C. A proposal for a single model of equitable estoppel. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81738

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

17. MILLS, SHAUN. The effects of residual stress on the material characterisation of individual nanowires.

Degree: School of Chemistry. Discipline of Chemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81728

► Many of the techniques currently used to measure the mechanical properties of individual nanowires make the assumption that initially the nanowires are in a zero-stress… (more)

Subjects/Keywords: nanowires; residual stress; Young's modulus

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APA (6^th Edition):

MILLS, S. (2017). The effects of residual stress on the material characterisation of individual nanowires. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81728

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MILLS, SHAUN. “The effects of residual stress on the material characterisation of individual nanowires.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81728.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MILLS, SHAUN. “The effects of residual stress on the material characterisation of individual nanowires.” 2017. Web. 27 Feb 2020.

Vancouver:

MILLS S. The effects of residual stress on the material characterisation of individual nanowires. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81728.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MILLS S. The effects of residual stress on the material characterisation of individual nanowires. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81728

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Barry-Reidy, Anne. Regulation of bovine beta-defensin expression.

Degree: School of Biochemistry & Immunology. Discipline of Biochemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81726

► Beta-defensins are a class of host defence peptides with antibacterial, antiviral and immunomodulatory roles. The bovine genome contains up to 57 putative beta-defensin genes in… (more)

▼ Beta-defensins are a class of host defence peptides with antibacterial, antiviral and immunomodulatory roles. The bovine genome contains up to 57 putative beta-defensin genes in four syntenic clusters on different chromosomes. The regulation of expression of these pleiotropic molecules is still poorly explored. As beta-defensins are involved in bovine fertility, the overall aim of this project was to investigate the regulation of expression of beta-defensins in this context. We have bioinformatically analysed the proximal promoter regions of chromosome 13 beta-defensin genes from the bovine and other mammals to identify potential regulators of gene transcription for further investigation. Transcription factor binding site over-representation analysis of a beta-defensin cluster which is highly expressed in the male reproductive tract indicates enrichment of DNA binding sites for transcription factors important in regulating gene expression at this site. These include androgen receptor, glucocorticoid receptor and retinoic acid receptor. Alignment of over 300kb of this beta-defensin gene region from five distantly-related mammals highlighted three putative intergenic enhancers within the cluster. A candidate enhancer proximal to DEFB126, which is associated with male fertility, contains binding sites for androgen receptor and AP-2alpha, a chromatin-opening transcription factor known to co-operate with androgen receptor in the murine epididymis. We hypothesise that these potential enhancers may act as distal regulatory elements to control expression of one or more male reproductive tract-specific beta-defensins. Beta-defensin 3, encoded by the gene DEFB103, has been attributed roles in direct antimicrobial defence, immunomodulation and wound healing. As this gene is associated with an inflammatory gene signature in the post-partum bovine uterus, in which endometritis is both prevalent and economically important, we were interested in identifying stimuli driving DEFB103 expression. Application of our transcription factor binding site over-representation approach to the promoters of DEFB103 orthologs indicates AP-1 regulation of this gene at the transcriptional level. AP-1 mediates the response to a number of inflammatory stimuli and regulates DEFB103 in some human cell types. Therefore we investigated inflammation-driven beta-defensin expression in a bovine reproductive tract-derived primary cell culture model. Cultured primary endometrial stromal cells isolated from reproductive tracts of recently slaughtered cows constitutively express DEFB103. A primer set targeting the ruminant expansion of DEFB4A (eDEFB4A), consisting of eight chromosome 27 beta-defensins with high sequence similarity, revealed expression of at least one of these genes in stromal cells. As IL-1beta and IL-17A are implicated as drivers of human beta-defensin expression, they were used to stimulate bovine endometrial stromal cells. IL-1beta upregulated expression of DEFB103 and eDEFB4A. IL-17A also upregulates DEFB103. Upregulation of beta-defensins… Advisors/Committee Members: O'Farrelly, Cliona, Teagasc.

Subjects/Keywords: bovine immunology; beta-defensins; innate immunity; antimicrobial peptides

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APA (6^th Edition):

Barry-Reidy, A. (2017). Regulation of bovine beta-defensin expression. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81726

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Barry-Reidy, Anne. “Regulation of bovine beta-defensin expression.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81726.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Barry-Reidy, Anne. “Regulation of bovine beta-defensin expression.” 2017. Web. 27 Feb 2020.

Vancouver:

Barry-Reidy A. Regulation of bovine beta-defensin expression. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81726.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Barry-Reidy A. Regulation of bovine beta-defensin expression. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81726

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. Xu, Shixiong. Data layout oriented compilation techniques in vectorization for multi-/many-cores.

Degree: School of Computer Science & Statistics. Discipline of Computer Science, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81727

► Single instruction, multiple data (SIMD) architectures are widely adopted in both general-purpose processors and graphic processing units for exploiting data-level parallelism. It is tedious and… (more)

▼ Single instruction, multiple data (SIMD) architectures are widely adopted in both general-purpose processors and graphic processing units for exploiting data-level parallelism. It is tedious and error-prone for programmers to write high performance code to utilize SIMD execution units on both platforms. Therefore, users often rely on automatic code generation techniques in compilers. However, it is not trivial for compilers to generate high performance code without considering the data layout of the data used in the computation. Data layout determines data access patterns, and in turn have a great impact on the memory performance of the automatically generated code for both CPUs and GPUs. In this thesis, we demonstrate several data layout oriented compilation techniques for efficient vectorization. We put forward semi-automatic data layout transformation to help users to easily change their program, and exploit the best possible data layout in terms of vectorization. Our proposed vectorization based on hyper loop parallelism provides a way to take advantage the relationship between data layout and computation structure. The experimental results demonstrated that this vectorization technique can yield significant performance gain. In addition, we show that this technique is of great use to boost the memory performance on CUDA GPUs. We also present pioneering work that uses loop vectorization techniques to handle nested thread-level parallelism (TLP) on CUDA GPUs. As loop vectorization prioritizes vectorizing loops with contiguous data accesses, it is of great help to achieve an efficient mapping strategy for nested TLP on CUDA GPUs. Our new bitslice vector computing for customizable arithmetic precision on general-purpose processors with SIMD extensions not only breaks the limit of hardware arithmetic precision but also achieves great performance. It also shows the great power of logic optimization widely used in hardware synthesis in optimizing C/C++ code with a large amount of logic operations. Advisors/Committee Members: Gregg, David.

Subjects/Keywords: compiler; data layout; vectorization; bitslice; source-to-source transformation; single instruction multiple data (SIMD)

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Xu, S. (2017). Data layout oriented compilation techniques in vectorization for multi-/many-cores. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81727

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Xu, Shixiong. “Data layout oriented compilation techniques in vectorization for multi-/many-cores.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81727.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Xu, Shixiong. “Data layout oriented compilation techniques in vectorization for multi-/many-cores.” 2017. Web. 27 Feb 2020.

Vancouver:

Xu S. Data layout oriented compilation techniques in vectorization for multi-/many-cores. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81727.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Xu S. Data layout oriented compilation techniques in vectorization for multi-/many-cores. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81727

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. MURRAY, PAUL RAPHAEL. The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance.

Degree: School of Law. Discipline of Law, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81740

► The overall research question addressed in this thesis is the data privacy/national security balancing paradigm, and the contrasting ways in which this operates in Europe… (more)

Subjects/Keywords: Telecommunications Data Retention; State Surveillance; Privacy Rights; Balancing Paradigm; Transatlantic Contrasts; State Security

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APA (6^th Edition):

MURRAY, P. R. (2017). The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81740

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MURRAY, PAUL RAPHAEL. “The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81740.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MURRAY, PAUL RAPHAEL. “The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance.” 2017. Web. 27 Feb 2020.

Vancouver:

MURRAY PR. The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81740.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MURRAY PR. The data privacy / national security balancing paradigm as applied in the USA and Europe: Achieving an acceptable balance. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81740

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. ZEN, FEDERICO. Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions.

Degree: School of Chemistry. Discipline of Chemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81741

► Carbon materials and nanomaterials are of great interest for biological applications such as implantable apparatus and nanoparticle vectors. In particular, amorphous carbon is extensively used… (more)

Subjects/Keywords: amorphous carbon; protein adsorption; antifouling; quartz crystal microbalance; localized surface plasmon resonance; biomaterial

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APA (6^th Edition):

ZEN, F. (2017). Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81741

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

ZEN, FEDERICO. “Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81741.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

ZEN, FEDERICO. “Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions.” 2017. Web. 27 Feb 2020.

Vancouver:

ZEN F. Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81741.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

ZEN F. Controlling the carbon-bio interface: ex-situ and in-situ studies of fundamental biomolecule – carbon reactions. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81741

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

22. Vaisi, Salahadin. Thermal energy modelling, benchmarking and mapping for university campus buildings.

Degree: School of Engineering. Disc of Civil Structural & Environmental Eng, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81742

► According to the Chartered Institution of Building Services Engineering, CIBSE TM46:2008 University Campus benchmark, a college building needs 240 kWh/m2 of thermal energy and proportionally… (more)

▼ According to the Chartered Institution of Building Services Engineering, CIBSE TM46:2008 University Campus benchmark, a college building needs 240 kWh/m2 of thermal energy and proportionally produces 45.6kg CO2 per annum. As heat consumption largely depends on the ambient temperature, this fixed-annual benchmark is not suitable because it does not deliver any difference between summer and winter. Firstly, the current research analysed the accuracy of the CIBSE TM46 ?University Campus? benchmark against the thermal consumption values presented in Display Energy Certificates (DECs). The DECs of 52 college buildings belonging to four universities in Dublin were assessed and based on the 46% discrepancy between the median of analysed samples and the CIBSE UC (University Campus) benchmark, a new benchmark of 130 kWh/m2/yr was recommended. This new benchmark is 110 kWh/m2/yr lower than the current benchmark which is a substantial improvement. The UC revised benchmark (UCrb, 130 kWh/m2/yr) was validated using Descriptive Statistics (DS). It has been found that the UCrb is a precise description of an up-to-date typical performance of college buildings in Dublin. The benefits of UCrb in terms of fossil energy saving and reduction of CO2 emissions were calibrated and the results interpreted based on CIBSE UC benchmark and DEC values. Considering the large size of college buildings, applying UCrb could decrease the fossil consumption in Irish universities dramatically because the UCrb is approximately half of the current benchmark. Secondly, Monthly Thermal Energy Models (MTEMs) which took into account the variations of heat demand during a year were generated using five key factors including mixed use approach, UCrb, activities area, heating degree days, and typical operation hours of heating systems. Two methods for generating the monthly heat models were presented based on the mixed use activities and Display Energy Certificates (DECs). Unlike many studies on energy modelling and benchmarking assuming buildings are single use, in the presented methodology the impact of mixed activities on heat consumption was considered. The results of MTEMs were compared with the CIBSE TM46 methodology and a significant development was obtained. When the absolute error of CIBSE UC benchmark for heat estimation was nearly 98% in summer months, the errors of MTEMs were less than 21%. Moreover, the results of R-squared analyses confirmed the accuracy of models. Thirdly, the methodology of MTEMs was developed and Monthly Thermal Energy Benchmarks (MTEBs) were generated for the first time in the area. Comparing the fixed-annual CIBSE UC benchmark of 240 kWh/m2/yr, MTEBs altered from 21 kWh/m2 in January to 1 and nearly zero kWh/m2 in June and July respectively. Comparing the current CIBSE TM46 university campus benchmark, MTEBs are very sensitive and compatible with the real conditions. They also share more information than an annual index. The MTEMs and MTEBs were used to generate detailed heat energy maps which showed the thermal energy… Advisors/Committee Members: McCormack, Sarah.

Subjects/Keywords: Energy modelling; Energy benchmarks; Energy estimation; Thermal energy efficiency

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APA (6^th Edition):

Vaisi, S. (2017). Thermal energy modelling, benchmarking and mapping for university campus buildings. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81742

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vaisi, Salahadin. “Thermal energy modelling, benchmarking and mapping for university campus buildings.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81742.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vaisi, Salahadin. “Thermal energy modelling, benchmarking and mapping for university campus buildings.” 2017. Web. 27 Feb 2020.

Vancouver:

Vaisi S. Thermal energy modelling, benchmarking and mapping for university campus buildings. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81742.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vaisi S. Thermal energy modelling, benchmarking and mapping for university campus buildings. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81742

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

23. KWASNIEWSKA, KAMILA. Control of floral meristem activity in the model plant Arabidopsis thaliana.

Degree: School of Genetics & Microbiology. Discipline of Genetics, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81745

► Over the past 30 years, the flower development has been one of the main model to study the genetic control of organogenesis in higher plants.… (more)

▼ Over the past 30 years, the flower development has been one of the main model to study the genetic control of organogenesis in higher plants. The work on Arabidopsis thaliana has led to the proposal of the ABC model of flower development. This model states the interaction of three classes of the genes that encode transcription factors specifying the four types of organs in the flower, i.e, sepals, petals, stamens and carpels. While the activities of these master regulators have been extensively characterized in recent years, comparatively little is known about the functions of the target genes of these regulators. One of the genes that is acting downstream of AGAMOUS (AG) ? the transcription factor that specifies the formation of a carpel, is KNUCKLES (KNU). It has been reported that KNU is directly activated by AG and is believed to be a repressor of WUSCHEL (WUS) activity in the meristematic cells. To fully understand functions of KNU in the stem cells, several transgenic lines were generated. I used approaches allowing for knockdown of KNU functions in different regions of stem cells. I showed, that KNU is expressed earlier in the flower development and interacts with the gene regulating the size of meristem. Although, the functions that KNU plays in flower development were described over a decade ago, its additional roles have not been proposed. The genome-wide binding data of KNU and the gene expression changes upon perturbation of KNU functions are still missing. To address this knowledge gap, the main focus of this thesis was on the characterization of the role of KNUCKLES (KNU) on a genome-wide scale. Using genomic technologies, I showed that KNU directly regulates sets of genes that act in the meristem development and maintenance. I also presented evidence that KNU regulates key factors that suppress or activate the trichome formation. I further showed that KNU is involved in regulation of the hormone metabolism and balancing their levels. In the second part of this thesis, the dynamic distribution of epigenetic marks during early stages of flower development was investigated. The epigenetics is often defined as changes that are not caused by the modification in the DNA but instead by the DNA methylation or post-translational modification of the histones. These changes have a substantial role in the processes that are involved in the formation and development of a flower. To better understand the mechanisms underlying the successful flower development, I used genome-wide approaches allowing for identification of interactions between the flower master regulator APETALA1 (AP1) and the epigenome. For that, the specific gene regions that are repressed or activated by the selected methylation marks were analyzed at different stages of flower development that is triggered by AP1. This work yielded in preliminary characterization of the interplay between the transcriptional regulation and the epigenetic mechanisms during the flower formation. Advisors/Committee Members: Wellmer, Frank.

Subjects/Keywords: Arabidopsis thaliana; meristem; flower development

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APA (6^th Edition):

KWASNIEWSKA, K. (2017). Control of floral meristem activity in the model plant Arabidopsis thaliana. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81745

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

KWASNIEWSKA, KAMILA. “Control of floral meristem activity in the model plant Arabidopsis thaliana.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81745.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

KWASNIEWSKA, KAMILA. “Control of floral meristem activity in the model plant Arabidopsis thaliana.” 2017. Web. 27 Feb 2020.

Vancouver:

KWASNIEWSKA K. Control of floral meristem activity in the model plant Arabidopsis thaliana. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81745.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

KWASNIEWSKA K. Control of floral meristem activity in the model plant Arabidopsis thaliana. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81745

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

24. O'NEILL, TERENCE STEPHEN. Supervisee transfer of learning in psychotherapy supervision.

Degree: School of Psychology. Discipline of Psychology, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81754

► Aim: Clinical supervision is a well established means of facilitating supervisee learning and transfer of learning is explicitly linked to learning. Within the clinical supervision… (more)

▼ Aim: Clinical supervision is a well established means of facilitating supervisee learning and transfer of learning is explicitly linked to learning. Within the clinical supervision literature, there is an absence of research on supervisee transfer of learning. The purpose of this research project was to address the gap in the literature using a discovery-oriented research approach which involved the design of two studies. Method: Study 1 was an analogue case study using a simulated supervisory triad of supervisor, supervisee and client. The data from Study 1 were collected using Brief Structured Recall interviews which were analysed using Comprehensive Process Analysis. Data for Study 1 were also collected using the Supervisory Working Alliance Inventory (Efstation, Patton & Kardash, 1990) and the Working Alliance Inventory (Horvath & Greenberg, 1989; Tracey & Kokotowitz, 1989). Data were collected for Study 2 from semi-structured interviews with 12 supervisees with experience of transferring learning from supervision into therapy practice. The data from Study 2 were analysed using a combination of Comprehensive Process Analysis and Descriptive and Interpretative qualitative research. Research participants from both Study 1 and Study 2 also completed demographic questionnaires. Results; Supervisee learning events in supervision stem from the supervisee experiences in counselling and supervisee learning in supervision is facilitated through good supervisory working alliances. Factors influencing supervisee transfer of learning from supervision include the timing of supervision sessions; supervisee levels of motivation; the strength of the working alliance in therapy; possibilities for transfer in counselling sessions; supervisee ability to generalise learning into counselling sessions; supervisee ability to improvise their learning in counselling sessions. Conclusion; Supervisee learning takes place in both supervision and counselling and these settings can be considered as sites for invention and innovation, where supervisee learning is constructed, reorganised and transformed in a co-creative process. Supervisee learning is then transferred from supervision into counselling and vice versa. The supervisee learning and transfer process can be imagined as a continuous loop linking supervision and counselling in a reciprocal relationship. Transfer of learning is identified as a dynamic process rather than a simple pattern of learn-it-here and apply-it-there. As part of this dynamic process the client contributes to supervisee learning and the transfer of learning from supervision. This has a consequential impact on the client?s own learning and insights which are recognised as positive outcomes of the counselling process. Implications and recommendations from this research for supervisors, supervisees, supervision theory, training and research in supervision were also identified. Advisors/Committee Members: Creaner, Mary.

Subjects/Keywords: Transfer of learning; Clinical supervision

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APA (6^th Edition):

O'NEILL, T. S. (2017). Supervisee transfer of learning in psychotherapy supervision. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81754

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'NEILL, TERENCE STEPHEN. “Supervisee transfer of learning in psychotherapy supervision.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81754.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'NEILL, TERENCE STEPHEN. “Supervisee transfer of learning in psychotherapy supervision.” 2017. Web. 27 Feb 2020.

Vancouver:

O'NEILL TS. Supervisee transfer of learning in psychotherapy supervision. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81754.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'NEILL TS. Supervisee transfer of learning in psychotherapy supervision. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81754

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

25. O'HANLON, NIALL. On the origins and evolution of the Revenue Rule: the quest for certainty.

Degree: School of Law. Discipline of Law, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81757

► The thesis advanced in this work is that the Revenue Rule, which stipulates that whilst forum courts may recognise a foreign tax law, they will… (more)

▼ The thesis advanced in this work is that the Revenue Rule, which stipulates that whilst forum courts may recognise a foreign tax law, they will not enforce it, does not meet the criteria of certainty. Uncertainties arise in relation to the origins, taxonomy and extent of the Rule, to what constitutes a revenue law, to the distinction between revenue and penal laws, to the supposed distinction between recognition and indirect enforcement of foreign revenue law and to what constitutes the rationale for the Rule. The thesis begins with a modern statement of the Revenue Rule and a review, from a public international law perspective, of the nature and extent of a state?s power to tax. Problems of classification are examined; in particular, the uncertainties surrounding what constitutes a revenue law and the appropriate classification, as between penal and revenue, of the criminal provisions that are invariably contained in taxation legislation. The uncertainties attaching to the precise origin of the Revenue Rule are identified and a conceptual framework is developed and applied in analysing the early decisions relating to the Rule. The fundamental difficulties associated with the recognition/enforcement dichotomy are examined and an alternative classification is advanced. The relationships between the act of state doctrine, the Revenue Rule and the doctrine of state or sovereign immunity, are considered, as are the uncertainties attaching to the taxonomy of the Rule. The hypothesis that the Revenue Rule constitutes a part of public, rather than private, international law is evaluated and the emerging confluence of these two areas of the law is noted. In light of the assertion that, a departure from the Revenue Rule constitutes a derogation from sovereignty, the converse hypothesis, that in circumstances of constrained sovereignty departures from the Rule will be observable, is formulated and tested. Drawing on finance theory, this hypothesis is advanced in two forms; a strong form ? constrained sovereignty will result in a departure from the Revenue Rule, and; a weak form ? constrained sovereignty may result in a departure from the Rule. The various justifications for the Revenue Rule are examined, including the contention that the self-interest of the forum provides the most compelling rationale for the existence and persistence of the Rule. The development of the doctrine of functional enforcement, in the United States, is examined and the possibility of a trans-Atlantic divide, given recent UK and European Court of Justice decisions, is considered. The degree to which it is possible to avoid the Revenue Rule, by seeking in personam and in rem remedies, is explored, and a new category, ad informandum, is proposed. The uncertainties relating to the extent to which the courts are willing to modify the operation of the Revenue Rule to protect the interests of fiduciaries is considered and the evolving application of the Rule, in the context of transnational insolvencies, is examined. The thesis concludes that,… Advisors/Committee Members: Schuster, Alexander.

Subjects/Keywords: Public International Law; The Revenue Rule; Private International Law

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APA (6^th Edition):

O'HANLON, N. (2017). On the origins and evolution of the Revenue Rule: the quest for certainty. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81757

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

O'HANLON, NIALL. “On the origins and evolution of the Revenue Rule: the quest for certainty.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81757.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

O'HANLON, NIALL. “On the origins and evolution of the Revenue Rule: the quest for certainty.” 2017. Web. 27 Feb 2020.

Vancouver:

O'HANLON N. On the origins and evolution of the Revenue Rule: the quest for certainty. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81757.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

O'HANLON N. On the origins and evolution of the Revenue Rule: the quest for certainty. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81757

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

26. MC GANN, JAMIE. Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting.

Degree: School of Computer Science & Statistics. Discipline of Computer Science, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81759

► Sedentary video gameplay is typically described as a contributing factor to poor locomotor skills (hop, skip and jump etc.) observed in the modern day child.… (more)

▼ Sedentary video gameplay is typically described as a contributing factor to poor locomotor skills (hop, skip and jump etc.) observed in the modern day child. Further, poor locomotor skills are a significant predictor of problems elsewhere including health, speech and language, behaviour and reading fluency. Conversely, with the emergence of 3D sensor interfaces (e.g. Kinect), video games now support full body, gross motor simulated interactivity. This offers an intriguing opportunity to transform a potential barrier to locomotor acquisition into a veritable training ground. This thesis is initially concerned with the design of a theoretically informed and ?principled? framework (entitled PaCMAn: Principles and Conditions for Motor Acquisition) which can be utilised to underpin video games for locomotor acquisition for use in the classroom setting. Following this, a series of adaptable games are developed to facilitate instant adaption of gaming features by a human adaptive component; the teacher. The adaptive nature of these games allows the teacher to negotiate currently existing 3D sensor limitations by adapting parameters of gameplay ?on the fly? in line with individual user needs. The teacher is also expected to deliver additional parts of the framework that the game/system cannot. Specific details relating to the role of the teacher, in terms of the deployment process, were evaluated during an initial period of action research carried out in the classroom setting. This resulted in the articulation of A Teacher Adaption and Deployment Guide. A second period of action research focused on the effectiveness of videogames for locomotor acquisition in the classroom; both from the point of view of the teacher (i.e. could teachers do all of the things asked of them in the deployment guide?) and from the point of view of the learner (i.e. did an extended period of gameplay lead to improved locomotor skills?). Quantitative findings indicate that the games outlined in this thesis supported significant improvements in user locomotor skills. Additionally, qualitative findings indicate that teachers were not only capable of deploying these games effectively but were also empowered by the meaningful role they had to play in the delivery process. Ergo, video games present as a useful platform capable of supporting and enhancing both the teaching and learning of locomotor skills in the classroom setting. Advisors/Committee Members: Conlan, Owen.

Subjects/Keywords: e-health; gross motor skills; game design; motor learning principles; exergames; elementary education; game deployment; game development

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

MC GANN, J. (2017). Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81759

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MC GANN, JAMIE. “Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81759.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MC GANN, JAMIE. “Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting.” 2017. Web. 27 Feb 2020.

Vancouver:

MC GANN J. Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81759.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MC GANN J. Hop.Skip.Jump.Games. The design, development, deployment and evaluation of video games to support locomotor acquisition in a classroom setting. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81759

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

27. ZHANG, LIN. Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials.

Degree: School of Engineering. Disc of Civil Structural & Environmental Eng, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81758

► This PhD research includes two parts, viz. experimental investigation on the undrained mechanical properties of undisturbed fibrous peat and a finite strain constitutive model within… (more)

▼ This PhD research includes two parts, viz. experimental investigation on the undrained mechanical properties of undisturbed fibrous peat and a finite strain constitutive model within a thermodynamically consistent framework based on the experimental results of the tested peat. From the laboratory investigation, nonlinear behaviour with large strain was observed from the loading-unloading tests on peat. The influence of cell pressure, strain rate, stress relaxation on the constitutive behaviour as well as strain recoveries from unloading were investigated. Relaxation tests were carried out for overstress quantification as well as to obtain the equilibrium state. The tested peat was categorised as a rate-dependent material with equilibrium hysteresis. Structural anisotropy was also investigated by testing the undisturbed vertical and horizontal specimens under the same conditions. Although in the proposed model, the structural anisotropy was not included, the experimental data provided the foundation for the future development of anisotropic constitutive models. The observed material behaviour motivated a rheological model comprising four parallel layers, each consisting of elastic, viscoelastic and elastoplastic elements. The proposed hyperviscoplastic model was derived from the entropy inequality. Each part of the model was verified against their analytical solutions. The model parameter fitting started with the rate-independent equilibrium tests, where the hyperelastoplastic model was fitted to the defined laboratory equilibrium test. Two compression-relaxation tests, carried out at different strain rates, were used for the parameter estimation of the rate-dependent hyperviscoplastic model. The hyperviscoplastic model was validated against five strain rate tests under various load cases as well as an undrained triaxial creep test. The finite strain constitutive model derived within a thermodynamically consistent framework showed its versatility in simulating peat behaviour in various load cases by a good agreement of the experimental results. Also, from the process of the deriving the hyperviscoplastic model, it is perceived that it would be easy to extend the current model with more features in a mathematically and thermomechanically consistent manner. Advisors/Committee Members: O'Kelly, Brendan, Nagel, Thomas.

Subjects/Keywords: Peat Materials; Thermodynamically Consistent; Hyperviscoplastic model; Finite strain; Undrained triaxial tests; Loading-unloading and relaxation tests

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APA (6^th Edition):

ZHANG, L. (2017). Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81758

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

ZHANG, LIN. “Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81758.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

ZHANG, LIN. “Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials.” 2017. Web. 27 Feb 2020.

Vancouver:

ZHANG L. Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81758.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

ZHANG L. Undrained Triaxial Experimental Investigations and Hyperviscoplastic Modelling of Peat Materials. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81758

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

28. BRADBERRY, SAMUEL JOHN. Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials.

Degree: School of Chemistry. Discipline of Chemistry, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81762

► This thesis describes the design, synthesis and characterisation of naphthyl-dipicolylamide (naphthyl-dpa) ligands for sensitisation of lanthanide, Ln(III), emission. Chapter 1 provides an introduction to the… (more)

▼ This thesis describes the design, synthesis and characterisation of naphthyl-dipicolylamide (naphthyl-dpa) ligands for sensitisation of lanthanide, Ln(III), emission. Chapter 1 provides an introduction to the fundamental physical and chemical properties of LnIII ions with particular focus on the photophysical properties. The features of emissive Ln(III) ions will be reviewed, an overview given to the mechanisms available to access this f-metal-centred luminescence and the key design features for ligands highlighted. This is followed by a review of current literature and the immediate prior art from the Gunnlaugsson laboratory. Chapter 2 will describe the design and synthesis of naphthyl-dpa derivatives functionalised with sulfonate groups, ensuring aqueous solubility of these ligands. A pair of enantiomeric ligands will be presented, the photophysical properties of these ligands and their complexes with Eu(III) are probed in both aqueous and organic solutions, showing total quantum yield enhancements in the aqueous environment. The self-assembly behaviours of the ligands is investigated using spectroscopy. Chiral spectroscopy is exploited to analyse the photophysical properties and self-assembly in greater depth and global stability constants determined by non-linear regression analysis.This chapter concludes in the formation of gelled soft matter at higher concentration, using insights from dynamic light scattering (DLS), isothermal titration calorimetry (ITC) and scanning electron microscopy (SEM). In Chapter 3, the extension of the naphthyl-dpa scaffold into responsive luminescent probes will be investigated. A family of chiral ligands and their complexes with Eu(III) are characterised in acetonitrile and methanol. The influence of the ligand substitution pattern and peripheral covalent structure is probed, revealing ?spectral fingerprints? and responsive behaviours in ligand- and metal-centred emissions. Self-assembly processes are probed in, showing similar processes between ligands, however differing significantly in their emission properties during self-assembly. A PET response is exploited in the development of acidity probes and one complex is calibrated in 5% methanol:water as a pH probe, showing a sensitive pH response in both ligand- and metal-centred emissions. This chapter concludes by describing the fabrication of a hydrogel-based pH sensor using Eu(III)-centred luminescence, clear spectroscopic and visual responses are demonstrated to both solution and vapour stimuli. Chapter 4 focusses on the design of molecular logic gate mimics (MLGMs) in solution and polymer gels. This example represents one of the first soft materials-based MLGMs using Ln(III) luminescence. Firstly, a brief introduction will present the fundamentals of logical analysis and the limited examples of exploiting Ln(III) luminescence. A mixed Eu(III):Tb(III) system will be discussed showing luminescence responses to H+ and F-. These responses are characterised in methanol and organogels parameterised as logic functions; both clear… Advisors/Committee Members: Gunnlaugsson, Thorfinnu.

Subjects/Keywords: lanthanide luminescence; europium; molecular logic; soft materials; hydrogel; organogel; luminescent materials

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APA (6^th Edition):

BRADBERRY, S. J. (2017). Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81762

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

BRADBERRY, SAMUEL JOHN. “Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81762.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

BRADBERRY, SAMUEL JOHN. “Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials.” 2017. Web. 27 Feb 2020.

Vancouver:

BRADBERRY SJ. Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81762.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

BRADBERRY SJ. Design and development of novel self-assembled luminescent lanthanide complexes in solution and in soft materials. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81762

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

29. MALONE, KEIRA MARY. An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers.

Degree: School of Dental Sciences. Discipline of Dental Science, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81817

► ABSTRACT Background: Approximately 30% of humans are Staphylococcus aureus nasal carriers and oro-nasal trafficking of the organisms is frequent. Carriage of S. aureus can be… (more)

▼ ABSTRACT Background: Approximately 30% of humans are Staphylococcus aureus nasal carriers and oro-nasal trafficking of the organisms is frequent. Carriage of S. aureus can be persistent or transient. Healthcare workers (HCWs) have been implicated in transmission of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) to patients. Oro-nasal colonisation prevalence data for dental HCWs is scarce. Aims and Objectives: To investigate the prevalence of transient and persistent oro-nasal colonisation by S. aureus of two groups of dental HCWs including (A) Dublin Dental University Hospital HCWs working at outreach multicentre facilities and (B) dental HCWs in general practices in four different locations, and to characterise S. aureus isolates recovered. To achieve these objectives, volunteers from each group were screened twice for S. aureus carriage over three months. Methods: Ethicial permission was granted by the Tallaght Hospital/St. James's Hospital Joint Research Ethics Committee. Nasal swabs and oral rinses were taken from 79 volunteer participants (n = 39 from group A, n = 40 from group B). Presumptive S. aureus were recovered on SaSelectTM (Bio-Rad) medium and confirmed by growth on mannitol salt agar and using the Pastorex? Staph Plus kit (Bio-Rad). Twenty-four and 35 selected isolates from separate participants from the first and second collection phases, respectively, were screened for antimicrobial resistance and virulence-associated genes by DNA microarray profiling (Alere GmbH). Results: MRSA was not detected from any of the participants. The MSSA nasal and oral carriage rate among participants during the first and second screening phases was 16.5% (13/79) and 17.7% (14/79) and 22.8% (18/79) and 21.5% (17/79), respectively. The overall S. aureus carriage rate during the first and second screening phases was 15.5%. The first phase sampling identified 13 S. aureus nasal carriers, four of which were also oral S. aureus carriers. Following the second phase screening, 19 S. aureus nasal carriers were identified, seven of which were S. aureus nasal carriers during the first sampling phase. The second screening phase identified an additional 12 nasal carriers and identified seven persistent nasal carriers, five of which retained the same S. aureus isolate CC from the first round. Confluent growth of S. aureus from primary plating of oral swab and oral rinse samples was recorded for 21.5% (17/79) of S. aureus nasal and oral positive samples for the first round sampling with a reduced rate of 13.92% (11/79) for the second sampling round. The S. aureus cell density range recovered from S. aureus carriers yielding confluent growth from nasal swabs was 2x10⁴ - 2.8 x10⁶ colony forming units (CFU)/swab. A total of 24 MSSA isolates from 21 participants during the first phase of sampling were investigated by DNA microarray profiling. DNA profiling detected 13 different multilocus sequence typing (MLST) clonal complexes (CCs), the most prevalent of which was CC30 (20.8%; 5/24… Advisors/Committee Members: Stassen, Leo.

Subjects/Keywords: Staphylococcus aureus; S. aureus carriage; Dental healthcare worker; Persistent oro/nasal carriage; DNA microarray genotyping; MRSA; MSSA; Antimicrobial agent resistance; S. aureus clones; Chromogenic media; Transient oro/nasal carriage

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APA (6^th Edition):

MALONE, K. M. (2017). An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81817

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

MALONE, KEIRA MARY. “An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81817.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

MALONE, KEIRA MARY. “An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers.” 2017. Web. 27 Feb 2020.

Vancouver:

MALONE KM. An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81817.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

MALONE KM. An investigation of the temporal dynamics of staphylococcus aureus nasal and oropharyngeal carriage amongst oral / dental healthcare workers. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81817

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

30. TIGHE, DONAL. Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease.

Degree: School of Medicine. Discipline of Clinical Medicine, 2017, Trinity College Dublin

URL: http://hdl.handle.net/2262/81873

► Loss of response (LOR) to anti-TNFa therapy is a significant problem, and leads to increased hospitalisation rates, surgical intervention, and steroid dependency. Loss of response… (more)

▼ Loss of response (LOR) to anti-TNFa therapy is a significant problem, and leads to increased hospitalisation rates, surgical intervention, and steroid dependency. Loss of response is multifactorial. However there is an increasing awareness that immunogenicity has a significant role to play in this process. Immunogenicity against anti-TNFa leads to antibody formation. Antibodies against anti-TNFa lead to faster drug clearance, as well as blocking drug activity. This culminates in a reduction in anti-TNFa trough levels and loss of response. Therapeutic drug monitoring (TDM) allows anti-TNFa trough and antibody levels, to be measured and doses adjusted or treatment switched, to help overcome loss of response and improve outcomes. This thesis aimed to explore the impact of loss of response to anti-TNFa, and accurately identify predictors of loss of response. In addition to investigate the role of therapeutic drug monitoring, in assessing and overcoming loss of response. The main laboratory aspect of this thesis concerned the use of ELISA techniques, to accurately measure anti-TNFa trough and antibody levels. In brief a sandwich ELISA technique was used to detect anti-TNFa trough (infliximab & adalimumab) and antibody levels. ELISA microplates were coated with human TNFa. Horse radish peroxidise conjugated goat anti-human IgG Fc fragment antibody was added to serum samples, followed by diluted antibody. Substrate Solution tetramethylbenzidine (TMB) was added to each well, followed by the addition of stop solution. Drug concentrations in serum samples were determined using a standard curve generated from absorbance readings of infliximab or adalimumab. One arm of this thesis looked at a retrospective cohort study, which confirmed the impact of loss of response to anti-TNFa therapy, with an overall LOR rate of 42.5% for a cohort on maintenance treatment one year after commencing therapy. In addition this iv retrospective cohort study identified a number of key predictors of LOR, such as smoking, prior anti-TNFa therapy, as well as the protective benefits of combination therapy. Furthermore the link with biochemical response was confirmed, with a CRP <5 mg/L at the end of induction therapy being a significant predictor of clinical response. The potential and usefulness of TDM was also explored in further detail. A retrospective study looked at the role of role of measuring anti-TNFa trough and antibody levels in a stand-alone fashion. Analysis did not identify a relationship, but there was evidence that patients with low trough levels, and loss of response, had higher biochemical markers of disease activity. Therefore further work was undertaken to establish a role for TDM at the key time-points of end of induction therapy, and during an assessment for secondary loss of response. A prospective study looked at the role of TDM during induction therapy. There was a clear link between higher anti-TNFa trough levels at the end of induction with clinical response rates. For infliximab, mean trough levels in responders were… Advisors/Committee Members: McNamara, Deirdre.

Subjects/Keywords: Inflammatory Bowel Disease

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

TIGHE, D. (2017). Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease. (Thesis). Trinity College Dublin. Retrieved from http://hdl.handle.net/2262/81873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

TIGHE, DONAL. “Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease.” 2017. Thesis, Trinity College Dublin. Accessed February 27, 2020. http://hdl.handle.net/2262/81873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

TIGHE, DONAL. “Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease.” 2017. Web. 27 Feb 2020.

Vancouver:

TIGHE D. Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease. [Internet] [Thesis]. Trinity College Dublin; 2017. [cited 2020 Feb 27]. Available from: http://hdl.handle.net/2262/81873.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

TIGHE D. Optimal use of immunomodulator and biological therapy in Inflammatory Bowel Disease. [Thesis]. Trinity College Dublin; 2017. Available from: http://hdl.handle.net/2262/81873

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations