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NSYSU

1. Chiu, Shu-ling. Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases.

Degree: Master, Biological Sciences, 2017, NSYSU

Carotid stenosis may distort carotid sinus wall, and cause the damage of cardiovascular autonomic nerve function. The aim of the study is to investigate the autonomic nerve function in patients with ischemic stroke in the acute and subacute phases with varying degrees of carotid stenosis. 175 people were diagnosed as acute ischemic stroke for the first time based on examination of brain computed tomography (CT) image and clinical examination by neurologists. Color-coded Carotid Duplex Sonography examination were carried out on these patients to assess the degree of carotid artery stenosis during their hospitalization. The autonomic nerve function tests were performed onset of the occurrence of symptoms < 7 days (acute phase), and of 10-14 days (subacute period). Seven healthy volunteers participated in the study served as the control group. Telephone interviews followed after the patients were discharged at the first, third, sixth, and 12th month to assess their disability status of stroke and the activities of daily living. Patients were divided into three groups based on carotid artery stenosis as â§50%, <50%, and no stenosis. The results showed that compared with control group, the sBP and mBP measurements taken with patients lying down, tilting, and lying down again were higher in the three stroke groups in the acute phases. The dBP measurements taken with subjects lying down, and lying down again after tilting in the acute phases were also higher in the three stroke groups than that of control group. The PP measurements taken with subjects tilting were higher in the three groups of stroke patients than that of the control group in the acute phase.The measurements of sBP, dBP, mBP, and PP with patients of lying down, tilting, and lying down after lying in the group with <50% stenosis were different between values taken in the acute phase and those in subacute phase. The sBP, dBP, mBP values taken with patients tilting in the group with ⧠50% stenosis were different in acute and subacute phase. Compared with healthy adults, acute ischemic stroke patients with different degree of carotid stenosis were higher in sBP, dBP, mBP, and PP values, but no difference shown in HRV and BRS values. Acute ischemic stroke in patients of severe carotid stenosis had poorer prognosis, compared with mild-moderate carotid stenosis and no carotid stenosis. Using Barthel Index as the prognosis index, measurements of sBP, dBP, mBP and PP, and LF/HF in the acute and subacute phases, whether lying postural changes, or lying down, showed no significant difference in acute and subacute phase between poor and good prognosis groups. Patients with lower BRS values taken with posture changes of in the subacute phase had poorer prognosis. With stepwise multiple logistic regression, Age (p < 0.001), NIHSS (p < 0.001) and DM (p = 0.024) were shown to be independent predictors of poor prognosis (Barthel indexâ¦60). Advisors/Committee Members: Lu,Cheng-Hsien (chair), Chang,Hsueh-Wen (committee member), Lo,Yuk-Keung (chair).

Subjects/Keywords: Baroreceptor Reflex Sensitivity; Heart Rate Variability; Carotid stenosis; Autonomic function; Acute ischemic stroke; Low Frequencies/High Frequencies

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APA (6th Edition):

Chiu, S. (2017). Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases. (Thesis). NSYSU. Retrieved from http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0806117-183110

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Chiu, Shu-ling. “Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases.” 2017. Thesis, NSYSU. Accessed November 24, 2017. http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0806117-183110.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Chiu, Shu-ling. “Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases.” 2017. Web. 24 Nov 2017.

Vancouver:

Chiu S. Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases. [Internet] [Thesis]. NSYSU; 2017. [cited 2017 Nov 24]. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0806117-183110.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chiu S. Effects of Carotid Stenosis on the Autonomic Function of Acute Ischemic Stroke Patients in Acute and Subacute Phases. [Thesis]. NSYSU; 2017. Available from: http://etd.lib.nsysu.edu.tw/ETD-db/ETD-search/view_etd?URN=etd-0806117-183110

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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