Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

You searched for id:"handle:10919/83786". One record found.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


Virginia Tech

1. Logan, Amanda Lynn. Satiety induced by neuropeptide FF and gastrin in birds.

Degree: MS, Animal and Poultry Sciences, 2018, Virginia Tech

Mammalian and avian species differ in some appetite-related aspects including how and which neurotransmitters and hormones regulate appetite. The objective of this research was to determine how two satiety-inducing neuropeptides regulate feeding behavior in avian models. Neuropeptide FF (NPFF) was intracerebroventricularly (ICV) injected into Japanese quail and decreased food intake at a dose of 32 nmol. NPFF-injected quail had increased expression levels of hypothalamic melanocortin subtype 3 receptor and decreased expression levels of neuropeptide Y receptor subtype 1 mRNAs compared to vehicle-injected controls. In a second study, gastrin was ICV injected into broiler chicks and decreased food intake at a dose of 500 ng (0.12 nmol). There was increased c-Fos immunoreactivity in the lateral hypothalamus (LH), paraventricular nucleus (PVN), arcuate nucleus, nucleus of the solitary tract, and area postrema at 1 h post-injection. Although a variety of genes were measured in those activated nuclei, there were only differences in melanin-concentrating hormone mRNA in the LH and corticotropin-releasing factor (CRF) mRNA in the PVN, suggesting that CRF signaling was involved in the hypothalamic response to gastrin. However, co-injection of gastrin and astressin, a CRF receptor antagonist did not affect gastrin-induced suppression of food intake, implying that the CRF receptors may not be directly associated with gastrin-induced satiety. Identifying the molecular pathways that mediate the effects of anorexigenic neuropeptides in birds will lead to the development of novel treatment options for appetite-related diseases and increased understanding of factors that affect production efficiency in commercial poultry and survival/resource allocation in wild birds. Advisors/Committee Members: Cline, Mark Andrew (committeechair), Denbow, Donald M (committee member), Gilbert, Elizabeth Ruth (committee member), Liu, Dongmin (committee member).

Subjects/Keywords: hypothalamus; appetite; quail; broiler chick; NPFF; gastrin

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Logan, A. L. (2018). Satiety induced by neuropeptide FF and gastrin in birds. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/83786

Chicago Manual of Style (16th Edition):

Logan, Amanda Lynn. “Satiety induced by neuropeptide FF and gastrin in birds.” 2018. Masters Thesis, Virginia Tech. Accessed July 20, 2018. http://hdl.handle.net/10919/83786.

MLA Handbook (7th Edition):

Logan, Amanda Lynn. “Satiety induced by neuropeptide FF and gastrin in birds.” 2018. Web. 20 Jul 2018.

Vancouver:

Logan AL. Satiety induced by neuropeptide FF and gastrin in birds. [Internet] [Masters thesis]. Virginia Tech; 2018. [cited 2018 Jul 20]. Available from: http://hdl.handle.net/10919/83786.

Council of Science Editors:

Logan AL. Satiety induced by neuropeptide FF and gastrin in birds. [Masters Thesis]. Virginia Tech; 2018. Available from: http://hdl.handle.net/10919/83786

.