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Universitat Autònoma de Barcelona

1. Castillo Flores, Nerea. Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical.

Degree: Departament de Medicina, 2017, Universitat Autònoma de Barcelona

In this study, the fact that most patients receive a similar conditioning allows us to describe the recovery kinetics of the major lymphocyte populations after umbilical cord blood transplantation and to address their predictive factors. The present Doctoral Thesis, therefore, describes the results obtained regarding kinetics and predictive factors of the immune reconstitution after the transplantation of umbilical cord blood in pediatric and adult patients with hematological and non-hematological diseases. Immune reconstitution is an event that has been extensively studied after allogeneic transplantation of hematopoietic progenitors. In this Doctoral Thesis I will refer to the IR as the reconstitution of the population of lymphocytes in absolute numbers and of each of the main lymphocyte subpopulations in a quantitative way. In the works that make up this thesis has been able to study the predictive value of the administration of doses of antithymocytic globulin and the kinetics of lymphocyte recovery in these cases. In summary, the studies that make up this thesis have demonstrated the impact of using a certain dose of antithymocyte globulin, observing an earlier immune reconstitution, lower mortality and greater survival in patients receiving a lower dose of this drug in the conditioning regimen. * This Doctoral Thesis contains the following sections: - Glossary of abbreviations -Discussion - Motivation of the thesis -Conclusions -Backgrounds and field of study -Bibliography -Introduction -Generalities umbilical cord blood transplantation -Justification of the study - Study hypotheses and objectives of the thesis Advisors/Committee Members: [email protected] (authoremail), true (authoremailshow), Querol Giner, Sergi (director), Ribera Santasusana, Josep Mª (tutor), true (authorsendemail).

Subjects/Keywords: Transplantament; Transplante; Transplant; Sang de cordó umbilical; Sangre de cordón umbilical; Cord blood; Reconstitució inmune; Reconstitución inmune; Inmune reconstitution; Ciències de la Salut; 616.4

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Castillo Flores, N. (2017). Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical. (Thesis). Universitat Autònoma de Barcelona. Retrieved from http://hdl.handle.net/10803/403812

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Castillo Flores, Nerea. “Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical.” 2017. Thesis, Universitat Autònoma de Barcelona. Accessed August 23, 2017. http://hdl.handle.net/10803/403812.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Castillo Flores, Nerea. “Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical.” 2017. Web. 23 Aug 2017.

Vancouver:

Castillo Flores N. Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical. [Internet] [Thesis]. Universitat Autònoma de Barcelona; 2017. [cited 2017 Aug 23]. Available from: http://hdl.handle.net/10803/403812.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Castillo Flores N. Cinética y factores predictivos de la reconstitución inmune en el trasplante de sangre de cordón umbilical. [Thesis]. Universitat Autònoma de Barcelona; 2017. Available from: http://hdl.handle.net/10803/403812

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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