Advanced search options

Advanced Search Options 🞨

Browse by author name (“Author name starts with…”).

Find ETDs with:

in
/  
in
/  
in
/  
in

Written in Published in Earliest date Latest date

Sorted by

Results per page:

You searched for id:"handle:10217/181336". One record found.

Search Limiters

Last 2 Years | English Only

No search limiters apply to these results.

▼ Search Limiters


Colorado State University

1. Grimm, Nathan Carlisle. Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference.

Degree: 2017, Colorado State University

INTRODUCTION: To determine if liposomal (L) encapsulated alpha-lipoic acid (0.5g), benfotiamine (0.5g) and curcumin (2.0g) (ABC) would prevent the unfavorable metabolic consequences of sedentary high-fat overfeeding in healthy young adults. METHODS: 29 young (18-30 years), healthy, physically active men and women were randomly assigned to ingest placebo (n=9), ABC (n=10), or L-ABC (n=10) twice daily for 28 days. Between days 22 and 28 all participants abstained from their normal regular exercise and consumed a high calorie, high fat diet. RESULTS: On Day 29, circulating alpha lipoic acid was greater (p<0.01) in L-ABC (412±73 ng/mL) compared with ABC (154±33 ng/mL). During the sedentary high fat overfeeding, dietary intake was not different (p>0.60) between groups (~3,400 kcal/day; ~50% from fat). Sedentary high fat overfeeding increased (p<0.05) waist circumference in the placebo (+2.7±2.7 cm) and ABC (+3.3±2.0) groups but not the L-ABC group (+0.7±2.7). The magnitudes of increase (p<0.05) in body mass (1.7±0.3 kg), fat mass (0.7±0.2 kg), and blood pressure (3±1 mmHg) and decrease (p<0.05) in insulin sensitivity (Matsuda Index: -2.9±0.9) after overfeeding were not different between groups (all p>0.50). DISCUSSION: Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin: 1) promoted alpha-lipoic acid bioavailability; and, 2) prevented sedentary high-fat overfeeding mediated increases in waist circumference in usually active healthy young adults. These data may have important public health implications for periods of inactive overconsumption such as during seasonal celebrations. Advisors/Committee Members: Bell, Christopher (advisor), Dooley, Gregory (committee member), Hickey, Matthew (committee member).

Subjects/Keywords: Insulin; Overfeeding; Glucose; Supplement; Nutraceutical

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Grimm, N. C. (2017). Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference. (Thesis). Colorado State University. Retrieved from http://hdl.handle.net/10217/181336

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Grimm, Nathan Carlisle. “Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference.” 2017. Thesis, Colorado State University. Accessed August 23, 2017. http://hdl.handle.net/10217/181336.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Grimm, Nathan Carlisle. “Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference.” 2017. Web. 23 Aug 2017.

Vancouver:

Grimm NC. Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference. [Internet] [Thesis]. Colorado State University; 2017. [cited 2017 Aug 23]. Available from: http://hdl.handle.net/10217/181336.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Grimm NC. Liposomal encapsulated alpha-lipoic acid, benfotiamine and curcumin prevent overfeeding mediated increases in waist circumference. [Thesis]. Colorado State University; 2017. Available from: http://hdl.handle.net/10217/181336

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

.