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You searched for +publisher:"Virginia Tech" +contributor:("Jacobson, John"). Showing records 1 – 3 of 3 total matches.

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Virginia Tech

1. Kline, Kristen Alissa. Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin.

Degree: MS, Animal and Poultry Sciences, 1997, Virginia Tech

Feeding a fat-containing diet to the exercising horse is a facile way to increase energy density without risking the complications associated with hydrolyzable carbohydrates. Fat adaptation may also result in increases in the utilization of free fatty acids for fuel during exercise and sparing of muscle glycogen. Phosphatidylcholine, the main component of lecithins, can influence muscle contraction and improve endurance capacity during exercise. When it is combined with corn oil in a total mixed ration, soy lecithin is both highly digestible and palatable to horses. Our objectives in this study were to compare the effects of incremental exercise and isocaloric control (CON), corn oil (CO), and a soy lecithin/corn oil (LE) diets on plasma free fatty acids (FFA), cholesterol, glycerol, triglyceride (TG), lactate, and glucose. Also three different statistical models were compared for goodness of fit to the lactate curve. Plasma lactate and glucose both increased slowly early in the incremental exercise test (IET), then increased rapidly as the work intensity increased. Both decreased during recovery. No effects of IET or diet were found for either of these variables. Plasma TG was unchanged during exercise, but increased rapidly during recovery. Plasma FFA decreased from resting early in the IET then remained steady throughout the remainder of exercise. During recovery a rapid increase was exhibited. Plasma glycerol was constant during exercise, but increased during recovery. Plasma cholesterol did not change during exercise or recovery. Diet affected plasma FFA. Plasma FFA were lower for the CO and LE diets than the CON diet during the IET. Plasma glycerol was lower for the CO diet than the CON diet during the IET, with the LE diet intermediate between the two. Plasma cholesterol was higher for the CO and LE diets than the CON diet during the IET. A segmented model and an exponential model were found to have a good fit to the lactate curve. A point of inflection for a rapid increase in plasma lactate during incremental exercise was discovered. When this model was applied to diet, no differences in lactate threshold were found between the diets. Some criteria for fat adaptation were met, namely diet affected plasma FFA, glycerol, and cholesterol. However diet did not affect plasma TG, lactate, or glucose. This indicates that the rate of fatty acid oxidation was increased following fat adaptation, but it did not affect the rate of glucose oxidation and glycolysis during exercise. A lactate threshold for the equine can be obtained using a broken line model. Further studies using this approach are needed to establish its correlation with performance. Advisors/Committee Members: Kronfeld, David S. (committeechair), Jacobson, John (committee member), Denbow, Donald Michael (committee member).

Subjects/Keywords: treadmill; fat adaptation; equine

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APA (6th Edition):

Kline, K. A. (1997). Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/37030

Chicago Manual of Style (16th Edition):

Kline, Kristen Alissa. “Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin.” 1997. Masters Thesis, Virginia Tech. Accessed August 12, 2020. http://hdl.handle.net/10919/37030.

MLA Handbook (7th Edition):

Kline, Kristen Alissa. “Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin.” 1997. Web. 12 Aug 2020.

Vancouver:

Kline KA. Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin. [Internet] [Masters thesis]. Virginia Tech; 1997. [cited 2020 Aug 12]. Available from: http://hdl.handle.net/10919/37030.

Council of Science Editors:

Kline KA. Metabolic effects of incremental exercise on Arabian horses fed diets containing corn oil and soy lecithin. [Masters Thesis]. Virginia Tech; 1997. Available from: http://hdl.handle.net/10919/37030


Virginia Tech

2. Kuntz, Charles A. Controlled cross circulation: effects on donor hemodynamics.

Degree: MS, Veterinary Medical Sciences, 1994, Virginia Tech

Controlled cross circulation was performed in six pairs of dogs to assess hemodynamic changes in the donor dog. Cardiopulmonary bypass was performed for 45 minutes, with an aortic cross clamp time of 3 5 minutes. Anesthesia was maintained in the donor dog with 1.8% end-tidal isoflurane. Parameters before and after controlled cross circulation were compared using a Wilcoxon Signed Rank Test. Donor left ventricular dP/dt max, pulmonary capillary wedge pressure, blood volume, systemic vascular resistance, heart rate, total protein, platelet count, and white blood cell count did not change significantly. Donor cardiac output, end diastolic volume, central venous pressure, stroke volume, mean arterial blood pressure, and packed cell volume all decreased significantly (p<O.05). Recipient blood volume and donor cardiac performance (LV dP/dt max/end diastolic volume) increased significantly (p<O.05). Advisors/Committee Members: Johnston, Spencer A. (committeechair), Shires, Peter K. (committee member), Martin, Robert A. (committee member), Larson, Martha Moon (committee member), Jacobson, John (committee member), Lee, John C. (committee member).

Subjects/Keywords: Hemodynamics; LD5655.V855 1994.K868

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APA (6th Edition):

Kuntz, C. A. (1994). Controlled cross circulation: effects on donor hemodynamics. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/42909

Chicago Manual of Style (16th Edition):

Kuntz, Charles A. “Controlled cross circulation: effects on donor hemodynamics.” 1994. Masters Thesis, Virginia Tech. Accessed August 12, 2020. http://hdl.handle.net/10919/42909.

MLA Handbook (7th Edition):

Kuntz, Charles A. “Controlled cross circulation: effects on donor hemodynamics.” 1994. Web. 12 Aug 2020.

Vancouver:

Kuntz CA. Controlled cross circulation: effects on donor hemodynamics. [Internet] [Masters thesis]. Virginia Tech; 1994. [cited 2020 Aug 12]. Available from: http://hdl.handle.net/10919/42909.

Council of Science Editors:

Kuntz CA. Controlled cross circulation: effects on donor hemodynamics. [Masters Thesis]. Virginia Tech; 1994. Available from: http://hdl.handle.net/10919/42909


Virginia Tech

3. Sysel, Annette M. Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects.

Degree: MS, Veterinary Medical Sciences, 1996, Virginia Tech

In Part 1, amphotericin B-induced synovitis of the left tarsocrural joint was used to create hindlimb lameness in 11 horses. Caudal epidural catheters were placed and advanced to the lumbosacral region. Baseline heart and respiratory rates were recorded and horses were videotaped at a walk and trot. Treated horses received 0.2 mg/kg morphine sulfate and 30 ug/kg detomidine hydrochloride through the epidural catheter; control horses received an equivalent volume of physiologic saline solution through the catheter. At hourly intervals after epidural injection for a total of 6 hours, heart and respiratory rates were recorded and horses were videotaped walking and trotting. At the end of the observation period, video recordings were scrambled onto a master videotape. Lamenesses were scored by 3 investigators. Lameness grades, heart rates and respiratory rates were compared. There was a significant decrease in lameness grades after treatment with epidural morphine and detomidine. Initially, heart rates significantly increased in control horses and decreased in treated horses. A similar trend occurred for respiratory rates. In Part 2, caudal epidural catheters were used to administer injections to 10 horses every 12 hours for 14 days. Treated horses received 0.2 nlg/kg morphine sulfate and 30 ug/kg detomidine hydrochloride, and control horses received an equivalent volume of physiologic saline solution. Body weights were recorded on days 1 and 14. Rectal temperature, heart rate, respiratory rate and gastrointestinal motility were recorded twice daily, and daily hay and water consumption was measured. Horses were euthanatized day 15. Atlanto-occipital cerebrospinal fluid samples were submitted for bacteriologic culture and determination of white and red blood cell counts and protein and glucose concentrations. Post mortem examinations were performed and representative samples of the spinal cord and surrounding tissues were taken from cervicothoracic, thoracolumbar, lumbosacral, sacral and catheter entry point regions. Spinal tissue segments from these regions were graded for histologic degree of inflammation and fibrosis. Cerebrospinal fluid values and spinal tissue segment inflammation and fibrosis grades were compared between control and treated horses, and between all 10 catheterized study horses and 6 uncatheterized horses. No problems were encountered with epidural catheter maintenance or injection. No significant difference was identified in body weight change, daily variables or hay and water consumption between control and treated horses. All cerebrospinal fluid cultures were negative for growth. No significant difference in cerebrospinal fluid values or spinal tissue inflammation or fibrosis grades for any segment was demonstrated between control and treated horses. However, when compared to uncatheterized horses, cerebrospinal fluid red blood cell counts were marginally higher and protein concentrations were significantly higher in catheterized horses. As well, lumbosacral and… Advisors/Committee Members: Pleasant, Robert Scott (committeechair), Jacobson, John D. (committee member), Moll, H. David (committee member), Sponenberg, D. Phillip (committee member), Eyre, Peter (committee member).

Subjects/Keywords: epidural; catheter; morphine; detomidine; horses; LD5655.V855 1996.S974

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APA (6th Edition):

Sysel, A. M. (1996). Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects. (Masters Thesis). Virginia Tech. Retrieved from http://hdl.handle.net/10919/44476

Chicago Manual of Style (16th Edition):

Sysel, Annette M. “Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects.” 1996. Masters Thesis, Virginia Tech. Accessed August 12, 2020. http://hdl.handle.net/10919/44476.

MLA Handbook (7th Edition):

Sysel, Annette M. “Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects.” 1996. Web. 12 Aug 2020.

Vancouver:

Sysel AM. Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects. [Internet] [Masters thesis]. Virginia Tech; 1996. [cited 2020 Aug 12]. Available from: http://hdl.handle.net/10919/44476.

Council of Science Editors:

Sysel AM. Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects. [Masters Thesis]. Virginia Tech; 1996. Available from: http://hdl.handle.net/10919/44476

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