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You searched for +publisher:"Vanderbilt University" +contributor:("John A. Capra"). Showing records 1 – 13 of 13 total matches.

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Vanderbilt University

1. Sivley, Robert Michael. Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity.

Degree: MS, Biomedical Informatics, 2017, Vanderbilt University

 The spatial distribution of genetic variation within proteins is shaped by evolutionary constraint and thus can provide insights into the functional importance of protein regions… (more)

Subjects/Keywords: ripleys k; spatial; genomics; genetics; protein structure

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Sivley, R. M. (2017). Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity. (Thesis). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/10634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Sivley, Robert Michael. “Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity.” 2017. Thesis, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/10634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Sivley, Robert Michael. “Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity.” 2017. Web. 07 Mar 2021.

Vancouver:

Sivley RM. Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity. [Internet] [Thesis]. Vanderbilt University; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/10634.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Sivley RM. Comprehensive Analysis of the Spatial Distribution of Missense Variants in Protein Structures Reveals Patterns Predictive of Pathogenicity. [Thesis]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/10634

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Vanderbilt University

2. Benton, Mary Lauren. Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function.

Degree: MS, Biomedical Informatics, 2018, Vanderbilt University

 Non-coding gene regulatory enhancers are essential to transcription in mammalian cells. As a result, a large variety of experimental and computational strategies have been developed… (more)

Subjects/Keywords: gene regulation

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APA (6th Edition):

Benton, M. L. (2018). Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function. (Thesis). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/13969

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Benton, Mary Lauren. “Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function.” 2018. Thesis, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/13969.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Benton, Mary Lauren. “Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function.” 2018. Web. 07 Mar 2021.

Vancouver:

Benton ML. Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function. [Internet] [Thesis]. Vanderbilt University; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/13969.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Benton ML. Genome-wide Enhancer Maps Differ Significantly in their Genomic Distribution, Evolution, and Function. [Thesis]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/13969

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


Vanderbilt University

3. Chen, Ling. UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING.

Degree: PhD, Biological Sciences, 2019, Vanderbilt University

 Enhancers are genomic regions distal to promoters that bind transcription factors (TFs) to regulate the dynamic spatiotemporal patterns of gene expression required for proper differentiation… (more)

Subjects/Keywords: regulatory genome; deep learning; enhancer; machine learning

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APA (6th Edition):

Chen, L. (2019). UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14530

Chicago Manual of Style (16th Edition):

Chen, Ling. “UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING.” 2019. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/14530.

MLA Handbook (7th Edition):

Chen, Ling. “UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING.” 2019. Web. 07 Mar 2021.

Vancouver:

Chen L. UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING. [Internet] [Doctoral dissertation]. Vanderbilt University; 2019. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/14530.

Council of Science Editors:

Chen L. UNDERSTANDING THE EVOLUTION AND SEQUENCE ARCHITECTURE OF GENE REGULATORY ELEMENTS THROUGH MACHINE LEARNING. [Doctoral Dissertation]. Vanderbilt University; 2019. Available from: http://hdl.handle.net/1803/14530


Vanderbilt University

4. Simonti, Corinne Nicole. Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution.

Degree: PhD, Human Genetics, 2017, Vanderbilt University

 The genomics era has seen a staggering increase in the number of whole genome sequences. This has bolstered studies of human populations, and revealed regions… (more)

Subjects/Keywords: PheWAS; Biobank; Neanderthal; Evolution

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APA (6th Edition):

Simonti, C. N. (2017). Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11256

Chicago Manual of Style (16th Edition):

Simonti, Corinne Nicole. “Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution.” 2017. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/11256.

MLA Handbook (7th Edition):

Simonti, Corinne Nicole. “Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution.” 2017. Web. 07 Mar 2021.

Vancouver:

Simonti CN. Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution. [Internet] [Doctoral dissertation]. Vanderbilt University; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/11256.

Council of Science Editors:

Simonti CN. Leveraging Biobanks and PheWAS to Uncover the Health Consequences of Recent Human Evolution. [Doctoral Dissertation]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/11256


Vanderbilt University

5. Kara, Nergis. microRNA Function in Zebrafish Development and Regeneration.

Degree: PhD, Biological Sciences, 2018, Vanderbilt University

 microRNAs (miRNAs) are a family of highly conserved small noncoding RNAs that post transcriptionally regulate gene expression and play important roles in many cellular processes… (more)

Subjects/Keywords: zebrafish; microRNA; development; regeneration; retina; Müller glia

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APA (6th Edition):

Kara, N. (2018). microRNA Function in Zebrafish Development and Regeneration. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/14353

Chicago Manual of Style (16th Edition):

Kara, Nergis. “microRNA Function in Zebrafish Development and Regeneration.” 2018. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/14353.

MLA Handbook (7th Edition):

Kara, Nergis. “microRNA Function in Zebrafish Development and Regeneration.” 2018. Web. 07 Mar 2021.

Vancouver:

Kara N. microRNA Function in Zebrafish Development and Regeneration. [Internet] [Doctoral dissertation]. Vanderbilt University; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/14353.

Council of Science Editors:

Kara N. microRNA Function in Zebrafish Development and Regeneration. [Doctoral Dissertation]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/14353


Vanderbilt University

6. Sivley, Robert Michael. Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery.

Degree: PhD, Biomedical Informatics, 2018, Vanderbilt University

 Patterns of genetic variation along the human genome provide insight into functional and evolutionary constraints on different loci. Quantifying these patterns of constraint improves our… (more)

Subjects/Keywords: selective constraint; spatial constraint; structural biology; human genetics

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APA (6th Edition):

Sivley, R. M. (2018). Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/10433

Chicago Manual of Style (16th Edition):

Sivley, Robert Michael. “Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery.” 2018. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/10433.

MLA Handbook (7th Edition):

Sivley, Robert Michael. “Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery.” 2018. Web. 07 Mar 2021.

Vancouver:

Sivley RM. Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery. [Internet] [Doctoral dissertation]. Vanderbilt University; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/10433.

Council of Science Editors:

Sivley RM. Constraint on Rare Protein-Coding Variation: Pathogenicity Prediction and Phenotypic Discovery. [Doctoral Dissertation]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/10433


Vanderbilt University

7. Lind, Abigail Lee. The evolution of secondary metabolism regulation and pathways in the Aspergillus genus.

Degree: PhD, Biomedical Informatics, 2017, Vanderbilt University

 Filamentous fungi produce a diverse array of secondary metabolites (SMs) that play ecological roles in defense, virulence, and inter- and intra-species communication. Fungal SMs have… (more)

Subjects/Keywords: genomics; evolution; gene regulation; secondary metabolism

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APA (6th Edition):

Lind, A. L. (2017). The evolution of secondary metabolism regulation and pathways in the Aspergillus genus. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/13274

Chicago Manual of Style (16th Edition):

Lind, Abigail Lee. “The evolution of secondary metabolism regulation and pathways in the Aspergillus genus.” 2017. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/13274.

MLA Handbook (7th Edition):

Lind, Abigail Lee. “The evolution of secondary metabolism regulation and pathways in the Aspergillus genus.” 2017. Web. 07 Mar 2021.

Vancouver:

Lind AL. The evolution of secondary metabolism regulation and pathways in the Aspergillus genus. [Internet] [Doctoral dissertation]. Vanderbilt University; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/13274.

Council of Science Editors:

Lind AL. The evolution of secondary metabolism regulation and pathways in the Aspergillus genus. [Doctoral Dissertation]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/13274


Vanderbilt University

8. Allison, Brittany Ann. Computational Design of Protein-Ligand Interfaces Using RosettaLigand.

Degree: PhD, Chemistry, 2016, Vanderbilt University

 Computational design of protein-ligand interfaces expands understanding of the basic forces involved in molecular recognition, and also contributes to the development of protein therapeutics. My… (more)

Subjects/Keywords: protein engineering; protein ligand binding; RosettaLigand; Rosetta; protein small molecule interactions; interface design; computational design; ligand macromolecule recognition; NMR; binding affinity

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APA (6th Edition):

Allison, B. A. (2016). Computational Design of Protein-Ligand Interfaces Using RosettaLigand. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11616

Chicago Manual of Style (16th Edition):

Allison, Brittany Ann. “Computational Design of Protein-Ligand Interfaces Using RosettaLigand.” 2016. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/11616.

MLA Handbook (7th Edition):

Allison, Brittany Ann. “Computational Design of Protein-Ligand Interfaces Using RosettaLigand.” 2016. Web. 07 Mar 2021.

Vancouver:

Allison BA. Computational Design of Protein-Ligand Interfaces Using RosettaLigand. [Internet] [Doctoral dissertation]. Vanderbilt University; 2016. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/11616.

Council of Science Editors:

Allison BA. Computational Design of Protein-Ligand Interfaces Using RosettaLigand. [Doctoral Dissertation]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/11616


Vanderbilt University

9. Brooks, Andrew Wallace. The Role of Host-Associated Factors on Metazoan Microbiome Assembly.

Degree: PhD, Human Genetics, 2019, Vanderbilt University

 Gut microbiomes, the genetic repertoire for millions to trillions of microbes residing throughout each metazoan’s digestive tract, are shaped by their host and environment. Composed… (more)

Subjects/Keywords: Microbiome; Metagenome; Metagenomics; Human Gut; Microbiology; Genetics; Phylosymbiosis

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APA (6th Edition):

Brooks, A. W. (2019). The Role of Host-Associated Factors on Metazoan Microbiome Assembly. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12320

Chicago Manual of Style (16th Edition):

Brooks, Andrew Wallace. “The Role of Host-Associated Factors on Metazoan Microbiome Assembly.” 2019. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/12320.

MLA Handbook (7th Edition):

Brooks, Andrew Wallace. “The Role of Host-Associated Factors on Metazoan Microbiome Assembly.” 2019. Web. 07 Mar 2021.

Vancouver:

Brooks AW. The Role of Host-Associated Factors on Metazoan Microbiome Assembly. [Internet] [Doctoral dissertation]. Vanderbilt University; 2019. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/12320.

Council of Science Editors:

Brooks AW. The Role of Host-Associated Factors on Metazoan Microbiome Assembly. [Doctoral Dissertation]. Vanderbilt University; 2019. Available from: http://hdl.handle.net/1803/12320


Vanderbilt University

10. O'Brien, Timothy Daniel. Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer.

Degree: PhD, Human Genetics, 2017, Vanderbilt University

 Lung cancer is classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC has several subtypes, but the… (more)

Subjects/Keywords: RNA-Seq; WES; somatic mutations; differential expression; enhancer; eQTL; lung cancer subtypes; GWAS

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APA (6th Edition):

O'Brien, T. D. (2017). Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12384

Chicago Manual of Style (16th Edition):

O'Brien, Timothy Daniel. “Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer.” 2017. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/12384.

MLA Handbook (7th Edition):

O'Brien, Timothy Daniel. “Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer.” 2017. Web. 07 Mar 2021.

Vancouver:

O'Brien TD. Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer. [Internet] [Doctoral dissertation]. Vanderbilt University; 2017. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/12384.

Council of Science Editors:

O'Brien TD. Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer. [Doctoral Dissertation]. Vanderbilt University; 2017. Available from: http://hdl.handle.net/1803/12384


Vanderbilt University

11. Hall, Jacob B. The genetics of age-related macular degeneration: exploring pathway and epistatic effects.

Degree: PhD, Human Genetics, 2016, Vanderbilt University

 Age-related macular degeneration (AMD) is a neurodegenerative disease that leads to a loss of central vision and is the leading cause of blindness in the… (more)

Subjects/Keywords: mixed linear models; macular degeneration; heritability; genetics; interactions; epistasis

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APA (6th Edition):

Hall, J. B. (2016). The genetics of age-related macular degeneration: exploring pathway and epistatic effects. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/11621

Chicago Manual of Style (16th Edition):

Hall, Jacob B. “The genetics of age-related macular degeneration: exploring pathway and epistatic effects.” 2016. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/11621.

MLA Handbook (7th Edition):

Hall, Jacob B. “The genetics of age-related macular degeneration: exploring pathway and epistatic effects.” 2016. Web. 07 Mar 2021.

Vancouver:

Hall JB. The genetics of age-related macular degeneration: exploring pathway and epistatic effects. [Internet] [Doctoral dissertation]. Vanderbilt University; 2016. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/11621.

Council of Science Editors:

Hall JB. The genetics of age-related macular degeneration: exploring pathway and epistatic effects. [Doctoral Dissertation]. Vanderbilt University; 2016. Available from: http://hdl.handle.net/1803/11621


Vanderbilt University

12. Moon, Jiyun. Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy.

Degree: PhD, Biological Sciences, 2019, Vanderbilt University

 Eutherian pregnancy is characterized by relatively prolonged gestation and early establishment of direct maternal-fetal contact. In order to support extended growth of a genetically distinct… (more)

Subjects/Keywords: Enhancers; Reproductive Immunity Genes; Human Evolution; Recent Positive Selection; Pregnancy

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APA (6th Edition):

Moon, J. (2019). Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/12278

Chicago Manual of Style (16th Edition):

Moon, Jiyun. “Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy.” 2019. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/12278.

MLA Handbook (7th Edition):

Moon, Jiyun. “Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy.” 2019. Web. 07 Mar 2021.

Vancouver:

Moon J. Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy. [Internet] [Doctoral dissertation]. Vanderbilt University; 2019. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/12278.

Council of Science Editors:

Moon J. Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy. [Doctoral Dissertation]. Vanderbilt University; 2019. Available from: http://hdl.handle.net/1803/12278


Vanderbilt University

13. Kim, Mara. Genestation: The Genomic Search Engine Toolkit.

Degree: PhD, Biological Sciences, 2018, Vanderbilt University

 Recent advances in sequencing technology have greatly decreased the cost and increased the availability of genomic data. Armed with this rich base of information, it… (more)

Subjects/Keywords: Database; Search Engine; Genomics

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APA (6th Edition):

Kim, M. (2018). Genestation: The Genomic Search Engine Toolkit. (Doctoral Dissertation). Vanderbilt University. Retrieved from http://hdl.handle.net/1803/15529

Chicago Manual of Style (16th Edition):

Kim, Mara. “Genestation: The Genomic Search Engine Toolkit.” 2018. Doctoral Dissertation, Vanderbilt University. Accessed March 07, 2021. http://hdl.handle.net/1803/15529.

MLA Handbook (7th Edition):

Kim, Mara. “Genestation: The Genomic Search Engine Toolkit.” 2018. Web. 07 Mar 2021.

Vancouver:

Kim M. Genestation: The Genomic Search Engine Toolkit. [Internet] [Doctoral dissertation]. Vanderbilt University; 2018. [cited 2021 Mar 07]. Available from: http://hdl.handle.net/1803/15529.

Council of Science Editors:

Kim M. Genestation: The Genomic Search Engine Toolkit. [Doctoral Dissertation]. Vanderbilt University; 2018. Available from: http://hdl.handle.net/1803/15529

.