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You searched for +publisher:"University of Southern California" +contributor:("Deapen, Dennis"). Showing records 1 – 3 of 3 total matches.

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University of Southern California

1. Lu, Yani. Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study.

Degree: PhD, Preventive Medicine (Health Behavior), 2009, University of Southern California

The incidence of Non-Hodgkin lymphoma (NHL) has risen for several decades. However, few risk factors have been identified and most of the etiology of NHL has not been explained.; This dissertation presents the results for family history of hematopoietic malignancy, body size, physical activity, and exogenous hormone use on B-cell NHL risk among women aged 22 to 84 years old at cohort entry in the California Teachers Study. Multivariable adjusted relative risks (RR) and 95% confidence intervals (CI) were estimated by fitting Cox proportional hazards models. A history of hematopoietic malignancy in any first-degree relative was associated with increased B-cell NHL risk (RR=1.52, 95% CI=1.11-2.07). Risk patterns vary by type of hematopoietic malignancy and the gender of the relative. Height was positively associated with all B-cell NHL combined (P for trend=0.0002) and B-cell chronic lymphocytic leukemias/small lymphocytic lymphomas (CLL/SLL) subtype (P for trend=0.001). Weight and body mass index (BMI, kg/m2) at age 18 were predictors for B-cell NHL overall. Women who used oral contraceptives (OC) had lower risk of B-cell NHL than women who had never used OC (RR=0.82, 95%CI=0.66-1.03). Although the overall association between B-cell NHL and HT use was null (RR=1.05, 95%CI=0.82-1.34), current users of unopposed estrogen therapy (ET) had greater risk (RR=1.36, 95%CI=1.00-1.87) and current users of estrogen plus progestin therapy (EPT) had lower risk (RR=0.80, 95%CI=0.58-1.10) than women with no HT use. Furthermore, risk of B-cell NHL declined as duration of EPT use increased, whereas no duration of use effect was observed for ET use.; These findings indicate: 1) Family history of hematopoietic malignancy is positively associated with B-cell NHL risk and risk patterns vary by type of hematopoietic malignancy and the gender of the relative; 2) Greater height, which may reflect early life immune function, infectious exposures, nutrition, or growth hormone levels, may play a role in NHL etiology; body size at age 18 may be more relevant to NHL etiology than that in later life; 3) Unopposed estrogen use may increase the risk of B-cell NHL, but combinations of estrogen and progestin, as EPT or OC, may decrease risk. Advisors/Committee Members: Bernstein, Leslie (Committee Chair), Mack, Wendy J. (Committee Member), Deapen, Dennis (Committee Member), Taylor, Clive R. (Committee Member).

Subjects/Keywords: non-Hodgkin lymphoma; family history; body size; physical activity; oral contraceptive; menopausal hormonal therapy

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APA (6th Edition):

Lu, Y. (2009). Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/172717/rec/6183

Chicago Manual of Style (16th Edition):

Lu, Yani. “Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study.” 2009. Doctoral Dissertation, University of Southern California. Accessed December 06, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/172717/rec/6183.

MLA Handbook (7th Edition):

Lu, Yani. “Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study.” 2009. Web. 06 Dec 2019.

Vancouver:

Lu Y. Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study. [Internet] [Doctoral dissertation]. University of Southern California; 2009. [cited 2019 Dec 06]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/172717/rec/6183.

Council of Science Editors:

Lu Y. Study of risk factors of B-cell non-Hodgkin lymphoma (NHL) in the California Teachers Study. [Doctoral Dissertation]. University of Southern California; 2009. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/172717/rec/6183


University of Southern California

2. Escobedo, Anna Loraine Agustín. Application of geospatial methods to cancer surveillance data to improve cancer prevention and control.

Degree: PhD, Epidemiology, 2015, University of Southern California

Incidence of melanoma is increasing worldwide, over and above the impact of screening. While rates are high in certain parts of the United States, melanoma is still a fairly rare disease and this has contributed to the lack of adequately‐powered randomized clinical trials to examine the effects of population‐based screening on melanoma outcomes. For such settings where the cost‐effectiveness of population‐based campaigns cannot be easily established, experts are leaning towards focusing on high‐risk subpopulations. However, there are currently major gaps in the literature related to the identification of high‐risk subpopulations to target for early‐detection campaigns in the country. Because of the availability of population‐based cancer surveillance data, heterogeneously and widely distributed population and disparities in access‐to‐care, Los Angeles County in California presents an ideal setting to explore important factors to be considered when identifying geographic and demographic priorities for early melanoma detection, a goal of this dissertation. In addition, the combined knowledge of who and where high‐risk subpopulations are were used to evaluate the performance of potential targeted early‐detection campaigns in the county. Study findings can guide and improve the reach of existing early‐detection programs. Finding melanoma early among subpopulations who are more likely to present them in later stages is a cost‐effective approach that will substantially decrease melanoma mortality rates and result to considerable economic savings for the public. Advisors/Committee Members: Cockburn, Myles (Committee Chair), Franklin, Meredith (Committee Member), Wilson, John P. (Committee Member), Peng, David H. (Committee Member), Deapen, Dennis (Committee Member).

Subjects/Keywords: cancer; melanoma; incidence; late stage; neoplasm staging; diagnosis; cancer prevention; cancer control; adult; adolescent; geographic information systems; GIS; spatial; geospatial; geography; demography; California; Los Angeles County; cost‐effective; targeted; screening; early‐detection; high‐risk; population‐based; access to care; health services accessibility; dermatology; health insurance; distance; health care; providers; residence characteristics; priority; minority groups; Latino; Hispanic; non‐Hispanic white; epidemiology; poverty; socioeconomic status; socioeconomic factors; odds ratio; risk; United States; social class; SEER program; Cancer Surveillance Program; SaTScan; cluster; scan statistics; hotspot; Receiver Operating Characteristic

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Escobedo, A. L. A. (2015). Application of geospatial methods to cancer surveillance data to improve cancer prevention and control. (Doctoral Dissertation). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/605025/rec/855

Chicago Manual of Style (16th Edition):

Escobedo, Anna Loraine Agustín. “Application of geospatial methods to cancer surveillance data to improve cancer prevention and control.” 2015. Doctoral Dissertation, University of Southern California. Accessed December 06, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/605025/rec/855.

MLA Handbook (7th Edition):

Escobedo, Anna Loraine Agustín. “Application of geospatial methods to cancer surveillance data to improve cancer prevention and control.” 2015. Web. 06 Dec 2019.

Vancouver:

Escobedo ALA. Application of geospatial methods to cancer surveillance data to improve cancer prevention and control. [Internet] [Doctoral dissertation]. University of Southern California; 2015. [cited 2019 Dec 06]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/605025/rec/855.

Council of Science Editors:

Escobedo ALA. Application of geospatial methods to cancer surveillance data to improve cancer prevention and control. [Doctoral Dissertation]. University of Southern California; 2015. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll3/id/605025/rec/855


University of Southern California

3. West-Wright, Carmen Nicole. Lifetime physical activity and its effects on breast cancer survival.

Degree: MS, Epidemiology, 2008, University of Southern California

Introduction: Physical activity has long been suggested as a modifiable lifestyle factor that aids in the reduction of breast cancer risk (1-13). The relationship between physical activity and breast cancer survival is not as clearly defined as the association with risk.; Methods: We examined the association of lifetime recreational physical activity on breast cancer survival in a cohort of 133,479 women established in 1995-1996 who had a first primary invasive breast cancer after completion of the baseline questionnaire, 3190 women were included in this analysis.; Results: Summarized lifetime was strongly predictive of the risk of dying from breast cancer for patients irrespective of estrogen receptor status and was predictive of all causes of death for patients with ER- breast cancers.; Conclusions: These results suggest that physical activity prior to breast cancer diagnosis particularly, lifetime physical activity, may decrease the risk associated with death from breast cancer or from any cause. Advisors/Committee Members: Bernstein, Leslie (Committee Chair), Ursin, Giske (Committee Member), Deapen, Dennis (Committee Member).

Subjects/Keywords: breast cancer; physical activity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

West-Wright, C. N. (2008). Lifetime physical activity and its effects on breast cancer survival. (Masters Thesis). University of Southern California. Retrieved from http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/51282/rec/3815

Chicago Manual of Style (16th Edition):

West-Wright, Carmen Nicole. “Lifetime physical activity and its effects on breast cancer survival.” 2008. Masters Thesis, University of Southern California. Accessed December 06, 2019. http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/51282/rec/3815.

MLA Handbook (7th Edition):

West-Wright, Carmen Nicole. “Lifetime physical activity and its effects on breast cancer survival.” 2008. Web. 06 Dec 2019.

Vancouver:

West-Wright CN. Lifetime physical activity and its effects on breast cancer survival. [Internet] [Masters thesis]. University of Southern California; 2008. [cited 2019 Dec 06]. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/51282/rec/3815.

Council of Science Editors:

West-Wright CN. Lifetime physical activity and its effects on breast cancer survival. [Masters Thesis]. University of Southern California; 2008. Available from: http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/51282/rec/3815

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