+publisher:"University of Saskatchewan" +contributor:("Bharadwaj, Lalita")

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University of Saskatchewan

1. Seitzinger, Patrick J 1992-. Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7958

► Accurate data on the incidence of foodborne illness and food histories for affected individuals represent two important barriers to enteric outbreak surveillance and response. Innovative… (more)

▼ Accurate data on the incidence of foodborne illness and food histories for affected individuals represent two important barriers to enteric outbreak surveillance and response. Innovative tools to collect and analyze this type of public health intelligence will play an important role in research efforts to improve understanding of the extent, impact of and risk factors for foodborne disease in Canada and around the world. Ethica, a smartphone based application used to acquire, store, and analyze data on human behaviour, provided an opportunity to gather information on the occurrence of enteric illness and the food consumption behaviour of 96 university students over a 10-week period. Nausea or vomiting were reported by 34% of participants, and 29% reported diarrhea at least once during the study using at least one of the available reporting options, but only 7% reported they sought medical care. Real-time data collected through digital images, meal descriptions, and microsurveys were used as a reference to measure the sensitivity and specificity of traditional food history questionnaires administered through an email link after 7 or 18 days (2.5 weeks). The validity of food history data collected after 7 days was found to be consequentially low with sensitivities ranging from 14.3% for sprouts to 100% for leafy greens and specificities ranging from 30.4% for beef to 80.4% for peanuts. Similarly, the sensitivities of questions administered after 18 days ranged from 15.8% for sprouts to 77.8% for tomatoes, with specificities ranging from 21.2% for leafy greens to 92.1% for melons. The impact of recall bias on the accuracy of food history data was found to vary with food type. Bayesian latent class analysis was conducted to determine the sensitivities and specificities in the absence of a true gold standard – the results support those of frequentist approach. These findings serve as a first step in measuring the occurrence of self-reported foodborne illness and the implications of recall bias on outbreak investigations so that these biases can be accounted for research and public health practice. Advisors/Committee Members: Martin, Wanda, Tataryn, Joanne, Bharadwaj, Lalita, Schwandt, Michael.

Subjects/Keywords: Field Epidemiology; Foodborne illness; outbreak; recall bias; surveillance; investigation strategies; smartphone; enteric illness; memory bias

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APA (6^th Edition):

Seitzinger, P. J. 1. (2017). Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Seitzinger, Patrick J 1992-. “Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Seitzinger, Patrick J 1992-. “Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies.” 2017. Web. 19 Apr 2021.

Vancouver:

Seitzinger PJ1. Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7958.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Seitzinger PJ1. Addressing Limitations in Foodborne Outbreak Investigation: Recall Bias and the Feasibility of New Surveillance Strategies. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7958

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

2. Ford, Lorelei Lynne 1978-. CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/8309

► Establishing safe drinking water for rural populations dependent on unregulated water is a global challenge. Despite initiatives to improve access to drinking water, hazards associated… (more)

▼ Establishing safe drinking water for rural populations dependent on unregulated water is a global challenge. Despite initiatives to improve access to drinking water, hazards associated with unregulated sources pose a potential risk to human health for rural populations. In the absence of accurate information and monitoring of water quality, consumers form heuristic perceptions of risk associated with their drinking water. Risk perception affects water consumption contributing to uncertainty in risk exposure. Quantifying risk through human health risk assessments (HHRA) has been implemented since the 1940s and advances in risk assessment modeling have created an opportunity to improve HHRA by applying probabilistic Bayesian risk assessment methods. A holistic HHRA integrating risk perception, as it relates to exposure, can quantify uncertainty and provide feedback to improve risk communication and management. The literature lacks a review or summary that characterizes the type and frequency of HHRAs applied to rural populations dependent on unregulated drinking water. The purpose of this thesis is to: (1) summarize studies with HHRA methods applied to unregulated drinking water and rural communities, and describe the characteristics of methods, publications, and current literature gaps; and, (2) characterize and quantify risk perception as it relates to unregulated groundwater wells, and determine the impact of risk perception on human health risk using a holistic HHRA. A systematic scoping review of peer-reviewed literature (Jan 2000 to May 2014) was used to identify studies with HHRAs applied to unregulated or unspecified drinking water. At least one drinking water source was identified as unregulated (21%) or unspecified (79%) in 100 studies, and 7% identified rural communities dependent on unregulated drinking water. No studies integrated non-traditional factors (e.g. risk perception) into a holistic HHRA. HHRAs applied to rural populations dependent on unregulated water are poorly represented in the literature even though almost half of the global population is rural. The scoping review confirmed a lack of HHRA studies addressing unregulated drinking water risks, and the absence of applied methods that facilitated the quantification and integration of non-traditional factors. Based on the review findings, a community-based participatory observational case study and holistic HHRA was applied using arsenic concentrations and survey responses from two communities dependent on unregulated groundwater wells. Risk perception and human health risk was determined using probabilistic (Bayesian) risk assessment methods. Community tap water quality exceeded at least one health standard at a rate of 56% and 65%. Integration of risk perception did not change the overall risk status but lowered the cancer risk for arsenic by 3% for both communities. The probability of exposure to arsenic concentrations over 1:100,000 negligible risk for the two communities was 23% and 22%. There was no correlation between risk perception… Advisors/Committee Members: Bharadwaj, Lalita, Waldner, Cheryl, Feng, Cindy, Lawson, Joshua.

Subjects/Keywords: drinking water; human health risk; Bayesian; probabilistic; arsenic

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APA (6^th Edition):

Ford, L. L. 1. (2017). CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/8309

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ford, Lorelei Lynne 1978-. “CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/8309.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ford, Lorelei Lynne 1978-. “CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES.” 2017. Web. 19 Apr 2021.

Vancouver:

Ford LL1. CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/8309.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ford LL1. CONSUMPTION OF UNREGULATED DRINKING WATER AND HUMAN HEALTH RISK IN RURAL COMMUNTIES. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/8309

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

3. Khare, Nikisha Shally 1993-. COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA.

Degree: 2018, University of Saskatchewan

URL: http://hdl.handle.net/10388/9523

► The practices of Canadian mining companies operating in Latin America, and the Canadian government’s role in supporting these practices, have been duly criticized for the… (more)

▼ The practices of Canadian mining companies operating in Latin America, and the Canadian government’s role in supporting these practices, have been duly criticized for the blatant social, environmental, and economic injustices created and perpetuated by transnational mining. The violation of human and Indigenous rights has elicited widespread resistance to mining from surrounding communities. A considerable amount of literature has explored the dynamics of this anti-mining activism, with most articles exploring a particular case study or feature of a few cases. However, a region-wide systematic synthesis of qualitative themes on the topic has not been found. Given the extent and nature of Canadian mining companies operating Latin America, the purpose of this project was to scope the published literature to characterize the nature of community resistance to Canadian transnational mining in Latin America. A scoping review method was employed to systematically search the literature, select studies for inclusion, chart qualitative data, and synthesize the literature reviewed. After screening, 61 articles discussing a total of 26 conflicts were included in this review. Conflicts in several Latin American countries with various Canadian mining companies were represented in this literature. In 69 percent of conflicts, the literature explicitly states the involvement of Indigenous groups in anti-mining resistance. Seventy-three percent of communities in the 26 conflicts were involved in agricultural livelihood activities. Sixty-five percent of conflicts occurred during the exploration stages of mining with all but one of these communities expressing complete rejections of mining, while 27 percent of conflicts occurred during the exploitation stages of mining with all of these communities seeking to change the conditions under which mining occurred. Communities had several interrelated concerns about mining that motivated their resistance, and used a variety of tactics to enact their activism. Furthermore, only five of 61 articles discussed at length the gendered dimensions of resistance, providing insights into gendered adversities, narratives, and tactics of resistance, and revealing a need for a gendered lens in the study of anti-mining movements. The literature reveals promising and important insights as well as clear gaps in research on the complexity and nuances of anti-mining movements in Latin America. Advisors/Committee Members: Hanson, Lori, Bharadwaj, Lalita, McKenzie, Marcia, Fowler-Kerry, Susan, Jones, Steven.

Subjects/Keywords: activism; mining

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Khare, N. S. 1. (2018). COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/9523

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Khare, Nikisha Shally 1993-. “COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA.” 2018. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/9523.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Khare, Nikisha Shally 1993-. “COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA.” 2018. Web. 19 Apr 2021.

Vancouver:

Khare NS1. COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA. [Internet] [Thesis]. University of Saskatchewan; 2018. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/9523.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Khare NS1. COMMUNITY RESISTANCE TO CANADIAN TRANSNATIONAL MINING OPERATIONS IN LATIN AMERICA. [Thesis]. University of Saskatchewan; 2018. Available from: http://hdl.handle.net/10388/9523

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

4. Daigle, Joanna C 1990-. A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016.

Degree: 2018, University of Saskatchewan

URL: http://hdl.handle.net/10388/8543

► This research aimed to describe temporal patterns in the number and duration of drinking water advisories in Saskatchewan communities on and off reserve from 2012… (more)

▼ This research aimed to describe temporal patterns in the number and duration of drinking water advisories in Saskatchewan communities on and off reserve from 2012 to 2016. The analyses included 445 communities – including cities, towns, villages, and reserves – in which 2036 advisories were in effect. The large sample test of proportion was used to compare the observed proportion of advisories issued which occurred on and off reserve to the expected proportion based upon the proportion of communities which experienced an advisory during the study period that were reserve or non-reserve. Comparisons were also conducted which took into account the size of non-reserve communities, the season advisories were issued, the year advisory were issued, and the community’s geographic region. Descriptive statistics were utilized to describe reasons for issuing advisories. The duration of advisories was investigated using the same comparisons, as well as the reason for issuing advisories, using the Kruskal Wallis and Mann Whitney U Test. Reserve drinking water systems were found to have fewer advisories than would be expected when compared to communities off reserve (p<0.01). Advisories on reserve were longer lasting than those off reserve, the median advisory lasted 14 days on reserve and 9 days for the smallest community type off reserve (villages) (p<0.01). Advisories occurred more often in summer for both reserve and non reserve communities. But while advisories were equivalent in duration across seasons off reserve, advisories issued for reserves were significantly longer if they were issued during the winter(p=<0.02). Advisories were issued more often off reserve for depressurization and equipment issues, while power outages, disinfection failures, contamination, and operation deviation were more common on reserve. The analyses included in this study highlight the acute problem of drinking water on reserve and shows that significant work remains to ensure that all Saskatchewan residents have access to safe, potable drinking water. The use of comparison between reserve and non-reserve communities represents an important step forward towards understanding the extent and causes of drinking water disparities across Saskatchewan. Advisors/Committee Members: Hackett, Paul, Bharadwaj, Lalita, Griebel, Philip, Waldner, Cheryl, Boyd, Greg.

Subjects/Keywords: First Nations; Boil Water Advisories; Small Communities

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Daigle, J. C. 1. (2018). A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/8543

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Daigle, Joanna C 1990-. “A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016.” 2018. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/8543.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Daigle, Joanna C 1990-. “A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016.” 2018. Web. 19 Apr 2021.

Vancouver:

Daigle JC1. A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016. [Internet] [Thesis]. University of Saskatchewan; 2018. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/8543.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Daigle JC1. A COMPARATIVE ANALYSIS OF COMMUNITY WATER SYSTEMS AND DRINKING WATER ADVISORIES ACTIVE IN SASKATCHEWAN COMMUNITIES FROM 2012-2016. [Thesis]. University of Saskatchewan; 2018. Available from: http://hdl.handle.net/10388/8543

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

5. Dhillon, Jasmine M 1974-. Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7688

► Communities employ a wide variety of methods to reduce critical encounters and dog population numbers. However, systematic studies evaluating the success of approaches and techniques… (more)

▼ Communities employ a wide variety of methods to reduce critical encounters and dog population numbers. However, systematic studies evaluating the success of approaches and techniques are currently lacking. Nor has significant consideration of community decision-making processes and policy development, or of the long-term sustainability of these programs been completed. Therefore, to assess the perception of dog-related issues, methods of policy creation and implementation, and true within-community dog demographic characteristics and rate of aggressive encounters a community-based research project was developed. A multiphase, convergent mixed methods study design in four separate northern Saskatchewan communities was implemented to evaluate these concerns. Methods of community-driven policy creation and implementation were recorded, management plans and strategies were monitored, and options were evaluated for successful reduction in dog bites and violent encounters. Community-based participatory methods created exchange and discussion with all levels of society, providing in-depth two-way channels for knowledge translation for researchers and community members. Policy creation and implementation was found to vary significantly between communities. Policies surrounding dog ownership and bite prevention are often dependent upon perceived risks for imminent human-canine aggressive encounters. Regrettably, sustainable interventions require sustained key community partner support and resource access. Community engagement and knowledge translation creates long-term, trusting relationships permitting more in-depth understanding of group choices. In addition, involving community members in research and data collection provides public appreciation of the scope and breadth of community issues and opinions. Enabling and empowering communities entails constant communication and education of all parties. No single model can be effective in all situations. Although enforceable legislation and widespread canine sterilisation are key aspects for community dog issues, comprehensive all-inclusive community education is indispensable. Wide-spread education and communication have the potential to dramatically decrease the number of aggressive dog:human encounters and fulfil goals for dog-human relationships that occur in indigenous communities in Canada. Advisors/Committee Members: Epp, Tasha, Harding, John, Morrison, Karen, Semchuk, Karen, Bharadwaj, Lalita.

Subjects/Keywords: dogs; bites; zoonotic; population management; indigenous; epidemiology

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APA (6^th Edition):

Dhillon, J. M. 1. (2017). Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7688

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Dhillon, Jasmine M 1974-. “Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7688.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Dhillon, Jasmine M 1974-. “Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities.” 2017. Web. 19 Apr 2021.

Vancouver:

Dhillon JM1. Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7688.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Dhillon JM1. Dog Population Management and Dog Bite Prevention in Rural and Remote Northern Saskatchewan Aboriginal Communities. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7688

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

6. Adams, Diane J. First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication.

Degree: 2019, University of Saskatchewan

URL: http://hdl.handle.net/10388/12088

► When issuing drinking water advisories (such as boil water advisories, or BWAs) in First Nations, risk communicators must consider the unique historical, political, social and… (more)

▼ When issuing drinking water advisories (such as boil water advisories, or BWAs) in First Nations, risk communicators must consider the unique historical, political, social and cultural context. A small number of studies have examined risk communication and message mapping in the First Nations context but First Nations drinking water-specific literature is scarce. A community-based participatory research (CBPR) project was conducted with two First Nations and their tribal council in Saskatchewan. The study examined the applicability of risk communication and message mapping in the First Nations context, with the overall goals of improving local risk communication practices and contributing to a First Nations drinking water risk communication framework. Using the Science in a Circle © model, the research partners developed a four-phase CBPR project, rooted in mutual respect for Indigenous and western science worldviews. Through a series of initial community meetings, the research team determined a novel method would be required to investigate boil water advisory communications using culturally appropriate methods. The Participatory Dot-Mapping Method enabled local leaders, experts and everyday community members to participate in all steps of the research process, including data interpretation. Using coloured dots on a map-like response board, participants from each community used coloured dots to note their main concerns, questions and information needs around BWAs. Current and potential BWA communication tactics were also evaluated. Age-coded dot colours showed differences between life stages or age groups. The results suggest effective risk communication must consider factors unique to each community. These include frequency of advisories and preferred methods of communication (e.g. radio, social media, interpersonal communication). Door-to-door flyers and social media alerts were more popular in one community, with youth and/or Elders showing more interest in other electronic alerts (e.g. text, email). Door-to-door flyers and local radio alerts were more popular in the other community. Like non-Indigenous communities, more research is needed to understand how frequency of boil water advisories should inform their communication, and/or what kinds of messages can improve communications of BWAs. Communities should consider health promotion and education activities around BWAs between advisories. Overall, the Science in a Circle © approach and the Participatory Dot-Mapping Method generated actionable local policy knowledge for First Nations and their agencies. Advisors/Committee Members: Bharadwaj, Lalita A, Martin, Wanda, Elias, Brenda, Griebel, Philip, Ramsden, Vivian.

Subjects/Keywords: Indigenous policy; First Nations policy; drinking water management; risk communication; risk perception; boil water advisories; crisis communication; water security; water policy; community-based participatory research; participatory mapping; novel methods; qualitative methods; indigenous research methods; Indigenous research; dotmocracy

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Adams, D. J. (2019). First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/12088

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Adams, Diane J. “First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication.” 2019. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/12088.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Adams, Diane J. “First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication.” 2019. Web. 19 Apr 2021.

Vancouver:

Adams DJ. First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication. [Internet] [Thesis]. University of Saskatchewan; 2019. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/12088.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Adams DJ. First Nations Boil Water Advisories: New Methods and New Approaches for Risk Communication. [Thesis]. University of Saskatchewan; 2019. Available from: http://hdl.handle.net/10388/12088

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

7. McLeod, Lianne M 1967-. Drinking Water in Rural Saskatchewan: Public Perception of Water Quality and Health Risks, and Direct and Indirect Effects of Drinking Water Quality on Chronic Disease.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7789

► In rural areas of Saskatchewan, tap water supplied to houses is not typically tested for quality and safety with the same intensity as public supplies… (more)

▼ In rural areas of Saskatchewan, tap water supplied to houses is not typically tested for quality and safety with the same intensity as public supplies that serve larger populations. Consequently, rural residents might be at greater risk of exposure to poor quality water and any resulting health impacts. The overall objective of this study was to investigate if poor quality water in rural areas was directly or indirectly associated with increased occurrence of diabetes and cardiovascular disease. Perceptions about water quality and safety and how these relate to choices about drinking water among rural Saskatchewan residents were also investigated. Existing water surveillance data from both public water supplies and private wells in SK were summarized using a combination of principal components analysis and geostatistics. The summarized water data were used to estimate regional water quality exposure indicators for use in Bayesian hierarchical models examining ecological associations with health outcomes derived from administrative health data. A quarter of 2065 respondents to a questionnaire sent to rural SK residents reported being unsatisfied with the aesthetic quality of their water, although fewer (12%) believed their water was unsafe to drink. Of the respondents, 31% reported drinking primarily bottled water, while 61% reported drinking tap water at least daily and 48% reported treating their water in the home. The type of water supply along with past experiences and familiarity with the water were consistently associated with risk perception. As expected, perception of quality and risk were important predictors of drinking water choices; aspects of familiarity, experience, and type of water supply were also important. The parameters listed under health standards and aesthetic objectives grouped differently for public water supply and private well data following the application of principal components analysis, suggesting residents using different types of water supplies may be exposed to different patterns of contaminants. Summarizing water quality data through geostatistical models resulted in attenuation of extreme concentrations recorded in the observed data, but appeared to predict trends in water quality that could be useful for prioritizing monitoring efforts and public health messaging about water testing for private wells. Overall, poor groundwater quality was not associated with increased occurrence of diabetes or cardiovascular disease. An increase in principal component scores for public water supplies, characterized mainly by the presence of high levels of hardness and magnesium, was associated with a decrease in the prevalence of ischemic heart disease. This finding was consistent with previously reported results in other regions, and raises the question of whether the in-home treatment of water to remove high mineral content could inadvertently increase the risk of cardiovascular disease. Studies with individual-level exposure measures are recommended to more definitively characterize potential… Advisors/Committee Members: Waldner, Cheryl, Bharadwaj, Lalita, Epp, Tasha, Feng, Cindy, Harding, John.

Subjects/Keywords: water quality; Saskatchewan; rural population; perceptions; drinking water; diabetes; cardiovascular disease; arsenic

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

McLeod, L. M. 1. (2017). Drinking Water in Rural Saskatchewan: Public Perception of Water Quality and Health Risks, and Direct and Indirect Effects of Drinking Water Quality on Chronic Disease. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7789

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McLeod, Lianne M 1967-. “Drinking Water in Rural Saskatchewan: Public Perception of Water Quality and Health Risks, and Direct and Indirect Effects of Drinking Water Quality on Chronic Disease.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7789.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vancouver:

McLeod LM1. Drinking Water in Rural Saskatchewan: Public Perception of Water Quality and Health Risks, and Direct and Indirect Effects of Drinking Water Quality on Chronic Disease. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7789.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McLeod LM1. Drinking Water in Rural Saskatchewan: Public Perception of Water Quality and Health Risks, and Direct and Indirect Effects of Drinking Water Quality on Chronic Disease. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7789

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

8. Guo, Rui. Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution.

Degree: 2013, University of Saskatchewan

URL: http://hdl.handle.net/10388/ETD-2013-03-981

► In this research, a series of synthetically engineered copolymers were synthesized containing polysaccharides (e.g., β-cyclodextrin and chitosan) to address the removal of trihalomethanes (THMs) from… (more)

▼ In this research, a series of synthetically engineered copolymers were synthesized containing polysaccharides (e.g., β-cyclodextrin and chitosan) to address the removal of trihalomethanes (THMs) from water environments. There are two main parts in this research thesis: i) the preparation and characterization of polysaccharide-based copolymers; ii) sorption studies of the copolymers with chloroform and total THMs (TTHMs) in aqueous solution. In the first part of this thesis, grafted polyester, polyester and grafted polyamide copolymers were prepared by cross-linking β-cyclodextrin (β-CD) and chitosan (CS) with various cross-linkers, including poly (acrylic acid) (PAA), terephthaloyl (TCl), and sebacoyl chloride (SCl), respectively. The synthesized copolymer materials were characterized by Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS), Scanning Electron Microscopy (SEM), Thermogravimetric analysis (TGA), Differential scanning calorimetry (DSC), elemental (C and H) analyses, and NMR spectroscopy. Nitrogen porosimetry was used to analyze the surface area and pore structure characteristics of the copolymers and starting materials in solid state. The sorption properties of the copolymers in aqueous solution were studied using different dye probes (e.g., p-nitrophenol and methylene blue) by UV–Vis spectrophotometry. The copolymers showed markedly varied interactions with dye probes in accordance with their composition, surface area, and pore structure characteristics. Diverse materials were afforded by variation of the synthetic conditions. The sorption isotherms were evaluated with various isotherm models (e.g., Langmuir, BET, Freundlich and Sips). The Sips isotherm showed the best overall agreement with the experimental results and the sorption parameters provided estimates of the sorbent surface area and the sorption capacity for various copolymers in aqueous solution. The copolymer sorbents display tunable physicochemical properties according to the synthetic conditions. In the second part of this thesis, the direct aqueous injection (DAI) method with gas chromatography (GC) with electron capture or electrolytic conductivity detectors (ECD) enabled quantitative detection of chloroform and TTHMs in water. A preliminary adsorption study and kinetic study of chloroform provided the information to establish the experimental protocol for the sorption study. The sorption parameters were evaluated using the Sips model. The sorption capacity (Qm) values of chloroform for these synthetically engineered copolymers at similar conditions ranged from 0.00335-1.70 mmol/g. The relative ordering of the Qm values was observed: β-CD/PAA 1:5 > SCl-5 > SCl-10 ~ CP-1 > β-CD/PAA 1:10 > CP-5 > AC > β-CD/PAA 1:5 at high mixing speed. An extension of the sorption study for copolymers toward the multi-component THMs in water was carried out. The copolymers showed distinct adsorption capacities to THMs: chloroform (0.0485-0.287 mmol/g); DBCM (0.0712-0.277 mmol/g); BDCM (0.0684-0.387mmol/g); and bromoform (0.0522-1.07… Advisors/Committee Members: Wilson, Lee D., Bharadwaj, Lalita.

Subjects/Keywords: THMs; Sorption studies; β-CD; Chitosan; Copolymers; GC-ECD; DAI.

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APA (6^th Edition):

Guo, R. (2013). Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2013-03-981

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Guo, Rui. “Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution.” 2013. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/ETD-2013-03-981.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Guo, Rui. “Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution.” 2013. Web. 19 Apr 2021.

Vancouver:

Guo R. Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution. [Internet] [Thesis]. University of Saskatchewan; 2013. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/ETD-2013-03-981.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Guo R. Polysaccharide Materials and Sorption Studies of Chloroform and Total Trihalomethanes (TTHMs) in Aqueous Solution. [Thesis]. University of Saskatchewan; 2013. Available from: http://hdl.handle.net/10388/ETD-2013-03-981

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

9. Ahmed, Asma 1985-. Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7998

► Abstract Background: There is a growing evidence that depression and anxiety disorders have distinct groups of symptom trajectories, which are associated with factors that may… (more)

▼ Abstract Background: There is a growing evidence that depression and anxiety disorders have distinct groups of symptom trajectories, which are associated with factors that may vary among different groups. Studying these mental health trajectories is highly relevant during major life transitions, such as pregnancy and childbirth. The aim of this thesis is to identify subgroups of women who exhibit distinct longitudinal trajectory patterns of depressive and anxiety symptoms from early pregnancy to early postpartum and from pregnancy to five years postpartum and the risk factors associated with these trajectories. Methods: This study uses a longitudinal data collected from 615 women in Saskatchewan, Canada from pregnancy to five years postpartum between 2006 and 2013 (Feelings in Pregnancy and Motherhood (FIP) longitudinal study). The semiparametric group-based modeling strategy was used to identify the latent groups of maternal depressive and anxiety trajectories. Multinomial logit models were then used to explore the association between these latent trajectory groups and various maternal characteristics. Results: Across pregnancy to early postpartum, we identified four trajectory groups of depressive symptoms: low-stable (49.6%); moderate-stable (42.3%); postpartum (3.6%); and antepartum (4.6%), and three latent trajectory groups of anxiety symptoms: very low-stable (8.9%); low-stable (60.7%); and moderate-stable (30.4%). From pregnancy to five years postpartum, four latent trajectory groups of depressive symptoms were identified: low-stable (35.0%); moderate-stable (54.0%); low-rising (5.2%); and high-declining (5.9%), and three latent trajectory groups for anxiety symptoms were identified: very low-stable (13.0%); low-stable (58.1%); and high-stable (29.0%). Several maternal risk factors, most notably past depression and stress level, were associated with these trajectories. Conclusion: Distinct latent trajectory patterns of maternal depressive and anxiety symptoms were identified, which were associated with different profiles of risk factors present prior to or during pregnancy. Our findings support the need for multiple assessments starting from early pregnancy to the postpartum, which may help to recognize women at high risk of major depression or anxiety. All significant risk factors can be identified during regular follow-up and thus, clinicians may be able to identify women at high risk, who may be potential candidates for early interventions that may alter the progress of their mental health symptoms. Advisors/Committee Members: Feng, Cindy, Bowen, Angela, Muhajarine, Nazeem, Haizhen, Mou, Farag, Marwa, Bharadwaj, Lalita, Tikoo, Suresh.

Subjects/Keywords: Longitudinal trajectories; group-based trajectory analysis; maternal depression; maternal anxiety; mood disorders; risk factors.

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APA (6^th Edition):

Ahmed, A. 1. (2017). Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7998

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Ahmed, Asma 1985-. “Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7998.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Ahmed, Asma 1985-. “Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors.” 2017. Web. 19 Apr 2021.

Vancouver:

Ahmed A1. Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7998.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Ahmed A1. Latent Trajectory Groups of Maternal Depressive and Anxiety Symptoms and the Associated Risk Factors. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7998

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

10. Chu, Luan. PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA.

Degree: 2014, University of Saskatchewan

URL: http://hdl.handle.net/10388/ETD-2014-08-1652

► Background & Objectives: There has been few investigation of the association between the farming related activities or specific characteristics and atopic disease in rural Canadian… (more)

▼ Background & Objectives: There has been few investigation of the association between the farming related activities or specific characteristics and atopic disease in rural Canadian children. In population-based studies, assuring the quality of information from questionnaires is of concern. We conducted this study in order to: first, identify the prevalence and risk factors of atopy and allergic conditions among school-age children in a rural region of Canada. Also, we sought to evaluate the validity and reliability of a questionnaire report of allergy to assess in this population. Methods: As part of a longitudinal study of lung health in rural residents, we conducted a cross-sectional baseline study in rural Saskatchewan, Canada. This included an initial survey phase followed by a clinical testing phase. A sub-sample of 584 children (grades 1-8) completed skin prick testing to assess atopic status. Of these, 480 children completed a questionnaire report of allergy and atopic outcomes and participated in skin prick testing (SPT). Atopy was defined as a positive reaction to any of 6 allergens (local grasses, wheat dust, cat dander, house dust mite, Alternaria, Clasdosporium)≥3mm compared to the negative control. Agreement between questionnaire report and objective measures of atopy was considered overall and between the specific allergens tested on SPT and those assessed on questionnaire. We considered percent concordance, Kappa, sensitivity, specificity, and the positive and negative predictive values of reported allergies or allergic conditions in comparison to SPT as the gold standard. Results: The prevalence of atopy as well as allergen-specific sensitizations was similar between farm and non-farm children but supported the notion that livestock farming is protective against atopy. Also, we found that 25.0% of children reported a history of allergic conditions by questionnaire and 19.4% were atopic detected by skin pick test. In our study, the agreement between questionnaire report of specific allergic triggers and atopy measured by SPT was high (83.0% - 89.5%). Conclusion: In children, livestock exposure has a protective effect on SPT positivity.The agreement between questionnaire report of allergic symptoms and atopy measured by SPT was high and the agreement between atopy and report of allergic conditions was moderate. Advisors/Committee Members: Lawson, Joshua A., Rennie, Donna C., Cockcroft, Don, Bharadwaj, Lalita, Abonyi, Sylvia.

Subjects/Keywords: atopy; children; farming exposures; allergic diseases; hay fever; agreement; rural; allergy; spin prick testing; sensitivity and specificity; predictive value

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Chu, L. (2014). PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2014-08-1652

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Chu, Luan. “PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA.” 2014. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/ETD-2014-08-1652.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Chu, Luan. “PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA.” 2014. Web. 19 Apr 2021.

Vancouver:

Chu L. PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA. [Internet] [Thesis]. University of Saskatchewan; 2014. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/ETD-2014-08-1652.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Chu L. PREVALENCE AND DETERMINANTS OF ATOPY AMONG SCHOOL-AGE CHILDREN IN RURAL SASKATCHEWAN, CANADA. [Thesis]. University of Saskatchewan; 2014. Available from: http://hdl.handle.net/10388/ETD-2014-08-1652

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

11. Morrison, Alasdair David 1979-. Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada.

Degree: 2019, University of Saskatchewan

URL: http://hdl.handle.net/10388/12399

► Flooding poses a significant threat to society, a threat that is likely to increase with changing climate. Over recent decades, the limitations of a historical… (more)

▼ Flooding poses a significant threat to society, a threat that is likely to increase with changing climate. Over recent decades, the limitations of a historical reliance on command and control approaches to flood risk management (FRM) have been recognised and scholarly and practical effort has been made towards becoming flood resilient rather than flood resistant. Despite these efforts, the cost of flood events continues to rise. Progressing FRM in a way that increases resilience to flooding requires a better understanding of the challenges that exist when attempting to operationalise theoretical principles of resilience in practice. Empirical studies of FRM implementation, however, are not well represented in the literature. This thesis enhances understanding of the challenges involved in operationalising flood resilience concepts. To achieve this aim, scholarly literature self-identified by the authors as being related to flood risk management, governance and resilience was analysed, and the Prairie Provinces of Canada were utilised as a case study of FRM practice, priorities and preferences. It was found that rather than tackling flood resilience as a defined research topic, FRM and flood resilience research is carried out in specialised disciplinary silos and which does not relate well to the challenges of implementing FRM. Within the Canadian Prairie Provinces, FRM practitioners understand the need for a diverse policy approach to flood risk and for more coordinated and collaborative management; however, challenges from fragmented governance exist in the region including unclear roles and responsibilities, policy conflicts, and inefficiency. Broadly effective emergency planning and response suggests that these challenges are not insurmountable. The FRM priorities of stakeholders are similar across the study area suggesting that there is an underlying foundation for an inter-provincial regional strategy. The heterogeneous policy preferences between provinces and homogenous preferences within provinces, however, present challenges to implementing coordinated multi-level FRM strategies. Importantly, it was found that existing flood policy instruments may not be effective in influencing policy choices, and that innovation is required in this area to progress more resilient FRM. Overall, the findings of this thesis strongly support: the need for close linkages between the academic and practice communities; that research and policy programs should treat FRM as a distinct, holistic, issue, and; that organisations or agencies are needed to facilitate the coordination of stakeholders and resources required to research, manage and continually improve FRM. Advisors/Committee Members: Noble, Bram F, Westbrook, Cherie J, Bharadwaj, Lalita, Patrick, Robert, Strickert, Graham, de Boer, Dirk.

Subjects/Keywords: Flooding; Resilience; Flood Risk Management; Governance

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APA (6^th Edition):

Morrison, A. D. 1. (2019). Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/12399

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Morrison, Alasdair David 1979-. “Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada.” 2019. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/12399.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Morrison, Alasdair David 1979-. “Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada.” 2019. Web. 19 Apr 2021.

Vancouver:

Morrison AD1. Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada. [Internet] [Thesis]. University of Saskatchewan; 2019. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/12399.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Morrison AD1. Moving from Flood Resistance to Resilience: “Still doing it the hard way” in Western Canada. [Thesis]. University of Saskatchewan; 2019. Available from: http://hdl.handle.net/10388/12399

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

12. Vogel, Timothy 1991-. Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations.

Degree: 2019, University of Saskatchewan

URL: http://hdl.handle.net/10388/11772

► Many water systems on First Nations in Saskatchewan are at risk of not being able to consistently meet water quality guidelines, which negatively impacts human… (more)

▼ Many water systems on First Nations in Saskatchewan are at risk of not being able to consistently meet water quality guidelines, which negatively impacts human health. It was the goal of my thesis to assess design and funding methods for water infrastructure projects on First Nations. It was important that this research was informed by community values and priorities gained from discussions with Elders, interviews with water treatment officers, and activities with elementary and high school students. A scoping review looked for existing literature on water infrastructure projects that involved the community in the design process, termed ‘co-design’. Of 1,551 articles searched, only 13 were found using the search terms (and synonyms): “water”, “co-design”, “Indigenous communities”, “infrastructure”, and “Canada”. A common definition of co-design and clear process is required to trend towards community informed design. Co-design as a process for water infrastructure in Indigenous communities encompasses the cultural, traditional, and spiritual values associated with water from the community’s worldview along with the environmental and technical conditions from an engineering standpoint. The increased involvement for this process requires extra funding, which is difficult in communities that are already restricted by rigid funding frameworks. Communities prefer a centralized system (piped water) to reduce the likelihood of contamination and water quantity rationing. The preference for a centralized system is prevented by a funding formula that does not provide the higher capital expense of this infrastructure. However, the formula can be expanded beyond capital investment and regular operation and maintenance to include costs associated with human health. The installation of both decentralized and centralized systems were quoted and compared for an example community of 100 homes (500 people). The approximate capital cost of a centralized system and decentralized system were found to be 3,512,000 and 1,365,000, respectively. However, the extra costs associated with the decentralized system were 570,000 per year, which covers the greater capital investment for a centralized system in under 5 years. The provision of safe drinking water for human health justifies a greater capital investment on its own, but the inclusion of other variables in the funding formula suggests that it is economically feasible as well. Advisors/Committee Members: McPhedran, Kerry, Fonstad, Terry, Bharadwaj, Lalita, Peng, Jian, Boulfiza, Mohamed, Belcher, Ken.

Subjects/Keywords: Drinking water; First Nations

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APA (6^th Edition):

Vogel, T. 1. (2019). Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/11772

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vogel, Timothy 1991-. “Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations.” 2019. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/11772.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vogel, Timothy 1991-. “Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations.” 2019. Web. 19 Apr 2021.

Vancouver:

Vogel T1. Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations. [Internet] [Thesis]. University of Saskatchewan; 2019. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/11772.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vogel T1. Assessing Design and Funding Methods of Water Infrastructure for Saskatchewan First Nations. [Thesis]. University of Saskatchewan; 2019. Available from: http://hdl.handle.net/10388/11772

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

13. Grant, Kellie 1964-. Drinking water source water protection plan implementation: barriers and supports for First Nations.

Degree: 2016, University of Saskatchewan

URL: http://hdl.handle.net/10388/7272

► Access to safe drinking water in First Nations communities is an ongoing problem in Canada with approximately one in five First Nations communities under a… (more)

▼ Access to safe drinking water in First Nations communities is an ongoing problem in Canada with approximately one in five First Nations communities under a drinking water advisory at any one time. The incidence of waterborne illness, resulting from contaminated drinking water, affecting First Nations is more than double that in non-First Nations communities in Canada. Poor source water quality originating from natural conditions is one explanation for this situation; however, other factors also play a role including lack of effective water treatment, lack of water distribution systems, and land use activities and practices that negatively affect source water quality. Sophisticated water treatment and monitoring of treated drinking water is one method to ensure drinking water is safe for human consumption. In contrast, Drinking Water Source Water Protection (DWSWP) takes a preventative approach to the protection of groundwater and surface water used as sources for drinking water. The DWSWP planning process begins with the identification of risks to drinking water sources and ends with plan implementation. In the context of this research, risks are defined as anything that might cause chemical or biological contamination to drinking water sources. The problem is that there has been little research into ensuring that the plans are implemented. This research identified and described 1) the chemical and biological risks to the groundwater source of drinking water in the Muskowekwan First Nation; 2) barriers to First Nations DWSWP plan implementation; and 3) factors supporting First Nations DWSWP plan implementation. Research methods included a literature review to identify institutional arrangements to support DWSWP plan implementation in First Nations. Next, case study research to undertake a DWSWP planning process with Muskowekwan First Nation was undertaken. The case study to identify the chemical and biological risks to the groundwater source of drinking water, develop an implementation strategy for the DWSWP plan and reveal barriers to and opportunities for plan implementation. Semi-structured interviews with key informants were conducted to document existing programs that might support the implementation of DWSWP plans and any known barriers to and supports for DWSWP plan implementation. Interviews also provided data regarding known barriers to the efficient application of these programs for the purposes of DWSWP plan implementation. Document Review, using a set of parameters, was undertaken to analyze the documents associated with the noted programs to identify program accessibility, funding availability, and educational programs and planning tools that might support DWSWP plan implementation. Results indicate that, while programs exist to support First Nations DWSWP plan implementation, dedicated funding is required. Educational opportunities and increased awareness of the importance of DWSWP for those responsible for the provision of safe drinking water in First Nations and better communication… Advisors/Committee Members: Patrick, Robert J, Bharadwaj, Lalita, Hackett, Paul.

Subjects/Keywords: SWP; DWSWP; plan implementation; First Nations; prioritization

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APA (6^th Edition):

Grant, K. 1. (2016). Drinking water source water protection plan implementation: barriers and supports for First Nations. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Grant, Kellie 1964-. “Drinking water source water protection plan implementation: barriers and supports for First Nations.” 2016. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Grant, Kellie 1964-. “Drinking water source water protection plan implementation: barriers and supports for First Nations.” 2016. Web. 19 Apr 2021.

Vancouver:

Grant K1. Drinking water source water protection plan implementation: barriers and supports for First Nations. [Internet] [Thesis]. University of Saskatchewan; 2016. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7272.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Grant K1. Drinking water source water protection plan implementation: barriers and supports for First Nations. [Thesis]. University of Saskatchewan; 2016. Available from: http://hdl.handle.net/10388/7272

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

14. Vold, Lindsey Emily 1989-. A place to cook: A scoping review.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7993

► There has been a growing concern with health equity in public health systems worldwide. It is well known that the primary drivers shaping health are… (more)

▼ There has been a growing concern with health equity in public health systems worldwide. It is well known that the primary drivers shaping health are not medical treatments or genetics, but the conditions in which we live. Conditions, such as food and housing insecurity are pervasive problems in North America, but their relationship is not well understood. While housing and food security remain to be problems in high-income countries, there is minimal research linking the two conditions. The objectives of this research are to identify literature involving housing and food as a means to addressing health inequities and to inform future research. As well, we identify barriers and opportunities on how to address multiple social determinants of health (SDH) from an intersectoral approach. We used Arksey and O’Malley (2005) scoping review design and Dahlgren and Whitehead’s (2007) SDH as a conceptual framework. The most prominent drivers shaping health that are associated with housing and food insecurity are income and material needs, housing status, the built environment, social support networks, and the food environment, but they do not occur in isolation. Three research themes emerged from this review: (1) healthcare access and utilization consequences; (2) typifying the causes and solutions to housing and food insecurity; (2) gaps in research design. There are two emerging challenges to addressing multiple SDH challenges: (a) public health paradigms that frame causes and solutions to health inequalities, and (b) the effect on professional roles, structural-level decision making, and contribution to silo interventions. Opportunities to overcome challenges and advance the SDH agenda are guaranteed income, intersectionality and intersectoral collaboration, and approaching health inequalities with a social justice orientation. Silo interventions are ineffective in achieving health equity and addressing the SDH. Pathways to address food and housing insecurity require coordinated efforts and recognition of the structural determinants guided by political ideology. The task of addressing the SDH in a coordinated way is a daunting mission, given the recognizably challenging domination of the neoliberalism and individualism guiding policy and interventions. However, if reducing inequities is truly a health and population challenge worth striving for, political and structural change is essential. Advisors/Committee Members: Martin, Wanda, Rennie, Donna, Schwandt, Michael, Vandenberg, Helen, Bharadwaj, Lalita.

Subjects/Keywords: Food security; housing; social determinants of health; literature review; public health

…University of Saskatchewan library, were included as searches resources: Public Health Database…

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APA (6^th Edition):

Vold, L. E. 1. (2017). A place to cook: A scoping review. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Vold, Lindsey Emily 1989-. “A place to cook: A scoping review.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vold, Lindsey Emily 1989-. “A place to cook: A scoping review.” 2017. Web. 19 Apr 2021.

Vancouver:

Vold LE1. A place to cook: A scoping review. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7993.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Vold LE1. A place to cook: A scoping review. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7993

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

15. Caldwell, Krystal D 1989-. INFORMATION SEEKING AND SHARING IN RURAL SRI LANKA: IDENTIFICATION OF CENTRAL INDIVIDUALS IN WILDLIFE, LIVESTOCK, AND HUMAN HEALTH INFORMATION NETWORKS.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7740

► Low-resource countries are disproportionately affected by infectious diseases and residents living in rural areas in these countries are more likely to experience geographic or infrastructural… (more)

▼ Low-resource countries are disproportionately affected by infectious diseases and residents living in rural areas in these countries are more likely to experience geographic or infrastructural barriers that limit their access to formal health care or information. For health interventions in these areas to be most effective, information should be tailored for their audience and then disseminated through relevant communication channels. Interventions that utilize existing social networks and that learn about how their audiences talk about the topic of interest are more effective than those that do not. This thesis used a case study in Sri Lanka to 1) identify central actors in wildlife, livestock, and human health information networks and 2) to examine themes and topics that arise during discussions about wildlife, livestock, and human health. One-hundred and forty-three rural residents were interviewed to identify their main sources of wildlife, livestock, and human health information and to identify to whom they would report these health issues. Social network analysis of the responses revealed that government agency staff, such as the Grama Niladhari and government physicians, were the most frequently cited source of wildlife and human health information and the most common place to report health cases. A local indigenous healer was the most common source of livestock health information, the most common person to report livestock health cases to, and best positioned in each of the health networks to disseminate information and receive reports within the community. Women were more likely to be unsure of who to talk to and were considerably less likely to be nominated as a source of health information than men. Locally relevant and central leaders that are seen as key contacts for wildlife, livestock, and human health issues should be engaged and used to effectively disseminate information to and from the community. Government agencies should also engage with and maintain relationships with rural communities to facilitate information sharing. The gender differences shed light on the importance of engaging and accommodating all groups within a Sri Lankan community, perhaps by identifying group-specific opinion leaders that will appropriately communicate information to and from the group. To learn about health discussion topics, a structural topic model was used to identify main topics that emerged in 7,412 survey responses and to examine gender differences among the topics. Seven topics were identified by the topic model: 1) Cost/benefits of living near forest, 2) Reporting/asking about animal health, 3) Diseases caused by animals, 4) Wildlife visits and consequences, 5) Issues and needs of the village, 6) Village societies, and 7) medicine. There were small but significant gender differences for Topics 1-6 which indicated that men and women were spending different amounts of time on different topics. However, given the small gender effect sizes, which ranged from 0.3%-1.6%, it was concluded that gender has a… Advisors/Committee Members: Brook, Ryan, Clark, Doug, Stephen, Craig, Bharadwaj, Lalita, Krogman, Naomi.

Subjects/Keywords: social network analysis; Sri Lanka; health; disease surveillance; topic model

…style thesis as outlined by the University of Saskatchewan College of Graduate Studies and…

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APA (6^th Edition):

Caldwell, K. D. 1. (2017). INFORMATION SEEKING AND SHARING IN RURAL SRI LANKA: IDENTIFICATION OF CENTRAL INDIVIDUALS IN WILDLIFE, LIVESTOCK, AND HUMAN HEALTH INFORMATION NETWORKS. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7740

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Caldwell, Krystal D 1989-. “INFORMATION SEEKING AND SHARING IN RURAL SRI LANKA: IDENTIFICATION OF CENTRAL INDIVIDUALS IN WILDLIFE, LIVESTOCK, AND HUMAN HEALTH INFORMATION NETWORKS.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7740.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vancouver:

Caldwell KD1. INFORMATION SEEKING AND SHARING IN RURAL SRI LANKA: IDENTIFICATION OF CENTRAL INDIVIDUALS IN WILDLIFE, LIVESTOCK, AND HUMAN HEALTH INFORMATION NETWORKS. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7740.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Caldwell KD1. INFORMATION SEEKING AND SHARING IN RURAL SRI LANKA: IDENTIFICATION OF CENTRAL INDIVIDUALS IN WILDLIFE, LIVESTOCK, AND HUMAN HEALTH INFORMATION NETWORKS. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7740

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

16. Zee, Jenna. Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus).

Degree: 2016, University of Saskatchewan

URL: http://hdl.handle.net/10388/ETD-2016-03-2498

► Sturgeon are an ancient family of fish which have remained essentially unchanged for 200 million years, rendering them physiologically distinct from the more modern teleosts.… (more)

▼ Sturgeon are an ancient family of fish which have remained essentially unchanged for 200 million years, rendering them physiologically distinct from the more modern teleosts. Of the 26 known species of sturgeons all are likely endangered. North American populations have been declining steadily since the 1800s due to factors such as overharvesting, habitat alterations and increasing pollution. White sturgeon (Acipenser transmontanus), endemic to Western North America, are the largest freshwater fish on the continent. Protecting white sturgeon is of interest because nearly all Canadian populations are endangered and they are culturally and economically important. Factors such as great size, longevity, position in the food chain and benthic life style render white sturgeon particularly susceptible to bioaccumulation of toxicants. They are known to be among the most sensitive species to pollutants such as metal ions, dioxin-like compounds and endocrine disrupters. However, little is known about their susceptibility to other priority contaminants such as selenium (Se). Selenium, in its organic form selenomethionine (SeMet) has become a contaminant of particular concern as it is a known toxicant that efficiently bioaccumulates and biomagnifies in the food chain. It is also of interest as Se is an essential micronutrient that becomes toxic at only marginally greater than optimal doses. Current elevated concentrations of SeMet in white sturgeon prey, with predicted increases in anthropogenic releases, have made it a contaminant of concern for this species. It is hypothesized that increased releases of Se to aquatic environments have contributed in part to sturgeon declines; however, to date little is known about its specific effects on this species. Therefore, the purpose of the present study was to investigate the sensitivity of three year old white sturgeon to dietary SeMet and to link physiological effects to key molecular events of toxicity and to elucidate the mechanism of toxicity. Specifically, this thesis focused on oxidative stress in liver tissue as a hypothesized primary mechanism of toxicity. For 72 days sturgeon were given either a control diet of 1.4 µg Se/g feed or a diet spiked with SeMet (5.6, 22.4 or 104.4 µg Se/g feed dry mass). These doses corresponded to an uptake necessary for proper health, two environmentally relevant exposures, and a worst-case scenario for industrial Se release, respectively. A subsample of fish was taken at day 10 to investigate molecular endpoints. Within 10 days of exposure, pathological effects were observed in fish given the high dose. Occurrence of severe edema causing exophthalmos developed within 15, 23 and 52 days in high, medium and low dose group fish, respectively. There was a 54% and 22% occurrence of lethal effects in the high and medium dose groups, respectively. Se accumulated in a dose dependent manner and reached equilibrium in high dose fish after approximately 40 days. Growth, liver weight and hepatosomatic index were all significantly lower in the high dose… Advisors/Committee Members: Hecker, Markus, Liber, Karsten, Jardine, Tim, Bharadwaj, Lalita.

Subjects/Keywords: Selenium; aquatic toxicology; sturgeon; fish; histology; oxidative stress

…x28;University of Saskatchewan), Danielle Gagnon (University of Saskatchewan)… …and Markus Hecker (University of Saskatchewan). The tables, figures and references…

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APA (6^th Edition):

Zee, J. (2016). Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus). (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2016-03-2498

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Zee, Jenna. “Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus).” 2016. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/ETD-2016-03-2498.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Zee, Jenna. “Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus).” 2016. Web. 19 Apr 2021.

Vancouver:

Zee J. Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus). [Internet] [Thesis]. University of Saskatchewan; 2016. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/ETD-2016-03-2498.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Zee J. Adverse Health Effects of Dietary Selenomethionine on Juvenile White Sturgeon (Acipenser transmontanus). [Thesis]. University of Saskatchewan; 2016. Available from: http://hdl.handle.net/10388/ETD-2016-03-2498

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

17. Cronmiller, Joshua 1989-. THE VALUE-ADDED OF ENVIRONMENTAL MONITORING FOR CUMULATIVE EFFECTS MANAGEMENT AND DECISION-MAKING IN THE LOWER ATHABASCA PLANNING REGION OF ALBERTA, CANADA.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/8202

► There has emerged in recent years a general consensus that anthropogenic development, including energy resource extraction, agriculture, and urban expansion, pose significant threats to water… (more)

▼ There has emerged in recent years a general consensus that anthropogenic development, including energy resource extraction, agriculture, and urban expansion, pose significant threats to water security and the health of watersheds in Canada. A component of identifying and managing the cumulative effects (CE) of this development is data from short and long-term monitoring programs to support decisions about water use and development. However, attention to CE management is often short-lived, and is exacerbated by the fragmented nature of monitoring data and programs. It is therefore important to understand unsuccessful CE efforts of the past to help determine features of future CE monitoring. In addition, it is often argued that CE management is ineffective due to challenges associated with institutional and organizational arrangements for mobilizing CE monitoring with decision-making. This thesis explores whether and how current environmental monitoring programs and organizations support CE management for land-use decision-making. The research is conducted in the Lower Athabasca planning region of Alberta, Canada, where a variety of industrial activities, a CE approach to decision-making, and a variety of monitoring efforts are ongoing. First, this thesis presents a review of the past and present monitoring programs, identifying reoccurring themes in the failure of monitoring programs, and deriving lessons for other jurisdictions. It then explores the task of integrating environmental monitoring with CE management and decision-making based on semi-structured interviews with CE monitoring professionals, to understand perspectives on the current state-of-practice while considering other options. Results show that three approaches exist for this integration: a distributed monitoring system, a one-window system, and an independent exploratory system. Each system has its own strengths and weaknesses, and the decision to implement any one system depends on the purpose of existing monitoring; the credibility and depth of understanding of region-specific scientific underpinnings; and the needs of CE decision-making. Instead of being susceptible to shorter-term institutional change, monitoring expectations should be guided by the immediate and longer-term needs of decision-making, and supported, implemented, and maintained by credible science. Monitoring to advance CE practice should therefore be the ongoing product of cohesive CE visioning, with oversight from independent scientific efforts. Advisors/Committee Members: Noble, Bram, Patrick, Robert, Belcher, Kenneth, Bharadwaj, Lalita.

Subjects/Keywords: Environmental Monitoring; Cumulative Effects; Decision-Making

…accessed through the University of Saskatchewan library. Due to the nature of regional monitoring…

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APA (6^th Edition):

Cronmiller, J. 1. (2017). THE VALUE-ADDED OF ENVIRONMENTAL MONITORING FOR CUMULATIVE EFFECTS MANAGEMENT AND DECISION-MAKING IN THE LOWER ATHABASCA PLANNING REGION OF ALBERTA, CANADA. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/8202

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cronmiller, Joshua 1989-. “THE VALUE-ADDED OF ENVIRONMENTAL MONITORING FOR CUMULATIVE EFFECTS MANAGEMENT AND DECISION-MAKING IN THE LOWER ATHABASCA PLANNING REGION OF ALBERTA, CANADA.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/8202.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Vancouver:

Cronmiller J1. THE VALUE-ADDED OF ENVIRONMENTAL MONITORING FOR CUMULATIVE EFFECTS MANAGEMENT AND DECISION-MAKING IN THE LOWER ATHABASCA PLANNING REGION OF ALBERTA, CANADA. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/8202.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cronmiller J1. THE VALUE-ADDED OF ENVIRONMENTAL MONITORING FOR CUMULATIVE EFFECTS MANAGEMENT AND DECISION-MAKING IN THE LOWER ATHABASCA PLANNING REGION OF ALBERTA, CANADA. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/8202

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

18. Awoyera, Olasoji Olakunle 1974-. ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES.

Degree: 2018, University of Saskatchewan

URL: http://hdl.handle.net/10388/8491

► There are a number of studies that investigate the association between endotoxin and respiratory outcomes, but few examine ambient endotoxin particularly in smaller industrial cities… (more)

▼ There are a number of studies that investigate the association between endotoxin and respiratory outcomes, but few examine ambient endotoxin particularly in smaller industrial cities in Canada. In epidemiological studies of respiratory diseases, environmental factors are of major concern to health. The aims of this study are: (1) to assess ambient endotoxin levels in two communities in southern Saskatchewan (SK), Canada; and (2) to examine the association between ambient endotoxin levels and forced expiratory volume in one second (FEV1) among older adult residents of the two communities. This work is part of the larger Air Quality and Lung Health Study conducted in the cities of Estevan and Swift Current, SK. Ambient environmental and personal respiratory health measures were collected in three periods (phases) of three month durations. To assess ambient endotoxin levels in the two communities, samples were collected in spring 2013 (Phase 1), fall 2013 (Phase 2), and spring 2014 (Phase 3). The phase sampling strategy was employed to account for potential seasonal variations in endotoxin. Consecutive full-week (7 day accumulation) particle mass size fractions (PM2.5 and PM10) were gravimetrically collected for each of the communities for the 3-month duration of each phase (1-3) and analyzed for endotoxin load (EU/µg) and endotoxin concentration (EU/m3). Geometric means were calculated for endotoxin load and concentration for each particle size fraction (PM2.5 and PM10), each community, and each phase. Differences were tested between particle size fractions, and between communities. The highest levels of endotoxin (EU/µg) found in Estevan were 0.02 (Phase 1), 0.03 (Phase 2) and 0.01(Phase 3), while endotoxin (EU/m3) were 0.04 (Phase 1), 0.07 (Phase 2) and 0.02 (Phase 3). Similar trends were found in Swift Current with 0.04 (Phase 1), 0.10 (Phase 2), and 0.05 (Phase 3) in endotoxin (EU/µg), while 0.07 (Phase 1), 0.13 (Phase 2), and 0.08 (Phase 3) were found in endotoxin (EU/m3). Estevan had no significant differences in endotoxin load (EU/µg) between size fractions for any of the phases. However, endotoxin load was significantly higher in the PM2.5 size fraction as compared to the PM10 for both Phases 2 and 3 for Swift Current. For both communities, in all phases, there was significantly greater endotoxin concentration (EU/m3) in PM2.5 as compared to PM10. Comparing communities, Swift Current had significantly greater endotoxin load (EU/µg) in the PM2.5 size fraction (in all phases) and the PM10 size fractions in Phases 2 and 3 as compared to Estevan. Similar trends were observed for endotoxin concentration (EU/m3) in PM2.5 where mean concentrations were greater in Swift Current as compared to Estevan for all phases, but the difference between communities was significant only in Phase 3 (p<0.0001). For PM10 only in Phase 3 were endotoxin concentrations significantly different between communities with Swift Current having higher mean levels (p<0.02). Endotoxin load and concentration were evaluated… Advisors/Committee Members: Katselis, George, Kirychuk, Shelley, Lawson, Josh, Leis, Anne, Bharadwaj, Lalita.

Subjects/Keywords: Ambient endotoxin; Particulate matter; LAL assay; Outdoor air quality; Rural communities, Adults; Lung function

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Awoyera, O. O. 1. (2018). ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/8491

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Awoyera, Olasoji Olakunle 1974-. “ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES.” 2018. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/8491.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Awoyera, Olasoji Olakunle 1974-. “ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES.” 2018. Web. 19 Apr 2021.

Vancouver:

Awoyera OO1. ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES. [Internet] [Thesis]. University of Saskatchewan; 2018. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/8491.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Awoyera OO1. ENDOTOXIN LEVELS AND THEIR ASSOCIATION WITH RESPIRATORY OUTCOME IN TWO SASKATCHEWAN COMMUNITIES. [Thesis]. University of Saskatchewan; 2018. Available from: http://hdl.handle.net/10388/8491

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

19. Kwiatkowski, Brenda. Stroke in Saskatchewan : a regional sample.

Degree: 2013, University of Saskatchewan

URL: http://hdl.handle.net/10388/ETD-2013-04-1053

► The latest evidence indicates that 50,000 Canadians will experience a stroke in 2013. The hospital care, rehabilitation, and long term care associated with a stroke… (more)

▼ The latest evidence indicates that 50,000 Canadians will experience a stroke in 2013. The hospital care, rehabilitation, and long term care associated with a stroke places a significant burden on our health care system. Lost productivity and premature death have an immeasurable impact on communities in our province as well as the rest of the country. Small, less populated regions such as Saskatchewan may be underrepresented in national data utilized in the development of national prevention and treatment strategies across the country. The absence of local research has necessitated the use of national information to guide prevention, treatment education and programming in Saskatchewan. The goals of this study was to provide a descriptive profile of stroke and transient ischemic attack cases admitted to Royal University Hospital over the period of April 1, 2009 to March 31st, 2010 and to assess the acute management of these cases as defined in the Canadian Best Practice Recommendations for Stroke Care (Strategy, 2010). A randomized sample of 200 cases 55 years and older was selected for a retrospective descriptive study involving review of adult stroke case records. Personal demographics and healthcare performance through the use of measures provided in The Canadian Best Practice Recommendations for Stroke Care (Canadian Stroke Network (CSN) and Heart and Stroke Foundation of Canada (HSFC), 2010) were evaluated. The results indicated many similarities to available national information on type of stroke, risk factors, gender, and age. Hospital adherence to national guidelines comparing selected indicators was exceeded in some areas, and met in most. The remaining indicators provide an opportunity for improvement and possibly more research. This regional information supplements the available Canadian information and could be used to guide planning and care strategically targeting Saskatchewan residents and increasing their potential for success. Advisors/Committee Members: Bharadwaj, Lalita, Rennie, Donna, Teare, Gary, Davison, Joyce.

Subjects/Keywords: stroke; Saskatchewan; regional population; ischemic stroke; transient ischemic attack

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APA (6^th Edition):

Kwiatkowski, B. (2013). Stroke in Saskatchewan : a regional sample. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2013-04-1053

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Kwiatkowski, Brenda. “Stroke in Saskatchewan : a regional sample.” 2013. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/ETD-2013-04-1053.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Kwiatkowski, Brenda. “Stroke in Saskatchewan : a regional sample.” 2013. Web. 19 Apr 2021.

Vancouver:

Kwiatkowski B. Stroke in Saskatchewan : a regional sample. [Internet] [Thesis]. University of Saskatchewan; 2013. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/ETD-2013-04-1053.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Kwiatkowski B. Stroke in Saskatchewan : a regional sample. [Thesis]. University of Saskatchewan; 2013. Available from: http://hdl.handle.net/10388/ETD-2013-04-1053

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

20. Bermedo-Carrasco, Silvia R. 1977-. CERVICAL CANCER INEQUITIES IN COLOMBIA.

Degree: 2017, University of Saskatchewan

URL: http://hdl.handle.net/10388/7748

► Cervical cancer (CC) is the second most common cancer and third in cancer-related deaths among women. Developing countries account for most CC-related deaths and are… (more)

▼ Cervical cancer (CC) is the second most common cancer and third in cancer-related deaths among women. Developing countries account for most CC-related deaths and are highly impacted by CC mortality in young women. In South America, CC is the second most incident cause of cancer and first cause of cancer deaths among women 15-44 years. In Colombia, CC is the second most common cause of cancer mortality among women. Previous studies conducted in Colombia have shown inequities in CC prevention and mortality by different socio- demographic factors; however, there is a lack of nationwide studies evaluating these factors specifically in young Colombian women. The goal of this thesis was to identify socio-demographic characteristics associated with awareness of CC primary prevention, access to secondary prevention for CC, and CC mortality among young women in Colombia. The educational level, type of health insurance, having a rural or urban residence, and region of residence of women were common factors related to inequities in CC prevention and mortality in Colombia. Women with limited or no education had a reduced probability of having heard of HPV vaccination, with differing effects of education by age and region of residence. In the case of Pap testing, having a rural residence decreased the odds of Pap testing compared to having an urban residence, with wider differences in the odds among women with limited-to-no education compared to those with higher education. Additionally, a higher prevalence of no education in the neighbourhood where women lived resulted in lower odds of Pap testing in both rural and urban areas, especially when comparing women with limited-to-no education to women with a secondary or higher education. Measured at the administrative divisions or department level, a high prevalence of no education was associated with a low prevalence of Pap testing, specifically for departments being at or above the national prevalence of women living in rural areas. Similarly, mortality rates were higher among women with limited or no education compared to women with higher education, observing wider differences in younger age groups. Having subsidised insurance and not having insurance were associated with a decreased awareness of HPV vaccination. The effect of type of health insurance on Pap testing varied by whether women had a rural or urban residence. Departments with higher prevalences of women with subsidised insurance were associated with not having heard of HPV vaccination and not having had a Pap test. No significant differences in CC mortality were observed between women with subsidised insurance and those with no insurance. Also, mortality rates for different types of health insurance varied for some age groups. Women living in rural areas had a reduced awareness of HPV vaccination with variations by regions. Having a rural residence also decreased the probability of having Pap testing, particularly in some regions of Colombia and among women with no insurance or subsidised health insurance.… Advisors/Committee Members: Waldner, Cheryl L, Bharadwaj, Lalita, Farag, Marwa, D' Arcy, Carl, Szafron, Michael.

Subjects/Keywords: Cervical cancer prevention; Inequities; Educational Status; Rural Population; Pap test; Papillomavirus vaccines; Mortality; Colombia

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APA (6^th Edition):

Bermedo-Carrasco, S. R. 1. (2017). CERVICAL CANCER INEQUITIES IN COLOMBIA. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/7748

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Bermedo-Carrasco, Silvia R 1977-. “CERVICAL CANCER INEQUITIES IN COLOMBIA.” 2017. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/7748.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Bermedo-Carrasco, Silvia R 1977-. “CERVICAL CANCER INEQUITIES IN COLOMBIA.” 2017. Web. 19 Apr 2021.

Vancouver:

Bermedo-Carrasco SR1. CERVICAL CANCER INEQUITIES IN COLOMBIA. [Internet] [Thesis]. University of Saskatchewan; 2017. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/7748.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Bermedo-Carrasco SR1. CERVICAL CANCER INEQUITIES IN COLOMBIA. [Thesis]. University of Saskatchewan; 2017. Available from: http://hdl.handle.net/10388/7748

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

21. Das, Apurba. Characterizing ice cover behaviour along the Slave River.

Degree: 2015, University of Saskatchewan

URL: http://hdl.handle.net/10388/ETD-2015-06-2105

► River ice is an important component of the traditional way of life for the communities along the Slave River both culturally and economically. During the… (more)

▼ River ice is an important component of the traditional way of life for the communities along the Slave River both culturally and economically. During the winter, a stable ice cover provides local residents with safe access to their traditional hunting, trapping, and fishing grounds along the river. Periodic spring ice breakup flooding is required to maintain the ecological balance along the Slave River Delta. Recently, however, local observations have indicated changes in ice cover characteristics (e.g. air pocket formation, double layer ice, ice cover flooding) during the winter, which increase the risks of travelling on the ice. Also prolongs dry periods during the spring are leading to rapid growth of invasive vegetation that reduces the lake and channel areas of the Delta. Although some attempts have been made to understand the patterns of spring flood frequency in the Delta, very little is known about the Slave River’s ice cover characteristics and behaviour. Remote sensing techniques and field surveys were used in this study to understand the ice cover progression and to examine ice cover characteristics along the river during the winters of 2013-2014 and 2014-2015. RADARSAT-2 satellite imagery captured the changes in the ice cover and identified different types of ice during the winter seasons at two primary study sites – downstream of Fort Smith and the Slave River Delta. The mechanism of ice cover growth, with the formation of air pockets and layers underneath the ice cover was investigated. Steeper channels and several open water sections appear to be contributing to significant amounts of air entrainment into the water in winter. Changes in the hydraulic characteristics due to flow regulation and ice cover progression can also change the quantity and distribution of air pockets along the river ice cover. Additionally, the impact of flow fluctuations on the ice cover (e.g. ice cover flooding) was also observed. Increases in discharge cause the ice cover to crack or dislodge from the river banks, leading to water seeping onto the ice and flooding it, which has implications for the muskrat and beaver populations. A geospatial model was developed to determine the spatial patterns of ice cover breakup along the river from Fort Fitzgerald to the delta. This model successfully identified the areas of breakup initiation and persistence of ice until the end of the breakup. MODIS satellite imagery was used to describe the temporal patterns and evolution of breakup events between the years 2008 and 2011. In addition to geomorphological influences, air temperature and flow conditions also have strong impacts on the spatial and temporal patterns of the ice cover breakup. Advisors/Committee Members: Lindenschmidt, Karl-Erich, Jones, Paul, Kells, James A., Bharadwaj, Lalita, Boer, Dirk H..

Subjects/Keywords: River Ice; Satellite Imagery; Slave River; Geospatial Modeling

…Graduate Studies and Research, University of Saskatchewan. The thesis combines three manuscripts…

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APA (6^th Edition):

Das, A. (2015). Characterizing ice cover behaviour along the Slave River. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/ETD-2015-06-2105

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Das, Apurba. “Characterizing ice cover behaviour along the Slave River.” 2015. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/ETD-2015-06-2105.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Das, Apurba. “Characterizing ice cover behaviour along the Slave River.” 2015. Web. 19 Apr 2021.

Vancouver:

Das A. Characterizing ice cover behaviour along the Slave River. [Internet] [Thesis]. University of Saskatchewan; 2015. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/ETD-2015-06-2105.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Das A. Characterizing ice cover behaviour along the Slave River. [Thesis]. University of Saskatchewan; 2015. Available from: http://hdl.handle.net/10388/ETD-2015-06-2105

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

22. Gunness, Patrina. The effect of 2,4-D on gene expression in cultured cells.

Degree: 2007, University of Saskatchewan

URL: http://hdl.handle.net/10388/etd-10152007-154415

► The cytotoxic effects of exposure to low concentrations of the herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D) that are typically found in groundwater were investigated, in vitro. Most… (more)

▼ The cytotoxic effects of exposure to low concentrations of the herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D) that are typically found in groundwater were investigated, in vitro. Most 2,4-D toxicology studies use high concentrations of the herbicide that are above those typically found in groundwater and measure overt biological endpoints. In contrast, this thesis examines the effects of low concentrations of 2,4-D and measures more subtle and sensitive endpoints such as gene expression and the generation of reactive oxygen species. This work derives from recent cDNA microarray analysis conducted in our laboratory that revealed significant alterations in the expression of 238 genes in cells exposed to nanomolar (nM) concentrations of a commercial formulation of 2,4-D. These findings are extended in this thesis to include the in vitro cytotoxic effects of low concentrations of both technical and commercial 2,4-D on two cell lines. Cells derived from liver (HepG2) and kidney (HEK293) respectively, were chosen, since liver and kidney are known to metabolize 2,4-D in vivo. Cell viability was measured using the Resazurin assay, reactive oxygen species (ROS) were measured with 2’,7’-dichlorofluorescin diacetate (2’,7’-DCFH-DA), and real time–polymerase chain reaction (RT-PCR) was used to assess changes in mRNA expression while protein expression was examined by Western blot.Cell viability studies revealed that low environmental concentrations (0.1 to 100 nM) of 2,4-D induced small, but statistically significant decreases in cell viability. No concentration or time-dependent decreases in cell viability were observed in cells exposed to either forms of low environmental 2,4-D concentrations. HEK293 cells were more susceptible than HepG2 cells to the toxic effects of both forms of 2,4-D, having statistically significant lower viability at all exposure concentrations and durations. Both forms of 2,4-D reduced cell viability in both cell lines, suggesting that cytotoxicity was induced directly by 2,4-D, and not by the ‘inert ingredients’ in the commercial formulation.The ROS assays illustrated that 2,4-D induced statistically significant ROS production in HepG2 and HEK293 cell cultures at concentrations greater than 10 µM and 100 nM respectively. This was both a concentration and time-dependent effect in both cell lines. Although HEK293 cells were more susceptible to 2,4-D, they had 50 to 70% less ROS production than HepG2 cells, at all exposure concentrations and times.The RT-PCR and Western blot analyses showed that exposure of HepG2 and HEK293 cells to low 2,4-D concentrations induced (< 2 fold) alterations in mRNA and protein levels of FTL, FTH1 and PCNA however these changes did not consistently vary with concentration.Taken together, cell viability, ROS and gene expression studies show that low environmental 2,4-D concentrations induced subtle in vitro cytotoxic effects. However we have no evidence that these subtle changes pose a serious health threat to exposed humans. Advisors/Committee Members: Ovsenek, Nicholas (Nick), Bharadwaj, Lalita, Nichol, Helen, Desautels, Michel, Blakley, Barry R..

Subjects/Keywords: HepG2; HEK293; groundwater; gene expression; 2 4-dichlorophenoxyacetic acid; cytotoxicity

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Gunness, P. (2007). The effect of 2,4-D on gene expression in cultured cells. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-10152007-154415

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Gunness, Patrina. “The effect of 2,4-D on gene expression in cultured cells.” 2007. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/etd-10152007-154415.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Gunness, Patrina. “The effect of 2,4-D on gene expression in cultured cells.” 2007. Web. 19 Apr 2021.

Vancouver:

Gunness P. The effect of 2,4-D on gene expression in cultured cells. [Internet] [Thesis]. University of Saskatchewan; 2007. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/etd-10152007-154415.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gunness P. The effect of 2,4-D on gene expression in cultured cells. [Thesis]. University of Saskatchewan; 2007. Available from: http://hdl.handle.net/10388/etd-10152007-154415

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

23. McGuigan, Claire Frances. Effect of nitrate on human cell lines in culture.

Degree: 2007, University of Saskatchewan

URL: http://hdl.handle.net/10388/etd-08092007-175658

► Nitrate is a ubiquitous drinking water contaminant with potential adverse effects on human health. However, little is known about nitrate toxicity at the cellular and… (more)

▼ Nitrate is a ubiquitous drinking water contaminant with potential adverse effects on human health. However, little is known about nitrate toxicity at the cellular and molecular level. The purpose of this study was to examine the effects of environmentally relevant concentrations of nitrate on cytotoxicity and protein expression in human cell lines. To determine if tissue-specific responses occurred, a human hepatoma cell line (HepG2) and a human embryonic kidney cell line (HEK293) were used. Both potassium and ammonium salts of nitrate were used to determine salt-specific toxicity. Test concentrations of nitrate varied from 1 μg/L to 5000 mg/L. Cells were exposed to a nitrate salt for 24, 48, or 72 hours and then examined for effects on viability (using the Neutral Red assay) or proliferation (using the BrdU ELISA assay). To determine the effects of nitrate on protein expression, levels of PCNA, Hsp70, Hsc70, and VEGF protein were monitored using Western blotting in HepG2 and HEK293 cells exposed to KNO3 or NH4NO3 for 24 hours.Nitrate was cytotoxic to both cell types at high concentrations, with EC50 values between 1557 mg/L – (approximately) 5852mg/L for viability, and ~2.5 mg/L – 3631 mg/L for proliferation. Several EC50 values were not calculable based on the available data, but appeared to be far greater than 5000 mg/L. Ammonium nitrate was generally more toxic than potassium nitrate, and increasing exposure time generally resulted in greater toxicity. The HepG2 and HEK293 cells displayed similar responses for most assays, except the 24 hour KNO3 Neutral Red assay. Here, HEK293 viability increased with increasing KNO3 concentrations, while HepG2 viability decreased. The reason for this finding is unknown, but may involve cell-specific homeostatic mechanisms. A hormetic-like effect was observed in both cell types in several of the proliferation assays; the biological significance of this effect remains unknown.No significant changes in protein expression were observed under these experimental conditions. Some subtle trends were present, such as a slight increase in Hsp70 expression with increasing nitrate concentration in both cell types. In HepG2 cells, PCNA expression increased slightly with increasing nitrate concentrations; however, the opposite effect was observed in HEK293 cells. This may be due to transcriptional or translational regulation.In summary, environmentally relevant concentrations of nitrate did not appear to evoke significant cytotoxicity or changes in protein expression. Cell viability and proliferation effects were observed at higher concentrations of nitrate. Private water supplies may contain nitrate concentrations above the EC50 values in these experiments. More research is required to determine if this poses a direct threat to human health. Advisors/Committee Members: Ovsenek, Nicholas (Nick), Bharadwaj, Lalita, Hiebert, Linda M., Blakley, Barry R..

Subjects/Keywords: cytotoxicity; HepG2; nitrates; protein expression; HEK293; tissue culture

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

McGuigan, C. F. (2007). Effect of nitrate on human cell lines in culture. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-08092007-175658

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McGuigan, Claire Frances. “Effect of nitrate on human cell lines in culture.” 2007. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/etd-08092007-175658.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

McGuigan, Claire Frances. “Effect of nitrate on human cell lines in culture.” 2007. Web. 19 Apr 2021.

Vancouver:

McGuigan CF. Effect of nitrate on human cell lines in culture. [Internet] [Thesis]. University of Saskatchewan; 2007. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/etd-08092007-175658.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McGuigan CF. Effect of nitrate on human cell lines in culture. [Thesis]. University of Saskatchewan; 2007. Available from: http://hdl.handle.net/10388/etd-08092007-175658

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Saskatchewan

24. Duckworth, Shannon Elissa. Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress.

Degree: 2010, University of Saskatchewan

URL: http://hdl.handle.net/10388/etd-01132011-124515

► Several studies have found a positive correlation between hypertension and hyperhomocysteinemia. Increasing evidence implicates oxidative stress as one of the initiating events closely linked to… (more)

▼ Several studies have found a positive correlation between hypertension and hyperhomocysteinemia. Increasing evidence implicates oxidative stress as one of the initiating events closely linked to the homocysteine’s ability to damage endothelium, subsequently causing vascular dysfunction. We previously found that heparin protects cultured endothelial cells from free radical injury and oral heparin at 1 mg/kg/48h prevents venous thrombosis in a rat model in vivo. Our objective was to study the protective effects of oral heparin in a rat model with elevated plasma homocysteine (Hcy) concentrations, and begin to elucidate whether the pathophysiological effects of Hcy are mediated through an oxidative mechanism causing endothelial dysfunction. Elevated plasma Hcy levels were induced by feeding male Wistar Kyoto rats a diet containing an additional 1.7% methionine for 8 weeks. Groups included rats fed additional methionine, methionine plus oral heparin (1 mg/kg/48h by gastric feeding tube), and age-matched controls fed normal rat chow. At the end of 8 weeks of treatment, rats were anesthetized using 1.5% isoflurane in 100% oxygen. Hemodynamics parameters were assessed by inserting a Millar Mikro Tip pressure transducer into the left ventricular chamber and the thoracic aorta. Fasting plasma total Hcy levels were measured using a Hcy immunoassay kit with an Abbott IMx instrument. Malondialdehyde (MDA) concentrations, a lipid peroxidation product and marker for oxidative stress, was measured by a spectrophotometric method in serum and tissue samples. Glutathione (GSH) concentrations, an important antioxidant for low-level oxidative stress was measured by HPLC in plasma and tissues samples. Lastly, tissue samples from each experimental group were stained with the TUNEL method to assess their respective percentage of apoptotic endothelial cells. Results were expressed as mean ± S.E. Unpaired Student’s two-tailed t-test was employed to assess the difference between groups with p < 0.05 considered significant. Plasma Hcy was significantly elevated after 8 weeks in the methionine (7.17 ± 0.46 umol/L) and methionine plus heparin treated rats (7.02 ± 0.40 umol/L) compared to control (5.46 ± 0.36 umol/L). All measures of arterial pressure, systolic (SP) and diastolic pressure (DP) and mean arterial pressure (MAP), were significantly elevated in rats fed the methionine diet without heparin (119.9 ± 3.9 mmHg; 90.3 ± 3.5 mmHg; 97.7 ± 2.9 mmHg, respectively) compared to controls (107.8 ± 2.5 mmHg; 79.2 ± 2.1 mmHg; 88.8 ± 2.2 mmHg, respectively) but not compared to heparin (114.7 ± 3.3 mmHg; 83.4 ± 2.4 mmHg; 93.8 ± 2.7 mmHg, respectively). Left ventricular end diastolic pressure (LVEDP) was significantly elevated with the methionine diet without heparin (14.2 ± 2.5 mmHg) but not with heparin treatment (8.4 ± 1.9 mmHg) versus controls (7.1 ± 1.1 mmHg). Also, left ventricular systolic pressure (LVSP) was significantly elevated in the methionine fed rats after 8 weeks (122.6 ± 3.2 mmHg) compared to controls (112.3. ± 2.9… Advisors/Committee Members: Hiebert, Linda, Lee, Paul, Prasad, Kailash, Desautels, Michel, Fisher, Thomas, Bharadwaj, Lalita.

Subjects/Keywords: heparin; hypertension; homocysteine; glutathione; oxidative stress; apoptosis

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Duckworth, S. E. (2010). Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress. (Thesis). University of Saskatchewan. Retrieved from http://hdl.handle.net/10388/etd-01132011-124515

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Duckworth, Shannon Elissa. “Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress.” 2010. Thesis, University of Saskatchewan. Accessed April 19, 2021. http://hdl.handle.net/10388/etd-01132011-124515.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Duckworth, Shannon Elissa. “Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress.” 2010. Web. 19 Apr 2021.

Vancouver:

Duckworth SE. Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress. [Internet] [Thesis]. University of Saskatchewan; 2010. [cited 2021 Apr 19]. Available from: http://hdl.handle.net/10388/etd-01132011-124515.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Duckworth SE. Effect of oral heparin on homocysteine induced changes in hemodynamic parameters and oxidative stress. [Thesis]. University of Saskatchewan; 2010. Available from: http://hdl.handle.net/10388/etd-01132011-124515

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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