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You searched for +publisher:"University of Otago" +contributor:("Duffull, Stephen"). Showing records 1 – 11 of 11 total matches.

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University of Otago

1. Vajjah, Venkata Pavan Kumar. Application of pharmacometric methods to clinical toxicology studies .

Degree: 2011, University of Otago

 Risk assessment is a fundamental part of clinical toxicology. It is complicated due to a variable time course of clinical effects of drugs in clinical… (more)

Subjects/Keywords: Pharmacometrics; Clinical toxicology; Bayesian analysis

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APA (6th Edition):

Vajjah, V. P. K. (2011). Application of pharmacometric methods to clinical toxicology studies . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/554

Chicago Manual of Style (16th Edition):

Vajjah, Venkata Pavan Kumar. “Application of pharmacometric methods to clinical toxicology studies .” 2011. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/554.

MLA Handbook (7th Edition):

Vajjah, Venkata Pavan Kumar. “Application of pharmacometric methods to clinical toxicology studies .” 2011. Web. 04 Jul 2020.

Vancouver:

Vajjah VPK. Application of pharmacometric methods to clinical toxicology studies . [Internet] [Doctoral dissertation]. University of Otago; 2011. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/554.

Council of Science Editors:

Vajjah VPK. Application of pharmacometric methods to clinical toxicology studies . [Doctoral Dissertation]. University of Otago; 2011. Available from: http://hdl.handle.net/10523/554


University of Otago

2. Korell, Julia. Modelling Red Blood Cell Data .

Degree: 2012, University of Otago

 The overarching aim of this work was to utilise modelling and simulation methodology to obtain a better understanding of clinical data generated from or in… (more)

Subjects/Keywords: lifespan; mathematical model; pharmacometrics; methotrexate; red blood cell; pharmacokinetics

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APA (6th Edition):

Korell, J. (2012). Modelling Red Blood Cell Data . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/2659

Chicago Manual of Style (16th Edition):

Korell, Julia. “Modelling Red Blood Cell Data .” 2012. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/2659.

MLA Handbook (7th Edition):

Korell, Julia. “Modelling Red Blood Cell Data .” 2012. Web. 04 Jul 2020.

Vancouver:

Korell J. Modelling Red Blood Cell Data . [Internet] [Doctoral dissertation]. University of Otago; 2012. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/2659.

Council of Science Editors:

Korell J. Modelling Red Blood Cell Data . [Doctoral Dissertation]. University of Otago; 2012. Available from: http://hdl.handle.net/10523/2659


University of Otago

3. Gulati, Abhishek. Applications of pharmacometric methods to systems pharmacology .

Degree: 2013, University of Otago

 Computational techniques are now being used to simulate virtually every facet of drug discovery and development. Attempts are being made to carry out a full… (more)

Subjects/Keywords: pharmacometrics; systems pharmacology; mathematical modelling; coagulation; pharmacokinetics-pharmacodynamics; enoxaparin; clotting time test; adaptive design; DP-optimality; response surface modelling; proper lumping; identifiability; fibrinogen; Australian elapids

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APA (6th Edition):

Gulati, A. (2013). Applications of pharmacometric methods to systems pharmacology . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/4169

Chicago Manual of Style (16th Edition):

Gulati, Abhishek. “Applications of pharmacometric methods to systems pharmacology .” 2013. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/4169.

MLA Handbook (7th Edition):

Gulati, Abhishek. “Applications of pharmacometric methods to systems pharmacology .” 2013. Web. 04 Jul 2020.

Vancouver:

Gulati A. Applications of pharmacometric methods to systems pharmacology . [Internet] [Doctoral dissertation]. University of Otago; 2013. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/4169.

Council of Science Editors:

Gulati A. Applications of pharmacometric methods to systems pharmacology . [Doctoral Dissertation]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4169


University of Otago

4. Wright, Daniel Frank. Model-based Drug Dosing .

Degree: 2013, University of Otago

 The safe and effective use of medicines requires that prescribers use the right drug for the right patient at the right dose. The choice of… (more)

Subjects/Keywords: warfarin; simvastatin; allopurinol; pharmacokinetics; pharmacodynamics; modelling

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APA (6th Edition):

Wright, D. F. (2013). Model-based Drug Dosing . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/4398

Chicago Manual of Style (16th Edition):

Wright, Daniel Frank. “Model-based Drug Dosing .” 2013. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/4398.

MLA Handbook (7th Edition):

Wright, Daniel Frank. “Model-based Drug Dosing .” 2013. Web. 04 Jul 2020.

Vancouver:

Wright DF. Model-based Drug Dosing . [Internet] [Doctoral dissertation]. University of Otago; 2013. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/4398.

Council of Science Editors:

Wright DF. Model-based Drug Dosing . [Doctoral Dissertation]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4398


University of Otago

5. Lagishetty, Chakradhar. Covariates in Pharmacometrics .

Degree: 2013, University of Otago

 Understanding the variability in drug response forms an important aspect of pharmacometrics. Various biological, statistical, clinical and mathematical concepts need to be considered to reach… (more)

Subjects/Keywords: latent covariate; between subject variability; nuisance covariate; telomere length; single nucleotide polymorphisms; qPCR assay; genotyping; biological age; organ function; Pharmacometrics analysis

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APA (6th Edition):

Lagishetty, C. (2013). Covariates in Pharmacometrics . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/4520

Chicago Manual of Style (16th Edition):

Lagishetty, Chakradhar. “Covariates in Pharmacometrics .” 2013. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/4520.

MLA Handbook (7th Edition):

Lagishetty, Chakradhar. “Covariates in Pharmacometrics .” 2013. Web. 04 Jul 2020.

Vancouver:

Lagishetty C. Covariates in Pharmacometrics . [Internet] [Doctoral dissertation]. University of Otago; 2013. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/4520.

Council of Science Editors:

Lagishetty C. Covariates in Pharmacometrics . [Doctoral Dissertation]. University of Otago; 2013. Available from: http://hdl.handle.net/10523/4520


University of Otago

6. Foo, Lee Kien. Optimal design methods that are robust to uncertainty .

Degree: 2012, University of Otago

 Assumptions are usually made when optimising design for an experiment. Unexpected departure from the assumptions may result in suboptimal design. This thesis aims to address… (more)

Subjects/Keywords: optimal design; pharmacokinetic; adaptive design; sampling windows; cost

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APA (6th Edition):

Foo, L. K. (2012). Optimal design methods that are robust to uncertainty . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/2093

Chicago Manual of Style (16th Edition):

Foo, Lee Kien. “Optimal design methods that are robust to uncertainty .” 2012. Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/2093.

MLA Handbook (7th Edition):

Foo, Lee Kien. “Optimal design methods that are robust to uncertainty .” 2012. Web. 04 Jul 2020.

Vancouver:

Foo LK. Optimal design methods that are robust to uncertainty . [Internet] [Doctoral dissertation]. University of Otago; 2012. [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/2093.

Council of Science Editors:

Foo LK. Optimal design methods that are robust to uncertainty . [Doctoral Dissertation]. University of Otago; 2012. Available from: http://hdl.handle.net/10523/2093


University of Otago

7. Ooi, Qing Xi. Application of pharmacometric methods to understand warfarin dose response .

Degree: University of Otago

 Existing warfarin dosing methods do not accurately predict warfarin maintenance doses for patients in the lower or upper quartile of dose requirements. It was argued… (more)

Subjects/Keywords: warfarin; pharmacokinetics; pharmacodynamics; pharmacometrics; coagulation proteins; clotting factors; factor VII; dose individusalisation

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APA (6th Edition):

Ooi, Q. X. (n.d.). Application of pharmacometric methods to understand warfarin dose response . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/8613

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Ooi, Qing Xi. “Application of pharmacometric methods to understand warfarin dose response .” Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/8613.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Ooi, Qing Xi. “Application of pharmacometric methods to understand warfarin dose response .” Web. 04 Jul 2020.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Ooi QX. Application of pharmacometric methods to understand warfarin dose response . [Internet] [Doctoral dissertation]. University of Otago; [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/8613.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Ooi QX. Application of pharmacometric methods to understand warfarin dose response . [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/8613

Note: this citation may be lacking information needed for this citation format:
No year of publication.


University of Otago

8. Shivva, Vittal. Pharmacometric methods in clinical pharmacology: An application to ketones .

Degree: University of Otago

 Pharmacometric methods have seen increased application in clinical pharmacology in recent years. These methods are applied from the early stages of drug discovery to clinical… (more)

Subjects/Keywords: Pharmacometrics; Pharmacology; Ketones; Identifiability; Systems; models

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APA (6th Edition):

Shivva, V. (n.d.). Pharmacometric methods in clinical pharmacology: An application to ketones . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/5994

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Shivva, Vittal. “Pharmacometric methods in clinical pharmacology: An application to ketones .” Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/5994.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Shivva, Vittal. “Pharmacometric methods in clinical pharmacology: An application to ketones .” Web. 04 Jul 2020.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Shivva V. Pharmacometric methods in clinical pharmacology: An application to ketones . [Internet] [Doctoral dissertation]. University of Otago; [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/5994.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Shivva V. Pharmacometric methods in clinical pharmacology: An application to ketones . [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/5994

Note: this citation may be lacking information needed for this citation format:
No year of publication.


University of Otago

9. Pan, Shan. Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis .

Degree: University of Otago

 Rheumatoid arthritis (RA) is a common inflammatory disease that affects between 0.5% and 1% of adults in developed countries. It is a chronic and progressive… (more)

Subjects/Keywords: pharmacometrics; methotrexate; rheumatoid; arthritis

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APA (6th Edition):

Pan, S. (n.d.). Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/6211

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Pan, Shan. “Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis .” Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/6211.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Pan, Shan. “Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis .” Web. 04 Jul 2020.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Pan S. Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis . [Internet] [Doctoral dissertation]. University of Otago; [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/6211.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Pan S. Application of pharmacometric methods to quantify the effects of methotrexate in rheumatoid arthritis . [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/6211

Note: this citation may be lacking information needed for this citation format:
No year of publication.


University of Otago

10. Al-Sallami, Hesham. Optimising Patient Care by Individualising Drug Dosage .

Degree: University of Otago

 Drug therapy is an important component of the treatment and prevention of diseases. A drug is administered to achieve a treatment target so it is… (more)

Subjects/Keywords: Dose Individualisation; Pharmacometrics; PKPD; Covariates; Enoxaparin; Heparin; Clinical Pharmacology; Fat-free mass; Target-concentration intervention

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APA (6th Edition):

Al-Sallami, H. (n.d.). Optimising Patient Care by Individualising Drug Dosage . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/5787

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Al-Sallami, Hesham. “Optimising Patient Care by Individualising Drug Dosage .” Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/5787.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Al-Sallami, Hesham. “Optimising Patient Care by Individualising Drug Dosage .” Web. 04 Jul 2020.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Al-Sallami H. Optimising Patient Care by Individualising Drug Dosage . [Internet] [Doctoral dissertation]. University of Otago; [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/5787.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Al-Sallami H. Optimising Patient Care by Individualising Drug Dosage . [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/5787

Note: this citation may be lacking information needed for this citation format:
No year of publication.


University of Otago

11. Siripuram, Vijay Kumar. Understanding azathioprine metabolism using a systems pharmacology approach .

Degree: University of Otago

 Quantitative systems pharmacology (QSP) modelling, being an integral part of pharmacometrics, is attracting a great amount of attention in drug development and clinical therapy as… (more)

Subjects/Keywords: Pharmacometrics; Population pharmacokinetics; azathioprine; modelling and simulation; identifiability; simulated annealing; QSP models

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APA (6th Edition):

Siripuram, V. K. (n.d.). Understanding azathioprine metabolism using a systems pharmacology approach . (Doctoral Dissertation). University of Otago. Retrieved from http://hdl.handle.net/10523/9474

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Chicago Manual of Style (16th Edition):

Siripuram, Vijay Kumar. “Understanding azathioprine metabolism using a systems pharmacology approach .” Doctoral Dissertation, University of Otago. Accessed July 04, 2020. http://hdl.handle.net/10523/9474.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

MLA Handbook (7th Edition):

Siripuram, Vijay Kumar. “Understanding azathioprine metabolism using a systems pharmacology approach .” Web. 04 Jul 2020.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Vancouver:

Siripuram VK. Understanding azathioprine metabolism using a systems pharmacology approach . [Internet] [Doctoral dissertation]. University of Otago; [cited 2020 Jul 04]. Available from: http://hdl.handle.net/10523/9474.

Note: this citation may be lacking information needed for this citation format:
No year of publication.

Council of Science Editors:

Siripuram VK. Understanding azathioprine metabolism using a systems pharmacology approach . [Doctoral Dissertation]. University of Otago; Available from: http://hdl.handle.net/10523/9474

Note: this citation may be lacking information needed for this citation format:
No year of publication.

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