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You searched for +publisher:"University of North Carolina" +contributor:("Gracz, Adam David"). One record found.

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University of North Carolina

1. Gracz, Adam David. The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract.

Degree: Cell Biology and Physiology, 2011, University of North Carolina

Stem cell biology, though a well-established concept in the scientific zeitgeist, is only beginning to emerge as an independent field of study. An understanding of basic stem cell biology and its translation into clinically applicable therapies holds the potential to direct a paradigm shift in modern medical practice. However, in order to realize this potential, the scientific community must first understand the genetic and molecular mechanisms by which cells acquire and maintain 'stemness', specifically, multipotency and the ability to self-renew. Studying the transcriptional machinery that controls these properties could lead to a greater understanding of stem cells as a component of physiology as a whole. Due to its critical importance to homeostasis, the gastrointestinal tract is an attractive system for the study of stem cell biology. Sox factors, a group of transcription factors that have previously been associated with embryonic and neural stem cells, are rapidly emerging as central to maintaining 'stemness' in the gastrointestinal tract as well. This work reviews the known role of Sox factors in the gastrointestinal epithelium and describes our novel findings regarding Sox9 as a marker of stem cells in the adult intestinal epithelium. Advisors/Committee Members: Gracz, Adam David, Magness, Scott, Lund, Pauline Kay, University of North Carolina at Chapel Hill.

Subjects/Keywords: School of Medicine; Department of Cell Biology and Physiology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gracz, A. D. (2011). The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:b263fe64-d6f7-4056-90b7-51d43225a651

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Gracz, Adam David. “The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract.” 2011. Thesis, University of North Carolina. Accessed October 27, 2020. https://cdr.lib.unc.edu/record/uuid:b263fe64-d6f7-4056-90b7-51d43225a651.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Gracz, Adam David. “The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract.” 2011. Web. 27 Oct 2020.

Vancouver:

Gracz AD. The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract. [Internet] [Thesis]. University of North Carolina; 2011. [cited 2020 Oct 27]. Available from: https://cdr.lib.unc.edu/record/uuid:b263fe64-d6f7-4056-90b7-51d43225a651.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Gracz AD. The role of Sry-Box (Sox) transcription factors in epithelial stem cell biology of the gastrointestinal tract. [Thesis]. University of North Carolina; 2011. Available from: https://cdr.lib.unc.edu/record/uuid:b263fe64-d6f7-4056-90b7-51d43225a651

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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