+publisher:"University of North Carolina" +contributor:("Cecil, Gerald")

University of North Carolina

1. Osborne, Lukas. Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials.

Degree: Physics and Astronomy, 2015, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:ecab069a-3543-41d9-8a8b-14364ef9b9d3

► Cancer metastasis involves a series of events known as the metastatic cascade. In this complex progression, cancer cells detach from the primary tumor, invade the… (more)

▼ Cancer metastasis involves a series of events known as the metastatic cascade. In this complex progression, cancer cells detach from the primary tumor, invade the surrounding stromal space, transmigrate the vascular system, and establish secondary tumors at distal sites. Specific mechanical phenotypes are likely adopted to enable cells to successfully navigate the mechanical environments encountered during metastasis. To examine the role of cell mechanics in cancer progression, I employed force-consistent biophysical and biochemical assays to characterize the mechanistic links between stiffness, stiffness response and cell invasion during the epithelial to mesenchymal transition (EMT). EMT is an essential physiological process, whose abnormal reactivation has been implicated in the detachment of cancer cells from epithelial tissue and their subsequent invasion into stromal tissue. I demonstrate that epithelial-state cells respond to force by evoking a stiffening response, and that after EMT, mesenchymal-state cells have reduced stiffness but also lose the ability to increase their stiffness in response to force. Using loss and gain of function studies, two proteins are established as functional connections between attenuated stiffness and stiffness response and the increased invasion capacity acquired after EMT. To enable larger scale assays to more fully explore the connection between biomechanics and cancer, I discuss the development of an automated array high throughput (AHT) microscope. The AHT system is shown to implement passive microbead rheology to accurately characterize the mechanical properties of biomaterials. Compared to manually performed mechanical characterizations, the AHT system executes experiments in two orders of magnitude less time. Finally, I use the AHT microscope to study the effect of gain of function oncogenic molecules on cell stiffness. I find evidence that our assay can identify alterations in cell stiffness due to constitutive activation of cancer pathways. Advisors/Committee Members: Osborne, Lukas, Superfine, Richard, Cecil, Gerald, Falvo, Michael, Burridge, Keith, Blobe, Gerard.

Subjects/Keywords: Physics; Biophysics; Biomechanics; College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Osborne, L. (2015). Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:ecab069a-3543-41d9-8a8b-14364ef9b9d3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Osborne, Lukas. “Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials.” 2015. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:ecab069a-3543-41d9-8a8b-14364ef9b9d3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Osborne, Lukas. “Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials.” 2015. Web. 23 Jan 2021.

Vancouver:

Osborne L. Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials. [Internet] [Thesis]. University of North Carolina; 2015. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:ecab069a-3543-41d9-8a8b-14364ef9b9d3.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Osborne L. Biophysics of Cancer Progression and High-Throughput Mechanical Characterization of Biomaterials. [Thesis]. University of North Carolina; 2015. Available from: https://cdr.lib.unc.edu/record/uuid:ecab069a-3543-41d9-8a8b-14364ef9b9d3

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

2. Stark, David. Drivers of Galaxy Fueling.

Degree: Physics and Astronomy, 2015, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:fab33f48-4fa3-4c28-bb2f-4ece34022dc5

► In an effort to clarify the connection between the evolution of galaxies and their surroundings, this work investigates how environment influences the fueling of galaxies.… (more)

▼ In an effort to clarify the connection between the evolution of galaxies and their surroundings, this work investigates how environment influences the fueling of galaxies. We explore when and where environmental mechanisms play a major role in both the conversion of gas into stars and the replenishment of galaxy gas reservoirs over time, as well as the loss of gas due to heating or stripping. We identify multiple connected evolutionary sequences in a fueling diagram that relates global molecular-to-atomic gas ratios and mass-corrected blue-centeredness, a metric tracing the degree to which galaxies have bluer centers than the average galaxy at their stellar mass. Most spiral galaxies follow a positive correlation between global molecular-to-atomic gas ratios and mass-corrected blue-centeredness, suggesting that minor mergers and interactions between galaxies play a systematic role in driving gas inflows that replenish star forming molecular gas. We also identify a population of blue-sequence E/S0 galaxies (with masses below key scales associated with transitions in gas richness) that occupy a distinct regime of the fueling diagram. These galaxies appear to be the result of gas-rich major mergers, and show signs of rebuilding their gas disks through fresh gas accretion as they emerge from their recent central starburst. We next investigate the potential for star formation in the Smith Cloud, a "high-velocity cloud" currently interacting with the Milky Way. This study explores whether low density clouds of gas that serve to refuel the gas reservoirs of galaxies like the Milky Way can themselves be sites of star formation prior to accretion (possibly driven by tidal interactions with their larger host). Finding star formation might also suggest that the Smith Cloud, and potentially other high-velocity clouds, are really dwarf galaxies. We do not identify a statistically significant number of candidate young stars in projection with the cloud. However, we note several striking similarities between the Smith Cloud and the recently discovered galaxy, Leo P, a high velocity cloud with a confirmed stellar population. The young stars in Leo P would not yield a statistically significant detection if Leo P were placed at the Smith Cloud's distance and projected location near the Milky Way, leaving open the possibility that the Smith Cloud may yet prove to be a dwarf galaxy. We conclude by analyzing how how different environmental scales influence the global atomic gas fractions and spectral profiles of galaxies, employing the new ~90% complete RESOLVE atomic gas census and a variety of metrics designed to characterize the local and large-scale environments of galaxies. We show that satellites below M*=10¹⁰ Msun experience gas depletion in moderate-mass (~10¹² Msun) group dark matter halos, well below the scale of massive galaxy groups and clusters. We also identify a significant population of gas-depleted centrals in low mass (<10¹¹.4 Msun) dark matter halos that cluster around more massive groups. This population is… Advisors/Committee Members: Stark, David, Kannappan, Sheila, Cecil, Gerald, Heitsch, Fabian, Henning, Reyco, Reichart, Daniel.

Subjects/Keywords: Astronomy; Astronomy; College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Stark, D. (2015). Drivers of Galaxy Fueling. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:fab33f48-4fa3-4c28-bb2f-4ece34022dc5

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Stark, David. “Drivers of Galaxy Fueling.” 2015. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:fab33f48-4fa3-4c28-bb2f-4ece34022dc5.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Stark, David. “Drivers of Galaxy Fueling.” 2015. Web. 23 Jan 2021.

Vancouver:

Stark D. Drivers of Galaxy Fueling. [Internet] [Thesis]. University of North Carolina; 2015. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:fab33f48-4fa3-4c28-bb2f-4ece34022dc5.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stark D. Drivers of Galaxy Fueling. [Thesis]. University of North Carolina; 2015. Available from: https://cdr.lib.unc.edu/record/uuid:fab33f48-4fa3-4c28-bb2f-4ece34022dc5

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

3. Giovanetti, Graham. P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES.

Degree: Physics and Astronomy, 2015, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:59c611a3-cb9e-45a4-86d9-108afe437683

► In the last two decades, experimental results from the direct detection of solar, reactor, and atmospheric neutrinos have provided convincing evidence that neutrinos have mass,… (more)

▼ In the last two decades, experimental results from the direct detection of solar, reactor, and atmospheric neutrinos have provided convincing evidence that neutrinos have mass, the first definitive evidence of physics beyond the Standard Model. The existence of massive neutrinos opens many questions about the neutrino's intrinsic properties, including the absolute mass, the relative hierarchy of the neutrino mass states, and the Majorana or Dirac nature of the neutrino. The MAJORANA DEMONSTRATOR is an array of p-type point contact (PPC) high purity germanium detectors that will search for the neutrinoless double-beta decay of 76-Ge, a process that can only occur if the neutrino is a Majorana particle. PPC detectors have several characteristics that make them well suited for a 76-Ge neutrinoless double-beta decay search, including sub-keV energy thresholds that allow for background rejection based on low-energy x-ray tagging. This feature makes the MAJORANA DEMONSTRATOR sensitive to signals that might be present from processes that are not in the current Standard Model of particle physics. The MAJORANA Low-background Broad Energy Germanium Detector at KURF (MALBEK) is a PPC detector operated at the Kimballton Underground Research Facility (KURF) in Ripplemead, VA. MALBEK was used to test the stability and performance of PPC detectors and study sources of background near the detector energy threshold. It was found that the dominant background below 1 keV in MALBEK data is due to slow surface events, a class of signals originating from interactions that occur near the detector surface. Techniques were developed for identifying surface events and simulating their formation and distribution. These techniques were then applied to 89.5 kg-d of data and searches were performed for signals from weakly interacting massive particles (WIMPs), solar axions, and Pauli exclusion principle violating electron transitions. No evidence of a signal was found. These results are presented in the context of present and future experiments, including the MAJORANA DEMONSTRATOR. Advisors/Committee Members: Giovanetti, Graham, Wilkerson, John, Cecil, Gerald, Engel, Jonathan, Henning, Reyco, Radford, David.

Subjects/Keywords: Nuclear physics; Particles (Nuclear physics); College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Giovanetti, G. (2015). P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:59c611a3-cb9e-45a4-86d9-108afe437683

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Giovanetti, Graham. “P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES.” 2015. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:59c611a3-cb9e-45a4-86d9-108afe437683.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Giovanetti, Graham. “P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES.” 2015. Web. 23 Jan 2021.

Vancouver:

Giovanetti G. P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES. [Internet] [Thesis]. University of North Carolina; 2015. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:59c611a3-cb9e-45a4-86d9-108afe437683.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Giovanetti G. P-TYPE POINT CONTACT GERMANIUM DETECTORS AND THEIR APPLICATION IN RARE-EVENT SEARCHES. [Thesis]. University of North Carolina; 2015. Available from: https://cdr.lib.unc.edu/record/uuid:59c611a3-cb9e-45a4-86d9-108afe437683

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

4. McBride, JoEllen. Star Formation Histories of Southern Compact Groups.

Degree: Physics and Astronomy, 2016, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:7352b6da-15fd-4737-b9ef-2ee9eaa66125

► Compact group galaxies are a common phase in galaxy evolution and provide insight into the process that transforms galaxies from isolated, star forming late-type galaxies… (more)

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

McBride, J. (2016). Star Formation Histories of Southern Compact Groups. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:7352b6da-15fd-4737-b9ef-2ee9eaa66125

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

McBride, JoEllen. “Star Formation Histories of Southern Compact Groups.” 2016. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:7352b6da-15fd-4737-b9ef-2ee9eaa66125.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

McBride, JoEllen. “Star Formation Histories of Southern Compact Groups.” 2016. Web. 23 Jan 2021.

Vancouver:

McBride J. Star Formation Histories of Southern Compact Groups. [Internet] [Thesis]. University of North Carolina; 2016. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:7352b6da-15fd-4737-b9ef-2ee9eaa66125.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

McBride J. Star Formation Histories of Southern Compact Groups. [Thesis]. University of North Carolina; 2016. Available from: https://cdr.lib.unc.edu/record/uuid:7352b6da-15fd-4737-b9ef-2ee9eaa66125

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

5. Tanner, Ryan. Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas.

Degree: Physics and Astronomy, 2016, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:6bde48c9-1381-4c15-8484-34c6bdec9c73

► My three-dimensional hydro-dynamical simulations of starbursts examine the formation of starburst-driven superbubbles over a range of driving luminosities and mass loadings that determine superbubble growth… (more)

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Tanner, R. (2016). Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:6bde48c9-1381-4c15-8484-34c6bdec9c73

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Tanner, Ryan. “Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas.” 2016. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:6bde48c9-1381-4c15-8484-34c6bdec9c73.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Tanner, Ryan. “Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas.” 2016. Web. 23 Jan 2021.

Vancouver:

Tanner R. Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas. [Internet] [Thesis]. University of North Carolina; 2016. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:6bde48c9-1381-4c15-8484-34c6bdec9c73.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Tanner R. Numerical Models of Starburst Galaxies: Galactic Winds and Entrained Gas. [Thesis]. University of North Carolina; 2016. Available from: https://cdr.lib.unc.edu/record/uuid:6bde48c9-1381-4c15-8484-34c6bdec9c73

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

6. Frazer, Christopher. Gas Dynamics and Star Formation near Supermassive Black Holes.

Degree: Physics and Astronomy, 2018, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:d770193a-f26e-4285-9a56-edb13b3fc3a6

► The existence of young stars in the central parsec of the Milky Way’s Galactic Center (GC) is challenging to explain due to the extreme tidal… (more)

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Frazer, C. (2018). Gas Dynamics and Star Formation near Supermassive Black Holes. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:d770193a-f26e-4285-9a56-edb13b3fc3a6

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Frazer, Christopher. “Gas Dynamics and Star Formation near Supermassive Black Holes.” 2018. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:d770193a-f26e-4285-9a56-edb13b3fc3a6.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Frazer, Christopher. “Gas Dynamics and Star Formation near Supermassive Black Holes.” 2018. Web. 23 Jan 2021.

Vancouver:

Frazer C. Gas Dynamics and Star Formation near Supermassive Black Holes. [Internet] [Thesis]. University of North Carolina; 2018. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:d770193a-f26e-4285-9a56-edb13b3fc3a6.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Frazer C. Gas Dynamics and Star Formation near Supermassive Black Holes. [Thesis]. University of North Carolina; 2018. Available from: https://cdr.lib.unc.edu/record/uuid:d770193a-f26e-4285-9a56-edb13b3fc3a6

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

7. Cheng, Haw. A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II.

Degree: Physics and Astronomy, 2014, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:72cb6722-b5d6-49a8-9bfb-df2548616c07

► A photometric study of the ultra-faint dwarf (UFD) galaxies Leo IV and Boötes II in the V and I[C] filters is here presented. The age… (more)

▼ A photometric study of the ultra-faint dwarf (UFD) galaxies Leo IV and Boötes II in the V and I[C] filters is here presented. The age of Leo IV relative to M92 was derived by fitting of Dartmouth isochrones, by a “standard” V[HB][TO] method, and by the V[HB][TO] method of VandenBerg et al. 2013. The age of Boötes II relative to M92 was derived by fitting of Dartmouth isochrones. Leo IV is found to be between 2 to 2.5 Gyr younger than M92 by these three methods. It is found to be predominantly old and metal poor and is well fit by isochrones of [Fe/H] = -2.46 and [α/Fe] = 0.2 and 0.4. An age spread with a plausible value of ~ 2 Gyr cannot be ruled out. A 10 Gyr old synthetic horizontal branch with [Fe/H] = -1.70 and [α/Fe] of 0.2 is fit to Leo IV’s red horizontal branch (RHB). The good fit of this model and its matching isochrone to Leo IV’s CMD suggests that the RHB is real and not an observational artifact as proposed by Okamoto et al. 2012. Two RR[ab] Lyraes previously observed by Moretti et al. 2009 were observed in Leo IV. One of the stars, V1, is observed to exhibit the Blazhko effect. No further RR Lyraes were uncovered in Leo IV. Comparison of the horizontal branch’s observed V magnitude to the absolute magnitudes of the RR Lyraes yields a distance modulus of (m-M)0 = 21.01 ± 0.07, in good agreement with previous studies. Leo IV’s possible population of blue stragglers is found to show no signs of central concentration, though this study’s sample and spatial coverage are too small for any detailed spatial distribution study. Boötes II’s CMD is found to be consistent with that of a single age, mono-metallicity system. It is well fit by isochrones of [Fe/H] = -1.79 and [α/Fe] = 0.2 and 0.4. Boötes II is found to be between 0.5 to 1.5 Gyr younger than M92. Distance was left as a free parameter in the fits. Boötes II is found to have distance modulus (m-M)0 lying between 18.02 to 18.15, in good agreement with previous studies. A single RRab Lyrae is discovered in Boötes II. Advisors/Committee Members: Cheng, Haw, Carney, Bruce, Cecil, Gerald, Evans, Charles, Karwowski, Hugon, Reichart, Daniel.

Subjects/Keywords: Astronomy; Astronomy; Physics; College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Cheng, H. (2014). A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:72cb6722-b5d6-49a8-9bfb-df2548616c07

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Cheng, Haw. “A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II.” 2014. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:72cb6722-b5d6-49a8-9bfb-df2548616c07.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Cheng, Haw. “A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II.” 2014. Web. 23 Jan 2021.

Vancouver:

Cheng H. A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II. [Internet] [Thesis]. University of North Carolina; 2014. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:72cb6722-b5d6-49a8-9bfb-df2548616c07.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Cheng H. A Photometric Study of the Dwarf Spheroidal Galaxies Leo IV and Boötes II. [Thesis]. University of North Carolina; 2014. Available from: https://cdr.lib.unc.edu/record/uuid:72cb6722-b5d6-49a8-9bfb-df2548616c07

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

8. Buckner, Matthew. Hydrogen Burning of the Rare Oxygen Isotopes.

Degree: Physics and Astronomy, 2014, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:876509f7-86a6-4773-a854-00420c972e7a

► At the Laboratory for Experimental Nuclear Astrophysics (LENA), two rare oxygen isotope proton capture studies were performed at low energies – ¹⁸O(p,γ)¹⁹F and ¹⁷O(p,γ)¹⁸F. The goal… (more)

▼ At the Laboratory for Experimental Nuclear Astrophysics (LENA), two rare oxygen isotope proton capture studies were performed at low energies – ¹⁸O(p,γ)¹⁹F and ¹⁷O(p,γ)¹⁸F. The goal of each study was to improve thermonuclear reaction rates at stellar plasma temperatures relevant to ¹⁸O and ¹⁷O destruction, respectively. The stellar nucleosynthesis temperature regime corresponds to very low proton bombarding energies. At these low energies, the Coulomb barrier suppresses the reaction yield in the laboratory, and environmental backgrounds dominate the detected signal, making it difficult to differentiate the γ-cascade from background. At LENA, the electron cyclotron resonance (ECR) ion source produces intense, low-energy proton beam, and these high currents boost the reaction yield. LENA, a "sea-level" facility dedicated to nuclear astrophysics, also has a coincidence detector setup that reduces environmental background contributions and boosts signal-to-noise. The sensitivity afforded by γγ-coincidence and high beam current allowed these rare oxygen isotope reactions to be probed at energies that correspond to stellar plasma temperatures. For stars with masses between 0.8 M_⊙ < M < 8.0 M_⊙, nucleosynthesis enters its final phase during the asymptotic giant branch (AGB) stage. This is an evolutionary period characterized by grain condensation that occurs in the stellar atmosphere; the star also experiences significant mass loss during this period of instability. Presolar grain production can often be attributed to this unique stellar environment. A subset of presolar oxide grains features dramatic ¹⁸O depletion that can not be explained by the standard asymptotic giant star burning stages and dredge-up models. An extra mixing process for low-mass asymptotic giant branch stars, known as cool bottom processing (CBP), was used in the literature to explain this and other anomalies. Cool bottom processing can also occur during the red giant branch (RGB) phase, but it is not thought to contribute to the extreme ¹⁸O depletion observed within certain stellar environments and within presolar grain samples. However, intense depletion could result from the ¹⁸O + p processes during cool bottom processing in low-mass AGB stars. A portion of this dissertation describes a study of the ¹⁸O(p,γ)¹⁹F reaction at low energies performed at LENA. Based on these new results, it was found that the resonance at E_R = 95 keV has a negligible effect on the reaction rate at the temperatures associated with cool bottom processing when compared to the (p,α) reaction. It was also observed that the direct capture S-factor is almost a factor of 2 lower than the previously recommended value at low energies. The product of this research is a new thermonuclear reaction rate for… Advisors/Committee Members: Buckner, Matthew, Iliadis, Christian, Cecil, Gerald, Champagne, Arthur, Clegg, Thomas, Heitsch, Fabian.

Subjects/Keywords: Nuclear physics; Astronomy; College of Arts and Sciences; Department of Physics and Astronomy

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APA (6^th Edition):

Buckner, M. (2014). Hydrogen Burning of the Rare Oxygen Isotopes. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:876509f7-86a6-4773-a854-00420c972e7a

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Buckner, Matthew. “Hydrogen Burning of the Rare Oxygen Isotopes.” 2014. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:876509f7-86a6-4773-a854-00420c972e7a.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Buckner, Matthew. “Hydrogen Burning of the Rare Oxygen Isotopes.” 2014. Web. 23 Jan 2021.

Vancouver:

Buckner M. Hydrogen Burning of the Rare Oxygen Isotopes. [Internet] [Thesis]. University of North Carolina; 2014. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:876509f7-86a6-4773-a854-00420c972e7a.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Buckner M. Hydrogen Burning of the Rare Oxygen Isotopes. [Thesis]. University of North Carolina; 2014. Available from: https://cdr.lib.unc.edu/record/uuid:876509f7-86a6-4773-a854-00420c972e7a

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

9. Beicker, Kellie. Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research.

Degree: Physics and Astronomy, 2016, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:30c8dfa8-7037-4dce-8023-aaacda3feb72

► Key metrics for understanding cell response to mechanical stimuli include rearrangement of the cytoskeletal and nucleoskeletal structure, induced strains and biochemical distributions; however, structural information… (more)

▼ Key metrics for understanding cell response to mechanical stimuli include rearrangement of the cytoskeletal and nucleoskeletal structure, induced strains and biochemical distributions; however, structural information during applied stress is limited by our ability to image cells under load. In order to study the mechanics of single cells and subcellular components under load, I have developed a unique imaging system that combines an atomic force microscope (AFM) with both vertical light-sheet (VLS) illumination and a new imaging technique called PRISM – Pathway Rotated Imaging for Sideways Microscopy. The combined AFM and PRISM system facilitates the imaging of cell deformation in the direction of applied force with accompanying pico-Newton resolution force measurements. The additional inclusion of light-sheet microscopy improves the signal-to-noise ratio achieved by illumination of only a thin layer of the cell. This system is capable of pico-newton resolution force measurements with simultaneous side-view high frame rate imaging for single-molecule and single-cell force studies. Longer-term goals for this instrument are to investigate how external mechanical stimuli, specifically single-molecule interactions, alter gene expression, motility, and differentiation. The overall goal of my dissertation work is to design a tool useful for mechanobiology studies of single cells. This requires the design and implementation of PRISM and VLS systems that can be coupled to the standard Asylum AFM on inverted optical microscope. I also examine the strategy and implementation of experimental procedures and data analysis pipelines for single-cell and single-molecule force spectroscopy. These goals can be broken down as follows: • Performed single-molecule force spectroscopy experiments. • Performed single-cell force spectroscopy experiments. • Constructed and characterized the side-view microscopy system. • Applied combined AFM and side-vew microscopy system. Advisors/Committee Members: Beicker, Kellie, Superfine, Richard, Falvo, Michael, Cheney, Richard, Mitran, Sorin, Cecil, Gerald.

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Beicker, K. (2016). Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:30c8dfa8-7037-4dce-8023-aaacda3feb72

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Beicker, Kellie. “Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research.” 2016. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:30c8dfa8-7037-4dce-8023-aaacda3feb72.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Beicker, Kellie. “Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research.” 2016. Web. 23 Jan 2021.

Vancouver:

Beicker K. Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research. [Internet] [Thesis]. University of North Carolina; 2016. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:30c8dfa8-7037-4dce-8023-aaacda3feb72.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Beicker K. Development of a Combined Atomic Force Microscopy and Side-View Imaging System for Mechanotransduction Research. [Thesis]. University of North Carolina; 2016. Available from: https://cdr.lib.unc.edu/record/uuid:30c8dfa8-7037-4dce-8023-aaacda3feb72

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

10. Wierman, Kevin. Studies of Charge Accumulation In The KATRIN Main Spectrometer.

Degree: Physics and Astronomy, 2016, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:a62e30ba-d8cb-4e6d-9fcb-84166c328b99

► Experiments in recent years have shown neutrinos have non-zero rest mass. The Karlsruhe Tritium Neutrino experiment (KATRIN) will directly probe the electron anti-neutrino mass using… (more)

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wierman, K. (2016). Studies of Charge Accumulation In The KATRIN Main Spectrometer. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:a62e30ba-d8cb-4e6d-9fcb-84166c328b99

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wierman, Kevin. “Studies of Charge Accumulation In The KATRIN Main Spectrometer.” 2016. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:a62e30ba-d8cb-4e6d-9fcb-84166c328b99.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wierman, Kevin. “Studies of Charge Accumulation In The KATRIN Main Spectrometer.” 2016. Web. 23 Jan 2021.

Vancouver:

Wierman K. Studies of Charge Accumulation In The KATRIN Main Spectrometer. [Internet] [Thesis]. University of North Carolina; 2016. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:a62e30ba-d8cb-4e6d-9fcb-84166c328b99.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wierman K. Studies of Charge Accumulation In The KATRIN Main Spectrometer. [Thesis]. University of North Carolina; 2016. Available from: https://cdr.lib.unc.edu/record/uuid:a62e30ba-d8cb-4e6d-9fcb-84166c328b99

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of North Carolina

11. Wierman, Kevin. Studies of Charge Accumulation In The KATRIN Main Spectrometer.

Degree: Physics and Astronomy, 2016, University of North Carolina

URL: https://cdr.lib.unc.edu/record/uuid:116cdd53-957b-4b40-bd8f-0203556ee1b4

► Experiments in recent years have shown neutrinos have non-zero rest mass. The Karlsruhe Tritium Neutrino experiment (KATRIN) will directly probe the electron anti-neutrino mass using… (more)

Subjects/Keywords: College of Arts and Sciences; Department of Physics and Astronomy

Record Details Similar Records Cite « Share

❌

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Wierman, K. (2016). Studies of Charge Accumulation In The KATRIN Main Spectrometer. (Thesis). University of North Carolina. Retrieved from https://cdr.lib.unc.edu/record/uuid:116cdd53-957b-4b40-bd8f-0203556ee1b4

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16^th Edition):

Wierman, Kevin. “Studies of Charge Accumulation In The KATRIN Main Spectrometer.” 2016. Thesis, University of North Carolina. Accessed January 23, 2021. https://cdr.lib.unc.edu/record/uuid:116cdd53-957b-4b40-bd8f-0203556ee1b4.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7^th Edition):

Wierman, Kevin. “Studies of Charge Accumulation In The KATRIN Main Spectrometer.” 2016. Web. 23 Jan 2021.

Vancouver:

Wierman K. Studies of Charge Accumulation In The KATRIN Main Spectrometer. [Internet] [Thesis]. University of North Carolina; 2016. [cited 2021 Jan 23]. Available from: https://cdr.lib.unc.edu/record/uuid:116cdd53-957b-4b40-bd8f-0203556ee1b4.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Wierman K. Studies of Charge Accumulation In The KATRIN Main Spectrometer. [Thesis]. University of North Carolina; 2016. Available from: https://cdr.lib.unc.edu/record/uuid:116cdd53-957b-4b40-bd8f-0203556ee1b4

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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Open Access Theses and Dissertations