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You searched for +publisher:"University of Minnesota" +contributor:("Jaime Modiano, V.M.D, Ph.D"). One record found.

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University of Minnesota

1. Zamora, Edward Anthony. Dual labeling of syngeneic tumor cells for in vivo and in vitro localization.

Degree: MS, Microbiology, immunology and cancer biology, 2012, University of Minnesota

University of Minnesota M.S. thesis. August 2012. Major: Microbiology, immunology and cancer biology. Advisor: Jaime Modiano, V.M.D, Ph.D. 1 computer file (PDF); v, 40 pages.

Animal models in cancer research have been critical to much of our understanding of tumor biology. However, while early models have advanced the field, improvements need to be made if we are to realize the ultimate goal of translational relevance. In this research, we sought to address the difficulties of in vivo and in vitro tumor cell tracking and localization by using two established models, B16 melanoma and Lewis lung carcinoma. To this end, cells were stably transfected with a dual reporter vector containing green fluorescent protein (GFP) and firefly luciferase (fLuc) genes and clonal isolates were compared with parental lines. In at least one instance, the monoclonal tumor model, LLC_GL:HI2 was shown to retain tumorigenic potential while also retaining expression of the reporter genes in vivo and in vitro.

Advisors/Committee Members: Jaime Modiano, V.M.D, Ph.D.

Subjects/Keywords: Cancer; Oncology

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Zamora, E. A. (2012). Dual labeling of syngeneic tumor cells for in vivo and in vitro localization. (Masters Thesis). University of Minnesota. Retrieved from http://purl.umn.edu/140180

Chicago Manual of Style (16th Edition):

Zamora, Edward Anthony. “Dual labeling of syngeneic tumor cells for in vivo and in vitro localization.” 2012. Masters Thesis, University of Minnesota. Accessed July 16, 2019. http://purl.umn.edu/140180.

MLA Handbook (7th Edition):

Zamora, Edward Anthony. “Dual labeling of syngeneic tumor cells for in vivo and in vitro localization.” 2012. Web. 16 Jul 2019.

Vancouver:

Zamora EA. Dual labeling of syngeneic tumor cells for in vivo and in vitro localization. [Internet] [Masters thesis]. University of Minnesota; 2012. [cited 2019 Jul 16]. Available from: http://purl.umn.edu/140180.

Council of Science Editors:

Zamora EA. Dual labeling of syngeneic tumor cells for in vivo and in vitro localization. [Masters Thesis]. University of Minnesota; 2012. Available from: http://purl.umn.edu/140180

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