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You searched for +publisher:"University of Michigan" +contributor:("Smith, Janet L"). Showing records 1 – 18 of 18 total matches.

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University of Michigan

1. Lopez, Jeffrey. Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases.

Degree: PhD, Chemical Biology, 2017, University of Michigan

 Lysine acetylation is a dynamic post-translational modification occurring ubiquitously in cells. The histone deacetylase (HDAC) family catalyzes the removal of an acetyl group from the… (more)

Subjects/Keywords: Histone deacetylase 8; protein substrates; Chemical Biology; Acetylation; Biological Chemistry; Science

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APA (6th Edition):

Lopez, J. (2017). Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/138676

Chicago Manual of Style (16th Edition):

Lopez, Jeffrey. “Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/138676.

MLA Handbook (7th Edition):

Lopez, Jeffrey. “Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases.” 2017. Web. 24 Jun 2019.

Vancouver:

Lopez J. Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/138676.

Council of Science Editors:

Lopez J. Understanding HDAC8-Catalyzed Deacetylation: From New Substrates to Diseases. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/138676


University of Michigan

2. Maloney, Finn. Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching.

Degree: PhD, Chemical Biology, 2017, University of Michigan

 Modular polyketide synthase (PKS) pathways generate a diverse array of pharmaceutically significant small molecule natural products, and synthetic PKS biology may facilitate pharmaceutical development, production… (more)

Subjects/Keywords: Natural Products; Curacin; Polyketide Synthase; Structural Biology; HMG Synthase; Acyl Carrier Protein; Biological Chemistry; Science

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APA (6th Edition):

Maloney, F. (2017). Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140829

Chicago Manual of Style (16th Edition):

Maloney, Finn. “Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140829.

MLA Handbook (7th Edition):

Maloney, Finn. “Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching.” 2017. Web. 24 Jun 2019.

Vancouver:

Maloney F. Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140829.

Council of Science Editors:

Maloney F. Structure, Biochemistry, and Substrate Selectivity of the Hydroxymethylglutaryl Synthase of Polyketide -Branching. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140829


University of Michigan

3. Li, Shasha. Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery.

Degree: PhD, Medicinal Chemistry, 2017, University of Michigan

 Biosynthetic exploration of natural products provides a promising opportunity to produce novel bioactive molecules for drug development. Hapalindole-type alkaloids are a large group of secondary… (more)

Subjects/Keywords: biosynthetic pathway; hapalindole-type alkaloids; cyanobacteria; natural products; Cope rearrangement; drug discovery; Biological Chemistry; Chemistry; Genetics; Natural Resources and Environment; Science (General); Science

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APA (6th Edition):

Li, S. (2017). Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140902

Chicago Manual of Style (16th Edition):

Li, Shasha. “Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140902.

MLA Handbook (7th Edition):

Li, Shasha. “Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery.” 2017. Web. 24 Jun 2019.

Vancouver:

Li S. Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140902.

Council of Science Editors:

Li S. Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140902


University of Michigan

4. Gates, Stephanie. Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM.

Degree: PhD, Chemical Biology, 2017, University of Michigan

 Chaperone proteins are central to protein quality control and cell signaling. Three major classes of chaperones include foldases, holdases and disaggregases. Foldases aid proteins in… (more)

Subjects/Keywords: Cryo-EM of Chaperone Proteins; Biological Chemistry; Science

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APA (6th Edition):

Gates, S. (2017). Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140911

Chicago Manual of Style (16th Edition):

Gates, Stephanie. “Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140911.

MLA Handbook (7th Edition):

Gates, Stephanie. “Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM.” 2017. Web. 24 Jun 2019.

Vancouver:

Gates S. Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140911.

Council of Science Editors:

Gates S. Understanding Protein Folding Mechanisms of Chaperone Proteins Using Cryo-EM. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140911


University of Michigan

5. Scharf, Nathan. Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay.

Degree: PhD, Medicinal Chemistry, 2017, University of Michigan

 Tuberculosis (TB) is a global health problem caused by Mycobacterium tuberculosis with 8-10 million new cases each year according to the World Health Organization. The… (more)

Subjects/Keywords: RNA polymerase; transcription; drug discovery; rifampin; high-throughput screen; tuberculosis; Biological Chemistry; Science

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APA (6th Edition):

Scharf, N. (2017). Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140941

Chicago Manual of Style (16th Edition):

Scharf, Nathan. “Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140941.

MLA Handbook (7th Edition):

Scharf, Nathan. “Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay.” 2017. Web. 24 Jun 2019.

Vancouver:

Scharf N. Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140941.

Council of Science Editors:

Scharf N. Identification and Evaluation of Bacterial RNA Polymerase Inhibitors Using a Novel Plasmid-based Transcription Assay. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140941


University of Michigan

6. Rush, Katherine. Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis.

Degree: PhD, Chemical Biology, 2018, University of Michigan

 Methylmercury biosynthesis is a biologically-mediated process linked to expression of the recently discovered hgcAB gene products. The environmental conversion of toxic Hg(II) to MeHg, which… (more)

Subjects/Keywords: methylmercury; biogeochemistry; mercury binding protein; environmental toxic element cycles; iron-sulfur protein; cobalamin (vitamin B12); Biological Chemistry; Science

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APA (6th Edition):

Rush, K. (2018). Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/147540

Chicago Manual of Style (16th Edition):

Rush, Katherine. “Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis.” 2018. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/147540.

MLA Handbook (7th Edition):

Rush, Katherine. “Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis.” 2018. Web. 24 Jun 2019.

Vancouver:

Rush K. Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/147540.

Council of Science Editors:

Rush K. Expression and Characterization of HgcA and HgcB, Two Proteins Involved in Methylmercury Biosynthesis. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/147540


University of Michigan

7. Koch, Aaron. Investigations into the Stucture and Function of Type I Polyketide Synthases.

Degree: PhD, Cancer Biology, 2017, University of Michigan

 The polyketide (PK) class of natural products constitutes an abundant array of secondary metabolites produced in microorganisms, many of which possess potential medicinal value, especially… (more)

Subjects/Keywords: natural products biosynthesis; Biological Chemistry; Science

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APA (6th Edition):

Koch, A. (2017). Investigations into the Stucture and Function of Type I Polyketide Synthases. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140831

Chicago Manual of Style (16th Edition):

Koch, Aaron. “Investigations into the Stucture and Function of Type I Polyketide Synthases.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140831.

MLA Handbook (7th Edition):

Koch, Aaron. “Investigations into the Stucture and Function of Type I Polyketide Synthases.” 2017. Web. 24 Jun 2019.

Vancouver:

Koch A. Investigations into the Stucture and Function of Type I Polyketide Synthases. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140831.

Council of Science Editors:

Koch A. Investigations into the Stucture and Function of Type I Polyketide Synthases. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140831


University of Michigan

8. Slocum, Samuel. Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture.

Degree: PhD, Biological Chemistry, 2017, University of Michigan

 Natural products are bioactive molecules produced across the tree of life and have been used medicinally by humans for millennia. Isolation and characterization of these… (more)

Subjects/Keywords: Natural Products Biosynthesis; Bryostatin; Polyketide Synthase; Biological Chemistry; Health Sciences

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APA (6th Edition):

Slocum, S. (2017). Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140872

Chicago Manual of Style (16th Edition):

Slocum, Samuel. “Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140872.

MLA Handbook (7th Edition):

Slocum, Samuel. “Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture.” 2017. Web. 24 Jun 2019.

Vancouver:

Slocum S. Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140872.

Council of Science Editors:

Slocum S. Biochemical Studies of Polyketide Beta-Branching and Polyketide Synthase Module Architecture. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140872


University of Michigan

9. Cruz, Osvaldo. The PH Domain as a Mediator of G?? Effector Interactions.

Degree: PhD, Chemical Biology, 2017, University of Michigan

 G protein βγ subunits regulate the activity, via direct interaction, of a large number of downstream effectors in GPCR signaling pathways. Whereas much is known… (more)

Subjects/Keywords: Regulation of phospholipase C beta; G protein-coupled receptor kinase; Biological Chemistry; Science

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APA (6th Edition):

Cruz, O. (2017). The PH Domain as a Mediator of G?? Effector Interactions. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140945

Chicago Manual of Style (16th Edition):

Cruz, Osvaldo. “The PH Domain as a Mediator of G?? Effector Interactions.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140945.

MLA Handbook (7th Edition):

Cruz, Osvaldo. “The PH Domain as a Mediator of G?? Effector Interactions.” 2017. Web. 24 Jun 2019.

Vancouver:

Cruz O. The PH Domain as a Mediator of G?? Effector Interactions. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140945.

Council of Science Editors:

Cruz O. The PH Domain as a Mediator of G?? Effector Interactions. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140945


University of Michigan

10. DeMars II, Matthew. Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics.

Degree: PhD, Chemical Biology, 2017, University of Michigan

 Selective functionalization of chemically inert carbon-hydrogen (C–H) bonds embodies one of the grand challenges of organic chemistry and provides a key focus of research in… (more)

Subjects/Keywords: Cytochrome P450; Macrolide antibiotics; Natural products; Biosynthesis; Biological Chemistry; Chemistry; Science

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APA (6th Edition):

DeMars II, M. (2017). Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/140964

Chicago Manual of Style (16th Edition):

DeMars II, Matthew. “Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/140964.

MLA Handbook (7th Edition):

DeMars II, Matthew. “Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics.” 2017. Web. 24 Jun 2019.

Vancouver:

DeMars II M. Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/140964.

Council of Science Editors:

DeMars II M. Structure and Biochemistry of Cytochromes P450 Involved in the Biosynthesis of Macrolide Antibiotics. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/140964


University of Michigan

11. Dan, Qingyun. Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis.

Degree: PhD, Biological Chemistry, 2017, University of Michigan

 Prenylated indole alkaloids are a class of natural products with great structural diversity and pharmaceutical potential. These alkaloids, which are isolated from various fungi, mostly… (more)

Subjects/Keywords: prenylated indole alkaloids; bicyclo[2.2.2]diazaoctane; intramolecular Diels-Alder reaction; malbrancheamide biosynthesis; Biological Chemistry; Science

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APA (6th Edition):

Dan, Q. (2017). Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/137149

Chicago Manual of Style (16th Edition):

Dan, Qingyun. “Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/137149.

MLA Handbook (7th Edition):

Dan, Qingyun. “Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis.” 2017. Web. 24 Jun 2019.

Vancouver:

Dan Q. Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/137149.

Council of Science Editors:

Dan Q. Structural and Biochemical Characterization of the Early Steps in Fungal Indole Alkaloid Biosynthesis. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/137149


University of Michigan

12. Sikkema, Andrew. Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways.

Degree: PhD, Biological Chemistry, 2017, University of Michigan

 Natural products are a rich source of diverse chemical compounds, many with pharmaceutical potential. Structural and biochemical investigations into the initiation steps of three natural… (more)

Subjects/Keywords: Natural Products; Olefin Synthase; Apratoxin; Cahuitamycin; Initiation of Natural Product Biosynthesis; 1-nonadecene; Biological Chemistry; Science

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APA (6th Edition):

Sikkema, A. (2017). Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/137167

Chicago Manual of Style (16th Edition):

Sikkema, Andrew. “Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/137167.

MLA Handbook (7th Edition):

Sikkema, Andrew. “Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways.” 2017. Web. 24 Jun 2019.

Vancouver:

Sikkema A. Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/137167.

Council of Science Editors:

Sikkema A. Structural and Biochemical Studies of the Initiation Steps in Three Natural Product Biosynthetic Pathways. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/137167


University of Michigan

13. Clark, Jordan. Structural Investigation of Binding Events in Proteins.

Degree: PhD, Medicinal Chemistry, 2018, University of Michigan

 Understanding the biophysical properties that describe protein binding events has allowed for the advancement of drug discovery through structure-based drug design and in silico methodology.… (more)

Subjects/Keywords: Protein flexibility; Protein structure database; Protein-ligand binding; Protein-protein interaction (PPI); Biological Chemistry; Science

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APA (6th Edition):

Clark, J. (2018). Structural Investigation of Binding Events in Proteins. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/145943

Chicago Manual of Style (16th Edition):

Clark, Jordan. “Structural Investigation of Binding Events in Proteins.” 2018. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/145943.

MLA Handbook (7th Edition):

Clark, Jordan. “Structural Investigation of Binding Events in Proteins.” 2018. Web. 24 Jun 2019.

Vancouver:

Clark J. Structural Investigation of Binding Events in Proteins. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/145943.

Council of Science Editors:

Clark J. Structural Investigation of Binding Events in Proteins. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/145943


University of Michigan

14. Dodge, Gregory. Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase.

Degree: PhD, Biological Chemistry, 2018, University of Michigan

 Polyketides are chemically diverse bioactive natural products that often harbor desirable therapeutic characteristics. As such, the biological machinery used to synthesize these compounds are valuable… (more)

Subjects/Keywords: polyketide synthase; dehydratase; fatty acid synthase; structural biology; Biological Chemistry; Science

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APA (6th Edition):

Dodge, G. (2018). Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/146121

Chicago Manual of Style (16th Edition):

Dodge, Gregory. “Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase.” 2018. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/146121.

MLA Handbook (7th Edition):

Dodge, Gregory. “Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase.” 2018. Web. 24 Jun 2019.

Vancouver:

Dodge G. Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/146121.

Council of Science Editors:

Dodge G. Structural and Biochemical Studies of Polyketide Synthase and Fatty Acid Synthase Dehydratase. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/146121


University of Michigan

15. Skiba, Meredith. Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis.

Degree: PhD, Biological Chemistry, 2018, University of Michigan

 Polyketide natural products are a chemically diverse class of small molecules possessing a variety of therapeutic applications. Modular type I polyketide synthases (PKS) use a… (more)

Subjects/Keywords: Natural Product Biosynthesis; Polyketide; Methyltransferase; Biological Chemistry; Science

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APA (6th Edition):

Skiba, M. (2018). Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/147563

Chicago Manual of Style (16th Edition):

Skiba, Meredith. “Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis.” 2018. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/147563.

MLA Handbook (7th Edition):

Skiba, Meredith. “Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis.” 2018. Web. 24 Jun 2019.

Vancouver:

Skiba M. Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/147563.

Council of Science Editors:

Skiba M. Structural and Biochemical Investigation of Methylation and Elucidation of t-Butyl Formation in Polyketide Biosynthesis. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/147563


University of Michigan

16. Jepsen, Lauren. Nucleotide and Polymerization Effects on Actin Structure and Dynamics.

Degree: PhD, Bioinformatics, 2018, University of Michigan

 Actin is one of the most highly conserved and abundant proteins found in eukaryotic cells, essential for determining cell shape, polarity and motility, as well… (more)

Subjects/Keywords: Actin; Molecular Dynamics; DFNA20/26; Polymerization; Health Sciences; Science

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APA (6th Edition):

Jepsen, L. (2018). Nucleotide and Polymerization Effects on Actin Structure and Dynamics. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/147698

Chicago Manual of Style (16th Edition):

Jepsen, Lauren. “Nucleotide and Polymerization Effects on Actin Structure and Dynamics.” 2018. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/147698.

MLA Handbook (7th Edition):

Jepsen, Lauren. “Nucleotide and Polymerization Effects on Actin Structure and Dynamics.” 2018. Web. 24 Jun 2019.

Vancouver:

Jepsen L. Nucleotide and Polymerization Effects on Actin Structure and Dynamics. [Internet] [Doctoral dissertation]. University of Michigan; 2018. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/147698.

Council of Science Editors:

Jepsen L. Nucleotide and Polymerization Effects on Actin Structure and Dynamics. [Doctoral Dissertation]. University of Michigan; 2018. Available from: http://hdl.handle.net/2027.42/147698


University of Michigan

17. Dunyak, Bryan. Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics.

Degree: PhD, Biological Chemistry, 2016, University of Michigan

 Peptidyl-prolyl isomerases (PPIases) are a ubiquitously expressed super family of proteins that catalyze the cis/trans isomerization of prolyl bonds. Proline conformation acts as a regulatory… (more)

Subjects/Keywords: Natural-product inspired therapeutics; Peptidyl-prolyl isomerases (PPIases) as promising drug targets; Enhanced pharmacological properties of bifunctional molecules; Semisynthetic modification of macrolide immunosuppressants; Biological Chemistry; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Dunyak, B. (2016). Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/135789

Chicago Manual of Style (16th Edition):

Dunyak, Bryan. “Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics.” 2016. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/135789.

MLA Handbook (7th Edition):

Dunyak, Bryan. “Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics.” 2016. Web. 24 Jun 2019.

Vancouver:

Dunyak B. Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/135789.

Council of Science Editors:

Dunyak B. Peptidyl-Prolyl Isomerases as Promising Targets for Natural Product-Inspired Therapeutics. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/135789

18. Motl, Nicole. Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese.

Degree: PhD, Biological Chemistry, 2017, University of Michigan

 Hydrogen sulfide (H2S) is the third eukaryotic gaseous signaling molecule and evokes a broad range of physiological effects. H2S levels are governed by the rates… (more)

Subjects/Keywords: Hydrogen Sulfide Metabolism; Biological Chemistry; Science

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Motl, N. (2017). Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/138577

Chicago Manual of Style (16th Edition):

Motl, Nicole. “Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese.” 2017. Doctoral Dissertation, University of Michigan. Accessed June 24, 2019. http://hdl.handle.net/2027.42/138577.

MLA Handbook (7th Edition):

Motl, Nicole. “Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese.” 2017. Web. 24 Jun 2019.

Vancouver:

Motl N. Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese. [Internet] [Doctoral dissertation]. University of Michigan; 2017. [cited 2019 Jun 24]. Available from: http://hdl.handle.net/2027.42/138577.

Council of Science Editors:

Motl N. Structural Enzymology of Sulfide Oxidation by Persulfide Dioxygenase and Rhodanese. [Doctoral Dissertation]. University of Michigan; 2017. Available from: http://hdl.handle.net/2027.42/138577

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