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You searched for +publisher:"University of Michigan" +contributor:("Mc Innis, Melvin G"). Showing records 1 – 2 of 2 total matches.

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University of Michigan

1. O'Donnell, Lisa Anne. An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder.

Degree: PhD, Social Work and Psychology, 2016, University of Michigan

The goal of this research was to identify predictors of poor occupational functioning (OF) in individuals with bipolar disorder (BD). This investigation involved three distinct, but related studies. The first study investigated the effects of clinical, demographic and neurocognitive features on OF in individuals with BD. Previous work found that as depression and neurocognitive deficits increased, OF decreased. However, few studies have examined these features over time using distinct aspects of work functioning. This study employed multilevel modeling (MLM) to determine which demographic, clinical and neurocognitive characteristics influence 4 aspects of work functioning over 5 years: attendance, conflict, enjoyment, performance. Those with higher levels of depression were more likely to experience difficulties in all work domains that persisted over the entire 5 years. The second study investigated the influence of interpersonal features of individuals with BD on OF. Prior work has typically investigated traditional features of BD (e.g., clinical, neurocognitive) overlooking interpersonal characteristics. This study employed MLM to determine which demographic, clinical and interpersonal characteristics (i.e., personality, impulsivity, hostility, social anxiety) of individuals with BD affect work functioning across 5 years. Those with higher levels of depression were more likely to experience impairments related to work attendance, conflict with coworkers and supervisors, quality of work and enjoyment from work. At baseline, higher levels of mania were associated with improved attendance at work. Yet over time, mania negatively affected overall work functioning, attendance at work, and work performance. Prior work on OF focuses mainly on the individual’s features of BD neglecting the environment. The third study took a novel approach and evaluated the relationship between social aspects of the work environment and work outcomes among individuals with BD. This study employed regressions in order to determine which demographics, mood symptoms and aspects of the work environment (i.e., conflict, exclusion, social support, stigma) predict work status and work functioning for individuals with BD. Exclusion and stigma at work predicted unemployment, whereas depressive symptoms and conflict at work predicted poorer work functioning. Taken together, this dissertation aims to inform approaches to remediating poor OF ultimately improving the overall functioning of individuals with BD. Advisors/Committee Members: Deldin, Patricia J (committee member), Himle, Joseph Alan (committee member), Mc Innis, Melvin G (committee member), Ryan, Kelly (committee member), Grogan-Kaylor, Andrew C (committee member).

Subjects/Keywords: An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder; Psychology; Social Work; Social Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

O'Donnell, L. A. (2016). An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/120711

Chicago Manual of Style (16th Edition):

O'Donnell, Lisa Anne. “An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder.” 2016. Doctoral Dissertation, University of Michigan. Accessed December 04, 2020. http://hdl.handle.net/2027.42/120711.

MLA Handbook (7th Edition):

O'Donnell, Lisa Anne. “An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder.” 2016. Web. 04 Dec 2020.

Vancouver:

O'Donnell LA. An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder. [Internet] [Doctoral dissertation]. University of Michigan; 2016. [cited 2020 Dec 04]. Available from: http://hdl.handle.net/2027.42/120711.

Council of Science Editors:

O'Donnell LA. An Investigation on Predictors of Occupational Functioning in Individuals with Bipolar Disorder. [Doctoral Dissertation]. University of Michigan; 2016. Available from: http://hdl.handle.net/2027.42/120711


University of Michigan

2. Chun, Jinsoo. Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia.

Degree: PhD, Psychology, 2010, University of Michigan

Response inhibition deficits and the influence of emotion on response inhibition were investigated in patients with schizophrenia (SZ), schizoaffective disorder (SAD) and bipolar I disorder (BD) with event-related brain potentials (ERPs). Further, it was tested whether the neural deficits in response inhibition can differentiate each group by applying discriminant functional analysis. In order to fulfill the study goal, two different versions of Go/NoGo tasks were used: non-affective stimulus (alphabet letters) and the other with affective stimulus (faces with emotions).Two event-related brain potentials (ERPs), N200 and P300 components were measured for non-affective Go/NoGo task, while face-specific ERPs, N170 and N250, in addition to P300, were further obtained for emotional Go/NoGo task . With lateralized non-affective Go/NoGo task, the first study revealed that SZ showed left-lateralized response inhibition deficit over the frontal region measured by P300. SAD showed prolonged stimulus evaluation time in the early stage of response inhibition manifested by N200 latency. The second study replicated SZ’s response inhibition deficit associated with left hemisphere dysfunction. BD disorder did not show deficits in response inhibition compared to that in SZ but delayed overall cognitive stimulus evaluation was observed. When the non-affective stimuli were replaced with faces with four categories of emotions (happy, angry, sad, and neutral), emotion modulation effect (larger ERP amplitudes for faces with emotions than for neutral faces) was observed only in response execution (Go trials) not in response inhibition (NoGo trials) process in both patients and controls. Both SZ and BD showed deficits in early facial structure encoding revealed by reduced amplitude in N170 component but relatively intact in early facial affect decoding compared to healthy controls (CT). In three studies, it was replicated that P300 amplitude and N200 latency successfully discriminated SZ, SAD (study 1), BD (study 2 & 3), and CT, which implicates that distinct ERP patterns in response inhibition task can become endophenotypes of each psychiatric disorder. Advisors/Committee Members: Deldin, Patricia J. (committee member), Gehring, William J. (committee member), Mc Innis, Melvin G. (committee member), Taylor, Stephan F. (committee member).

Subjects/Keywords: Response Inhibition; Schizophrenia; Bipolar I Disorder; Event Related Brain Potentials (ERPs); Psychology; Social Sciences

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Chun, J. (2010). Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia. (Doctoral Dissertation). University of Michigan. Retrieved from http://hdl.handle.net/2027.42/78787

Chicago Manual of Style (16th Edition):

Chun, Jinsoo. “Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia.” 2010. Doctoral Dissertation, University of Michigan. Accessed December 04, 2020. http://hdl.handle.net/2027.42/78787.

MLA Handbook (7th Edition):

Chun, Jinsoo. “Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia.” 2010. Web. 04 Dec 2020.

Vancouver:

Chun J. Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia. [Internet] [Doctoral dissertation]. University of Michigan; 2010. [cited 2020 Dec 04]. Available from: http://hdl.handle.net/2027.42/78787.

Council of Science Editors:

Chun J. Response Inhibition and Emotional Modulation Effect on Response Inhibition in Biopolar I Disorder and Schizophrenia. [Doctoral Dissertation]. University of Michigan; 2010. Available from: http://hdl.handle.net/2027.42/78787

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