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You searched for +publisher:"University of Manitoba" +contributor:("Tipples, Graham (Medical Microbiology)"). One record found.

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University of Manitoba

1. EisBrenner, Tracie. The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada.

Degree: Medical Microbiology, 2014, University of Manitoba

OBJECTIVES: Measles and rubella are nationally notifiable, vaccine-preventable diseases targeted for elimination by the Pan American Health Organization (PAHO). To support national and international elimination efforts, surveillance optimization is important to ensure rapid case detection, document endemic transmission interruption, identify susceptible populations and inform immunization strategies. While current national surveillance captures confirmed-case data, its performance cannot be assessed using PAHO-recommended surveillance indicators as suspect-case investigation data are required for their estimation. In Canada, the investigation of clinically-suspect measles-like illness (MLI) is highly dependent on laboratory evidence, providing an opportunity to use laboratory data to estimate MLI investigation rates. The Measles and Rubella Surveillance (MARS) pilot project was developed to address existing surveillance challenges with the central hypothesis that (I) ‘it is feasible to develop and implement a real‐time, web‐based measles and rubella surveillance system in the Canadian setting’, and the following sub‐hypotheses: (II) ‘implementation of real‐time surveillance in MARS pilot provinces will result in increased timeliness of national measles and rubella surveillance when compared with established confirmed-case surveillance’, and (III) ‘it is possible to use augmented laboratory data to estimate the performance of national measles and rubella surveillance using adapted PAHO indicators’. METHODS: A MARS application was designed to support centralized real-time measles/ rubella investigation reporting and alerting with integration of non-nominal laboratory and epidemiological data, then developed and piloted using the web-based Canadian Network for Public Health Intelligence platform in British Columbia, Alberta and Newfoundland from June/2011-May/2012. Pre- and post-pilot laboratory surveys were conducted to retrospectively assess national surveillance performance in ‘outbreak’ and ‘non-outbreak’ settings during the 2005‐2011 and pilot years using various surveillance indicators and attributes. Measles IgM serology testing was used as a laboratory-based proxy for MLI investigation to support indicator estimation. RESULTS: Real-time, integrated surveillance was successfully implemented in MARS pilot provinces as modeled within the context of established reporting roles, and surveillance indicators and attributes were estimated using augmented laboratory data. MARS surveillance was more timely than confirmed-case surveillance, and real-time MARS reports exceeded all laboratory-related PAHO targets evaluated: 100% met ‘sample collection’ and ‘receipt’ timelines, and 91.7% met ‘result' timelines (Targets:≥80%); 99.8% of all MLI investigations were discarded (Target:≥95%). A national ‘non-outbreak’ baseline rate of 14 MLI investigations/100 000 population was estimated, whereas MARS pilot sites averaged 22 MLI investigations/100 000 population during the pilot year. While ‘non-outbreak’ investigation… Advisors/Committee Members: Tipples, Graham (Medical Microbiology) (supervisor), Embrée, Joanne (Medical Microbiology) Beaudoin, Carole (Community Health Sciences) Rota, Paul (Emory University) (examiningcommittee).

Subjects/Keywords: measles; rubella; microbiology; epidemiology; virus; surveillance; infectious disease; real-time; Congenital Rubella Syndrome; IgM; indicators; incidence

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APA (6th Edition):

EisBrenner, T. (2014). The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada. (Thesis). University of Manitoba. Retrieved from http://hdl.handle.net/1993/23221

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

EisBrenner, Tracie. “The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada.” 2014. Thesis, University of Manitoba. Accessed August 05, 2020. http://hdl.handle.net/1993/23221.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

EisBrenner, Tracie. “The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada.” 2014. Web. 05 Aug 2020.

Vancouver:

EisBrenner T. The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada. [Internet] [Thesis]. University of Manitoba; 2014. [cited 2020 Aug 05]. Available from: http://hdl.handle.net/1993/23221.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

EisBrenner T. The MARS pilot project: implementing real-time measles and rubella surveillance during elimination phase in Canada. [Thesis]. University of Manitoba; 2014. Available from: http://hdl.handle.net/1993/23221

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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