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You searched for +publisher:"University of Illinois – Urbana-Champaign" +contributor:("Hergenrother, Paul J"). Showing records 1 – 30 of 85 total matches.

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University of Illinois – Urbana-Champaign

1. Nakamura, Bradley A. The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria.

Degree: MS, Chemistry, 2015, University of Illinois – Urbana-Champaign

 Antibiotic-resistant bacterial infections pose a real and increasing threat to public health and welfare. As bacteria continue to develop and spread resistance to currently used… (more)

Subjects/Keywords: Chemistry; antibiotics; resistant bacteria; deoxynybomycin

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APA (6th Edition):

Nakamura, B. A. (2015). The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89155

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Nakamura, Bradley A. “The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria.” 2015. Thesis, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/89155.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Nakamura, Bradley A. “The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria.” 2015. Web. 19 Sep 2019.

Vancouver:

Nakamura BA. The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/89155.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Nakamura BA. The development of deoxynybomycins as potent and selective antibiotics against fluoroquinolone resistant bacteria. [Thesis]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89155

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Urbana-Champaign

2. Knowlton, Aaron. Enhancement of Dicer as a personalized anticancer strategy.

Degree: MS, 0318, 2012, University of Illinois – Urbana-Champaign

 Normal miRNA production is essential for regulating protein expression and cellular fate. Misregulation of miRNA production is emerging as a key factor in the development… (more)

Subjects/Keywords: Dicer; transactivating response RNA-binding protein (TRBP); Dicer1; transactivating response RNA-binding protein 2 (tarbp2); micro ribonucleic acid (miRNA); cancer; Hereditary nonpolyposis colorectal cancer (HNPCC); aptamer; Malachite green

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APA (6th Edition):

Knowlton, A. (2012). Enhancement of Dicer as a personalized anticancer strategy. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/34568

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Knowlton, Aaron. “Enhancement of Dicer as a personalized anticancer strategy.” 2012. Thesis, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/34568.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Knowlton, Aaron. “Enhancement of Dicer as a personalized anticancer strategy.” 2012. Web. 19 Sep 2019.

Vancouver:

Knowlton A. Enhancement of Dicer as a personalized anticancer strategy. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2012. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/34568.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Knowlton A. Enhancement of Dicer as a personalized anticancer strategy. [Thesis]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/34568

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Urbana-Champaign

3. Larson, Amy. Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets.

Degree: MS, 0335, 2013, University of Illinois – Urbana-Champaign

 The rise and spread of drug-resistant pathogens has created a critical need for the continued discovery and development of new antibacterial compounds. Bacterial toxin-antitoxin (TA)… (more)

Subjects/Keywords: toxin-antitoxin system; antibacterial

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APA (6th Edition):

Larson, A. (2013). Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Larson, Amy. “Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets.” 2013. Thesis, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/44445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Larson, Amy. “Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets.” 2013. Web. 19 Sep 2019.

Vancouver:

Larson A. Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2013. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/44445.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Larson A. Investigation of the YefM-YoeBSa toxin-antitoxin systems as novel antibacterial targets. [Thesis]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44445

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Urbana-Champaign

4. Francis, Joshua M. Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity.

Degree: MS, Chemistry, 2017, University of Illinois – Urbana-Champaign

 Head and neck squamous cell carcinomas (HNSCC) are a group of anatomically diverse cancers characterized by their resistance to traditional chemotherapy and radiotherapy modalities. Given… (more)

Subjects/Keywords: Deoxynyboquinone; Head and neck cancer; Head and neck squamous cell carcinomas (HNSCC); Feline oral squamous cell carcinoma cell lines (FOSCC); Radiation; Chemical biology; Organic chemistry; Synthesis

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APA (6th Edition):

Francis, J. M. (2017). Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity. (Thesis). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/97751

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Francis, Joshua M. “Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity.” 2017. Thesis, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/97751.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Francis, Joshua M. “Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity.” 2017. Web. 19 Sep 2019.

Vancouver:

Francis JM. Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity. [Internet] [Thesis]. University of Illinois – Urbana-Champaign; 2017. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/97751.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Francis JM. Targeting head and neck squamous cell carcinoma through NQO1-mediated cytotoxicity. [Thesis]. University of Illinois – Urbana-Champaign; 2017. Available from: http://hdl.handle.net/2142/97751

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation


University of Illinois – Urbana-Champaign

5. Calvaresi, Emilia. Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy.

Degree: PhD, 0318, 2015, University of Illinois – Urbana-Champaign

 Exploiting cancer cell metabolism as an anticancer therapeutic strategy has garnered much attention in recent years. As early as the 1920s, German scientist Otto Warburg… (more)

Subjects/Keywords: Warburg effect; cancer biology; biochemistry; lactate dehydrogenase; lactate dehydrogenase (LDH); lactate dehydrogenase A (LDH-A); cancer metabolism; cancer; glucose transporter-1 (GLUT-1); glucose transporter 1 (GLUT1); glucose transporter (GLUT); glycoconjugation; glucose conjugation; anticancer; anticancer agents; metabolism; small molecules; Cellular Thermal Shift Assay (CETSA); Drug Affinity Responsive Target Stability (DARTS)

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APA (6th Edition):

Calvaresi, E. (2015). Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/72952

Chicago Manual of Style (16th Edition):

Calvaresi, Emilia. “Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/72952.

MLA Handbook (7th Edition):

Calvaresi, Emilia. “Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy.” 2015. Web. 19 Sep 2019.

Vancouver:

Calvaresi E. Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/72952.

Council of Science Editors:

Calvaresi E. Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/72952


University of Illinois – Urbana-Champaign

6. Lambrecht, Michael. The chemical and enzymatic synthesis of poly(ADP-ribose).

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

 Poly(ADP-ribose) synthesis and degradation are important cellular processes associated with the DNA damage response and many other pathways. Traditionally, these processes have been challenging to… (more)

Subjects/Keywords: Poly(ADP-ribose); Total Synthesis; Enzymatic Synthesis; Poly(ADP-ribose) Polymerase; Poly ADP ribose polymerase (PARP); Poly(ADP-ribose) Glycohydrolase (PARG); Raptinal

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APA (6th Edition):

Lambrecht, M. (2016). The chemical and enzymatic synthesis of poly(ADP-ribose). (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/92923

Chicago Manual of Style (16th Edition):

Lambrecht, Michael. “The chemical and enzymatic synthesis of poly(ADP-ribose).” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/92923.

MLA Handbook (7th Edition):

Lambrecht, Michael. “The chemical and enzymatic synthesis of poly(ADP-ribose).” 2016. Web. 19 Sep 2019.

Vancouver:

Lambrecht M. The chemical and enzymatic synthesis of poly(ADP-ribose). [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/92923.

Council of Science Editors:

Lambrecht M. The chemical and enzymatic synthesis of poly(ADP-ribose). [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/92923


University of Illinois – Urbana-Champaign

7. Bair, Joseph. The development of deoxynyboquinone as a personalized anticancer compound.

Degree: PhD, 0335, 2012, University of Illinois – Urbana-Champaign

 The major challenge in cancer therapy is to selectively destroy cancer cells in the presence of healthy tissue. One viable strategy relies on targeting the… (more)

Subjects/Keywords: Cancer; personalized medicine; quinone; total synthesis; reactive oxygen species; NQO1

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APA (6th Edition):

Bair, J. (2012). The development of deoxynyboquinone as a personalized anticancer compound. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/32020

Chicago Manual of Style (16th Edition):

Bair, Joseph. “The development of deoxynyboquinone as a personalized anticancer compound.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/32020.

MLA Handbook (7th Edition):

Bair, Joseph. “The development of deoxynyboquinone as a personalized anticancer compound.” 2012. Web. 19 Sep 2019.

Vancouver:

Bair J. The development of deoxynyboquinone as a personalized anticancer compound. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/32020.

Council of Science Editors:

Bair J. The development of deoxynyboquinone as a personalized anticancer compound. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/32020


University of Illinois – Urbana-Champaign

8. Roth, Howard Steven. Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1.

Degree: PhD, Chemistry, 2015, University of Illinois – Urbana-Champaign

 PAC-1 is an ortho-hydroxy-N-acylhydrazone that induces apoptosis by chelation of antiapoptotic labile zinc, relieving zinc-mediated inhibition of procaspase-3. Favorable results from cell culture and in… (more)

Subjects/Keywords: first procaspase activating compound (PAC-1); procaspase-3; zinc

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APA (6th Edition):

Roth, H. S. (2015). Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/88246

Chicago Manual of Style (16th Edition):

Roth, Howard Steven. “Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/88246.

MLA Handbook (7th Edition):

Roth, Howard Steven. “Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1.” 2015. Web. 19 Sep 2019.

Vancouver:

Roth HS. Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/88246.

Council of Science Editors:

Roth HS. Improving the process synthesis, potency, and pharmacokinetics of the anticancer compound PAC-1. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/88246


University of Illinois – Urbana-Champaign

9. Parkinson, Elizabeth Ivy. Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics.

Degree: PhD, Chemistry, 2015, University of Illinois – Urbana-Champaign

 Cancer and antibiotic-resistant bacterial infections are currently two of the major health concerns facing the United States. Novel therapeutics capable of specifically targeting either cancer… (more)

Subjects/Keywords: NAD(P)H:quinone oxidoreductase-1 (NQO1); reduction-oxidation cycling; deoxynyboquinone; anticancer; fluoroquinolones; antibiotic resistance; deoxynybomycin; DNA gyrase

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APA (6th Edition):

Parkinson, E. I. (2015). Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89176

Chicago Manual of Style (16th Edition):

Parkinson, Elizabeth Ivy. “Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/89176.

MLA Handbook (7th Edition):

Parkinson, Elizabeth Ivy. “Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics.” 2015. Web. 19 Sep 2019.

Vancouver:

Parkinson EI. Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/89176.

Council of Science Editors:

Parkinson EI. Deoxynyboquinones as NQO1-targeted anticancer compounds and deoxynybomycins as potent and selective antibiotics. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89176


University of Illinois – Urbana-Champaign

10. Hicklin, Robert W. Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion.

Degree: PhD, Chemistry, 2015, University of Illinois – Urbana-Champaign

 Ring distortion reactions directly alter the core ring systems of small molecules and can lead to striking changes in molecular structure. Strategic application of ring… (more)

Subjects/Keywords: Ring Distortion; Natural Products; Organic Synthesis; Quinine; Abietic Acid; Pleuromutlin; Fenestrane

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APA (6th Edition):

Hicklin, R. W. (2015). Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/89201

Chicago Manual of Style (16th Edition):

Hicklin, Robert W. “Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/89201.

MLA Handbook (7th Edition):

Hicklin, Robert W. “Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion.” 2015. Web. 19 Sep 2019.

Vancouver:

Hicklin RW. Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/89201.

Council of Science Editors:

Hicklin RW. Chemical diversification of the natural products quinine, abietic acid and pleuromutilin by ring distortion. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/89201


University of Illinois – Urbana-Champaign

11. Morrison, Karen. Chemical diversification and anticancer activity of natural products.

Degree: PhD, 0335, 2014, University of Illinois – Urbana-Champaign

 Natural products have historically formed the backbone of modern drug discovery efforts, particularly for cancer and bacterial infections. Despite this privileged status, difficulties associated with… (more)

Subjects/Keywords: Organic Synthesis; Complexity to Diversity; Natural Products; Anticancer

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APA (6th Edition):

Morrison, K. (2014). Chemical diversification and anticancer activity of natural products. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/46894

Chicago Manual of Style (16th Edition):

Morrison, Karen. “Chemical diversification and anticancer activity of natural products.” 2014. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/46894.

MLA Handbook (7th Edition):

Morrison, Karen. “Chemical diversification and anticancer activity of natural products.” 2014. Web. 19 Sep 2019.

Vancouver:

Morrison K. Chemical diversification and anticancer activity of natural products. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2014. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/46894.

Council of Science Editors:

Morrison K. Chemical diversification and anticancer activity of natural products. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/46894


University of Illinois – Urbana-Champaign

12. Williams, Julia. Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets.

Degree: PhD, 0322, 2014, University of Illinois – Urbana-Champaign

 Toxin–antitoxin (TA) systems are unique modules that effect plasmid stabilization via post-segregational killing of the bacterial host. The genes encoding TA systems also exist on… (more)

Subjects/Keywords: Toxin-antitoxin; antibacterial; RelBE; MazEF; Pseudomonas aeruginosa; Acinetobacter baumannii; ribonuclease; enzymatic assay; plasmid; multi-drug resistance

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APA (6th Edition):

Williams, J. (2014). Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/46947

Chicago Manual of Style (16th Edition):

Williams, Julia. “Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets.” 2014. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/46947.

MLA Handbook (7th Edition):

Williams, Julia. “Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets.” 2014. Web. 19 Sep 2019.

Vancouver:

Williams J. Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2014. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/46947.

Council of Science Editors:

Williams J. Suitability of RelBE and MazEF toxin-antitoxin systems as antibacterial targets. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/46947


University of Illinois – Urbana-Champaign

13. Knezevic, Claire. Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds.

Degree: PhD, 0335, 2014, University of Illinois – Urbana-Champaign

 In the quest for novel anticancer small molecules, one of two major complementary strategies, either a target- or phenotype-based approach, is generally utilized. Target-based approaches,… (more)

Subjects/Keywords: anticancer; poly(ADP-ribose) glycohydrolase (PARG); endoplasmic reticulum (ER) stress; lead hopping; phenotypic screen

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APA (6th Edition):

Knezevic, C. (2014). Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/50439

Chicago Manual of Style (16th Edition):

Knezevic, Claire. “Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds.” 2014. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/50439.

MLA Handbook (7th Edition):

Knezevic, Claire. “Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds.” 2014. Web. 19 Sep 2019.

Vancouver:

Knezevic C. Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2014. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/50439.

Council of Science Editors:

Knezevic C. Development of poly(ADP-ribose) glycohydrolase inhibitors and tetracyclic indoles as anticancer compounds. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2014. Available from: http://hdl.handle.net/2142/50439


University of Illinois – Urbana-Champaign

14. Botham, Rachel C. Development of PAC-1 as a privileged agent for combination chemotherapy.

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

 Elucidation of the molecular mechanisms of cancers has enabled the development of molecularly targeted chemotherapeutics capable of exploiting cancer-specific cellular alterations. Small-molecule activation of procaspase-3… (more)

Subjects/Keywords: caspase; cancer

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APA (6th Edition):

Botham, R. C. (2016). Development of PAC-1 as a privileged agent for combination chemotherapy. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/92913

Chicago Manual of Style (16th Edition):

Botham, Rachel C. “Development of PAC-1 as a privileged agent for combination chemotherapy.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/92913.

MLA Handbook (7th Edition):

Botham, Rachel C. “Development of PAC-1 as a privileged agent for combination chemotherapy.” 2016. Web. 19 Sep 2019.

Vancouver:

Botham RC. Development of PAC-1 as a privileged agent for combination chemotherapy. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/92913.

Council of Science Editors:

Botham RC. Development of PAC-1 as a privileged agent for combination chemotherapy. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/92913


University of Illinois – Urbana-Champaign

15. Hoyt, Mirth T. The anticancer mode of action of the quinone natural product cribrostatin 6.

Degree: PhD, 0335, 2010, University of Illinois – Urbana-Champaign

 Cribrostatin 6 is a quinone-containing natural product that induces the death of cancer cell lines in culture, but its mechanism of action and scope of… (more)

Subjects/Keywords: quinone; anticancer; cribrostatin 6; Reactive oxygen species (ROS)

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APA (6th Edition):

Hoyt, M. T. (2010). The anticancer mode of action of the quinone natural product cribrostatin 6. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/15525

Chicago Manual of Style (16th Edition):

Hoyt, Mirth T. “The anticancer mode of action of the quinone natural product cribrostatin 6.” 2010. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/15525.

MLA Handbook (7th Edition):

Hoyt, Mirth T. “The anticancer mode of action of the quinone natural product cribrostatin 6.” 2010. Web. 19 Sep 2019.

Vancouver:

Hoyt MT. The anticancer mode of action of the quinone natural product cribrostatin 6. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2010. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/15525.

Council of Science Editors:

Hoyt MT. The anticancer mode of action of the quinone natural product cribrostatin 6. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2010. Available from: http://hdl.handle.net/2142/15525


University of Illinois – Urbana-Champaign

16. Palchaudhuri, Rahul. Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics.

Degree: PhD, 0335, 2011, University of Illinois – Urbana-Champaign

 The discovery and development of novel small molecules as anti-cancer agents plays an integral role in the fight against cancer. Such efforts will lead to… (more)

Subjects/Keywords: Cancer; Therapeutic; Mechanism of action; Small Molecule

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APA (6th Edition):

Palchaudhuri, R. (2011). Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/26382

Chicago Manual of Style (16th Edition):

Palchaudhuri, Rahul. “Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics.” 2011. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/26382.

MLA Handbook (7th Edition):

Palchaudhuri, Rahul. “Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics.” 2011. Web. 19 Sep 2019.

Vancouver:

Palchaudhuri R. Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2011. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/26382.

Council of Science Editors:

Palchaudhuri R. Development and Mechanistic Characterization of Novel Small Molecules as Cancer Therapeutics. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2011. Available from: http://hdl.handle.net/2142/26382


University of Illinois – Urbana-Champaign

17. Heeres, James T. High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor.

Degree: PhD, 0318, 2010, University of Illinois – Urbana-Champaign

 High-throughput screening (HTS) has played an integral role in the discovery of lead molecules that eventually are transformed into the therapies of tomorrow. Contributing towards… (more)

Subjects/Keywords: Photonic Crystals; Apoptosis Inducing Factor; apoptosis inducing factor (AIF); Protein-DNA Interactions; Protein-Protein Interactions

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APA (6th Edition):

Heeres, J. T. (2010). High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/17028

Chicago Manual of Style (16th Edition):

Heeres, James T. “High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor.” 2010. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/17028.

MLA Handbook (7th Edition):

Heeres, James T. “High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor.” 2010. Web. 19 Sep 2019.

Vancouver:

Heeres JT. High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2010. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/17028.

Council of Science Editors:

Heeres JT. High-throughput detection of protein???protein and protein???DNA interactions via photonic crystal biosensors: applications to apoptosis inducing factor. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2010. Available from: http://hdl.handle.net/2142/17028


University of Illinois – Urbana-Champaign

18. Moritz, Elizabeth M. The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets.

Degree: PhD, 0322, 2010, University of Illinois – Urbana-Champaign

 Large, low copy number plasmids, such as those harboring antibiotic resistance genes, often possess plasmid maintenance systems to ensure their persistence and inheritance in a… (more)

Subjects/Keywords: toxin-antitoxin; Axe-Txe; Vancomycin-resistant enterococci (VRE); Methicillin-resistant Staphylococcus aureus (MRSA); relBE

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APA (6th Edition):

Moritz, E. M. (2010). The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/17030

Chicago Manual of Style (16th Edition):

Moritz, Elizabeth M. “The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets.” 2010. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/17030.

MLA Handbook (7th Edition):

Moritz, Elizabeth M. “The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets.” 2010. Web. 19 Sep 2019.

Vancouver:

Moritz EM. The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2010. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/17030.

Council of Science Editors:

Moritz EM. The prevalence of toxin-antitoxin systems and their tractability as novel antimicrobial targets. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2010. Available from: http://hdl.handle.net/2142/17030


University of Illinois – Urbana-Champaign

19. Wu, Cong. Development and application of OmpT-based middle down proteomics.

Degree: PhD, 0318, 2013, University of Illinois – Urbana-Champaign

 Information at the protein level is essential to understand the functioning of a biological system. The goal of proteomics is to provide such information as… (more)

Subjects/Keywords: Mass spectrometry; proteomics; Outer membrane protease T (OmpT); restricted proteolysis; middle-down proteomics; mouse brain proteome comparison; yeast histone

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APA (6th Edition):

Wu, C. (2013). Development and application of OmpT-based middle down proteomics. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44772

Chicago Manual of Style (16th Edition):

Wu, Cong. “Development and application of OmpT-based middle down proteomics.” 2013. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/44772.

MLA Handbook (7th Edition):

Wu, Cong. “Development and application of OmpT-based middle down proteomics.” 2013. Web. 19 Sep 2019.

Vancouver:

Wu C. Development and application of OmpT-based middle down proteomics. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2013. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/44772.

Council of Science Editors:

Wu C. Development and application of OmpT-based middle down proteomics. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44772


University of Illinois – Urbana-Champaign

20. Flood, Timothy. Advances in high-throughput screening: better compounds, novel targets, enhanced sensors.

Degree: PhD, 0335, 2013, University of Illinois – Urbana-Champaign

 High throughput screening (HTS) is the dominant force in modern drug discovery. Through the evaluation of large structure collections, novel drug leads can be rapidly… (more)

Subjects/Keywords: high-throughput screening (HTS); drug discovery; natural products; chemical diversity; screening collections; chemoinformatics; cheminformatics; Tanimoto similarity; molecular properties; RNA; RNA binding; myotonic dystrophy; type 1 myotonic dystrophy (DM1); MBNL1; biomolecular interactions; biosensors; protein-ligand interactions; estrogen receptor; estradiol; external cavity laser; photonic crystal; X-linked inhibitor of apoptosis protein (XIAP); SM-164

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APA (6th Edition):

Flood, T. (2013). Advances in high-throughput screening: better compounds, novel targets, enhanced sensors. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44780

Chicago Manual of Style (16th Edition):

Flood, Timothy. “Advances in high-throughput screening: better compounds, novel targets, enhanced sensors.” 2013. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/44780.

MLA Handbook (7th Edition):

Flood, Timothy. “Advances in high-throughput screening: better compounds, novel targets, enhanced sensors.” 2013. Web. 19 Sep 2019.

Vancouver:

Flood T. Advances in high-throughput screening: better compounds, novel targets, enhanced sensors. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2013. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/44780.

Council of Science Editors:

Flood T. Advances in high-throughput screening: better compounds, novel targets, enhanced sensors. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44780


University of Illinois – Urbana-Champaign

21. Luu, Long Minh. Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy.

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

 Myotonic dystrophy type 1 (DM1), the most common form of adult-onset muscular dystrophy, is an incurable neuromuscular disease. DM1 is caused by an expansion of… (more)

Subjects/Keywords: Myotonic Dystrophy; RNA binder; Click chemistry

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APA (6th Edition):

Luu, L. M. (2016). Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/95555

Chicago Manual of Style (16th Edition):

Luu, Long Minh. “Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/95555.

MLA Handbook (7th Edition):

Luu, Long Minh. “Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy.” 2016. Web. 19 Sep 2019.

Vancouver:

Luu LM. Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/95555.

Council of Science Editors:

Luu LM. Approaches to the assembly of potent therapeutic agents for the treatment of myotonic dystrophy. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/95555


University of Illinois – Urbana-Champaign

22. Zhang, Meng. External cavity laser biosensor for label-free detection.

Degree: PhD, Physics, 2015, University of Illinois – Urbana-Champaign

 Optical label-free biosensors serve as a powerful detection tool to analyze biomolecular interactions, and have been widely used in pharmaceutical drug discovery and biochemical sensing.… (more)

Subjects/Keywords: optical biosensor; tunable laser

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APA (6th Edition):

Zhang, M. (2015). External cavity laser biosensor for label-free detection. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/78590

Chicago Manual of Style (16th Edition):

Zhang, Meng. “External cavity laser biosensor for label-free detection.” 2015. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/78590.

MLA Handbook (7th Edition):

Zhang, Meng. “External cavity laser biosensor for label-free detection.” 2015. Web. 19 Sep 2019.

Vancouver:

Zhang M. External cavity laser biosensor for label-free detection. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2015. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/78590.

Council of Science Editors:

Zhang M. External cavity laser biosensor for label-free detection. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2015. Available from: http://hdl.handle.net/2142/78590


University of Illinois – Urbana-Champaign

23. Nguyen, Lien Thi Thuy. Design, synthesis, and biological activities of small molecules that target myotonic dystrophy.

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

 Myotonic dystrophy (DM) is a triple-repeat expansion, multi-systemic disease that affects one in eight thousand people worldwide. The cause of the disease is a progressive,… (more)

Subjects/Keywords: Myotonic Dystrophy; Drug development

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APA (6th Edition):

Nguyen, L. T. T. (2016). Design, synthesis, and biological activities of small molecules that target myotonic dystrophy. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/90730

Chicago Manual of Style (16th Edition):

Nguyen, Lien Thi Thuy. “Design, synthesis, and biological activities of small molecules that target myotonic dystrophy.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/90730.

MLA Handbook (7th Edition):

Nguyen, Lien Thi Thuy. “Design, synthesis, and biological activities of small molecules that target myotonic dystrophy.” 2016. Web. 19 Sep 2019.

Vancouver:

Nguyen LTT. Design, synthesis, and biological activities of small molecules that target myotonic dystrophy. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/90730.

Council of Science Editors:

Nguyen LTT. Design, synthesis, and biological activities of small molecules that target myotonic dystrophy. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/90730


University of Illinois – Urbana-Champaign

24. Wang, Yang. Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections.

Degree: PhD, Chemistry, 2016, University of Illinois – Urbana-Champaign

 The drug resistance has become a big threat to human health, and there is currently a dearth of new antibiotics being introduced. In order to… (more)

Subjects/Keywords: undecaprenyl synthesis; Staphylococcus aureus; Trypanosoma brucei

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APA (6th Edition):

Wang, Y. (2016). Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/90768

Chicago Manual of Style (16th Edition):

Wang, Yang. “Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections.” 2016. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/90768.

MLA Handbook (7th Edition):

Wang, Yang. “Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections.” 2016. Web. 19 Sep 2019.

Vancouver:

Wang Y. Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2016. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/90768.

Council of Science Editors:

Wang Y. Multi-target drug discovery against Staphylococcus aureus and Trypanosoma brucei infections. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2016. Available from: http://hdl.handle.net/2142/90768


University of Illinois – Urbana-Champaign

25. Muehl, Ellen Marissa. Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators.

Degree: PhD, Chemistry, 2017, University of Illinois – Urbana-Champaign

 Reactions that occur at the cell membrane are varied and critical for many biological functions. When soluble proteins interact with the cell surface, the crowded… (more)

Subjects/Keywords: Protein-lipid interactions; Nanodisc; Silicon photonic microring resonators; Blood coagulation

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APA (6th Edition):

Muehl, E. M. (2017). Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/97403

Chicago Manual of Style (16th Edition):

Muehl, Ellen Marissa. “Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators.” 2017. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/97403.

MLA Handbook (7th Edition):

Muehl, Ellen Marissa. “Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators.” 2017. Web. 19 Sep 2019.

Vancouver:

Muehl EM. Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2017. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/97403.

Council of Science Editors:

Muehl EM. Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2017. Available from: http://hdl.handle.net/2142/97403


University of Illinois – Urbana-Champaign

26. Wilson, Tyler. Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition.

Degree: PhD, 0335, 2012, University of Illinois – Urbana-Champaign

 The activation of Lewis acids by chiral Lewis bases has allowed for the development of a robust and highly selective catalyst system for the addition… (more)

Subjects/Keywords: Silyl Ketene Imines; Lewis Base Catalysis; Enantioselective Synthesis

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APA (6th Edition):

Wilson, T. (2012). Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/29486

Chicago Manual of Style (16th Edition):

Wilson, Tyler. “Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/29486.

MLA Handbook (7th Edition):

Wilson, Tyler. “Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition.” 2012. Web. 19 Sep 2019.

Vancouver:

Wilson T. Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/29486.

Council of Science Editors:

Wilson T. Synthesis, study and application of silyl ketene imines in Lewis base catalyzed carbonyl addition. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/29486


University of Illinois – Urbana-Champaign

27. West, Diana. The discovery and characterization of anticancer procaspase activating compounds.

Degree: PhD, 0335, 2012, University of Illinois – Urbana-Champaign

 One key hallmark of cancer is its ability to evade apoptotic cell death. In normal cells, the apoptotic intrinsic and extrinsic pathways converge on the… (more)

Subjects/Keywords: Apoptosis; Procaspase activation to induce cell death; Procaspase; Small molecule activators of Procaspase-3/-7; PAC-1

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APA (6th Edition):

West, D. (2012). The discovery and characterization of anticancer procaspase activating compounds. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/29499

Chicago Manual of Style (16th Edition):

West, Diana. “The discovery and characterization of anticancer procaspase activating compounds.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/29499.

MLA Handbook (7th Edition):

West, Diana. “The discovery and characterization of anticancer procaspase activating compounds.” 2012. Web. 19 Sep 2019.

Vancouver:

West D. The discovery and characterization of anticancer procaspase activating compounds. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/29499.

Council of Science Editors:

West D. The discovery and characterization of anticancer procaspase activating compounds. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/29499


University of Illinois – Urbana-Champaign

28. Lemkau, Luisel. A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein.

Degree: PhD, 0335, 2012, University of Illinois – Urbana-Champaign

 α-Synuclein (AS) fibrils are the main component of Lewy bodies, filamentous inclusions known as the pathological hallmark of Parkinson’s disease (PD). The normal function, toxic… (more)

Subjects/Keywords: solid-state-NMR; mutants; low pH; metals

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APA (6th Edition):

Lemkau, L. (2012). A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/29574

Chicago Manual of Style (16th Edition):

Lemkau, Luisel. “A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein.” 2012. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/29574.

MLA Handbook (7th Edition):

Lemkau, Luisel. “A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein.” 2012. Web. 19 Sep 2019.

Vancouver:

Lemkau L. A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2012. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/29574.

Council of Science Editors:

Lemkau L. A comparison of resultant fibrils upon environmental and sequential manipulations of α-synuclein, a Parkinson’s disease associated protein. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2012. Available from: http://hdl.handle.net/2142/29574


University of Illinois – Urbana-Champaign

29. Haghighat Jahromi, Amin. Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment.

Degree: PhD, 0319, 2013, University of Illinois – Urbana-Champaign

 Myotonic dystrophy type 1 (DM1) is caused by an expanded CUG repeat (CUGexp) that sequesters muscleblind-like 1 protein (MBNL1), a protein that regulates alternative splicing.… (more)

Subjects/Keywords: Myotonic Dystrophy; Drug discovery; MBNL1-CUGexp interaction

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APA (6th Edition):

Haghighat Jahromi, A. (2013). Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/44815

Chicago Manual of Style (16th Edition):

Haghighat Jahromi, Amin. “Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment.” 2013. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/44815.

MLA Handbook (7th Edition):

Haghighat Jahromi, Amin. “Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment.” 2013. Web. 19 Sep 2019.

Vancouver:

Haghighat Jahromi A. Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2013. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/44815.

Council of Science Editors:

Haghighat Jahromi A. Advances in myotonic dystrophy type 1 drug discovery through design of novel ligands and mechanism establishment. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2013. Available from: http://hdl.handle.net/2142/44815


University of Illinois – Urbana-Champaign

30. Bemis, Christopher Yngwie. Synthesis of sesquiterpene-tropolones.

Degree: PhD, Chemistry, 2019, University of Illinois – Urbana-Champaign

 A modular synthetic platform for the synthesis of the multi-bioactive sesquiterpene-tropolone natural products has been developed in an effort to provide general synthetic access to… (more)

Subjects/Keywords: total synthesis; organic synthesis; sesquiterpene-tropolones; meroterpenoids; tropolone; pycnidione; epolone A; epolone B; eupenifeldin

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APA (6th Edition):

Bemis, C. Y. (2019). Synthesis of sesquiterpene-tropolones. (Doctoral Dissertation). University of Illinois – Urbana-Champaign. Retrieved from http://hdl.handle.net/2142/104826

Chicago Manual of Style (16th Edition):

Bemis, Christopher Yngwie. “Synthesis of sesquiterpene-tropolones.” 2019. Doctoral Dissertation, University of Illinois – Urbana-Champaign. Accessed September 19, 2019. http://hdl.handle.net/2142/104826.

MLA Handbook (7th Edition):

Bemis, Christopher Yngwie. “Synthesis of sesquiterpene-tropolones.” 2019. Web. 19 Sep 2019.

Vancouver:

Bemis CY. Synthesis of sesquiterpene-tropolones. [Internet] [Doctoral dissertation]. University of Illinois – Urbana-Champaign; 2019. [cited 2019 Sep 19]. Available from: http://hdl.handle.net/2142/104826.

Council of Science Editors:

Bemis CY. Synthesis of sesquiterpene-tropolones. [Doctoral Dissertation]. University of Illinois – Urbana-Champaign; 2019. Available from: http://hdl.handle.net/2142/104826

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