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You searched for +publisher:"University of Illinois – Chicago" +contributor:("Prasad, Bharati"). One record found.

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University of Illinois – Chicago

1. Stache, Rutger Wolfgang. Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study.

Degree: 2019, University of Illinois – Chicago

URL: http://hdl.handle.net/10027/23864 

Hypothesis: Augmentation of a mandibular advancement oral appliance (OA) by pharmacotherapy (ondansetron+fluoxetine) will increase therapeutic efficacy in moderate to severe obstructive sleep apnea (OSA) patients. Methods: Fifteen subjects met inclusion criteria and were enrolled. Subjects with moderate-severe OSA were treated with a TAP3 Elite® OA plus placebo medication for two weeks, followed by a combination regimen of ondansetron (24 mg/day) and fluoxetine (10 mg/day) with continued use of the OA for four weeks. Results: Seven subjects (5 male and 2 female, BMI 39.1±6.6) completed the study. AHI OA + Medications (22.1±16.3) was lower than the AHI baseline (31.7±11.2). Sleep efficiency and oxygen desaturation indices improved. Subjective (ESS) and objective (PVT) daytime sleepiness showed improvement. Mean total airway volume at end inspiration increased by 35% with OA compared to without OA. Minimum cross sectional area (CSA) increased by 48.8% with OA compared to without OA Conclusions: Combination of pharmacotherapy and oral appliance maybe a viable option in treating patients with moderate to severe OSA. Advisors/Committee Members: Galang-Boquiren, Maria Therese S (advisor), Viana, Grace (committee member), Prasad, Bharati (committee member), Galang-Boquiren, Maria Therese S (chair).

Subjects/Keywords: OSA; Orthodontics; Obstructive sleep apnea

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Stache, R. W. (2019). Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study. (Thesis). University of Illinois – Chicago. Retrieved from http://hdl.handle.net/10027/23864

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Stache, Rutger Wolfgang. “Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study.” 2019. Thesis, University of Illinois – Chicago. Accessed April 12, 2021. http://hdl.handle.net/10027/23864.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Stache, Rutger Wolfgang. “Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study.” 2019. Web. 12 Apr 2021.

Vancouver:

Stache RW. Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study. [Internet] [Thesis]. University of Illinois – Chicago; 2019. [cited 2021 Apr 12]. Available from: http://hdl.handle.net/10027/23864.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Stache RW. Oral Appliance and Pharmacological Agents in the Treatment of Sleep Apnea: A Pilot Clinical Study. [Thesis]. University of Illinois – Chicago; 2019. Available from: http://hdl.handle.net/10027/23864

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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