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You searched for +publisher:"University of Helsinki, Helsinki Institute of Physics" +contributor:("Helsinki Institute of Physics"). One record found.

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1. Terämä, Emma. Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation.

Degree: 2007, University of Helsinki, Helsinki Institute of Physics

The thesis focuses on the transport of polar biomolecules and colloid particles studied through atomistic and coarse-grained simulation techniques. The thesis is comprised of two themes complementing one another. First we concentrate on the structural and dynamical aspects of alcohol molecules in lipid bilayers with varying degree of unsaturation. Second, the thesis employs dielectrophoresis to elucidate the non-equilibrium transport phenomena of nano-sized colloidal particles. The former is an example of simulating a molecular system at the atomic level, providing insight into the mechanism of anesthetics such as alcohols. The latter topic exemplifies the more coarse grained approach of describing surface polarization effects of a colloid coupled to a varying external electric field and subsequent transport of the colloid. In water solution the lipids self-organize into bilayer structures depicting biological membranes. The effect of ethanol and methanol solvents on the lipid bilayer structure and dynamics was investigated. Simulations show ethanol transport into and through the bilayer, results indicating an undisputable effect of alcohols, esp. ethanol, on membrane properties. Hydrogen bonding between lipid and alcohol molecules is observed, and lipid bilayer pressure profile changes due to alcohol are obtained. For dielectrophoresis, novel computational models for the transport of (nano-sized) colloidal particles in non-homogeneous electric fields are developed. The model's coupling strength depends on field strength, colloid charge magnitude and charge distribution, which in real life also affect the general characteristics of (surface) conductivity and permittivity that evoke dielectrophoretic behavior of e.g. cells. The colloids in simulation are shown to be affected by their medium via Brownian motion and hydrodynamics. It is demonstrated that aggregation of nano-sized colloids can enhance their transport.

Internal report / Helsinki Institute of Physics, ISSN 1455-0563; 2006-09

Advisors/Committee Members: Helsinki University of Technology, Department of Engineering Physics and Mathematics, Laboratory of Physics, Helsinki Institute of Physics.

Subjects/Keywords: lipid membrane; dielectrophoresis; molecular dynamics

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APA (6th Edition):

Terämä, E. (2007). Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation. (Thesis). University of Helsinki, Helsinki Institute of Physics. Retrieved from http://lib.tkk.fi/Diss/2007/isbn9521029633/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Chicago Manual of Style (16th Edition):

Terämä, Emma. “Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation.” 2007. Thesis, University of Helsinki, Helsinki Institute of Physics. Accessed October 21, 2019. http://lib.tkk.fi/Diss/2007/isbn9521029633/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

MLA Handbook (7th Edition):

Terämä, Emma. “Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation.” 2007. Web. 21 Oct 2019.

Vancouver:

Terämä E. Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation. [Internet] [Thesis]. University of Helsinki, Helsinki Institute of Physics; 2007. [cited 2019 Oct 21]. Available from: http://lib.tkk.fi/Diss/2007/isbn9521029633/.

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

Council of Science Editors:

Terämä E. Transport Phenomena of Polar Biomolecules and Colloids, Perspectives Through Simulation. [Thesis]. University of Helsinki, Helsinki Institute of Physics; 2007. Available from: http://lib.tkk.fi/Diss/2007/isbn9521029633/

Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

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