+publisher:"University of Florida" +contributor:("Kautz, Steven A.")

University of Florida

1. Bowden, Mark. Measurement of Activity Specific Behavioral Recovery in Chronic Stroke.

Degree: PhD, Rehabilitation Science, 2009, University of Florida

► Current examinations of post-stroke motor control rely on interpretation of isolated movements performed during standardardized clinical examinations. Due to the complexity of human walking, however,… (more)

▼ Current examinations of post-stroke motor control rely on interpretation of isolated movements performed during standardardized clinical examinations. Due to the complexity of human walking, however, evaluation of walking specific motor control likely needs to be conducted as the patient is ambulating. Task specific evaluations may enhance the ability of the clinician to distinguish recovery of functional behavior by means of compensation for motor control deficits from true restitution of walking specific motor control. The purpose of this dissertation is to examine assessments by which individuals post stroke may be examined during walking in order to distinguish restitution of physical function from compensatory responses. Current clinical examinations do not differentiate motor activity during the task or in walking and correlate poorly with functional and biomechanical walking performance measures. Factor analysis of electromyographic motor patterns, however, yields specific modules of activity that correlate significantly with each of the examined walking performance measures. Voluntary, discrete activities may be inadequate to capture the complex motor behavior in walking, and walking specific measures are required to describe the efficacy of rehabilitation on behavioral recovery. One such measure is derived from the anterior-posterior ground reaction forces generated during walking. These forces are responsible for the propulsion of the center of mass anteriorly and we propose a measure (paretic propulsion) that allows for examination of the paretic leg contribution to overall propulsion. This measure is positively correlated both with speed and with severity of hemiparesis. Perhaps most importantly, paretic propulsion allows the investigator to distinguish functional compensation from physiological restitution by providing a measure of coordinated output of the paretic leg. Additionally, we assessed measures of spinal level reflex activity to examine the degree to which those with post stroke hemiparesis modulate sensory input. While healthy controls modulate in a systematic and reproducible fashion, those with stroke demonstrate substantially more variable responses. We determined that paretic leg responses differ depending on side stimulated, indicating that stroke leads to altered function at the level of the spinal cord during gait. Further exploration is required to fully understand the motor control and clinical implications. ( en ) Advisors/Committee Members: Kautz, Steven A. (committee chair), Rosenbek, John C. (committee member), Kleim, Jeffrey (committee member).

Subjects/Keywords: Electromyography; Gait; Legs; Paresis; Propulsion; Reflexes; Speed; Spinal cord; Strokes; Walking; biomechanics, emg, motor, reflexes, stoke, walking

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APA (6^th Edition):

Bowden, M. (2009). Measurement of Activity Specific Behavioral Recovery in Chronic Stroke. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0024258

Chicago Manual of Style (16^th Edition):

Bowden, Mark. “Measurement of Activity Specific Behavioral Recovery in Chronic Stroke.” 2009. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0024258.

MLA Handbook (7^th Edition):

Bowden, Mark. “Measurement of Activity Specific Behavioral Recovery in Chronic Stroke.” 2009. Web. 22 Feb 2019.

Vancouver:

Bowden M. Measurement of Activity Specific Behavioral Recovery in Chronic Stroke. [Internet] [Doctoral dissertation]. University of Florida; 2009. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0024258.

Council of Science Editors:

Bowden M. Measurement of Activity Specific Behavioral Recovery in Chronic Stroke. [Doctoral Dissertation]. University of Florida; 2009. Available from: http://ufdc.ufl.edu/UFE0024258

University of Florida

2. Day, Kristin. Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury.

Degree: PhD, Rehabilitation Science, 2010, University of Florida

URL: http://ufdc.ufl.edu/UFE0041469

► Dynamic stability, defined as the ability to control one's center-of-mass (CoM) within a moving base-of-support, is a co-requisite of functional walking. Following a spinal cord… (more)

▼ Dynamic stability, defined as the ability to control one's center-of-mass (CoM) within a moving base-of-support, is a co-requisite of functional walking. Following a spinal cord injury (SCI), dynamic stability is impaired. One clinical approach for dynamic stability deficits utilizes assistive devices (ADs) to compensate for functional losses post-SCI. However, SCI rehabilitation has recently begun a transition from compensatory therapies toward activity-based therapies, which target walking recovery. To remain consistent with this therapeutic shift, measurements should be conducted in this same recovery context. Therefore, the purpose of this dissertation was to examine movements that individuals with SCI employ to maintain dynamic stability using a framework that parallels the rehabilitation paradigm shift. Measurements utilized were based on scientific evidence of nervous system priorities to maintain stability. The first experiment investigated head stability during walking with and without devices to understand the effect of ADs, as a conventional evaluation approach, on head stability. Additionally, this study aimed to determine how head stability differed between individuals after injury walking without ADs and healthy persons. This testing condition without devices remained through subsequent studies. The second experiment examined dynamic stability via foot placement analysis relative to the 1) opposite foot, 2) CoM, and 3) CoM plus its velocity. Finally, the third experiment assessed the differential effects of manual-assisted and robotic-assisted locomotor training on dynamic stability. CoM trajectory length per stride was used as a primary indicator of stability control with trunk motion and spatial foot parameters examined as secondary outcomes. Collective findings across studies indicated that 1) ADs have a role in head stability, and when ADs are removed, individuals post-injury exhibit less stability than controls; 2) persons with SCI demonstrate greater variability in all measures of foot placement compared to controls and appear to maintain stability through a continuous pattern of corrective foot placements; and 3) both manual-assisted and robotic-assistive locomotor interventions have training benefits for dynamic stability, but the trunk and feet strategies used to maintain CoM control vary between interventions. This work is a first step in dynamic stability analysis post-SCI and lays the groundwork for further investigations in this field. ( en ) Advisors/Committee Members: Behrman, Andrea L. (committee chair), Kautz, Steven A. (committee member), Velozo, Craig A. (committee member), Howland, Dena R. (committee member).

Subjects/Keywords: Dynamic stability; Feet; Gait; Head; Pelvis; Physical trauma; Self help devices; Spinal cord; Treadmills; Walking; balance, control, cord, gait, injury, locomotion, motor, recovery, sci, spinal, stability, walking

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APA (6^th Edition):

Day, K. (2010). Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0041469

Chicago Manual of Style (16^th Edition):

Day, Kristin. “Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury.” 2010. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0041469.

MLA Handbook (7^th Edition):

Day, Kristin. “Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury.” 2010. Web. 22 Feb 2019.

Vancouver:

Day K. Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury. [Internet] [Doctoral dissertation]. University of Florida; 2010. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0041469.

Council of Science Editors:

Day K. Motor Control Solutions to Dynamic Stability Deficits during Walking after Spinal Cord Injury. [Doctoral Dissertation]. University of Florida; 2010. Available from: http://ufdc.ufl.edu/UFE0041469

University of Florida

3. Nott, Cameron. Angular Momentum During Gait - A Computational Simulation.

Degree: PhD, Mechanical Engineering - Mechanical and Aerospace Engineering, 2010, University of Florida

URL: http://ufdc.ufl.edu/UFE0042119

► There is a 73% incidence of falls among individuals with mild to moderate stroke. 37% of patients that fall sustain injury that required medical treatment.… (more)

▼ There is a 73% incidence of falls among individuals with mild to moderate stroke. 37% of patients that fall sustain injury that required medical treatment. 8% sustained fractures and the risk for hip fracture is ten times higher in the stroke population. General risk of fracture is two to seven times greater following a stroke. Due to the impact falls have on the health and well being of persons with stroke, there is a substantial need to assess dynamic balance during walking in order to ascertain who is at increased risk for falls. While little has been done to quantify balance during walking in the general population, much less has been done to quantify the effect of neurological impairment on balance during gait in persons with stroke. Approaches for determining who is at risk for falls have usually relied on clinical measurement scales as opposed to quantitative evaluation of joint power production ability. However, interpretations of these measures are based on statistical evidence and do not quantify a subject's balance performance during walking. To quantify and ultimately improve dynamic balance during neurologically impaired walking, it is necessary to quantify the biomechanical effects of altered or impaired joint power productions during paretic gait. These effects are relevant since a primary disability associated with post-stroke hemiparesis is the failure to make rapid graded adjustment of muscle forces. Reduction in, or ill coordinated, muscle forces result in inefficient and ineffective net joint power production. In order to quantify the biomechanical effects related to a decrease in joint power production, a detailed biomechanical simulation of the human body during perturbed walking is necessary to elaborate on experimental findings. A simulation that can explore the effects of reduced power production on balance requires the development of a ground contact model that can explain the production of ground reaction forces and moments based on the deformation/kinematics of the foot. The following work develops the ground contact model and the biomechanical simulation that mathematically relates reduction in joint power production to deficits in balance. Furthermore, the work investigates the role of various joints in maintaining balance and quantifies successful balance with a mathematical measure: whole body angular momentum. To improve understanding of the relation between joint power production and balance, the simulation is subjected to an optimization procedure that results in kinematic and kinetic solutions that return whole body angular momentum to a regular limit cycle following a perturbation. Studying the return of whole body angular momentum to a regular limit cycle after a perturbation assists in understanding balance since whole body angular momentum collectively quantifies rotational velocity of the entire body about the center of mass and in order to maintain balance, the rotational velocity of the entire body is necessarily bounded. ( en ) Advisors/Committee Members: Fregly, Benjamin J. (committee chair), Dixon, Warren E. (committee member), Banks, Scott A. (committee member), Kautz, Steven A. (committee member).

Subjects/Keywords: Angular acceleration; Angular momentum; Feet; Foot joints; Gait; Kinematics; Modeling; Simulations; Treadmills; Walking; computational, gait, generation, power, simulation

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APA (6^th Edition):

Nott, C. (2010). Angular Momentum During Gait - A Computational Simulation. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0042119

Chicago Manual of Style (16^th Edition):

Nott, Cameron. “Angular Momentum During Gait - A Computational Simulation.” 2010. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0042119.

MLA Handbook (7^th Edition):

Nott, Cameron. “Angular Momentum During Gait - A Computational Simulation.” 2010. Web. 22 Feb 2019.

Vancouver:

Nott C. Angular Momentum During Gait - A Computational Simulation. [Internet] [Doctoral dissertation]. University of Florida; 2010. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0042119.

Council of Science Editors:

Nott C. Angular Momentum During Gait - A Computational Simulation. [Doctoral Dissertation]. University of Florida; 2010. Available from: http://ufdc.ufl.edu/UFE0042119

University of Florida

4. Fox,Emily J. Locomotor Control and Recovery After Human Spinal Cord Injury.

Degree: PhD, Rehabilitation Science, 2011, University of Florida

URL: http://ufdc.ufl.edu/UFE0043293

► Animal studies indicate that walking and locomotor behaviors are partially controlled by oscillating spinal networks responsive to task-specific sensory input. Furthermore, the nervous system may… (more)

Subjects/Keywords: Electromyography; Gait; Kinematics; Legs; Locomotion; Lower extremity; Physical trauma; Spinal cord; Treadmills; Walking; activation – biomechanics – children – cpgs – gait – locomotor – lt – modules – muscle – recovery – rehabilitation – sci – spinal – spinalcord – training – walking

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

J, F. (2011). Locomotor Control and Recovery After Human Spinal Cord Injury. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0043293

Chicago Manual of Style (16^th Edition):

J, Fox,Emily. “Locomotor Control and Recovery After Human Spinal Cord Injury.” 2011. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0043293.

MLA Handbook (7^th Edition):

J, Fox,Emily. “Locomotor Control and Recovery After Human Spinal Cord Injury.” 2011. Web. 22 Feb 2019.

Vancouver:

J F. Locomotor Control and Recovery After Human Spinal Cord Injury. [Internet] [Doctoral dissertation]. University of Florida; 2011. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0043293.

Council of Science Editors:

J F. Locomotor Control and Recovery After Human Spinal Cord Injury. [Doctoral Dissertation]. University of Florida; 2011. Available from: http://ufdc.ufl.edu/UFE0043293

University of Florida

5. Blum, Adele. Plasticity of the central nervous system and functional recovery following spinal cord injury.

Degree: PhD, Medical Sciences - Neuroscience (IDP), 2010, University of Florida

URL: http://ufdc.ufl.edu/UFE0041439

► The focus of these studies was on plasticity of the central nervous system and functional recovery following a low thoracic hemisection in the cat. Functional… (more)

▼ The focus of these studies was on plasticity of the central nervous system and functional recovery following a low thoracic hemisection in the cat. Functional recovery was assessed by characterizing the obstacle negotiation task which can be achieved using supraspinal and/or intraspinal networks for voluntary clearance or the stumbling corrective response respectively. Following thoracic hemisection, significant changes were seen in the cat s ability to clear an obstacle and the partial recovery seen suggested underlying plasticity was likely. To identify potential substrates that may contribute to the recovery, populations of neurons that bridged the lesion segment were identified using a retrograde tracer. Populations of long and short propriospinal neurons (PSNs) and rubrospinal tract (RST) neurons were assessed. All systems showed an immediate, significant decrease in the number of neurons with axons below the level of the lesion. The decrease was permanent in the long PSNs. However, the number of short PSNs increased significantly post-injury. The number of neurons contralateral to the lesion was significantly greater than that seen in normal controls suggesting that in addition to regeneration and collateral sprouting of axons in passage, neurons with axons that normally terminate rostral to the lesion were extending branches bridging the lesion site. Similar significant changes were seen in the non-axotomized red nucleus. These neurons represent a novel substrate that may have contributed to new circuitry which supported the functional recovery seen. Traditionally, studies focus on the lesion environment when identifying substrates that inhibit axonal growth following injury. However, areas distant to the lesion undergo Wallerian degeneration. To understand how this may affect the distant spinal substrates, the glial responses and extracellular matrix changes in the cervical and lumbar spinal cord following a thoracic injury were assessed. Using immunohistochemical techniques, increases in activated glial cells as well as chondroitin sulfate proteoglycans were identified in areas undergoing Wallerian degeneration. Furthermore, these changes were delayed with respect to the timing of these same changes at the lesion site. This identifies the importance of considering injury-induced changes in substrates distant to the lesion when assessing plasticity and designing treatments to promote long distance regeneration. Understanding the potential for plasticity and the putative impact of cellular and extracellular matrix changes along the length of the spinal cord following injury are important to understand recovery that is seen and critical to the development of therapeutic interventions to enhance functional recovery. ( en ) Advisors/Committee Members: Howland, Dena R. (committee chair), Behrman, Andrea L. (committee member), Reier, Paul J. (committee member), Thompson, Floyd J. (committee member), Kautz, Steven A. (committee member).

Subjects/Keywords: Axons; Lesions; Locomotion; Materials recovery; Myelin; Neurons; Physical trauma; Rats; Scars; Spinal cord

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Blum, A. (2010). Plasticity of the central nervous system and functional recovery following spinal cord injury. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0041439

Chicago Manual of Style (16^th Edition):

Blum, Adele. “Plasticity of the central nervous system and functional recovery following spinal cord injury.” 2010. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0041439.

MLA Handbook (7^th Edition):

Blum, Adele. “Plasticity of the central nervous system and functional recovery following spinal cord injury.” 2010. Web. 22 Feb 2019.

Vancouver:

Blum A. Plasticity of the central nervous system and functional recovery following spinal cord injury. [Internet] [Doctoral dissertation]. University of Florida; 2010. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0041439.

Council of Science Editors:

Blum A. Plasticity of the central nervous system and functional recovery following spinal cord injury. [Doctoral Dissertation]. University of Florida; 2010. Available from: http://ufdc.ufl.edu/UFE0041439

University of Florida

6. Barak, Sharon. Habitual Ambulatory Activity Measurement Post-stroke.

Degree: PhD, Rehabilitation Science, 2009, University of Florida

URL: http://ufdc.ufl.edu/UFE0024289

► This study had four main objectives: (1) to assess the rate of and predictors for inferred compliance with lower extremity Step Activity Monitor (SAM) protocol,… (more)

▼ This study had four main objectives: (1) to assess the rate of and predictors for inferred compliance with lower extremity Step Activity Monitor (SAM) protocol, (2) to assess the relationship between gait speed and SAM derived home and community ambulation, (3) to examine the association of gait speed and SAM indices to mobility and social participation domains of the Stroke Impact Scale (SIS), and (4) to identify predictors of SAM derived home and community ambulation. Data in this study were derived from the Locomotor Experience Applied Post-Stroke (LEAPS) trail. Study participants consisted of individuals two-month post-stroke with moderate to severe gait impairment. The results indicated high compliance rates in the first and second measurement days (72 and 66%, respectively). However, only 54% of the participants complied with the SAM protocol in both measurement days. Older age, less severe balance control deficits, and moderate to high balance self-efficacy, predicted increased compliance. In addition, self-selected walking speed significantly correlated with step activity volume, most activity intensity indices, and one activity pattern outcome. However, balance control, walking endurance, lower extremity motor control, and balance self-efficacy distorted the association between walking speed and SAM outcomes. In addition, gait speed and certain SAM indices significantly correlated with both SIS mobility and participation. Surprisingly, gait speed association with SIS was stronger than the association of numerous SAM indices with SIS. Balance control, walking endurance, executive function, stroke location, age, balance self-efficacy, lower extremity motor control, and gait speed were all identified as home and community ambulation predictors. However, gait speed did not predict activity volume or important activity pattern outcomes such as activity randomness. Moreover, this model explained only up to 50% of the variation in SAM derived step activity. Therefore, other factors such as caregiver support may also contribute to home and community ambulation. In conclusion, walking in the real world is highly complex. Furthermore, for individuals at two months post-stroke, usual gait-speed does not associate with all the various aspects of home and community ambulation. However, the association of gait speed with home and community ambulation may be affected by the time since stroke. ( en ) Advisors/Committee Members: Behrman, Andrea L. (committee chair), Kautz, Steven A. (committee member), Rosenbek, John C. (committee member), Wu, Samuel S. (committee member), Duncan, Pamela W. (committee member).

Subjects/Keywords: Accelerometers; Ambulation; Community life; Exercise; Gait; Guideline adherence; Lower extremity; Older adults; Strokes; Walking; accelerometer, ambulation, gait, measurement, recovery, stroke

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APA (6^th Edition):

Barak, S. (2009). Habitual Ambulatory Activity Measurement Post-stroke. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0024289

Chicago Manual of Style (16^th Edition):

Barak, Sharon. “Habitual Ambulatory Activity Measurement Post-stroke.” 2009. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0024289.

MLA Handbook (7^th Edition):

Barak, Sharon. “Habitual Ambulatory Activity Measurement Post-stroke.” 2009. Web. 22 Feb 2019.

Vancouver:

Barak S. Habitual Ambulatory Activity Measurement Post-stroke. [Internet] [Doctoral dissertation]. University of Florida; 2009. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0024289.

Council of Science Editors:

Barak S. Habitual Ambulatory Activity Measurement Post-stroke. [Doctoral Dissertation]. University of Florida; 2009. Available from: http://ufdc.ufl.edu/UFE0024289

University of Florida

7. Jefferson, Stephanie. Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex.

Degree: PhD, Medical Sciences - Neuroscience (IDP), 2009, University of Florida

URL: http://ufdc.ufl.edu/UFE0023767

► Chondroitin sulfate proteoglycans (CSPGs) are potent inhibitors of neuronal growth following spinal cord injury (SCI). Digestion of CSPGs with Chondroitinase ABC (Ch'ase ABC) has been… (more)

▼ Chondroitin sulfate proteoglycans (CSPGs) are potent inhibitors of neuronal growth following spinal cord injury (SCI). Digestion of CSPGs with Chondroitinase ABC (Ch'ase ABC) has been shown to significantly decrease their inhibitory properties in vitro and enhance axonal growth and promote recovery of locomotion in rodent models and our feline model of SCI. This study assessed the effects of intraspinal Ch'ase ABC delivery following low thoracic hemisection in the adult cat across motor tasks that are mediated by diverse levels of the neural axis. Adult cats received a left spinal T10 hemisection (hx) alone, hx+vehicle control or hx+Ch'ase ABC repeatedly delivered to the lesion site via a port system. Motor performance was assessed pre and post-injury over the course of 20 weeks during basic as well as skilled locomotion and during coughing. Two weeks following the last behavioral data collection point, fluorogold (FG) was injected bilaterally into the spinal cord caudal to the T10 hx. Specific components of the gait cycle such as the step cycle duration, swing and stance duration, knee flexion during swing, and paw drag were differentially affected during bipedal treadmill and overground locomotion following injury. Ch'ase ABC treatment did not significally affect these characteristics assessed during bipedal treadmill or overground locomotion. Ch'ase ABC treatment significantly improved skilled pegboard locomotion. Ch'ase ABC treated cats were able to place their affected hindlimbs on the pegboard earlier and more frequently than SCI-only cats and developed a unique hindlimb motor strategy that differed from the one used prior to injury. To determine if Ch'ase ABC has an effect across diverse motor systems, the cough reflex also was assessed. The general characteristics of cough were not affected by our lesion paradigm as no changes in the parameters evaluated were seen post-hemisection. However, Ch'ase ABC treated cats showed a significant increase in esophageal pressure amplitudes above pre-injury values. In addition to behavioral improvements and changes, Ch'ase ABC also enhanced axonal plasticity. pNF-H immunoreactivity below the injury site, as well as retrogradely labeled neurons in the contralateral red nucleus, were significantly greater in cats treated with Ch'ase ABC than in controls. The findings presented are the first to demonstrate that Ch'ase ABC treatment can enhance skilled locomotor behavior, axonal growth, and cough esophageal pressures within the same animals. They also are the first to show that Ch'ase ABC can promote plasticity of anatomical substrates likely to underlie improvements observed in recovery of locomotor behavior following SCI in a large translational animal model. ( en ) Advisors/Committee Members: Howland, Dena R. (committee chair), Behrman, Andrea L. (committee member), Bolser, Donald C. (committee member), Reier, Paul J. (committee member), Kautz, Steven A. (committee member).

Subjects/Keywords: Axons; Brain; Cough; Lesions; Locomotion; Neurons; Physical trauma; Rats; Spinal cord; Treadmills; abdominis, axonal, basic, behavioral, bipedal, chondroitin, chondroitinase, cord, cough, cycle, drag, electromyogram, esophageal, feline, fluorogold, gait, growth, hemisection, hindlimb, injury, ipsilateral, locomotion, neurofilament, overground, paw, pegboard, plasticity, pressure, proteoglycan, recovery, rectus, reflex, rubrospinal, skilled, spinal, sulfate, supraspinal, synaptophysin, thoracic, tracing, tract

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Jefferson, S. (2009). Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0023767

Chicago Manual of Style (16^th Edition):

Jefferson, Stephanie. “Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex.” 2009. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0023767.

MLA Handbook (7^th Edition):

Jefferson, Stephanie. “Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex.” 2009. Web. 22 Feb 2019.

Vancouver:

Jefferson S. Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex. [Internet] [Doctoral dissertation]. University of Florida; 2009. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0023767.

Council of Science Editors:

Jefferson S. Behavioral and Anatomical Plasticity following Low Thoracic Hemisection and Chondroitinase ABC treatment in the Adult Cat Assessments of Locomotion and the Cough Reflex. [Doctoral Dissertation]. University of Florida; 2009. Available from: http://ufdc.ufl.edu/UFE0023767

University of Florida

8. Balasubramanian, Chitralakshmi. Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance.

Degree: PhD, Rehabilitation Science, 2008, University of Florida

URL: http://ufdc.ufl.edu/UFE0022333

► Asymmetrical stepping is a characteristic feature of hemiparetic walking and a result of sensorimotor deficits post-stroke. Asymmetry measures (that is, relative performance of paretic leg)… (more)

▼ Asymmetrical stepping is a characteristic feature of hemiparetic walking and a result of sensorimotor deficits post-stroke. Asymmetry measures (that is, relative performance of paretic leg) may characterize hemiparetic gait better than overall gait performance measures (such as gait speed) and can provide insights into underlying paretic leg impairments. Therefore, the major purpose of this dissertation was to quantify the asymmetry in steps post-stroke and understand its relationship to hemiparetic walking performance. Overall, four studies were conducted. Persons with chronic hemiparesis and healthy controls walked overground and over a split-belt instrumented treadmill as spatiotemporal, kinematic and kinetic data were collected. Clinical assessments included lower-extremity Fugl-Meyer grading and Dynamic Gait Index assessments. In study one, step length asymmetry during walking was quantified. Results showed that step length asymmetry related to propulsive force generation during hemiparetic walking. Further, asymmetrical step lengths may not necessarily limit the self-selected walking speed likely due to other compensatory mechanisms. We suggest that step length asymmetry can be utilized as a clinical measure to evaluate asymmetrical stepping post-stroke. In study two, step-by-step variability and its relation to asymmetrical stepping were investigated. Results showed that increased spatiotemporal variability, asymmetry in swing and pre-swing time variability and reduced width variability were related to severe hemiparesis, asymmetrical stepping and poor balance. We suggest that step-by-step variability measures are quantifiable markers of impaired walking performance post-stroke. In study three, asymmetrical stepping was evaluated in a body reference frame. Results showed that anterior-posterior and medial-lateral foot placements relative to body were asymmetrical and this foot placement asymmetry related to step length asymmetry but not step widths. Wider paretic foot placement relative to pelvis than non-paretic also related to reduced paretic leg weight support and lateral instability, suggesting the clinical utility of medial-lateral foot placement relative to pelvis as an outcome to quantify weight support during hemiparetic walking. In study four, mechanisms underlying step length generation were evaluated. Contralateral anterior-posterior and hip impulses during swing explained the step length variability in the majority of participants. However, relationship of the predictors to step lengths differed in the asymmetrical sub-groups. This implies that mechanisms of step length generation were different across persons showing differing step length asymmetry patterns. Based on these mechanisms, we have proposed specific impairments and therapeutic strategies targeted towards these impairments underlying asymmetrical stepping. ( en ) Advisors/Committee Members: Kautz, Steven A. (committee chair), Behrman, Andrea L. (committee member), Velozo, Craig A. (committee member), Cauraugh, James H. (committee member).

Subjects/Keywords: Asymmetry; Feet; Gait; Kinetics; Legs; Paresis; Pelvis; Propulsion; Strokes; Walking; asymmetry, biomechanics, exercise, gait, quanitification, rehabilitation, step, stepping, stroke, walking

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Balasubramanian, C. (2008). Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0022333

Chicago Manual of Style (16^th Edition):

Balasubramanian, Chitralakshmi. “Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance.” 2008. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0022333.

MLA Handbook (7^th Edition):

Balasubramanian, Chitralakshmi. “Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance.” 2008. Web. 22 Feb 2019.

Vancouver:

Balasubramanian C. Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance. [Internet] [Doctoral dissertation]. University of Florida; 2008. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0022333.

Council of Science Editors:

Balasubramanian C. Quantification of Asymmetrical Stepping Post-Stroke and Its Relationship to Hemiparetic Walking Performance. [Doctoral Dissertation]. University of Florida; 2008. Available from: http://ufdc.ufl.edu/UFE0022333

University of Florida

9. Raja, Bhavana. Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training.

Degree: PhD, Rehabilitation Science, 2010, University of Florida

URL: http://ufdc.ufl.edu/UFE0042166

Subjects/Keywords: Electromyography; Gait; Kinematics; Knees; Legs; Low speed; Paresis; Strokes; Treadmills; Walking; compensation, forces, gait, ground, hemiparetic, locomotor, non, reaction, training

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Raja, B. (2010). Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0042166

Chicago Manual of Style (16^th Edition):

Raja, Bhavana. “Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training.” 2010. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0042166.

MLA Handbook (7^th Edition):

Raja, Bhavana. “Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training.” 2010. Web. 22 Feb 2019.

Vancouver:

Raja B. Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training. [Internet] [Doctoral dissertation]. University of Florida; 2010. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0042166.

Council of Science Editors:

Raja B. Non-Paretic Leg Performance in Hemiparetic Walking: Loading Asymmetries, Compensatory Mechanisms and Responsiveness to Locomotor Training. [Doctoral Dissertation]. University of Florida; 2010. Available from: http://ufdc.ufl.edu/UFE0042166

University of Florida

10. Nair, Preeti Mohandas. Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury.

Degree: PhD, Rehabilitation Science, 2008, University of Florida

URL: http://ufdc.ufl.edu/UFE0021651

► Clinicians often use orthotic devices to compensate for walking related impairments after incomplete spinal cord injury (ISCI). Orthotic devices such as an ankle foot orthosis… (more)

▼ Clinicians often use orthotic devices to compensate for walking related impairments after incomplete spinal cord injury (ISCI). Orthotic devices such as an ankle foot orthosis (AFO) are commonly used to stabilize the ankle joint and aid toe clearance during walking. Compensatory stepping achieved with an AFO has led therapists to assume that such devices could be integrated in newer, neurobiologically driven, recovery-based interventions such as locomotor training (LT) for individuals with ISCI. In spite of the appeal of such compensatory strategies, their use during LT is still controversial. This is due to the lack of information about the possible effect of the device in optimizing or hindering afferent input from lower limb motion; joint, muscle and cutaneous receptors fundamental to the training. After ISCI, pattern generating neural network within the spinal cord increases its reliance on motion-related afferent input from these receptors for maintaining locomotor control. Limiting ankle excursion with an AFO may alter the interconnected limb joint assembly specific to walking and in turn influence the afferent information critical for stepping. Our study explored the therapeutic use of such devices from a walking recovery based paradigm. The aim of this project was to investigate the mechanical and neurophysiological implications of the use of an AFO during stepping in non-injured individuals and persons with ISCI. Specifically, we examined the effect of wearing a posterior leaf spring ankle foot orthosis (PAFO) on transition phase joint kinematics and kinetics and soleus H-reflex modulation during walking. In the first experiment, we examined the transition phase mechanics with and without a PAFO in healthy, non-injured individuals. Our study identified and measured the changes that occurred in normal joint kinematics and kinetics as a result of wearing a PAFO. The results suggested that proximal hip extension; crucial for the transition from stance-to-swing and the rate of loading during the swing- to-stance phase were significantly decreased. In the second experiment, we compared transition phase mechanics observed while walking with and without the PAFO in individuals with ISCI to normal mechanics. The comparison assessed the effect of the PAFO on pre-existing stepping related deficits in individuals with ISCI and also measured deviance or likeness of the change observed in these individuals from normal. The results suggested that the use of a PAFO decreased hip extension thereby impacting the provision of at least one critical afferent input key to the restoration of walking. In the third experiment, soleus H-reflexes were compared in non-injured individuals while walking with and without the PAFO in ten different phases of the gait cycle. The result showed that walking with the PAFO did not affect soleus H-reflex excitability in these individuals. In the fourth and final experiment, soleus H-reflexes were compared in the mid-stance and mid-swing phase in individuals with ISCI, while walking with and… Advisors/Committee Members: Behrman, Andrea L. (committee chair), Kautz, Steven A. (committee member), Rosenbek, John C. (committee member), Thompson, Floyd J. (committee member), Zehr, Paul (committee member).

Subjects/Keywords: Ankle; Ankle joint; Feet; Gait; Kinematics; Knees; Orthotic devices; Physical trauma; Spinal cord; Walking

Record Details Similar Records Cite « Share

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6^th Edition):

Nair, P. M. (2008). Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury. (Doctoral Dissertation). University of Florida. Retrieved from http://ufdc.ufl.edu/UFE0021651

Chicago Manual of Style (16^th Edition):

Nair, Preeti Mohandas. “Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury.” 2008. Doctoral Dissertation, University of Florida. Accessed February 22, 2019. http://ufdc.ufl.edu/UFE0021651.

MLA Handbook (7^th Edition):

Nair, Preeti Mohandas. “Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury.” 2008. Web. 22 Feb 2019.

Vancouver:

Nair PM. Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury. [Internet] [Doctoral dissertation]. University of Florida; 2008. [cited 2019 Feb 22]. Available from: http://ufdc.ufl.edu/UFE0021651.

Council of Science Editors:

Nair PM. Neuromechanical and Neurophysiological Examination of Walking with and without an Ankle Foot Orthosis in Non-Injured Individuals and Persons with Incomplete Spinal Cord Injury. [Doctoral Dissertation]. University of Florida; 2008. Available from: http://ufdc.ufl.edu/UFE0021651

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