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You searched for +publisher:"University of Arizona" +contributor:("Hruby, Victor J"). Showing records 1 – 30 of 75 total matches.

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University of Arizona

1. Nyberg, Joel Benjamin. Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides .

Degree: 2013, University of Arizona

 The melanocortin 3 and 4 receptors share 58% overall amino acid identity and 76% similarity. This high level of similarity between the MC3R and the… (more)

Subjects/Keywords: Melancortins; Melanocortin 3; Melanocortin 3 selective ligands; Peptides; Chemistry; C-terminal modification

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APA (6th Edition):

Nyberg, J. B. (2013). Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/283606

Chicago Manual of Style (16th Edition):

Nyberg, Joel Benjamin. “Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides .” 2013. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/283606.

MLA Handbook (7th Edition):

Nyberg, Joel Benjamin. “Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides .” 2013. Web. 20 Feb 2020.

Vancouver:

Nyberg JB. Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides . [Internet] [Doctoral dissertation]. University of Arizona; 2013. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/283606.

Council of Science Editors:

Nyberg JB. Developing Melanocortin 3 Selective Ligands through C-Terminal Modification of Melanocortin Peptides . [Doctoral Dissertation]. University of Arizona; 2013. Available from: http://hdl.handle.net/10150/283606


University of Arizona

2. Hall, Sara M. Bradykinin Ligands and Receptors Involved in Neuropathic Pain .

Degree: 2015, University of Arizona

 Neuropathic pain is a prevalent disease with no effective, safe treatments and limited knowledge on the mechanisms involved. One target for neuropathic pain treatment may… (more)

Subjects/Keywords: neuropathic pain; non-opioid Dynorphin A; structure activity relationship; Biochemistry; bradykinin receptors

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APA (6th Edition):

Hall, S. M. (2015). Bradykinin Ligands and Receptors Involved in Neuropathic Pain . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/578606

Chicago Manual of Style (16th Edition):

Hall, Sara M. “Bradykinin Ligands and Receptors Involved in Neuropathic Pain .” 2015. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/578606.

MLA Handbook (7th Edition):

Hall, Sara M. “Bradykinin Ligands and Receptors Involved in Neuropathic Pain .” 2015. Web. 20 Feb 2020.

Vancouver:

Hall SM. Bradykinin Ligands and Receptors Involved in Neuropathic Pain . [Internet] [Doctoral dissertation]. University of Arizona; 2015. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/578606.

Council of Science Editors:

Hall SM. Bradykinin Ligands and Receptors Involved in Neuropathic Pain . [Doctoral Dissertation]. University of Arizona; 2015. Available from: http://hdl.handle.net/10150/578606


University of Arizona

3. Ramos-Colon, Cyf Nadine. Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists .

Degree: 2016, University of Arizona

 Millions of people in the US currently suffer from chronic pain but available therapeutics do not provide effective chronic pain treatment. Opiate therapy is still… (more)

Subjects/Keywords: [Des-Arg7] Dynorphin A; Kappa Opioid Receptor Antagonist; Structure Activity Relationships; Pharmaceutical Sciences; Chronic Pain

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APA (6th Edition):

Ramos-Colon, C. N. (2016). Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/621869

Chicago Manual of Style (16th Edition):

Ramos-Colon, Cyf Nadine. “Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists .” 2016. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/621869.

MLA Handbook (7th Edition):

Ramos-Colon, Cyf Nadine. “Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists .” 2016. Web. 20 Feb 2020.

Vancouver:

Ramos-Colon CN. Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists . [Internet] [Doctoral dissertation]. University of Arizona; 2016. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/621869.

Council of Science Editors:

Ramos-Colon CN. Design, Synthesis, and Biological Evaluation of Novel Peptide Ligands as Kappa Opioid Receptor Antagonists . [Doctoral Dissertation]. University of Arizona; 2016. Available from: http://hdl.handle.net/10150/621869


University of Arizona

4. Remesic, Michael Vincent. The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain .

Degree: 2017, University of Arizona

 Chronic neuropathic pain is a disease that impacts the livelihood of millions of people in the United States with no effective pain treatments and limited… (more)

Subjects/Keywords: Bivalent; Bradykinin; Chronic Pain; Multifunctional; Opioid; Peptide

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APA (6th Edition):

Remesic, M. V. (2017). The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/625593

Chicago Manual of Style (16th Edition):

Remesic, Michael Vincent. “The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain .” 2017. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/625593.

MLA Handbook (7th Edition):

Remesic, Michael Vincent. “The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain .” 2017. Web. 20 Feb 2020.

Vancouver:

Remesic MV. The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain . [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/625593.

Council of Science Editors:

Remesic MV. The Design, Synthesis, and Biological Evaluation of Novel Peptidic Ligands for the Treatment of Chronic Neuropathic Pain . [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/625593


University of Arizona

5. Brabez, Nabila. Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells .

Degree: 2012, University of Arizona

 Cancer is lacking early detection methods and treatment specificity. In order to increase the sensitivity and specificity towards cancer cells, we propose the use of… (more)

Subjects/Keywords: multivalent interactions; peptide dendrimers; scaffold; targeted therapy; Chemistry; cancer; GPCR

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APA (6th Edition):

Brabez, N. (2012). Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/238691

Chicago Manual of Style (16th Edition):

Brabez, Nabila. “Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells .” 2012. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/238691.

MLA Handbook (7th Edition):

Brabez, Nabila. “Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells .” 2012. Web. 20 Feb 2020.

Vancouver:

Brabez N. Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells . [Internet] [Doctoral dissertation]. University of Arizona; 2012. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/238691.

Council of Science Editors:

Brabez N. Design, Synthesis and Study of Novel Multivalent Ligands - Toward New Markers of Cancer Cells . [Doctoral Dissertation]. University of Arizona; 2012. Available from: http://hdl.handle.net/10150/238691


University of Arizona

6. Kumarasinghe, Isuru Ransiri. DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN .

Degree: 2010, University of Arizona

 Currently, opioids are extensively used in clinical practices in order to treat pain in patients. However, prolonged administration of opioids are not feasible due to… (more)

Subjects/Keywords: COX 2 inhibitors; mutifunctional molecules; NMR conformational analysis; opioid induced tolerance; Opioids side effects; Substance P antagonist

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APA (6th Edition):

Kumarasinghe, I. R. (2010). DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/193738

Chicago Manual of Style (16th Edition):

Kumarasinghe, Isuru Ransiri. “DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/193738.

MLA Handbook (7th Edition):

Kumarasinghe, Isuru Ransiri. “DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN .” 2010. Web. 20 Feb 2020.

Vancouver:

Kumarasinghe IR. DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/193738.

Council of Science Editors:

Kumarasinghe IR. DESIGN, SYNTHESIS, NMR CONFORMATIONAL ANALYSIS AND DOCKING ANALYSIS OF NOVEL MULTIFUNCTIONAL MOLECULES FOR PAIN . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/193738


University of Arizona

7. Largent- Milnes, Tally Marie. NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD .

Degree: 2010, University of Arizona

 Pain is the most common and debilitating sign of a medical problem, with nearly 15 million patients suffering from chronic pain, including neuropathic pain. Widely… (more)

Subjects/Keywords: antinociceptive tolerance; neurokinin; neuropharmacology; opioid induced hyperalgesia; pain; reward

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APA (6th Edition):

Largent- Milnes, T. M. (2010). NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/193763

Chicago Manual of Style (16th Edition):

Largent- Milnes, Tally Marie. “NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/193763.

MLA Handbook (7th Edition):

Largent- Milnes, Tally Marie. “NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD .” 2010. Web. 20 Feb 2020.

Vancouver:

Largent- Milnes TM. NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/193763.

Council of Science Editors:

Largent- Milnes TM. NEUROKININ 1 RECEPTORS AND THEIR ROLE IN OPIOID-INDUCED HYPERALGESIA, ANTINOCICEPTIVE TOLERANCE AND REWARD . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/193763


University of Arizona

8. Liu, Zhihua. THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS .

Degree: 2010, University of Arizona

 Nature has gifted peptides as important modulators in the human body, but these types of molecules often have not been favored when we were looking… (more)

Subjects/Keywords: Amino Acid; Asymmetric Synthesis; Peptide; Peptidomimetic

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APA (6th Edition):

Liu, Z. (2010). THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/204274

Chicago Manual of Style (16th Edition):

Liu, Zhihua. “THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/204274.

MLA Handbook (7th Edition):

Liu, Zhihua. “THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS .” 2010. Web. 20 Feb 2020.

Vancouver:

Liu Z. THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/204274.

Council of Science Editors:

Liu Z. THE DESIGN AND SYNTHESIS OF NOVEL UNNATURAL AMINO ACIDS AND THE DESIGN AND SYNTHESIS OF PEPTIDES & PEPTIDOMIMETICS CONTAINING UNNATURAL AMINO ACIDS FOR THE STUDY OF G-PROTEIN COUPLED RECEPTORS . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/204274


University of Arizona

9. Olson, Keith Mathew. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .

Degree: 2017, University of Arizona

 Most clinical opioids produce analgesia through the Mu Opioid Receptor (MOR) providing the only effective treatment for chronic pain patients. These studies explore three pre-clinical… (more)

Subjects/Keywords: Bivalent; Delta Opioid Receptor; Functional Selectivity; MDOR Heterodimer; Mu Opioid Receptor; Opioid Signaling

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APA (6th Edition):

Olson, K. M. (2017). Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/626669

Chicago Manual of Style (16th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/626669.

MLA Handbook (7th Edition):

Olson, Keith Mathew. “Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling .” 2017. Web. 20 Feb 2020.

Vancouver:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/626669.

Council of Science Editors:

Olson KM. Atypical Opioid Interactions – Development of Selective Mu-Delta Heterodimer Antagonists, Clinical Opioids at Non-Mu Pain Targets and Endogenous Biased Signaling . [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/626669


University of Arizona

10. Khanal, Pitambar. Crystal Engineering with Piperazinediones .

Degree: 2016, University of Arizona

 Non covalent interactions are valuable tools for crystal engineering. Hydrogen bonding often plays a central role for molecular association among possible non covalent interactions. Together… (more)

Subjects/Keywords: Organic Synthesis; Piperazinediones; Chemistry; Crystal Engineering

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APA (6th Edition):

Khanal, P. (2016). Crystal Engineering with Piperazinediones . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/612051

Chicago Manual of Style (16th Edition):

Khanal, Pitambar. “Crystal Engineering with Piperazinediones .” 2016. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/612051.

MLA Handbook (7th Edition):

Khanal, Pitambar. “Crystal Engineering with Piperazinediones .” 2016. Web. 20 Feb 2020.

Vancouver:

Khanal P. Crystal Engineering with Piperazinediones . [Internet] [Doctoral dissertation]. University of Arizona; 2016. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/612051.

Council of Science Editors:

Khanal P. Crystal Engineering with Piperazinediones . [Doctoral Dissertation]. University of Arizona; 2016. Available from: http://hdl.handle.net/10150/612051


University of Arizona

11. Castillo-Montoya, Javier. Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction .

Degree: 2016, University of Arizona

 The function of most proteins is regulated by post-translational modifications, of which phosphorylation in particular has been shown to be ubiquitous and of paramount importance… (more)

Subjects/Keywords: Kinases; Ligand-Gated Phosphorylation; Protein Engineering; Split-Kinase; Split-Phosphatase; Chemical Inducer of Dimerization

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APA (6th Edition):

Castillo-Montoya, J. (2016). Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/623179

Chicago Manual of Style (16th Edition):

Castillo-Montoya, Javier. “Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction .” 2016. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/623179.

MLA Handbook (7th Edition):

Castillo-Montoya, Javier. “Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction .” 2016. Web. 20 Feb 2020.

Vancouver:

Castillo-Montoya J. Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction . [Internet] [Doctoral dissertation]. University of Arizona; 2016. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/623179.

Council of Science Editors:

Castillo-Montoya J. Development of Orthogonal Split-Kinase and Split-Phosphatase Systems for Interrogating and Rewiring Signal Transduction . [Doctoral Dissertation]. University of Arizona; 2016. Available from: http://hdl.handle.net/10150/623179


University of Arizona

12. Zhou, Yang. Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy .

Degree: 2019, University of Arizona

 Melanocortin receptors are a family of G-protein-coupled receptors (GPCRs) that regulate many important physiological functions. Specifically, melanocortin-1-receptor (MC1R) on skin melanocytes regulates skin pigmentation, which… (more)

Subjects/Keywords: MC1R; melanocortin-1-receptor; melanoma; oral availability; peptide

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APA (6th Edition):

Zhou, Y. (2019). Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/631955

Chicago Manual of Style (16th Edition):

Zhou, Yang. “Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy .” 2019. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/631955.

MLA Handbook (7th Edition):

Zhou, Yang. “Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy .” 2019. Web. 20 Feb 2020.

Vancouver:

Zhou Y. Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy . [Internet] [Doctoral dissertation]. University of Arizona; 2019. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/631955.

Council of Science Editors:

Zhou Y. Development of Selective Peptide Ligands Targeting Melanocortin Receptors for Melanoma Prevention and Therapy . [Doctoral Dissertation]. University of Arizona; 2019. Available from: http://hdl.handle.net/10150/631955


University of Arizona

13. Min, Byoung Joon. PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING .

Degree: 2010, University of Arizona

 beta-Turns in many biologically active peptides are important secondary structural elements which are critical for their biological activities. Hence, it is not surprising that beta-turn… (more)

Subjects/Keywords: beta-turn mimectics; melarnocortin receptor ligands; N-acylimminium ion cyclization; neurokinin receptor ligands; opioid ligands; ring closing metathesis

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APA (6th Edition):

Min, B. J. (2010). PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/194081

Chicago Manual of Style (16th Edition):

Min, Byoung Joon. “PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/194081.

MLA Handbook (7th Edition):

Min, Byoung Joon. “PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING .” 2010. Web. 20 Feb 2020.

Vancouver:

Min BJ. PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/194081.

Council of Science Editors:

Min BJ. PART I. DESIGN AND SYNTHESIS OF BICYCLIC INTERNAL BETA-TURN MIMETICS AND THEIR INCORPORATION INTO BIOLOGICALLY ACTIVE LIGANDS; PART II. SYNTHESIS OF CYCLIC PEPTIDES BY RING . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/194081


University of Arizona

14. Furman, Jennifer Lynn. IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY .

Degree: 2010, University of Arizona

 The ability to directly monitor the presence of specific proteins or nucleic acids in a variety of in vitro and in vivo contexts has great… (more)

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APA (6th Edition):

Furman, J. L. (2010). IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/195828

Chicago Manual of Style (16th Edition):

Furman, Jennifer Lynn. “IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/195828.

MLA Handbook (7th Edition):

Furman, Jennifer Lynn. “IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY .” 2010. Web. 20 Feb 2020.

Vancouver:

Furman JL. IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/195828.

Council of Science Editors:

Furman JL. IN VITRO AND IN VIVO DETECTION OF NUCLEIC ACIDS AND PROTEINS USING SPLIT-PROTEIN REASSEMBLY . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/195828


University of Arizona

15. Shen, Shengyi. Development of Split-protein Systems for Interrogating Biomacromolecules .

Degree: 2013, University of Arizona

 The specific interactions of macromolecules along with the activity of enzymes are central to all aspects of biology. It is well recognized that when the… (more)

Subjects/Keywords: Poly (ADP-ribose); protein kinase; Quantum Dot; split-protein; Chemistry; chemically induced dimerization

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APA (6th Edition):

Shen, S. (2013). Development of Split-protein Systems for Interrogating Biomacromolecules . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/308885

Chicago Manual of Style (16th Edition):

Shen, Shengyi. “Development of Split-protein Systems for Interrogating Biomacromolecules .” 2013. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/308885.

MLA Handbook (7th Edition):

Shen, Shengyi. “Development of Split-protein Systems for Interrogating Biomacromolecules .” 2013. Web. 20 Feb 2020.

Vancouver:

Shen S. Development of Split-protein Systems for Interrogating Biomacromolecules . [Internet] [Doctoral dissertation]. University of Arizona; 2013. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/308885.

Council of Science Editors:

Shen S. Development of Split-protein Systems for Interrogating Biomacromolecules . [Doctoral Dissertation]. University of Arizona; 2013. Available from: http://hdl.handle.net/10150/308885


University of Arizona

16. Skinner, David P. Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 .

Degree: 2014, University of Arizona

 Migraine headache is one of the most common neurological disorders. While the mechanisms contributing to migraine pathophysiology have yet to be fully elucidated, the disproportionate… (more)

Subjects/Keywords: Headache; Migraine; Neurokinin; Medical Pharmacology; Estradiol

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APA (6th Edition):

Skinner, D. P. (2014). Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/321547

Chicago Manual of Style (16th Edition):

Skinner, David P. “Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 .” 2014. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/321547.

MLA Handbook (7th Edition):

Skinner, David P. “Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 .” 2014. Web. 20 Feb 2020.

Vancouver:

Skinner DP. Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 . [Internet] [Doctoral dissertation]. University of Arizona; 2014. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/321547.

Council of Science Editors:

Skinner DP. Hormone Induced "Migraine" and Attempts at Blocking Opiate Reward through NK1 . [Doctoral Dissertation]. University of Arizona; 2014. Available from: http://hdl.handle.net/10150/321547


University of Arizona

17. Anglin, Bobbi Lynn. Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration .

Degree: 2014, University of Arizona

 The incidence of neurodegenerative disorders like Parkinson’s disease (PD) and Alzheimer’s disease (AD) are increasing as the population ages. Slowing the rate of neurological decline… (more)

Subjects/Keywords: neuroprotection; PAC1R; PACAP; Parkinson's disease; Pharmaceutical Sciences; glycopeptide

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APA (6th Edition):

Anglin, B. L. (2014). Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/321595

Chicago Manual of Style (16th Edition):

Anglin, Bobbi Lynn. “Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration .” 2014. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/321595.

MLA Handbook (7th Edition):

Anglin, Bobbi Lynn. “Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration .” 2014. Web. 20 Feb 2020.

Vancouver:

Anglin BL. Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration . [Internet] [Doctoral dissertation]. University of Arizona; 2014. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/321595.

Council of Science Editors:

Anglin BL. Design and Synthesis of PACAP Based Glycopeptide Analogs; Effects of Glycosylation on Activity and Blood-Brain Barrier Penetration . [Doctoral Dissertation]. University of Arizona; 2014. Available from: http://hdl.handle.net/10150/321595


University of Arizona

18. Dehigaspitiya, Dilani Chathurika. Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors .

Degree: 2014, University of Arizona

 The early detection and successful treatment of many human cancers would be facilitated by the availability of reagents that could seek out and selectively bind… (more)

Subjects/Keywords: Chemistry

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APA (6th Edition):

Dehigaspitiya, D. C. (2014). Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/332660

Chicago Manual of Style (16th Edition):

Dehigaspitiya, Dilani Chathurika. “Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors .” 2014. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/332660.

MLA Handbook (7th Edition):

Dehigaspitiya, Dilani Chathurika. “Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors .” 2014. Web. 20 Feb 2020.

Vancouver:

Dehigaspitiya DC. Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors . [Internet] [Doctoral dissertation]. University of Arizona; 2014. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/332660.

Council of Science Editors:

Dehigaspitiya DC. Design, Synthesis, And Testing Of Multivalent Compounds Targeted To Melanocortin Receptors . [Doctoral Dissertation]. University of Arizona; 2014. Available from: http://hdl.handle.net/10150/332660


University of Arizona

19. Nakath Gamlath Ralalage, Dayan Elshan. Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands .

Degree: 2014, University of Arizona

 Peptide receptor overexpression in diseased cells and tissues, including carcinomas provides an opportunity to develop therapeutics and imaging agents that selectively bind to such cells… (more)

Subjects/Keywords: Cholecystokinin; HEK293; Melanocortin; Multivalent; Time resolved fluorescence; Binding assay; Chemistry

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APA (6th Edition):

Nakath Gamlath Ralalage, D. E. (2014). Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/338883

Chicago Manual of Style (16th Edition):

Nakath Gamlath Ralalage, Dayan Elshan. “Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands .” 2014. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/338883.

MLA Handbook (7th Edition):

Nakath Gamlath Ralalage, Dayan Elshan. “Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands .” 2014. Web. 20 Feb 2020.

Vancouver:

Nakath Gamlath Ralalage DE. Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands . [Internet] [Doctoral dissertation]. University of Arizona; 2014. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/338883.

Council of Science Editors:

Nakath Gamlath Ralalage DE. Targeting Melanocortin and Cholecystokinin Receptors via Multivalent Molecules Bearing Peptide Ligands . [Doctoral Dissertation]. University of Arizona; 2014. Available from: http://hdl.handle.net/10150/338883


University of Arizona

20. Lefever, Mark. DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES .

Degree: 2010, University of Arizona

 Our effort to provide an efficient route to serine glycosides with utility in glycopeptide synthesis has led to the identification of two particularly effective promoters… (more)

Subjects/Keywords: glycoside; halide; indium; promoter; scandium

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APA (6th Edition):

Lefever, M. (2010). DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/193791

Chicago Manual of Style (16th Edition):

Lefever, Mark. “DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES .” 2010. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/193791.

MLA Handbook (7th Edition):

Lefever, Mark. “DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES .” 2010. Web. 20 Feb 2020.

Vancouver:

Lefever M. DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES . [Internet] [Doctoral dissertation]. University of Arizona; 2010. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/193791.

Council of Science Editors:

Lefever M. DESIGN, SYNTHESIS AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDES AND FLUORESCENT DERIVATIVES INCLUDING OPTIMIZATION OF SERINE GLYCOSYLATION UTILIZING SUGAR ACETATES . [Doctoral Dissertation]. University of Arizona; 2010. Available from: http://hdl.handle.net/10150/193791


University of Arizona

21. LI, YINGXUE. DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN .

Degree: 2011, University of Arizona

 Structure-activity relationships (SAR) of opioid peptide analogues related to endorphin or dynorphin have provided rational and powerful approaches toward the design of peptide therapeutics. A… (more)

Subjects/Keywords: Chemistry

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APA (6th Edition):

LI, Y. (2011). DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/203033

Chicago Manual of Style (16th Edition):

LI, YINGXUE. “DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN .” 2011. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/203033.

MLA Handbook (7th Edition):

LI, YINGXUE. “DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN .” 2011. Web. 20 Feb 2020.

Vancouver:

LI Y. DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN . [Internet] [Doctoral dissertation]. University of Arizona; 2011. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/203033.

Council of Science Editors:

LI Y. DESIGN, SYNTHESIS, AND CHARACTERIZATION OF HELICAL OPIOID GLYCOPEPTIDE AGONISTS: THE STUDY OF THE STRUCTURE-ACTIVITY RELATIONSHIP AND TRANSPORT OF GLYCOPEPTIDES RELATED TO BETA-ENDORPHIN AND DYNORPHIN . [Doctoral Dissertation]. University of Arizona; 2011. Available from: http://hdl.handle.net/10150/203033


University of Arizona

22. Shekhawat, Sujan Singh. Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly .

Degree: 2011, University of Arizona

 The detection of cellular events is central to understanding biomoleculer processes as well as aid in therapeutic intervention strategies. One of the most fascinating biomoleculer… (more)

Subjects/Keywords: Protease; Split Protein Reassembly; Chemistry; Casapse; Coiled Coils

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APA (6th Edition):

Shekhawat, S. S. (2011). Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/205209

Chicago Manual of Style (16th Edition):

Shekhawat, Sujan Singh. “Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly .” 2011. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/205209.

MLA Handbook (7th Edition):

Shekhawat, Sujan Singh. “Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly .” 2011. Web. 20 Feb 2020.

Vancouver:

Shekhawat SS. Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly . [Internet] [Doctoral dissertation]. University of Arizona; 2011. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/205209.

Council of Science Editors:

Shekhawat SS. Genetically Encoded Sensors for Detection of Proteases Utilizing Auto-Inhibited Coiled Coils and Split-Protein Reassembly . [Doctoral Dissertation]. University of Arizona; 2011. Available from: http://hdl.handle.net/10150/205209


University of Arizona

23. Agasid, Mark Tadashi. I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors .

Degree: 2017, University of Arizona

 Ligand-gated and ligand-modulated ion channel (IC) sensors have received increased attention for their ability to transduce ligand-binding events into a readily measurable electrical signal. Ligand-binding… (more)

Subjects/Keywords: Ion Channel-Coupled Receptors; Kir6.2; Sensors; Ion channels; Black lipid membranes

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APA (6th Edition):

Agasid, M. T. (2017). I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/623173

Chicago Manual of Style (16th Edition):

Agasid, Mark Tadashi. “I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors .” 2017. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/623173.

MLA Handbook (7th Edition):

Agasid, Mark Tadashi. “I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors .” 2017. Web. 20 Feb 2020.

Vancouver:

Agasid MT. I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors . [Internet] [Doctoral dissertation]. University of Arizona; 2017. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/623173.

Council of Science Editors:

Agasid MT. I. Development of Rapid Conductance-Based Protocols for Measuring Ion Channel Activity; II. Expression, Characterization, and Purification of the ATP-Sensitive, Inwardly-Rectifying K+ Channel, Kir6.2, and Ion Channel-Coupled Receptors . [Doctoral Dissertation]. University of Arizona; 2017. Available from: http://hdl.handle.net/10150/623173

24. Kulkarni, Vinod V. Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands .

Degree: 2012, University of Arizona

 Biologically many disease states lead to changes in expressed proteins. Therefore, "system changes" that occur must be considered in any treatment for the disease. This… (more)

Subjects/Keywords: microwave; opioid; peptide cyclization; Chemistry; bifunctional ligands; melanocortin

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APA (6th Edition):

Kulkarni, V. V. (2012). Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/228191

Chicago Manual of Style (16th Edition):

Kulkarni, Vinod V. “Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands .” 2012. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/228191.

MLA Handbook (7th Edition):

Kulkarni, Vinod V. “Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands .” 2012. Web. 20 Feb 2020.

Vancouver:

Kulkarni VV. Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands . [Internet] [Doctoral dissertation]. University of Arizona; 2012. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/228191.

Council of Science Editors:

Kulkarni VV. Novel Bifunctional Ligands For Neuropathic Pain: Design and Synthesis of Overlapping Pharmacophores of Opioid and Melanocortin Ligands . [Doctoral Dissertation]. University of Arizona; 2012. Available from: http://hdl.handle.net/10150/228191


University of Arizona

25. Han, Guoxia. Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches .

Degree: 2000, University of Arizona

 A number of alpha-melanotropin (α-MSH) analogues have been designed de novo, synthesized and bioassayed at different melanocortin receptors from frog skins, mice and humans. These… (more)

Subjects/Keywords: Chemistry, Biochemistry.; Chemistry, Pharmaceutical.

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APA (6th Edition):

Han, G. (2000). Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/284287

Chicago Manual of Style (16th Edition):

Han, Guoxia. “Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches .” 2000. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/284287.

MLA Handbook (7th Edition):

Han, Guoxia. “Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches .” 2000. Web. 20 Feb 2020.

Vancouver:

Han G. Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches . [Internet] [Doctoral dissertation]. University of Arizona; 2000. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/284287.

Council of Science Editors:

Han G. Design, synthesis, pharmacology, and structural analysis of bioactive melanocortin receptors' ligands by hybrid approaches . [Doctoral Dissertation]. University of Arizona; 2000. Available from: http://hdl.handle.net/10150/284287


University of Arizona

26. Ahn, Jung-Mo. Search for bioactive conformation of glucagon and development of potent glucagon antagonists .

Degree: 2000, University of Arizona

 In pursuit of the working model of how glucagon interacts with the glucagon receptor and how glucagon antagonists exert their different activities, 42 glucagon analogues… (more)

Subjects/Keywords: Chemistry; Organic.

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APA (6th Edition):

Ahn, J. (2000). Search for bioactive conformation of glucagon and development of potent glucagon antagonists . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/284301

Chicago Manual of Style (16th Edition):

Ahn, Jung-Mo. “Search for bioactive conformation of glucagon and development of potent glucagon antagonists .” 2000. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/284301.

MLA Handbook (7th Edition):

Ahn, Jung-Mo. “Search for bioactive conformation of glucagon and development of potent glucagon antagonists .” 2000. Web. 20 Feb 2020.

Vancouver:

Ahn J. Search for bioactive conformation of glucagon and development of potent glucagon antagonists . [Internet] [Doctoral dissertation]. University of Arizona; 2000. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/284301.

Council of Science Editors:

Ahn J. Search for bioactive conformation of glucagon and development of potent glucagon antagonists . [Doctoral Dissertation]. University of Arizona; 2000. Available from: http://hdl.handle.net/10150/284301


University of Arizona

27. Alfaro-Lopez, Lorenzo Josue. Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands .

Degree: 1999, University of Arizona

 Based on the efficient substrate for p60ᶜ⁻ˢʳᶜ protein tyrosine kinase (PTK) YIYGSFK (1) (K(m) = 55 μM) obtained by combinatorial methods, we have designed and… (more)

Subjects/Keywords: Chemistry, Organic.; Chemistry, Pharmaceutical.

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APA (6th Edition):

Alfaro-Lopez, L. J. (1999). Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/288981

Chicago Manual of Style (16th Edition):

Alfaro-Lopez, Lorenzo Josue. “Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands .” 1999. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/288981.

MLA Handbook (7th Edition):

Alfaro-Lopez, Lorenzo Josue. “Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands .” 1999. Web. 20 Feb 2020.

Vancouver:

Alfaro-Lopez LJ. Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands . [Internet] [Doctoral dissertation]. University of Arizona; 1999. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/288981.

Council of Science Editors:

Alfaro-Lopez LJ. Development of new conformationally and topographically constrained p60(c-src) PTK inhibitors. Solution and solid-phase approaches for the synthesis of delta-opioid receptor peptidomimetic ligands . [Doctoral Dissertation]. University of Arizona; 1999. Available from: http://hdl.handle.net/10150/288981


University of Arizona

28. Gu, Xuyuan. The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides .

Degree: 2003, University of Arizona

 Peptide ligands represent the most important hormones and neurotransmitters in physiological processes. Although native biologically active peptides have a great potential for medical applications, they… (more)

Subjects/Keywords: Chemistry, Organic.; Chemistry, Pharmaceutical.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Gu, X. (2003). The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/289938

Chicago Manual of Style (16th Edition):

Gu, Xuyuan. “The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides .” 2003. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/289938.

MLA Handbook (7th Edition):

Gu, Xuyuan. “The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides .” 2003. Web. 20 Feb 2020.

Vancouver:

Gu X. The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides . [Internet] [Doctoral dissertation]. University of Arizona; 2003. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/289938.

Council of Science Editors:

Gu X. The design and synthesis of novel amino acids and their usein synthesis of beta-turn mimetics and their incorporation into biological active peptides . [Doctoral Dissertation]. University of Arizona; 2003. Available from: http://hdl.handle.net/10150/289938


University of Arizona

29. Zhang, Junyi. Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics .

Degree: 2003, University of Arizona

 A central goal of modern biology is to develop a detailed, predictive understanding of the relationships of three-dimensional structure and biological function. However, to establish… (more)

Subjects/Keywords: Chemistry; Organic.

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APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Zhang, J. (2003). Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/289964

Chicago Manual of Style (16th Edition):

Zhang, Junyi. “Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics .” 2003. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/289964.

MLA Handbook (7th Edition):

Zhang, Junyi. “Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics .” 2003. Web. 20 Feb 2020.

Vancouver:

Zhang J. Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics . [Internet] [Doctoral dissertation]. University of Arizona; 2003. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/289964.

Council of Science Editors:

Zhang J. Design and stereoselective synthesis of novel bicyclicbeta-turn dipeptide mimetics and cis-4-substitutedproline analogues for peptides and peptidomimetics . [Doctoral Dissertation]. University of Arizona; 2003. Available from: http://hdl.handle.net/10150/289964


University of Arizona

30. Ndungu, John M. The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides .

Degree: 2004, University of Arizona

 Peptide ligands and protein receptors play critical roles in the regulation of nearly every biological system. However, peptides are characteristically highly flexible and thus identifying… (more)

Subjects/Keywords: Chemistry; Organic.

Record DetailsSimilar RecordsGoogle PlusoneFacebookTwitterCiteULikeMendeleyreddit

APA · Chicago · MLA · Vancouver · CSE | Export to Zotero / EndNote / Reference Manager

APA (6th Edition):

Ndungu, J. M. (2004). The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides . (Doctoral Dissertation). University of Arizona. Retrieved from http://hdl.handle.net/10150/290126

Chicago Manual of Style (16th Edition):

Ndungu, John M. “The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides .” 2004. Doctoral Dissertation, University of Arizona. Accessed February 20, 2020. http://hdl.handle.net/10150/290126.

MLA Handbook (7th Edition):

Ndungu, John M. “The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides .” 2004. Web. 20 Feb 2020.

Vancouver:

Ndungu JM. The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides . [Internet] [Doctoral dissertation]. University of Arizona; 2004. [cited 2020 Feb 20]. Available from: http://hdl.handle.net/10150/290126.

Council of Science Editors:

Ndungu JM. The design and synthesis of novel beta-substituted amino acids, bicyclic dipeptide mimetics, and their incorporation into cholecystokinin/opioidchimeric peptides . [Doctoral Dissertation]. University of Arizona; 2004. Available from: http://hdl.handle.net/10150/290126

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