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University of Adelaide
1.
Jayaram, Lata.
Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort.
Degree: 2010, University of Adelaide
URL: http://hdl.handle.net/2440/63531
► Induced sputum examination (IS), an established research tool to measure airway inflammation (AI), is normally confined to specialised institutions and selected populations with airway disease,…
(more)
▼ Induced sputum examination (IS), an established research tool to measure airway inflammation (AI), is normally confined to specialised institutions and selected populations with airway disease, especially asthma. This thesis examines the role of IS in the diagnosis of asthma in a community.
The first study explores the accepted definitions of asthma, the utility of IS, and another marker of AI, exhaled nitric oxide (eNO), in establishing the diagnosis of asthma. The findings confirm that symptoms, variable airflow obstruction and airway hyper-responsiveness (AHR) are inter-linked in the definition of asthma. Bronchodilator reversibility (BDR), used traditionally, remains the most specific test to aid a diagnosis of asthma in the community. The results favour a tailored approach in the diagnosis of asthma using BDR initially, then selecting a test, either eNO or IS depending on the clinical scenario. The usefulness of AHR with hypertonic saline to diagnose asthma is equivocal given the moderate sensitivity and poor specificity of the test documented within. If a global assessment of AI is required, an eNO measurement is recommended initially, given its ease of use. Sputum examination is useful in delineating the subtype of AI present.
Dyspnoea is a cardinal symptom in asthma. Studies have shown a correlation between AI measured by IS and an altered perception of dyspnoea (POD) in selected subjects with asthma. The aim of the second and third studies was to determine if a similar relationship exists in subjects with and without AHR from a community sample. In both groups, increasing POD was related to worsening lung function and increased BMI. Increased POD was also associated with poorer psychosocial and economic outcomes in subjects with AHR. In the context of previous research, these results illustrate that heightened POD itself, rather than asthma, is associated with these outcomes. Sputum eosinophilia was not associated with an altered POD in subjects with and without asthma.
There has been mounting research establishing the role of zinc as an immunomodulator in asthma. Mouse models have demonstrated that zinc deficiency is associated with airway eosinophilia. Two pools of zinc exist in the body: largely fixed, enzyme-bound zinc, and free or labile zinc, the biologically active component. With zinc deficiency, it is the latter pool that is preferentially depleted. Our laboratory has developed a novel method, Zinquin fluorometry, allowing measurement of labile zinc in body fluids. The final two studies demonstrate that IS lends itself to labile zinc measurements. Zinquin fluorometry was optimised to measure free pools of zinc in sputum. It was then used to quantify labile sputum zinc concentrations in subjects with and without asthma. Lower zinc concentrations were found in the sputum of subjects with asthma and a significant association noted between lower zinc concentrations and worsening asthma severity.
From a community perspective, these findings suggest that while IS has a limited role in diagnosing…
Advisors/Committee Members: Ruffin, Richard Ernest (advisor), Zalewski, Peter Ernest (advisor), Adams, Robert R. (advisor), School of Medicine (school).
Subjects/Keywords: asthma; airway inflammation; zinc levels in sputum
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APA (6th Edition):
Jayaram, L. (2010). Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/63531
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Jayaram, Lata. “Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort.” 2010. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/63531.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Jayaram, Lata. “Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort.” 2010. Web. 27 Feb 2021.
Vancouver:
Jayaram L. Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort. [Internet] [Thesis]. University of Adelaide; 2010. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/63531.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Jayaram L. Airway inflammation, diagnosis, perception of asthma, and sputum zinc levels in a community cohort. [Thesis]. University of Adelaide; 2010. Available from: http://hdl.handle.net/2440/63531
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide
2.
Newbury, Wendy Lynne.
Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.
Degree: 2013, University of Adelaide
URL: http://hdl.handle.net/2440/83639
► Spirometry is used to diagnose respiratory disease, to monitor disease progression and response to treatment, and in epidemiological surveys. As a large burden of disease…
(more)
▼ Spirometry is used to diagnose respiratory disease, to monitor disease progression and response to treatment, and in epidemiological surveys. As a large burden of disease is caused by cigarette smoking, spirometry has been incorporated in smoking cessation counselling in an attempt to improve quit rates. The concept of lung age (LA) was developed in 1985 in an effort to make spirometry results more easily understood by the lay person. Research results using LA to aid quitting remain inconclusive. This thesis investigates the need to update LA equations, as predictive equations based on old data may not be relevant for today’s populations, and contemporary equations may result in a stronger message for smokers. New LA equations were firstly developed using contemporary Australian data and four further LA equations were derived from previously published FEV₁ predictive equations. A series of comparisons of LA equations in contemporary Australian datasets followed. The first project compared the original Morris LA equations with newly developed Australian LA equations in an independent workplace dataset (males only). The second project compared four extra LA equations derived from previously published FEV₁ equations from Europe, the United Kingdom, America and Australia with the Morris and the new Australian equations. An independent dataset of randomly-selected males and females was used to compare these equations with the Morris LA equations and contemporary Australian LA equations. Lastly, a different type of LA equation expressed as delta lung age (ΔLA), the difference between chronological age and lung age, based on the ratio of Forced Expiratory Volume in one second/Forced Vital Capacity (FEV₁/FVC), was compared with three other LA equations based on FEV₁ alone. This project used three independent datasets (urban, rural and a workplace) for added strength. All LA equations confirmed poorer lung function in smokers than in never smokers in all 3 independent datasets. LA estimates were approximately 20 years lower using the original Morris equations when compared with the newest LA equations. The differences seen between estimated LA using all six equations were consistent in each analysis. The ΔLA equation gave extreme LA estimates in both the community-based datasets compared with the LA equations based on FEV₁ alone. These results show that the Morris LA equations need to be updated. However, there appears to be no advantage in using the ΔLA equation. The differences between the older and the newer LA equations are most likely a result of cohort and period effects. This is also the case in the predictive equations themselves. Continuously updating predictive equations using recently acquired data will result in LA equations that are more relevant to contemporary populations.
Advisors/Committee Members: Crockett, Alan Joseph (advisor), Ruffin, Richard Ernest (advisor), School of Population Health (school).
Subjects/Keywords: spirometry; lung age; predictive equations; smoking cessation; COPD; lung function
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Newbury, W. L. (2013). Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/83639
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Newbury, Wendy Lynne. “Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.” 2013. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/83639.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Newbury, Wendy Lynne. “Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept.” 2013. Web. 27 Feb 2021.
Vancouver:
Newbury WL. Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. [Internet] [Thesis]. University of Adelaide; 2013. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/83639.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Newbury WL. Exploring the currency of spirometric predictive equations from the viewpoint of the lung age concept. [Thesis]. University of Adelaide; 2013. Available from: http://hdl.handle.net/2440/83639
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
3.
Roscioli, Eugene.
Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways.
Degree: 2014, University of Adelaide
URL: http://hdl.handle.net/2440/90337
► Asthma is potentiated by complex gene-environment interactions, and characterised by inflammation and degenerative changes to the conducting airways. Current therapeutics targeting the inflammation and bronchoconstriction…
(more)
▼ Asthma is potentiated by complex gene-environment interactions, and characterised by inflammation and degenerative changes to the conducting airways. Current therapeutics targeting the inflammation and bronchoconstriction are restricted to prophylactic effects. The airway epithelium is known to participate in the pathogenesis of asthma, and represents a therapeutic target. Airway epithelial cells (AEC) from asthmatics exhibit apoptotic changes, which correlate with disease-associated factors presented by the epithelium. However, the mechanisms which cause the apoptosis are not well defined. In particular, there has been little study of the role of the family of Inhibitor of Apoptosis Proteins (IAPs) in models of AEC apoptosis. The over-arching hypothesis in this thesis is that anomalies in one or more of the IAPs contribute to inflammation-induced AE apoptosis in asthma. Experiments in this thesis explored the role of XIAP, cIAP1 and cIAP2 in asthma, models of asthma-related inflammation, and genetic susceptibility to asthma. The major methods used in these experiments included cell culture of primary AEC from both asthmatics and controls with/without treatment with IFNγ and TNFα. siRNA knockdown, qPCR, western blotting, immunocytochemistry, functional caspase assays, and genotyping. The major findings of this study are i) surprisingly, primary AECs do not undergo apoptosis after prolonged exposure to the proinflammatory cytokines IFNγ and TNFα ex vivo; ii) rather, IFNγ elicits a proapoptotic state in AECs, evidenced by, partial processing of procaspase-3, the absence of Poly (ADP-ribose) polymerase (PARP) cleavage, an increased Bax:Bcl2 transcript ratio, and the absence of morphological changes associated with apoptosis; iii) both XIAP and cIAP1 were constitutively expressed in AEC, and protein levels were unaffected by cytokine treatment. In contrast cIAP2, initially weakly expressed, was strongly inducible by cytokine treatment; iv) No differences were observed between AEC from asthmatics and controls in terms of either basal IAP gene expression levels or their response to cytokine treatment; v) siRNA-mediated depletion of cIAP2- transcripts allows AEC to progress into apoptosis after extended culture, conditions which also resulted in a decrease in both cIAP1 and Bcl2; vi) genetic polymorphism in the genes encoding, XIAP cIAP1 and cIAP2 do not associate with susceptibility for asthma. However, cIAP1 polymorphism may modulate disease severity within asthmatics. This thesis contributes to the knowledge of IAPs and apoptosis in asthma, and provides evidence that they are important for sustaining AEC survival, and participate within a cooperative of endogenous regulators of apoptosis. There is no evidence of intrinsic dysregulation of IAPs in asthma, yet cIAP1 polymorphism may modulate asthma severity, and IAPs are central in maintaining a proapoptotic state in AECs exposed to asthma related cytokines. Epithelial activation and damage, coupled with non-progression to apoptosis may contribute to fragility of the AE…
Advisors/Committee Members: Zalewski, Peter Ernest (advisor), Lester, Susan (advisor), Ruffin, Richard Ernest (advisor), School of Medicine (school).
Subjects/Keywords: apoptosis; asthma; IAP; epithelial; inflammation
…institution without the prior
approval of the University of Adelaide and where applicable, any… …recipient ($24,000) for The University of Adelaide
postgraduate certificate in…
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Roscioli, E. (2014). Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/90337
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Roscioli, Eugene. “Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways.” 2014. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/90337.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Roscioli, Eugene. “Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways.” 2014. Web. 27 Feb 2021.
Vancouver:
Roscioli E. Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways. [Internet] [Thesis]. University of Adelaide; 2014. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/90337.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Roscioli E. Inhibitor of apoptosis proteins as regulatory factors in the normal and inflamed airways. [Thesis]. University of Adelaide; 2014. Available from: http://hdl.handle.net/2440/90337
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide
4.
Crockett, Alan Joseph.
The impact of long term oxygen therapy on South Australian patients with chronic lung disease.
Degree: 2005, University of Adelaide
URL: http://hdl.handle.net/2440/37767
► The peer-reviewed publications contained within this thesis describe studies that have contributed significantly to the understanding of long-term oxygen therapy (LTOT) for Australian Chronic Obstructive…
(more)
▼ The peer-reviewed publications contained within this thesis describe studies that have contributed significantly to the understanding of long-term oxygen therapy (LTOT) for Australian Chronic Obstructive Pulmonary Disease (COPD) patients. My personal contribution to each of these studies ranged from the initial development of the hypotheses and design and execution of the investigations, submission of research grants applications to fund the studies through to preparation of the manuscripts for publication. When LTOT was first introduced into Australia I was fortunate to meet the key experts in LTOT including Professors Tom Petty, Nick Anthonisen, David Flenley, Pierre Levi-Valensi and Peter Howard. At that time all were involved in randomised controlled trials of oxygen therapy. (1, 2), 3). I also visited several oxygen concentrator and oxygen supply companies in the USA and UK. It was during these visits that I became convinced that the concentrator provided a more economical and efficient method of LTOT delivery. In 1980, an oxygen concentrator was imported to Australia by the spouse of one of our patients suffering from emphysema who was receiving long term oxygen via cylinders In 1982, two oxygen concentrators were donated to FMC by two different manufacturers (DeVilbis and Marx) based in the USA. These instruments were trialled on a male and female patient receiving LTOT in the Southern
Adelaide metropolitan area. The initial acceptance of this device by these patients led to a submission to the South Australian Department of Health for a grant to purchase 40 units. Funds were finally obtained for the purchase of 34 concentrators by FMC and these were rolled out to the then existing patients who were receiving LTOT in 1984. Up to this point in time the only published guidelines or recommendations for LTOT came from the American College of Chest Physicians in 1973(3) and the American Thoracic Society in 1977(4). In 1982, the staff of the Respiratory Unit, FMC held a workshop where it was agreed that patients' would be assessed for home oxygen therapy using the 1977 American Thoracic Society Guideline. The late Professor Ann Woolcock presented a paper during a 1983 symposium titled "Long Term Oxygen Therapy: A World View" during a 1983 symposium held in Toronto, Canada where she estimated that at that time 2,100 patients were receiving oxygen in New South Wales for an average of 1 hour per day. She further reported that the use of cylinders ranged from 1 cylinder a year to 14 cylinders per week. Physicians were reported to have been conservative in their approach to oxygen therapy and that only 50 people were on long term oxygen therapy in New South Wales. Presumably the vast majority of these patients were receiving intermittent oxygen therapy. Woolcock mentioned that oxygen concentrators were available but provided no specific detail of their use in Australia(5). The first Australian guideline for the provision of domiciliary long-term oxygen therapy appeared in 1985. This guideline was developed at the request…
Advisors/Committee Members: Ruffin, Richard Ernest (advisor), Beilby, Justin John (advisor), School of Population Health and Clinical Practice (school).
Subjects/Keywords: oxygen therapy; lungs
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Crockett, A. J. (2005). The impact of long term oxygen therapy on South Australian patients with chronic lung disease. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/37767
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Crockett, Alan Joseph. “The impact of long term oxygen therapy on South Australian patients with chronic lung disease.” 2005. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/37767.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Crockett, Alan Joseph. “The impact of long term oxygen therapy on South Australian patients with chronic lung disease.” 2005. Web. 27 Feb 2021.
Vancouver:
Crockett AJ. The impact of long term oxygen therapy on South Australian patients with chronic lung disease. [Internet] [Thesis]. University of Adelaide; 2005. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/37767.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Crockett AJ. The impact of long term oxygen therapy on South Australian patients with chronic lung disease. [Thesis]. University of Adelaide; 2005. Available from: http://hdl.handle.net/2440/37767
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide
5.
Moran, John Leith.
Statistical issues in the analysis of outcomes in critical care medicine.
Degree: 2006, University of Adelaide
URL: http://hdl.handle.net/2440/37805
► 1.1 The focus of this thesis will be the nexus of statistical methods and clinical practice, as it applies to Critical Care Medicine and is…
(more)
▼ 1.1 The focus of this thesis will be the nexus of statistical methods and clinical practice, as it applies to Critical Care Medicine and is reflected in the literature ( for instance : Anaesthesia and Intensive Care ( Anaesthesia and Intensive Care 2005 ) and Critical Care & Resuscitation ( Critical Care and Resuscitation 2005 ) in Australia ; and internationally : Critical Care Medicine ( Critical Care Medicine 2005 ), Intensive Care Medicine ( Intensive Care Medicine 2005 ), Chest ( Chest 2005 ), American Journal of Respiratory and Critical Care Medicine ( American Journal of Respiratory and Critical Care Medicine 2005 ) and Journal of the American Medical Association ( JAMA 2005 ) ).
1.2 Altman has documented the career of statistics in medical journals over a 20 year period and has lamented the general state of affairs ( Altman 1982 ; Altman 1991b ; Altman 1994 ; Altman 2000 ). The transfer of statistical techniques into medical literature is characterised by a significant lag - time ( Altman et al. 1994b ) and statistical input into medical research and publication, although " widely recommended ... ( is ) ... inconsistently obtained " ( Altman et al. 2002 ), perhaps reflecting an undervaluation of statistical contributions to medicine, as articulated by one of the doyen ' s of biostatistics, Norman Breslow ( Breslow 2003 ). The latter observed that, as opposed to the awarding of a Nobel Prize ( in 2000 ) to econometricians Daniel McFadden and James Heckman for work on discrete choice models and selection bias, similar contributions to medicine by statisticians and epidemiologists have been, as yet, unrecognized.
1.3 Our comparators in statistical " critique " ( Berk 2004 ; BROSS 1960 ) are drawn from analytic approaches, more than thirty years apart. First, the lucid contributions of Jerome Cornfield ( Greenhouse 1982 ) ; in particular : the classic intervention ( in 1959 ) into the tobacco smoking / lung cancer debate " Smoking and lung cancer : recent evidence and a discussion of some questions " ( Cornfield et al. 1959 ) ; and " Further statistical analysis of the mortality findings " of the
University Group Diabetes Program ( Cornfield 1971 ), which was an elegant response to the controversy which raged ( for some years ( Kolata 1979 ) ) over the discontinuance of tolbutamide and diet arm in that trial. The textual lucidity to which we refer was presumably a function of the literary background of Cornfield, as documented in the classic review by Salsburg of the rise of the modern statistical paradigm in the twentieth century ( Salsburg 2001 ). Second, the muscular re - examination, or rather, dissection, by Freedman et al ( Freedman et al. 2004 ) of the controversy surrounding breast cancer screening and its efficacy ; being a detailed reading of the meta - analysis by Gotszche and Olsen ( Gotzsche et al. 2000 ), who had questioned the role of mammography in breast cancer screening in terms of potential lives saved. Third, the subtle 1994 reappraisal by Petitti of the mortality treatment effect of patient…
Advisors/Committee Members: Ruffin, Richard Ernest (advisor), Solomon, Patricia Joy (advisor), School of Medicine (school).
Subjects/Keywords: emergency medicine; medical statistics; critical care medicine
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Moran, J. L. (2006). Statistical issues in the analysis of outcomes in critical care medicine. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/37805
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Moran, John Leith. “Statistical issues in the analysis of outcomes in critical care medicine.” 2006. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/37805.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Moran, John Leith. “Statistical issues in the analysis of outcomes in critical care medicine.” 2006. Web. 27 Feb 2021.
Vancouver:
Moran JL. Statistical issues in the analysis of outcomes in critical care medicine. [Internet] [Thesis]. University of Adelaide; 2006. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/37805.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Moran JL. Statistical issues in the analysis of outcomes in critical care medicine. [Thesis]. University of Adelaide; 2006. Available from: http://hdl.handle.net/2440/37805
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation

University of Adelaide
6.
Taylor, Anne Winifred.
Representative population health surveys : improving public health through rigour, diversity of methods and collaboration.
Degree: 2006, University of Adelaide
URL: http://hdl.handle.net/2440/37891
► Prevention and slowing the progression, of chronic diseases ( such as cancer, heart disease, arthritis, diabetes, asthma, osteoporosis, dementia and incontinence ), and influencing risk…
(more)
▼ Prevention and slowing the progression, of chronic diseases ( such as cancer, heart disease, arthritis, diabetes, asthma, osteoporosis, dementia and incontinence ), and
influencing risk factors and health behaviours of a population, relies on the best available data - driven evidence. The quality of measurement techniques to collect representative population health survey and surveillance data is, as a consequence, brought under scrutiny. The presentation of this thesis is the culmination of 17 years work that has been focused on contributing to improving public health in South Australia. It is premised on the understanding that continual epidemiological assessment using representative population health surveys can deliver evidence - based information needed by health policy makers, health planners and health promoters to make appropriate, timely and efficient evidence - based decisions. The objective of the portfolio of published papers was to demonstrate the contribution to producing quality data - driven evidence using population surveys through rigour in collecting self - reported data, diversifying surveillance data collection methods and facilitating collaboration. This portfolio presents papers that have addressed a range of methodological and chronic disease and risk factor epidemiological issues. In terms of demonstrating rigour the publications have addressed the bias associated with non - response, the methodological rigour inherent in face - to - face surveys, the differences in estimates that can occur based on mode of administration, the science of telephone surveying and the importance of good questionnaire design to produce valid and meaningful data. The literature presented has also demonstrated the first South Australian population - wide prevalence survey dealing with the consequences of domestic violence and associated issues ( for males and females ) in the community, and in doing so, demonstrated the use of the telephone to collect large - scale data in Australia on domestic violence and associated factors in the population. In
addition, the first time the importance of undertaking an array of methodological precautions during the data collection phase associated with collecting data on sensitive health issues on the telephone was demonstrated in Australia as was the assessment of the bias obtained in health estimates dependent upon which telephone - based sample was used. In demonstrating the need for diversity in data collection the research submitted within this thesis has demonstrated the range of telephone surveying development issues and challenges in Australia and the benefits and the value of both face - to - face and telephone as survey data collection tools in Australia. The publications also made a significant contribution to the literature in the survey methodology area, in particular, within the systematic error in questionnaire design, the measurement error in BMI self - reported measurements, validity of self - reported height and weight, and the overall CATI methodology area.…
Advisors/Committee Members: Ruffin, Richard Ernest (advisor), Wilson, David (advisor), Adams, Bob (advisor), School of Medicine (school).
Subjects/Keywords: Health surveys; Public health surveillance; Health status indicators; Epidemiology; Telephone surveys; Questionnaires Design
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❌
APA ·
Chicago ·
MLA ·
Vancouver ·
CSE |
Export
to Zotero / EndNote / Reference
Manager
APA (6th Edition):
Taylor, A. W. (2006). Representative population health surveys : improving public health through rigour, diversity of methods and collaboration. (Thesis). University of Adelaide. Retrieved from http://hdl.handle.net/2440/37891
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Chicago Manual of Style (16th Edition):
Taylor, Anne Winifred. “Representative population health surveys : improving public health through rigour, diversity of methods and collaboration.” 2006. Thesis, University of Adelaide. Accessed February 27, 2021.
http://hdl.handle.net/2440/37891.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
MLA Handbook (7th Edition):
Taylor, Anne Winifred. “Representative population health surveys : improving public health through rigour, diversity of methods and collaboration.” 2006. Web. 27 Feb 2021.
Vancouver:
Taylor AW. Representative population health surveys : improving public health through rigour, diversity of methods and collaboration. [Internet] [Thesis]. University of Adelaide; 2006. [cited 2021 Feb 27].
Available from: http://hdl.handle.net/2440/37891.
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
Council of Science Editors:
Taylor AW. Representative population health surveys : improving public health through rigour, diversity of methods and collaboration. [Thesis]. University of Adelaide; 2006. Available from: http://hdl.handle.net/2440/37891
Note: this citation may be lacking information needed for this citation format:
Not specified: Masters Thesis or Doctoral Dissertation
.